GELTEX PHARMACEUTICALS INC
10-Q, 1999-08-16
PHARMACEUTICAL PREPARATIONS
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<PAGE>   1
                                    FORM 10-Q

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

           (X) QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
                       SECURITIES AND EXCHANGE ACT OF 1934

                  For the quarterly period ended June 30, 1999

                                       OR

           ( ) TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
                       SECURITIES AND EXCHANGE ACT OF 1934


              For the transition period from _________ to _________


                         Commission file number 0-26872


                          GELTEX PHARMACEUTICALS, INC.
             (Exact name of registrant as specified in its charter)


                DELAWARE                                  04-3136767
    (State or other jurisdiction of            (IRS Employer Identification No.)
     incorporation or organization)

           NINE FOURTH AVENUE
         WALTHAM, MASSACHUSETTS                              02451
(Address of principal executive offices)                  (Zip Code)


                                  781-290-5888
              (Registrant's telephone number, including area code)


Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months (or for such shorter period that the registrant was
required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days. Yes (X) No ( )

The number of shares outstanding of each of the issuer's classes of common stock
as of the latest practicable date:

                CLASS                           OUTSTANDING AT JULY 28, 1999
                -----                           ----------------------------

    Common Stock, $.01 par value                         16,881,800



<PAGE>   2




                          GELTEX PHARMACEUTICALS, INC.

                                TABLE OF CONTENTS

<TABLE>
<CAPTION>
                                                                                                                PAGE NO
                                                                                                                -------
<S>                                                                                                               <C>
PART I   FINANCIAL INFORMATION

         ITEM 1 Financial Statements

                Condensed Balance Sheets as of June 30, 1999 and December 31, 1998.............................    3

                Condensed Statements of Operations for the three months ended June 30, 1999 and 1998...........    4

                Condensed Statements of Operations for the six months ended June 30, 1999 and 1998.............    4

                Condensed Statements of Comprehensive Loss for the three months ended June 30, 1999 and 1998...    5

                Condensed Statements of Comprehensive Loss for the six months ended June 30, 1999 and 1998.....    5

                Condensed Statements of Cash Flows for the six months ended June 30, 1999 and 1998.............    6

                Notes to Condensed Financial Statements........................................................    7

         ITEM 2 Management's Discussion and Analysis of Financial Condition and Results of  Operations.........    8

         ITEM 3 Quantitative and Qualitative Disclosures About Market Risk.....................................   10


PART II  OTHER INFORMATION

         ITEM 4 Submission of Matters to a Vote of Security Holders............................................   11

         ITEM 5 Other Information..............................................................................   11

         ITEM 6 Exhibits and Reports on Form 8-K...............................................................   12

SIGNATURE......................................................................................................   13

EXHIBIT INDEX..................................................................................................   14
</TABLE>






                                      -2-
<PAGE>   3


                          PART I. FINANCIAL INFORMATION

ITEM 1. FINANCIAL STATEMENTS

                          GELTEX PHARMACEUTICALS, INC.

                            CONDENSED BALANCE SHEETS
                                   (UNAUDITED)

<TABLE>
<CAPTION>
                                                                                      JUNE 30,         DECEMBER 31,
                                                                                        1999               1998
                                                                                    ------------       ------------
<S>                                                                                 <C>                <C>
ASSETS
Current assets:
    Cash and cash equivalents ..................................................    $  7,814,696       $ 30,874,900
     Marketable securities .....................................................      70,657,590         74,077,436
     Prepaid expenses and other current assets .................................       2,821,311          2,708,487
     Due from affiliates .......................................................      10,251,100         10,251,100
     Due from Joint Venture ....................................................         444,679          1,128,124
     Inventory .................................................................       3,186,113                 --
                                                                                    ------------       ------------
Total current assets ...........................................................      95,175,489        119,040,047
Long-term receivables, affiliates ..............................................         470,000            470,000
Long-term receivables ..........................................................           1,591             32,725
Property and equipment, net ....................................................       7,712,919          7,899,470
Intangible assets, net .........................................................       1,050,229            818,963
Investment in Joint Venture ....................................................       9,064,919          5,183,580
                                                                                    ------------       ------------
                                                                                    $113,475,147       $133,444,785
                                                                                    ============       ============

LIABILITIES AND STOCKHOLDERS' EQUITY:
Current liabilities:
     Accounts payable and accrued expenses .....................................    $  4,450,295          4,848,728
     Due to Joint Venture ......................................................              --          1,349,400
     Current portion of long-term obligations ..................................         840,808          2,020,614
                                                                                    ------------       ------------
Total current liabilities ......................................................       5,291,103          8,218,742
Long-term obligations, less current portion ....................................       5,206,180          5,206,180
Commitments and contingencies ..................................................              --                 --
Stockholders' equity:
     Common Stock, $.01 par value, 50,000,000 shares authorized;
     16,865,180 and 16,792,444 shares issued and outstanding
     at June 30, 1999 and December 31, 1998, respectively ......................         168,652            167,924
     Additional paid-in capital ................................................     187,104,318        186,762,715
     Deferred compensation .....................................................        (457,620)          (663,722)
     Accumulated other comprehensive (loss) income .............................        (159,819)           264,388
     Accumulated deficit .......................................................     (83,677,667)       (66,511,442)
                                                                                    ------------       ------------
Total stockholders' equity .....................................................     102,977,864        120,019,863
                                                                                    ------------       ------------

                                                                                    $113,475,147       $133,444,785
                                                                                    ============       ============
</TABLE>




    The accompanying notes are an integral part of the financial statements.




                                      -3-
<PAGE>   4


                          GELTEX PHARMACEUTICALS, INC.

                       CONDENSED STATEMENTS OF OPERATIONS
                                   (UNAUDITED)

<TABLE>
<CAPTION>
                                                                               THREE MONTHS                  SIX MONTHS
                                                                              ENDED JUNE 30,                ENDED JUNE 30,
                                                                           1999           1998           1999            1998
                                                                       -----------    -----------    ------------    ------------
<S>                                                                    <C>            <C>            <C>             <C>
Revenue:
   Collaborative Joint Venture project reimbursement ...............   $ 1,078,682    $ 3,660,169    $  2,961,596    $  5,198,819
   Contract Revenue ................................................            --             --       1,751,670              --
                                                                       -----------    -----------    ------------    ------------
Total revenue ......................................................     1,078,682      3,660,169       4,713,266       5,198,819
Costs and expenses:
   Research and development ........................................     7,046,371      4,206,588      13,890,501      11,608,472
   Collaborative Joint Venture project costs .......................     1,078,682      3,660,169       2,961,596       5,198,819
                                                                       -----------    -----------    ------------    ------------
      Total research and development ...............................     8,125,053      7,866,757      16,852,097      16,807,291
   General and administrative ......................................     1,620,449      1,406,728       3,134,576       2,573,035
                                                                       -----------    -----------    ------------    ------------
Total costs and expenses ...........................................     9,745,502      9,273,485      19,986,673      19,380,326
                                                                       -----------    -----------    ------------    ------------

Loss from operations ...............................................    (8,666,820)    (5,613,316)    (15,273,407)    (14,181,507)

Interest income, net ...............................................     1,040,236      1,023,948       2,188,337       1,591,354
Equity in net loss of Joint Venture ................................    (1,789,299)    (2,028,881)     (4,067,864)     (2,924,553)
                                                                       -----------    -----------    ------------    ------------

Net loss ...........................................................   $(9,415,883)   $(6,618,249)   $(17,152,934)   $(15,514,706)
                                                                       ===========    ===========    ============    ============

Basic and diluted net loss per share ...............................   $     (0.56)   $     (0.40)   $      (1.02)   $      (0.97)
                                                                       ===========    ===========    ============    ============
Shares used in computing basic and diluted net loss per share ......    16,854,000     16,700,000      16,844,000      16,052,000
</TABLE>


    The accompanying notes are an integral part of the financial statements.



                                      -4-
<PAGE>   5





                          GELTEX PHARMACEUTICALS, INC.

                   CONDENSED STATEMENTS OF COMPREHENSIVE LOSS
                                   (UNAUDITED)

<TABLE>
<CAPTION>
                                                                                 THREE MONTHS                  SIX MONTHS
                                                                                ENDED JUNE 30,                ENDED JUNE 30,
                                                                             1999           1998           1999            1998
                                                                         -----------    -----------    ------------    ------------

<S>                                                                      <C>            <C>            <C>             <C>
Net loss .............................................................   $(9,415,883)   $(6,618,249)   $(17,152,934)   $(15,514,706)
Other Comprehensive Income (Loss):
    Unrealized gain (loss) on securities held during the period ......      (270,643)           248        (424,207)         19,820
                                                                         -----------    -----------    ------------    ------------
 Comprehensive loss ..................................................   $(9,686,526)   $(6,618,001)   $(17,577,141)   $(15,494,886)
                                                                         ===========    ===========    ============    ============
</TABLE>


    The accompanying notes are an integral part of the financial statements.



                                      -5-
<PAGE>   6



                          GELTEX PHARMACEUTICALS, INC.

                       CONDENSED STATEMENTS OF CASH FLOWS
                                   (UNAUDITED)

<TABLE>
<CAPTION>
                                                                                               SIX MONTHS
                                                                                              ENDED JUNE 30,
                                                                                         1999               1998
                                                                                     ------------      -------------

<S>                                                                                  <C>               <C>
OPERATING ACTIVITIES
Net loss .......................................................................     $(17,152,934)     $ (15,514,706)
Adjustments to reconcile net loss to net cash used in operating activities:
   Depreciation and amortization ...............................................          993,010            606,647
   Equity in net loss of Joint Venture .........................................        4,067,964          2,924,553
   Compensation from issuance of stock options .................................          375,738            304,771
   Changes in operating assets and liabilities:
        Prepaid expenses and other current assets ..............................         (112,824)        (1,075,545)
        Due from Joint Venture .................................................          683,445            (85,480)
        Long-term receivables ..................................................           31,134             (1,020)
        Accounts payable and accrued expenses ..................................         (398,433)        (3,357,556)
        Amount due to Joint Venture ............................................       (1,349,400)                --
        Inventory ..............................................................       (3,186,133)                --
                                                                                     ------------      -------------
Net cash used in operating activities ..........................................      (16,048,413)       (16,198,336)


INVESTING ACTIVITIES
Purchase of marketable securities ..............................................      (13,285,856)      (170,925,547)
Proceeds from sale and maturities of marketable securities .....................       16,098,566         96,473,671
Investment in Joint Venture ....................................................       (7,949,303)        (3,586,755)
Purchase of intangible assets ..................................................         (386,997)          (238,485)
Purchase of property and equipment, net ........................................         (650,726)          (869,408)
                                                                                     ------------      -------------
Net cash used in investing activities ..........................................       (6,174,316)       (79,146,524)

FINANCING ACTIVITIES
Sale of Common Stock and warrants, net of issuance costs .......................          342,331         77,136,262
Payments on long-term obligations ..............................................       (1,179,806)          (547,538)
                                                                                     ------------      -------------
Net cash provided by (used in) financing activities ............................         (837,475)        76,588,724
Decrease in cash and cash equivalents ..........................................      (23,060,204)       (18,756,136)
Cash and cash equivalents at beginning of period ...............................       30,874,900         26,689,190
                                                                                     ------------      -------------
Cash and cash equivalents at end of period .....................................        7,814,696      $   7,933,054
                                                                                     ============      =============

Interest paid ..................................................................     $    259,720      $     180,322
</TABLE>


    The accompanying notes are an integral part of the financial statements.



                                      -6-
<PAGE>   7

                          GELTEX PHARMACEUTICALS, INC.

                     NOTES TO CONDENSED FINANCIAL STATEMENTS
                                   (UNAUDITED)

1.    BASIS OF PRESENTATION

      The accompanying unaudited condensed financial statements for the three
and six months ended June 30, 1999 and 1998 have been prepared in accordance
with generally accepted accounting principles for interim financial information
and with the instructions to Form 10-Q and Article 10 of Regulation S-X.
Accordingly, they do not include all the information and notes required by
generally accepted accounting principles for complete financial statements. In
the opinion of management, the accompanying condensed financial statements
include all adjustments, consisting of normal recurring adjustments, necessary
for a fair presentation of the financial condition, results of operations and
cash flows for the periods presented. The results of operations for the interim
period ended June 30, 1999 are not necessarily indicative of the results to be
expected for the year ended December 31, 1999.

      These financial statements should be read in conjunction with the audited
financial statements and notes thereto for the fiscal year ended December 31,
1998 included in the Company's Annual Report on Form 10-K (File Number 0-26872)
as filed with the Securities and Exchange Commission.

2.    SUBSEQUENT EVENTS

      On July 30, 1999, the Company filed a New Drug Application ("NDA") with
the U.S. Food and Drug Administration for Cholestagel(R) (colesevelam
hydrochloride), for the treatment of hypercholesterolemia, a condition
characterized by undesirably high blood cholesterol levels.

      On August 16, 1999, the Company announced that it had entered into a
definitive agreement (the "Merger Agreement") to acquire SunPharm Corporation
("SunPharm"). Under the terms of the Merger Agreement, which was approved by
each company's board of directors, each share of SunPharm preferred stock
outstanding immediately prior to the effective time of the merger will be
automatically converted into between 0.18338 and 0.21740 shares of the Company's
common stock and each share of SunPharm common stock outstanding immediately
prior to the effective time of the merger will be automatically converted into
between 0.12225 and 0.14493 shares of the Company's common stock, in each case
subject to adjustment as set forth in the Merger Agreement. Based on the
Company's closing stock price of $14.25 on August 13, 1999, the transaction will
be valued at approximately $16.5 million. The transaction is subject to approval
by SunPharm shareholders as well as other customary requirements. The
transaction is expected to be completed during the last quarter of fiscal 1999,
and will be accounted for using the "purchase accounting" method.

3.    RECLASSIFICATION

      Certain amounts from the prior year have been reclassified to conform to
the current year presentation.

4.    JOINT VENTURE AGREEMENT

      In June 1997, the Company entered into a joint venture with Genzyme
Corporation for the final development and commercialization of Renagel(R)
Capsules (the "Joint Venture"). The Company accounts for its investment in the
Joint Venture using the equity method.

     Summarized financial information regarding the Joint Venture for the three
and six months ended June 30, 1999 is as follows:

                                                 THREE MONTHS       SIX MONTHS
                                                     ENDED             ENDED
                                                 JUNE 30, 1999     JUNE 30, 1999
                                                 -------------     -------------

        Net sales..............................  $  4,121,658       $ 7,667,623
        Cost of products sold..................     1,562,361         3,077,801
        Loss from operations...................    (3,894,588)       (9,647,806)
        Net loss...............................    (3,578,598)       (8,135,729)




                                      -7-
<PAGE>   8


ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
         OF OPERATIONS

RESULTS OF OPERATIONS

THREE AND SIX MONTHS ENDED JUNE 30, 1999 AND 1998

      The Company earned revenue of $1.1 million during the three months ended
June 30, 1999 compared with $3.7 million earned during the three months ended
June 30, 1998. During the six months ended June 30, 1999, revenues earned were
$4.7 million compared with $5.2 million earned during the six months ended June
30, 1998. Under the terms of the Collaboration Agreement the Company has entered
into with Genzyme Corporation ("Genzyme") for the commercialization of
Renagel(R) (the "Joint Venture"), the Company and Genzyme are each expected to
fund the Joint Venture in an amount equal to 50% of the budgeted costs and
expenses of the project for the relevant period. Each party that incurs project
expenses, either as internal operating costs or as third party obligations, will
be reimbursed by the Joint Venture for 100% of the costs incurred. In the three
month period ended June 30, 1999, all revenue earned by the Company represents
reimbursement from the Joint Venture for certain Renagel(R) development costs
incurred by the Company. For the six month period ended June 30, 1999, $1.7
million of the total revenue earned represents non-recurring reimbursement by
the Company's Japanese partner for certain Renagel(R) process development and
manufacturing costs incurred by the Company. The remaining $3.0 million of
revenue earned in the six month period ended June 30, 1999 represents
reimbursement from the Joint Venture for certain Renagel(R) development costs
incurred by the Company. All revenue earned in the three and six month periods
ended June 30, 1998 represents reimbursement from the Joint Venture for certain
Renagel(R) development costs incurred by the Company. The amount of
reimbursement revenue earned by the Company will vary according to the
obligations of, and related expense incurred, by the Company, and is expected to
continue to decrease as the Company completes the development activities for the
Joint Venture.

      The Company's total operating expenses for the three months ended June 30,
1999 increased by $0.4 million to $9.7 million from $9.3 million during the same
period in 1998. The Company's total operating expenses were $20.0 million and
$19.4 million for the six months ended June 30, 1999 and 1998, respectively.
Research and development expenses increased by $0.2 million to $8.1 million for
the three month period ended June 30, 1999 from $7.9 million for the period
ended June 30, 1998. For the six months ended June 30, 1999 and 1998, research
and development expenses were $16.8 million. The relatively flat research and
development expense is due to the decrease in the development activities for the
Joint Venture offset by an increase in the costs associated with the Company's
other research programs. The Company expects its research and development
expenses to increase in connection with the continuing development of processes
for the manufacture of commercial quantities of Cholestagel, the expansion of
the anti-obesity, infectious diseases and other research and development
programs, and with the research and development activities associated with the
SunPharm acquisition. General and administrative expenses increased $0.2 million
to $1.6 million for the three months ended June 30, 1999 from $1.4 million for
the same period a year ago. During the six month period ended June 30, 1999,
general and administrative expenses increased to $3.1 million from $2.6 million
during the same period in 1998. The increase was due primarily to increased
business development and increased administrative personnel costs.

      The Company's equity in the net loss of the Joint Venture with Genzyme
Corporation was $1.8 million and $2.0 million for the three month periods ended
June 30, 1999 and 1998, respectively. For the six month periods ended June 30,
1999 and 1998, the Company's equity in the net loss of the Joint Venture was
$4.1 million and $2.9 million, respectively. These costs represent the Company's
portion of the Joint Venture loss for the relevant periods and reflect the
increased costs associated with the commercial launch of Renagel(R). The Company
expects that the Joint Venture will continue to operate at a loss at least into
2000.

      Net interest income remained constant at $1.0 million for the three months
ended June 30, 1999 and 1998. For the six month period ended June 30, 1999 and
1998, net interest income was $2.2 million and $1.6 million, respectively. The
increase was due primarily to net higher average cash balances during the six
month period in 1999.

LIQUIDITY AND CAPITAL RESOURCES

      As of June 30, 1999, the Company had $78 million in cash, cash equivalents
and marketable securities as compared to $105 million at December 31, 1998. The
Company believes that its existing cash balances and marketable securities will
be sufficient to fund its operations through at least 2001.

      On October 21, 1998, the Company entered into a synthetic lease
transaction under which the lessor has committed to fund up to an aggregate of
$25.0 million for the purchase of a new building to serve as the Company's new
headquarters and for the costs




                                      -8-
<PAGE>   9

associated with the build-out of this facility. The synthetic lease is
asset-based financing structured to be treated as an operating lease for
accounting purposes. The Company is serving as construction agent for the
lessor. At June 30, 1999, the lessor's total accumulated cost for the land and
the partial build-out of the facility was approximately $15.3 million. Under the
terms of the synthetic lease, the Company is required to comply with certain
financial covenants which, among other things, require the maintenance of
minimum levels of cash, tangible net worth, liquidity and debt service coverage
and prohibits the payment of dividends. The Company was in compliance with these
terms at June 30, 1999.

      In August 1999, the Company entered into a Purchase and Sale Agreement to
acquire a building and land adjacent to the Company's new headquarters. The
purchase, which is contingent upon the favorable outcome of certain due
diligence to be conducted by the Company throughout the month of August is
expected to close in the third quarter of 1999. The Company expects to secure
financing sufficient to fund $3.0 million of the $3.2 million purchase price
through an amendment to its existing long-term debt agreement.

      The Company is in negotiations with a financial institution to establish a
$5.0 million lease line to finance the cost of equipment purchases. It is
expected that the line will be drawn down for purchases and will be repaid in 48
equal monthly installments commencing in July 2000.

      The Company has agreed in principle to the terms of a manufacturing
agreement with its contract manufacturer for the production of bulk inventory
for Cholestagel. The Company will be obligated under the terms of the agreement
to pay approximately 352.1 million Austrian schillings (approximately $27.6
million as of June 30, 1999) through 2000. The Company is proceeding with
payments to the manufacturer, and as of June 30, 1999 has paid approximately
$3.1 million.

YEAR 2000

      The Year 2000 problem is a result of software programs being written using
two digits rather than four to define the applicable year. The Company
recognizes the risk that its information technology ("IT") systems and other
systems such as telephones, building access control systems and heating and
ventilation equipment ("embedded systems") may have date-sensitive software or
embedded chips that may recognize a date using "00" as the year 1900 rather than
the year 2000. This error could result in system failure or miscalculations
causing disruptions to the Company's research and development, financial,
administration and communication operations. The Company also has business
relationships with third parties that are themselves reliant on IT and embedded
systems to conduct their businesses. The Company recognizes the need to ensure
its operations will not be adversely impacted by Year 2000 software and hardware
failure both internally and from third parties with which the Company has an
important relationship.

      In 1998, the Company developed a plan to ensure that its systems would be
Year 2000 compliant. The plan consists of four phases: (1)
assessment--identifying all IT systems that use date functions and assessing
Year 2000 functionality and compliance, (2) remediation-- reprogramming or
replacing inventoried items to ensure Year 2000 compliance, (3) testing--
testing the code modifications or new inventory with other associated systems,
including date testing and quality assurance to ensure successful operation in
the post-1999 environment, and (4) implementation--returning all remediated and
successfully tested items back into normal operation. This plan encompasses IT
and embedded systems, as well as third party exposure.

The Company's State of Readiness

    As of December 31, 1998, the Company had completed all four phases of the
plan for its IT systems and has concluded that its IT systems are Year 2000
compliant. The assessment phase for the embedded systems is complete. The
assessment indicated that certain embedded systems are not Year 2000 compliant.
The Company will complete the remaining three phases of testing for these
non-compliant embedded systems by December 1999. The cost of remediating these
non-compliant embedded systems will be approximately $100,000 and will be funded
from available cash.

Third Parties and Their Exposure to Year 2000

    The Company has continued formal communications with all significant third
parties, primarily, clinical trial sites, contract research organizations and
contract manufacturers. The Company has requested and has received from a
majority of these third parties, written statements regarding their knowledge of
and plans for being Year 2000 compliant. The Company has one direct system
interface with a third party and has received verification that the system
interface is Year 2000 compliant.




                                      -9-
<PAGE>   10




Contingency Plans

    The Company has not yet developed a comprehensive contingency plan to
address situations that may result if the Company or any of the third parties
upon which the Company is dependent are unable to achieve Year 2000 readiness.
However, the Company's Year 2000 compliance program is ongoing and its scope,
including the development of contingency plans for the most reasonably likely
worst case scenario, will continue to be evaluated.

Risks

    The Company's management believes it has an effective plan in place to
mitigate the risks of the Year 2000 issue in a timely manner. However, as noted
above, the Company has not yet completed all necessary phases of its Year 2000
plan. In the event that the Company is not able to complete the necessary
phases, the Company could experience business interruptions. In addition, the
inability of a third party upon which the Company is dependent to complete its
Year 2000 compliance program in a timely manner, as well as disruptions in the
general economy resulting from the Year 2000 issue could have a material adverse
impact on the Company's results of operations, liquidity or financial position.

ITEM 3.    QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

    Market risks were reported in the Notes to the Financial Statements for the
Company's Annual Report on Form 10-K for the year ended December 31, 1998. There
have been no material changes in these risks since the end of the year.




                                      -10-
<PAGE>   11



                           PART II. OTHER INFORMATION

ITEM 4.    SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

    The Company's 1999 Annual Meeting of Stockholders was held May 27, 1999. The
following is a description of the three matters submitted to a vote of the
stockholders at such meeting and the results of voting.

    (i)   At the meeting a director was elected to serve on the Company's Board
          of Directors.

                                              Number of Shares
                            Number of Shares    Voted Against       Number of
          Director Elected     Voted For         Or Withheld    Shares Abstained
        ------------------  ----------------  ----------------  ----------------
        Robert J. Carpenter    12,879,601           219,470          10,177

    There were no broker non-votes with respect to this matter.

    The following directors' terms of office as directors continued after the
meeting: Mark Skaletsky, J. Richard Crout, Henri Termeer and Jesse Treu.

    (ii)  The Stockholders also approved an amendment to the Company's 1992
          Equity Incentive Plan to increase the number of shares of Common
          Stock reserved under such plan from 2,750,000 to 3,350,000.

                Number of Shares Voted For:                          12,424,418
                Number of Shares Voted Against or Withheld:             664,476
                Number of Shares Abstained:                              10,177

    There were no broker non-votes with respect to this matter.

    (iii) The Stockholders also approved an amendment to the Company's 1995
          Director Stock Option Plan to increase the number of shares of Common
          Stock reserved for issuance under this Plan from 110,000 to 150,000.

                Number of Shares Voted For:                          12,935,568
                Number of Shares Voted Against or Withheld:             152,666
                Number of Shares Abstained:                              10,837

    There were no broker non-votes with respect to this matter.

ITEM 5.    OTHER INFORMATION

    On August 16, 1999, the Company announced that it had entered into a
definitive agreement (the "Merger Agreement") to acquire SunPharm Corporation
("SunPharm"), a development stage biotechnology company. SunPharm is focused on
the development of small molecule pharmaceutical products, consisting of novel
polyamine analogue and metal chelator compounds. SunPharm's drug development
efforts are focused on cancer, refractory diarrhea associated with acquired
immunodeficiency syndrome, other gastrointestinal disorders, and iron overload.

    Under the terms of the Merger Agreement, which was approved by each
company's board of directors, each share of SunPharm preferred stock outstanding
immediately prior to the effective time of the merger will be automatically
converted into between 0.18338 and 0.21740 shares of the Company's common stock
and each share of SunPharm common stock outstanding immediately prior to the
effective time of the merger will be automatically converted into between
0.12225 and 0.14493 shares of the Company's common stock, in each case subject
to adjustment as set forth in the Merger Agreement. Based on the Company's
closing stock price of $14.25 on August 13, 1999, the transaction will be
valued at approximately $16.5 million. The transaction is subject to approval by
SunPharm shareholders as well as other customary requirements. The transaction
is expected to be completed during the last quarter of fiscal 1999, and will be
accounted for using the "purchase accounting" method. Attached and incorporated
herein by reference in its entirety as Exhibit 10.3 is a copy of the Merger
Agreement.



                                      -11-
<PAGE>   12

ITEM 6.    EXHIBITS AND REPORTS ON FORM 8-K.

           (a)   Exhibits.

                 See the Exhibit Index on page 14 hereto.

           (b)   Reports on Form 8-K.

                 None.




                                      -12-
<PAGE>   13




                          GELTEX PHARMACEUTICALS, INC.
                                    FORM 10-Q

                                  JUNE 30, 1999

                                    SIGNATURE

     Pursuant to the requirements of the Securities Exchange Act of 1934, as
amended, the registrant has duly caused this report to be signed on its behalf
by the undersigned thereunto duly authorized.


                                             GELTEX PHARMACEUTICALS, INC.

DATE: August 16, 1999                         BY: /s/ Paul J. Mellett, Jr.
                                                 -------------------------------
                                                 Paul J. Mellett, Jr.
                                                 Duly Authorized  Officer and
                                                 Principal Financial Officer







                                      -13-
<PAGE>   14







                                  EXHIBIT INDEX



EXHIBIT NUMBER                     DESCRIPTION
- --------------                     -----------

     10.1#         Amended and restated 1992 Equity Incentive Plan.

     10.2#         Amended and restated 1995 Director Stock Option Plan.

     10.3*         Agreement and Plan of Merger dated as of August 13, 1999
                   among GelTex Pharmaceuticals, Inc., SunPharm Corporation, and
                   Shine Acquisition Sub., Inc.

     10.4          Purchase and Sale Agreement between Barry L. Solar and Robert
                   L. Solar as Trustees of 211 Second Avenue Realty Trust and
                   the Company dated as of July 26, 1999.

     27.1          Financial Data Schedule

- ------------------


# Identifies a management contract or compensatory plan or arrangement in which
  an executive officer or director of the Company participates.

* Pursuant to Item 601(b)(2) of Regulation S-K, the Schedules to the Merger
  Agreement are omitted. A list of such schedules appears in the Merger
  Agreement. The Company hereby undertakes to furnish supplementally a copy
  of any omitted schedule to the Commission upon request.








                                      -14-





<PAGE>   1
                                                                    Exhibit 10.1

                          GELTEX PHARMACEUTICALS, INC.

                 AMENDED AND RESTATED 1992 EQUITY INCENTIVE PLAN

Section 1.  PURPOSE

           The purpose of the GelTex Pharmaceuticals, Inc. 1992 Equity Incentive
Plan (the "Plan") is to attract and retain key employees and consultants, to
provide an incentive for them to achieve long-range performance goals, and to
enable them to participate in the long-term growth of the Company.

Section 2.  DEFINITIONS

           "Affiliate" means any business entity in which the Company owns
directly or indirectly 50% or more of the total combined voting power or has a
significant financial interest as determined by the Committee.

           "Award" means any Option, Stock Appreciation Right, Performance
Share, Restricted Stock, Stock Unit or Other Stock-Based Award awarded under the
Plan.

           "Board" means the Board of Directors of the Company.

           "Code" means the Internal Revenue Code of 1986, as amended from time
to time, and any successor to such Code.

           "Committee" means a committee of not less than two members of the
Board appointed by the Board to administer the Plan; provided, however, that
until such committee is appointed, "Committee" means the Board.

           "Common Stock" or "Stock" means the Common Stock, $0.01 par value, of
the Company.

           "Company" means GelTex Pharmaceuticals, Inc.

           "Designated Beneficiary" means the beneficiary designated by a
Participant, in a manner determined by the Committee, to receive amounts due or
exercise rights of the Participant in the event of the Participant's death. In
the absence of an effective designation by a Participant, "Designated
Beneficiary" shall mean the Participant's estate.

           "Effective Date" means June 1, 1992.

           "Fair Market Value" means, with respect to Common Stock or any other
property, the fair market value of such property as determined by the Committee
in good faith or in the manner established by the Committee from time to time.

           "Incentive Stock Option" means an option to purchase shares of Common
Stock awarded to a




<PAGE>   2

Participant under Section 6 that is intended to meet the requirements of Section
422 of the Code or any successor provision.

           "Nonstatutory Stock Option" means an option to purchase shares of
Common Stock awarded to a Participant under Section 6 that is not intended to be
an Incentive Stock Option.

           "Option" means an Incentive Stock Option or a Nonstatutory Stock
Option.

           "Other Stock-Based Award" means an Award, other than an Option, Stock
Appreciation Right, Performance Share, Restricted Stock or Stock Unit, having a
Common Stock element and awarded to a Participant under Section 11.

           "Participant" means a person selected by the Committee to receive an
Award under the Plan.

           "Performance Cycle" or "Cycle" means the period of time selected by
the Committee during which performance is measured for the purpose of
determining the extent to which an award of Performance Shares has been earned.

           "Performance Shares" mean shares of Common Stock, which may be earned
by the achievement of performance goals, awarded to a Participant under Section
8.

           "Reporting Person" means a person subject to Section 16 of the
Securities Exchange Act of 1934 or any successor provision.

           "Restricted Period" means the period of time during which an Award
may be forfeited to the Company pursuant to the terms and conditions of such
Award.

           "Restricted Stock" means shares of Common Stock subject to forfeiture
awarded to a Participant under Section 9.

           "Stock Appreciation Right" or "SAR" means a right to receive any
excess in value of shares of Common Stock over the exercise price awarded to a
Participant under Section 7.

           "Stock Unit" means an award of Common Stock or units that are valued
in whole or in part by reference to, or otherwise based on, the value of Common
Stock, awarded to a Participant under Section 10.

Section 3.  ADMINISTRATION

           The Plan shall be administered by the Committee; provided, however,
that any duties described herein as duties of the Committee may at all times be
conducted by the Board of Directors as a whole, in its discretion. The Committee
shall have authority to adopt, alter and repeal such administrative rules,
guidelines and practices governing the operation of the Plan as it shall from
time to time consider advisable, and to interpret the provisions of the Plan.
The Committee's decisions shall be final and binding. To the extent permitted by
applicable law, the Committee may delegate to one or more executive officers of
the Company the power to make Awards to Participants who are not Reporting




                                       2
<PAGE>   3

Persons and all determinations under the Plan with respect thereto, provided
that the Committee shall fix the maximum amount of such Awards for the group and
a maximum for any one Participant.

Section 4.  ELIGIBILITY

           All employees and, in the case of Awards other than Incentive Stock
Options, consultants and members of the Board of Directors of the Company or any
Affiliate capable of contributing significantly to the successful performance of
the Company, other than a person who has irrevocably elected not to be eligible,
are eligible to be Participants in the Plan. Incentive Stock Options may be
awarded only to persons eligible to receive such Options under the Code.

Section 5.  STOCK AVAILABLE FOR AWARDS

           (a) Subject to adjustment under subsection (c), Awards may be made
under the Plan for up to 3,350,000 shares of Common Stock If any Award in
respect of shares of Common Stock expires or is terminated unexercised or is
forfeited without the Participant having had the benefits of ownership (other
than voting rights), the shares subject to such Award, to the extent of such
expiration, termination or forfeiture, shall again be available for award under
the Plan. Common Stock issued through the assumption or substitution of
outstanding grants from an acquired company shall not reduce the shares
available for Awards under the Plan. Shares issued under the Plan may consist in
whole or in part of authorized but unissued shares or treasury shares.

           (b) Subject to adjustment under subsection (c), no Participant may
receive an Award which would result in such Participant having received, during
the fiscal year of the Company in which the Award is made, Awards for more than
an aggregate of 250,000 shares of Common Stock.

           (c) In the event that the Committee in its discretion determines that
any stock dividend, extraordinary cash dividend, creation of a class of equity
securities, recapitalization, reorganization, merger, consolidation, split-up,
spin-off, combination, exchange of shares, warrants or rights offering to
purchase Common Stock at a price substantially below fair market value, or other
similar transaction affects the Common Stock such that an adjustment is required
in order to preserve the benefits or potential benefits intended to be made
available under the Plan, then the Committee (subject, in the case of Incentive
Stock Options, to any limitation required under the Code) shall equitably adjust
any or all of (i) the number and kind of shares in respect of which Awards may
be made under the Plan, (ii) the number and kind of shares subject to
outstanding Awards, and (iii) the award, exercise or conversion price with
respect to any of the foregoing, and if considered appropriate, the Committee
may make provision for a cash payment with respect to an outstanding Award,
provided that the number of shares subject to any Award shall always be a whole
number.

Section 6.  STOCK OPTIONS

           (a) Subject to the provisions of the Plan, the Committee may award
Incentive Stock Options and Nonstatutory Stock Options and determine the number
of shares to be covered by each Option, the option price therefor and the
conditions and limitations applicable to the exercise of the Option. The terms
and conditions of Incentive Stock Options shall be subject to and comply with
Section 422 of the Code, or any successor provision, and any regulations
thereunder, and no Incentive


                                       3
<PAGE>   4

Stock Option may be granted hereunder more than ten years after the Effective
Date.

           (b) The Committee shall establish the option price at the time each
Option is awarded, which price shall not be less than 100% of the Fair Market
Value of the Common Stock on the date of award with respect to Incentive Stock
Options. Nonstatutory Stock Options may be granted at such prices as the
Committee may determine.

           (c) Each Option shall be exercisable at such times and subject to
such terms and conditions as the Committee may specify in the applicable Award
or thereafter. The Committee may impose such conditions with respect to the
exercise of Options, including conditions relating to applicable federal or
state securities laws, as it considers necessary or advisable.

           (d) No shares shall be delivered pursuant to any exercise of an
Option until payment in full of the option price therefor is received by the
Company. Such payment may be made in whole or in part in cash or, to the extent
permitted by the Committee at or after the award of the Option, by delivery of a
note or shares of Common Stock owned by the optionee, including Restricted
Stock, valued at their Fair Market Value on the date of delivery, or such other
lawful consideration as the Committee may determine.

           (e) The Committee may provide that, subject to such conditions as it
considers appropriate, upon the delivery of shares to the Company in payment of
an Option, the Participant shall automatically be awarded an Option for up to
the number of shares so delivered.

Section 7.  STOCK APPRECIATION RIGHTS

           (a) Subject to the provisions of the Plan, the Committee may award
SARs in tandem with an Option (at or after the award of the Option), or alone
and unrelated to an Option. SARs in tandem with an Option shall terminate to the
extent that the related Option is exercised, and the related Option shall
terminate to the extent that the tandem SARs are exercised. SARs granted in
tandem with Options shall have an exercise price not less than the exercise
price of the related Option. SARs granted alone and unrelated to an Option may
be granted at such exercise prices as the Committee may determine.

           (b) An SAR related to an Option that can only be exercised during
limited periods following a change in control of the Company may entitle the
Participant to receive an amount based upon the highest price paid or offered
for Common Stock in any transaction relating to the change in control or paid
during the thirty-day period immediately preceding the occurrence of the change
in control in any transaction reported in the stock market in which the Common
Stock is normally traded.

Section 8.  PERFORMANCE SHARES

           (a) Subject to the provisions of the Plan, the Committee may award
Performance Shares and determine the number of such shares for each Performance
Cycle and the duration of each Performance Cycle. There may be more than one
Performance Cycle in existence at any one time, and the duration of Performance
Cycles may differ from each other. The payment value of Performance Shares shall
be equal to the Fair Market Value of the Common Stock on the date the
Performance



                                       4
<PAGE>   5

Shares are earned or, in the discretion of the Committee, on the date the
Committee determines that the Performance Shares have been earned.

           (b) The Committee shall establish performance goals for each Cycle,
for the purpose of determining the extent to which Performance Shares awarded
for such Cycle are earned, on the basis of such criteria and to accomplish such
objectives as the Committee may from time to time select. During any Cycle, the
Committee may adjust the performance goals for such Cycle as it deems equitable
in recognition of unusual or non-recurring events affecting the Company, changes
in applicable tax laws or accounting principles, or such other factors as the
Committee may determine.

           (c) As soon as practicable after the end of a Performance Cycle, the
Committee shall determine the number of Performance Shares that have been earned
on the basis of performance in relation to the established performance goals.
The payment values of earned Performance Shares shall be distributed to the
Participant or, if the Participant has died, to the Participant's Designated
Beneficiary, as soon as practicable thereafter. The Committee shall determine,
at or after the time of award, whether payment values will be settled in whole
or in part in cash or other property, including Common Stock or Awards.

Section 9.  RESTRICTED STOCK

           (a) Subject to the provisions of the Plan, the Committee may award
shares of Restricted Stock and determine the duration of the Restricted Period
during which, and the conditions under which, the shares may be forfeited to the
Company and the other terms and conditions of such Awards. Shares of Restricted
Stock shall be issued for no cash consideration or such minimum consideration as
may be required by applicable law.

           (b) Shares of Restricted Stock may not be sold, assigned,
transferred, pledged or otherwise encumbered, except as permitted by the
Committee, during the Restricted Period. Shares of Restricted Stock shall be
evidenced in such manner as the Committee may determine. Any certificates issued
in respect of shares of Restricted Stock shall be registered in the name of the
Participant and unless otherwise determined by the Committee, deposited by the
Participant, together with a stock power endorsed in blank, with the Company. At
the expiration of the Restricted Period, the Company shall deliver such
certificates to the Participant or if the Participant has died, to the
Participant's Designated Beneficiary.

