GLOBAL PHARMACEUTICAL CORP \DE\
10KSB, 1999-03-26
PHARMACEUTICAL PREPARATIONS
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                     U.S. Securities and Exchange Commission
                             Washington, D.C. 20549
                                   Form 10-KSB

              [ X ] ANNUAL REPORT UNDER SECTION 13 OR 15(d) OF THE
                 SECURITIES EXCHANGE ACT OF 1934 [Fee Required]
                   For the fiscal year ended December 31, 1998
 
             [  ] TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE
                SECURITIES EXCHANGE ACT OF 1934 [No Fee Required]
            For the transition period from ___________ to ___________

                       Commission file number 33-99310-NY

                        Global Pharmaceutical Corporation
                 ----------------------------------------------
                 (Name of Small Business Issuer in its Charter)

                    Delaware                                 65-0403311 
         -------------------------------------------------------------------  
         (State or Other Jurisdiction of                  (I.R.S. Employer
          Incorporation or Organization)                 Identification No.)

             Castor & Kensington Aves., Philadelphia, PA        19124-5694
             -------------------------------------------------------------
               (Address of Principal Executive Offices)         (Zip Code)

                                 (215) 289-2220
                ------------------------------------------------
                (Issuer's Telephone Number, Including Area Code)

         Securities registered under Section 12(b) of the Exchange Act:

        Title of Each Class           Name of Each Exchange on Which Registered
               None                                     None           
        -------------------           -----------------------------------------

         Securities registered under Section 12(g) of the Exchange Act:

                     Common Stock, $.01 par value per share
         --------------------------------------------------------------
                                (Title of class)

         Check whether the issuer (1) filed all reports required to be filed by
Section 13 or 15(d) of the Exchange Act during the past 12 months (or for such
shorter period that the registrant was required to file such reports), and (2)
has been subject to such filing requirements for the past 90 days. Yes _X_  No__

         Check if there is no disclosure of delinquent filers in response to
Item 405 of Regulation S-B contained in this form, and no disclosure will be
contained, to the best of registrant's knowledge, in definitive proxy or
information statements incorporated by reference in part III of this Form 10-KSB
or any amendment to this Form 10-KSB. [X]

         State issuer's revenues for its most recent fiscal year $4,401,000

         The aggregate market value of voting stock held by non-affiliates of
the registrant as of March 9, 1999 (based on the closing price for such shares
on March 9, 1999 as reported by NASDAQ and the assumption for this computation
only that all directors and executive officers of the registrant are affiliates)
was $16,924,890.

         As of March 9, 1999, the number of shares outstanding of each of the
issuer's classes of common equity was 7,254,053 shares of common stock, $.01 par
value per share.

         Transitional Small Business Disclosure Format (check one) Yes__  No _X_

         Registrant's Proxy Statement to be filed with the Securities and
Exchange Commission in connection with solicitations of proxies for Registrant's
1999 Annual Meeting of Stockholders scheduled to be held on May 12, 1999 is
incorporated by reference in Part III, Items 9, 10, 11 and 12 of this Form
10-KSB.


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                                     PART I

        When used in this discussion, the words "believes", "anticipates",
"expects", and similar expressions are intended to identify forward-looking
statements. Such statements are subject to certain risks and uncertainties which
could cause actual results to differ materially from those projected.

         The Company's business and results of operations are affected by a wide
variety of factors that could materially and adversely affect the Company and
its actual results, including, but not limited to, the ability to obtain
governmental approvals on additional products, the impact of competitive
products and pricing, product demand and market acceptance, new product
development, reliance on key strategic alliances, availability of raw materials
and the regulatory environment. As a result of these and other factors, the
Company may experience material fluctuations in future operating results on a
quarterly or annual basis (including, to the extent appropriate governmental
approvals are not obtained, the inability to manufacture and sell products),
which could materially and adversely affect its business, financial condition,
operating results, and stock price. An investment in the Company involves
various risks, including those referred to above and those which are detailed
from time-to-time in the Company's filings with the Securities and Exchange
Commission, including this Form 10-KSB.

        These forward-looking statements speak only as of the date hereof. The
Company undertakes no obligation to publicly release the results of any
revisions to these forward-looking statements which may be made to reflect
events or circumstances after the date hereof or to reflect the occurrence of
unanticipated events.

Item 1.  Description of Business

Introduction

        Global Pharmaceutical Corporation (the "Company" or "Global") is a
specialty pharmaceutical company engaged principally in the development,
manufacture and marketing of solid oral generic prescription drugs primarily
targeting niche markets. The Company is headquartered at its 113,000
square-foot, state-of-art research and manufacturing facility located in
Philadelphia, PA., and is incorporated in Delaware.

     Global was formed in April 1993 to acquire the manufacturing plant,
equipment and certain related assets and liabilities (the "Facility") and the
Abbreviated New Drug Applications ("ANDAs"), New Drug Applications ("NDAs") and
New Animal Drug Applications ("NADAs") of Richlyn Laboratories, Inc.
("Richlyn"). Richlyn operated a generic pharmaceutical business from 1947 to
1992 when the Facility was closed for failure to comply with Food and Drug
Administration ("FDA") regulations concerning current Good Manufacturing
Practices ("cGMP").

     From its inception through 1997, the Company devoted substantially all of
its efforts to improving and renovating the Facility, establishing policies and
procedures to bring the Facility into compliance with cGMP, and obtaining all
government approvals necessary to begin operating the Facility. In July 1997,
the Company was notified that, following an inspection, FDA had determined that
Global's Tetracycline Hydrochloride 250 mg capsules had been validated. The
Company commenced operations and began shipping the product in September 1997.
During the remainder of 1997 the FDA routinely inspected and approved the work
necessary for each of Global's product introductions. In January 1998, the FDA
informed the Company that product-by-product inspections and authorizations
would no longer be required for the Company's current ANDA product portfolio.

     Since the start of operations, the Company introduced to market twenty
products; a table containing these products and related information is listed in
the Products and Product Development section later in this Form 10-KSB.

     The Company's strategic policy is to develop a broad product line, targeted
at niche markets, composed of solid oral (tablets and capsules) prescription,
generic drugs, various products that require isolation during their production,
narcotic and other drug products that are heavily regulated by the United States
Drug Enforcement Agency ("DEA"). In August 1997, the Company received approval
from DEA to manufacture Class II through V controlled substance products. The
Company also intends to seek to develop or license certain brand name
pharmaceutical products.

                                       1
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     In addition, the Company intends to expand its line of generic products
through a combination of a research and development program that is expected to
result in new products owned by the Company, as well as the licensing of
additional products owned by others. Generally, it is important that a new
generic product be approved by FDA for marketing by, or shortly after, the
patent expiration date of the equivalent brand name drug (plus any
legislatively-granted extensions) in order to gain significant market share at
attractive profit margins. As more generic products compete in the same market,
which customarily occurs increasingly over time following the brand name
product's patent expiration date (and extensions, if any), unit prices and
profit margins decrease. As the development of a new generic drug product,
including its formulation, testing and FDA approval, generally currently takes
approximately three or more years, development activities may begin several
years in advance of the patent expiration date of the brand name drug
equivalent. Consequently, the Company may select drugs for development several
years in advance of their anticipated entry to market. The Company intends to
enter larger, more competitive generic markets at such times as it believes it
can effectively compete in those markets.

     Positioning itself to effectuate this strategy, in January 1997, the
Company entered into an agreement (the "Genpharm Agreement") with Genpharm, Inc.
("Genpharm"), a Canadian corporation and an indirect subsidiary of Merck KGaA, a
German corporation, pursuant to which the Company shall supply packaging or has
supplied capacity available with respect to Genpharm's United States Ranitidine
Form I ("Ranitidine") production requirements based on a five-year cost-plus and
percentage of profits compensation arrangement, commencing in August 1997, when
Genpharm received ANDA approval for Ranitidine from FDA. Ranitidine is the
generic equivalent of Glaxo Wellcome plc's ("Glaxo") patented prescription drug
Zantac(R). The Company received and recognized as revenue approximately $445,000
in royalties from Genpharm for the year ended December 31, 1998.

