MILLENNIUM PHARMACEUTICALS INC
10-Q, EX-3.1, 2000-11-09
PHARMACEUTICAL PREPARATIONS
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                                                                     EXHIBIT 3.1



                        MILLENNIUM PHARMACEUTICALS, INC.
                            AMENDMENT TO THE BY-LAWS

         The Company's By-laws be and hereby are amended by adding the following
Article 5.10:


           5.10 EXECUTION OF PAPERS. Except as the directors may generally or in
particular cases authorize the execution thereof in some other manner, all
deeds, leases, transfers, contracts, bonds, notes, checks, drafts and other
obligations made, accepted or endorsed by the corporation shall be signed by the
president or by one of the vice presidents or by the treasurer.


                      Adopted by the Board of Directors as of September 28, 2000



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