<PAGE>
PROSPECTUS SUPPLEMENT
(TO PROSPECTUS DATED APRIL 27, 2000)
MILLENNIUM PHARMACEUTICALS, INC.
$400,000,000 Principal Amount 5.50% Convertible Subordinated Notes
Due January 15, 2007
4,753,920 Shares of Common Stock issuable upon conversion of the Notes
211,554 Shares of Common Stock issuable upon exercise of
outstanding warrants to purchase common stock
--------------------------
This prospectus supplement relates to resales by selling holders of:
- our 5.50% Convertible Subordinated Notes due January 15, 2007;
- our common stock into which the notes are convertible; and
- our common stock issuable upon exercise of warrants to purchase our
common stock held by GATX Capital Corporation and MM Ventures
This prospectus supplement should be read in conjunction with the
prospectus dated April 27, 2000, which is to be delivered with this prospectus
supplement.
SEE "RISK FACTORS" BEGINNING ON PAGE 6 OF THE PROSPECTUS TO READ ABOUT
FACTORS YOU SHOULD CONSIDER BEFORE BUYING THE NOTES OR OUR COMMON STOCK.
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Neither the Securities and Exchange Commission nor any other regulatory
body has approved or disapproved of these securities or passed upon the accuracy
or adequacy of this prospectus. Any representation to the contrary is a criminal
offense.
---------------------
The information in the table appearing in the prospectus under the
heading "Selling Holders" is superseded in part by the information appearing in
the following table:
<TABLE>
<CAPTION>
Number of
Notes Percentage Shares of
Notes Beneficially of the Common Number of Number of Percentage
Beneficially Owned Notes Stock Shares of Shares of of Shares of
Owned Notes After Beneficially Beneficially Common Common Stock Common Stock
Prior to Offered Offering Owned Owned Stock Beneficially Beneficially
Selling Offering Hereby (1) After the Prior to Offered Owned After Owned After
Securityholder (in $1,000) (in $1,000) (in $1,000) Offering Offering Hereby Offering(1) Offering(1)
<S> <C> <C> <C> <C> <C> <C> <C> <C>
Amoco Corp. 656 656 0 0 7,796 7,796 0 0
Master Trust
Arkansas 2,132 2,132 0 0 25,338 25,338 0 0
Teachers
Retirement
System
</TABLE>
<PAGE>
<TABLE>
<CAPTION>
Number of
Notes Percentage Shares of
Notes Beneficially of the Common Number of Number of Percentage
Beneficially Owned Notes Stock Shares of Shares of of Shares of
Owned Notes After Beneficially Beneficially Common Common Stock Common Stock
Prior to Offered Offering Owned Owned Stock Beneficially Beneficially
Selling Offering Hereby (1) After the Prior to Offered Owned After Owned After
Securityholder (in $1,000) (in $1,000) (in $1,000) Offering Offering Hereby Offering(1) Offering(1)
<S> <C> <C> <C> <C> <C> <C> <C> <C>
Associated 450 450 0 0 5,348 5,348 0 0
Electric & Gas
Insurance
Services Limited
Baptist Health 103 103 0 0 1,224 1,224 0 0
of South Florida
Boston Museum 83 83 0 0 986 986 0 0
of Fine Arts
Champion 393 393 0 0 4,670 4,670 0 0
International
Corp.
City University 87 87 0 0 1,033 1,033 0 0
of New York
Credit Suisse 2,818 2,818 0 0 33,491 33,491 0 0
First Boston
Corporation
David Lipscomb 105 105 0 0 1,247 1,247 0 0
University
General
Endowment
Deephaven 10,886 10,886 0 0 129,377 129,377 0 0
Domestic
Convertible
Trading Ltd
Donaldson, 575 575 0 0 6,833 6,833 0 0
Lufkin &
Jenrette
Securities Corp.
Engineers Joint 289 289 0 0 3,434 3,434 0 0
Pension Fund
EQAT Alliance 2,955 2,955 0 0 35,119 35,119 0 0
Growth & Income
Equitable Life 1,925 1,925 0 0 22,878 22,878 0 0
Assurance
Separate
Account -
Convertible
</TABLE>
2
<PAGE>
<TABLE>
<CAPTION>
Number of
Notes Percentage Shares of
Notes Beneficially of the Common Number of Number of Percentage
Beneficially Owned Notes Stock Shares of Shares of of Shares of
Owned Notes After Beneficially Beneficially Common Common Stock Common Stock
Prior to Offered Offering Owned Owned Stock Beneficially Beneficially
Selling Offering Hereby (1) After the Prior to Offered Owned After Owned After
Securityholder (in $1,000) (in $1,000) (in $1,000) Offering Offering Hereby Offering(1) Offering(1)
<S> <C> <C> <C> <C> <C> <C> <C> <C>
EQAT Alliance 1,605 1,605 0 0 19,075 19,075 0 0
Growth Investors
Fidelity 8,250 8,250 0 0 98,049 98,049
Financial
Trust: Fidelity
Convertible &
Securities Fund
Forest 109 109 0 0 1,295 1,295 0 0
Alternative
Strategies Fund
II LP A5M
Forest Fulcrum 900 900 0 0 10,696 10,696 0 0
Fund LP
Forest Global 6,625 6,625 0 0 78,736 78,736 0 0
Convertible
Fund A-5
Goldman Sachs 2,176 2,176 0 0 25,861 25,861 0 0
and Company
Grady Hospital 136 136 0 0 1,616 1,616 0 0
HBK Master Fund 2,500 2,500 0 0 29,712 29,712 0 0
L.P.