Section 10.  STOCK UNITS

           (a) Subject to the provisions of the Plan, the Committee may award
Stock Units subject to such terms, restrictions, conditions, performance
criteria, vesting requirements and payment rules as the Committee shall
determine.

           (b) Shares of Common Stock awarded in connection with a Stock Unit
Award shall be issued for no cash consideration or such minimum consideration as
may be required by applicable law.



                                       5
<PAGE>   6

Section 11.  OTHER STOCK-BASED AWARDS

           (a) Subject to the provisions of the Plan, the Committee may make
other awards of Common Stock and other awards that are valued in whole or in
part by reference to, or are otherwise based on, Common Stock, including
without limitation convertible preferred stock, convertible debentures,
exchangeable securities and Common Stock awards or options. Other Stock-Based
Awards may be granted either alone or in tandem with other Awards granted under
the Plan and/or cash awards made outside of the Plan.

           (b) The Committee may establish performance goals, which may be based
on performance goals related to book value, subsidiary performance or such other
criteria as the Committee may determine, Restricted Periods, Performance Cycles,
conversion prices, maturities and security, if any, for any Other Stock-Based
Award. Other Stock-Based Awards may be sold to Participants at the face value
thereof or any discount therefrom or awarded for no consideration or such
minimum consideration as may be required by applicable law.

Section 12.  GENERAL PROVISIONS APPLICABLE TO AWARDS

           (a) Reporting Person Limitations. Notwithstanding any other provision
of the Plan, to the extent required to qualify for the exemption provided by
Rule 16b-3 under the Securities Exchange Act of 1934 and any successor
provision, Awards made to a Reporting Person shall not be transferable by such
person other than by will or the laws of descent and distribution or pursuant to
a qualified domestic relations order, as defined in the Code or Title I of the
Employee Retirement Income Security Act, or the rules thereunder.

           (b) Documentation. Each Award under the Plan shall be evidenced by a
writing delivered to the Participant specifying the terms and conditions thereof
and containing such other terms and conditions not inconsistent with the
provisions of the Plan as the Committee considers necessary or advisable to
achieve the purposes of the Plan or comply with applicable tax and regulatory
laws and accounting principles.

           (c) Committee Discretion. Each type of Award may be made alone, in
addition to or in relation to any other type of Award. The terms of each type of
Award need not be identical, and the Committee need not treat Participants
uniformly. Except as otherwise provided by the Plan or a particular Award, any
determination with respect to an Award may be made by the Committee at the time
of award or at any time thereafter.

           (d) Settlement. The Committee shall determine whether Awards are
settled in whole or in part in cash, Common Stock, other securities of the
Company, Awards or other property. The Committee may permit a Participant to
defer all or any portion of a payment under the Plan, including the crediting of
interest on deferred amounts denominated in cash and dividend equivalents on
amounts denominated in Common Stock.

           (e) Dividends and Cash Awards. In the discretion of the Committee,
any Award under the Plan may provide the Participant with (i) dividends or
dividend equivalents payable currently or deferred with or without interest, and
(ii) cash payments in lieu of or in addition to an Award.



                                       6
<PAGE>   7

           (f) Termination of Employment. The Committee shall determine the
effect on an Award of the disability, death, retirement or other termination of
employment of a Participant and the extent to which, and the period during
which, the Participant's legal representative, guardian or Designated
Beneficiary may receive payment of an Award or exercise rights thereunder.

           (g) Change in Control. In order to preserve a Participant's rights
under an Award in the event of a change in control of the Company, the Committee
in its discretion may, at the time an Award is made or at any time thereafter,
take one or more of the following actions: (i) provide for the acceleration of
any time period relating to the exercise or realization of the Award, (ii)
provide for the purchase of the Award upon the Participant's request for an
amount of cash or other property that could have been received upon the exercise
or realization of the Award had the Award been currently exercisable or payable,
(iii) adjust the terms of the Award in a manner determined by the Committee to
reflect the change in control, (iv) cause the Award to be assumed, or new rights
substituted therefor, by another entity, or (v) make such other provision as the
Committee may consider equitable and in the best interests of the Company.

           (h) Loans. The Committee may authorize the making of loans or cash
payments to Participants in connection with any Award under the Plan, which
loans may be secured by any security, including Common Stock, underlying or
related to such Award (provided that such Loan shall not exceed the Fair Market
Value of the security subject to such Award), and which may be forgiven upon
such terms and conditions as the Committee may establish at the time of such
loan or at any time thereafter.

           (i) Withholding. The Participant shall pay to the Company, or make
provision satisfactory to the Committee for payment of, any taxes required by
law to be withheld in respect of Awards under the Plan no later than the date of
the event creating the tax liability. In the Committee's discretion, such tax
obligations may be paid in whole or in part in shares of Common Stock, including
shares retained from the Award creating the tax obligation, valued at their Fair
Market Value on the date of delivery. The Company and its Affiliates may, to the
extent permitted by law, deduct any such tax obligations from any payment of any
kind otherwise due to the Participant.

           (j) Foreign Nationals. Awards may be made to Participants who are
foreign nationals or employed outside the United States on such terms and
conditions different from those specified in the Plan as the Committee considers
necessary or advisable to achieve the purposes of the Plan or comply with
applicable laws.

           (k) Amendment of Award. The Committee may amend, modify or terminate
any outstanding Award, including substituting therefor another Award of the same
or a different type, changing the date of exercise or realization and converting
an Incentive Stock Option to a Nonstatutory Stock Option, provided that the
Participant's consent to such action shall be required unless the Committee
determines that the action, taking into account any related action, would not
materially and adversely affect the Participant.



                                       7
<PAGE>   8

Section 13.  MISCELLANEOUS

           (a) No Right To Employment. No person shall have any claim or right
to be granted an Award, and the grant of an Award shall not be construed as
giving a Participant the right to continued employment. The Company expressly
reserves the right at any time to dismiss a Participant free from any liability
or claim under the Plan, except as expressly provided in the applicable Award.

           (b) No Rights As Shareholder. Subject to the provisions of the
applicable Award, no Participant or Designated Beneficiary shall have any rights
as a shareholder with respect to any shares of Common Stock to be distributed
under the Plan until he or she becomes the holder thereof. A Participant to whom
Common Stock is awarded shall be considered the holder of the Stock at the time
of the Award except as otherwise provided in the applicable Award.

           (c) Effective Date. Subject to the approval of the shareholders of
the Company, the Plan shall be effective on the Effective Date. Prior to such
approval, Awards may be made under the Plan expressly subject to such approval.

           (d) Amendment of Plan. The Board may amend, suspend or terminate the
Plan or any portion thereof at any time, subject to any shareholder approval
that the Board determines to be necessary or advisable.

           (e) Governing Law. The provisions of the Plan shall be governed by
and interpreted in accordance with the laws of Delaware.




                                       8

<PAGE>   1
                                                                    Exhibit 10.2

                          GELTEX PHARMACEUTICALS, INC.

              AMENDED AND RESTATED 1995 DIRECTOR STOCK OPTION PLAN

           The purpose of this 1995 Director Stock Option Plan (the "Plan") of
GelTex Pharmaceuticals, Inc. (the "Company") is to attract and retain highly
qualified non-employee directors of the Company and to encourage ownership of
stock of the Company by such Directors so as to provide additional incentives to
promote the success of the Company.

1.  ADMINISTRATION OF THE PLAN.

           Grants of stock options under the Plan shall be automatic as provided
in Section 6. However, all questions of interpretation with respect to the Plan
and options granted under it shall be determined by the Board of Directors of
the Company (the "Board") or by a committee consisting of one or more directors
appointed by the Board and such determination shall be final and binding upon
all persons having an interest in the Plan.

2.  PERSONS ELIGIBLE TO PARTICIPATE IN THE PLAN.

           Each director of the Company who is not an employee of the Company or
of any subsidiary of the Company shall be eligible to participate in the Plan
unless such director irrevocably elects not to participate.

3.  SHARES SUBJECT TO THE PLAN.

           (a) The aggregate number of shares of the Company's Common Stock
which may be optioned under this Plan is 150,000 shares. Shares issued under the
Plan may consist in whole or in part of authorized but unissued shares or
treasury shares.

           (b) In the event of a stock dividend, split-up, combination or
reclassification of shares, recapitalization or other similar capital change
relating to the Company's Common Stock, the maximum aggregate number and kind of
shares or securities of the Company as to which options may be granted under
this Plan and as to which options then outstanding shall be exercisable, and the
option price of such options shall be appropriately adjusted so that the
proportionate number of shares or other securities as to which options may be
granted and the proportionate interest of holders of outstanding options shall
be maintained as before the occurrence of such event.

           (c) In the event of a consolidation or merger of the Company with
another corporation where the Company's stockholders do not own a majority in
interest of the surviving or resulting corporation, or the sale or exchange of
all or substantially all of the assets of the Company, or a reorganization or
liquidation of the Company, any deferred exercise period shall be automatically
accelerated and each holder of an outstanding option shall be entitled to
receive upon exercise and payment in accordance with the terms of the option the
same shares, securities or property as he







<PAGE>   2

would have been entitled to receive upon the occurrence of such event if he had
been, immediately prior to such event, the holder of the number of shares of
Common Stock purchasable under his or her option; provided, however, that in
lieu of the foregoing the Board may upon written notice to each holder of an
outstanding option or right under the Plan, provide that such option or right
shall terminate on a date not less than 20 days after the date of such notice
unless theretofore exercised.

           (d) Whenever options under this Plan lapse or terminate or otherwise
become unexercisable the shares of Common Stock which were subject to such
options may again be subjected to options under this Plan. The Company shall at
all times while this Plan is in force reserve such number of shares of Common
Stock as will be sufficient to satisfy the requirements of this Plan.

4.  NON-STATUTORY STOCK OPTIONS.

           All options granted under this Plan shall be non-statutory options
not entitled to special tax treatment under Section 422 of the Internal Revenue
Code of 1986, as amended (the "Code").

5.  FORM OF OPTIONS.

           Options granted hereunder shall be in substantially the form as the
Board or any committee appointed pursuant to Section 1 above may from time to
time determine.

6.  GRANT OF OPTIONS AND OPTION TERMS.

           (a) AUTOMATIC GRANT OF OPTIONS. Upon the adoption of this Plan by the
Board of Directors each eligible director shall automatically be granted options
to purchase 4,000 shares of Common Stock for each year of the term of office for
which such director has been nominated to stand for election at the Company's
1996 annual meeting of stockholders, such that Class I Directors shall be
granted options to purchase 12,000 shares; Class II Directors shall be granted
options to purchase 8,000 shares and Class III Directors shall be granted
options to purchase 4,000 shares. Upon the election or re-election of any
eligible director at the Company's 1997 annual meeting of its stockholders and
upon each annual meeting of the stockholders thereafter, each such director
shall automatically be granted options to purchase 4,000 shares of Common Stock
for each year of the term of office to which he or she is elected. In addition,
upon the election of a director who is eligible to receive options to purchase
Common Stock under the Plan other than at an annual meeting of stockholders
(whether by the Board or the stockholders and whether to fill a vacancy or
otherwise), such director shall automatically be granted options to purchase
4,000 shares of Common Stock for each year or portion thereof of the term of
office to which he or she is elected. No options shall be granted hereunder
after ten years from the date on which this Plan was initially approved and
adopted by the Board.

           (b) DATE OF GRANT. The "Date of Grant" for options granted under this
Plan shall be the




                                       2
<PAGE>   3

date of adoption of the Plan, or the date of election or re-election as a
director, as the case may be.

           (c) OPTION PRICE. The option price for each option granted under this
Plan shall be the current fair market value of a share of Common Stock of the
Company as determined by the closing price for the Company's Common Stock as
reported by the National Association of Securities Dealers Automated Quotations
National Market System on the Date of Grant.

           (d) TERM OF OPTION. The term of each option granted under this Plan
shall be ten years from the Date of Grant.

           (e) EXERCISABILITY OF OPTIONS. Options granted upon the adoption of
this Plan shall become exercisable with respect to 4,000 shares on the date of
the Company's 1997 annual meeting of stockholders and on each of the next two
annual meetings of stockholders of the Company following such annual meeting of
stockholders (i.e., options to purchase 12,000 shares of Common Stock granted
upon the adoption of the Plan will become exercisable with respect to 4,000
shares at each of the 1997, 1998 and 1999 annual meetings). Otherwise, Options
granted under this Plan shall become exercisable with respect to 4,000 shares on
the each of the first three annual meetings of stockholders of the Company
following the Date of Grant, but in all cases if and only if the option holder
is a member of the Board at the opening of business on that date.

           (f) GENERAL EXERCISE TERMS. Directors holding exercisable options
under this Plan who cease to serve as members of the Board may, during their
lifetime, exercise the rights they had under such options at the time they
ceased being a director for the full unexpired term of such option. Any rights
that have not yet become exercisable shall terminate upon cessation of
membership on the Board. Upon the death of a director, those entitled to do so
shall have the right, at any time within twelve months after the date of death,
to exercise in whole or in part any rights which were available to the director
at the time of his or her death. The rights of the option holder may be
exercised by the holder's guardian or legal representative in the case of
disability and by the beneficiary designated by the holder in writing delivered
to the Company or, if none has been designated, by the holder's estate or his or
her transferee on death in accordance with this Plan, in the case of death.
Options granted under the Plan shall terminate, and no rights thereunder may be
exercised, after the expiration of the applicable exercise period.
Notwithstanding the foregoing provisions of this section, no rights under any
options may be exercised after the expiration of ten years from their Date of
Grant.

           (g) METHOD OF EXERCISE AND PAYMENT. Options may be exercised only by
written notice to the Company at its head office accompanied by payment of the
full option price for the shares of Common Stock as to which they are exercised.
The option price shall be paid in cash or by check or in shares of Common Stock
of the Company, or in any combination thereof. Shares of Common Stock
surrendered in payment of the option price shall have been held by the person
exercising the option for at least six months, unless otherwise permitted by the
Board. The value of shares delivered in payment of the option price shall be
their fair market value, as determined in accordance with Section 6(c) above, as
of the date of exercise. Upon receipt of such notice and payment, the Company
shall promptly issue and deliver to the optionee (or other person entitled to
exercise the option) a certificate or certificates for the number of shares as
to which the

                                       3

<PAGE>   4

exercise is made.

           (h) NON-TRANSFERABILITY. Options granted under this Plan shall not be
transferable by the holder thereof otherwise than by will or the laws of descent
and distribution or as permitted by Rule 16b-3 (or any successor provision)
under the Securities Exchange Act of 1934, as amended ("Rule 16b-3").

7.  LIMITATION OF RIGHTS.

           (a) NO RIGHT TO CONTINUE AS A DIRECTOR. Neither the Plan, nor the
granting of an option or any other action taken pursuant to the Plan, shall
constitute an agreement or understanding, express or implied, that the Company
will retain an option holder as a director for any period of time or at any
particular rate of compensation.

           (b) NO STOCKHOLDERS' RIGHTS FOR OPTIONS. A director shall have no
rights as a stockholder with respect to the shares covered by options until the
date the director exercises such options and pays the option price to the
Company, and no adjustment will be made for dividends or other rights for which
the record date is prior to the date such option is exercised and paid for.

8.  AMENDMENT OR TERMINATION.

           The Board may amend or terminate this Plan at any time, provided
that, to the extent necessary to comply with Rule 16b-3, this Plan shall not be
amended more than once every six months, other than to comport with changes in
the Code, ERISA or the rules thereunder.

9.  STOCKHOLDER APPROVAL.

           This Plan and the automatic grants made upon adoption thereof by the
Board of Directors are subject to approval by the stockholders of the Company by
the affirmative vote of the holders of a majority of the shares of Common Stock
of the Company present, or represented and entitled to vote, at a meeting duly
held in accordance with the laws of the State of Delaware. In the event such
approval is not obtained, all options granted under this Plan shall be void and
without effect.

10.  GOVERNING LAW.

           This Plan shall be governed by and interpreted in accordance with the
laws of the State of Delaware.


                                       4





<PAGE>   1
                                                        EXHIBIT 10.3



                          AGREEMENT AND PLAN OF MERGER

                                      AMONG

                          GELTEX PHARMACEUTICALS, INC.

                           SHINE ACQUISITION SUB, INC.

                                       AND

                              SUNPHARM CORPORATION


                           DATED AS OF AUGUST 13, 1999
<PAGE>   2


<TABLE>
                                                 TABLE OF CONTENTS

<S>                                                                                                              <C>
ARTICLE I THE MERGER..............................................................................................1

   1.1 THE MERGER.................................................................................................1
   1.2 EFFECTIVE TIME.............................................................................................2
   1.3 EFFECT OF THE MERGER.......................................................................................2
   1.4 CERTIFICATE OF INCORPORATION AND BY-LAWS OF SURVIVING CORPORATION..........................................2
   1.5 DIRECTORS AND OFFICERS.....................................................................................2
   1.6 MAXIMUM CONSIDERATION; CONVERSION OF COMPANY COMMON SHARES AND COMPANY PREFERRED SHARES....................2
   1.7 CANCELLATION OF TREASURY SHARES............................................................................4
   1.8 STOCK OPTIONS AND WARRANTS.................................................................................4
   1.9 CAPITAL STOCK OF MERGER SUB................................................................................6
   1.10 ADJUSTMENTS TO EXCHANGE RATIO.............................................................................6
   1.11 FRACTIONAL SHARES.........................................................................................6
   1.12 SURRENDER OF CERTIFICATES.................................................................................7
   1.13 FURTHER OWNERSHIP RIGHTS IN COMPANY COMMON SHARES AND COMPANY PREFERRED SHARES............................8
   1.14 CLOSING...................................................................................................9
   1.15 LOST, STOLEN OR DESTROYED CERTIFICATES....................................................................9
   1.16 TAX CONSEQUENCES..........................................................................................9
   1.17 DISSENTERS' RIGHTS........................................................................................9
   1.18  FURTHER ASSURANCES......................................................................................10
   1.19  CLOSING OF COMPANY TRANSFER BOOKS.......................................................................10

ARTICLE II REPRESENTATIONS AND WARRANTIES OF THE COMPANY.........................................................10

   2.1 ORGANIZATION AND QUALIFICATION; SUBSIDIARIES..............................................................11
   2.2 CERTIFICIATE OF INCORPORATION AND BY-LAWS.................................................................11
   2.3 CAPITALIZATION............................................................................................12
   2.4 AUTHORITY RELATIVE TO THIS AGREEMENT; REQUIRED VOTE.......................................................13
   2.5 NO CONFLICT; REQUIRED FILINGS AND CONSENTS................................................................14
   2.6 MATERIAL AGREEMENTS.......................................................................................15
   2.7 COMPLIANCE WITH AGREEMENTS AND LAW........................................................................15
   2.8 SEC FILINGS; FINANCIAL STATEMENTS.........................................................................16
   2.9 ABSENCE OF CERTAIN CHANGES OR EVENTS......................................................................17
   2.10 NO UNDISCLOSED LIABILITIES...............................................................................17
   2.11 ABSENCE OF LITIGATION....................................................................................17
   2.12 EMPLOYEE BENEFIT PLANS...................................................................................17
   2.13 EMPLOYMENT AND LABOR MATTERS.............................................................................20
   2.14 REGISTRATION STATEMENT; PROXY STATEMENT/PROSPECTUS.......................................................21
   2.15 ABSENCE OF RESTRICTIONS ON BUSINESS ACTIVITIES...........................................................21
   2.16 TITLE TO ASSETS; LEASES..................................................................................22
   2.17 TAXES....................................................................................................22
   2.18 ENVIRONMENTAL MATTERS....................................................................................25
   2.19 INTELLECTUAL PROPERTY....................................................................................26
   2.20 INSURANCE................................................................................................28
   2.21 BROKERS..................................................................................................28
   2.22 CERTAIN BUSINESS PRACTICES...............................................................................29
   2.23 INTERESTED PARTY TRANSACTIONS............................................................................29
   2.24 OPINION OF FINANCIAL ADVISOR.............................................................................29
   2.25 NO SUBSIDIARIES..........................................................................................29
   2.26 DISCLOSURE...............................................................................................29
   2.27 HSR FILING...............................................................................................29

                                                         i
</TABLE>
<PAGE>   3


<TABLE>
<S>                                                                                                              <C>
ARTICLE III REPRESENTATIONS AND WARRANTIES OF PARENT AND MERGER SUB..............................................30

   3.1 ORGANIZATION AND QUALIFICATION............................................................................30
   3.2 CAPITALIZATION............................................................................................30
   3.3 AUTHORIZATION OF AGREEMENT................................................................................31
   3.4 APPROVALS.................................................................................................31
   3.5 NO VIOLATION..............................................................................................31
   3.6 REPORTS...................................................................................................32
   3.7 ABSENCE OF CERTAIN CHANGES OR EVENTS......................................................................32
   3.8 REGISTRATION STATEMENT; PROXY STATEMENT/PROSPECTUS........................................................32
   3.9 ABSENCE OF LITIGATION.....................................................................................33
   3.10 COMPLIANCE WITH LAWS.....................................................................................33
   3.11 TAXES....................................................................................................33
   3.12 YEAR 2000 COMPLIANCE.....................................................................................34
   3.13 PARENT INTELLECTUAL PROPERTY RIGHTS......................................................................34

ARTICLE IV CONDUCT OF BUSINESS PENDING THE MERGER................................................................34

   4.1 CONDUCT OF BUSINESS BY THE COMPANY PENDING THE MERGER.....................................................34
   4.2 SOLICITATION OF OTHER PROPOSALS...........................................................................37

ARTICLE V ADDITIONAL AGREEMENTS..................................................................................39

   5.1 PROXY STATEMENT/PROSPECTUS; REGISTRATION STATEMENT........................................................39
   5.2 MEETING OF COMPANY STOCKHOLDERS...........................................................................40
   5.3 ACCESS TO INFORMATION; CONFIDENTIALITY....................................................................41
   5.4 ALL REASONABLE EFFORTS; FURTHER ASSURANCES................................................................41
   5.5 STOCK OPTIONS AND WARRANTS................................................................................42
   5.6 REGISTRATION RIGHTS.......................................................................................44
   5.7 NOTIFICATION OF CERTAIN MATTERS...........................................................................44
   5.8 LISTING ON THE NASDAQ.....................................................................................45
   5.9 PUBLIC ANNOUNCEMENTS......................................................................................45
   5.10 TAKEOVER LAWS............................................................................................45
   5.11 ACCOUNTANT'S LETTERS.....................................................................................46
   5.12 INDEMNIFICATION OF DIRECTORS AND OFFICERS................................................................46
   5.13 COVENANTS FOR TAX-FREE STATUS............................................................................46
   5.14 STOCKHOLDER AGREEMENT....................................................................................46
   5.15 RELEASE AGREEMENTS.......................................................................................47
   5.16 AFFILIATE AGREEMENTS.....................................................................................47
   5.17 SEC FILINGS..............................................................................................48
   5.18 MAINTENANCE, PROSECUTION AND FILING OBLIGATIONS..........................................................48

ARTICLE VI CONDITIONS OF MERGER..................................................................................48

   6.1 CONDITIONS TO OBLIGATION OF EACH PARTY TO EFFECT THE MERGER...............................................48
   6.2 ADDITIONAL CONDITIONS TO OBLIGATIONS OF PARENT AND MERGER SUB.............................................49
   6.3 ADDITIONAL CONDITIONS TO OBLIGATIONS OF THE COMPANY.......................................................51

ARTICLE VII TERMINATION, AMENDMENT AND WAIVER....................................................................52

   7.1 TERMINATION...............................................................................................52
   7.2 EFFECT OF TERMINATION.....................................................................................53
   7.3 FEES AND EXPENSES.........................................................................................53
   7.4 AMENDMENT.................................................................................................55
   7.5 WAIVER....................................................................................................55

ARTICLE VIII GENERAL PROVISIONS..................................................................................55

   8.1 SURVIVAL OF REPRESENTATIONS AND WARRANTIES................................................................55

                                                        ii
</TABLE>
<PAGE>   4


<TABLE>
<S>                                                                                                              <C>
   8.2 NOTICES...................................................................................................55
   8.3 DISCLOSURE SCHEDULES......................................................................................57
   8.4 CERTAIN DEFINITIONS.......................................................................................57
   8.5 INTERPRETATION............................................................................................61
   8.6 SEVERABILITY..............................................................................................61
   8.7 ENTIRE AGREEMENT..........................................................................................61
   8.8 ASSIGNMENT................................................................................................61
   8.9 PARTIES IN INTEREST.......................................................................................61
   8.10 FAILURE OR INDULGENCE NOT WAIVER; REMEDIES CUMULATIVE....................................................61
   8.11 GOVERNING LAW............................................................................................61
   8.12 COUNTERPARTS.............................................................................................62
</TABLE>

EXHIBIT A -           Form of Stockholder Agreement
EXHIBIT B -           Certificate of Merger
EXHIBIT C -           Form of Release Agreement
EXHIBIT D -           Form of Affiliate Agreement
EXHIBIT E -           Form of Opinion of Andrews & Kurth L.L.P.
EXHIBIT F -           Form of Opinion of Mintz, Levin, Cohn, Ferris, Glovsky and
                      Popeo, P.C.

                                       iii
<PAGE>   5


                                    SCHEDULES

<TABLE>
<CAPTION>
COMPANY AND COMPANY'S SUBSIDIARIES' SCHEDULES

<S>                        <C>
         2.1(c)            Subsidiaries
         2.3(a)            Stock Appreciation Rights; Other Rights
         2.3(b)            Capitalization:  Company and Subsidiaries, Capital Stock
         2.5(a)            Conflict; Required Filing
         2.5(b)            Company Approvals
         2.6               Material Agreements
         2.7               Permits
         2.8               SEC Filings and Financial Statements
         2.11              Litigation
         2.12(a)           Employee Benefit Plans
         2.12(e)           Benefits; Acceleration
         2.12(g)           Medical Benefits
         2.12(i)           Severance Payments
         2.12(k)           Holders of Option, Warrant or Other Right to Purchase Capital Stock
         2.13(a)           Employment and Consultant Agreements
         2.13(b)           Employee Controversies
         2.15              Restrictions of Business Activity
         2.16              Real Property
         2.17              Taxes
         2.17(m)           Net Operating Loss; Capital Loss Carry Forwards
         2.17(n)           Limitations of Net Operating Loss
         2.18              Environmental Matters
         2.19(a)           Intellectual Property:  Patents, Trademarks, Copyrights
         2.19(b)           Intellectual Property:  Non-Exclusive Intellectual Property Rights
         2.19(c)           Maintenance Fees
         2.20              Insurance
         2.21              Broker Agreements
         2.23              Interested Parties

     OTHER SCHEDULES

         4.1(l)            Related Party Agreements, Arrangements, Understandings
         5.15              Release Agreements
         5.16              Affiliates
         8.4               Events, Changes, and Circumstances
</TABLE>

                                       iv
<PAGE>   6


                  AGREEMENT AND PLAN OF MERGER, dated as of August 13, 1999 (the
"Agreement") among GELTEX PHARMACEUTICALS, INC., a Delaware corporation
("Parent"), SHINE ACQUISITION SUB, INC., a Delaware corporation and a wholly
owned subsidiary of Parent ("Merger Sub"), and SUNPHARM CORPORATION, a Delaware
corporation (the "Company").

                  WHEREAS, the Boards of Directors of Parent, Merger Sub and the
Company have each determined that it is in the best interests of their
respective stockholders for Parent to acquire the Company upon the terms and
subject to the conditions set forth herein;

                  WHEREAS, in furtherance of such acquisition, the Boards of
Directors of Parent, Merger Sub and the Company have each approved the merger
(the "Merger") of Merger Sub with and into the Company, in accordance with the
General Corporation Law of the State of Delaware (the "DGCL") and subject to the
conditions set forth herein, which Merger will result in, among other things,
the Company becoming a wholly owned subsidiary of Parent, and all of the issued
and outstanding shares of the common stock of the Company, $.0001 par value per
share (the "Company Common Shares") and all of the issued and outstanding Series
A Redeemable Convertible Preferred Stock and Series B Redeemable Convertible
Preferred Stock of the Company, $.001 par value per share (collectively, the
"Company Preferred Shares") will be exchanged and converted into shares of
common stock, par value $0.01 per share, of Parent (the "Parent Common Stock")
with certain Parent Rights as described herein;

                  WHEREAS, as a condition to the willingness of, and as an
inducement to, Parent and Merger Sub to enter into this Agreement,
contemporaneously with the execution and delivery of this Agreement, certain
holders of Company Common Shares and Company Preferred Shares are entering into
agreements (the "Stockholder Agreements") in the form of Exhibit A attached
hereto, providing for certain actions relating to the transactions contemplated
by this Agreement, including their agreement to vote Company Common Shares and
Company Preferred Shares in favor of the Merger;

                  WHEREAS, for federal income tax purposes, it is intended that
the Merger shall qualify as a tax-free reorganization within the meaning of
Section 368(a) of the Code and the United States Treasury Regulations
promulgated thereunder; and

                  NOW, THEREFORE, in consideration of the foregoing and the
mutual representations, warranties, covenants and agreements herein contained,
and intending to be legally bound hereby, Parent, Merger Sub and the Company
hereby agree as follows:

                                    ARTICLE I

                                   THE MERGER

         1.1 THE MERGER. At the Effective Time (as defined in Section 1.2) and
subject to and upon the terms and conditions of this Agreement and the
provisions of the DGCL, Merger Sub shall be merged with and into the Company,
the separate corporate existence of Merger Sub shall
<PAGE>   7


cease and the Company shall, as the surviving corporation in the Merger,
continue its existence under the provisions of the DGCL as a wholly owned
subsidiary of Parent. The Company as the surviving corporation after the Merger
is hereinafter sometimes referred to as the "Surviving Corporation."

         1.2 EFFECTIVE TIME. As promptly as practicable after the satisfaction
or, to the extent permitted hereunder, waiver of the conditions set forth in
Article VI of this Agreement, the parties hereto shall cause the Merger to be
consummated by filing the Certificate of Merger substantially in the form of
Exhibit B (the "Certificate of Merger"), along with a certified copy of this
Agreement, if required, with the Secretary of State of the State of Delaware,
executed in accordance with the relevant provisions of the DGCL (the date and
time of such filing, or such later date and time as may be specified in the
Certificate of Merger by mutual agreement of Parent, Merger Sub and the Company,
being the "Effective Time").

         1.3 EFFECT OF THE MERGER. At the Effective Time, the effect of the
Merger shall be as provided in the applicable provisions of the DGCL. Without
limiting the generality of the foregoing, and subject thereto, at the Effective
Time all the property, rights, privileges, powers and franchises of the Company
and Merger Sub shall vest in the Surviving Corporation, and all debts,
liabilities and duties of the Company and Merger Sub shall become the debts,
liabilities and duties of the Surviving Corporation.

         1.4 CERTIFICATE OF INCORPORATION AND BY-LAWS OF SURVIVING CORPORATION.
Unless otherwise determined by Parent prior to the Effective Time, at the
Effective Time the Certificate of Incorporation of the Company, as amended by
the Certificate of Merger, shall be the Certificate of Incorporation of the
Surviving Corporation until thereafter amended as provided by the DGCL. The
by-laws of the Merger Sub shall be the by-laws of the Surviving Corporation
until thereafter amended as provided by the DGCL.

         1.5 DIRECTORS AND OFFICERS. The directors of Merger Sub immediately
prior to the Effective Time shall be the initial directors of the Surviving
Corporation, each to hold office in accordance with the Certificate of
Incorporation of the Surviving Corporation. The officers of the Merger Sub
immediately prior to the Effective Time shall be the initial officers of the
Surviving Corporation, in each case until their respective successors are duly
elected or appointed and qualified or until their earlier death, resignation or
removal in accordance with the Surviving Corporation's Certificate of
Incorporation and by-laws. Prior to the Effective Time, the Company shall
deliver to Parent resignation letters of each of the directors of the Company to
be effective as of such Effective Time.

         1.6 MAXIMUM CONSIDERATION; CONVERSION OF COMPANY COMMON SHARES AND
COMPANY PREFERRED SHARES. Notwithstanding anything in this Agreement to the
contrary, the maximum consideration payable by Parent with respect to the
Company Common Shares and Company Preferred Shares issued and outstanding
immediately prior to the Effective Time shall be an aggregate of the number of
shares of Parent Common Stock, subject to adjustment as hereinafter provided in
this Section 1.6, as is obtained by dividing (A) the Acquisition Amount by (B)
the Closing Average, as adjusted pursuant to Section 1.6(c) hereof, rounded to
the nearest

                                       2
<PAGE>   8


whole share. For purposes of this Agreement, "Acquisition Amount" shall mean the
result of (x) $16,540,462, minus (y) the product of (1) $2.00 times (2) the
number of shares covered by options or warrants (other than those warrants
issued or to be issued to Petkevich & Partners, L.L.C. for the purchase of
200,000 Company Common Shares), which options or warrants are vested and
exercisable at an exercise price or strike price of $2.00 or less per share and
are not exercised immediately prior to the Effective Time.

         At the Effective Time, by virtue of the Merger and without any action
on the part of the parties hereto or the holders of the following securities:

                  (a) Subject to the other provisions of this Article I, each
share of Series A Redeemable Convertible Preferred Stock, par value $.001 per
share (the "Series A Preferred Stock") and each share of Series B Redeemable
Convertible Preferred Stock, par value $.001 per share (the "Series B Preferred
Stock") issued and outstanding immediately prior to the Effective Time (other
than any Company Preferred Shares to be canceled pursuant to Section 1.7 and any
Dissenting Shares (as defined in Section 1.17)) shall be converted automatically
into the right to receive one hundred fifty percent (150%) of the Exchange Ratio
Fraction of a fully paid and nonassessable share of Parent Common Stock,
together with cash, if any, in lieu of any fraction of a share of Parent Common
Stock, pursuant to Section 1.11 (collectively, the "Preferred Merger
Consideration").

                  (b) Subject to the other provisions of this Article I, each
Company Common Share issued and outstanding immediately prior to the Effective
Time (other than any Company Common Shares to be canceled pursuant to Section
1.7 and any Dissenting Shares (as defined in Section 1.17)) shall be converted
automatically into the right to receive the Exchange Ratio Fraction of a fully
paid and nonassessable share of Parent Common Stock, together with cash, if any,
in lieu of any fraction of a share of Parent Common Stock, pursuant to Section
1.11 the ("Common Merger Consideration" and, together with the Preferred Merger
Consideration, the "Merger Consideration").

                  (c) For purposes of this Agreement, the "Exchange Ratio
Fraction" shall mean the quotient (calculated to the nearest five (5) decimal
places) obtained by dividing (x) the Acquisition Amount by (y) the Closing
Average, and by dividing the quotient computed thereby by the Company Shares
Number (as defined below). As used herein, the "Closing Average" shall be the
average closing price per share of Parent Common Stock (rounded to the nearest
cent) on the NASDAQ National Market ("NASDAQ") (as reported in the Wall Street
Journal, or, if not reported therein, any other authoritative source selected by
Parent) for the twenty (20) consecutive trading days ending on the second
trading day immediately prior to the Effective Time; provided, however, that if
(A) such average is $13.80 or less, then the Closing Average shall be $13.80 and
(B) such average is $16.36 or more, then the Closing Average shall be $16.36. As
used herein, "Company Shares Number" means the sum of (A) (i) all Company Common
Shares outstanding immediately prior to the Effective Time (including all
Company Common Shares issued upon the exercise or cancellation of any options to
purchase Company Common Shares or any warrants to purchase Company Common Shares
or upon the conversion or exchange of any Company Preferred Shares), minus (ii)
Company Common Shares to be canceled pursuant to Section 1.7 and any Dissenting
Shares (as defined in Section 1.17), plus (B) an amount equal to the product
obtained by multiplying (i) one hundred fifty percent (150%), by

                                       3
<PAGE>   9


(ii) the number of Company Preferred Shares outstanding immediately prior to the
Effective Time (other than the Company Preferred Shares to be canceled pursuant
to Section 1.7). As used herein, the "Measurement Date Average" shall be the
average closing price per share of Parent Common Stock on NASDAQ for the twenty
(20) consecutive trading days ending on August 11, 1999.

                  (d) Each share of Parent Common Stock to be issued upon
conversion of Company Common Shares and Company Preferred Shares in accordance
with this Section 1.6 shall include the corresponding percentage of a Series A-1
Junior Participating Preferred Stock Purchase Right of Parent (a "Parent Right")
issued pursuant to the Rights Agreement dated as of March 1, 1996 between the
Company and American Stock Transfer & Trust Company, as amended (as so amended,
the "Parent Rights Agreement"). Prior to the Distribution Date (as defined in
the Parent Rights Agreement), all references in this Agreement to the Parent
Common Stock issued in connection with the Merger shall be deemed to include
Parent Rights.

                  (e) As of the Effective Time, all Company Common Shares and
all Company Preferred Shares issued and outstanding immediately prior to the
Effective Time shall no longer be outstanding and all Company Common Shares and
all Company Preferred Shares shall automatically be canceled and retired and
shall cease to exist, and each holder of a certificate representing any such
Company Common Shares and all Company Preferred Shares shall cease to have any
rights with respect thereto, except the right to receive the Merger
Consideration and any cash in lieu of fractional shares of Parent Common Stock
to be issued or paid in consideration therefor upon surrender of such
certificate in accordance with Section 1.12 hereof, without interest.

         1.7 CANCELLATION OF TREASURY SHARES. Each share of Company Common
Shares or Company Preferred Shares held in the treasury of the Company and each
share of Company Common Shares or Company Preferred Shares, if any, owned by
Merger Sub or Parent, immediately prior to the Effective Time shall be canceled
and extinguished without any conversion thereof.

         1.8      STOCK OPTIONS AND WARRANTS.

                  (a) As soon as practicable after the execution of this
Agreement, the Company shall, pursuant to the Company's Amended and Restated
1994 Stock Option Plan (the "1994 Plan"), (i) notify each holder of an
outstanding option issued pursuant to the 1994 Plan of the proposed Merger, (ii)
provide for the accelerated vesting of each outstanding option so that each such
option shall become fully exercisable, (iii) notify each such holder that each
option shall, unless exercised by the holder in accordance with its terms, be
canceled and terminate on the date which is fifteen (15) days from the date of
such notice, and (iv) cause the 1994 Plan to be terminated. As soon as
practicable after the execution of this Agreement, the Company shall use
commercially reasonable best efforts to cause the exercise or termination of all
other then outstanding employee and consultant stock options and all
non-employee director stock options, including without limitation, the incentive
stock options and non-qualified stock options issued pursuant to the Company's
1995 Non-employee Director's Stock Option Plan (the "1995 Plan")

                                       4
<PAGE>   10


and all stock options granted pursuant to resolutions of the Company's Board of
Directors outside of any option plan. Notwithstanding the foregoing, under no
circumstances shall the Company be required to offer any incentives or other
consideration for the termination of such options.