        In addition to the packaging of Ranitidine, the Genpharm Agreement
provides the Company with the opportunity to develop products for the U.S.
market with the assistance of Merck KGaA. During 1998, the Company filed ANDA's
for two products selected under the Genpharm Agreement.

     Also, in August 1997 the Company signed two exclusive ten-year licensing
agreements with Eurand America ("Eurand"), a unit of American Home Products, an
international drug company that specializes in oral drug delivery. One agreement
provides for Eurand to supply the Company with a specified dosage of
Pancrelipase, a pancreatic enzyme used primarily by cystic fibrosis patients to
aid in digestion, for the generic market. The second agreement provides for
Eurand to develop and manufacture for Global, on an exclusive basis, several
Pancrelipase products using a new Eurand technology, and grants to the Company
an exclusive ten-year license to market and sell the products in the United
States subject to minimum sales levels. Currently, the Company is marketing two
products: Lipram 4500 and Lipram 10,000.

     In July 1998, the Company entered into a revolving credit facility with GE
Capital Corporation, providing funding to the Company of up to $5 million based
on levels of accounts receivable and inventory. Amounts borrowed under this
credit facility bear interest, payable monthly, at the Index Rate plus 4% per
annum. The Index Rate is the latest rate for 30-day dealer placed commercial
paper published in the "Money Rates" section of The Wall Street Journal.

     In November 1998, the Company issued 9,000 shares of Series C Convertible
Preferred Stock and a five year warrant to purchase 225,000 shares of common
stock at an initial exercise price equal to $4.00 per share for proceeds of
$900,000.

          On March 2, 1999, the Company issued 30,000 shares of Series D
Convertible Preferred Stock and a five year warrant to purchase 375,000 shares
of common stock at an initial exercise price equal to $4.00 per share for
aggregate proceeds of $3,000,000. The agreement between the Company and the
investors provides for the issuance, prior to June 30, 1999, of an additional
$2,000,000 of Series D Preferred Stock and a five year warrant to purchase
250,000 shares of common stock at an initial exercise price equal to $4.00 per
share, subject to authorization by the Company's stockholders of additional
shares of common stock and customary closing conditions.

Products and Product Development

     The Company's policy is to develop a broad product line composed of solid
oral (tablets and capsules) prescription, generic drugs and various products
that require isolation during their production. The Company also intends to seek
to develop, license or acquire certain brand name pharmaceutical products.

                                       2
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     The Company also plans to manufacture and sell drugs that are regulated by
DEA such as narcotics, barbiturates and certain tranquilizers, as well as
certain products that require isolated manufacturing facilities, which the
Company has provided by refurbishing and equipping a part of its existing
facility. DEA regulations generally deal with the storage and dissemination of
certain drugs and related raw materials and are designed to protect the security
of those products and their dissemination against receipt by unauthorized
persons. The Company believes that the DEA regulations that will be applicable
to it will not materially increase the scope or expense of its regulatory
compliance requirements.

      The Company acquired from Richlyn 54 ANDAs, NDAs and NADAs and more than
100 previously marketed prescription and OTC formulations including
pharmaceutical products not subject to FDA approval that were manufactured and
sold by Richlyn. Six of these ANDAs were validated and are currently marketed.
In addition, fourteen other products were introduced to market as of March 9,
1999. The following table contains a list of the twenty products the Company
currently market:
<TABLE>
<CAPTION>
- --------------------------------------------------------------------------------------------------------------------------
GLOBAL PRODUCT                                          STRENGTH  BRAND PRODUCT*         PRESCRIBED USE
- --------------------------------------------------------------------------------------------------------------------------
<S>                                                     <C>                              <C>             
Aminobenzoate Potassium Capsules                        0.5 gram  Potaba                 Anti-fibrotic
- --------------------------------------------------------------------------------------------------------------------------
Aminobenzoate Potassium Tablets                         0.5 gram  Potaba                 Anti-fibrotic
- --------------------------------------------------------------------------------------------------------------------------
Aminobenzoate Potassium Packets                           2 gram  Potaba                 Anti-fibrotic
- --------------------------------------------------------------------------------------------------------------------------
Chloroquine Phosphate Tablets                             250 mg  Aralen                 Anti-malarial
- --------------------------------------------------------------------------------------------------------------------------
Guaifenesin and Pseudoephedrine HCl ER Tablets      600 mg/120mg  Zephrex LA             Cough/cold
- --------------------------------------------------------------------------------------------------------------------------
Hyoscyamine Oral Tablets                                0.125 mg  Levsin                 Anticholinergic/antispasmodic
- --------------------------------------------------------------------------------------------------------------------------
Hyoscyamine Sublingual Tablets                          0.125 mg  Levsin                 Anticholinergic/antispasmodic
- --------------------------------------------------------------------------------------------------------------------------
Hyoscyamine Extended Release Tablets                    0.375 mg  Levbid                 Anticholinergic/antispasmodic
- --------------------------------------------------------------------------------------------------------------------------
Lipram 4500 (Pancrelipase) Capsules                   4500 units  Pancrease              Pancreatic enzyme replacement
- --------------------------------------------------------------------------------------------------------------------------
Lipram 10,000 (Pancrelipase) Capsules               10,000 units  Creon 10               Pancreatic enzyme replacement
- --------------------------------------------------------------------------------------------------------------------------
Mephobarbital Tablets CIV                                  32 mg  Mebaral                Sedative/anticonvulsant
- --------------------------------------------------------------------------------------------------------------------------
Mephobarbital Tablets CIV                                  50 mg  Mebaral                Sedative/anticonvulsant
- --------------------------------------------------------------------------------------------------------------------------
Mephobarbital Tablets CIV                                 100 mg  Mebaral                Sedative/anticonvulsant
- --------------------------------------------------------------------------------------------------------------------------
Methyltestosterone Tablets CIII                            10 mg  Testred/Android        Hormone replacement
- --------------------------------------------------------------------------------------------------------------------------
Methyltestosterone Tablets CIII                            25 mg  Testred/Android        Hormone replacement
- --------------------------------------------------------------------------------------------------------------------------
Oxycodone HCl Tablets CII                                   5 mg  Roxicodone             Analgesic
- --------------------------------------------------------------------------------------------------------------------------
Pancrelipase Tablets                                  8000 units  Viokase                Pancreatic enzyme replacement
- --------------------------------------------------------------------------------------------------------------------------
Promethazine HCl Tablets                                   25 mg  Phenergan              Antihistamine
- --------------------------------------------------------------------------------------------------------------------------
Tetracycline HCl Capsules                                 250 mg  Achromycin V           Antibiotic
- --------------------------------------------------------------------------------------------------------------------------
Tetracycline HCl Capsules                                 500 mg  Achromycin V           Antibiotic
- --------------------------------------------------------------------------------------------------------------------------
</TABLE>
*    The brand names listed are trademarks of the various companies represented.

<PAGE>

     The Company's current pipeline comprises of two ANDAs awaiting FDA
approval, five non-ANDA products, two reintroductions of previously approved
ANDA products, a series of line extensions to the LIPRAM line of Pancrelipase
capsules which are licensed from Eurand and six additional products in various
stages of development which will require ANDA submissions. It is expected that
up to three ANDAs may be filed during 1999. The current development project with
Eurand includes development of the second of the new technologies previously
licensed by the Company. It is anticipated that in addition to the line
extensions this technology may also result in a lower cost of goods for these
products.

Raw Materials

     The raw materials that will be essential to the Company's business are
expected to be bulk pharmaceutical chemicals which are generally available and
purchased from numerous sources. Because FDA requires specification of raw
material suppliers in applications for approval of drug products, if raw
materials from a specified supplier were to become unavailable, the required FDA
approval of a new supplier could cause a significant delay in the manufacture of
the drug involved. Although the Company expects to specify more than one raw
materials supplier with respect to each FDA application where that is possible,
some materials are currently available from only one or a limited number of
suppliers, as a result of which the Company would be subject to the special
risks that are associated with limited sources of supply. The Company plans to
purchase bulk pharmaceutical chemicals pursuant to multi-shipment contracts,
typically of one year's duration, when it believes advance-ordered bulk
purchases are advantageous to assure availability at a specified price. The
Company believes that alternative sources could be found, or new sources would
arise, should any of its sole or limited source raw materials become unavailable
from current suppliers. Nevertheless, any curtailment of raw materials could be
accompanied by production or other delays as well as increased raw materials
costs, with consequent adverse effects on the Company's business and results of
operations. Furthermore, as any new source of raw materials, whether domestic or
foreign, would require FDA approval, any delays in obtaining FDA approval could
also have a material adverse effect on the Company's business and operating
results.