Jeffries & Co. 656 656 0 0 7,796 7,796 0 0
Inc.
JAS Securities 1,500 1,500 0 0 17,827 17,827 0 0
J.P. Morgan 6,925 6,925 0 0 82,302 82,302 0 0
Securities Inc.
KBC Financial 2,000 2,000 0 0 23,769 23,769 0 0
Products
Key Asset 350 350 0 0 4,159 4,159 0 0
Management,
Inc., as Agent
for the Victory
Convertible
Securities Fund
Local 56 56 0 0 665 665 0 0
Initiatives
Support
Corporation
</TABLE>
3
<PAGE>
<TABLE>
<CAPTION>
Number of
Notes Percentage Shares of
Notes Beneficially of the Common Number of Number of Percentage
Beneficially Owned Notes Stock Shares of Shares of of Shares of
Owned Notes After Beneficially Beneficially Common Common Stock Common Stock
Prior to Offered Offering Owned Owned Stock Beneficially Beneficially
Selling Offering Hereby (1) After the Prior to Offered Owned After Owned After
Securityholder (in $1,000) (in $1,000) (in $1,000) Offering Offering Hereby Offering(1) Offering(1)
<S> <C> <C> <C> <C> <C> <C> <C> <C>
Lord Abbett 7,600 7,600 0 0 90,324 90,324 0 0
Bond Debenture
Fund
Lyxor Master 1,000 1,000 0 0 11,884 11,884 0 0
Fund c/o Forest
Investment
Management LLC
Maryland State 3,397 3,397 0 0 40,372 40,372 0 0
Retirement
System
New Orleans 139 139 0 0 1,651 1,651 0 0
Firefighters
Nicholas-Applegate 738 738 0 0 8,770 8,770 0 0
Convertible Fund
Occidental 240 240 0 0 2,852 2,852 0 0
Petroleum
Physicians Life 226 226 0 0 2,685 2,685 0 0
Robertson 8,000 8,000 0 0 95,078 95,078 0 0
Stephens
Pilgrim 2,765 2,765 0 0 32,861 32,861 0 0
Convertible Fund
S G Cowen 7,000 7,000 0 0 83,193 83,193 0 0
Securities Corp.
Sagamore Hill 6,250 6,250 0 0 74,280 74,280 0 0
Hub Fund Ltd.
San Diego City 580 580 0 0 6,893 6,893 0 0
Retirement
San Diego 1,408 1,408 0 0 16,733 16,733 0 0
County
Convertible
Shell Pension 376 376 0 0 4,468 4,468 0 0
Trust
</TABLE>
4
<PAGE>
<TABLE>
<CAPTION>
Number of
Notes Percentage Shares of
Notes Beneficially of the Common Number of Number of Percentage
Beneficially Owned Notes Stock Shares of Shares of of Shares of
Owned Notes After Beneficially Beneficially Common Common Stock Common Stock
Prior to Offered Offering Owned Owned Stock Beneficially Beneficially
Selling Offering Hereby (1) After the Prior to Offered Owned After Owned After
Securityholder (in $1,000) (in $1,000) (in $1,000) Offering Offering Hereby Offering(1) Offering(1)
<S> <C> <C> <C> <C> <C> <C> <C> <C>
The Frist 285 285 0 0 3,387 3,387 0 0
Foundation
Tribeca 29,000 24,000 0 0 344,659 285,235 0 0
Investments LLC
Wake Forest 692 692 0 0 8,224 8,224 0 0
University
Writers 179 179 0 0 2,127 2,127 0 0
Guild-Industry
Health Fund
</TABLE>
(1) We do not know if, when or in what amounts a selling securityholder
may offer securities for sale and we do not know that the selling
securityholders will sell any or all of the securities offered hereby. Because
the selling securityholders may offer all or some of the securities pursuant to
this prospectus, and because there are currently no other agreements,
arrangements or understandings with respect to the sale of any of the securities
that will be held by the selling securityholders, no estimate can be given as to
the amount of the securities that will be held by the selling securityholders
after completion of the offering made by this prospectus. However, for purposes
of this table, we have assumed that, after completion of the offering, no
securities will be held by the selling securityholders.
The date of this prospectus supplement is July 19, 2000.
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