                  (b) Subject to Section 1.8(a) of this Agreement, at the
Effective Time, each of the Company's then outstanding employee and consultant
stock options and non-employee director stock options (collectively the "Company
Options") which are outstanding and have not been terminated, exercised or
otherwise converted as of the Effective Time shall cease to represent the right
to acquire Company Common Shares, and shall, by virtue of the Merger and without
any further action on the part of any holder thereof, be converted into and
become the right to acquire a number of shares of Parent Common Stock determined
by multiplying the number of shares of Company Common Stock covered by such
Company Option immediately prior to the Effective Time by the Exchange Ratio
Fraction (rounded down to the nearest whole number of shares), at an exercise
price per share of Parent Common Stock equal to the exercise price in effect
under such Company Option immediately prior to the Effective Time divided by the
Exchange Ratio Fraction (rounded up to the nearest cent), which option to
purchase Parent Common Stock shall contain the same term, vesting schedule and
otherwise be on substantially the same terms and conditions as set forth in the
assumed Company Option, except that any Company Option qualifying or intended to
qualify as an "incentive stock option" under Section 422 of the Internal Revenue
Code of 1986, as amended (the "Code") shall not qualify as an "incentive stock
option" under Section 422 of the Code (any such assumed Company Option being
herein referred to as an "Assumed Option").

                  (c) The Company shall take all actions necessary or reasonably
requested by Parent to ensure that following the Effective Time no holder of any
Company Options or rights pursuant to, nor any participant in, the 1994 Plan,
the 1995 Plan or any other plan, program or arrangement providing for the
issuance or grant of any interest in respect of the capital stock of the Company
and any of its Subsidiaries will have any right thereunder to acquire equity
securities, or any right to payment in respect of the equity securities, of the
Company, any of its Subsidiaries or the Surviving Corporation, except as
provided in subsection (b) above.

                  (d) Parent shall take all corporate action necessary (i) to
reserve for issuance, and (ii) to register under the Securities Act of 1933 (the
"Securities Act") the issuance of, a sufficient number of shares of Parent
Common Stock for delivery upon exercise of the Assumed Options in accordance
with this Section 1.8.

                  (e) As soon as practicable after the execution of this
Agreement, the Company shall use commercially reasonable best efforts to cause
the exercise or termination of all then issued and outstanding warrants to
acquire shares of Company Common Stock or securities convertible into Common
Stock (collectively, the "Company Warrants"). At the Effective Time, each
Company Warrant that is outstanding and has not been terminated, exercised or
otherwise converted as of the Effective Time shall be assumed by Parent;
provided that such Company Warrants shall by their express terms reflect, or
shall be amended by the Company and the holder thereof to reflect, the different
security and the number of shares of such

                                       5
<PAGE>   11


security covered by such agreement based on the conversion of Company Common
Shares into Parent Common Stock. All of the holders of such Company Warrants
issued and outstanding as of the date of this Agreement are listed on Section
2.3(b) of the Company Disclosure Schedule attached hereto. The Company shall
take all actions necessary or reasonably requested by Parent to ensure that
following the Effective Time no holder of any Company Warrant will have any
right thereunder to acquire equity securities of the Company or any of its
Subsidiaries, or any right to payment in respect of the equity securities of the
Company, any of its Subsidiaries or the Surviving Corporation, except as
provided in this subsection (e).

                  (f) As soon as practicable after the execution of this
Agreement, the Company shall use its commercially reasonable best efforts to
cause the holders of warrants or warrant certificates issued pursuant to that
Unit Purchase Agreement dated March 28, 1997 (the "1997 Unit Purchase
Agreement") to (i) surrender such warrants or warrant certificates (the "1997
Warrants") in exchange for an aggregate of 158,512 Company Common Shares and
(ii) agree to terminate the 1997 Unit Purchase Agreement.

                  (g) Parent shall take all corporate action necessary (i) to
reserve for issuance, and (ii) to register under the Securities Act, a
sufficient number of shares of Parent Common Stock for delivery upon exercise of
the Company Warrants in accordance with this Section 1.8.

         1.9 CAPITAL STOCK OF MERGER SUB. Each share of common stock, par value
$.01 per share, of Merger Sub (the "Merger Sub Common Stock") issued and
outstanding immediately prior to the Effective Time shall be converted into and
exchanged for one validly issued, fully paid and nonassessable share of Common
Stock, par value $.01 per share, of the Surviving Corporation. Each stock
certificate of Merger Sub evidencing ownership of any Merger Sub Common Stock
shall continue to evidence ownership of such shares of capital stock of the
Surviving Corporation.

         1.10 ADJUSTMENTS TO EXCHANGE RATIO FRACTION. Without limiting any other
provision of this Agreement, the Exchange Ratio Fraction shall be
correspondingly adjusted to reflect fully the effect of any stock split, reverse
split, stock dividend (including any dividend or distribution of securities
convertible into Parent Common Stock or Company Common Shares), reorganization,
recapitalization, reclassification, conversion, consolidation, contribution or
exchange of shares or other like change with respect to Parent Common Stock or
Company Common Shares occurring after the date hereof and prior to the Effective
Time.

         1.11 FRACTIONAL SHARES. No fraction of a share of Parent Common Stock
will be issued hereunder, but in lieu thereof each holder of Company Common
Shares who would otherwise be entitled to a fraction of a share of Parent Common
Stock (after aggregating all fractional shares of Parent Common Stock to be
received by such holder) shall receive from Parent an amount of cash (rounded
down to the nearest whole cent) equal to the product of such fraction multiplied
by the Closing Average.

                                       6
<PAGE>   12


         1.12     SURRENDER OF CERTIFICATES.

                  (a) EXCHANGE AGENT. Prior to the Effective Time, Parent shall
designate one or more Persons, to act as Exchange Agent hereunder.

                  (b) PARENT TO PROVIDE COMMON STOCK. Promptly after the
Effective Time, Parent shall make available to the Exchange Agent for exchange
in accordance with this Article I, through such reasonable procedures as Parent
may adopt, the shares of Parent Common Stock issuable pursuant to Section 1.6 in
exchange for outstanding Company Common Shares and outstanding Company Preferred
Shares, together with an estimated amount of cash to be paid pursuant to Section
1.11 in lieu of fractional shares.

                  (c) EXCHANGE PROCEDURES. Promptly after the Effective Time,
the Surviving Corporation shall cause the Exchange Agent to mail to each holder
of record of a certificate or certificates (the "Certificates") which
immediately prior to the Effective Time represented outstanding Company Common
Shares and Company Preferred Shares whose shares were converted into the right
to receive shares of Parent Common Stock pursuant to Section 1.6, a letter of
transmittal (which shall specify that delivery shall be effected, and risk of
loss and title to the Certificates shall pass, only upon delivery of the
Certificates to the Exchange Agent and shall be in such form and have such other
provisions as Parent may reasonably specify) and instructions for use in
effecting the surrender of the Certificates in exchange for certificates
representing shares of Parent Common Stock and cash in lieu of the fraction of a
share of Parent Common Stock, if any, pursuant to Section 1.11 hereof. Upon
surrender of a Certificate for cancellation to the Exchange Agent, together with
such letter of transmittal, duly completed and validly executed in accordance
with the instructions thereto, the holder of such Certificate shall be entitled
to receive in exchange therefor, a certificate representing the number of whole
shares of Parent Common Stock and payment in lieu of fractional shares which
such holder has the right to receive pursuant to Section 1.11, and the
Certificate so surrendered shall forthwith be canceled. Until so surrendered,
each outstanding Certificate that, prior to the Effective Time, represented
Company Common Shares or Company Preferred Shares will be deemed from and after
the Effective Time, for all corporate purposes, other than the payment of
dividends, to evidence the ownership of the number of full shares of Parent
Common Stock into which such Company Common Shares and Company Preferred Shares
shall have been so converted and the right to receive an amount in cash in lieu
of the issuance of any fractional shares in accordance with Section 1.11. Any
portion of the shares of Parent Common Stock deposited with the Exchange Agent
pursuant to this Section 1.12(c) which remains undistributed to the holders of
the Certificates representing Company Common Shares or Company Preferred Shares
for twelve (12) months after the Effective Time shall be delivered to Parent,
upon demand, and any holders of Company Common Shares or Company Preferred
Shares who have not theretofore complied with this Article I shall thereafter
look only to Parent for Parent Common Stock, any cash in lieu of fractional
shares of Parent Common Stock and any dividends or distributions with respect to
Parent Common Stock to which such holders may be entitled.

                  (d) DISTRIBUTIONS WITH RESPECT TO UNEXCHANGED SHARES. No
dividends or other distributions declared or made after the Effective Time with
respect to Parent Common

                                       7
<PAGE>   13


Stock with a record date after the Effective Time will be paid to the holder of
any unsurrendered Certificate with respect to the shares of Parent Common Stock
represented thereby until the holder of record of such Certificate shall
surrender such Certificate. Subject to applicable escheat Law, following
surrender of any such Certificate, there shall be paid to the record holder of
the certificates representing whole shares of Parent Common Stock issued in
exchange therefor, without interest, at the time of such surrender, the amount
of dividends or other distributions with a record date after the Effective Time
theretofore paid with respect to such whole shares of Parent Common Stock.

                  (e) TRANSFERS OF OWNERSHIP. If any certificate for shares of
Parent Common Stock is to be issued in a name other than that in which the
Certificate surrendered in exchange therefor is registered, it will be a
condition of the issuance thereof that the Certificate so surrendered will be
properly endorsed and otherwise in proper form for transfer and that the Person
requesting such exchange will have paid to Parent, or any agent designated by
it, any transfer or other taxes required by reason of the issuance of a
certificate for shares of Parent Common Stock in any name other than that of the
registered holder of the certificate surrendered, or established to the
satisfaction of Parent or any agent designated by it that such tax has been paid
or is not payable.

                  (f) NO LIABILITY. Notwithstanding anything to the contrary in
this Agreement, none of the Exchange Agent, Parent, Merger Sub or the Surviving
Corporation shall be liable to a holder of Company Common Shares or Company
Preferred Shares for any Parent Common Stock or any amount properly paid to a
public official pursuant to any applicable abandoned property, escheat or
similar Law.

                  (g) WITHHOLDING OF TAX. Parent or the Exchange Agent will be
entitled to deduct and withhold from the consideration otherwise payable
pursuant to this Agreement to any holder of Company Common Shares or any holder
of Company Preferred Shares, as the case may be, such amounts as Parent (or any
Affiliate thereof) or the Exchange Agent are required to deduct and withhold
with respect to the making of such payment under the Code, or any provision of
federal, state, local or foreign tax law. To the extent that amounts are so
withheld by Parent or the Exchange Agent, such withheld amounts will be treated
for all purposes of this Agreement as having been paid to the holder of the
Company Common Shares or Company Preferred Shares, as the case may be, in
respect of whom such deduction and withholding were made by Parent.

         1.13 FURTHER OWNERSHIP RIGHTS IN COMPANY COMMON SHARES AND COMPANY
PREFERRED SHARES. All shares of Parent Common Stock issued upon the surrender
for exchange of Company Common Shares and Company Preferred Shares in accordance
with the terms of this Article I (including any cash paid in respect thereof)
shall be deemed to have been issued in full satisfaction of all rights
pertaining to such Company Common Shares and Company Preferred Shares under this
Article I, and there shall be no further registration of transfers on the
records of the Surviving Corporation of Company Common Shares and Company
Preferred Shares which were outstanding immediately prior to the Effective Time.
If, after the Effective

                                        8
<PAGE>   14
Time, Certificates are presented to the Surviving Corporation for any reason,
they shall be canceled and exchanged as provided in this Article I.

         1.14 CLOSING. Unless this Agreement shall have been terminated and the
transactions contemplated by this Agreement abandoned pursuant to the provisions
of Article VII, and subject to the provisions of Article VI, the closing of the
Merger (the "Closing") will take place at 10:00 a.m. (Eastern time) on a date
(the "Closing Date") to be mutually agreed upon by the parties, which date shall
be not later than the third Business Day after all the conditions set forth in
Article VI shall have been satisfied (or waived in accordance with Section 7.5,
to the extent the same may be waived), unless another time and/or date is agreed
to in writing by the parties. The Closing shall take place at the offices of
Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., One Financial Center,
Boston, Massachusetts, unless another place is agreed to in writing by the
parties.

         1.15 LOST, STOLEN OR DESTROYED CERTIFICATES. In the event any
Certificates shall have been lost, stolen or destroyed, the Exchange Agent shall
issue in exchange for such lost, stolen or destroyed certificates, upon the
making of an affidavit of that fact by the holder thereof, such shares of Parent
Common Stock and cash for fractional shares, if any, as may be required pursuant
to Section 1.11; provided, however, that Parent may, as a condition precedent to
the issuance thereof, require the owner of such lost, stolen or destroyed
certificates to deliver a bond in such sum as it may reasonably direct as
indemnity against any claim that may be made against Parent or the Exchange
Agent with respect to the Certificates alleged to have been lost, stolen or
destroyed.

         1.16 TAX CONSEQUENCES. For federal income tax purposes, the parties
intend that the Merger be treated as a reorganization within the meaning of
Section 368(a)(1)(A) and 368(a)(2)(E) of the Code, and that this Agreement shall
be, and is hereby, adopted as a plan of reorganization for purposes of Section
368 of the Code. The parties shall not take a position on any Tax Return
inconsistent with this Section 1.16.

         1.17 DISSENTERS' RIGHTS. All of the Persons who have executed and
delivered a Stockholder Agreement shall have consented to the Merger and shall
have delivered their stock certificates in accordance with the terms hereof.
Holders of 100% of the Company Preferred Shares and holders of the requisite
number of the Company Common Shares shall have consented to the Merger and
delivered all of their capital stock to the Parent or the Exchange Agent in
accordance with the terms hereof, and the holders of not more than 2% of the
issued and outstanding Company Common Shares shall have exercised, or shall have
any continued right to exercise, appraisal or dissenter's rights.
Notwithstanding anything in this Agreement to the contrary, any Company Common
Shares or Company Preferred Shares outstanding immediately prior to the
Effective Time and held by a holder who has not voted in favor of the Merger or
delivered a valid, unrevoked proxy in favor of the Merger, or consented thereto
in writing and who has delivered written notice to the Company objecting to the
Merger and demanding payment for his shares as required in accordance, and has
otherwise complied, with the applicable provisions of the DGCL ("Dissenting
Shares"), shall not be converted into the right to receive the Parent Common
Stock, unless and until such holder fails to elect to dissent from the

                                       9
<PAGE>   15


Merger or effectively withdraws or otherwise loses his right to payment of the
fair value of his shares under the provisions of the DGCL. If, after the
Effective Time, any such holder fails to perfect or effectively withdraws or
loses his right to such payment, such Dissenting Shares shall thereupon be
treated as if they had been converted as of the Effective Time into the right to
receive Parent Common Stock to which such holder is entitled, without interest
or dividends thereon. Any amounts paid to holders of Dissenting Shares in an
appraisal proceeding will be paid by the Surviving Corporation out of its own
funds and will not be paid by Parent or Merger Sub. The Company shall not,
except with the prior written consent of Parent, make any payment with respect
to any such demands or offer to settle or settle any such demands.

         1.18 FURTHER ASSURANCES. If at any time after the Effective Time the
Surviving Corporation shall consider or be advised that any deeds, bills of
sale, assignments or assurances or any other acts or things are necessary,
desirable or proper (a) to vest, perfect or confirm, of record or otherwise, in
the Surviving Corporation its right, title or interest in, to or under any of
the rights, privileges, immunities, powers, purposes, franchises, properties or
assets of the Company or Merger Sub, or (b) otherwise to carry out the purposes
of this Agreement, the Surviving Corporation and its proper officers and
directors or their designees shall be authorized to solicit in the name of the
Company or Merger Sub any third party consents or other documents required to be
delivered by any third party, to execute and deliver, in the name and on behalf
of the Company or Merger Sub, all such deeds, bills of sale, assignments and
assurances and do, in the name and on behalf of the Company or Merger Sub, all
such other acts and things necessary, desirable or proper to vest, perfect or
confirm its right, title or interest in, to or under any of the rights,
privileges, immunities, powers, purposes, franchises, properties or assets of
the Company or Merger Sub and otherwise to carry out the purposes of this
Agreement.

         1.19 CLOSING OF COMPANY TRANSFER BOOKS. At the Effective Time, the
stock transfer books of the Company shall be closed and no transfer of Company
Common Shares or Company Preferred Shares shall thereafter be made. If, after
the Effective Time, certificates representing shares of Company Common Shares or
Company Preferred Shares are presented to the Surviving Corporation, they shall
be canceled and presented to the Exchange Agent in accordance with Section 1.12.


                                   ARTICLE II

                  REPRESENTATIONS AND WARRANTIES OF THE COMPANY

         The Company hereby represents and warrants to Parent and Merger Sub
that the statements contained in this Article II are correct and complete as of
the date of this Agreement and will be correct and complete on the Closing Date,
except as disclosed in the disclosure schedule dated the date hereof, certified
by the President and Chief Executive Officer of the Company and delivered by the
Company to Parent and Merger Sub simultaneously herewith (which disclosure
schedule shall contain specific references to the representations and warranties
to which the disclosures contained therein relate and an item on such disclosure
schedule shall be

                                       10
<PAGE>   16


deemed to qualify only the particular subsection or subsections specified for
such item) (the "Company Disclosure Schedule") as follows:

         2.1      ORGANIZATION AND QUALIFICATION; SUBSIDIARIES.

                  (a) The Company is a corporation duly organized, validly
existing and in good standing under the laws of its jurisdiction of
incorporation. The Company has all the requisite corporate power and authority
and is in possession of all franchises, grants, authorizations, licenses,
permits, easements, consents, certificates, approvals and Orders ("Company
Approvals") necessary to own, lease and operate its properties and to carry on
its business as it is now being conducted, except where the failure to have such
power, authority and Company Approvals would not, individually or in the
aggregate, have a Material Adverse Effect. The Company is duly qualified or
licensed as a foreign corporation to do business, and is in good standing, in
each jurisdiction where the character of the properties owned, leased or
operated by it or the nature of its activities makes such qualification or
licensing necessary, except in such instances where the failure to be so duly
qualified, or licensed and in good standing or to have such power, authority and
Company Approvals would not, individually or in the aggregate, have a Material
Adverse Effect.

                  (b) Each Subsidiary of the Company is a legal entity, duly
organized, validly existing and in good standing under the laws of its
respective jurisdiction of incorporation or organization and has all the
requisite power and authority, and is in possession of all franchises, grants,
authorizations, licenses, permits, easements, consents, certificates, approvals
and Orders (with respect to each such Subsidiary, "Subsidiary Approvals")
necessary to own, lease and operate its properties and to carry on its business
as it is now being conducted. Each Subsidiary is duly qualified or licensed as a
foreign corporation to do business, and is in good standing, in each
jurisdiction where the character of the properties owned, leased or operated by
it or the nature of its activities makes such qualification or licensing
necessary.

                  (c) Section 2.1(c) of the Company Disclosure Schedule sets
forth, as of the date hereof, a true and complete list of all of the Company's
directly and indirectly owned Subsidiaries, together with the jurisdiction of
incorporation or organization of each Subsidiary and the percentage of each
Subsidiary's outstanding capital stock or other equity or other interest owned
by the Company or another direct or indirect Subsidiary of the Company. Except
as set forth in Section 2.1(c) of the Company Disclosure Schedule, neither the
Company nor any of its Subsidiaries owns any equity or similar interest in, or
any interest convertible into or exchangeable or exercisable for, directly or
indirectly, any equity or similar interest in, any Person.

         2.2 CERTIFICATE OF INCORPORATION AND BY-LAWS. The Company has
heretofore furnished to Parent a complete and correct copy of each of its and
each of its Subsidiaries' Certificates of Incorporation and by-laws or
equivalent organizational documents, as amended or restated to the date hereof.
Such Certificates of Incorporation and by-laws, as amended, and equivalent
organizational documents of the Company and each of its Subsidiaries are in full
force

                                       11
<PAGE>   17


and effect. Neither the Company nor any of its Subsidiaries is in violation of
any of the provisions of its Certificate of Incorporation or by-laws or
equivalent organizational documents.

         2.3      CAPITALIZATION.

                  (a) The authorized capital stock of the Company is 25,500,000
shares divided into 25,000,000 Company Common Shares and 300,000 shares of
Series A Preferred Stock and 200,000 shares of Series B Preferred Stock. As of
the date hereof, (i) 6,911,316 Company Common Shares were issued and outstanding
and 366,667 Company Preferred Shares were issued and outstanding; (ii) no
Company Common Shares were held in the treasury of the Company; (iii) 1,073,965
Company Common Shares were duly reserved for future issuance pursuant to stock
options granted and outstanding pursuant to the 1994 Plan, 1995 Plan and options
issued outside of any plan and (v) 2,939,443 Company Common Shares were duly
reserved for future issuance pursuant to issued and outstanding warrants to
purchase Company Common Shares. Except as set forth above, as of the date
hereof, no shares of voting or non-voting capital stock, other equity interests,
or other voting securities of the Company were issued, reserved for issuance or
outstanding. All options to purchase Company Common Shares were granted under
the Company's 1994 Plan or the Company's 1995 Plan, except for outstanding
options to purchase an aggregate of 400,035 Company Common Shares. Except as set
forth in Section 2.3(a) of the Company Disclosure Schedule, there are no
outstanding stock appreciation rights of the Company and no outstanding limited
stock appreciation rights or other rights to redeem for cash options or warrants
of Company. All outstanding shares of capital stock of the Company are, and all
shares which may be issued upon the exercise of stock options will be, when
issued, duly authorized, validly issued, fully paid and nonassessable and not
subject to preemptive rights. There are no bonds, debentures, notes or other
indebtedness of the Company with voting rights (or convertible into, or
exchangeable for, securities with voting rights) on any matters on which
stockholders of the Company may vote.

                  (b) Section 2.3(b) of the Company Disclosure Schedule sets
forth the number of authorized and outstanding shares of capital stock and the
names of the beneficial owners of such capital stock of each of the Company's
Subsidiaries as of August 11, 1999. Except as set forth in Section 2.3(b) of the
Company Disclosure Schedule, as of the date hereof, there are no outstanding
securities, options, warrants, calls, rights, commitments, agreements,
arrangements or undertakings of any kind (contingent or otherwise) to which the
Company or any of its Subsidiaries is a party or by which any of them is bound
obligating the Company or any of its Subsidiaries to issue, deliver or sell, or
cause to be issued, delivered or sold, additional shares of capital stock or
other voting securities of the Company or of any of its Subsidiaries or
obligating the Company or any of its Subsidiaries to issue, grant, extend or
enter into any such security, option, warrant, call, right, commitment,
agreement, arrangement or undertaking. There are no outstanding contractual
obligations of the Company or any of its Subsidiaries to repurchase, redeem or
otherwise acquire any shares of capital stock (or options to acquire any such
shares) of the Company or its Subsidiaries, except for the Series A Preferred
Stock and the Series B Preferred Stock. There are no agreements, arrangements or
commitments of any character (contingent or otherwise) pursuant to which any
person is or may be entitled or to cause the Company or any of its Subsidiaries
to file a registration statement under the Securities Act or

                                       12
<PAGE>   18


which otherwise relate to the registration of any securities of the Company,
except as disclosed in Section 2.3(b) of the Company Disclosure Schedule.

                  (c) There are no voting trusts, proxies or other agreements,
commitments or understandings of any character to which the Company or any of
its Subsidiaries is a party or by which the Company or any of its Subsidiaries
is bound with respect to the voting of any shares of capital stock of the
Company or any of its Subsidiaries, except for the Stockholder Agreements.

         2.4      AUTHORITY RELATIVE TO THIS AGREEMENT; REQUIRED VOTE.

                  (a) Subject to the approval of this Agreement by the Company's
stockholders, the Company has all necessary corporate power and authority to
execute and deliver this Agreement, and each instrument required to be executed
and delivered by it at the Closing, to perform its obligations hereunder and
thereunder and to consummate the transactions contemplated hereby and thereby.
The execution and delivery by the Company of this Agreement, the performance of
its obligations hereunder, and the consummation by the Company of the
transactions contemplated hereby, have been duly and validly authorized by all
corporate action and no other corporate proceedings on the part of the Company
are necessary to authorize this Agreement or to consummate the transactions so
contemplated (other than, with respect to the Merger, the approval and
authorization of this Agreement by votes of the holders of at least majority of
the outstanding Company Common Shares and the Company Preferred Shares (voting
together as one class), holders of at least sixty-six and two-thirds percent (66
2/3%) of the outstanding shares of the Company's Series A Preferred Stock
(voting as a single class) and holders of at least sixty-six and two-thirds
percent (66 2/3%) of the outstanding Series B Preferred Stock (voting as a
single class) in accordance with the applicable provisions of the DGCL and the
Company's Certificate of Incorporation and by-laws. This Agreement has been duly
and validly executed and delivered by the Company and, assuming the due
authorization, execution and delivery hereof and thereof by Parent and Merger
Sub, constitutes the legal, valid and binding obligation of the Company, subject
to the approval of the Company's stockholders and assuming Board of Directors'
approval by Parent and Merger Sub, in each case except to the extent the
enforcement thereof may be limited by (A) bankruptcy, insolvency,
reorganization, moratorium or other similar law now or hereafter in effect
relating to creditor's rights generally and (B) general principles of equity
(regardless of whether enforceability is considered in a proceeding in equity or
at law).

                  (b) The Board of Directors of the Company has directed that
this Agreement be submitted to the stockholders of the Company for their
approval and authorization. The affirmative votes of holders of at least a
majority of all outstanding Company Common Shares and Company Preferred Shares
(voting together as one class), holders of at least sixty-six and two-thirds
percent (66 2/3%) of all outstanding shares of Series A Preferred Stock (voting
as a single class), and holders of at least sixty-six and two-thirds percent (66
2/3%) of all outstanding shares of Series B Preferred Stock (voting as a single
class) are the only votes of the holders of any class or series of capital stock
of the Company necessary to approve and authorize this Agreement, the Merger,
the Related Agreements and the other transactions contemplated hereby and
thereby. The holders of the Company Common Shares and Company Preferred Shares
that

                                       13
<PAGE>   19


are parties to the Stockholder Agreements beneficially own and have the right to
vote, in the aggregate, approximately 34% of the total issued and outstanding
Company Common Shares and 82% of the total issued and outstanding Company
Preferred Shares.

         2.5      NO CONFLICT; REQUIRED FILINGS AND CONSENTS.

                  (a) The execution and delivery by the Company of this
Agreement or any instrument required by this Agreement to be executed and
delivered by the Company or any of its Subsidiaries at the Closing do not, and
the performance by the Company or any of its Subsidiaries of their obligations
under this Agreement or any instrument required by this Agreement to be executed
and delivered by the Company or any of its Subsidiaries at the Closing, shall
not, (i) conflict with or violate the Certificate of Incorporation or by-laws or
equivalent organizational documents of the Company or any of its Subsidiaries,
(ii) conflict with or violate any Law, Regulation or Order in each case
applicable to the Company or any of its Subsidiaries or by which its or any of
their respective properties is bound or affected, or (iii) result in any breach
or violation of or constitute a default (or an event that with notice or lapse
of time or both would become a default) under, or impair the Company's or any of
its Subsidiaries' rights or alter the rights or obligations of any third party
under, or give to others any rights of termination, amendment, acceleration or
cancellation of, or result in the creation of a Lien or encumbrance on any of
the properties or assets of the Company or any of its Subsidiaries pursuant to,
any note, bond, mortgage, indenture, contract, agreement, lease, license,
permit, franchise or other instrument or obligation to which the Company or any
of its Subsidiaries is a party or by which the Company or any of its
Subsidiaries or its or any of their respective properties is bound or affected,
except (A) as set forth in Section 2.5(a) of the Company Disclosure Schedule or
(B) in the case of clause (ii) or (iii) above, for any such conflicts, breaches,
violations, defaults or other occurrences that would not (x) individually, or in
the aggregate, have a Material Adverse Effect or (y) prevent or materially
impair or delay the consummation of the Merger.

                  (b) The execution and delivery by the Company of this
Agreement or any instrument required by this Agreement to be executed and
delivered by the Company or any of its Subsidiaries at Closing do not, and the
performance by the Company or any of its Subsidiaries of their obligations under
this Agreement and any instrument required by this Agreement to be executed and
delivered by the Company or any of its Subsidiaries at Closing, shall not,
require the Company or any of its Subsidiaries to obtain any consent or waiver
of any Person or the consent, approval, authorization or action by, license,
waiver, qualification, Order or Permit, observe any waiting period imposed by,
or make any filing with or notification to, any Court or Governmental Authority,
domestic or foreign, except for (A) valid approval of the Agreement by the
Company's stockholders, which approval has or will be obtained prior to the
Effective Time, (B) compliance with applicable requirements, if any, of the
Securities Act, the Securities Exchange Act of 1934, as amended (the "Exchange
Act"), state securities laws ("Blue Sky Laws"), (C) the filing of this Agreement
or (D) other documents as required by applicable provisions of the DGCL and such
other third party consents, approvals, authorization, licenses, waivers,
qualifications, Orders or Permits set forth in Section 2.5(a) of the Company
Disclosure Schedule.

                                       14
<PAGE>   20


                  2.6 MATERIAL AGREEMENTS. Section 2.6 of the Company Disclosure
Schedule sets forth a true and complete list of all contracts, licenses,
agreements, permits and instruments to which the Company or any of its
Subsidiaries is a party or by which any of them or any of their properties or
assets may be bound which is material to the Company and/or its Subsidiaries and
including without limitation all agreements pursuant to which the Company or any
of its Subsidiaries has granted exclusive rights or have terms of one year or
longer (collectively, the "Material Agreements"). Complete copies of all
Material Agreements have been provided by the Company to Parent and no oral
Material Agreements exist. Each such Material Agreement is in full force and
effect, is a valid and binding obligation of the Company or such Subsidiary and
is enforceable against the Company or such Subsidiary in accordance with its
terms and the Company does not have Knowledge that any Material Agreement is not
a valid and binding agreement of the other parties thereto. Except as set forth
in Section 2.6 of the Company Disclosure Schedule, each Material Agreement is
enforceable in each case except to the extent the enforcement thereof may be
limited by (A) bankruptcy, insolvency, reorganization, moratorium or other
similar law now or hereafter in effect relating to creditors' rights generally
and (B) general principles of equity (regardless of whether enforceability is
considered in a proceeding in equity or at law). Except as set forth on Section
2.6 of the Company Disclosure Schedule, no condition exists or, to the Company's
Knowledge, event has occurred which (whether with or without notice or lapse of
time or both, or the happening or occurrence of any other event) would result in
a loss of rights or an acceleration of an obligation or result in the creation
of any Lien thereunder or pursuant thereto, or would constitute a default by the
Company or any of its Subsidiaries or, to the Company's Knowledge, any other
party thereto under, or result in a right in termination of, any Material
Agreement. The Company and its Subsidiaries are in compliance in all material
respects with the terms of the Company Approvals, except as set forth in Section
2.6 of the Company Disclosure Schedule. The continuation, validity,
enforceability and effectiveness of each Material Agreement will not be affected
by the consummation of the transactions contemplated by this Agreement, except
as set forth on Section 2.5(a) of the Company Disclosure Schedule. Furthermore,
no party to a Material Agreement has repudiated any provision thereof and
communicated such repudiation to the Company, and there are no negotiations
pending or in progress to revise any material terms of any Material Agreement.

         2.7 COMPLIANCE WITH AGREEMENTS AND LAW. Neither the Company nor any of
its Subsidiaries is in conflict with, or in default or violation of, any Law,
Regulation or Order applicable to the Company or such Subsidiary or by which its
or any of their respective properties is bound or affected. The Company has all
requisite licenses, permits, certificates, authorizations and approvals
including environmental, health and safety and employee health and safety
permits, from foreign, federal, state and local authorities necessary to conduct
the business as currently conducted (collectively, the "Permits"), all of which
Permits are set forth in Section 2.7 of the Company Disclosure Schedule. All of
the Permits identified in Section 2.7 of the Company Disclosure Schedule are in
full force and effect, and to the Company's Knowledge, no party thereto is in
default under any of such Permits and no event has occurred and no condition
exists which, with the giving of notice, the passage of time, or both, would
constitute a default thereunder. No action or claim is pending or, to the
Company's Knowledge, threatened to revoke or terminate any Permit identified in
Section 2.7 of the Company Disclosure Schedule.

                                       15
<PAGE>   21


Except as set forth in Section 2.7 of the Company Disclosure Schedule, the
Company is not nor has it been in violation of any Law, rule, Regulation,
ordinance or court or administrative order (including, without limitation, those
relating to building, zoning, environmental, disposal or hazardous substances,
land use, health and safety and employee health and safety matters). Except as
set forth on Section 2.7 of the Company Disclosure Schedule, neither the Company
nor its Subsidiaries has received any notice or communication from any foreign,
federal, state or local governmental or regulatory authority or otherwise of any
such violation and, to the Company's Knowledge, no such notice or communication
is threatened. The Company's and, to the Company's Knowledge, its vendors'
production and documentation procedures are in all material respects consistent
and in compliance with Good Manufacturing Practices as prescribed by the United
States Food and Drug Administration as applicable to a supplier to the
pharmaceutical industry.

         2.8      SEC FILINGS; FINANCIAL STATEMENTS.

                  (a) The Company has previously furnished or made available to
Parent true, complete and accurate copies, as amended or supplemented, of its
(a) Annual Reports on Form 10-KSB for the calendar years ended December 31,
1996, 1997 and 1998 and Quarterly Report on Form 10-QSB for the quarter ended
March 31, 1999, as filed with the Securities and Exchange Commission (the
"SEC"), (b) proxy statements relating to all meetings of its stockholders
(whether annual or special) since January 1, 1998 and (c) all other reports or
registration statements, other than Registration Statements on Form S-8, filed
by the Company with the SEC since January 1, 1998. Except as set forth in
Section 2.8 of the Company Disclosure Schedule, the Company has timely filed all
reports and schedules required to be filed with the SEC (collectively, the
"Company SEC Reports") required to be filed by it pursuant to the Exchange Act
and the SEC Regulations promulgated thereunder. Except as set forth in Section
2.8 of the Company Disclosure Schedule, the Company SEC Reports were prepared in
accordance, and complied as of their respective dates in all material respects,
with the requirements of the Exchange Act and the SEC Regulations promulgated
thereunder and did not as of their respective dates (or if amended by a filing
prior to the date hereof, then as of the date of such amendment) contain any
untrue statement of a material fact or omit to state a material fact required to
be stated therein or necessary in order to make the statements therein, in the
light of the circumstances under which they were made, not misleading, except to
the extent superseded by a Company SEC Report filed subsequently and prior to
the date hereof.

                  (b) Each of the consolidated financial statements (including,
in each case, any related notes thereto) contained in the Company SEC Reports
(i) complied in all material respects with applicable accounting requirements
and the published SEC Regulations with respect thereto, (ii) were prepared in
accordance with generally accepted accounting principles ("GAAP") applied on a
consistent basis throughout the periods involved (except as may be expressly
described in the notes thereto) and (iii) fairly present the consolidated
financial position of the Company and its Subsidiaries as of the respective
dates thereof and the consolidated results of its operations and cash flows for
the periods indicated, except that the unaudited interim financial statements
included in the Company's Form 10-QSB reports were or

                                       16
<PAGE>   22


are subject to normal year-end adjustments that are neither individually or in
the aggregate material.

         2.9      ABSENCE OF CERTAIN CHANGES OR EVENTS.

                  (a) Since December 31, 1998, the Company and its Subsidiaries
have conducted their businesses only in the ordinary and usual course and in a
manner consistent with past practice and, since such date, there has not been
any change, event, development or circumstance affecting the Company or any of
its Subsidiaries which, individually or in the aggregate, has or is reasonably
likely to have, a Material Adverse Effect.

                  (b) Since December 31, 1998, there has not been any change by
the Company in its accounting methods, principles or practices, any revaluation
by the Company of any of its assets, including, writing down the value of
inventory or writing off notes or accounts receivable other than in the ordinary
course of business, and there has not been any other action or event, and
neither the Company nor any of its Subsidiaries has agreed in writing or
otherwise to take any other action, that would have required the consent of
Parent pursuant to Section 4.1 had such action or event occurred after the date
hereof and prior to the Effective Time, or any condition, event or occurrence
which could reasonably be expected to prevent, hinder or materially delay the
ability of the Company to consummate the transactions contemplated by this
Agreement.

         2.10 NO UNDISCLOSED LIABILITIES. Neither the Company nor any of its
Subsidiaries has any liabilities or obligations of any nature (whether absolute,
accrued, fixed, contingent or otherwise), except (a) liabilities or obligations
reflected in the Company SEC Reports through the date of the filing of the
Company's Quarterly Report on Form 10-QSB in respect of the fiscal quarter
ending March 31, 1999, (b) liabilities or obligations incurred in the ordinary
course of business consistent with past practice since March 31, 1999 which are
not, and will not have, individually or in the aggregate, a Material Adverse
Effect on the Company and (c) liabilities or obligations which are not and will
not have, individually or in the aggregate, a Material Adverse Effect on the
Company.

         2.11     ABSENCE OF LITIGATION.

         Except as described in Section 2.11 of the Company Disclosure Schedule,
there is no Litigation pending or, to the Company's Knowledge, threatened
against the Company or any Subsidiary of the Company, that would be or have a
Material Adverse Effect on the Company. Neither the Company nor any of its
Subsidiaries is subject to any outstanding Claim or Order which, individually or
in the aggregate, has, or in the future might have, a Material Adverse Effect or
would prevent, hinder or delay the Company from consummating the transactions
contemplated by this Agreement.

         2.12     EMPLOYEE BENEFIT PLANS.

                  (a) Section 2.12(a) of the Company Disclosure Schedule
contains a true and complete list of each deferred compensation, incentive
compensation, stock purchase, restricted stock option and other equity
compensation plan, "welfare" plan, fund or program (within the

                                       17
<PAGE>   23


meaning of Section 3(1) of the Employee Retirement Income Security Act of 1974,
as amended ("ERISA")); each "pension" plan, fund or program (within the meaning
of Section 3(2) of ERISA); and each other material employee benefit plan, fund,
program, agreement or arrangement, including but not limited to vacation plans,
cafeteria plans, educational assistance or reimbursement plans, spending account
plans (for medical expenses, dependent care expenses, or other expenses),
severance, golden parachute, termination, supplemental unemployment, plant
closing or similar benefits, active health or life or other post-employment
welfare or insurance plans, bonus or performance based compensation plans or
arrangements, supplemental executive retirement plans or other supplemental or
excess benefit plans in each case, that is sponsored, maintained or contributed
to or required to be contributed to by the Company or any entity, or any of its
Subsidiaries, any trade or business (whether or not incorporated) which is a
member of a controlled group or which is under common control with the Company
within the meaning of Section 414 of the Code or which could be deemed a "single
employer" within the meaning of Section 4001(b) of ERISA (an "ERISA Affiliate"),
or to which the Company or an ERISA Affiliate is a party, whether written or
oral, for the benefit of any officer, director, employee or former employee of
the Company or any of its ERISA Affiliates, whether or not such plan has been
terminated (the "Company Plans"). Except as set forth in Section 2.12(a) of the
Company Disclosure Schedule, there are no restrictions on the ability of the
Company, its Subsidiaries or any of its ERISA Affiliates to amend, modify or
terminate any Company Plan and each Company Plan is fully and readily assignable
and transferable by its sponsor to either the Parent or the Merger Sub.