                                       3
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     Following a general trend in the pharmaceutical industry, an increasing
portion, anticipated to be a majority over time, of the Company's raw material
supplies may come from foreign sources. Export and import policies of the United
States and foreign countries therefore could also materially affect the
availability and cost to the Company of certain raw materials at any time or
from time to time.

Quality Control

     In connection with the manufacture of drugs, FDA requires testing
procedures to monitor the quality of the product as well as the consistency of
its formulation. The Company maintains a state-of-the-art laboratory that
performs, among other things, analytical tests and measurements required to
control and release raw materials and finished products.

     Quality monitoring and testing programs and procedures have been
established by the Company to assure that all critical activities associated
with the production, control and distribution of its drug products will be
carefully controlled and evaluated throughout the process. By following a series
of systematically organized steps and procedures, the Company seeks to assure
that established quality standards will be achieved and built into the product.

     The Company's policy is to continually seek to meet the highest quality
standards, with the goal of thereby assuring the quality, purity, safety and
efficacy of each of its drug products. The Company believes that adherence to
high operational quality standards will also promote more efficient utilization
of personnel, materials and production capacity.

Sales and Marketing

     The Company markets solid oral prescription pharmaceuticals primarily
directed to the generic sector of the pharmaceutical market (also known as the
"multisource pharmaceutical market"). The distribution of these products is
primarily through the traditional pharmaceutical supply channels, including, but
not limited to, National Wholesalers Drug Association ("NWDA") wholesalers,
warehousing drug store chains, generic distributors, managed healthcare
providers, mail-order pharmacies, hospitals and institutions, governmental
agencies, and independent pharmacies.

     Presently, the Company concentrates its sales and marketing efforts on the
most prolific supply chain partners. Their national presence provides access to
a greater number of customers and patients. Moreover, these supply chain
partners support the process and help generate product demand.

     As the manufacturers of cost-effective, multisource pharmaceuticals
increased their reach and overall placement of products, customers began relying
on longer term arrangements with suppliers. The Company has entered into several
multi-year, multi-product agreements with various customers, including chains,
managed healthcare providers, governmental agencies and group purchasing
organizations. The product requirements of these contract customers are
satisfied by utilizing the traditional pharmaceutical supply channels.

     Marketing efforts are expected to extend beyond the ordinary promotional
vehicles; Global plans to reach the decision makers, including physicians and
dispensing pharmacists, with campaigns designed to develop awareness of some of
the Company's exclusive pharmaceutical alternatives. By increasing awareness of
these new generic entities, Global can provide customers a choice by offering
similar therapies at a fraction of the cost of brand products.

     In many ways 1998 was a transitional year for the Company. By progressing
from a development stage to a fully operational company, much of the primary
focus shifted toward gaining acceptance of Global Pharmaceutical and its product
by various customers in the pharmaceutical supply channels. To that end, the
Company was successful in gaining acceptance at all of the top 10 pharmaceutical
wholesalers, several of the top 10 warehousing drug store chains, managed
healthcare providers and governmental agencies both directly and indirectly,
through contracts. Additionally, the Company has successfully entered in other
new business, including two contract development projects and two contract
packaging projects. The Company plans to continue to pursue this type of new
business in order to increase utilization of its Facility and infrastructure.
There can be no assurance that the Company will be successful in the pursuit of
this business.

                                       4
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Competition

     Competition in the generic industry is intense. The Company is in
competition with numerous other companies in that industry, including major
pharmaceutical concerns and other exclusively generic manufacturers, most of
whom have significantly greater resources.

     The originator of a pharmaceutical product generally markets the product
under its own brand name during the life of the product's patent and any
statutory extensions of the patent. Companies introducing a product after the
patent (and any extension) expires may market the product under a brand name and
promote it to physicians and pharmacists to create a market for the product or
may market the product under its generic name and rely on physicians,
pharmacists and customers to specify the lower cost generic product. Producers
of brand name pharmaceutical products are also involved in the generic
marketplace, due to their concurrent marketing of both generic and brand name
versions of their products after their patents have expired.

     Some of the Company's competitors may choose to augment their presence in
the generic drug market through acquisitions and strategic alliances. This
activity could result in consolidation and restructuring within the generic
industry and could impair the Company's ability to compete effectively or
effectively limit the number of new opportunities for the Company's products.

     The principal competitive factors in the generic pharmaceutical market are
the ability to introduce generic versions of products promptly after a patent
expires, price, quality of products, customer service (including maintenance of
inventories for timely delivery), breadth of product line and the ability to
identify and market niche products. Approvals for new products may have a
synergistic effect on a company's entire product line as orders for new products
are frequently accompanied by, or bring about, orders for other products
available from the same company. Price is usually the major competitive factor
with respect to a generic product, but as more generic products enter a given
market, their prices, and hence their profit margins, decrease and competition
increasingly is based primarily on quality of product and service.

Proprietary Rights

     The Company does not own any patents and does not believe that patent
protection is material to its business. The Company may in the future be
required or may desire to obtain other licenses to develop, manufacture and
market commercially viable products in the future. There can be no assurance
that any licenses, if needed or desired by the Company, will be obtainable on
commercially reasonable terms or that any licensed patents or proprietary rights
will be valid and enforceable. Further, should the Company become subject to any
claim that it is violating the patent rights of another person, the Company
could be subject to costly litigation and, possibly, material liability. The
Company carefully monitors trademarks used by pharmaceutical companies,
including product trademarks, through regularly published and readily available
sources. Further, as the Company's generic products will only be manufactured
and sold by the Company after their respective brand name products' patents have
expired, and as the Company sells its products under generic, chemical names, it
believes the likelihood of it infringing on the patents of others is and will
continue to be remote.

Government Regulation

   Industry Regulation

     All pharmaceutical manufacturers are extensively regulated by the federal
government, including the FDA, the DEA and various State agencies. The Federal
Food, Drug, and Cosmetic Act, the Controlled Substances Act, the Generic Drug
Enforcement Act of 1992 and other federal statutes and regulations govern or
influence the manufacture, labeling, testing, storage, recordkeeping, approval,
advertising and promotion of the Company's products. Noncompliance with
applicable requirements can result in fines, recalls, seizure of products,
suspension of production, refusal of the government to enter into supply
contracts or to approve drug applications, and criminal prosecution.

     FDA approval is required before any "new drug" may be distributed in
interstate commerce. A drug that is the generic equivalent of a previously
approved prescription drug (i.e., the reference drug) also requires FDA
approval. Many over-the-counter drugs also require FDA pre-approval if the
over-the-counter drug is not covered by or does not conform with the conditions
specified in an applicable OTC Drug Product Monograph. All facilities engaged in
the manufacture of drug products must be registered with FDA and are subject to
FDA inspection to ensure that drug products are manufactured in accordance with
cGMP.

                                       5
<PAGE>

     Generally, two types of applications are used to obtain FDA approval of a
new drug. They are:

          1. New Drug Application ("NDA"). For drug products with active
     ingredients or indications not previously approved by FDA, a prospective
     manufacturer must submit a complete application which contains the results
     of clinical studies supporting the drug's safety and efficacy. An NDA may
     also be submitted for a drug with a previously approved active ingredient
     if the abbreviated procedure discussed below is not available. Currently,
     FDA approval of an NDA, on average, is estimated to take approximately 24
     to 26 months.