                  (b) With respect to each Company Plan, the Company has
heretofore made available to Parent true and complete copies of the Company Plan
and any amendments thereto (or if the Company Plan is not a written Company
Plan, a description thereof), any related trust or other funding vehicle, the
summary plan description and any summaries of material modifications, the three
(3) most recent annual reports (with all schedules) or summaries required under
ERISA or the Code, the most recent audited financial statements and most recent
determination letter received from the Internal Revenue Service with respect to
each Company Plan intended to qualify under Section 401 of the Code.

                  (c) No material liability under Title IV or Section 302 of
ERISA has been incurred by the Company or any ERISA Affiliate that has not been
satisfied in full, and no condition exists that presents a material risk to the
Company or any ERISA Affiliate of incurring any such liability.

                  (d) No Company Plan is subject to Title IV of ERISA or Section
412 of the Code, nor is any Company Plan a "multiemployer pension plan", as
defined in Section 3(37) of ERISA, or subject to Section 302 of ERISA. No
Company Plan is a "single-employer plan under multiple controlled groups" as
described in Section 4063 of ERISA.

                  (e) Each Company Plan has been operated and administered in
all respects in accordance with its terms and applicable law, including ERISA
and the Code. There has been no "prohibited transaction," as such term is
defined in Section 406 of ERISA or Section 4975 of the Code, with respect to any
Company Plan; there are no claims pending (other than routine claims

                                       18
<PAGE>   24


for benefits) or, to the Company's Knowledge, threatened against any Company
Plan or against the assets of any Company Plan, nor are there any current or, to
the Company's Knowledge, threatened Liens on the assets of any Company Plan or
on the assets of the Company under any provision of ERISA. The Company and its
ERISA Affiliates have performed all obligations required to be performed by them
under, are not in default under or violation of, and have no Knowledge of any
default or violation by any other party with respect to, any of the Company
Plans. All contributions required to be made to any Company Plan under
applicable law or the terms of the respective Company Plan have been made on or
before their due dates and a reasonable amount has been accrued for
contributions to each Company Plan for the current plan years; except as
disclosed on Section 2.12(e) of the Company Disclosure Schedule, the transaction
contemplated herein will not directly or indirectly result in an increase of
benefits, acceleration of vesting or acceleration of timing for payment of any
benefit to any participant or beneficiary under any Company Plan.

                  (f) Each Company Plan intended to be "qualified" within the
meaning of Section 401(a) of the Code and the trusts maintained thereunder that
are intended to be exempt from taxation under Section 501(a) of the Code have
received a favorable determination or opinion letter indicating that they are so
qualified, and no event has occurred since the date of said letter(s) that will
adversely affect the qualification of such Company Plan.

                  (g) Except as set forth in Section 2.12(g) of the Company
Disclosure Schedule, no Company Plan or written or oral agreement provides
medical, surgical, hospitalization, death or similar benefits (whether or not
insured) for directors, employees or former employees of the Company or any of
its Subsidiaries or ERISA Affiliates for periods extending beyond their
retirement or other termination of service, other than (i) coverage mandated by
applicable Law, (ii) death benefits under any "pension plan" or (iii) benefits
the full cost of which is borne by the current or former employee (or his
beneficiary).

                  (h) No amounts payable under any Company Plan will fail to be
deductible for federal income Tax purposes by virtue of Section 280G of the
Code.

                  (i) Except as set forth in Section 2.12(i) of the Company
Disclosure Schedule, the execution, delivery and performance of, and
consummation of the transactions contemplated by, this Agreement, or the
Stockholder Agreements will not (i) entitle any current or former employee or
officer of the Company or any ERISA Affiliate to severance pay, unemployment
compensation or any other payment, except as expressly provided in this
Agreement, (ii) accelerate the time of payment or vesting, or increase the
amount of compensation due any such employee or officer, or (iii) assuming the
Parent takes the action specified in Section 5.5(a), accelerate the vesting of
any stock option or of any shares of restricted stock.

                  (j) Except as would not be material in any respect to the
Company, there are no pending or, to the Company's Knowledge, threatened or
anticipated claims by or on behalf of any Company Plan, by any employee or
beneficiary covered under any such Company Plan or otherwise involving any such
Company Plan (other than routine claims for benefits).

                                       19
<PAGE>   25


                  (k) Section 2.12(k) of the Company Disclosure Schedule sets
forth a true and complete list of each current or former employee, officer,
director or investor of the Company or any of its Subsidiaries who holds, as of
the date hereof, any option, warrant or other right to purchase Company Common
Shares or Company Preferred Shares, if any, together with the number of Company
Common Shares or Company Preferred Shares, if any, subject to such option,
warrant or right, the date of grant or issuance of such option, warrant or
right, the extent to which such option, warrant or right is vested and/or
exercisable, the exercise price of such option, warrant or right, whether such
option is intended to qualify as an incentive stock option within the meaning of
Section 422(b) of the Code, and the expiration date of each such option, warrant
and right. Section 2.12(k) of the Company Disclosure Schedule also sets forth
the total number of such options, warrants and rights. True and complete copies
of each agreement (including all amendments and modifications thereto) between
the Company and each holder of such options, warrants and rights relating to the
same have been furnished to Parent and are listed in Section 2.12(k) of the
Company Disclosure Schedule.

         2.13     EMPLOYMENT AND LABOR MATTERS.

                  (a) Section 2.13(a) of the Company Disclosure Schedule
identifies all employees and consultants employed or engaged by the Company and
sets forth each such individual's rate of pay or annual compensation (and the
portions thereof attributable to salary and bonuses, respectively), job title
and date of hire. Except as set forth in Section 2.13(a) of the Company
Disclosure Schedule, there are no employment, consulting, severance pay,
continuation pay, termination or indemnification agreement or other similar
agreements of any nature (whether in writing or not) between the Company or any
Subsidiary and any current or former stockholder, officer, director, employee,
or any consultant. Except as set forth in Section 2.13(a), Section 2.12(i) or
Section 2.12(g) of the Company Disclosure Schedule, no individual will accrue or
receive additional benefits, service or accelerated rights to payments under any
Company Plan or any of the agreements set forth in Section 2.13(a) of the
Company Disclosure Schedule, including the right to receive any parachute
payment, as defined in Section 280G of the Code, or become entitled to
severance, termination allowance or similar payments as a result of the
transaction contemplated herein that could result in the payment of any such
benefits or payments. Neither the Company nor any Subsidiary is delinquent in
payments to any of its employees or consultants for any wages, salaries,
commissions, bonuses or other compensation for any services. None of the
Company's or any Subsidiary's employment policies or practices is currently
being audited or investigated by any Governmental Authority. There are no
pending, or to the Company's Knowledge, threatened claims, charges, actions,
lawsuits or proceedings alleging claims against the Company or any Subsidiary
brought by or on behalf of any employee or other individual or any Governmental
Authority with respect to employment practices, and to the Company's Knowledge,
no facts or circumstances exist that could give rise to any such claims,
charges, actions, lawsuits or proceedings.

                  (b) Except as set forth in Section 2.13(b) of the Company
Disclosure Schedule, there are no controversies pending or, to the Company's
Knowledge, threatened between the Company or any of its Subsidiaries and any of
their respective employees and employee relations are, in general, considered to
be good; neither the Company nor any of its

                                       20
<PAGE>   26


Subsidiaries is a party to any collective bargaining agreement or other labor
union contract applicable to persons employed by the Company or its Subsidiaries
nor are there any activities or proceedings of any labor union or by any
employees to organize any such employees of the Company or any of its
Subsidiaries; during the past five years there have been no strikes, slowdowns,
work stoppages, lockouts, or threats thereof, by or with respect to any
employees of the Company or any of its Subsidiaries. The Company does not have
nor at the Closing will the Company have any obligation under the Worker
Adjustment and Retraining Notification Act (the "WARN Act"). The Company and
each of its Subsidiaries is in material compliance with all applicable
provisions of applicable state, local, federal and foreign employment, wage and
hour, labor and other applicable laws.

         2.14 REGISTRATION STATEMENT; PROXY STATEMENT/PROSPECTUS. The
information supplied by the Company or required to be supplied by the Company
(except to the extent revised or superseded by amendments or supplements) for
inclusion in the registration statement on Form S-4, or any amendment or
supplement thereto, pursuant to which the shares of Parent Common Stock to be
issued in the Merger will be registered with the SEC (including any amendments
or supplements, the "Registration Statement") shall not, at the time such
documents are filed and at the time the Registration Statement (including any
amendments or supplements thereto) is declared effective by the SEC, contain any
untrue statement of a material fact or omit to state any material fact required
to be stated therein or necessary in order to make the statements therein, in
light of the circumstances under which they were made, not misleading. The
information supplied by the Company for inclusion in the proxy
statement/prospectus to be sent to the stockholders of the Company in connection
with the meeting of the stockholders of the Company to consider the Merger (the
"Company Stockholders' Meeting") (such proxy statement/prospectus, as amended or
supplemented, the "Proxy Statement") will not, on the date the Proxy Statement
(or any amendment thereof or supplement thereto) is first mailed to the
stockholders of the Company, at the time of the Company Stockholders' Meeting
and at the Effective Time, contain any statement which, at such time and in
light of the circumstances under which it shall be made, is false or misleading
with respect to any material fact, or omit to state any material fact necessary
in order to make the statements made therein not false or misleading in light of
the circumstances under which they were made, or omit to state any material fact
necessary to correct any statement in any earlier communication with respect to
the solicitation of proxies for the Company Stockholders' Meeting which has
become materially false or misleading. If at any time prior to the Effective
Time any event relating to the Company or any of its respective Affiliates,
officers or directors is discovered by the Company which should be set forth in
an amendment to the Registration Statement or an amendment or supplement to the
Proxy Statement, the Company shall promptly inform Parent and Merger Sub.
Notwithstanding the foregoing, the Company makes no representation or warranty
with respect to any information supplied by Parent or Merger Sub which is
contained in any of the foregoing documents. The Proxy Statement shall comply as
to form in all material respects with the requirements of the Exchange Act and
the Regulations promulgated thereunder.

         2.15 ABSENCE OF RESTRICTIONS ON BUSINESS ACTIVITIES. Except as set
forth in Section 2.15 of the Company Disclosure Schedule or as set forth in this
Agreement, there is no Material Agreement or Order binding upon the Company or
any of its Subsidiaries or any of their

                                       21
<PAGE>   27


properties which has had or could reasonably be expected to have the effect of
prohibiting or materially impairing any business practice of the Company or any
of its Subsidiaries or the conduct of business by the Company or any of its
Subsidiaries as currently conducted or as proposed to be conducted by the
Company or any of its Subsidiaries. Neither the Company nor any of its
Subsidiaries is subject to any non-competition or similar restriction on their
respective businesses. Neither the Company nor any of its Subsidiaries has at
any time entered into, or agreed to enter into, any interest rate swaps, caps,
floors or option agreements or any other interest rate risk management
arrangement or foreign exchange contracts.

         2.16 TITLE TO ASSETS; LEASES. Except as described in Section 2.16 of
the Company Disclosure Schedule, the Company owns no real property. Section 2.16
of the Company Disclosure Statement sets forth a true and complete list of all
real property leased by the Company or any of its Subsidiaries, and the
aggregate monthly rental or other fee payable under such lease. Except as
described in Section 2.16 of the Company Disclosure Schedule, the Company and
each of its Subsidiaries has good and marketable title to all of their
properties and assets, free and clear of all Liens, charges and encumbrances,
except Liens for Taxes (as defined below) not yet due and payable and such Liens
or other imperfections of title, if any, as do not materially detract from the
value of or interfere with the present use of the property affected thereby. All
leases pursuant to which the Company or any of its Subsidiaries lease real or
personal property from others are valid and effective in accordance with their
respective terms, and there is not, under any of such leases, any existing
material default or event of material default (or event which with notice or
lapse of time, or both, would constitute a material default and in respect of
which the Company or such Subsidiary has not taken adequate steps to prevent
such a default from occurring or to cure such default) by the Company or its
Subsidiaries or, to the Company's Knowledge, any third party.

         The Company or its Subsidiaries, individually or together, have good
and marketable title to or a valid leasehold interest in all of the properties
and assets that are necessary to the conduct of the business of the Company and
its Subsidiaries as it is currently being conducted, including all of the
properties and assets reflected in the Company's consolidated balance sheet as
of December 31, 1998, which was filed with the SEC as part of its report on Form
10-KSB, other than any such properties or assets that have been sold or
otherwise disposed of in the ordinary course of business since December 31,
1998.

         2.17 TAXES. For purposes of this Agreement, "Tax" or "Taxes" shall mean
taxes and governmental impositions of any kind in the nature of (or similar to)
taxes, payable to any federal, state, local or foreign taxing authority,
including but not limited to those on or measured by or referred to as income,
franchise, profits, gross receipts, capital ad valorem, custom duties,
alternative or add-on minimum taxes, estimated, environmental, disability,
registration, value added, sales, use, service, real or personal property,
capital stock, license, payroll, withholding, employment, social security,
workers' compensation, unemployment compensation, utility, severance,
production, excise, stamp, occupation, premiums, windfall profits, transfer and
gains taxes, and interest, penalties and additions to tax imposed with respect
thereto; and "Tax Returns" shall mean returns, reports and information
statements, including any schedule or attachment thereto, with respect to Taxes
required to be filed with the Internal Revenue Service

                                       22
<PAGE>   28


or any other governmental or taxing authority or agency, domestic or foreign,
including consolidated, combined and unitary tax returns. Except as set forth in
Section 2.17 of the Company Disclosure Schedule:

                  (a) All federal, state, local and foreign Tax Returns required
to be filed (taking into account extensions) by or on behalf of the Company,
each of its Subsidiaries, and each affiliated, combined, consolidated or unitary
group of which the Company or any of its Subsidiaries is or has been a member
have been timely filed, and all such Tax Returns are true, complete and correct,
except to the extent that any failure to file or any inaccuracies in filed Tax
Returns would not, individually or in the aggregate, have a Material Adverse
Effect.

                  (b) All Taxes payable by or with respect to the Company and
each of its Subsidiaries have been timely paid, or are adequately reserved for
(other than a reserve for deferred Taxes established to reflect timing
differences between book and Tax treatment) in accordance with GAAP on the
respective company's Balance Sheet, except to the extent that such amount would
not, individually or in the aggregate, have a Material Adverse Effect. No
deficiencies for any Taxes have been proposed, asserted or assessed either
orally or in writing against the Company or any of its Subsidiaries that are not
adequately reserved for in accordance with GAAP on the respective company's
Balance Sheet. All assessments for Taxes due and owing by or with respect to the
Company and each of its Subsidiaries with respect to completed and settled
examinations or concluded litigation have been paid. Neither the Company nor any
of its Subsidiaries has incurred a Tax liability from the date of the latest
Balance Sheet other than a Tax liability in the ordinary course of business.

                  (c) Neither the Company nor any of its Subsidiaries has
requested, or been granted any waiver of any federal, state, local or foreign
statute of limitations with respect to, or any extension of a period for the
assessment of, any Tax. No extension or waiver of time within which to file any
Tax Return of, or applicable to, the Company or any of its Subsidiaries has been
granted or requested, except as set forth in Section 2.17 of the Company
Disclosure Schedule which has not since expired.

                  (d) Other than with respect to its Subsidiaries the Company is
not and has never been (nor does the Company have any liability for unpaid Taxes
because it once was) a member of an affiliated, consolidated, combined or
unitary group, and neither the Company nor any of its Subsidiaries is a party to
any Tax allocation or sharing agreement or is liable for the Taxes of any other
party, as transferee or successor, by contract, or otherwise.

                  (e) Prior to the date hereof, the Company has provided Parent
with written schedules setting forth the taxable years of the Company for which
the statutes of limitations with respect to foreign, federal and material state
income Taxes have not expired and with respect to foreign, federal and material
state income Taxes, those years for which examinations have been completed and
those years for which examinations are presently being conducted.

                  (f) The Company is not presently and has not been a "foreign
investment company" as such term is defined in Section 1246(b) of the Code.

                                       23
<PAGE>   29


                  (g) The Company is not presently and has not been a "passive
foreign investment company" as such term is defined in Section 1297(a) of the
Code.

                  (h) The Company is not presently and has not been at any time
during the last five years a "controlled foreign corporation" as such term is
defined in Section 957(a) of the Code.

                  (i) The Company and its Subsidiaries have not made any
payments, are not obligated to make any payments, and are not a party to any
agreements that under any circumstances could obligate any of them to make any
payments that will not be deductible under Section 280G of the Code.

                  (j) No unsatisfied deficiency, delinquency or default for any
Tax has been claimed, proposed or assessed against or with respect to the
Company or any Subsidiary, nor has the Company or any Subsidiary received notice
of any such deficiency, delinquency or default which, in any such case, may have
a Material Adverse Effect.

                  (k) The Company has not been a United States real property
holding corporation within the meaning of Section 897(c)(2) of the Code during
the applicable period specified in Section 897(c)(1)(A)(ii) of the Code.

                  (l) The Company and each of its Subsidiaries have complied
with all applicable Laws relating to the payment and withholding of Taxes
(including, without limitation, withholding of Taxes pursuant to Sections 1441,
1442 and 3406 of the Code or similar provisions under any foreign Laws) and
have, within the time and in the manner required by Law, withheld from employee
wages and paid over to the proper Governmental Authorities all amounts required
to be so withheld and paid over under all applicable Laws.

                  (m) Section 2.17(m) of the Company Disclosure Schedule sets
forth: (i) the net operating loss ("NOL") and (ii) capital loss carry forwards
for foreign, federal income Tax purposes of each of the Company and its
Subsidiaries through the taxable year ended December 31, 1998.

                  (n) Except as described in Section 2.17(n) of the Company
Disclosure Schedule, the NOLs of the Company or any Subsidiary are not, as of
the date hereof, subject to Section 382 or 269 of the Code, Treasury Regulation
Section 1.1502-21T(c), or any similar provisions or regulations otherwise
limiting the use of the NOLs of the Company or any of its Subsidiaries.

                  (o) No property of the Company or any of its Subsidiaries is
"tax-exempt use property" as such term is defined in Section 168 of the Code.

                  (p) Neither the Company nor any of its Subsidiaries has made
an election under Section 341(f) of the Code.

                                       24
<PAGE>   30


         2.18 ENVIRONMENTAL MATTERS. Except as described in Section 2.18 of the
Company Disclosure Schedule:

                  (a) the Company and its Subsidiaries are and have been in
         compliance in all material respects with all applicable Environmental
         Laws;

                  (b) the Company and its Subsidiaries have obtained all Permits
         relating to the business required by any applicable Environmental Law
         and all environmental permits relating to the business of the Company
         and all such permits are in full force and effect in all material
         respects; the environmental permits do not materially limit or affect
         the processes, methods, capacity or operating hours of the persons
         carrying on the business of the Company as it is currently carried on;

                  (c) neither the Company nor any of its Subsidiaries has, and
         the Company has no Knowledge of any other Person who has, caused any
         unlawful or improper release, threatened release or disposal of any
         Hazardous Material at any properties or facilities previously or
         currently owned, leased or occupied by the Company or its Subsidiaries;

                  (d) the Company has no Knowledge that any of its or its
         Subsidiaries' properties or facilities are adversely affected by any
         release, threatened release or disposal of a Hazardous Material
         originating or emanating from any other property;

                  (e) neither the Company nor any of its Subsidiaries (i) has
         any liability for response or corrective action, natural resources
         damage, or any other harm pursuant to any Environmental Law, (ii) is
         subject to, has notice or Knowledge of, or is required to give any
         notice of any Environmental Claim involving an allegation against the
         Company or any Subsidiary or any properties or facilities of the
         Company or (iii) has Knowledge of any condition or occurrence which
         could reasonably be expected to form the basis of an Environmental
         Claim against the Company, any of its Subsidiaries or any of their
         properties or facilities;

                  (f) the Company and its Subsidiaries' properties and
         facilities are not subject to any, and the Company has no Knowledge of
         any, imminent restriction on the ownership, occupancy, use or
         transferability of their properties and facilities arising from any (i)
         Environmental Law or (ii) release, threatened release or disposal of
         any Hazardous Material; and

                  (g) there is no Environmental Claim pending, or, to the
         Company's Knowledge, threatened, against the Company or, to the
         Company's Knowledge, against any Person whose liability for any
         Environmental Claim the Company has or may have retained or assumed
         either contractually or by operation of law. No material capital
         expenditure is currently required for the Company in relation to
         environmental matters in order to comply with, extend, renew or obtain
         any environmental permit or comply with Environmental Laws. Copies of
         all environmental audits and other assessments, reviews and reports
         have been previously provided to the Parent.

                                       25
<PAGE>   31


         2.19     INTELLECTUAL PROPERTY.

                  (a) Section 2.19(a) of the Company Disclosure Schedule sets
forth a true, correct and complete list of all United States and foreign (i)
patents and patent applications, (ii) registered and unregistered trademarks and
trademark applications (including material Internet domain name registrations),
(iii) service marks and service mark applications, (iv) trade names, (v)
copyright registrations, and copyright applications, and (vi) licenses presently
used by the Company and/or its Subsidiaries, indicating for each, the applicable
jurisdiction, registration number (or applicable number), and date issued or
filed, as applicable with respect to (i), (ii), (iii), and (v) above and
including the terms of such licenses (all of which, together with patent rights,
trade secrets, confidential business information, formulas, processes, invention
records, procedures, research and development activity reports, laboratory
notebooks, copyrights, license rights and trademark rights which relate to or
are used or held for use in connection with the business of the Company, are
collectively referred to as, the "Intellectual Property Rights"). Copies of such
licenses have been previously provided to Parent. To the Company's Knowledge,
the Intellectual Property Rights are sufficient for the conduct of the Company's
business as presently conducted and as proposed to be conducted.

                  (b) Section 2.19(b) of the Company Disclosure Schedule sets
forth a true, correct and complete list, and where appropriate, a description of
all Intellectual Property Rights set forth in Section 2.19(a) of the Company
Disclosure Schedule to which neither the Company's nor its Subsidiary's rights
are exclusive, excluding all Intellectual Property Rights which the Company has
the right to use under a shrinkwrap or similar mass marketing license. Except as
otherwise disclosed in Section 2.19(b) of the Company Disclosure Schedule and
excluding all Intellectual Property Rights subject to a shrinkwrap or similar
mass marketing license, the Company exclusively owns or has the exclusive right
to use all of the Intellectual Property Rights listed in Section 2.19(a) of the
Company Disclosure Schedule. The Company does not believe it is or will be
necessary to utilize any inventions of any of its employees or consultants (or
individuals it currently intends to hire) made prior to their employment by the
Company.

                  (c) All trademarks, patents and copyrights are currently in
compliance with all legal requirements (including the timely post-registration
filing of affidavits of use and incontestability and renewal applications with
respect to trademarks, and the payment of filing, examination and maintenance
fees and proof of working or use with respect to patents), are, to the Company's
Knowledge, valid and enforceable. Section 2.19(c) of the Company Disclosure
Schedule sets forth the maintenance fees due on or before December 31, 1999. No
trademark has been or is now involved in any cancellation and, to the Company's
Knowledge and its Subsidiaries, no such action is threatened with respect to any
of the trademarks. Except as disclosed set forth on Section 2.19(c) of the
Company Disclosure Schedule, no patent has been or is now involved in any
interference, reissue, re-examination or opposing proceeding. To the Company's
Knowledge, there are no potentially conflicting trademarks or potentially
interfering patents of any third party. The Company has made available to Parent
all opinions, reviews, assessments or analyses (whether written or oral) of the
Company's ability to use patents whether owned or licensed.

                                       26
<PAGE>   32


                  (d) Except as would not be materially adverse to the Company
and each of its Subsidiaries:

                           (i) The Company or a Subsidiary of the Company owns
         free and clear of all Liens, all owned Intellectual Property Rights
         used in the Company's business, and has a valid and enforceable right
         to use in accordance with the applicable license agreement, if any, all
         of the Intellectual Property Rights licensed to the Company and used in
         the Company's business;

                           (ii) The Company and each of its Subsidiaries have
         taken reasonable steps to protect and preserve the Intellectual
         Property Rights which the Company or such Subsidiary owns;

                           (iii) The conduct of the Company's and its
         Subsidiaries' businesses as currently conducted or contemplated does
         not, to the Company's Knowledge, infringe upon any intellectual
         property rights owned or controlled by any third party;

                           (iv) There is no Litigation pending or, to the
         Company's Knowledge, threatened nor has Company received any written
         communication of, and the Company has no Knowledge of any basis for a
         claim against it (a) alleging that the Company's activities, products,
         publications or the conduct of its businesses or that of any of its
         Subsidiaries infringes upon, violates, or constitutes the unauthorized
         use of the intellectual property rights of any third party or (b)
         challenging the ownership, use, validity or enforceability of any
         Intellectual Property Rights of the Company or any of its Subsidiaries;

                           (v) To the Company's Knowledge, no third party is
         misappropriating, infringing, diluting, or violating any Intellectual
         Property Rights owned by the Company or any of its Subsidiaries and no
         such claims have been brought against any third party by the Company or
         any of its Subsidiaries, and the Company has not knowingly
         misappropriated the trade secrets of any third party;

                           (vi) Except as set forth in Section 2.5(a) of the
         Company Disclosure Schedule, the execution, delivery and performance by
         the Company of this Agreement, and the consummation of the transactions
         contemplated hereby will not result in the loss or impairment of or
         give rise to any right of any third party to terminate any of the
         Company's or any of its Subsidiaries' right to own any of the
         Intellectual Property Rights owned by the Company or any of its
         Subsidiaries or to use any Intellectual Property Rights licensed to the
         Company or any of its Subsidiaries pursuant to the license Agreements,
         nor require the consent of any Governmental Authority or third party in
         respect of any such Intellectual Property Rights;

                  (e) All trademarks and trademark applications of the Company
and its Subsidiaries have been in continuous use by the Company or its
Subsidiaries. To the Company's Knowledge (i) there has been no prior use of such
trademarks by any third party which would confer upon said third party superior
rights in such trademarks, and (ii) the registered trademarks

                                       27
<PAGE>   33


have been continuously used in the form appearing in, and in connection with the
goods and services listed in, their respective registration certificates.

                  (f) The Company and/or its Subsidiaries have taken all
reasonable steps in accordance with normal industry practice to protect the
Company's and its Subsidiaries' rights in confidential information and trade
secrets of the Company and/or its Subsidiaries. Without limiting the foregoing
and except as would not be materially adverse to the Company, the Company and
its Subsidiaries have and enforce a policy of requiring each employee,
consultant and contractor to execute proprietary information, confidentiality
and assignment agreements substantially consistent with the Company's standard
forms thereof. Except under confidentiality obligations, to the Knowledge of the
Company, there has been no material disclosure by the Company or any Subsidiary
of the Company of material confidential information or trade secrets.

                  (g) The Company has undertaken the review and assessment of
the business and operations of itself and its Subsidiaries that could be
adversely affected by its or their failure to be Year 2000 Compliant. The
Company has requested certification from the outside vendors listed in the
Company Disclosure Schedule that the computer system, hardware, software,
database, device and/or equipment purchased from each such vendor and used
internally by the Company, or used by such vendor in the performance of work for
the Company, is or prior to and after January 1, 2000 will be Year 2000
Compliant, and has provided copies of all such certification received to date to
Parent. Based on its review and assessment, the Company has no reason to believe
any material liability or expense will result from or arise out of failure of
any of its or its Subsidiaries, computer systems, hardware, software, databases,
devices and/or equipment to be Year 2000 Compliant.

         2.20 INSURANCE. Section 2.20 of the Company Disclosure Schedule sets
forth a true and complete list of all material insurance policies and fidelity
bonds covering the assets, business, equipment, properties, operations,
employees, officers and directors of the Company and its Subsidiaries. There is
no claim by the Company or any of its Subsidiaries pending under any of such
policies or bonds as to which coverage has been questioned, denied or disputed
by the underwriters of such policies or bonds. All premiums payable under all
such policies and bonds have been paid and the Company and its Subsidiaries are
otherwise in full compliance with the terms of such policies and bonds (or other
policies and bonds providing substantially similar insurance coverage), and the
Company shall, and shall cause its Subsidiaries to, maintain in full force and
effect all such insurance during the period from the date hereof through the
Closing Date. Such policies of insurance and bonds are of the type and in
amounts customarily carried by Persons conducting businesses similar to those of
the Company and its Subsidiaries and reasonable in light of the assets of the
Company and its Subsidiaries. As of the date hereof, the Company has not
received notice of any, and to Company's Knowledge there is no threatened,
termination of or material premium increase with respect to any of such policies
or bonds.

         2.21 BROKERS. No broker, financial advisor, finder or investment banker
or other Person (other than Petkevich & Partners, L.L.C.) is entitled to any
broker's, financial advisor's,

                                       28
<PAGE>   34


finder's or other fee or commission in connection with the transactions
contemplated by this Agreement based upon arrangements made by or on behalf of
the Company. The Company has heretofore furnished to Parent a complete and
correct copy of all agreements set forth in Section 2.21 of the Company
Disclosure Schedule between the Company and financial advisor pursuant to which
such firm would be entitled to any payment relating to the transactions
contemplated hereunder.

         2.22 CERTAIN BUSINESS PRACTICES. As of the date hereof, neither the
Company nor any of its Subsidiaries nor any director, officer, employee or agent
of the Company or any of its Subsidiaries has (i) used any funds for unlawful
contributions, gifts, entertainment or other unlawful payments relating to
political activity, (ii) made any unlawful payment to any foreign or domestic
government official or employee or to any foreign or domestic political party or
campaign or violated any provision of the Foreign Corrupt Practices Act of 1977,
as amended, (iii) consummated any transaction, made any payment, entered into
any agreement or arrangement or taken any other action in violation of Section
1128B(b) of the Social Security Act, as amended, or (iv) made any other unlawful
payment.

         2.23 INTERESTED PARTY TRANSACTIONS. Except as disclosed in the Company
SEC Reports or except as set forth in Section 2.23 of the Company Disclosure
Schedule, neither the Company nor any of its Subsidiaries is indebted to any
director, officer, employee or agent of the Company or any of its Subsidiaries
(except for amounts due as normal salaries and bonuses and in reimbursement of
ordinary expenses), and no such Person is indebted to the Company or any of its
Subsidiaries, and there have been no other transactions of the type required to
be disclosed pursuant to Items 402 and 404 of Regulation S-K under the
Securities Act and the Exchange Act.

         2.24 OPINION OF FINANCIAL ADVISOR. The Company has received the written
opinion of its financial advisor, Petkevich & Partners, L.L.C., to the effect
that, in its opinion, as of the date hereof, the aggregate consideration to be
received in the Merger is fair to the holders of the capital stock of the
Company from a financial point of view, and the Company has provided copies of
such opinion to Parent.

         2.25     NO SUBSIDIARIES.  The Company has no Subsidiaries.

         2.26 DISCLOSURE. The representations and warranties and statements of
the Company contained in this Agreement (including the Company Disclosure
Schedule) do not contain, and will not contain at the Closing Date, any untrue
statement of a material fact, and do not omit, and will not omit at the Closing
Date, to state any material fact necessary to make such representations,
warranties and statements, in light of the circumstances under which they are
made, not misleading. There is no fact known to the Company that has not been
disclosed to the Parent in this Agreement (including in the Company SEC Filings
or the Company Disclosure Schedule) that is reasonably likely to have a Material
Adverse Effect on the Company.

         2.27 HSR FILING. No filing under the HSR Act is required in connection
with the Merger, because the Company does not have annual net sales or total
assets greater than or equal to $10,000,000.

                                       29
<PAGE>   35


                                   ARTICLE III

             REPRESENTATIONS AND WARRANTIES OF PARENT AND MERGER SUB

         Parent and Merger Sub hereby, jointly and severally, represent and
warrant to the Company that:

         3.1 ORGANIZATION AND QUALIFICATION. Each of Parent and Merger Sub is a
corporation duly organized, validly existing and in good standing under the laws
of its respective jurisdiction of incorporation or organization and Parent has
all the requisite corporate power and authority, and is in possession of all
franchises, grants, authorizations, licenses, permits, easements, consents,
certificates, approvals and Orders ("Parent Approvals") necessary to own, lease
and operate its properties and to carry on its business as it is now being
conducted, except where the failure to be so qualified, existing and in good
standing or to have such power, authority and Parent Approvals would not,
individually or in the aggregate, have a Material Adverse Effect. Each of Parent
and Merger Sub is duly qualified or licensed as a foreign corporation to do
business, and is in good standing, in each jurisdiction where the character of
the properties owned, leased or operated by it or the nature of its activities
makes such qualification or licensing necessary, except for such failures to be
so duly qualified or licensed and in good standing that would not, either
individually or in the aggregate, have a Material Adverse Effect. Merger Sub is
a newly-formed single purpose entity which has been formed solely for the
purposes of the Merger, has carried on no business to date and will not carry on
any business or engage in any activities other than those necessary to the
Merger.

         3.2      CAPITALIZATION.

                  (a) As of the date hereof, the authorized capital stock of
Parent consists of (i) 50,000,000 shares of Parent Common Stock of which
16,881,800 shares of Parent Common Stock were issued and outstanding as of July
28, 1999, and 2,178,517 shares of Parent Common Stock as of August 1, 1999, were
reserved for future issuance pursuant to outstanding employee stock options or
other outstanding stock options and (ii) 5,000,000 shares of preferred stock,
par value $.01 per share, of which 500,000 shares have been designated as Series
A-1 Junior Participating Preferred Stock and reserved for issuance under the
Parent's Rights Agreement, of which none are issued or outstanding. Parent has
no warrants outstanding as of the date of this Agreement. All of the outstanding
shares of Parent Common Stock are, and all shares to be issued as part of the
Common Merger Consideration and the Preferred Merger Consideration will be, when
issued in accordance with the terms hereof, duly authorized, validly issued,
fully paid and nonassessable and not subject to preemptive rights.

                  (b) As of the date hereof, the authorized capital stock of
Merger Sub consists of 3,000 shares of Merger Sub Common Stock, of which 100
shares of Merger Sub Common Stock are outstanding. All of the outstanding shares
of Merger Sub Common Stock are owned by Parent.

                                       30
<PAGE>   36


         3.3 AUTHORIZATION OF AGREEMENT. Each of Parent and Merger Sub has all
requisite corporate power and authority to execute and deliver this Agreement
and each instrument required hereby to be executed and delivered by it at the
Closing, to perform its obligations hereunder and thereunder and to consummate
the transactions contemplated hereby and thereby. The execution and delivery by
each of Parent and Merger Sub of this Agreement and each instrument required
hereby to be executed and delivered by it at the Closing, the performance of
obligations hereunder and thereunder and the consummation of the transactions
contemplated hereby and thereby have been duly and validly authorized by the
Board of Directors of each of Parent and Merger Sub and by Parent as the sole
stockholder of Merger Sub and except for filing of the Certificate of Merger, no
other corporate proceedings on the part of Parent or Merger Sub are necessary to
authorize this Agreement or to consummate the transactions contemplated hereby.
This Agreement has been duly executed and delivered by each of Parent and Merger
Sub and, assuming due authorization, execution and delivery hereof by the
Company, constitutes a legal, valid and binding obligation of each of Parent and
Merger Sub, enforceable against each of Parent and Merger Sub in accordance with
its terms, in each case except to the extent that the enforcement hereof may be
limited by (A) bankruptcy, insolvency, reorganization, moratorium or other
similar law now or hereafter in effect relating to creditors' rights generally
and (B) general principles of equity (regardless of whether enforceability is
considered in a proceeding in equity or at law). No other corporate proceedings
are required by Parent other than the approval of the Board of Directors of
Parent and Merger Sub.

         3.4 APPROVALS. The execution and delivery by Parent and Merger Sub of
this Agreement or any instrument required by this Agreement to be executed and
delivered by Parent or Merger Sub at the Closing do not, and the performance by
each of Parent and Merger Sub of its respective obligations under this Agreement
or any instrument required by this Agreement to be executed and delivered by
Parent or Merger Sub at the Closing shall not, require Parent or Merger Sub to
obtain any consent, approval, authorization, license, waiver, qualification,
Order or permit of, observe any waiting period imposed by, or require Parent or
Merger Sub to make any filing with or notification to, any Court or Governmental
Authority, except for (A) compliance with applicable requirements, if any, of
the Securities Act, the Exchange Act or Blue Sky Laws, (B) the filing of
appropriate Merger or other documents as required by Delaware Law, (C) the
filing of appropriate Merger or other documents as required by the NASDAQ or (D)
where the failure to obtain such consents, approvals, authorizations, licenses,
waivers, qualifications, Orders or permits, or to make such filings or
notifications, would not have, in the aggregate, a Material Adverse Effect.

         3.5 NO VIOLATION. Assuming effectuation of all filings, notifications,
and registrations with, termination or expiration of any applicable waiting
periods imposed by and receipt of all permits or Orders of Courts and/or
Governmental Authorities set forth in Section 3.4(A), (B) or (C) above, the
execution and delivery by Parent and Merger Sub of this Agreement or any
instrument required by this Agreement to be executed and delivered by Parent or
Merger Sub at the Closing do not, and the performance of this Agreement by each
of Parent or Merger Sub of its respective obligations under this Agreement or
any instrument required by this Agreement to be executed and delivered by Parent
or Merger Sub at the Closing will not, (i) conflict with or violate the
Certificate of Incorporation or By-laws of Parent or the Certificate of

                                       31
<PAGE>   37


Incorporation or By-laws of Merger Sub, (ii) conflict with or violate any Law,
Order or Regulation in each case applicable to Parent or Merger Sub or by which
either of its respective properties is bound or affected, or (iii) result in any
breach or violation of or constitute a default (or an event that with notice or
lapse of time or both would become a default) under any note, bond, mortgage,
indenture, contract, agreement, lease, license, permit, franchise or other
instrument or obligation to which the Parent or Merger Sub is a party or by
which Parent or Merger Sub or any of their respective properties is bound or
affected, except in the case of clause (ii) or (iii) above, for any such
conflicts, breaches, violations, defaults or other occurrences that would not
(a) individually, or in the aggregate, have a Material Adverse Effect or (b)
prevent or materially impair or delay the consummation of the Merger.

         3.6      REPORTS.

                  (a) As of the date of this Agreement, Parent has timely filed
all reports and schedules required to be filed with the SEC (collectively, the
"Parent SEC Reports") pursuant to the Exchange Act and the SEC Regulations
promulgated thereunder. The Parent SEC Reports were prepared in accordance, and
complied as of their respective dates in all material respects, with the
requirements of the Exchange Act and the SEC Regulations promulgated thereunder
and did not as of their respective dates (or if amended by a filing prior to the
date hereof, then as of the date of such amendment) contain any untrue statement
of a material fact or omit to state a material fact required to be stated
therein or necessary in order to make the statements therein, in the light of
the circumstances under which they were made, not misleading, except to the
extent superseded by a Parent SEC Report filed subsequently and prior to the
date hereof.

                  (b) Each of the consolidated financial statements (including,
in each case, any related notes thereto) contained in Parent SEC Reports (i)
complied in all material respects with applicable accounting requirements and
the published SEC Regulations with respect thereto, (ii) were prepared in
accordance with GAAP (except in the case of interim balance sheets, as permitted
by Regulation S-X promulgated by the SEC) applied on a consistent basis
throughout the periods involved (except as may be expressly described in the
notes thereto) and (iii) fairly presents the consolidated financial position of
the Parent as at the respective dates thereof and the consolidated results of
its operations and cash flows for the periods indicated, except that the
unaudited interim financial statements included in the Company's Form 10-Q
reports were or are subject to normal year-end adjustments that have not been
and are not expected to be material in amount to Parent.