          2. Abbreviated New Drug Application ("ANDA"). The Drug Price
     Competition and Patent Term Restoration Act of 1984 (the "Drug Price Act")
     established an abbreviated new drug application procedure for obtaining FDA
     approval of certain generic drugs. An ANDA is similar to an NDA except that
     the FDA waives the requirement for conducting clinical studies to
     demonstrate the safety and effectiveness of the drug. Instead, for drugs
     that contain the same active ingredient and are the same route of
     administration, dosage form, strength and indication(s) as drugs already
     approved for use in the United States, FDA ordinarily only requires
     bioavailability data illustrating that the generic drug formulation is
     bioequivalent to the previously approved reference drug. "Bioavailability"
     indicates the rate of absorption and levels of concentration of a drug in
     the blood stream which are needed to produce a therapeutic effect.
     "Bioequivalence" compares the bioavailability of one drug product with
     another and, when established, indicates that the rate of absorption and
     the levels of concentration of a generic drug in the body do not show a
     significant difference from those of the previously approved equivalent
     drug. According to information published by FDA, it currently takes
     approximately 18 to 20 months on average to obtain FDA approval of an ANDA
     following the date of its first submission to FDA.

     The Drug Price Act created new statutory protections for approved brand
name drugs. Prior to enactment of the Drug Price Act, FDA gave no consideration
to the patent status of a previously approved drug in deciding whether to
approve an ANDA. Under the Drug Price Act, the effective date of approval of an
ANDA can depend, under certain circumstances, on the patent status of the brand
name drug. Additionally, the Drug Price Act, in certain circumstances, can
extend the term of certain patents to cover a drug for up to five additional
years. Any such extension is intended to compensate the patent holder for the
reduction of the effective market life of a patent due to the time involved in
federal regulatory review. With respect to certain drugs that are not covered by
patents, the Drug Price Act sets specified time periods of two to ten years
during which ANDAs for generic drugs cannot become effective or, under certain
circumstances, be filed if the equivalent brand name drug was approved after
December 31, 1981.

     Among the requirements for new drug approval is the requirement that the
prospective manufacturer's facility, production methods and recordkeeping
practices, among other factors, conform to cGMP. The cGMP must be followed at
all times when the approved drug is manufactured. In complying with the
standards set forth in the GMP regulations, the manufacturer must expend time,
money and effort in the areas of production and quality control to ensure full
technical compliance. Failure to comply can result in possible FDA actions such
as the suspension of manufacturing or seizure of finished drug products. The
Company also is governed by federal, state and local laws of general
applicability, such as laws regulating working conditions.

     The Generic Drug Enforcement Act of 1992 establishes penalties for
wrongdoing in connection with the development or submission of an ANDA. In
general, FDA is authorized to temporarily bar companies or temporarily or
permanently bar individuals from submitting or assisting in the submission of an
ANDA and to temporarily deny approval and suspend applications to market
off-patent drugs under certain circumstances. In addition to debarment, FDA has
numerous discretionary disciplinary powers, including the authority to withdraw
approval of an ANDA or to approve an ANDA under certain circumstances and to
suspend the distribution of all drugs approved or developed in connection with
certain wrongful conduct.

     The Company is also subject to the Maximum Allowable Cost Regulations ("MAC
Regulations"), which limit reimbursements for certain multi-source prescription
drugs under Medicare, Medicaid and other programs to the lowest price at which
such drugs are generally available. In many instances, only generic prescription
drugs fall within the MAC Regulations' limits. Generally, the methods of
reimbursement and fixing of reimbursement levels are under active review by
federal, state and local governmental entities as well as by private third-party
reimbursers. The Company cannot predict the results of those reviews or their
impact on the business of the Company.

                                       6
<PAGE>

     Virtually every state as well as the District of Columbia has enacted
legislation permitting the substitution of equivalent generic prescription drugs
for brand name drugs where authorized or not prohibited by the prescribing
physician and currently 13 states mandate generic substitution in Medicaid
programs.

     Environmental Laws

     The Company is subject to comprehensive federal, state and local
environmental laws, including the Comprehensive Environmental Response,
Compensation and Liability Act of 1980, as amended, the Resource Conservation
and Recovery Act and the Toxic Substance Control Act, which govern, among other
things, all emissions, waste water discharge and solid and hazardous waste
disposal, and the remediation of contamination associated with generation,
handling and disposal activities. The Company is subject periodically to
environmental compliance reviews by various regulatory offices.

     A Phase I environmental study was conducted with respect to the Company's
idled plant and operations in 1993 and certain environmental compliance issues
identified at that time, including findings of asbestos in certain areas of the
plant and underground oil storage tanks, have been addressed. Additionally, the
Company monitors regularly its compliance with any applicable Environmental
Laws. There can be no assurance that future developments, administrative actions
or liabilities relating to environmental matters will not have a material
adverse effect on the Company's financial condition or results of operations.

Litigation and Product Liability

     The Company's operations are subject to an order ("the Richlyn Order")
issued on May 25, 1993, by the United States District Court for the Eastern
District of Pennsylvania. The Richlyn Order, among other things, permanently
enjoined Richlyn from introducing into commerce any drug manufactured,
processed, packed or labeled at Richlyn's manufacturing facility unless Richlyn
met certain stipulated conditions, including successful compliance with a
validation and recertification program as described below. The Company, having
acquired certain assets of Richlyn, is obligated by the terms of the Richlyn
Order. The Richlyn Order also requires that the Company hire and retain a
person, subject to FDA approval, who, by reason of training and expertise, is
qualified to inspect the Company's drug manufacturing facilities to determine
that its methods, facilities and controls are operated and administered in
compliance with cGMP. The Richlyn Order further requires that the person so
retained both will inspect the Company's manufacturing facilities and its manner
of operating them and will examine all drug products manufactured, processed,
packed and held at the Company's Facility; and will certify in writing to FDA
the Company's compliance with related cGMP. The Company has retained an
independent consultant to serve in respect of the Richlyn Order.

     Additionally, the Company has assumed the liabilities of Richlyn in
connection with Diethyl Stilbestrol ("DES"), which was manufactured by Richlyn
and many other drug manufacturers during the late 1950's and early 1960's. DES
was prescribed to pregnant women during that period and has been alleged to
cause birth defects, in particular an increased risk of uterine cancer and
sterility to female children whose mothers took DES during their pregnancy.
There have been numerous claims brought against drug manufacturers in connection
with DES. Since 1987, Richlyn's insurers have paid approximately $136,000 on
Richlyn's and the Company's behalf to settle approximately 143 DES-related
suits. The Company is unaware of any other legal actions having been brought or
threatened against Richlyn or the Company in connection with DES-related claims.
The Company believes that all DES-related legal actions have been directed
towards individual manufacturers and not been embodied in a class action, and,
as such, does not expect to be held liable for DES-related claims other than
claims based on products manufactured by Richlyn. While Richlyn's insurers have
in the past defended those DES claims against Richlyn and paid settlements in
connection therewith to date, those insurers have reserved their right to
discontinue the defense of the claims and the payment of any settlements at any
time. There can be no assurance or guarantee that the insurers will defend
actions or pay claims in the future. Further, there can be no assurance that, if
those insurers fail or refuse to pay any claim, the Company will have recourse
against the insurers with respect thereto. Accordingly, there can be no
assurance that the Company will not be exposed to the risk of substantial
monetary judgments. Claims settlements to date have been based upon market share
and Richlyn's share of the market during the periods in question was
substantially less than 1%. The Company does not believe the Richlyn DES
liabilities will have a material adverse effect on the Company's business.

     Product liability claims by customers constitute a risk to all
pharmaceutical manufacturers. The Company carries $10 million of product
liability insurance for its own manufactured products. The Company believes that
this insurance will be adequate for its foreseeable purposes and is comparable
to product liability insurance carried by similar generic drug companies.

                                       7
<PAGE>

     The Company is not aware of other material pending or threatened legal
actions, private or governmental, against the Company.

Employees

     As of March 9, 1999, the Company employed approximately 64 full-time
persons. Of those employees, approximately 26 work in the quality area, 23 are
in operations, 8 are in administration, 3 are in product development and 4 work
in sales and marketing. The Company may also employ part-time personnel from
time to time to meet specific demands of its business should they arise. None of
the Company's employees are subject to collective bargaining agreements with
labor unions. The Company believes that its relations with its employees, in
general, are satisfactory.

Executive Officers

       The following table sets forth certain information with respect to the
executive officers and significant employees of the Company:
<TABLE>
<CAPTION>

- --------------------------------------------------------------------------------------------------------------------
                 Name                        Age                                 Position
- --------------------------------------------------------------------------------------------------------------------
<S>                                          <C>     <C>                                                 
Barry R. Edwards                             42       President, Chief Executive Officer and a Director
- --------------------------------------------------------------------------------------------------------------------
Cornel C. Spiegler                           54       Chief Financial Officer and Vice President - Administration.
- --------------------------------------------------------------------------------------------------------------------
Marc M. Feinberg                             49       Vice President - Quality and Regulatory Affairs
- --------------------------------------------------------------------------------------------------------------------
Mitchell Goldberg                            47       Vice President - Sales and Marketing
- --------------------------------------------------------------------------------------------------------------------
Pieter J. Groenewoud                         44       Vice President - Product Development
- --------------------------------------------------------------------------------------------------------------------
Joseph A. Storella                           57       Vice President - Operations
- --------------------------------------------------------------------------------------------------------------------
</TABLE>

     Barry R. Edwards joined the Company in April 1998 and has been President
since August 1998 and Chief Executive Officer and a director of the Company
since January 1999. From 1996 to 1998, Mr. Edwards was Vice President, Marketing
and Business Development for Teva Pharmaceuticals USA, a manufacturer of generic
drugs. From 1991 to 1996, Mr. Edwards served as Executive Director of Gate
Pharmaceuticals, a division of Teva Pharmaceuticals USA. Prior to 1991, Mr.
Edwards held a number of management functions in strategic planning, corporate
development, business development and marketing at Teva Pharmaceuticals USA.

     Cornel C. Spiegler has been Chief Financial Officer and Vice
President--Administration since September 1995. From 1989 to 1995, Mr. Spiegler
was Chief Financial Officer and Senior Vice President of United Research
Laboratories, Inc. and Mutual Pharmaceutical Company, Inc., companies engaged in
the generic pharmaceutical industry. From 1973 to 1989, Mr. Spiegler held a
number of financial and operational management functions, including Vice
President and Controller of Fischer and Porter, Inc., a manufacturer of process
control equipment. From 1970 to 1973, Mr. Spiegler was employed by the
accounting firm of Arthur Andersen and Co. Mr. Spiegler is a certified public
accountant.

     Marc M. Feinberg has been Vice President - Quality and Regulatory Affairs
since October 1996. Prior to joining the Company, from 1995 to 1996, Mr.
Feinberg served as Vice President - Quality Assurance and Regulatory Affairs for
the JWS Delavau Company, a contract manufacturer and packager of nutritional and
over-the-counter products. From 1989 to 1995, Mr. Feinberg held the position of
Vice President - Quality Assurance for Packaging Coordinators, Inc., a contract
packager for the pharmaceutical industry. From 1985 to 1989, Mr. Feinberg served
as Manager, Quality Assurance for ICI Pharmaceuticals Group. From 1972 to 1985,
Mr. Feinberg served as Senior Drug Investigator for the U.S. Food and Drug
Administration.

     Mitchell Goldberg has been Vice President - Sales and Marketing since March
1997. From October 1996 until March 1997, Mr. Goldberg served as Vice President
- - Sales and Marketing for Ethex Corporation, a generic manufacturing company.
From 1985 to October 1996, Mr. Goldberg held a number of sales and marketing
management positions with Schein Pharmaceutical, Inc., a generic pharmaceutical
company. From 1980 to 1985, Mr. Goldberg served in sales positions for
Pharmavite Corporation, a nutritional supplement manufacturer.

     Pieter J. Groenewoud has been Vice President - Product Development since
May 1996. From October 1995 to May 1996, Mr. Groenewoud served as Chief
Operating Officer of the Company. From 1992 to 1995, Mr. Groenewoud served as
General Manager of Vintage Pharmaceutical Inc., a manufacturer of generic drug
pharmaceutical products. From 1990 to 1992, Mr. Groenewoud was Project Manager
for Pennex Products Company Inc., a generic drug company. From 1988 to 1990, Mr.
Groenewoud was Vice President of Quality Control at Medicopharma Inc., a
manufacturer of pharmaceutical products, and formerly held the position of Vice
President of Operations from 1986 to 1988.

                                       8
<PAGE>

     Joseph A. Storella has been Vice President - Operations since May 1996.
From 1986 to 1996, Mr. Storella served as General Manager of Chelsea
Laboratories, formerly a division of Rugby-Darby Group Companies which, in 1993
was purchased by Marion Merrell Dow and subsequently purchased by The Hoechst
Company. From 1977 to 1986, Mr. Storella served as Vice President - Operations
of Analytab Products, Inc., a division of Ayerst Laboratories (which itself is a
division of American Home Products). From 1966 to 1977, Mr. Storella held a
number of operational management positions for Ayerst Laboratories.

Item 2.  Description of Property

     The executive offices and research, warehouse and production facilities of
the Company occupy an aggregate of approximately 113,000 square feet at Castor
and Kensington Avenues in Philadelphia, Pennsylvania. The Company's principal
executive offices are part of that overall facility.

     The Company owns its plant, which consists of three three-story brick
interconnected buildings that were constructed between 1900 and 1930. The
interior of the plant has been substantially renovated and modernized since 1993
and includes a new dust collection system and special environmental control
units for humidity and temperature. The land and the building serve as partial
collateral for two Pennsylvania Industrial Development Authority ("PIDA") loans.
See Item 6, Management's Discussion and Analysis or Plan of Operation--Liquidity
and Capital Resources.

     Of the total 113,000 square foot area of the plant, approximately 20,000
square feet are used for warehousing and storage operations, (including high
security DEA areas and designated areas for raw materials, processed goods,
labels and packaging materials); approximately 11,000 square feet are devoted to
manufacturing operations; approximately 13,700 square feet for maintenance
operations; approximately 10,000 square feet for laboratory, quality assurance
and quality control activities, including batch testing and stability testing
operations; approximately 5,000 square feet are for labeling and packaging
activities; approximately 2,500 square feet for product development; and
approximately 9,000 square feet are for administrative functions. The unused
balance of the plant, approximately 41,800 square feet, is available for future
expansion. Management believes that the Company's production facilities are
sufficient for its current and reasonably anticipated operations.

     The Company maintains an extensive equipment base, much of it new or
recently reconditioned and automated, including manufacturing equipment for the
production of tablets; coated tablets, and capsules; packaging equipment,
including fillers, cottoners, cappers and labelers; and a well-equipped, modern
laboratory. The manufacturing equipment includes mixers and blenders for
capsules and tablets, automated capsule fillers, tablet presses, particle
reduction, sifting equipment and tablet coaters. The Company also maintains a
broad variety of material handling and cleaning, maintenance and support
equipment. The Company owns substantially all of its manufacturing equipment and
believes that its equipment is well maintained and suitable for its
requirements.

     The Company maintains property and casualty and business interruption
insurance in amounts it believes are sufficient and consistent with practices
for companies of comparable size and business.

Item 3.  Legal Proceedings

     The Company is not a party to, nor is any of its properties the subject of,
any material pending legal proceedings. See Item 1, "Description of
Business--Litigation and Product Liability" for a description of certain legal
matters with respect to the Company.

Item 4.  Submission of Matters to a Vote of Security Holders

      None
                                       9
<PAGE>
                                     PART II

Item 5.  Market for Common Equity and Related Stockholder Matters

     The Company's Common Stock is traded on the NASDAQ Small Cap Market under
the symbol "GLPC". The following are the high and low per share bid prices of
the Company's Common Stock on the NASDAQ Small Cap Market since December 19,
1995, the date of the Company's IPO. Such prices represent quotations or prices
between dealers and do not include retail mark-up, mark-down or commission and
may not necessarily represent actual transactions:
<TABLE>
<CAPTION>

Quarter Ended                   High             Low           Quarter Ended            High       Low
- -------------                 --------        --------         -------------           ------    -------     
<S>      <C> <C>              <C>             <C>             <C>                     <C>       <C>
December 31, 1995             $10             $ 9              March 31, 1998          $5 3/4    $ 2 3/4
March 31, 1996                $12 5/8         $11              June 30, 1998           $5 3/8    $ 2 7/8
June 30, 1996                 $11             $10 1/8          September 30, 1998      $3 5/8    $ 1 1/2
September 30, 1996            $ 9 1/4         $ 8              December 31, 1998       $2 3/8    $13/16
December 31, 1996             $ 8 7/8         $ 6 1/2
March 31, 1997                $ 9 5/8         $ 6 7/8
June 30, 1997                 $ 8 3/8         $ 4
September 30, 1997            $ 7 1/2         $ 3 3/4
December 31, 1997             $ 5 1/2         $ 2 3/4
</TABLE>

     On March 9, 1999, the last reported bid price of the Common Stock on the
NASDAQ Small Cap Market was $2 3/8 per share. As of March 22, 1999, there were
approximately 88 holders of record of common stock and approximately 498
beneficial owners of common stock.