         3.7 ABSENCE OF CERTAIN CHANGES OR EVENTS. Since December 31, 1998,
Parent has conducted its business only in the ordinary and usual course and in a
manner consistent with past practice and, since such date, there has not
occurred any event, development or change which, individually or in the
aggregate, has resulted in or is reasonably likely to result in a Material
Adverse Effect.

         3.8 REGISTRATION STATEMENT; PROXY STATEMENT/PROSPECTUS. The information
supplied by Parent for inclusion in the Registration Statement shall not, at the
time it is filed with the SEC and at the time the Registration Statement
(including any amendments or supplements

                                       32
<PAGE>   38


thereto) is declared effective by the SEC, contain any untrue statement of a
material fact or omit to state any material fact required to be stated therein
or necessary in order to make the statements therein, in light of the
circumstances under which they were made, not misleading. The information
supplied by Parent for inclusion in the Proxy Statement shall not, on the date
the Proxy Statement is first mailed to the stockholders of the Company, at the
time of the Company Stockholders' Meeting and at the Effective Time, contain any
statement which, at such time, is false or misleading with respect to any
material fact, or omit to state any material fact necessary in order to make the
statements made therein, in light of the circumstances under which they are
made, not false or misleading or omit to state any material fact necessary to
correct any statement in any earlier communication with respect to the
solicitation of proxies for the Company Stockholders' Meeting which has become
materially false or misleading. If at any time prior to the Effective Time any
event relating to Parent or Merger Sub or any of their respective affiliates,
officers or directors is discovered by Parent which should be set forth in an
amendment to the Registration Statement or an amendment or supplement to the
Proxy Statement, Parent shall promptly inform the Company. The Registration
Statement will comply as to form in all material respects with the requirements
provisions of the Securities Act and the SEC Regulations promulgated thereunder.
Notwithstanding the foregoing, Parent makes no representation, warranty or
covenant with respect to any information supplied by the Company which is
contained in any of the foregoing documents.

         3.9 ABSENCE OF LITIGATION. Except as set forth in the Parent SEC
Reports, there is no Litigation pending, or to the Parent's Knowledge,
threatened against the Parent or Merger Sub, that would be or have a Material
Adverse Effect on the Parent. Neither the Parent nor the Merger Sub is subject
to any outstanding Claim or Order other than as set forth in the Parent SEC
Reports, which, individually or in the aggregate, has, or in the future might
have, a Material Adverse Effect on the business or results of operations of the
Parent.

         3.10     COMPLIANCE WITH LAWS.

                  (a) Each of Parent and Merger Sub has all Permits necessary to
conduct the business of the Parent and Merger Sub as currently conducted,
respectively; such Permits are in full force and effect; and all applications
for renewal necessary to maintain any Permit in effect have been filed, except,
in each case, where the failure to own, maintain or renew such Permits would
not, individually or in the aggregate, have a Material Adverse Effect on Parent
or Merger Sub. No proceeding is pending, or to the best Knowledge of the Parent,
threatened to revoke or limit any Permit.

                  (b) Neither Parent nor Merger Sub is in violation of any
applicable law, ordinance or regulation or any order, judgment, injunction,
decree or other requirement of any court, arbitrator or governmental or
regulatory body, except for violations that would not, in the aggregate, have a
Material Adverse Effect on Parent or Merger Sub.

                  (c) To the best Knowledge of Parent, there is no investigation
or review pending by any governmental body or authority with respect to Parent.

                                       33
<PAGE>   39


         3.11 TAXES. Each of the Parent and Merger Sub has filed all Tax Returns
required to be filed by it and has paid all Taxes and other charges shown as due
on such Tax Returns. All positions taken in such Tax Returns that could give
rise to a substantial understatement penalty within the meaning of Section 6662
of the Code have been disclosed therein. Neither the Parent nor Merger Sub is
delinquent in any material Tax assessment or other governmental charge
(including without limitation applicable withholding taxes). Any provision for
Taxes reflected in the Parent financial statements is adequate for payment of
any and all Tax liabilities for periods ending on or before December 31, 1998
and there are no Tax Liens on any assets of the Parent or Merger Sub for periods
ending on or before March 31, 1999.


         3.12 YEAR 2000 COMPLIANCE. Parent has undertaken the review and
assessment of its business and operations that could be adversely affected by
its failure to be Year 2000 Compliant. Based on its review and assessment,
Parent has no reason to believe any material liability or expense will result
from or arise out of failure of any of its computer systems, hardware, software,
databases, devices and/or equipment to be Year 2000 Compliant.

         3.13 PARENT INTELLECTUAL PROPERTY RIGHTS. To the Parent's Knowledge, no
third party is misappropriating, infringing, diluting, or violating any of the
Parent Intellectual Property Rights and no such claims have been brought against
any third party by the Parent, and the Parent has not knowingly misappropriated
the trade secrets of any third party. For purposes of this Section 3.13, "Parent
Intellectual Property Rights" shall mean all of the Parent's United States and
foreign (i) patents and patent applications, (ii) registered and unregistered
trademarks and trademark applications (including material Internet domain name
registrations), (iii) service marks and service mark applications, (iv) trade
names, (v) copyright registrations, and copyright applications, and (vi)
licenses presently used by Parent and/or its Subsidiaries, excluding all Parent
Intellectual Property Rights subject to a shrinkwrap or similar mass marketing
license.

                                   ARTICLE IV

                     CONDUCT OF BUSINESS PENDING THE MERGER

         4.1 CONDUCT OF BUSINESS BY THE COMPANY PENDING THE MERGER. The Company
covenants and agrees that, between the date hereof and the Effective Time,
except as expressly required or permitted by this Agreement or unless Parent
shall otherwise agree in writing, the Company shall conduct and shall cause the
businesses of each of its Subsidiaries to be conducted only in, and the Company
and its Subsidiaries shall not take any action except in, the ordinary course of
business and in a manner consistent with past practice. The Company shall use
its best efforts to preserve intact the business organization and assets of the
Company and each of its Subsidiaries, and to operate, and cause each of its
Subsidiaries to operate, according to plans and budgets provided to Parent, to
keep available the services of the present officers, employees and consultants
of the Company and each of its Subsidiaries, to maintain in effect Material
Agreements and to preserve the present relationships of the Company and each of
its Subsidiaries with advertisers, sponsors, customers, licensees, suppliers and
other Persons with which the Company or any of its Subsidiaries has business
relations. By way of amplification and not

                                       34
<PAGE>   40


limitation, except as expressly permitted by this Agreement, neither the Company
nor any of its Subsidiaries shall, between the date hereof and the Effective
Time, directly or indirectly do, or propose to do, any of the following without
the prior written consent of Parent:

                  (a) amend or otherwise change the Certificate of Incorporation
or By-laws or equivalent organizational document of the Company or any of its
Subsidiaries or alter through merger, liquidation, reorganization, restructuring
or in any other fashion the corporate structure or ownership of the Company or
any of its Subsidiaries;

                  (b) issue, sell, transfer, pledge, dispose of or encumber, or
authorize the issuance, sale, transfer, pledge, disposition or encumbrance of,
any shares of capital stock of any class, or any options, warrants, convertible
securities or other rights of any kind to acquire any shares of capital stock,
or any other ownership interest of the Company, any of its Subsidiaries or
Affiliates (except for the issuance of Company Common Shares issuable pursuant
to employee stock options granted prior to the date hereof under the 1994 Plan,
1995 Plan, or outside of any plan, which options are outstanding on the date
hereof or pursuant to Company Warrants outstanding on the date hereof); or sell,
transfer, pledge, dispose of or encumber, or authorize the sale, transfer,
pledge, disposition or encumbrance of any assets of the Company or any of its
Subsidiaries (except for sales of assets in the ordinary course of business and
in a manner consistent with past practice) or redeem, purchase or otherwise
acquire, directly or indirectly, any of the capital stock of the Company or
interest in or securities of any Subsidiary;

                  (c) declare, set aside or pay any dividend or other
distribution (whether in cash, stock or property or any combination thereof) in
respect of any of its capital stock (except that a wholly owned Subsidiary of
the Company may declare and pay a dividend to its parent); split, combine or
reclassify any of its capital stock or issue or authorize or propose the
issuance of any other securities in respect of, in lieu of or in substitution
for shares of its capital stock or amend the terms of, repurchase, redeem or
otherwise acquire, or permit any Subsidiary to repurchase, redeem or otherwise
acquire, any of its securities or any securities of its Subsidiaries, or propose
to do any of the foregoing;

                  (d) sell, transfer, lease, license, sublicense, mortgage,
pledge, dispose of, encumber, grant or otherwise dispose of any Intellectual
Property Rights, or amend or modify in any material way any existing agreements
with respect to any Intellectual Property Rights, except as set forth in Section
4.1(l) of the Company Disclosure Schedule.

                  (e) acquire (by merger, consolidation, acquisition of stock or
assets or otherwise) any corporation, limited liability company, partnership,
joint venture or other business organization or division thereof; incur any
indebtedness for borrowed money or issue any debt securities (other than a debt
financing of up to $1,000,000 (the "Bridge Loan"), which Bridge Loan shall not
include in its terms any form of equity to be issued to the lender(s) of the
Bridge Loan) or assume, guarantee (other than guarantees of bank debt of the
Company's Subsidiaries entered into in the ordinary course of business) or
endorse or otherwise as an accommodation become responsible for, the obligations
of any Person, or make any loans, advances or enter into any financial
commitments, except in the ordinary course of business consistent with past

                                       35
<PAGE>   41


practice and as otherwise permitted under any loan or credit agreement to which
the Company is a party; authorize any capital expenditures which are, in the
aggregate, in excess of $100,000 for the Company and its Subsidiaries taken as a
whole; or enter into or amend in any material respect any contract, agreement,
commitment or arrangement with respect to any of the matters set forth in this
Section 4.1(e);

                  (f) hire or terminate any employee or consultant, except in
the ordinary course of business consistent with past practice; increase the
compensation (including, without limitation, bonus) payable or to become payable
to its officers or employees, except for increases in salary or wages of
employees of the Company or its Subsidiaries who are not officers of the Company
in the ordinary course of business consistent with past practices, or grant any
severance or termination pay or stock options to, or enter into any employment
or severance agreement with any director, officer or other employee of the
Company or any of its Subsidiaries, or establish, adopt, enter into or amend any
collective bargaining, bonus, profit sharing, thrift, compensation, stock
option, restricted stock, pension, retirement, deferred compensation,
employment, termination, severance or other plan, agreement, trust, fund, policy
or arrangement for the benefit of any current or former directors, officers or
employees;

                  (g) change, any accounting policies or procedures (including
procedures with respect to reserves, revenue recognition, payments of accounts
payable and collection of accounts receivable) unless required by statutory
accounting principles or GAAP;

                  (h) create, incur, suffer to exist or assume any Lien on any
of their material assets other than Liens outstanding on the date hereof;

                  (i) except as set forth in Section 4.1(l) of the Company
Disclosure Schedule, other than in the ordinary course of business consistent
with past practice, (A) enter into any material agreement, (B) modify, amend or
transfer in any material respect or terminate any material agreement to which
the Company or any of its Subsidiaries is a party or waive, release or assign
any material rights or claims thereto or thereunder or (C) enter into or extend
any lease with respect to real property with any third party;

                  (j) make any Tax election or settle or compromise any federal,
state, local or foreign income tax liability or agree to an extension of a
statute of limitations;

                  (k) settle any material Litigation or waive, assign or release
any material rights or claims except, in the case of Litigation, any Litigation
which settlement would not (A) impose either material restrictions on the
conduct of the business of the Company or any of its Subsidiaries or (B) for any
individual Litigation item settled, exceed $50,000 in cost or value to the
Company or any of its Subsidiaries. The Company and its Subsidiaries shall not
pay, discharge or satisfy any liabilities or obligations (absolute, accrued,
asserted or unasserted, contingent or otherwise), except in the ordinary course
of business consistent with past practice in an amount or value not exceeding
$100,000 in any instance or series of related instances or $100,000 in the
aggregate or in accordance with their terms as in effect as of the date hereof;

                                       36
<PAGE>   42


                  (l) engage in any transaction, or enter into any agreement,
arrangement, or understanding with, directly or indirectly, any related party,
other than those contemplated pursuant to the terms of this Agreement and those
existing as of the date hereof which are listed in Section 4.1(l) of the Company
Disclosure Schedule;

                  (m) fail to renew or maintain in full force and effect all
insurance policies, as the case may be, currently in effect or fail to pay any
insurance premiums thereon; and

                  (n) authorize, recommend, propose or announce an intention to
do any of the foregoing, or agree or enter into any agreement, contract
commitment or arrangement to do any of the foregoing.

         4.2      SOLICITATION OF OTHER PROPOSALS.

                  (a) From the date hereof until the earlier of the Effective
Time or the termination of this Agreement in accordance with its terms, the
Company shall not, nor shall it permit any of its Subsidiaries or any of its or
their respective officers, directors, employees, representatives or agents
(collectively, the "Company Representatives") to, and the Company shall use its
best efforts to cause its stockholder Affiliates not to, directly or indirectly,
(i) solicit, facilitate, initiate or encourage, or take any action to solicit,
facilitate, initiate or encourage, any inquiries or the making of any proposal
or offer that constitutes an Acquisition Proposal or (ii) participate or engage
in discussions or negotiations with, or provide any information to, any Person
concerning an Acquisition Proposal or which might reasonably be expected to
result in an Acquisition Proposal.

                  For purposes of this Agreement, the term "Acquisition
Proposal" shall mean any inquiry, proposal or offer from any person (other than
Parent, Merger Sub or any of their Affiliates) relating to:

                           (1) any merger, consolidation, recapitalization,
         liquidation or other direct or indirect business combination, involving
         the Company or any Subsidiary or the issuance or acquisition of shares
         of capital stock or other equity securities of the Company or any
         Subsidiary representing 10% or more of the outstanding capital stock of
         the Company or such Subsidiary or any tender or exchange offer that if
         consummated would result in any Person, together with all Affiliates
         thereof, beneficially owning shares of capital stock or other equity
         securities of the Company or any Subsidiary representing 10% or more of
         the outstanding capital stock of the Company or such Subsidiary, or

                           (2) the sale, lease, exchange, license (whether
         exclusive or not), or any other disposition of any significant portion
         of a material Intellectual Property Right (other than as permitted
         pursuant to Section 4.1(d) hereof), or any significant portion of the
         business or other assets of the Company or any Subsidiary, or any other
         transaction, the consummation of which could reasonably be expected to
         impede, interfere with, prevent or materially delay the consummation of
         the transactions contemplated hereby or which would reasonably be
         expected to diminish significantly the benefits to Parent or its
         Affiliates of the transactions contemplated hereby.

                                       37
<PAGE>   43


The Company shall immediately cease and cause to be terminated and shall cause
all Company Representatives (and shall use its best efforts to cause its
non-officer and non-director Affiliates) to terminate all existing discussions
or negotiations with any Persons conducted heretofore with respect to, or that
could reasonably be expected to lead to, an Acquisition Proposal. The Company
shall promptly notify all Company Representatives and non-officer and
non-director Affiliates of its obligations under this Section 4.2.

                  (b) Neither the Board of Directors of the Company nor any
committee thereof shall:

                           (1) approve or recommend, or propose to approve or
         recommend, any Acquisition Proposal other than the Merger,

                           (2) withdraw or modify or propose to withdraw or
         modify in a manner adverse to Parent or Merger Sub its approval or
         recommendation of the Merger, this Agreement or the transactions
         contemplated hereby,

                           (3) upon a request by Parent to reaffirm its approval
         or recommendation of this Agreement or the Merger, fail to do so within
         two (2) Business Days after such request is made,

                           (4) enter, or cause the Company or any Subsidiary to
         enter, into any letter of intent, agreement in principle, acquisition
         agreement or other similar agreement related to any Acquisition
         Proposal, or

                           (5) resolve or announce its intention to do any of
         the foregoing.

The immediately preceding sentence notwithstanding, in the event that prior to
the Company Stockholders' Meeting the Board of Directors of the Company receives
a Superior Proposal, the Board of Directors of the Company may:

                                    (i) approve or recommend, or propose to
                  approve or recommend, such Superior Proposal,

                                    (ii) withdraw or modify, or propose to
                  withdraw or modify, in a manner adverse to Parent or Merger
                  Sub its recommendation of the Merger, this Agreement or the
                  transactions contemplated hereby,

                                    (iii) fail to reaffirm its recommendation of
                  this Agreement or the Merger after a request by Parent to do
                  so, or

                                    (iv) resolve or announce its intention to do
                  any of the actions set forth in the preceding clauses (i)
                  through (iii),

if (1) such Board of Directors determines in good faith, after consultation with
its outside counsel that taking such action is required to satisfy the fiduciary
duties of such directors and (2) the

                                       38
<PAGE>   44


Company furnishes Parent two Business Days' prior written notice of the taking
of such action (which notice shall include a description of the material terms
and conditions of the Superior Proposal).

For purposes of the Agreement, the term "Superior Proposal" means any bona fide
Acquisition Proposal to (A) effect a merger, consolidation or sale of all or
substantially all of the assets or capital stock of the Company or (B) license
or otherwise dispose of any material Intellectual Property Right (other than as
permitted pursuant to Section 4.1(d)) which is on terms which the Board of
Directors of the Company determines by a majority vote of its directors in their
good faith judgment (based on the written opinion, with only customary
qualifications, of a financial advisor reasonably acceptable to the Parent that
the consideration provided in such Acquisition Proposal likely exceeds the value
of the consideration provided for in the Merger), after taking into account all
relevant factors, including any conditions to such Acquisition Proposal, the
timing of the closing thereof, the risk of nonconsummation, the ability of the
person making the Acquisition Proposal to finance the transaction contemplated
thereby and any required governmental or other consents, filings and approvals,
to be more favorable to the stockholders of the Company than the Merger (or any
revised proposal made by Parent).

                  (c) In addition to the other obligations of the Company set
forth in this Section 4.2, the Company shall immediately advise Parent orally
and in writing of any request for information with respect to any Acquisition
Proposal, or any inquiry with respect to or which could result in an Acquisition
Proposal, the material terms and conditions of such request, Acquisition
Proposal or inquiry. The Company shall inform Parent on a prompt and current
basis of the status and content of any discussions regarding any Acquisition
Proposal with a third party and as promptly as practicable of any change in the
price, structure or form of the consideration or material terms of and
conditions regarding any Acquisition Proposal or of any other developments or
circumstances which could reasonably be expected to culminate in the taking of
any of the actions referred to in Section 4.2(b). Nothing contained in this
Section 4.2(c) shall prevent the Board of Directors of the Company from
complying with Rule 14d-9 and Rule 14e-2 promulgated under the Exchange Act.


                                    ARTICLE V

                              ADDITIONAL AGREEMENTS

         5.1      PROXY STATEMENT/PROSPECTUS; REGISTRATION STATEMENT.

                  (a) As promptly as practicable following the date of this
Agreement, Parent shall prepare and file with the SEC the Registration Statement
on Form S-4, in which the Proxy Statement shall be included as a prospectus, and
shall use reasonable efforts to have the Registration Statement declared
effective by the SEC as promptly as practicable. Parent shall obtain and furnish
the information required to be included in the Registration Statement and, after
consultation with the Company respond promptly to any comments made by the SEC
with respect to the Registration Statement (which comments shall promptly be
furnished to the

                                       39
<PAGE>   45


Company) and cause the prospectus included therein, including any amendment or
supplement thereto, to be mailed to the stockholders of the Company at the
earliest practicable date after the Registration Statement is declared effective
by the SEC, provided that no amendment or supplement to the Registration
Statement will be made by Parent without consultation with the Company and its
counsel. Parent shall also take any action required to be taken under Blue Sky
or other securities Laws in connection with the issuance of Parent Common Stock
in the Merger.

                  (b) The Company shall (i) as promptly as practicable following
the date hereof prepare a preliminary proxy or information statement relating to
the Merger and this Agreement, (ii) obtain and furnish the information required
to be included by the SEC in the Proxy Statement, (iii) cause the Proxy
Statement and the prospectus to be included in the Registration Statement,
including any amendment or supplement thereto, to be mailed to its stockholders
at the earliest practicable date after the Registration Statement is declared
effective by the SEC, and (iv) use all reasonable efforts to obtain the
necessary approval of the Merger and this Agreement by its stockholders. The
Company shall not file with or supplementally provide to the SEC or mail to its
stockholders the Proxy Statement or any amendment or supplement thereto without
Parent's prior consent. The Company shall allow Parent's full participation in
the preparation of the Proxy Statement and any amendment or supplement thereto
and shall consult with Parent and its advisors concerning any comments from the
SEC with respect thereto.

                  (c) The Proxy Statement shall include the recommendation of
the Board of Directors of the Company in favor of approval and adoption of this
Agreement and the Merger, except to the extent that the Company shall have
withdrawn or modified its recommendation of this Agreement or the Merger as
permitted by Section 4.2(b).

                  (d) Parent and the Company shall, as promptly as practicable,
make all necessary filings with respect to the Merger under the Securities Act
and the Exchange Act and the rules and Regulations thereunder and under
applicable Blue Sky or similar securities laws, rules and Regulations, and shall
use all reasonable efforts to obtain required approvals and clearances with
respect thereto.

         5.2 MEETING OF COMPANY STOCKHOLDERS. The Company shall promptly after
the date hereof take all action necessary in accordance with the provisions of
the DGCL and the Company's Certificate of Incorporation and By-laws to duly
call, give notice of and (unless Parent requests otherwise) hold the Company
Stockholders' Meeting as soon as practicable following the date upon which the
Registration Statement becomes effective and shall consult with Parent in
connection therewith. Once the Company Stockholders Meeting has been called and
noticed, the Company shall not postpone or adjourn (other than for the absence
of a quorum and then only to a future date specified by Parent) the Company
Stockholders' Meeting without the consent of Parent. The Board of Directors of
the Company shall declare that this Agreement is advisable and, subject to
Section 4.2(b), recommend that this Agreement and the transactions contemplated
hereby be approved and authorized by the stockholders of the Company and include
in the Registration Statement and Proxy Statement a copy of such
recommendations; provided, however, that the Board of Directors of the Company
shall submit this Agreement to

                                       40
<PAGE>   46


the stockholders of the Company whether or not the Board of Directors of the
Company at any time subsequent to making such recommendation takes any action
permitted by Section 4.2(b). The Company shall solicit from stockholders of the
Company proxies in favor of the Merger and shall take all other action necessary
or advisable to secure the vote or consent of stockholders required by the DGCL
to authorize the Merger; provided, however, that this provision shall not
prohibit the Board of Directors from taking any action permitted by Section
4.2(b).

         5.3      ACCESS TO INFORMATION; CONFIDENIALITY.

                  (a) Upon reasonable notice, the Company shall (and shall cause
each of its Subsidiaries to) afford to the officers, employees, accountants,
counsel and other representatives of Parent, reasonable access, during the
period prior to the Effective Time, to all its properties, books, contracts,
commitments and records and, during such period, the Company shall (and shall
cause each of its Subsidiaries to) furnish promptly to the other all information
concerning its business, properties, books, contracts, commitments, records and
personnel as such other party may reasonably request, and each party shall make
available to the other party the appropriate individuals for discussion of such
party's business, properties and personnel as the other party may reasonably
request. No investigation pursuant to this Section 5.3(a) shall affect any
representations or warranties of the parties herein or the conditions to the
obligations of the parties hereto.

                  (b) The Parent shall keep all information obtained pursuant to
Section 5.3(a) confidential in accordance with the terms of the confidentiality
agreement, dated February 11, 1999 (the "Confidentiality Agreement"), between
Parent and the Company. Anything contained in the Confidentiality Agreement to
the contrary notwithstanding, the Company and Parent hereby agree that each such
party may issue press release(s) or make other public announcements in
accordance with Section 5.9.

         5.4      ALL REASONABLE EFFORTS; FURTHER ASSURANCES.

                  (a) Upon the terms and subject to the conditions set forth in
this Agreement, each party hereto shall use all reasonable efforts to take, or
cause to be taken, all appropriate actions, and do, or cause to be done, and to
assist and cooperate with the other party or parties in doing, all things
necessary, proper or advisable to consummate and make effective, in the most
expeditious manner practicable, the Merger and the other transactions
contemplated hereby. The Company and Parent shall use all reasonable efforts to:

                           (i) obtain all licenses, permits, consents, waivers,
         approvals, authorizations, qualifications or Orders (including all
         United States and foreign governmental and regulatory rulings and
         approvals), required to be obtained by Parent or the Company or any of
         their respective Subsidiaries, and the Company and Parent shall make
         all filings (including, without limitation, all filings with United
         States and foreign governmental or regulatory agencies) under
         applicable Law required in connection with the authorization, execution
         and delivery of this Agreement by the Company and Parent and the
         consummation by them of the transactions contemplated hereby and
         thereby, including the Merger (in connection with which Parent and the
         Company will cooperate

                                       41
<PAGE>   47


         with each other in connection with the making of all such filings,
         including providing copies of all such documents to the non-filing
         party and its advisors prior to filings and, if requested, will accept
         all reasonable additions, deletions or changes suggested in connection
         therewith);

                           (ii) furnish all information required for any
         application or other filing to be made pursuant to any applicable law
         or any applicable Regulations of any Governmental Authority (including
         all information required to be included in the Proxy Statement or the
         Registration Statement) in connection with the transactions
         contemplated by this Agreement; and

                           (iii) lift, rescind or mitigate the effects of any
         injunction, restraining order or other order adversely affecting the
         ability of any party hereto to consummate the transactions contemplated
         hereby and thereby and to prevent, with respect to any threatened
         injunction, restraining order or other Order, the issuance or entry
         thereof,

provided, however, that neither Parent nor any of its Affiliates shall be under
any obligation to (x) make proposals, execute or carry out agreements or submit
to Orders providing for the sale or other disposition or holding separate
(through the establishment of a trust or otherwise) of any assets or categories
of assets material (in nature or amount) of Parent, any of its Affiliates, the
Company or the holding separate of the Company Common Shares or Company
Preferred Shares or imposing or seeking to impose any material limitation on the
ability of Parent or any of its Subsidiaries or Affiliates to conduct their
business or own such assets or to acquire, hold or exercise full rights of
ownership of the Company Common Shares or Company Preferred Shares or (y)
otherwise take any step to avoid or eliminate any impediment which may be
asserted under any Law governing competition, monopolies or restrictive trade
practices which, in the reasonable judgment of Parent, might result in a
limitation of the benefit expected to be derived by Parent as a result of the
transactions contemplated hereby or might adversely affect the Company or Parent
or any of Parent's Affiliates. Neither party hereto will take any action which
results in any of the representations or warranties made by such party pursuant
to Articles II or III, as the case may be, becoming untrue or inaccurate in any
material respect.

                  (b) Parent and the Company shall use all reasonable efforts to
satisfy or cause to be satisfied all of the conditions precedent that are set
forth in Article VI, as applicable to each of them, and to cause the
transactions contemplated by this Agreement to be consummated. Each party
hereto, at the reasonable request of another party hereto, shall execute and
deliver such other instruments and do and perform such other reasonable acts and
things as may be necessary or desirable for effecting completely the
consummation of this Agreement and the transactions contemplated hereby.

         5.5      STOCK OPTIONS AND WARRANTS.

                  (a) As soon as practicable after the execution of this
Agreement, the Company shall, pursuant to the Company's 1994 Plan, (i) notify
each holder of an outstanding option issued pursuant to the 1994 Plan of the
proposed Merger, (ii) provide for the accelerated vesting

                                       42
<PAGE>   48


of each outstanding option so that each such option shall become fully
exercisable, (iii) notify each such holder that each option shall, unless
exercised by the holder in accordance with its terms, be canceled and terminate
on the date which is fifteen (15) days from the date of such notice, and (iv)
cause the 1994 Plan to be terminated. As soon as practicable after the execution
of this Agreement, the Company shall use its commercially reasonable best
efforts to cause the exercise or termination of all other then outstanding
employee and consultant stock options and all non-employee director stock
options, including without limitation, the incentive stock options and
non-qualified stock options issued pursuant to the Company's 1995 Plan and all
stock options granted pursuant to resolutions of the Company's Board of
Directors outside of any option plan. Notwithstanding the foregoing, under no
circumstances shall the Company be required to offer any incentives or other
consideration for the termination of such options.

                  (b) As soon as practicable after the execution of this
Agreement, the Company shall use commercially reasonable best efforts to cause
the exercise or termination of all then issued and outstanding Company Warrants.
Notwithstanding the foregoing, under no circumstances shall the Company be
required to offer any incentives or other consideration for the termination of
such Company Warrants. At the Effective Time, each Company Warrant that is
outstanding and has not been terminated, exercised or otherwise converted as of
the Effective Time shall be assumed by Parent; provided that such Company
Warrants shall by their express terms reflect, or shall be amended by the
Company and the holder thereof to reflect, the different security and the number
of shares of such security covered by such agreement based on the conversion of
Company Common Shares into Parent Common Stock. All of the holders of such
Company Warrants issued and outstanding as of the date of this Agreement are
listed on Section 2.12(k) of the Company Disclosure Schedule attached hereto.
The Company shall take all actions necessary or reasonably requested by Parent
to ensure that following the Effective Time no holder of any Company Warrant
will have any right thereunder to acquire equity securities of the Company or
any of its Subsidiaries, or any right to payment in respect of the equity
securities of the Company, any of its Subsidiaries or the Surviving Corporation,
except as provided in Section 1.8(e).

                  (c) As soon as practicable after the execution of this
Agreement, the Company shall use its commercially reasonable best efforts to
cause the holders of warrants or warrant certificates issued pursuant to the
1997 Unit Purchase Agreement to (i) surrender the 1997 Warrants in exchange for
an aggregate of 158,512 Company Common Shares, and (ii) agree to terminate the
1997 Unit Purchase Agreement.

                  (d) The Company shall use its commercially best efforts to
terminate all Company Plans as of the Effective Time or as promptly as
practicable thereafter.

                  (e) With respect to any Company Options and Company Warrants,
the Company shall not permit any holder thereof to exercise such Company Option
or Company Warrant by any means other than payment of the exercise price thereof
in cash, unless the Company is contractually obligated to do so. With respect to
any such holder, the Company shall use its commercially reasonable best efforts
to encourage such holder to exercise such Company Option and/or Company Warrant
by payment in cash.

                                       43
<PAGE>   49


         5.6      REGISTRATION RIGHTS.

                  (a) As soon as practicable after the execution of this
Agreement, the Company shall use commercially reasonable best efforts to
terminate all agreements, arrangements or commitments of any character
(contingent or otherwise) pursuant to which any person is or may be entitled or
to cause the Company or any of its Subsidiaries to file a registration statement
under the Securities Act, or which otherwise relate to the registration of any
securities of the Company, except as permitted in the following sentence. The
Company shall use its commercially reasonable best efforts to ensure that
following the Effective Time no holder of any voting or non-voting capital
stock, other equity interests, or other voting securities of the Company, or
debt or other instrument convertible or exchangeable for any voting or
non-voting capital stock, other equity interests, or other voting securities of
the Company, will have any right thereunder or with respect thereto to cause the
Company or any of its Subsidiaries to file a registration statement under the
Securities Act, or which otherwise relate to the registration of any securities
of the Company.

                  (b) Parent shall, as soon as practicable after the Closing,
but not later than sixty (60) days following the Effective Time, prepare and
file with the SEC a registration statement on Form S-8 (or any successor form
thereto) (or, if possible, amend an effective Form S-8 by filing a
post-effective amendment thereto) with respect to the shares of Parent Common
Stock which are to be issuable upon the exercise of the Assumed Options (the
"S-8") and shall use its best efforts to have the S-8 declared effective as soon
as practicable and kept effective as long as any Assumed Options are
outstanding. In addition, Parent shall, as soon as practicable after the
Closing, but not later than sixty (60) days following the Effective Time,
prepare and file with the SEC a registration statement on Form S-3 (or any
successor form thereto) to register the resale of the shares of Parent Common
Stock underlying the Company Warrants (the "S-3") and shall use its best efforts
to have the S-3 declared effective within 180 days after the Effective Time and
kept effective until the earlier of (x) the exercise, expiration or termination
of all such Company Warrants or (z) two (2) years following the Effective Time.

         5.7      NOTIFICATION OF CERTAIN MATTERS.

                  (a) The Company shall give prompt notice to Parent, and Parent
shall give prompt notice to the Company, of the occurrence, or non-occurrence,
of any event the occurrence, or non-occurrence, of which results in any
representation or warranty contained in this Agreement to be untrue or
inaccurate in any material respect (or, in the case of any representation or
warranty qualified by its terms by materiality or Material Adverse Effect, then
untrue or inaccurate in any respect) and any failure of the Company, Parent or
Merger Sub, as the case may be, to comply with or satisfy in any material
respect any covenant, condition or agreement to be complied with or satisfied by
it hereunder; provided, however, that the delivery of any notice pursuant to
this Section 5.7 shall not limit or otherwise affect the remedies available
hereunder to the party receiving such notice.

                  (b) Each of the Company and Parent shall give prompt notice to
the other of (i) any notice or other communication from any Person alleging that
the consent of such Person

                                       44
<PAGE>   50


is or may be required in connection with the Merger, (ii) any notice or other
communication from any Governmental Authority in connection with the Merger,
(iii) any Litigation, relating to or involving or otherwise affecting the
Company or its Subsidiaries or the Parent that relates to the consummation of
the Merger; (iv) the occurrence of a default or event that, with notice or lapse
of time or both, will become a default under any contract which is material to
Parent or any Material Agreement of the Company; and (v) any change that is
reasonably likely to have a Material Adverse Effect on the Company or Parent or
is likely to delay or impede the ability of either Parent or the Company to
consummate the transactions contemplated by this Agreement or to fulfill their
respective obligations set forth herein.

                  (c) Each of the Company and Parent shall give (or shall cause
their respective Subsidiaries to give) any notices to third Persons, and use,
and cause their respective Subsidiaries to use, all reasonable efforts to obtain
any consents from third Persons (i) necessary, proper or advisable to consummate
the transactions contemplated by this Agreement, (ii) otherwise required under
any contracts, licenses, leases or other agreements in connection with the
consummation of the transactions contemplated hereby or (iii) required to
prevent a Material Adverse Effect on the Company or Parent from occurring. If
any party shall fail to obtain any such consent from a third Person, such party
shall use all reasonable efforts, and will take any such actions reasonably
requested by the other parties, to limit the adverse effect upon the Company and
Parent, their respective Subsidiaries, and their respective businesses
resulting, or which would result after the Effective Time, from the failure to
obtain such consent.

         5.8 LISTING ON THE NASDAQ. Parent shall use its reasonable best efforts
to cause the Parent Common Stock to be issued in the Merger to be approved for
listing on NASDAQ, subject to official notice of issuance, prior to the
Effective Time.

         5.9 PUBLIC ANNOUNCEMENTS. Parent and the Company shall consult with and
obtain the approval of the other party before issuing any press release or other
public announcement with respect to the Merger or this Agreement and shall not
issue any such press release prior to such consultation and approval, except as
may be required by applicable law or any listing agreement related to the
trading of the shares of either party on any national securities exchange or
national automated quotation system, in which case the party proposing to issue
such press release or make such public announcement shall use reasonable efforts
to consult in good faith with the other party before issuing any such press
release or making any such public announcement. Notwithstanding the foregoing,
in the event the Company's Board of Directors withdraws its recommendation of
this Agreement in compliance herewith, the Company will no longer be required to
consult with or obtain the agreement of Parent in connection with any press
release or public announcement.

         5.10 TAKEOVER LAWS. If any form of anti-takeover statute, regulation or
Certificate of Incorporation provision or contract is or shall become applicable
to the Merger or the transactions contemplated hereby, the Company and the Board
of Directors of the Company shall grant such approvals and take such actions as
are necessary under such laws and provisions so that the transactions
contemplated hereby and thereby may be consummated as promptly as practicable on
the terms contemplated hereby and thereby and otherwise act to eliminate or

                                       45
<PAGE>   51


minimize the effects of such statute, regulation, provision or contract on the
transactions contemplated hereby or thereby.

         5.11 ACCOUNTANT'S LETTERS. Upon reasonable notice from the other, the
Company and Parent shall use reasonable efforts to cause their respective
independent public accountants to deliver to Parent or the Company, as the case
may be, a letter covering such matters as are requested by Parent or the
Company, as the case may be, and as are customarily addressed in accountant's
"comfort" letters in connection with registration statements similar to Form
S-4.

         5.12     INDEMNIFICATION OF DIRECTORS AND OFFICERS.

                  (a) From and after the Effective Time, Parent shall cause the
Surviving Corporation to, and Surviving Corporation shall, fulfill and honor in
all material respects the indemnification obligations of the Company contained
in the Certificate of Incorporation or by-laws or any equivalent organizational
document of the Company as in effect immediately prior to the Effective Time.

                  (b) For a period of six years after the Effective Time, the
Parent shall cause the Surviving Corporation to, and the Surviving Corporation
shall, maintain in effect, if available, directors' and officers' liability
insurance covering those Persons who, as of immediately prior to the Effective
Time, are covered by the Company's directors' and officers' liability insurance
policy (the "Insured Parties") on terms no less favorable to the Insured Parties
than those of the Company's present directors' and officers' liability insurance
policy; provided, however, that in no event will Parent or the Surviving
Corporation be required to expend in excess of 150% of the annual premium
currently paid by the Company for such coverage (or such coverage as is
available for 150% of such annual premium).

                  (c) The provisions of this Section 5.12 are intended to be for
the benefit of, and shall be enforceable by, each Person entitled to
indemnification hereunder and the heirs and representatives of such Person.
Parent shall not permit the Surviving Corporation to merge or consolidate with
any other Person unless the Surviving Corporation ensures that the surviving or
resulting entity will assume the obligations imposed by this Section 5.12.

         5.13 COVENANTS FOR TAX-FREE STATUS. Prior to the Effective Time, each
party shall use all reasonable commercial efforts to cause the Merger to qualify
as a reorganization within the meaning of Section 368 (a) of the Code, and will
not take any action reasonably likely to cause the Merger not to so qualify.

         5.14 STOCKHOLDER AGREEMENTS. The Company shall use its reasonable best
efforts, on behalf of Parent and pursuant to the request of Parent, to cause
each stockholder designated by the Parent (a "Consenting Stockholder") to
execute and deliver to Parent a Stockholder Agreement in the form of Exhibit A
attached hereto, concurrently with the execution of this Agreement. The Company
acknowledges and agrees to be bound by and comply with the provisions of
paragraph 2 of each of the Stockholder Agreements as if a party thereto with
respect to transfers of record of ownership of shares of the Company Common
Shares and Company Preferred Shares, and agrees to notify the transfer agent for
any Company Common

                                       46
<PAGE>   52


Shares and provide such documentation and do such other things as may be
necessary to effectuate the provisions of such Stockholder Agreements.

         5.15 RELEASE AGREEMENTS. The Company shall use its best efforts, on
behalf of Parent and pursuant to the request of Parent, to cause each Person
identified in Section 5.15 of the Company Disclosure Schedule to execute and
deliver to Parent a written release and waiver satisfactory in form and
substance to Parent in its sole discretion and in substantially the form
attached hereto as Exhibit C (the "Release Agreements") prior to the Effective
Time, providing for, among other things, release of the Company, Parent and the
Surviving Corporation and their respective Affiliates from any and all claims,
known and unknown, that such Person has or may have against such Persons through
the Effective Time.