     The Company has never paid cash dividends on its Common Stock and has no
present plans to do so in the foreseeable future. The Company's current policy
is to retain all earnings, if any, for use in the operation of its business. The
payment of future cash dividends, if any, will be at the discretion of the Board
of Directors and will be dependent upon the Company's earnings, financial
conditions, capital requirements and other factors as the Board of Directors may
deem relevant.

     In November 1998, the Company completed the sale of $900,000 of its Series
C Mandatorily Redeemable Convertible Preferred Stock. All of the shares of the
Company's common stock into which the Preferred Stock is convertible
(approximately 450,000 shares of common stock at March 9, 1999) was subsequently
registered for resale under the U.S. Federal securities laws.

     On March 2, 1999, the Company completed the initial sale of $3,000,000 of
its Series D Mandatorily Redeemable Convertible Preferred Stock. An additional
$2,000,000 of its Series D Preferred Stock is expected to close prior to June
30, 1999 subject to authorization by the Company's stockholders of additional
shares of common stock.

Item 6.  Management's Discussion and Analysis or Plan of Operation

General

     The Company was formed in April 1993 to acquire the manufacturing plant,
equipment and certain related assets (the "Facility") and the ANDAs, NDAs and
NADAs of Richlyn. Richlyn operated as a generic pharmaceutical business from
1947 to 1992. Richlyn ceased operations at the Facility in 1992 as a result of
failure to comply with FDA regulations concerning cGMP. See Item 1, "Description
of Business."

     In December 1995, the Company completed its initial public offering of
common stock ("IPO") in which 1,650,000 shares of common stock were sold for net
proceeds of $11,489,000. An additional 247,500 shares of common stock were sold
to the underwriter of the IPO in January 1996, upon the exercise of the
underwriter's over-allotment option for net proceeds to the Company of
$1,835,000.

                                       10
<PAGE>

     From its inception through 1997, the Company has devoted substantially all
of its efforts to improving and renovating the Facility, establishing policies
and procedures to bring the Facility into compliance with cGMP, and obtaining
all government approvals necessary to begin operating the Facility. In July
1997, the Company was notified that, following an inspection, FDA had determined
that Global's Tetracycline Hydrochloride 250 mg capsules had been validated. The
FDA subsequently determined that sufficient data was available to assign an
expiration date to the product's label and the Company commenced operations and
began shipping the product in September 1997. Since Global commenced operations,
the FDA has routinely inspected and approved the work necessary for each of
Global's product introductions. In January 1998, the FDA informed the Company
that product-by-product inspections and authorizations would no longer be
required for the Company's current ANDA product portfolio.

     Through March 9, 1999, Global has introduced to market 20 products see Item
1, "Description of Business".

     The Company cannot currently predict whether its business will be seasonal
in nature, but to the extent that it manufactures and distributes products that
pertain to seasonal ailments such as allergies or colds, the Company may
experience seasonal patterns in its sales and profitability. There can be no
assurance that the potential seasonality of the Company's business will not have
a material adverse effect on the Company. In addition, the Company's revenues,
and hence its profitability, if any, may vary significantly from fiscal quarter
to fiscal quarter as well as in comparison to the corresponding quarter of the
previous year as a result, among other factors, of the timing of process
validation for particular generic drug products, the timing of any significant
initial shipments of newly approved drugs and competitive pressures from other
generic drug manufacturers who receive FDA approvals covering competing
products.

     In August 1997, Global signed two exclusive ten year licensing agreements
with Eurand America Inc. ("Eurand"), an international drug company that
specializes in oral delivery. Eurand is a unit of American Home Products, one of
the world's largest research-based pharmaceutical and healthcare companies.
Under the first agreement, Eurand develops, manufactures and supplies to Global
several dosages of Pancrelipase, a pancreatic enzyme used primarily by cystic
fibrosis patients to aid in digestion using a new Eurand technology, and grants
Global an exclusive license to market and sell the products in the United States
subject to minimum sales levels. The second agreement provides for Eurand to
supply Global with the existing Eurand Pancrelipase 4500 USP Lipase content
product, for the generic market; this product is currently marketed as Lipram
4500. Another Eurand manufactured product, Lipram 10,000, was introduced in June
1998.

Results of Operations

     Until the quarter ended December 31, 1997, when Global became operational,
the Company was considered a development stage company as defined in Statement
of Financial Accounting Standards No. 7

     Since its inception through 1997, the Company has devoted substantially all
of its efforts to improving and renovating the Facility, establishing policies
and procedures to bring the Facility into compliance with cGMP, and obtaining
all government approvals necessary to begin operating the Facility.

     The year ended December 31, 1998 was the Company's first full year of
operations with $4,401,000 in revenues. The Company had an accumulated deficit
of $22,591,000 at December 31, 1998.

Year Ended December 31, 1998 compared to Year Ended December 31, 1997.

     The Company's net loss for the year ended December 31, 1998 was $4,615,000,
as compared to a net loss of $5,877,000 for the year ended December 31, 1997.
The decrease in the net loss was due primarily to increased revenues . Also,
during 1998 the Company issued Series C Convertible Preferred Stock which
resulted in non-cash imputed dividends which increased the net loss applicable
to common stock by $140,000 or $0.03 per share to $4,755,000 or $1.07 per share.

     In 1997, the Company issued Series A and Series B Convertible Preferred
Stock which resulted in non-cash imputed dividends which increased the net loss
applicable to common stock by $2,547,000 or $0.59 per share to $8,424,000 or
$1.97 per share.

     Net sales for the year ended December 31, 1998 were $4,401,000 as compared
to $427,000 for the year ended December 31, 1997. The increase in net sales of
$3,974,000 was due primarily to an increase in number of products and customers
realized in 1998 as compared to 1997. Also, the Company was operational for only
three months in 1997, as compared to a full year of operations in 1998.

                                       11

<PAGE>

     Cost of sales of $4,681,000 for the year ended December 31, 1998 had
associated cost of goods sold of $2,064,000 and an unabsorbed manufacturing
overhead of $2,617,000 representing the undercapacity utilization of the plant
and infrastructure. For the year ended December 31, 1997, the comparable
operational costs were estimated at $3,388,000 including $321,000 reported as
cost of sales and $3,067,000 reported as part of general and administrative
expense.

     Research and development costs for the year ended December 31, 1998 were
$2,229,000. Research and development costs for the year ended December 31, 1997
were estimated at $561,000 and were reported as part of general and
administrative expenses. The increase in research and development costs in 1998
as compared to 1997 was primarily due to biostudy costs for the two ANDAs,
development costs to Eurand and additional personnel expenses.

     Selling expenses for the year ended December 31, 1998 were $759,000.
Selling expenses for the year ended December 31, 1997 were estimated at $215,000
and were reported as part of general and administrative expenses. The increase
in selling expenses in 1998 as compared to 1997 was primarily due to additional
personnel, travel and advertising expenses and sales commissions.

     General and administrative expenses were $1,778,000 for the year ended
December 31, 1998. The amount reported as general and administrative expenses
for the year ended December 31, 1997, when Global was still a development stage
company, was $6,164,000, and included operational, research and development and
selling expenses.

     Interest expense was $113,000 for the year ended December 31, 1998 as
compared to $65,000 for the year ended December 31, 1997, due to additional
borrowings from the Pennsylvania Industrial Development Authority ("PIDA") and
the Delaware River Port Authority ("DRPA") through the Philadelphia Industrial
Development Corporation ("PIDC") and the short-term borrowing from the General
Electric Capital Corporation ("GECC") Credit Facility.

     Interest income was $137,000 for the year ended December 31, 1998 as
compared to $124,000 for the year ended December 31, 1997 due to an increase in
investments in cash equivalents resulting primarily from the proceeds of the
Series B Preferred Stock issuance.

     Other income of $479,000 for the year ended December 31, 1998 primarily
comprised of $445,000 of royalties received under the Genpharm distribution
agreements. Other income of $122,000 generated during the year ended December
31, 1997 was due primarily to an amount received from a supplier for a claim
relating to unacceptable materials purchased from the supplier.

     Other expense of $72,000 for the year ended December 31, 1998 represents
costs for a nonrecurring profit sharing arrangement with a sales organization
for the distribution of one of the Company's products.

Liquidity and Capital Resources

     Until the Company's IPO, the Company financed its activities primarily
through the issuance of promissory notes to the family that previously
controlled Richlyn, low interest borrowings, proceeds from the private placement
of equity securities, and loans from stockholders.

     In December 1995, the Company completed its IPO in which 1,650,000 shares
of common stock were sold by the Company for net proceeds of $11,489,000. An
additional 247,500 shares of common stock were sold to the underwriter of the
IPO in January 1996, for net proceeds to the Company of $1,835,000.

     In July 1997, the Company received a $758,000 loan from PIDA bearing annual
interest of 3.75% for 15 years and a $350,000 loan from the DRPA via the PIDC
bearing annual interest of 5.00% for 10 years. These loans are secured by land,
building and building improvements. A portion of the loans funded capital
projects, with the remaining proceeds invested in interest bearing certificates
of deposit owned by the Company and pledged as additional collateral.

                                       12
<PAGE>
     The Company completed an initial closing of approximately $1.2 million of
its Series A Convertible Preferred Stock in August 1997, and a subsequent
closing of $150,000 in September 1997. In addition, the Company completed the
closing of $5 million of its Series B Convertible Preferred Stock in December
1997. In connection with these offerings, at December 31, 1997, the Company
incurred aggregate expenses, of approximately $196,000, resulting in net
proceeds to the Company of approximately $6.1 million. The Company used the
proceeds from these offerings for working capital purposes. As of March 2, 1999,
all the shares of Series A and Series B Preferred Stock were converted to common
stock.

     In July 1998, the Company entered into a revolving credit facility with GE
Capital, providing financing to the Company of up to $5 million based on levels
of accounts receivable and inventory. Amounts borrowed under the credit facility
bear interest, payable monthly, at the Index Rate plus 4% per annum. The Index
Rate is the latest rate for 30-day dealer placed commercial paper published in
the "Money Rates" section of The Wall Street Journal. The Company also pays a
fee of .125% per annum on the unused available portion of the credit line. At
December 31, 1998 the Company had outstanding borrowings of $804,000 with
additional availability of $373,000.

     In November 1998, the Company issued 9,000 shares of Series C Convertible
Preferred Stock and a five year warrant to purchase 225,000 shares of common
stock at an initial exercise price equal to $4.00 per share, for proceeds of
$900,000. The proceeds were used for working capital purposes.

       On March 2, 1999, the Company issued 30,000 shares of Series D
Convertible Preferred Stock and a five year warrant to purchase 375,000 shares
of common stock at an initial exercise price equal to $4.00 per share, for
aggregate proceeds of $3,000,000. The agreement between the Company and the
investors provides for the issuance, prior to June 30, 1999, of an additional
$2,000,000 of its Series D Convertible Preferred Stock and a five year warrant
to purchase 250,000 shares of common stock at an initial exercise price equal to
$4.00 per share subject to authorization by the Company's stockholders of
additional shares of common stock. The proceeds of this private placement will
go towards funding research and development efforts, working capital and general
corporate needs.

       The Company has adequate financing for its 1999 operational plan, even if
the Company does not receive stockholders' approval for additional shares of
common stock.

The Year 2000 Issue

     The Company's computer system and programs were designed in recent years
and concerns related to the Year 2000 issue were addressed at the time the
decision to purchase the system was made. During 1998 management initiated a
program to prepare the Company's computer systems, applications and other
equipment that may employ date sensitive embedded chips for the year 2000. The
Company has been advised by its hardware and software vendors that all databases
used by current systems are Year 2000 compliant. The Company completed an
inventory of all computer hardware and software applications and successfully
tested their Year 2000 compliance. The Company is in the process of addressing
the Year 2000 issues with customers, suppliers, service providers and other
constituents which should be completed by June 30, 1999. The Company will review
the information received in response to these inquiries and will determine the
need and extent of contingency planning. The Company will complete its
contingency planning by July 31, 1999. At this time, the Company does not
believe that the Year 2000 issue indicates a material event or uncertainty or
that the cost of addressing the Year 2000 issue is material to the Company's
business, operations or financial condition.

Risk of the Company's Year 2000 Issues

     Achieving Year 2000 compliance is dependent on many factors, some of which
are not completely within the Company's control. There can be no assurance that
the Company will be able to identify all aspects of its business that are
subject to Year 2000 problems of customers or suppliers that affect the
Company's business. There also can be no assurance that the Company's software
vendors are correct in their assertions that the software is year 2000
compliant, or that the Company's estimate of the costs of systems preparation
for Year 2000 compliance will prove ultimately to be accurate. Should either the
Company's internal systems or internal systems of one or more significant
suppliers or customers fail to achieve Year 2000 compliance, or the Company's
estimate of the costs of becoming Year 2000 compliant prove to be materially
inaccurate, the Company's business and its results of operations could be
adversely affected.

New Financial Accounting Standards

     In June 1997, the Financial Accounting Standards Board (FASB) issued
Statement of Financial Accounting Standards ("SFAS") No. 130, "Reporting
Comprehensive Income," which established standards for reporting and display of
comprehensive income and its components in a financial statement that is
displayed with the same prominence as other financial statements. Comprehensive
income includes all changes in equity during a period from all transactions
other than those with stockholders, including net income, foreign currency
related items and unrealized gain or loss on certain securities. The disclosures
prescribed by this standard had no effect on the Company for the year ended
December 31, 1998.
                                       13
<PAGE>

     Also in 1997, the FASB issued SFAS No. 131, "Disclosures about Segments of
an Enterprise and Related Information", which established guidance for
disclosure of business segment information in annual financial statements. The
statement had no impact on the Company as it operates in one business segment:
generic pharmaceuticals.

     In 1998, the FASB issues SFAS No. 132, "Employers' Disclosures about
Pensions and Other Postretirement Benefits." This standard revises and
standardizes disclosure requirements for pension and other postretirement
benefits in annual financial statements. This statement had no impact on the
Company as the Company has no pension or other postretirement plans which
require disclosure.

     In 1998, the FASB issued SFAS No. 133, "Accounting for Derivative
Instruments and Hedging Activities," which establishes a new model for the
accounting and reporting of derivative and hedging transactions. The statement
amends a number of existing standards and is effective for fiscal years
beginning after June 15, 1999. The Company is assessing this statement, but
believes it will have no impact on the Company.

     Also in 1998, the AICPA issued SOP 98-1, "Accounting for Internally
Developed Software," with required adoption for most companies beginning in
1999. This SOP provides guidelines for the capitalization of certain internal
software development costs. The Company will adopt this standard in 1999, but
does not believe it will have significant impact on its financial results.

Item 7.  Financial Statements and Supplementary Data

     The financial statements and supplementary data required by this Item begin
on page F-1 of this Annual Report on Form 10-KSB.

Item 8.  Changes in and Disagreements with Accountants on Accounting and 
         Financial Disclosures

     None

                                    PART III

Item 9.  Directors, Executive Officers, Promoters and Control Persons; 
         Compliance with Section 16(a) of the Exchange Act

     The information contained under the heading "Proposal No. 1 - Election of
Directors" in the Company's definitive Proxy Statement (the "Proxy Statement")
relating to the Company's Annual Meeting of Stockholders scheduled to be held on
or about May 12, 1999, to be filed pursuant to Regulation 14A of the Securities
Exchange Act of 1934 with the Securities and Exchange Commission is incorporated
herein by reference. For information concerning the executive officers and other
significant employees of the Company, see "Business - Executive Officers" in
Item 1 above of this Annual Report.