         5.16     AFFILIATE AGREEMENTS.

                  (a) Identified in Section 5.16 of the Company Disclosure
Schedule is a list of those persons who are, in the Company's reasonable
judgment, "affiliates" of the Company, within the meaning of Rule 145
promulgated under the Securities Act ("Rule 145"). The Company shall provide
such information and documents as Parent shall reasonably request for purposes
of reviewing such list and shall notify Parent in writing regarding any change
in the identity of its affiliates prior to the Closing Date. The Company shall
use its best efforts to deliver or cause to be delivered to Parent by September
15, 1999 (and in any case prior to the Effective Time) from the Company's
affiliates, an executed Affiliate Agreement, in substantially the form attached
hereto as Exhibit D, by which each affiliate of the Company agrees to comply
with the applicable requirements of Rule 145 and other applicable securities
laws. Parent shall be entitled to place appropriate legends on the certificates
evidencing any Parent Common Stock to be received by such affiliates of the
Company pursuant to the terms of this Agreement, and to issue appropriate stop
transfer instructions to the transfer agent for the Parent Common Stock,
consistent with the terms of the Affiliate Agreements (provided that such
legends or stop transfer instructions shall be promptly removed, after the
required restricted period).

         (b) Parent shall, at all times during the two (2) year period beginning
on the Closing Date, whether or not it is subject to the reporting requirements
of Section 13 or Section 15(d) of the Exchange Act, comply with the current
public information requirements of Rule 144(c)(1) promulgated under the
Securities Act.

                                       47
<PAGE>   53


         5.17     SEC FILINGS.

                  (a) Company SEC Filings. Prior to the Effective Time, the
Company shall furnish the Parent with a copy of each periodic or current report
filed by it under the Exchange Act promptly after filing the same. All filings
made by the Company after the date hereof pursuant to the Exchange Act will be
made in timely fashion, will comply as to form in all material respects with the
applicable provisions of the Exchange Act and the rules and regulations
thereunder and will not contain any untrue statement of a material fact or omit
to state a material fact required to be stated therein or necessary to make the
statements therein, in light of the circumstances under which they are made, not
misleading.

                  (b) Parent SEC Filings. Prior to the Effective Time, the
Parent shall furnish the Company with a copy of each periodic or current report
filed by it under the Exchange Act promptly after filing the same. All filings
made by the Parent after the date hereof pursuant to the Exchange Act will be
made in timely fashion, will comply as to form in all material respects with the
applicable provisions of the Exchange Act and the rules and regulations
thereunder and will not contain any untrue statement of a material fact or omit
to state a material fact required to be stated therein or necessary to make the
statements therein, in light of the circumstances under which they are made, not
misleading.

         5.18 MAINTENANCE, PROSECUTION AND FILING OBLIGATIONS. The Company shall
pay the costs of preparation for filing, prosecution, and maintenance of all
Intellectual Property Rights as required and shall not permit the lapse of any
filings following the execution of this Agreement. The Company shall provide
copies of all filings and evidence of payments under this Section 5.18 to
Parent.

                                   ARTICLE VI

                              CONDITIONS OF MERGER

         6.1 CONDITIONS TO OBLIGATION OF EACH PARTY TO EFFECT THE MERGER. The
respective obligations of each party to effect the Merger shall be subject to
the satisfaction at or prior to the Effective Time of the following conditions,
any or all of which may be waived by the party entitled to the benefit thereof,
in whole or in part, the extent permitted by applicable Law:

                  (a) EFFECTIVENESS OF THE REGISTRATION STATEMENT. The
Registration Statement shall have been declared effective; no stop order
suspending the effectiveness of the Registration Statement shall have been
issued by the SEC and no proceedings for that purpose shall have been initiated;
and no similar proceeding in respect of the Proxy Statement shall have been
initiated or, to the Knowledge of Parent or the Company, threatened by the SEC.

                  (b) STOCKHOLDER APPROVAL. This Agreement and the Merger shall
have been authorized by the requisite vote of the stockholders of the Company in
accordance with the provisions of the DGCL and the Certificate of Incorporation
and by-laws of the Company.

                                       48
<PAGE>   54


                  (c) NASDAQ. The shares of Parent Common Stock issuable to the
stockholders of the Company pursuant to this Agreement shall have been approved
for listing on NASDAQ subject to official notice of issuance.

                  (d) REGULATORY APPROVALS. All approvals and consents of
applicable Courts and/or Governmental Authorities required to consummate the
Merger shall have been received, except for such approvals and consents, the
failure of which to have been so received, shall not have a Material Adverse
Effect.

                  (e) NO INJUNCTIONS OR RESTRAINTS; ILLEGALITY. No temporary
restraining order, preliminary or permanent injunction or other Order (whether
temporary, preliminary or permanent) issued by any court of competent
jurisdiction or other legal restraint or prohibition (an "Injunction")
preventing the consummation of the Merger shall be in effect which is
non-appealable, nor shall any proceeding brought by any administrative agency or
commission or other Governmental Authority, domestic or foreign, seeking any of
the foregoing be pending, and there shall not be any action taken, or any
statute, rule, regulation or order enacted, entered, enforced or deemed
applicable to the Merger, which makes the consummation of the Merger illegal.

                  (f) NO ORDER. No Court or Governmental Authority having
jurisdiction over the Company or Parent shall have enacted, issued, promulgated,
enforced or entered any Law, Regulation or Order (whether temporary, preliminary
or permanent) which is then in effect and which has the effect of making the
Merger illegal or otherwise prohibiting consummation of the Merger substantially
on the terms contemplated by this Agreement without an opportunity for appeal by
either party.

                  (g) TAX OPINIONS. Parent and the Company shall have received
written opinions of, respectively, Mintz, Levin, Cohn, Ferris, Glovsky and
Popeo, P.C. and Andrews & Kurth, L.L.P., in form and substance reasonably
satisfactory to them to the effect that the Merger will constitute a
reorganization within the meaning of Section 368(a) of the Code. The issuance of
each of such opinions shall be conditioned on the receipt by such tax counsel of
representation letters from each of Parent, Merger Sub, the Company and each
stockholder of the Company who or which is a signatory to the Stockholders
Agreement. The specific provisions of each such representation letter shall be
in form and substance reasonably satisfactory to such tax counsel, and each such
representation letter shall be dated on or before the date of such opinion and
shall not have been withdrawn or modified in any material respect.

         6.2 ADDITIONAL CONDITIONS TO OBLIGATIONS OF PARENT AND MERGER SUB. The
obligations of Parent and Merger Sub to effect the Merger are also subject to
the following conditions, any or all of which may be waived by Parent and Merger
Sub, in whole or in part, to the extent permitted by applicable Law:

                  (a) REPRESENTATIONS AND WARRANTIES. The representations and
warranties of the Company contained in this Agreement and the Related Agreements
shall be true and correct in all material respects on and as of the Effective
Time, except for changes contemplated by this Agreement (together with the
Company Disclosure Schedule) (except for those (x)

                                       49
<PAGE>   55


representations and warranties that are qualified by materiality or Material
Adverse Effect, in which case such representations and warranties shall be true
and correct in all respects and (y) representations and warranties which address
matters only as of a particular date (in which case such representations and
warranties qualified as to materiality or Material Adverse Effect shall be true
and correct in all respects, and those not so qualified shall be true and
correct in all material respects, on and as of such particular date), with the
same force and effect as if made on and as of the Effective Time, and Parent and
Merger Sub shall have received a certificate to such effect signed by the Chief
Executive Officer and Chief Financial Officer of the Company and of each of the
Subsidiaries.

                  (b) AGREEMENTS AND COVENANTS. The Company shall have performed
or complied in all material respects with all agreements and covenants required
by this Agreement and the Related Agreements to be performed or complied with by
it on or prior to the Effective Time. Parent and Merger Sub shall have received
a certificate to such effect signed by the Chief Executive Officer and Chief
Financial Officer of the Company.

                  (c) THIRD PARTY CONSENTS. Parent shall have received evidence,
in form and substance reasonably satisfactory to it, that those licenses,
Permits, consents, waivers, approvals, authorizations, qualifications or Orders
(including all United States and foreign governmental and regulatory rulings and
approvals) of Governmental Authorities and other third parties described in
Section 2.5(a) of the Company Disclosure Schedule (or not described in Section
2.5(a) of the Company Disclosure Schedule but required as described in Section
2.5(a) and (b) of this Agreement) have been obtained, except where failure to
have been so obtained, either individually or in the aggregate, shall not have a
Material Adverse Effect.

                  (d) RELATED AGREEMENTS. Each of the Related Agreements shall
be in full force and effect as of the Effective Time and become effective in
accordance with the respective terms thereof and the actions required to be
taken thereunder by the parties thereto immediately prior to the Effective Time
shall have been taken, and each Person who or which is required or contemplated
by the parties hereto to be a party to any Related Agreement who or which did
not theretofore enter into such Related Agreement shall execute and deliver such
Related Agreement.

                  (e) CONSULTING AGREEMENTS. Parent shall have received a copy
of the Consulting Agreement and Confidentiality Agreement between Ray Bergeron
and the Company, which Agreement is reasonably satisfactory to Parent and which
will continue in full force and effect after the Effective Time. Parent shall
have received a copy of the Consulting Agreement between Stefan Borg and the
Company, and Mr. Borg's Employment Agreement with the Company shall have been
amended to be consistent with the terms set forth on Section 2.12(i) of the
Company Disclosure Schedule.

                  (f) RELEASE AGREEMENTS. Parent shall have received Release
Agreements substantially in the form of Exhibit C executed and delivered by each
Person identified on Schedule 5.15 of the Company Disclosure Schedule.

                  (g) NO MATERIAL ADVERSE EFFECT. From and including the date
hereof, there shall not have occurred any event and no circumstance shall exist
which, alone or together with

                                       50
<PAGE>   56


any one or more other events or circumstances has had, is having or would
reasonably be expected to have a Material Adverse Effect on the Company.

                  (h) DISSENTING SHARES. The Dissenting Shares shall comprise
not more than 2% of the issued and outstanding Company Common Shares and no
Company Preferred Shares.

                  (i) MERGER CERTIFICATE. The Company shall have executed and
delivered the Merger Certificate.

                  (j) OPINION OF COUNSEL TO THE COMPANY. Parent shall have
received the opinion of Andrews & Kurth, L.L.P. dated the Closing Date,
substantially in the form of Exhibit E.

                  (k) TERMINATION OF REGISTRATION RIGHTS. The Company shall have
terminated all agreements, arrangements or commitments of any character
(contingent or otherwise) pursuant to which any person is or may be entitled, or
to cause the Company or any of its Subsidiaries to file a registration statement
under the Securities Act, or otherwise relate to the registration of any
securities of the Company, except as permitted under Section 5.6 hereof.

                  (l) TERMINATION OF LIEN. Parent shall have received evidence
satisfactory to Parent that the security interest referenced on Section 2.16 of
the Company Disclosure Schedule has been terminated or otherwise expired.

         6.3 ADDITIONAL CONDITIONS TO OBLIGATIONS OF THE COMPANY. The obligation
of the Company to effect the Merger is also subject to the following conditions,
any or all of which may be waived by Company, in whole or in part, to the extent
permitted by applicable Law:

                  (a) REPRESENTATIONS AND WARRANTIES. The representations and
warranties of Parent and Merger Sub contained in this Agreement and the Related
Agreements shall be true and correct in all material respects on and as of the
Effective Time, except for changes contemplated by this Agreement, (except for
those (x) representations and warranties that are qualified by materiality or
Material Adverse Effect, in which case such representations and warranties shall
be true and correct in all respects and (y) representations and warranties which
address matters only as of a particular date (in which case such representations
and warranties qualified as to materiality or Material Adverse Effect shall be
true and correct in all respects, and those not so qualified shall be true and
correct in all material respects, on and as of such particular date), with the
same force and effect as if made on and as of the Effective Time, and the
Company shall have received a certificate to such effect signed by the Chief
Financial Officer of Parent, with respect to Parent and the Chief Financial
Officer of Merger Sub, with respect to Merger Sub.

                  (b) AGREEMENTS AND COVENANTS. Parent and Merger Sub shall have
performed or complied in all material respects with all agreements and covenants
required by this Agreement to be performed or complied with by them on or prior
to the Effective Time, and the Company shall have received a certificate to such
effect signed by the Chief Financial Officer of

                                       51
<PAGE>   57


Parent, with respect to Parent and the Chief Financial Officer of Merger Sub,
with respect to the Merger Sub.

                  (c) MERGER CERTIFICATE. Merger Sub shall have executed and
delivered the Merger Certificate.

                  (d) OPINION OF COUNSEL TO PARENT. Company shall have received
the opinion of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. dated Closing
Date, substantially in form of Exhibit F.


                                   ARTICLE VII

                        TERMINATION, AMENDMENT AND WAIVER

         7.1 TERMINATION. This Agreement may be terminated and the Merger
contemplated hereby may be abandoned at any time prior to the Effective Time,
notwithstanding approval thereof by the stockholders of the Company:

                  (a) By mutual written consent duly authorized by the Boards of
Directors of Parent and the Company; or

                  (b) By either Parent or the Company if the Merger shall not
have been consummated on or before December 31, 1999; provided, that the right
to terminate this Agreement under this Section 7.1 shall not be available to any
party whose willful failure to fulfill any material obligation under this
Agreement has been the cause of, or resulted in, the failure of the Merger to
have been consummated on or before such date; or

                  (c) By either Parent or the Company, if a court of competent
jurisdiction or governmental, regulatory or administrative agency or commission
shall have issued an order, decree or ruling or taken any other action, in each
case which has become final and non-appealable which prohibits the Merger; or

                  (d) By either Parent or the Company, if, at the Company
Stockholders' Meeting (including any adjournment or postponement thereof), the
requisite vote of the stockholders of the Company to authorize this Agreement
shall not have been obtained; or

                  (e) By Parent, if the Board of Directors of the Company or any
committee thereof shall have (1) approved or recommended, or proposed to approve
or recommend, any Acquisition Proposal other than the Merger (2) failed to
present and recommend the authorization of this Agreement and the Merger to the
stockholders of the Company, or withdrawn or modified, or proposed to withdraw
or modify, in a manner adverse to Parent or Merger Sub, its recommendation of
the Merger, this Agreement or the transactions contemplated hereby, (3) failed
to mail the Proxy Statement to its stockholders within five (5) Business Days of
when the Proxy Statement was available for mailing or failed to include therein
such approval

                                       52
<PAGE>   58


and recommendation (including the recommendation that the stockholders of the
Company vote in favor of the Merger), (4) upon a request by Parent to reaffirm
the approval and recommendation of the Merger, failed to do so within two (2)
Business Days after such request is made, (5) entered, or caused the Company or
any Subsidiary to enter, into any letter of intent, agreement in principle,
acquisition agreement or other similar agreement related to any Acquisition
Proposal, (6) taken any action prohibited by Section 4.2, or (7) resolved by the
Board or announced its intention to do any of the foregoing; or

                  (f) By Parent, if neither Parent nor Merger Sub is in material
breach of its obligations under this Agreement, and if (i) there has been a
breach at any time by the Company of any of its representations and warranties
hereunder such that Section 6.2(a) would not be satisfied (treating such time as
if it were the Effective Time for purposes of this Section 7.1(g)) or (ii) there
has been the willful breach on the part of the Company of any of its covenants
or agreements contained in this Agreement such that Section 6.2(b) will not be
satisfied (treating such time as if it were the Effective Time for purposes of
this Section 7.1(g)), and, in both case (i) and case (ii), such breach (if
curable) has not been cured within 10 days after written notice to the Company;
or

                  (g) By the Company, if it is not in material breach of its
obligations under this Agreement, and if (i) there has been a breach at any time
by Parent or Merger Sub of any of their respective representations and
warranties hereunder such that Section 6.3(a) would not be satisfied (treating
such time as if it were the Effective Time for purposes of this Section 7.1(g)),
or (ii) there has been the willful breach on the part of Parent or Merger Sub of
any of their respective covenants or agreements contained in this Agreement such
that Section 6.3(b) would not be satisfied (treating such time as if it were the
Effective Time for purposes of this Section 7.1(g)), and, in both case (i) and
case (ii), such breach (if curable) has not been cured within 10 days after
written notice to Parent and Merger Sub; or

                  (h) By Parent, if any Consenting Stockholder publicly
announces or makes a public statement of such Consenting Stockholder's
disapproval of the Merger or otherwise encourages other stockholders of the
Company not to vote in favor of the Merger.

         7.2 EFFECT OF TERMINATION. Except as provided in this Section 7.2, in
the event of the termination of this Agreement pursuant to Section 7.1, this
Agreement (other than this Section 7.2 and Sections 5.3(b), 5.12, 7.3 and
Article VIII, which shall survive such termination) will forthwith become void,
and there will be no liability on the part of Parent, Merger Sub or the Company
or any of their respective officers or directors to the other and all rights and
obligations of any party hereto will cease, except that nothing herein will
relieve any party from liability for any breach, prior to termination of this
Agreement in accordance with its terms, of any representation, warranty,
covenant or agreement contained in this Agreement.

         7.3      FEES AND EXPENSES.

                  (a) Except as set forth in this Section 7.3, all fees and
expenses incurred in connection with this Agreement and the transactions
contemplated hereby shall be paid by the party incurring such expenses, whether
or not the Merger is consummated; provided, however,

                                       53
<PAGE>   59


that Parent and the Company shall share equally all fees and expenses, other
than attorneys' fees, incurred in relation to the printing and filing of the
Proxy Statement (including any preliminary materials related thereto), the
Registration Statement (including financial statements and exhibits) and any
amendments or supplements thereto.

                  (b) In the event that any of the following occurs:

                           (i) Parent terminates this Agreement pursuant to
         Section 7.1(e) or Section 7.1(h);

                           (ii) Parent or the Company terminates this Agreement
         pursuant to Section 7.1(d) hereof and, at the time of such termination
         or prior to the Company Stockholders' Meeting, the Company shall have
         made, or proposed, communicated or disclosed in a manner which is or
         otherwise becomes public (including being known by stockholders of the
         Company) an intention to consummate an Acquisition Proposal (whether or
         not such Acquisition Proposal or any announcement or agreement relating
         to such Acquisition Proposal shall have been rejected or shall have
         been withdrawn prior to the time of such termination or of the Company
         Stockholders' Meeting); or

                           (iii) Parent or the Company terminates this Agreement
         pursuant to Section 7.1(d) hereof and the Company shall have entered
         into a binding agreement in connection with an Acquisition Proposal or
         an Acquisition Proposal shall be consummated within twelve (12) months
         following termination of this Agreement;

         then, the Company shall pay to Parent, in the case of a termination
         described in clause (i) or (ii) above, simultaneously with such
         termination of this Agreement, a fee in cash equal to $500,000, plus
         the amount of Parent Stipulated Expenses (the "Termination Fee"), which
         Termination Fee shall be payable by wire transfer of immediately
         available funds; provided that, if within twelve (12) months of a
         termination described in clause (iii) above, the Company has entered
         into a binding agreement in connection with an Acquisition Proposal or
         an Acquisition Proposal is consummated, the Company shall pay to Parent
         a fee in cash equal to $1,000,000 (the "Topping Fee") plus the amount
         of Parent Stipulated Expenses, which Topping Fee shall be payable by
         wire transfer of immediately available funds upon consummation of the
         Acquisition Proposal and which Parent Stipulated Expenses shall be
         payable upon such termination of this Agreement. Termination by the
         Company pursuant to Section 7.1(d) under circumstances where the
         Topping Fee is payable pursuant to clause (iii) above shall not be
         effective until receipt of the Topping Fee by Parent.

                  (c) If this Agreement is terminated pursuant to Section
7.1(f), then the Company shall reimburse Parent for all Parent Stipulated
Expenses not later than two (2) Business Days after the date of such
termination.

                  (d) As used in this Agreement, the term "Parent Stipulated
Expenses" shall mean those reasonable fees and expenses actually incurred by
Parent in connection with this Agreement, the Related Agreements and the
transactions contemplated hereby and thereby,

                                       54
<PAGE>   60


including fees and expenses of counsel, investment bankers, accountants,
experts, consultants and other Representatives, including (x) Parent's efforts
to acquire the Company, (y) steps taken after the date hereof to take
operational control of the Company and (z) salaries, travel costs and expenses
incurred by Parent as a result of changes to its business plan in contemplation
of the Merger.

                  (e) Nothing in this Section 7.3 shall be deemed to be
exclusive of any other rights or remedies Parent may have hereunder or under any
Related Agreement or at law or in equity for any breach of this Agreement or any
of the Related Agreements.

         7.4 AMENDMENT. This Agreement may be amended by the parties hereto by
action taken by or on behalf of their respective Boards of Directors at any time
prior to the Effective Time; provided, however, that, after approval of the
Merger by the stockholders of the Company, no amendment may be made which would
reduce the amount or change the type of consideration into which each share of
Company Common Shares and Company Preferred Shares shall be converted upon
consummation of the Merger. This Agreement may not be amended except by an
instrument in writing signed by all of the parties hereto.

         7.5 WAIVER. At any time prior to the Effective Time, any party hereto
may extend the time for the performance of any of the obligations or other acts
required hereunder, waive any inaccuracies in the representations and warranties
contained herein or in any document delivered pursuant hereto and waive
compliance with any of the agreements or conditions contained herein. Any such
extension or waiver shall be valid if set forth in an instrument in writing
signed by the party or parties to be bound thereby.


                                  ARTICLE VIII

                               GENERAL PROVISIONS

         8.1      SURVIVAL OF REPRESENTATIONS AND WARRANTIES.

                  (a) Except as set forth in Section 8.1(b) of this Agreement,
the representations, warranties and agreements of each party hereto will remain
operative and in full force and effect regardless of any investigation made by
or on behalf of any other party hereto, any Person controlling any such party or
any of their officers, directors, representatives or agents whether prior to or
after the execution of this Agreement.

                  (b) The representations and warranties in this Agreement will
terminate at the Effective Time; provided, however, this Section 8.1(b) shall in
no way limit any covenant or agreement of the parties which by its terms
contemplates performance after the Effective Time or after the termination of
this Agreement pursuant to Article VII.

         8.2 NOTICES. All notices or other communications which are required or
permitted hereunder shall be in writing and sufficient if delivered personally
or sent by nationally-

                                       55
<PAGE>   61


recognized overnight courier or by registered or certified mail, postage
prepaid, return receipt requested, or by electronic mail, with a copy thereof to
be delivered by mail (as aforesaid) within 24 hours of such electronic mail, or
by telecopier, with confirmation as provided above addressed as follows:

                  (a)      If to Parent or Merger Sub:

                           GelTex Pharmaceuticals, Inc.
                           9 Fourth Avenue
                           Waltham, Massachusetts 02154
                           Telephone:  (781) 290-5888
                           Telecopier:  (781) 672-5822
                           Attention:  Mark Skaletsky

                           With copies to:

                           Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
                           One Financial Center
                           Boston, Massachusetts  02111
                           Telephone: (617) 542-6000
                           Telecopier: (617) 542-2241
                           Attention:  Lewis J. Geffen, Esq.

                  (b)      If to the Company:

                           SunPharm Corporation
                           The Veranda, Suite 301
                           814 Highway A-1A
                           Ponte Vedra Beach, Florida  32082
                           Telephone:  (904) 394-2800
                           Telecopier:  (904) 394-2727
                           Attention:  Stefan Borg


                           And a copy to:

                           Andrews & Kurth, L.L.P.
                           2170 Buckthorne Place, Suite 150
                           The Woodlands, Texas 77380
                           Telephone: (713) 220-4801
                           Telecopier: (713) 220-4815
                           Attention:  Jeffrey R. Harder, Esq.

or to such other address as the party to whom notice is to be given may have
furnished to the other party in writing in accordance herewith. All such notices
or communications shall be

                                       56
<PAGE>   62


deemed to be received (a) in the case of personal delivery, on the date of such
delivery, (b) in the case of nationally-recognized overnight courier, on the
next Business Day after the date when sent (c) in the case of facsimile
transmission or telecopier or electronic mail, upon confirmed receipt, and (d)
in the case of mailing, on the third Business Day following the date on which
the piece of mail containing such communication was posted.

         8.3 DISCLOSURE SCHEDULES. The Company Disclosure Schedule shall be
divided into sections corresponding to the sections and subsections of this
Agreement. Disclosure of any fact or item in any section of the Company
Disclosure Schedule shall not, should the existence of the fact or item or its
contents be relevant to any other section of the Company Disclosure Schedule, be
deemed to be disclosed with respect to such sections.

         8.4 CERTAIN DEFINITIONS. For purposes of this Agreement, the term:

                  (a) "Affiliates" means, with respect to any Person, any other
Person that directly or indirectly, through one or more intermediaries,
controls, is controlled by, or is under common control with, the first mentioned
Person; including, without limitation, any partnership or joint venture in which
the Company (either alone, or through or together with any other Subsidiary)
has, directly or indirectly, an interest of 5% or more of the issued and
outstanding capital stock of such Person;

                  (b) "Balance Sheet" means the balance sheet of the Company
contained in the Company's Form 10-KSB for the year ended December 31, 1998.

                  (c) "Beneficial Owner" or "beneficially own" with respect to a
Person's ownership of any securities means

                           (i) such Person or any of such Person's Affiliates or
         associates (as defined in Rule 12b-2 under the Exchange Act) is deemed
         to beneficially own, directly or indirectly, within the meaning of Rule
         13d-3 under the Exchange Act;

                           (ii) such Person or any of such Person's Affiliates
         or associates has

                                    (A) the right to acquire (whether such right
is exercisable immediately or only after the passage of time) pursuant to any
agreement, arrangement or understanding, or upon the exercise of conversion
rights, exchange rights, right, warrants or options, or otherwise; provided,
however, that a Person shall not be deemed the beneficial owner of, or to
beneficially own, (x) securities tendered pursuant to a tender or exchange offer
made by or on behalf of such Person or any of such Person's Affiliates or
associates until such tendered securities are accepted for purchase; and

                                    (B) the right to vote pursuant to any
agreement, arrangement or understanding; provided, however, that a Person shall
not be deemed the beneficial owner of, or to beneficially own, any security by
reason of such agreement, arrangement or understanding if the agreement,
arrangement or understanding to vote such security (1) arises solely from a
revocable proxy or consent

                                       57
<PAGE>   63


given to such Person in response to a public proxy or consent solicitation made
pursuant to, and in accordance with, the applicable rules and regulations
promulgated under the Exchange Act and (2) is not also then reportable on
Schedule 13D under the Exchange Act (or any comparable or successor report); or

                           (iii) such securities which are beneficially owned,
         directly or indirectly, by any other Person with which such Person or
         any of such Person's Affiliates or Associates has any agreement,
         arrangement or understanding for the purpose of acquiring, holding,
         voting or disposing of any securities of the Company;

                  (d) "Business Day" means any day other than a Saturday, Sunday
or day on which banks are permitted to close in the State of New York or in the
State of Delaware.

                  (e) "Company Disclosure Schedule" means a schedule of even
date herewith delivered by the Company to the Parent concurrently with the
execution of this Agreement, which, among other things, will identify exceptions
to the Company's representations and warranties contained in Article II by
specific section and subsection references;

                  (f) "Control" (including the terms "controlled by" and "under
common control with") means the possession, directly or indirectly or as trustee
or executor, of the power to direct or cause the direction of the management or
policies of a Person, whether through the ownership of stock, as trustee or
executor, by contract or credit arrangement or otherwise;

                  (g) "Court" means any court or arbitration tribunal of the
United States, any domestic state, or any foreign country, and any political
subdivision thereof.

                  (h) "Environmental Claim" means any claim, action, cause of
action, investigation or notice by any Person alleging potential liability
(including, without limitation, potential liability for investigatory costs,
cleanup costs, governmental response costs, natural resources damages, property
damages, personal injuries or penalties) arising out of, based on or resulting
from (a) the presence, release or disposal of any Hazardous Materials at any
location, whether or not owned or operated by the Company, or (b) circumstances
forming the basis of any violation, or alleged violation, of any Environmental
Law.

                  (i) "Environmental Laws" means any Law pertaining to: (i) the
protection of health, safety and the indoor or outdoor environment; (ii) the
conservation, management or use of natural resources and wildlife; (iii) the
protection or use of surface water and ground water; (iv) the management,
manufacture, possession, presence, use, generation, transportation, treatment,
storage, disposal, release, threatened release, abatement, removal, remediation
or handling of, or exposure to, any Hazardous Material; or (v) pollution
(including any release to air, land, surface water and ground water); and
includes, without limitation, the Comprehensive Environmental, Response,
Compensation, and Liability Act of 1980, as amended, and the Regulations
promulgated thereunder and the Solid Waste Disposal Act, as amended, 42 U.S.C.
ss. 6901 et seq.

                                       58
<PAGE>   64


                  (j) "Exchange Agent" means any bank or trust company organized
under the Laws of the United States or any of the states thereof and having a
net worth in excess of $100 million designated and appointed to act in the
capacities required under Section 1.12(a).

                  (k) "Governmental Authority" means any governmental agency or
authority (other than a Court) of the United States, any domestic state, or any
foreign country, and any political subdivision or agency thereof, and includes
any authority having governmental or quasi-governmental powers.

                  (l) "Hazardous Material" means any substance, chemical,
compound, product, solid, gas, liquid, waste, by-product, pollutant, contaminant
or material which is hazardous or toxic and is regulated under any Environmental
Law, and includes without limitation, asbestos or any substance containing
asbestos, polychlorinated biphenyls or petroleum (including crude oil or any
fraction thereof).

                  (m) "Intellectual Property Right" has the meaning ascribed to
such term in Section 2.19 of this Agreement.

                  (n) "Knowledge" means (i) in the case of an individual,
knowledge of a particular fact or other matter deemed to be possessed by the
individual if (a) such individual, after making due inquiry, is actually aware
of such fact or other matter or (ii) in the case of an entity (other than an
individual) such entity will be deemed to have "Knowledge" of a particular fact
or other matter if any individual who is serving, or has at any time served, as
a director, officer, partner, in-house counsel, patent counsel (with respect to
Intellectual Property Rights only), executor, or trustee of such Person (or in
any similar capacity) has, or at any time had, Knowledge of such fact or other
matter.

                  (o) "Law" means all laws, statutes and ordinances of any
Governmental Agency including all decisions of Courts having the effect of law
in each such jurisdiction;

                  (p) "Lien" means any mortgage, pledge, security interest,
attachment, encumbrance, lien (statutory or otherwise), option, conditional sale
agreement, right of first refusal, first offer, termination, participation or
purchase or charge of any kind (including any agreement to give any of the
foregoing); provided, however, that the term "Lien" shall not include (i)
statutory liens for Taxes, which are not yet due and payable or are being
contested in good faith by appropriate proceedings, (ii) statutory or common law
liens to secure landlords, lessors or renters under leases or rental agreements
confined to the premises rented, (iii) deposits or pledges made in connection
with, or to secure payment of, workers' compensation, unemployment insurance,
old age pension or other social security programs mandated under applicable
Laws, (iv) statutory or common law liens in favor of carriers, warehousemen,
mechanics and materialmen, to secure claims for labor, materials or supplies and
other like liens, and (v) restrictions on transfer of securities imposed by
applicable state and federal securities Laws;

                  (q) "Litigation" means any suit, action, arbitration, cause of
action, claim, complaint, criminal prosecution, investigation, demand letter,
governmental or other

                                       59
<PAGE>   65


administrative proceeding, whether at law or at equity, before or by any Court
or Governmental Authority, before any arbitrator or other tribunal;

                  (r) "Material Adverse Effect" means any fact, event, change,
circumstance or effect that is materially adverse to the business, condition
(financial or otherwise), operations, results of operations, assets, liabilities
or prospects of the (1) Company and its Subsidiaries, taken as a whole when such
term, is used in relation to the Company and/or the Subsidiaries or the context
otherwise so requires, provided that, the facts, events, changes, circumstances
or effects described in Section 8.4 of the Company Disclosure Schedule shall not
constitute a material adverse effect as to the Company or (2) the Parent and its
Subsidiaries, taken as a whole, when such term is used in relation to the Parent
or the context otherwise so requires.

                  (s) "Order" means any judgment, order, writ, injunction or
decree of any Court or Governmental Authority.

                  (t) "Person" means an individual, corporation, partnership,
association, trust, unincorporated organization, limited liability company,
other entity or group (as defined in Section 13(d)(3) of the Exchange Act);

                  (u) "Regulation" means any rule or regulation of any
Governmental Authority having the effect of Law.

                  (v) "Related Agreements" means the Stockholder Agreements,
Release Agreements, Consulting Agreements and Confidentiality Agreements.

                  (w) "Subsidiary" or "Subsidiaries" of the Company, the
Surviving Corporation, Parent or any other Person means any corporation,
partnership, joint venture, limited liability company or other legal entity of
which the Company, the Surviving Corporation, Parent or such other Person, as
the case may be, (either alone or through or together with any other Subsidiary)
owns, directly or indirectly, 50% or more of the stock or other equity interests
the holders of which are generally entitled to vote for the election of the
board of directors or other governing body of such corporation or other legal
entity.

                  (x) "Year 2000 Compliant" shall mean the design, writing and
testing of software owned or licensed by a Person (including existing products
and owned software and technology currently under development) used in the
operation of such Person's business as presently conducted , such that such
software will at all times (i) record, store, process, calculate, manage,
manipulate and present calendar dates falling before, on and after (and if
applicable, spans of time including) December 31, 1999, including, without
limitation, single-century formulas and multi-century formulas and (ii) create,
calculate, recognize, accept, display, store, retrieve, accent, compare, sort,
manipulate, or process any information dependent on or relating to such dates or
otherwise provide use of dates or date-dependent or date-related data,
including, but not limited to, century recognition, day-of-the week recognition,
leap years, date values and interfaces of date functionalities, without loss of
accuracy, functionality, data integrity and performance and will provide that
all date-related data and user interface functionalities and data fields include
the indication of century.

                                       60
<PAGE>   66


         8.5 INTERPRETATION. When a reference is made in this Agreement to
Sections, subsections, Schedules or Exhibits, such reference shall be to a
Section, subsection, Schedule or Exhibit to this Agreement unless otherwise
indicated. The words "include," "includes" and "including" when used herein
shall be deemed in each case to be followed by the words "without limitation."
The word "herein" and similar references mean, except where a specific Section
or Article reference is expressly indicated, the entire Agreement rather than
any specific Section or Article. The table of contents and the headings
contained in this Agreement are for reference purposes only and shall not affect
in any way the meaning or interpretation of this Agreement.

         8.6 SEVERABILITY. If any term or other provision of this Agreement is
invalid, illegal or incapable of being enforced by any rule of law, or public
policy, all other conditions and provisions of this Agreement shall nevertheless
remain in full force and effect so long as the economic or legal substance of
the transactions contemplated hereby is not affected in any manner materially
adverse to any party. Upon such determination that any term or other provision
is invalid, illegal or incapable of being enforced, the parties hereto shall
negotiate in good faith to modify this Agreement so as to effect the original
intent of the parties as closely as possible in an acceptable manner to the end
that transactions contemplated hereby are fulfilled to the extent possible.

         8.7 ENTIRE AGREEMENT. This Agreement (including all exhibits and
schedules hereto) constitutes the entire agreement and supersedes all prior
agreements and undertakings (other than the Confidentiality Agreement), both
written and oral, among the parties, or any of them, with respect to the subject
matter hereof and, except as otherwise expressly provided herein, are not
intended to confer upon any other Person any rights or remedies hereunder.

         8.8 ASSIGNMENT. This Agreement shall not be assigned by operation of
law or otherwise, except that Parent and Merger Sub may assign all or any of
their rights hereunder to any Affiliate provided that no such assignment shall
relieve the assigning party of its obligations hereunder.

         8.9 PARTIES IN INTEREST. This Agreement shall be binding upon and inure
solely to the benefit of each party hereto, and other than with respect to
Section 5.13 which the parties hereto intend to establish third party
beneficiary rights, nothing in this Agreement, express or implied, is intended
to or shall confer upon any other Person any right, benefit or remedy of any
nature whatsoever under or by reason of this Agreement.

         8.10 FAILURE OR INDULGENCE NOT WAIVER; REMEDIES CUMULATIVE. No failure
or delay on the part of any party hereto in the exercise of any right hereunder
will impair such right or be construed to be a waiver of, or acquiescence in,
any breach of any representation, warranty or agreement herein, nor will any
single or partial exercise of any such right preclude other or further exercise
thereof or of any other right. All rights and remedies existing under this
Agreement are cumulative to, and not exclusive to, and not exclusive of, any
rights or remedies otherwise available.

         8.11 GOVERNING LAW. This agreement and the agreements, instruments and
documents contemplated hereby will be governed by and construed in accordance
with the Law

                                       61
<PAGE>   67


of the State of Delaware (exclusive of conflicts of law principles) ("Delaware
Law"). Delaware Courts within the State of Delaware and, more particularly to
the fullest extent such Court shall have subject matter jurisdiction over the
matter, the Court of Chancery of the State of Delaware, will have exclusive
jurisdiction over any and all disputes between the parties hereto, whether in
law or equity, arising out of or relating to this Agreement and the agreements,
instruments and documents contemplated hereby. The parties consent to and agree
to submit to the jurisdiction of such Courts, provided, however, that such
consent to jurisdiction is solely for the purpose referred to in this Section
8.11 and shall not be deemed to be a general submission to the jurisdiction of
such Courts or in the State of Delaware other than for such purpose. Each of the
parties hereby waives, and agrees not to assert in any such dispute, to the
fullest extent permitted by applicable Delaware Law, any claim that (i) such
party is not personally subject to the jurisdiction of such Courts, (ii) such
party and such party's property is immune from any legal process issued by such
Courts or (iii) any Litigation commenced in such Courts is brought in an
inconvenient forum.

         8.12 COUNTERPARTS. This Agreement may be executed in one or more
counterparts, and by the different parties hereto in separate counterparts, each
of which when executed shall be deemed to be an original but all of which taken
together shall constitute one and the same agreement.


                [REMAINDER OF THIS PAGE INTENTIONALLY LEFT BLANK]


                                       62
<PAGE>   68
Confidential

         IN WITNESS WHEREOF, Parent, Merger Sub and the Company have caused this
Agreement and Plan of Merger to be executed as of the date first written above
by their respective officers thereunto duly authorized.

GELTEX PHARMACEUTICALS, INC.



By
  --------------------------
Name: Mark Skaletsky
Title: President and Chief
       Executive Officer


SHINE ACQUISITION SUB, INC.


By
  --------------------------
Name: Mark Skaletsky
Title: President and Chief
       Executive Officer


SUNPHARM CORPORATION


By
  --------------------------
Name: Stefan Borg
Title: President and Chief
       Executive Officer


                                       63
<PAGE>   69



                             Index of Defined Terms

<TABLE>
<S>                                                                                              <C>
Acquisition Amount..............................................................................................1.6
Acquisition Proposal.........................................................................................4.2(a)
Affiliates...................................................................................................8.4(a)
Agreement...................................................................................................Caption
Assumed Option...............................................................................................1.8(b)
Balance Sheet................................................................................................8.4(b)
Beneficial owner or "beneficially own".......................................................................8.4(c)
Blue Sky Laws................................................................................................2.5(b)
Bridge Loan..................................................................................................4.1(e)
Business Day.................................................................................................8.4(d)
DGCL.......................................................................................................Preamble
Certificate of Merger...........................................................................................1.2
Certificates................................................................................................1.12(c)
Code.........................................................................................................1.8(b)
Closing........................................................................................................1.14
Closing Average.................................................................................................1.6
Closing Date...................................................................................................1.14
Common Merger Consideration..................................................................................1.6(b)
Company.....................................................................................................Caption
Company Approvals............................................................................................2.1(a)
Company Common Shares......................................................................................Preamble
Company Disclosure Schedule......................................................................Article II Caption
Company Employee.............................................................................................5.6(a)
Company Options..............................................................................................1.8(b)
Company Plan(s).............................................................................................2.12(a)
Company Preferred Shares...................................................................................Preamble
Company Representatives......................................................................................4.2(a)
Company SEC Reports..........................................................................................2.8(a)
Company Shares Number........................................................................................1.6(c)
Company Warrants.............................................................................................1.8(d)
Company Stockholders' Meeting..................................................................................2.14
Confidentiality Agreement....................................................................................5.3(b)
Consenting Stockholder.........................................................................................5.13
Consulting Agreements........................................................................................6.2(e)
Control......................................................................................................8.4(f)
Court........................................................................................................8.4(g)
Delaware Law...................................................................................................8.11
DGCL.......................................................................................................Preamble
Dissenting Shares..............................................................................................1.17
Distribution Date............................................................................................1.6(d)
Effective Time..................................................................................................1.2
Environmental Claim..........................................................................................8.4(g)
</TABLE>

                                       64
<PAGE>   70


<TABLE>
<S>                                                                                                        <C>
Environmental Laws...........................................................................................8.4(h)
ERISA.......................................................................................................2.12(a)
ERISA Affiliate.............................................................................................2.12(a)
Exchange Act.................................................................................................2.5(b)
Exchange Agent...............................................................................................8.4(j)
Exchange Ratio Fraction......................................................................................1.6(c)
GAAP.........................................................................................................2.7(b)
Governmental Authority.......................................................................................8.4(k)
Hazardous Material...........................................................................................8.4(l)
HSR Act......................................................................................................2.5(b)
Injunction...................................................................................................6.1(e)
Insured Parties.............................................................................................5.12(b)
Intellectual Property Rights................................................................................2.19(a)
Knowledge....................................................................................................8.4(n)
Law..........................................................................................................8.4(o)
Lien.........................................................................................................8.4(p)
Litigation...................................................................................................8.4(q)
Material Adverse Effect......................................................................................8.4(r)
Material Agreements..........................................................................................2.6(a)
Subsidiary...................................................................................................8.4(x)
Measurement Date Average.....................................................................................1.6(b)
Merger.....................................................................................................Preamble
Merger Consideration.........................................................................................1.6(b)
Merger Sub..................................................................................................Caption
Merger Sub Common Stock.........................................................................................1.9
NOL.........................................................................................................2.17(m)
NASDAQ.......................................................................................................1.6(b)
Order........................................................................................................8.4(s)
Parent......................................................................................................Caption
Parent Approvals................................................................................................3.1
Parent Common Stock........................................................................................Preamble
Parent Right.................................................................................................1.6(d)
Parent Rights Agreement......................................................................................1.6(d)
Parent SEC Reports...........................................................................................3.6(a)
Parent Stipulated Expenses...................................................................................7.3(d)
Permits.........................................................................................................2.7
Person.......................................................................................................8.4(x)
Preferred Exchange Ratio.....................................................................................1.6(a)
Preferred Merger Consideration...............................................................................1.6(a)
Proxy Statement................................................................................................2.14
Registration Statement.........................................................................................2.14
Regulation...................................................................................................8.4(u)
Related Agreements...........................................................................................8.4(v)
Release Agreements.............................................................................................5.15
Rule 145 ......................................................................................................5.16
</TABLE>

                                       65
<PAGE>   71


<TABLE>
<S>                                                                                                         <C>
SEC..........................................................................................................2.7(a)
Securities Act...............................................................................................2.3(b)
Series A Preferred Stock ....................................................................................1.6(a)
Series B Preferred Stock ....................................................................................1.6(a)
Series A-1 Junior Participating Preferred Stock..............................................................1.6(d)
Stockholder Agreements.....................................................................................Preamble
Subsidiaries.................................................................................................8.4(w)
Subsidiary...................................................................................................8.4(w)
Subsidiary Approvals ........................................................................................2.1(b)
Superior Proposal............................................................................................4.2(b)
Surviving Corporation...........................................................................................1.1
Tax............................................................................................................2.17
Tax Returns....................................................................................................2.17
Taxes..........................................................................................................2.17
Termination Fee..........................................................................................7.3(b)(ii)
Topping Fee.............................................................................................7.3(b)(iii)
Warrants ....................................................................................................2.3(a)
WARN Act ...................................................................................................2.13(b)
Year 2000 Compliant..........................................................................................8.4(x)
1994 Plan....................................................................................................1.8(a)
1995 Plan....................................................................................................1.8(a)
1997 Unit Purchase Agreement.................................................................................1.8(f)
1997 Warrants..............................................................................................Preamble
</TABLE>


                                       66
<PAGE>   72



                                    EXHIBIT A

                          Form of Stockholder Agreement



                                _________, 1999

GelTex Pharmaceuticals, Inc.
9 Fourth Avenue
Waltham, Massachusetts 02154
Attention:  Mark Skaletsky

Re: Stockholder Agreement

Gentlemen:

         The undersigned (the "Stockholder") owns of record and beneficially the
number of shares (the "Shares") of common stock and/or preferred stock of
SunPharm Corporation, a Delaware corporation ("Company"), as set forth below. On
even date herewith, Company, GelTex Pharmaceuticals, Inc., a Delaware
corporation ("Parent") and Shine Acquisition Sub, Inc., a Delaware corporation
and a newly organized wholly owned subsidiary of Company ("Merger Sub"), entered
into an Agreement and Plan of Merger (the "Agreement") with respect to the
merger (the "Merger") of Merger Sub with and into Company. Such Company common
stock and preferred stock will be converted in the Merger into Shares of the
common stock, $.01 par value per share, of Parent (the "Parent Common Stock").
The Stockholder wishes to facilitate the proposed Merger and acknowledge that
the proposed Merger will benefit the Stockholder.

         In consideration of the foregoing, and for other good and valuable
consideration, the receipt and sufficiency of which are hereby acknowledged, and
intending to be legally bound hereby, the Stockholder agrees as follows:

         1. Standstill. Except in connection with the Merger, the Stockholder
will not offer, sell, contract to sell, transfer or otherwise dispose of, or
grant any option to purchase, or convert, any of the Shares until the earlier of
December 31, 1999, or the termination of the Agreement in accordance with its
terms. As security for the Stockholder's obligations under this paragraph, the
Stockholder hereby assigns to and grants to Parent a lien upon and a security
interest in the Shares.

                                       67
<PAGE>   73
Confidential

         2. Proxy.

                  (a) As further security for the Stockholder's obligations
under paragraph 1, the Stockholder hereby revokes any previous proxies relating
to the Shares and irrevocably appoints Mark Skaletsky, President and Chief
Executive Officer of Parent and Paul J. Mellett, Jr., Vice President and Chief
Financial Officer of Parent, and each of them, attorneys and proxies, with power
of substitution in each of them, of the Stockholder to attend, represent, vote
the Shares and act on behalf of the Stockholder in favor of the Merger on the
terms set forth in the Agreement as executed (with such changes as are not
material to the rights of the Stockholder in the Merger), and with respect to
other matters in connection therewith, at any meeting (and at all adjournments,
continuations or postponements, thereof) (the "Meeting") of the stockholders of
Company at which the Merger is presented for approval of such stockholders
(including executing waivers and consents in connection with the Merger), and
otherwise to act for the Stockholder in the same manner and with the same effect
as if the Stockholder were personally present at such Meeting and voting the
Shares or personally acting on any matters in connection with the Merger
submitted to the stockholders of Company for approval or consent.

                  (b) The Stockholder authorizes such proxies to substitute any
other person or persons to act hereunder, to revoke any such substitution and to
file this proxy and any such substitution or revocation with the Secretary of
Company.

                  (c) THIS PROXY IS IRREVOCABLE AND COUPLED WITH AN INTEREST AND
SHALL TERMINATE ON THE EARLIER OF DECEMBER 31, 1999 OR THE TERMINATION OF THE
AGREEMENT PURSUANT TO THE TERMS THEREOF.

         3. Representations and Warranties by Stockholder. The Stockholder
represents and warrants to Parent that:

                  (a) the Stockholder has all necessary power and authority to
execute this letter agreement including the proxy appointment contained herein;

                  (b) this letter agreement and proxy has been duly executed and
delivered by the Stockholder and constitutes a valid and binding agreement of
the Stockholder, enforceable in accordance with its terms; and

                  (c) neither the execution nor delivery of this letter
agreement and proxy by the Stockholder will (i) require the consent, waiver,
approval, license or authorization, or any filing with, any person or public
authority, (ii) with or without the giving of notice or the lapse of time, or
both, conflict with or constitute a violation of, or default under, or give rise
to any right of acceleration under any indenture, contract, commitment,
agreement, arrangement or other instrument of any kind to which the Stockholder
is a party or by which the Stockholder is bound, or (iii) violate any applicable
law, rule, regulation, judgment, order or degree of any governmental
instrumentality or court having jurisdiction over the Stockholder.

                                       68
<PAGE>   74


         4. Miscellaneous.

                  (a) The Stockholder will not take any action that would
prevent or frustrate Parent's rights hereunder.

                  (b) The Stockholder acknowledges receipt of the following
documents: (i) Parent's Annual Report on Form 10-K for the year ended December
31, 1998; and (ii) Parent's 1999 Annual Report to Stockholders.

         IN WITNESS WHEREOF, the Stockholder has executed this agreement and
proxy as of the date and year first above written.

                                        STOCKHOLDER:


                                        _____________________________

                                        Number of Shares of
                                        Common Stock ________________

                                        Number of Shares of Series A
                                        Preferred Stock _____________

                                        Number of Shares of Series B
                                        Preferred Stock _____________


                                       69
<PAGE>   75
Confidential


                                    EXHIBIT B

                                     FORM OF

                              CERTIFICATE OF MERGER

                                       OF

               SHINE ACQUISITION SUB, INC., A DELAWARE CORPORATION

                                  WITH AND INTO

                  SUNPHARM CORPORATION, A DELAWARE CORPORATION

                              ********************

         Pursuant to Section 251 of the General Corporation Law of the State of
Delaware, the undersigned corporations organized and existing under and by
virtue of the General Corporation Law of the State of Delaware, DO HEREBY
CERTIFY:

         FIRST: That the name and state of incorporation of each of the
constituent corporations are as follows:

<TABLE>
<CAPTION>
         NAME                                            STATE OF INCORPORATION
         ----                                            ----------------------
<S>                                                      <C>
1. Shine Acquisition Sub, Inc.                                   Delaware

2. SunPharm Corporation                                          Delaware
</TABLE>

         SECOND: That an Agreement and Plan of Merger dated August 13, 1999 by
and among Geltex Pharmaceuticals, Inc., Shine Acquisition Sub, Inc. and SunPharm
Corporation has been approved, adopted, certified, executed and acknowledged by
each of the constituent corporations in accordance with the requirements of
Section 251 of the General Corporation Law of the state of Delaware.

         THIRD: The name of the surviving corporation of the merger is SunPharm
Corporation (the "Surviving Corporation").

         FOURTH: The Certificate of Incorporation of the Surviving Corporation
shall be Amended and Restated in its entirety to read as set forth in Exhibit A
attached hereto.

                                       70
<PAGE>   76


         FIFTH: That the executed copy of the Agreement and Plan of Merger is on
file at the principal place of business of the Surviving Corporation. The
address of the principal place of business of the Surviving Corporation is:

                                    The Veranda, Suite 301
                                    814 Highway A-1A
                                    Ponte Vedra Beach, Florida  32082

         SIXTH: That a copy of the Agreement and Plan of Merger will be
furnished by the Surviving Corporation, on request and without cost, to any
stockholder of the constituent corporations.

         IN WITNESS WHEREOF, the undersigned, being the President of Shine
Acquisition Sub, Inc., does hereby execute this Certificate of Merger and so
certifies, affirms and acknowledges under penalties of perjury that this is his
free act and deed and that the facts stated herein are true, this ___________
______, 1999.


                                            SHINE ACQUISITION SUB, INC.


                                            By:________________________________
                                                     Mark Skaletsky, President

         IN WITNESS WHEREOF, the undersigned, being the President of SunPharm
Corporation, does hereby execute this Certificate of Merger and so certifies,
affirms and acknowledges under penalties of perjury that this is his free act
and deed and that the facts stated herein are true, this ______________, 1999.


                                            SUNPHARM CORPORATION



                                            By:_____________________________
                                                     Stefan Borg, President

                                       71
<PAGE>   77
Confidential
                                                                       EXHIBIT A

                              AMENDED AND RESTATED

                          CERTIFICATE OF INCORPORATION

                                       OF

                              SUNPHARM CORPORATION


         FIRST: The name of the corporation (hereinafter called the
"Corporation") is SunPharm Corporation.

         SECOND: The address, including street, number, city, and county, of the
registered office of the corporation in the State of Delaware is 1013 Centre
Road, Wilmington, Delaware, New Castle County 19801; and the name of the
registered agent of the corporation in the State of Delaware at such address is
Corporation Service Company.

         THIRD: The nature of the business and the purposes to be conducted and
promoted by the Corporation, shall be any lawful business, to promote any lawful
purpose, and to engage in any lawful act or activity for which corporations may
be organized under the General Corporation law of the State of Delaware.

         FOURTH: The total number of shares of stock which the Corporation shall
have authority to issue is as follows:

         3,000 shares of Common Stock, $0.01 par value.

         FIFTH:  The Corporation shall have perpetual existence.

         SIXTH: Whenever a compromise or arrangement is proposed between this
Corporation and its creditors or any class of them and/or between this
Corporation and its stockholders or any class of them, any court of equitable
jurisdiction within the State of Delaware may, on the application in a summary
way of this Corporation or of any creditor or stockholder thereof or on the
application of any receiver or receivers appointed for this Corporation under
the provisions of Section 291 of Title 8 of the Delaware Code or on the
application of trustees in dissolution or of any receiver or receivers appointed
for this Corporation under the provisions of Section 279 of Title 8 of the
Delaware Code order a meeting of the creditors or class of creditors, and/or of
the stockholders or class of stockholders of this Corporation, as the case may
be, to be summoned in such manner as the said court directs. If a majority in
number representing three-fourths in value of the creditors or class of
creditors, and/or of the stockholders or class of stockholders of this
Corporation, as the case may be, agree to any compromise or arrangement and to
any reorganization of this Corporation as a consequence of such compromise or
arrangement, the said compromise or arrangement and the said reorganization
shall, if sanctioned by the court to which

                                       72
<PAGE>   78


the said application has been made, be binding on all the creditors or class of
creditors, and/or on all the stockholders or class of stockholders, of this
Corporation, as the case may be, and also on this Corporation.

         SEVENTH: For the management of the business and for the conduct of the
affairs of the Corporation, and in further definition, limitation and regulation
of the powers of the Corporation and of its directors and of its stockholders or
any class thereof, as the case may be, it is further provided that:

         1. The business of the Corporation shall be conducted by the officers
of the Corporation under the supervision of the Board of Directors.

         2. The number of directors which shall constitute the whole Board of
Directors shall be fixed by, or in the manner provided in, the By-Laws. No
election of Directors need be by written ballot.

         3. The Board of Directors of the Corporation may adopt, amend or repeal
the By-Laws of the Corporation at any time after the original adoption of the
By-Laws according to Section 109 of the General Corporation Law of the State of
Delaware; provided, however, that any amendment to provide for the
classification of directors of the corporation for staggered terms pursuant to
the provisions of subsection (d) of Section 141 of the General Corporation Law
of the State of Delaware shall be set forth in an amendment to this Certificate
of Incorporation, in an initial By-Law, or in a By-Law adopted by the
stockholders of the Corporation entitled to vote.

         EIGHTH: (a) The Corporation may, to the fullest extent permitted by
Section 145 of the General Corporation Law of the State of Delaware, as the same
may be amended and supplemented, indemnify (and advance expenses to) any and all
persons whom it shall have power to indemnify under said section from and
against any and all of the expenses, liabilities or other matters referred to in
or covered by said section, and the indemnification provided for herein shall
not be deemed exclusive of any other rights to which a person indemnified may be
entitled under any By-Law, agreement, vote of stockholders or disinterested
directors or otherwise, both as to action in his official capacity and as to
action in another capacity while holding such office, and shall continue as to a
person who has ceased to be director, officer, employee or agent and shall inure
to the benefit of the heirs, executors and administrators of such a person. No
amendment to or repeal of this paragraph (a) of this Article Eight shall
adversely affect any right or protection of a person existing at the time of, or
increase the liability of any person with respect to any acts or omissions of
such person occurring prior to such amendment or repeal.

         (b) No director shall be personally liable to the Corporation or its
stockholders for monetary damages for any breach of fiduciary duty by such
director as a director. Notwithstanding the foregoing sentence, a director shall
be liable to the extent provided by applicable law (i) for breach of the
director's duty of loyalty of the Corporation or its stockholders, (ii) for acts
or omissions not in good faith or which involve intentional misconduct

                                       73
<PAGE>   79


or a knowing violation of law, (iii) pursuant to Section 174 of the Delaware
General Corporation Law or (iv) for any transaction from which the director
derived an improper personal benefit. No amendment to or repeal of this
paragraph (b) of this Article Eight shall apply to or have any effect on the
liability or alleged liability of any director of the Corporation for or with
respect to any acts or omissions of such director occurring prior to such
amendment or repeal.

         NINTH: From time to time any of the provisions of this Certificate of
Incorporation may be amended, altered or repealed, and other provisions
authorized by the laws of the State of Delaware at the time in force may be
added or inserted in the manner and at the time prescribed by said laws, and all
rights at any time conferred upon the stockholders of the Corporation by this
Certificate of Incorporation are granted subject to the provisions of this
Article Nine.


                                       74
<PAGE>   80




                                    EXHIBIT C

                            FORM OF RELEASE AGREEMENT


         Reference is made to the Agreement and Plan of Merger dated as of
August 13, 1999 (the "Merger Agreement") by and among GelTex Pharmaceuticals,
Inc., a Delaware corporation ("Parent"), Shine Acquisition Sub, Inc., a Delaware
corporation and a wholly owned subsidiary of Parent ("Merger Sub") and SunPharm
Corporation, a Delaware corporation (the "Company'). All capitalized terms used,
but not defined herein shall have the meanings ascribed to such terms in the
Merger Agreement.

         As an inducement for Parent and Merger Sub to consummate the
transactions contemplated by the Merger Agreement and for other good and
valuable consideration, the receipt and adequacy of which is hereby
acknowledged, effective as of the Effective Time, the undersigned (the
"Releasor") on his, her or its behalf and on behalf of his, her or its (i)
heirs, executors, administrators, agents, successors and assigns or (ii)
predecessors, parents, subsidiaries, affiliates and other related entities, as
well as any current or former benefit plan administrators, and their respective
trustees, officers, directors, stockholders or members (whether their ownership
interests are held directly or indirectly), partners, agents, attorneys,
employees, successors and assigns (the "Releasor Persons"), as applicable,
hereby irrevocably and unconditionally releases, waives and discharges the
Company, Parent and Merger Sub and their predecessors, parents, subsidiaries,
affiliates and other related entities, and all of their respective, past,
present and future officers, directors, stockholders, affiliates, agents,
representatives, successors and assigns, other than the Releasor and any
Releasor Person (collectively, the "Released Parties"), from any and all
actions, causes of action, suits, debts, dues, sums of money, accounts, bonds,
bills, covenants, contracts, controversies, agreements, promises, variances,
trespasses, damages, judgments, executions, claims and demands of every type and
nature whatsoever, known or unknown, in law or equity (each a "Claim" and
collectively, the "Claims") relating to, arising out of or in connection with
the Company, its business and/or assets, including any Claims relating to,
arising out of or resulting from the Releasor's status, relationship,
affiliation, rights, obligations and/or duties as a director, officer, employee
or securityholder of the Company, for all periods through the time immediately
prior to the Effective Time.

         The undersigned hereby represents and warrants that in his, her or its
capacity as a securityholder of the Company, he, she or it has no knowledge of
any claims that he, she or it may have against the Released Parties.

         This Release shall terminate upon the termination of the Merger
Agreement pursuant to the terms thereof.


                                       75
<PAGE>   81




         IN WITNESS WHEREOF, the undersigned has duly executed this Release and
Waiver as of this ____ day of ________________, 1999.


                                                  ______________________________

                                                  Name:_________________________
                                                                (Print)


                                       76
<PAGE>   82


                                    EXHIBIT D

                           FORM OF AFFILIATE AGREEMENT


                                                             _________ ___, 1999


GelTex Pharmaceuticals, Inc.
Shine Acquisition Sub, Inc.
9 Fourth Avenue
Waltham, Massachusetts  02154
Attention:  Mark Skaletsky

SunPharm Corporation
The Veranda, Suite 301
814 Highway A-1A
Ponte Vedra Beach, Florida  32082
Attention:  Stefan Borg

Ladies and Gentlemen:

         I/We have been advised that I/we might be considered to be an
"affiliate" of SunPharm Corporation (the "Company") for purposes of Rule 145
("Rule 145") under the Securities Exchange Act of 1933, as amended (the
"Securities Act"), as promulgated by the Securities and Exchange Commission (the
"SEC").

         GelTex Pharmaceuticals, Inc. ("Parent"), Shine Acquisition Sub, Inc.
("Merger Sub") and the Company have entered into an Agreement and Plan of Merger
dated as of the 13th day of August, 1999 (the "Plan of Merger"). Upon
consummation of the transactions contemplated by the Plan of Merger (the
"Merger"), I/we will receive shares of capital stock of Parent for all of the
shares of capital stock of the Company owned by me/us or as to which I/we may be
deemed a beneficial owner. I/We own _____________ shares of the common stock,
$.0001 par value per share, of the Company (the "Company's Common Stock") and/or
__________ shares of Series A Redeemable Convertible Preferred Stock, $.001 par
value per share and/or _________ shares of Series B Redeemable Convertible
Preferred Stock, $.001 par value per share (collectively, the "Preferred
Stock"). The Company's Common Stock and the Company's Preferred Stock will be
converted in the Merger into shares of the common stock, $.01 par value per
share, of Parent (the "Parent Common Stock") as described in the Plan of Merger.
The shares of Parent Common Stock received by me/us in the Merger are
hereinafter collectively referred to as the "Exchange Stock". This agreement is
hereinafter referred to as the "Affiliate Agreement".

                                       77
<PAGE>   83


         I/We represent and warrant to, and agree with, Parent, Merger Sub and
the Company that:

         A. I/We have read this Affiliate Agreement and the Plan of Merger and
have discussed their requirements and other applicable limitations upon my/our
ability to sell, transfer or otherwise dispose of the Exchange Stock, to the
extent I/we felt necessary, with my/our counsel or counsel for the Company.

         B. I/We understand that my/our resale of Exchange Stock issued to me/us
in the Merger will be subject to certain restrictions on transfer in accordance
with Rule 145 under the Securities Act, and in connection therewith I/we agree
not to offer, sell, pledge, transfer or otherwise dispose of any of such shares
of Exchange Stock unless at such time either: (i) such transaction shall be
permitted pursuant to the provisions of Rule 145; (ii) I/we shall have furnished
to the Parent an opinion of counsel, satisfactory to the Parent, to the effect
that no registration under the Securities Act would be required in connection
with the proposed offer, sale, pledge transfer or other disposition; (iii) a
registration statement under the Securities Act covering the proposed offer,
sale, pledge, transfer or other disposition shall be effective under the
Securities Act; or (iv) an authorized representative of the SEC shall have
rendered written advice to me/us to the effect that the SEC will take no action,
or that the staff of the SEC will not recommend that the SEC take action, with
respect to the proposed offer, sale, pledge transfer or other disposition if
consummated.

         C. I/We understand that all certificates representing the Exchange
Stock delivered to me/us pursuant to the Merger shall, until the occurrence of
one of the events referred to in paragraph B. above, bear a legend substantially
as follows:

         "The shares represented by this certificate may not be offered, sold,
pledged, transferred or otherwise disposed of except in accordance with the
requirements of Rule 145 of the Securities Act of 1933, as amended."

         D. I/We also understand and agree that the Parent, in its discretion
and in a manner consistent with the legend set forth above, may cause stop
transfer orders to be placed with its transfer agent with respect to the
certificates for the shares of Exchange Stock which are required to bear the
foregoing legend.

         E. To the extent I/we am/are an "affiliate" of the Company solely by
virtue of reasons other than being an officer or a director of the Company, I/we
agree to comply with the prohibition described in Section 4.2 of the Agreement.

         It is understood and agreed that this Affiliate Agreement shall
terminate and be of no further force and effect if the Plan of Merger is
terminated pursuant to the terms thereof.

         The agreements made by me/us in the foregoing paragraphs are on the
understanding that Parent has agreed, in Section 5.16(b) of the Plan of Merger,
that at all times during the two (2) year period beginning on the Closing Date
(as such term is defined in the Plan of

                                       78
<PAGE>   84


Merger) to file with the SEC or otherwise make publicly available all
information required under Rule 144(c)(1) promulgated under the Securities Act,
to the extent available to you without unreasonable effort or expense, necessary
to enable me/us to resell shares under the provisions of paragraph (d) of Rule
145.


                                       79
<PAGE>   85


         This Affiliate Agreement shall be binding on my/our heirs, legal
representatives and successors.

                                                              Very truly yours,



                                                              Name:


                                       80
<PAGE>   86



                                    EXHIBIT E

               FORM OF OPINION OF COUNSEL TO SUNPHARM CORPORATION

         1. The Company is a corporation duly organized, validly existing and in
good standing under the laws of its state of incorporation, and has the
corporate power and authority to enter into and perform the Agreement. The
Company is duly qualified and in good standing as a foreign corporation
authorized to transact business in the State of Florida. The Company has all
requisite corporate power and authority to own or lease and to operate its
properties and assets and to conduct its business as presently conducted.

         2. The execution and delivery of the Agreement and the consummation of
the transactions contemplated thereby have been duly authorized by all necessary
corporate action on the part of the Company. The Company has duly executed and
delivered the Agreement, and the Agreement constitutes the valid and binding
obligation of the Company, enforceable against it in accordance with its terms,
except as enforceability may be limited by bankruptcy, insolvency,
reorganization, moratorium or similar laws of general application affecting the
rights and remedies of creditors and by general principles of equity.

         3. At __________, 1999, the authorized capital stock of the Company
consisted solely of: (i) _________ shares of Preferred Stock, $.001 par value
per share, of which (a) ______ shares have been designated Series A Preferred
Stock, ______ shares of which are issued and outstanding and (b) ______ shares
have been designated Series B Preferred Stock, ______ shares of which are issued
and outstanding, and (ii) ____________ shares of the Company Common Stock,
$.0001 par value per share, of which _________ shares are issued and
outstanding. All warrants issued by the Company (the "Warrants") pursuant to
that Unit Purchase Agreement dated March 28, 1997 (the "1997 Unit Purchase
Agreement") have been exchanged for shares of the Company Common Stock and the
Warrant Agreement has been terminated prior to the date hereof, and no holder or
record or beneficial owner of any such Warrant has any basis for a claim or
cause of action against the Company by reason of such exchange of Warrants and
termination of the Warrant Agreement. All stock options granted by the Company
under its Amended and Restated 1994 Stock Option Plan (the "1994 Plan") have
either been exercised or terminated in accordance with the provisions of the
1994 Plan and the option agreements thereunder, and no option holder or
participant in the 1994 Plan has any basis under the 1994 Plan or the relevant
option agreement for a claim or cause of action against the Company by reason of
such termination. To our knowledge, except as set forth in the Agreement or the
Company Disclosure Schedule, there are no (i) outstanding or authorized
subscriptions, warrants, options or other rights granted by the Company to
purchase or acquire, or preemptive rights with respect to the issuance or sale
of, the capital stock of the Company or which obligate the Company to issue any
additional shares of its capital stock or any securities convertible into or
evidencing the right to subscribe for any shares of its capital stock, (ii)
other securities of the Company directly or indirectly convertible into or
exchangeable for shares of capital stock of the Company, (iii) restrictions on
the transfer of the Company's capital stock (other than those imposed by
relevant state and federal securities laws), (iv) special voting rights with
respect to the capital stock of the Company, or (v) stock appreciation, phantom
stock or similar rights

                                       81
<PAGE>   87


granted by the Company. To our knowledge, except as set forth in the Agreement
or the Company Disclosure Schedule, no holders of securities of the Company have
rights to require the Company to register such securities for sale.

         4. Except as set forth in the Agreement or the Company Disclosure
Schedule, to the best of our knowledge, there are no claims, actions, suits,
arbitrations, proceedings or investigations pending or threatened against or
involving the Company.

         5. Except for (i) the filing of the Certificate of Merger and other
appropriate merger documents, if any, as required by the DGCL and (ii) such
filings, notices, permits, consents and approvals as have been made, given or
obtained, the execution, delivery and performance of the Agreement by the
Company will not: (a) violate any provision of the Certificate of Incorporation
or by-laws of the Company; (b) violate, conflict with, result in modification of
the effect of, or otherwise give any other contracting party the right to
terminate, or constitute (or with notice or lapse of time or both constitute) a
default under, any agreement or instrument known to us to which the Company is a
party or to which it may be subject; (c) violate any law or regulation or, to
the best of our knowledge, any judgment, decree or order of any court,
arbitrator or governmental or regulatory body applicable to the Company; or (d)
require any filing with, notice to, or permit, consent or approval of, any
governmental or regulatory body, excluding from the foregoing clauses (b), (c)
and (d) any exceptions to the foregoing that, in the aggregate, would not have a
material adverse effect on the business of the Company or on the ability of the
Company to consummate the transactions contemplated by the Agreement.

         6. Assuming that Merger Sub has complied with all relevant provisions
of the DGCL, upon the filing and acceptance of the Certificate of Merger with
the Secretary of State of the State of Delaware, the Merger will become
effective under the DGCL at the time specified in the Certificate of Merger.

         7. The Registration Statement has become effective under the Securities
Act and, to the best of our knowledge, no stop order suspending the
effectiveness of the Registration Statement or preventing the use of the Proxy
Statement has been issued and no proceedings for that purpose have been
instituted or are pending or threatened.

         We have acted as counsel to the Company in connection with the
preparation of the Registration Statement of Parent filed with the Securities
and Exchange Commission under the Securities Act and the Proxy
Statement/Prospectus contained therein. The Registration Statement in the form
in which it was declared effective under the Securities Act and the Proxy
Statement/Prospectus in the form filed pursuant to Rule 424(b) under the
Securities Act are herein referred to as the "Registration Statement" and "Proxy
Statement/Prospectus", respectively. We have not verified, and are not passing
upon and do not assume any responsibility for the accuracy, completeness or
fairness of the statements contained in the Registration Statement and the Proxy
Statement/Prospectus, and we have not participated in the preparation of the
documents incorporated by reference therein. We have, however, generally
reviewed and discussed such statements with certain officers of the Company and
with you and your counsel. In the course of this review and discussion, and
solely with respect to the

                                       82
<PAGE>   88


Company, no facts have come to our attention which have caused us to believe
that: (i) the Registration Statement, at the time it became effective or on the
date hereof contained or contains an untrue statement of a material fact
relating to the Company or omitted or omits to state a material fact relating to
the Company required to be stated therein or necessary to make the statements
therein relating to the Company not misleading or (ii) the Proxy
Statement/Prospectus at the time the Registration Statement became effective,
included or includes an untrue statement of a material fact relating to the
Company or omitted or omits to state a material fact relating to the Company
necessary to make the statements therein relating to the Company, in the light
of the circumstances under which they were made, not misleading, it being
understood that we do not express any opinion or confirmation with respect to
the operating statistics, financial statements, schedules and other financial
and statistical data included in the Registration Statement or Proxy
Statement/Prospectus or omitted therefrom, or any information or its compliance
as to form concerning or furnished by Parent or Merger Sub.


                                       83
<PAGE>   89


                                    EXHIBIT F

           FORM OF OPINION OF COUNSEL TO GELTEX PHARMACEUTICALS, INC.
                        AND SHINE ACQUISITION SUB, INC.

         1. Each of Parent and Merger Sub is a corporation duly incorporated,
validly existing and in good standing under the laws of its state of
incorporation, and has the corporate power and authority to enter into and
perform the Agreement.

         2. The execution and delivery of the Agreement and the consummation of
the transactions contemplated thereby have been duly authorized by all necessary
corporate action on the part of Parent and Merger Sub. Each of Parent and Merger
Sub has duly executed and delivered the Agreement, and the Agreement constitutes
the valid and binding obligation of Parent and Merger Sub, enforceable against
each in accordance with its terms, except as enforceability may be limited by
bankruptcy, insolvency, reorganization, moratorium or similar laws of general
application affecting the rights and remedies of creditors and by general
principles of equity.

         3. The shares of Parent Common Stock to be issued in the Merger have
been duly authorized by all necessary corporate action on the part of Parent
and, when issued in the Merger pursuant to the terms of the Agreement, such
shares will be validly issued, fully paid and nonassessable and not subject to
any preemptive rights or to any restriction on transfer imposed by the
Certificate of Incorporation or by-laws of Parent.

         4. Based solely on the SEC Reports of Parent, there are no claims,
actions, suits, arbitrations, proceedings or investigations pending or
threatened against or involving Parent or Merger Sub that individually or in the
aggregate which, if adversely determined, are reasonably likely to: (i)
materially restrict or interfere with the Agreement or any transaction
contemplated thereby or (ii) materially impair or preclude the ability of Parent
or Merger Sub to consummate the Merger or the transactions contemplated by the
Agreement.

         5. Except for (i) the filing of the Certificate of Merger and other
appropriate merger documents, if any, as required by the DGCL and (ii) such
filings, notices, permits, consents and approvals as have been made, given or
obtained, the execution, delivery and performance of the Agreement by each of
Parent and Merger Sub will not: (a) violate any provision of the Certificate of
Incorporation or by-laws of Parent or Merger Sub; (b) violate, conflict with,
result in modification of the effect of, or otherwise give any other contracting
party the right to terminate, or constitute (or with notice or lapse of time or
both constitute) a default under, any agreement or instrument known to us to
which either of Parent or Merger Sub is a party or to which either of them may
be subject; (c) violate any law or regulation or, to the best of our knowledge,
any judgment, decree or order of any court, arbitrator or governmental or
regulatory body applicable to either of Parent or Merger Sub; or (d) require any
filing with, notice to, or permit, consent or approval of, any governmental or
regulatory body, excluding from the foregoing clauses (b), (c) and (d) any
exceptions to the foregoing that, in the aggregate, would not have a material
adverse

                                       84
<PAGE>   90


effect on the ability of Parent or Merger Sub to consummate the transactions
contemplated by the Agreement.

         6. Assuming that the Company has complied with all relevant provisions
of the DGCL, upon the filing and acceptance of the Certificate of Merger with
the Secretary of State of the State of Delaware, the Merger will become
effective under the DGCL at the time specified in the Certificate of Merger.

         7. The Registration Statement has become effective under the Securities
Act and, to the best of our knowledge, no stop order suspending the
effectiveness of the Registration Statement or preventing the use of the Proxy
Statement has been issued and no proceedings for that purpose have been
instituted or are pending or threatened.

         We have acted as counsel to Parent and Merger Sub in connection with
the preparation of the Registration Statement of Parent filed with the
Securities and Exchange Commission under the Securities Act and the Proxy
Statement/Prospectus contained therein. The Registration Statement in the form
in which it was declared effective under the Securities Act and the Proxy
Statement/Prospectus in the form filed pursuant to Rule 424(b) under the
Securities Act are herein referred to as the "Registration Statement" and "Proxy
Statement/Prospectus", respectively. We have not verified, and are not passing
upon and do not assume any responsibility for the accuracy, completeness or
fairness of the statements contained in the Registration Statement and the Proxy
Statement/Prospectus, and we have not participated in the preparation of the
documents incorporated by reference therein. We have, however, generally
reviewed and discussed such statements with certain officers of Parent and
Merger Sub and with you and your counsel. In the course of this review and
discussion, and solely with respect to Parent and Merger Sub, no facts have come
to our attention which have caused us to believe that: (i) the Registration
Statement, at the time it became effective or on the date hereof contained or
contains an untrue statement of a material fact relating to Parent or Merger Sub
or omitted or omits to state a material fact relating to Parent or Merger Sub
required to be stated therein or necessary to make the statements therein
relating to Parent or Merger Sub not misleading or (ii) the Proxy
Statement/Prospectus at the time the Registration Statement became effective,
included or includes an untrue statement of a material fact relating to Parent
or Merger Sub or omitted or omits to state a material fact relating to Parent or
Merger Sub necessary to make the statements therein relating to Parent or Merger
Sub, in the light of the circumstances under which they were made, not
misleading, it being understood that we do not express any opinion or
confirmation with respect to the operating statistics, financial statements,
schedules and other financial and statistical data included in the Registration
Statement or Proxy Statement/Prospectus or omitted therefrom, or any information
or its compliance as to form concerning or furnished by the Company.


                                       85

<PAGE>   1
                                                                    Exhibit 10.4


                                                             From the Office of:
                                  STANDARD FORM              Burns & Levinson
                          PURCHASE AND SALE AGREEMENT        125 Summer Street
                                                             Boston, MA 02110

1.       PARTIES AND MAILING ADDRESSES
         (fill in)

         This 26th day of July, 1999, Barry L. Solar and Robert L. Solar, as
         Trustees of 211 Second Avenue Realty Trust u/d/t dated March 8, 1988
         and recorded with Middlesex South District Registry of Deeds, and not
         individually hereinafter called the SELLER, agrees to SELL and Geltex
         Pharmaceuticals, Inc., a Delaware corporation hereinafter called the
         BUYER or PURCHASER, agrees to BUY, upon the terms hereinafter set
         forth, the following described premises: (the "Premises"):

2.       DESCRIPTION
         (fill in and include title reference)

         The land area of approximately 4.737 acres together with the
         improvements thereon containing approximately 19,200 square feet of
         building area known and numbered as 211 Second Avenue, Waltham,
         Massachusetts, as shown on the Plan annexed hereto as Exhibit A (as
         affected by the taking/layout

3.       BUILDINGS, STRUCTURES, IMPROVEMENTS, FIXTURES
         {fill in or delete)

         Included in the sale as a part of said premises are the buildings,
         structures, and improvements now thereon, and the fixtures belonging to
         the SELLER and used in connection therewith including, if any, all
         wall-to-wall carpeting, drapery rods, automatic garage door openers,
         venetian blinds, window shades, screens, screen doors, storm windows
         and doors, awnings, shutters, furnaces, heaters, heating equipment,
         stoves, ranges, oil and gas burners and fixtures appurtenant thereto,
         hot water heaters, plumbing and bathroom fixtures, garbage disposers,
         electric and other lighting fixtures, mantels, outside television
         antennas, fences, gates, trees, shrubs, plants, and, ONLY IF BUILT IN,
         refrigerators, air conditioning equipment, ventilators, dishwashers,
         washing machines and dryers;

4.       TITLE DEED
         (fill in)
         * Include here by specific reference any restrictions, easements,
           rights and obligations in party walls not included in (b), leases,
           municipal and other liens, other encumbrances, and make provision to
           protect SELLER against BUYER's breach of SELLER's covenants in
           leases, where necessary.

         Said premises are to be conveyed by a good and sufficient quitclaim
         deed running to the BUYER, or to the nominee designated by the BUYER by
         written notice to the SELLER at least seven days before the deed is to
         be delivered as herein provided, and said deed shall convey a good and
         clear record and marketable title thereto, free from encumbrances,
         except
           (a) Provisions of existing building and zoning laws;
           (b) Existing rights and obligations in party walls which are not the
               subject of written agreement;
           (c) Such taxes for the then current year as are not due and payable
               on the date of the delivery of such deed;
           (d) Any liens for municipal betterments assessed after the date of
               this agreement;***
           (e) Easements, restrictions and reservations of record, if any, so
               long as the same do not prohibit or materially interfere with the
               current use of said premises;
           (f) The leases referred to in Exhibit B and any monthly
               tenancy-at-will of Evergreen Solar for a period after the
               termination of its lease referred to in Exhibit B
           (g) Taking for the layout of Second Avenue

5.       PLANS

         If said deed refers to a plan necessary to be recorded therewith the
         SELLER shall deliver such plan with the deed in form adequate for
         recording or registration.

6.       REGISTERED TITLE

         In addition to the foregoing, if the title to said premises is
         registered, said deed shall be in form sufficient to entitle the BUYER
         to a Certificate of Title of said premises, and the SELLER shall
         deliver with said deed all instruments, if any, necessary to enable the
         BUYER to obtain such Certificate of Title.

7.       PURCHASE PRICE
         (fill in); space is allowed to write out the amounts if desired

         The agreed purchase price for said premises is Three Million, Two
         Hundred Thousand ($3,200,000.00) dollars, of which
         $   50,000.00     have been paid as a deposit prior hereto
         $  100,000.00     have been paid as a deposit this day and
         $
         $3,050,000.00     are to be paid at the time of delivery of the deed by
                           certified, cashier's, treasurer's or bankcheck(s)
                           drawn on Boston area banks and payable to Seller
                           without intervening endorsement other than that of
                           Buyer; or if Seller*
         $
         --------------------------
         $3,200,000.00     TOTAL

         *so requests, by wire transfer of immediately available federal funds
         **of Second Avenue made after said Plan
         ***and the lien for municipal betterments assessed prior to the date of
         this agreement in connection with the taking/layout of Second Avenue


<TABLE>
<S>                                                <C>
COPYRIGHT (C) 1979, 1984, 1986, 1 987, 1988, 1991  [LOGO]  All rights reserved. This form may not be copied or
        GREATER BOSTON REAL ESTATE BOARD                   reproduced in whole or in part in any manner whatever
                                                           without the prior express written consent of the Greater
                                                           Boston Real Estate Board.
</TABLE>

<PAGE>   2

8.       TIME FOR PERFORMANCE; DELIVERY OF DEED (fill in)

         Such deed is to be delivered at 10:00 o'clock A.M. on the 4th day of
         October, 1999, at the offices of Burns & Levinson LLP in Boston,
         Massachusetts unless otherwise agreed upon in writing. It is agreed
         that time is of the essence of this agreement.

9.       POSSESSION AND CONDITION OF PREMISE
         (attach a list of exceptions, if any)

         Full possession of said premises free of all tenants and occupants,
         except * , is to be delivered at the time of the delivery of the deed,
         said premises to be then (a) in the same condition as they now are,
         reasonable use and wear thereof excepted, and (b) not in violation of
         said building and zoning laws, and (c) in compliance with provisions of
         any instrument referred to in clause 4 hereof. The BUYER shall be
         entitled personally to inspect said premises prior to the delivery of
         the deed in order to determine whether the condition thereof complies
         with the terms of this clause.

         *those under the leases and tenancies referred to in clause 4(f) hereof

10.      EXTENSION TO PERFECT TITLE OR MAKE PREMISES CONFORM
         (Change period of time if desired).

         If the SELLER shall be unable to give title or to make conveyance, or
         to deliver possession of the premises, all as herein stipulated, or if
         at the time of the delivery of the deed the premises do not conform
         with the provisions hereof, then the SELLER shall use reasonable
         efforts to remove any defects in title, or to deliver possession as
         provided herein, or to make the said premises conform to the provisions
         hereof, as the case may be, in which event the time for performance
         hereof shall be extended for a period of thirty days. Provided,
         however, Seller shall not be obligated to expend more than $50,000.00
         (including attorneys' fees)**

11.      FAILURE TO PERFECT TITLE OR MAKE PREMISES CONFORM, etc.

         If at the expiration of the extended time the SELLER shall have failed
         so to remove any defects in title, deliver possession, or make the
         premises conform, as the case may be, all as herein agreed, or if at
         any time during the period of this agreement or any extension thereof,
         the holder of a mortgage on said premises shall refuse to permit the
         insurance proceeds, if any, to be used for such purposes, then any
         payments made under this agreement shall be forthwith refunded and all
         other obligations of the parties hereto shall cease and this agreement
         shall be void without recourse to the parties hereto.

12.      BUYER's ELECTION TO ACCEPT TITLE

         The BUYER shall have the election, at either the original or any
         extended time for performance, to accept such title as the SELLER can
         deliver to the said premises in their then condition and to pay
         therefore the purchase price without deduction, in which case the
         SELLER shall convey such title, except that in the event of such
         conveyance in accord with the provisions of this clause, if the said
         premises shall have been damaged by fire or casualty insured against,
         then the SELLER shall, unless the SELLER has previously restored the
         premises to their former condition, either
           (a) pay over or assign to the BUYER, on delivery of the deed, all
               amounts recovered or recoverable on account of such insurance,
               less any amounts reasonably expended by the SELLER for any
               partial restoration, or
           (b) if a holder of a mortgage on said premises shall not permit the
               insurance proceeds or a part thereof to be used to restore the
               said premises to their former condition or to be so paid over or
               assigned, give to the BUYER a credit against the purchase price,
               on delivery of the deed, equal to said amounts so recovered or
               recoverable and retained by the holder of the said mortgage less
               any amounts reasonably expended by the SELLER for any partial
               restoration.

13.      ACCEPTANCE OF DEED

         The acceptance of a deed by the BUYER or his nominee as the case may
         be, shall be deemed to be a full performance and discharge of every
         agreement and obligation herein contained or expressed, except such as
         are, by the terms hereof, to be performed after or to survive the
         delivery of said deed.

14.      USE OF MONEY TO CLEAR TITLE

         To enable the SELLER to make conveyance as herein provided, the SELLER
         may, at the time of delivery of the deed, use the purchase money or any
         portion thereof to clear the title of any or all encumbrances or
         interests, provided that all instruments so procured are recorded
         simultaneously with the delivery of said deed or, in the case of the
         existing mortgage on the premises, customary arrangements are made for
         the subsequent procuring and recording of ***

         Until the delivery of the deed, the SELLER shall maintain insurance on
         said premises as follows:
            Type of Insurance                      Amount of Coverage
         ***the discharge thereof
         (a) Fire and Extended Coverage         *$ As presently insured
         (b)

15.      INSURANCE
         *Insert amount (list additional types of insurance and amounts as
          agreed)

16.      ADJUSTMENTS
         (list operating expenses, if any, or attach schedule)

         Collected rents, water and sewer use charges****, and taxes for the
         then current fiscal year****, shall be apportioned, as of the day of
         performance of this agreement and the net amount thereof shall be added
         to or deducted from, as the case may be, the purchase price payable by
         the BUYER at the time of delivery of the deed. Uncollected rents for
         the current rental period shall be apportioned if and when collected by
         either party.

         **in exercising reasonable efforts hereunder, but such limit shall not
         apply to amounts necessary to pay real estate taxes due and to pay off
         any mortgage or other voluntary lien granted by Seller
         ****(to the extent not payable by tenants under the leases)


<PAGE>   3


17.      ADJUSTMENT OF UNASSESSED AND ABATED TAXES

         If the amount of said taxes is not known at the time of the delivery of
         the deed, they shall be apportioned on the basis of the taxes assessed
         for the preceding fiscal year, with a reapportionment as soon as the
         new tax rate and valuation can be ascertained; and, if the taxes which
         are to be apportioned shall thereafter be reduced by abatement, the
         amount of such abatement, less the reasonable cost of obtaining the
         same, shall be apportioned between the parties, provided that neither
         party shall be obligated to institute or prosecute proceedings for an
         abatement unless herein otherwise agreed.

18.      BROKER's FEE
         (fill in fee with dollar amount or percentage; also name of Brokerage
         firm(s))

         A Broker's fee for professional services of (i) $160,000 is due from
         the SELLER to Spaulding & Slye Collier International and (ii) of
         $64,000.00 is due from the Seller to Insignia ESG, Buyer's broker, if,
         as and when papers pass hereunder, the deed is recorded and Seller
         receives the full consideration, due hereunder and only in such event.

19.      BROKER(S) WARRANTY
         (fill in name)

         The Broker(s) named herein Spaulding & Slye Colliers International,
         and Insignia ESG warrant(s) that the Broker(s) is (are) duly licensed
         as such by the Commonwealth of Massachusetts.

20.      DEPOSIT
         (fill in name)

         All deposits made hereunder shall be held in escrow by Spaulding & Slye
         Colliers International as escrow agent subject to the terms of this
         agreement and shall be duly accounted for at the time for performance
         of this agreement. In the event of any disagreement between the
         parties, the escrow agent may retain all deposits made under this
         agreement pending instructions mutually given by the SELLER and the
         BUYER. ALL deposits shall be held in an interest bearing account and
         all interest shall be paid to Buyer at the time of closing unless
         Buyer*

21.      BUYER's DEFAULT; DAMAGES

         If the BUYER shall fail to fulfill the BUYER's agreements herein, all
         deposits made hereunder by the BUYER shall be retained by the SELLER as
         liquidated damages as Seller's sole and exclusive remedy both at law
         or in equity for any by default Buyer.

22.      RELEASE BY HUSBAND OR WIFE

         *defaults hereunder in which case such interest shall be paid to Seller

23.      BROKER AS PARTY

         The Broker(s) named herein join(s) in this agreement and become(s) a
         party hereto, insofar as any provisions of this agreement expressly
         apply to the Broker(s), and to any amendments or modifications of such
         provisions to which the Broker(s) agree(s) in writing.

24.      LIABILITY OF TRUSTEE, SHAREHOLDER, BENEFICIARY, etc.

         If the SELLER or BUYER executes this agreement in a representative or
         fiduciary capacity, only the principal or the estate represented shall
         be bound, and neither the SELLER or BUYER so executing, nor any
         shareholder or beneficiary of any trust, shall be personally liable for
         any obligation, express or implied, hereunder. The provisions of this
         Section 24 shall survive the closing and shall apply to this Agreement
         and shall also apply to and be deemed to*

25.      WARRANTIES AND REPRESENTATIONS
         (fill in); if none, state "none"; if any listed, indicate by whom each
         warranty or representation was made

         The BUYER acknowledges that the BUYER has not been influenced to enter
         into this transaction nor has he relied upon any warranties or
         representations not set forth in this agreement, except for the
         following additional warranties and representations, if any, made by
         either the SELLER or the Broker(s): NONE

         *be incorporated in and to apply to all documents now or hereafter
         executed by Seller in connection herewith and in connection with the
         transactions contemplated hereby.


<PAGE>   4


27.      CONSTRUCTION OF AGREEMENT

         This instrument, executed in multiple counterparts, is to be construed
         as a Massachusetts contract, is to take effect as a sealed instrument,
         sets forth the entire contract between the parties, is binding upon and
         enures to the benefit of the parties hereto and their respective heirs,
         devisees, executors, administrators, successors and assigns, and may be
         cancelled, modified or amended only by a written instrument executed by
         both the SELLER and the BUYER. If two or more persons are named herein
         as BUYER their obligations hereunder shall be joint and several. The
         captions and marginal notes are used only as a matter of convenience
         and are not to be considered a part of this agreement or to be used in
         determining the intent of the parties to it.

30.      ADDITIONAL PROVISIONS

         The rider attached hereto is incorporated herein by reference.


FOR RESIDENTIAL PROPERTY CONSTRUCTED PRIOR TO 1978, BUYER MUST ALSO HAVE SIGNED
            LEAD PAINT "PROPERTY TRANSFER NOTIFICATION CERTIFICATION"


NOTICE: This is a legal document that creates binding obligations. If not
        understood, consult an attorney.

  /s/ Barry L. Solar, Trustee           /s/ Robert L. Solar, Trustee
  ------------------------------------  ----------------------------------------
  SELLER (or spouse)                    SELLER

  /s/ Paul J. Mellett CFO
  ------------------------------------  ----------------------------------------
  BUYER                                 BUYER

         /s/ Alexander D. Dauria        /s/ Stephen J. Murphy
         ------------------------------------------------------------
                                    Broker(s}



- --------------------------------------------------------------------------------

                       EXTENSION OF TIME FOR PERFORMANCE
                                                               Date ____________

    The time for the performance of the foregoing agreement is extended until
______________________ o'clock __M. on the _____________ day of __________ 19__,
time still being of the essence of this agreement as extended. In all other
respects, this agreement is hereby ratified and confirmed.

    This extension, executed in multiple counterparts, is intended to take
effect as a sealed instrument.


  ------------------------------------  ----------------------------------------
  SELLER (or spouse)                    SELLER


  ------------------------------------  ----------------------------------------
  BUYER                                 BUYER


         ------------------------------------------------------------
                                    Broker(s}

- --------------------------------------------------------------------------------



<PAGE>   5

                      RIDER TO PURCHASE AND SALE AGREEMENT
                                 BY AND BETWEEN
                BARRY L. SOLAR AND ROBERT L. SOLAR, AS TRUSTEES
                   AND NOT INDIVIDUALLY, OF 211 SECOND AVENUE
              REALTY TRUST, u/d/t DATED MARCH 8, 1988, AS SELLERS,
                                      AND
                     GELTEX PHARMACEUTICALS, INC., AS BUYER

31.  REPRESENTATIONS AND WARRANTIES OF SELLER. Subject to all matters disclosed
     in any document delivered to Buyer by Seller prior to the expiration of the
     Due Diligence Period or on any Exhibit attached hereto, or other
     information disclosed in writing to Buyer by Seller after the date hereof
     and prior to the expiration of the Due Diligence Period and to all matters
     disclosed in any documents received by Buyer from anyone prior to the
     Closing and to all matters discovered by Buyer or as to which Buyer had
     knowledge at the time of Closing from any source or should have known based
     upon a physical inspection of the Premises for a transaction of this nature
     and amount and to all matters recorded and properly indexed at the
     Middlesex South District Registry of Deeds (all such matters being referred
     to herein as "Exception Matters"), Seller represents and warrants as
     follows:

     (a)  AUTHORITY. Seller is a trust duly formed and validly existing under
          the laws of the Commonwealth of Massachusetts and has all requisite
          power and authority to enter into this Agreement and the documents
          contemplated by Section 36, and to perform its obligations hereunder
          and thereunder. The execution and delivery of this Agreement and the
          documents contemplated by Section 36 have been duly authorized.

     (b)  NO CONFLICT. The execution and delivery of this Agreement and the
          consummation of the transactions contemplated hereunder on the part of
          Seller does not and will not conflict with or result in the breach of
          any terms or provisions of, or constitute a default under, or result
          in the creation or imposition of any lien, charge, or encumbrance upon
          any of the Premises or assets of the Seller by reason of the terms of
          any contract, mortgage, lien, lease, agreement, indenture, instrument
          or judgment to which Seller is a party or which is or purports to be
          binding upon Seller or which otherwise affects Seller or any of the
          Premises, which will not be discharged or released at or prior to
          Closing. No action by any federal, state or municipal or other
          governmental department, commission, board, bureau or instrumentality
          is necessary to make this Agreement a valid instrument binding upon
          Seller in accordance with its terms. The execution and delivery of
          this Agreement and the documents contemplated by Section 36 and the
          performance of the transactions contemplated hereby and thereby do not
          and will not contravene any provision of the declaration of trust of
          Seller, any judgment, order, decree, writ or injunction issued against
          Seller, or any provision of any law or governmental ordinances, rules,
          regulations, orders or requirements applicable to Seller, and do not
          require any consent or approval which has not yet been obtained.




                                       1
<PAGE>   6




     (c)  LEASES. There are no leases or occupancy agreements currently in
          effect which affect the Premises other than the two (2) leases
          referred to in Exhibit B, together with such additional leases
          approved or permitted pursuant to this Agreement or any tenancy at
          will agreement referred to in Section 4(F) (collectively, the
          "Leases"). The Leases are in full force and effect, without to
          Seller's knowledge, any default by Seller or any tenant, nor, to
          Seller's knowledge, are there any defenses, counterclaims, or offsets.
          Seller has not given or received any notice of default or any claim
          which remains uncured or unsatisfied, with respect to any of the
          Leases, and to the best of Seller's knowledge, there is no basis for
          any such claim or notice of default by any tenant. No leasing,
          brokerage or like commissions, fees and payments are due from Seller
          in respect of the Leases. None of the tenants has paid more than one
          month's rent in advance except for security deposits. All tenant
          improvements or work to be done, furnished or paid for by Seller, or
          credited or allowed to a tenant, for, or in connection with, the
          Premises pursuant to the Leases have been completed and paid for. The
          information regarding the Leases contained in Exhibit C is true,
          accurate and complete as of the date hereof.

     (d)  NO CONDEMNATION. Seller has not received any written notice of any
          pending and, to Seller's knowledge, there is no contemplated
          condemnation, eminent domain, or similar proceeding with respect to
          all or any portion of the Premises. The foregoing does not apply to
          takings already made.

     (e)  CONTRACTS. There are no construction, management, leasing, service,
          equipment, supply, maintenance or concession agreements in effect with
          respect to the Premises which would be binding on Buyer to which
          Seller is a party.

     (f)  COMPLIANCE. Seller has not received written notice of any existing
          violations of any federal, state, county or municipal laws,
          ordinances, orders, codes, regulations or requirements affecting the
          Premises which have not been cured.

     (g)  LITIGATION. There is no action, suit or proceeding pending against
          Seller, or, to Seller's knowledge, any action, suit or proceeding
          pending or threatened against or affecting the Premises.

     (h)  ENVIRONMENTAL MATTERS. Except as set forth below and in any
          environmental assessment or report delivered to Buyer, (i) neither
          Seller nor, to Seller's knowledge, any third party has engaged in the
          generation, use, manufacture, treatment, storage or disposal of or has
          released, any Hazardous Wastes or Hazardous Substances at, from, on,
          under or to the Premises in violation of law, and (ii) neither Seller
          nor, to Seller's knowledge, any third party has received any written
          notice from any governmental authority having jurisdiction over the
          Premises of any violation of any environmental law, regulation or
          ordinance with respect to the Premises. Notwithstanding the foregoing,
          Seller has informed Buyer that (i) tenant, LPL Alexandria, Inc., uses
          film processing and


                                       2
<PAGE>   7


          developing chemicals, (ii) tenant, Evergreen Solar, Inc., manufactures
          solar panels, and (iii) numerous prior tenants of the Premises may
          have used hazardous substances in connection with their business; and
          the acts of the present and prior tenants are excepted from the
          foregoing warranties. As used in this Agreement, the terms "HAZARDOUS
          SUBSTANCES" and "HAZARDOUS WASTES" shall have the meanings set forth
          in the Comprehensive Environmental Response, Compensation and
          Liability Act, as amended, and the regulations thereunder, the
          Resource Conservation and Recovery Act, as amended, and the
          regulations thereunder, and the Federal Clean Water Act, as amended,
          and the regulations thereunder, and such terms shall also include
          asbestos, petroleum products, radioactive materials and any regulated
          substances under any Federal, State or local environmental law,
          regulation or ordinance.

     (i)  FIRPTA. Seller is not a "foreign person" as defined in Section
          1445(F)(3) of the Internal Revenue Code.

32.  LIMITATIONS REGARDING REPRESENTATIONS AND WARRANTIES.

     (a)  Seller shall have no liability whatsoever to Buyer with respect to any
          Exception Matters.

     (b)  As used in this Agreement, the phrase "to Seller's knowledge", or
          words of similar import, shall mean the actual (and not constructive
          or imputed) knowledge, without independent investigation or inquiry,
          of Robert L. Solar, Richard L. Solar and Barry L. Solar. Seller
          represents that Robert L. Solar, Richard L. Solar and Barry L. Solar
          are the individuals with primary responsibility for the sale of the
          Property and Robert L. Solar is the individual with primary
          responsibility for overseeing the management and operation of the
          Property.

     (c)  Buyer represents that, as of the date hereof, it has no actual
          knowledge of any breach of any of Seller's representations and
          warranties.

33.  CONDITIONS PRECEDENT TO BUYER'S OBLIGATIONS. All of Buyer's obligations
     hereunder are expressly conditioned on the satisfaction at or before the
     time of Closing hereunder, or at or before such earlier time as may be
     expressly stated below, of each of the following conditions (any one or
     more of which may be waived in writing in whole or in part by Buyer, at
     Buyer's option):

     (a)  ACCURACY OF REPRESENTATIONS. All of the representations and warranties
          of Seller contained in this Agreement shall have been true and correct
          in all material respects when made, and shall be true and correct in
          all material respects on the date of Closing with the same effect as
          if made on and as of such date. If Seller notifies Buyer prior to the
          Closing that any of said representations and warranties are no longer
          true in all material respects, the Buyer shall have the right to
          terminate this Agreement by notice in writing to Seller, given no
          later




                                       3
<PAGE>   8



          than the first to occur of (i) the Closing or (ii) three (3) business
          days after such notice is given, in which event all deposits and all
          interest earned thereon shall be returned to Buyer. If Buyer does not
          so elect to terminate, then such representations and warranties shall
          be void and of no further force or effect and Seller shall have no
          liability whatsoever to Buyer with respect thereto.

     (b)  PERFORMANCE. Seller shall have performed, observed and complied with
          all covenants, agreements and conditions required by this Agreement to
          be performed, observed and complied with on its part prior to or as of
          Closing hereunder.

     (c)  DOCUMENTS AND DELIVERIES.

          (i)  All instruments and documents required on Seller's part to
               effectuate this Agreement and the transactions contemplated
               hereby shall be delivered to Buyer and shall be in form and
               substance consistent with the requirements herein.

          (ii) Seller represents that Seller has delivered to Buyer prior to or
               simultaneously with the execution of this Agreement (and Buyer
               acknowledges receipt of same) the following materials: (i) a copy
               of Seller's title insurance policy; (ii) all environmental
               studies and reports regarding the Premises that have been
               produced for Seller or are in Seller's possession; (iii) any
               survey of the Premises that has been produced for Seller or is in
               Seller's possession; and (iv) true and complete copies of the
               current leases, or other agreements granting occupancy rights to
               any person or entity. The materials referred to in this
               subsection 33(c)(ii) consist of the following:

               -    Stewart Title Insurance Policy No. O-9941-08861

               -    Haley & Aldrich Report dated March 1998 entitled "Release
                    Notification and Downgradient Property Status Opinion 200
                    West Street, Waltham, Massachusetts"

               -    Goldberg-Zoino & Associates, Inc. report dated March, 1988
                    entitled "Environmental Site Assessment, 211 Second Avenue,
                    Waltham, Massachusetts"

               -    Notification to Abutters under the Massachusetts Wetlands
                    Protection Act sent by Geltex with respect to 153 Second
                    Avenue

               -    Survey dated April 21, 1988 prepared by Vanasse Hangen
                    Brustlin, Inc.

               -    Lease dated June 1, 1994 to LPL Alexandria, Inc., with
                    Addenda and Addendum 2, and renewal notification dated June
                    10, 1999

               -    Lease dated September 15, 1995 to Evergreen Solar, Inc. with
                    Renewal Agreement dated July __, 1999.



                                       4
<PAGE>   9


34.  DUE DILIGENCE PERIOD; ACCESS; PURCHASE "AS IS".

     (a)  During the Due Diligence Period, Buyer, its agents, representatives,
          architects and lenders shall be entitled to enter upon the Premises
          from time to time (such entry to be in the presence of Seller or
          Seller's agent and during regular business hours), including all
          leased areas, upon twenty-four (24) hours prior notice to Seller, to
          perform inspections and tests of the Premises, including surveys,
          environmental studies, examinations and tests of all structural and
          mechanical systems within the building, to examine the books and
          records of Seller relating to the Premises, and to communicate
          directly with the tenants at the Premises. After the Due Diligence
          Period, buyer, its agents, representatives, architects and lenders
          shall be entitled to enter upon the Premises from time to time (such
          entry to be in the presence of Seller or Seller's agent, and during
          regular business hours), including all leased areas, upon twenty-four
          (24) hours prior notice to Seller, for the purpose of preparing
          architectural designs and satisfying the requirements of Buyer's
          lender. Before entering upon the Premises, Buyer shall furnish to
          Seller evidence of general comprehensive and contractual liability
          insurance coverage of at least $2,000,000.00 and insuring against such
          risks as Seller may reasonably require. Such insurance shall name
          Seller as an additional insured. Notwithstanding the foregoing, Buyer
          shall not be permitted to unreasonably interfere with Seller's
          operations at the Premises or interfere with the tenants' operations
          at the Premises, and the scheduling of any inspections shall take into
          account the timing and availability of access to the tenants'
          Premises, pursuant to the tenants' rights under the Leases or
          otherwise. If Buyer wishes to engage in any testing or sampling of
          surface or subsurface soils, surface water, groundwater or any
          materials in or about the building in connection with Buyer's
          environmental due diligence, such testing or sampling shall be subject
          to Seller's prior approval (which approval shall not be unreasonably
          withheld) of a protocol for such testing or sampling which protocol
          shall detail the nature, timing, location and extent of such testing
          and sampling and the means and methods to be utilized. Buyer shall
          promptly repair at Buyer's sole cost and expense, any damage to the
          Premises caused by any such tests or investigations, shall indemnify
          and defend Seller from any and all loss, cost, liabilities, claims,
          and expenses whatsoever (including reasonable attorneys' fees of
          counsel selected by Seller) arising out of any damage to persons or
          property occurring in or about the Premises and caused in any way from
          the inspection permitted hereby, and shall promptly return the
          Premises to the same condition as it was in prior to the inspection.
          The foregoing indemnification shall survive Closing or the termination
          of this Agreement, notwithstanding any other provision of this
          Agreement.

     (b)  The term "Due Diligence Period", as used herein, shall mean the period
          ending at 5:00 p.m. on the date sixty (60) days after the date hereof.
          Buyer may, in its sole discretion, terminate this Agreement by giving
          written notice of such election to Seller on any day prior to and
          including the final day of the Due




                                       5
<PAGE>   10


          Diligence Period, in which event the Deposit, together with any
          interest earned thereon, shall be returned forthwith to Buyer and,
          except as expressly set forth herein, neither party shall have any
          further liability or obligation to the other hereunder. In the absence
          of such written notice, the contingency provided for in this Section
          34(b) no longer shall be applicable, and this Agreement shall continue
          in full force and effect.

     (c)  Buyer acknowledges and agrees that Buyer is acquiring the Premises in
          its "AS IS" condition, WITH ALL FAULTS, IF ANY, AND EXCEPT AS PROVIDED
          IN SECTION 31 HEREOF, WITHOUT ANY WARRANTY, EXPRESS OR IMPLIED. Other
          than as expressly set forth herein, neither Seller nor any agents,
          representative, or employees of Seller have made any representations
          or warranties, direct or indirect, oral or written, express or
          implied, to Buyer or any agents, representatives, or employees of
          Buyer with respect to the condition of the Premises, its fitness for
          any particular purpose, or its compliance with any laws or any other
          matter or thing affecting or related to the Premises, and Buyer is not
          aware of and does not rely upon any such representation. Buyer
          acknowledges that the Due Diligence Period will have afforded Buyer
          the opportunity to make such inspections (or have such inspections
          made by consultants) as it desires of the Premises and all factors
          relevant to its use, including, without limitation, the interior,
          exterior, and structure of all improvements, and the condition of
          soils and subsurfaces. Except as otherwise expressly set forth in any
          representation or warranty made by Seller in Section 31 of this
          Agreement, any information, documents or materials which have been or
          hereafter are made available to Buyer are made available solely as an
          accommodation to Buyer in the conduct of its due diligence, and Seller
          makes no representation or warranty as to the accuracy thereof. The
          provisions of this Section 34(c) shall survive Closing.

     (d)  If Buyer does not give notice to Seller terminating this Agreement
          within the time set forth above, the title to the Premises shall,
          except as to title matters occurring after the date of this Agreement,
          be conclusively deemed to comply with the requirements of Paragraph 4
          of this Agreement and, except as to matters occurring after the date
          of the Agreement, the condition of the Premises shall conclusively be
          deemed to comply with the requirements of paragraph 9 of this
          Agreement

35.  TERMINATION FOR DEFAULT. Notwithstanding anything in this Agreement to the
     contrary, Seller may cancel or terminate any of the Leases or commence
     collection, or other remedial action against any tenant without Buyer's
     consent upon the occurrence of any default by the tenant under said Lease,
     provided that Seller shall give written notice to Buyer of the same.

36.  SELLER DELIVERIES. At Closing, Seller shall deliver to Buyer the following,
     and it shall be a condition to Buyer's obligation to close that Seller
     shall have delivered the same to Buyer:



                                       6
<PAGE>   11


     (a)  A Massachusetts Quitclaim Deed ("Deed") to the Premises from Seller,
          duly executed and acknowledged by Seller.

     (b)  An Assignment and Assumption of Interest in Leases from Seller, duly
          executed by Seller.

     (c)  Originals or, if originals are not available, copies certified by
          Seller of the Leases.

     (d)  A notice to each tenant, executed by Seller, advising of the sale of
          the Premises and directing that rent and other payments thereafter be
          sent to Buyer at the address provided by Buyer at Closing.

     (e)  Such affidavits or letters of indemnity as the Buyer's title insurer
          shall reasonably require in order to issue, without extra charge, an
          owner's policy of title insurance free of any exceptions for unfiled
          mechanics' or materialmen's liens for work performed by Seller prior
          to Closing, or for rights of parties in possession other than pursuant
          to the Leases.

     (f)  A Non-Foreign Affidavit as required by the Foreign Investors in Real
          Property Tax Act ("FIRPTA"), duly executed by Seller.

     (g)  A certification by Seller that all representations and warranties made
          by Seller in Section 31 of this Agreement are true and correct in all
          material respects on the date of Closing, except as may be set forth
          in said certificate with respect to matters since the date hereof.
          Seller acknowledges and Buyer agrees that if said certificate does not
          satisfy Section 33(a) hereof, Buyer shall have the right to terminate
          this Agreement as its sole remedy and receive the Deposit and all
          interest accrued thereon.

     (h)  A Certificate of the Trustees of Seller and a Direction of the Sole
          Beneficiary of Seller evidencing approval of and authorization to
          execute this Agreement and the closing documents, and to consummate
          the transactions contemplated hereby.

     (i)  A Certificate of Legal Existence and Good standing for the limited
          partnership which is the sole Beneficiary of Seller.

     (j)  All other instruments and documents reasonably required to effectuate
          this agreement and the transactions contemplated hereby, including,
          without limitation, a closing statement describing the sources and
          uses of funds in connection with the Closing.



                                       7
<PAGE>   12


37.  BUYER DELIVERIES. At Closing, Buyer shall deliver to Seller the following
     and it shall be a condition to Seller's obligation to close that Buyer
     shall have delivered the same to Seller:

     (a)  A certification by Buyer that all representations and warranties made
          by Buyer in Section 40 of this Agreement are true and correct in all
          material respects on the date of Closing.

     (b)  The Assignment and Assumption of Interest in Leases referred to in
          Section 36(b) duly executed and acknowledged by Buyer.

     (c)  Duly certified resolutions from the Board of Directors of Buyer
          evidencing approval of and authorization to execute this Agreement and
          the closing documents, and to consummate the transactions contemplated
          hereby.

     (d)  A Certificate of Legal Existence for Buyer.

     (e)  All other instruments and documents reasonably required to effectuate
          this Agreement and the transactions contemplated hereby, including,
          without limitation, a closing statement describing the sources and
          uses of funds in connection with the Closing.

38.  NOTICES. All notices and other communications provided for herein shall be
     in writing and shall be sent to the address set forth below (or such other
     address as a party may hereafter designate for itself by notice to the
     other parties as required hereby) of the party for whom such notice or
     communication is intended:

                  If to Seller:     211 Second Avenue Realty Trust
                                    c/o Walcott Corporation
                                    1050 Commonwealth Avenue
                                    Boston, MA 02215

                  With a copy to:   Barry L. Solar, Esquire
                                    Bums & Levinson, LLP
                                    125 Summer Street
                                    Boston, MA 02110-1624

                  If to Buyer:      Mr. Paul Mellett
                                    Chief Financial Officer
                                    Geltex Pharmaceuticals, Inc.
                                    9 Fourth Avenue
                                    Waltham, MA 02154-7506



                                       8

<PAGE>   13

                  With a copy to:   Kathryn Cochrane Murphy, Esquire
                                    Palmer & Dodge
                                    One Beacon Street
                                    Boston, Massachusetts 02108

     Any such notice or communication shall be sufficient if sent by registered
     or certified mail, return receipt requested, postage prepaid; by hand
     delivery; by overnight courier service; or by telecopy, with an original by
     regular mail. Any such notice or communication shall be effective when
     delivered or when delivery is refused.

39.  BROKER'S REPRESENTATION. Each party warrants and represents to the other
     that such party has not dealt with any real estate broker in connection
     with this transaction or the Premises other than the brokers named in
     Paragraph 18 hereof, and each party agrees and does hereby indemnify and
     hold the other harmless from any liability or loss suffered or incurred by
     the other (including, without limitation, reasonable attorney's fees and
     court costs) arising out of a breach of this warranty and representation.
     Seller shall be responsible for any and all commissions and fees due to
     Spaulding & Slye Colliers International and for the commission of
     $64,000.00 due to Insignia ESG as set forth in Paragraph 18. Buyer shall be
     responsible for any other commissions and fees due to Insignia ESG. The
     provisions of this Paragraph shall survive delivery of the deed hereunder.

40.  REPRESENTATIONS OF BUYER.

     (a)  AUTHORITY. Buyer is a corporation, duly organized, validly existing
          and in good standing under the laws of Delaware and has all requisite
          power and authority to enter into this Agreement and to perform its
          obligations hereunder. The execution and delivery of this Agreement by
          Buyer has been duly authorized.

     (b)  NO CONFLICT. The execution and delivery of this Agreement and the
          consummation of the transactions contemplated hereunder on the part of
          Buyer does not and will not violate any applicable law, ordinance,
          statute, rule, regulation, order, decree or judgment, conflict with or
          result in the breach of any material terms or provisions of, or
          constitute a default under, or result in the creation or imposition of
          any lien, charge, or encumbrance upon any of the property or assets of
          the Buyer by reason of the terms of any contract, mortgage, lien,
          lease, agreement, indenture, instrument or judgment to which the Buyer
          is a party or which is or purports to be binding upon Buyer or which
          otherwise affects Buyer. No action by any federal, state, or municipal
          or other governmental department, commission, board, bureau or
          instrumentality is necessary to make this Agreement a valid instrument
          binding upon Buyer in accordance with its terms.



                                       9
<PAGE>   14


41.  RECORDING. This Agreement or any notice or memorandum hereof shall not be
     recorded in any public record. A violation of this prohibition shall
     constitute a material breach of Buyer, entitling Seller to terminate this
     Agreement.

42.  SURVIVAL. Unless otherwise expressly stated in this Agreement, each of the
     warranties and representations of Seller and Buyer shall survive the
     Closing and delivery of the Deed and other closing documents by Seller to
     Buyer, and shall not be deemed to have merged therewith; provided, however,
     that any suit or action for breach of any of the representations or
     warranties set forth herein must be commenced within six (6) months after
     the Closing, or any claim based thereon shall be deemed irrevocably waived.

     IN WITNESS WHEREOF, the parties have executed and delivered this Agreement
as of the date first above written.


                           SELLER:

                                    /s/ Barry L. Solar
                                    --------------------------------------------
                                    Barry L. Solar, as Trustee and not
                                    Individually, of 211 Second Avenue
                                    Realty Trust


                                    /s/ Robert L. Solar, Trustee
                                    --------------------------------------------
                                    Robert L. Solar, as Trustee and not
                                    Individually, of 211 Second Avenue
                                    Realty Trust


                           BUYER:

                                    GELTEX PHARMACEUTICALS, INC.


                                    By: /s/ Paul J. Mellett Jr.
                                        ----------------------------------------
                                    Name: Paul J. Mellett Jr.
                                          --------------------------------------
                                    Title: Chief Financial Officer
                                           -------------------------------------


                                       10
<PAGE>   15


                                   EXHIBIT B


1.      Lease dated September 15, 1995 to Evergreen Solar, Inc. as affected
        Addenda #1 dated September 15, 1995 by renewal agreement dated July __,
        1998;

2.      Lease dated June 1, 1994 to LPL Alexandria, Inc. (including Addenda and
        Addendum 2 as affected by letter dated June 10, 1999 from Lerner
        Processing Labs, Inc. exercising the option to renew contained in said
        lease and as further affected by letters from 211 Second Avenue Realty
        L.P. to Lerner Processing Labs dated respectively February 20, 1995,
        April 16, 1996 and March 29, 1999.



                                       1


<PAGE>   16

                                   Exhibit C


EVERGREEN SOLAR, INC.


Lease signing page         Dated September 14, 1995   Signed and dated

Renewal Agreement:         Dated July, 1998           Signed and dated

Actual rent being paid:    $11,750.00/mo.

Date July rent paid:       July 6, 1999

Expiration:                September 30, 1999

Security Deposit:          $5,875.00



LERNER PROCESSING LABS

Actual rent being paid:    $6,533.33

Date July rent paid:       June 28, 1999

Expiration:                March 31, 2005

Security Deposit:          $5,390.00




                                       1
<PAGE>   17


Amounts paid to Carl Cincotta Landscaping during 1998 for snow removal and
landscaping, January 1, 1998 through December 31, 1998.

Tenants were billed their share, plus 15% to cover cost of overhead.

         Evergreen Solar, Inc.               49%

         Lerner Processing Labs              51%

         Amount billed by Carl Cincotta:               $4,345.00



                                       2

<PAGE>   18





                          211 SECOND AVENUE REALTY LP
                               VENDOR QUICKREPORT
                         JANUARY THROUGH DECEMBER 1998


         TYPE                DATE             NUM              AMOUNT
- -----------------------    -------           ----            ---------

Carl J. Cincotta
   Check                   1/14/98           1685              -200.00
   Check                    2/5/98           1688              -840.00
   Check                    3/3/98           1670              -150.00
   Check                    4/3/98           1673              -200.00
   Check                    5/5/98           1678            -1,135.00
   Check                    6/5/98           1681              -150.00
   Check                    7/7/98           1684              -530.00
   Check                   7/30/98           1687              -200.00
   Check                   9/10/98           1691              -245.00
   Check                   10/5/98           1695              -250.00
   Check                   11/9/98           1697               -95.00
   Check                   12/2/98           1700              -200.00
   Check                  12/15/98           1706              -150.00






                                       3



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