Item 10.   Executive Compensation

     The response to this item will be included in the Company's Proxy Statement
to be used in connection with the Annual Meeting of Stockholders scheduled to be
held on May 12, 1999 and is incorporated herein by reference.

Item 11.   Security Ownership of Certain Beneficial Owners and Management

     The response to this item will be included in the Company's Proxy Statement
to be used in connection with the Annual Meeting of Stockholders scheduled to be
held on May 12, 1999 and is incorporated herein by reference.

Item 12.   Certain Relationships and Related Transactions

     The response to this item will be included in the Company's Proxy Statement
to be used in connection with the Annual Meeting of Stockholders scheduled to be
held on May 12, 1999 and is incorporated herein by reference.

                                       14
<PAGE>

Item 13.   Exhibits, Lists and Reports on Form 8-K

           a)  Exhibits
<TABLE>
<CAPTION>
Exhibit
Number                                    Description of Document
- -------                                   -----------------------
<S>        <C>                                                                                  
 2.1       Agreement and Plan of Merger among the Company, Management Stockholders and
           Toledex Acquisition Corporation, dated as of April 6, 1995. (1)

 2.2       Certification of Merger between Toledex Acquisition Corporation and the Company,
           dated April 6, 1995. (1)

 3.1       Restated Certificate of Incorporation of the Company. (1)

 3.2       Certificate of the Designations, Powers, Preferences and Rights of the Series A
           Convertible Preferred Stock of the Company. (3)

 3.3       Certificate of the Designations, Powers, Preferences and Rights of the Series B
           Convertible Preferred Stock of the Company. (6)

 3.4       Certificate of the Designations, Powers, Preferences and Rights of the Series C
           Convertible Preferred Stock of the Company (9).

 3.5       Certificate of Amendment to Certificate of the Designations, Powers, Preferences and 
           Rights of the Series A and Series B Convertible Preferred Stock (9).

 3.6       By-laws of the Company. (1)

 4.1       Specimen Certificate of the Company's Common Stock, par value $.01 per share. (1) 

 4.2       Form of Representative's Warrant Agreement between the Company and the
           Representative, including form of Representative's Warrant Certificate. (1)

10.1       Employment Agreement of Pieter Groenewoud, dated as of October 1, 1995. (1)

10.2       Employment Agreement of Cornel C. Spiegler, dated as of September 27, 1995. (1)

10.6       The Company's 1995 Stock Incentive Plan. (1)

10.9       Form of Amended Agreement between the Company and Merck Kommanditgesellschaft auf
           Aktien regarding the issuance of Common Stock Purchase Warrants, dated as of
           November, 1995. (1)

10.10      Form of Amended Manufacturing Agreement between the Company and Genpharm, Inc.,
           dated as of November, 1995. (1)

10.18      Acquisition Agreement between PIDC-Financing Corporation and GPC Florida, dated
           September 17, 1993. (1)

10.19      Security Agreement by and between the Company and PIDC Local Development Corporation, 
           dated October 15, 1993, with related Note and Commitment, and Waiver and Consent dated
           November 13, 1995. (1)

10.21      Loan Agreement by and between PIDC Financing Corporation and the Pennsylvania Industrial
           Development Authority ("PIDA") for a loan in a principal amount not to exceed $1,026,000,
           dated April 18, 1994, with Waiver and Consent dated November 13, 1995. (1)

10.22      Open-End Mortgage between PIDC Financing Corporation and PIDA dated April 18, 1994. (1)
10.25      Assignment of Installment Sale Agreement by and among PIDC Financing Corporation,
           PIDA and GPC Florida, dated April 18, 1994. (1)

10.26      Installment Sale Agreement by and between PIDC Financing Corporation and GPC
           Florida dated April 18, 1994. (1)

10.27      PIDC Financing Corporation Note to the PIDA, dated April 18, 1994. (1)
</TABLE>
                                       15
<PAGE>
<TABLE>
<CAPTION>

<S>       <C>        
10.28      Secured $500,000 Note from the Company to PIDC Local Development Corporation. (1)

10.29      Consent, Subordination and Assumption Agreement by and among GPC Florida,  PIDC
           Financing Corporation and PIDA, dated April 18, 1994. (1)

10.37      Form of Escrow Agreement by and among the Company, the Representative and
           Continental Stock Transfer and Trust Company. (1)

10.39      Employment agreement by and between the Company and Marc M. Feinberg dated
           September 30, 1996. (2)

10.40      Technical Collaboration Agreement by and between the Company and Genpharm Inc.
           dated January 8, 1997. (4)

10.42      Employment agreement by and between the Company and Mitchell Goldberg dated March
           13, 1997. (4)

10.43      Development, License and Supply Agreement with Eurand America, Inc. dated August
           20, 1997. (5)

10.44      License and Supply Agreement with Eurand America, Inc. dated August 20, 1997 (5)
10.45      Employment agreement by and between the Company and Barry Edwards dated March 25,
           1998.

10.46      Loan and Security Agreement dated as of July 23, 1998 between General Electric Capital
           Corporation as Lender and Global Pharmaceutical Corporation as Borrower.

11.1       Statement Regarding Computation of Earnings Per Share. (1)

23.1       Consent of Price Waterhouse LLP. (1)

27         Financial Data Schedule

99.1       Court Order issued May 25, 1993 by the United States District Court for the
           Eastern District of Pennsylvania against Richlyn Laboratories, Inc. (1)
</TABLE>
- ------------------------------------------------------------------------------
(1) Previously filed with the Commission as Exhibits to, and incorporated herein
    by reference from, the Registrant's Registration Statement on Form SB-2
    (File No. 33-99310-NY)

(2) Previously filed with the Commission as Exhibits to, and incorporated herein
    by referenced from, the Registrant's Quarterly Report on Form 10-QSB for the
    quarterly period ended September 30, 1996.

(3) Previously filed with the Commission as Exhibit 3.3 to, and incorporated
    herein by reference from, the Registrant's Registration Statement on Form
    S-3 (File No. 333-35569)

(4) Previously filed with the Commission as Exhibits to, and incorporated herein
    by reference from the Registrant's Yearly Report on Form 10-KSB for the year
    ended December 31, 1996.

(5) Previously filed with the Commission as Exhibits to, and incorporated herein
    by reference from, the registrant's Quarterly Report on Form 10-QSB for the
    quarterly period ended September 30, 1997.

(6) Previously filed with the Commission as Exhibit 3.3 to, and incorporated
    herein by reference from, the Registrant's Registration Statement on Form
    S-3 (File No. 333-44217) 

(7) Previously filed with the Commission as Exhibit to, and incorporated herein
    by reference from, the Registrant's Quarterly Report on form 10-QSB for the
    quarterly period ended June 30, 1998. 

(8) Previously filed with the Commission as Exhibit 3.3 to, and incorporated
    herein by reference from, the Registrant's Quarterly Report on form 10-QSB
    for the quarterly period ended September 30, 1998. 

(9) Previously filed with the Commission as Exhibit 3.3 to, and incorporated
    herein by reference from the Registrant's Registration Statement on Form S-3
    (File No. 333-69395).

           b) Reports on Form 8-K.

                  No reports on Form 8-K were filed during the last quarter of
the year ended December 31, 1998.

                                       16
<PAGE>
                                   SIGNATURES

In accordance with Section 13 or 15(d) of the Exchange Act, the registrant
caused this report to be signed on its behalf by the undersigned, thereunto duly
authorized.

                   GLOBAL PHARMACEUTICAL CORPORATION


                   By   /s/ Barry R. Edwards
                        --------------------------------------------------------
                        Barry R. Edwards, President and Chief Executive Officer

                   Date    3-24-99
                        ---------------

In accordance with the Exchange Act, this report has been signed below by the
following persons on behalf of the registrant and in the capacities and on the
dates indicated.



                /s/ BARRY R. EDWARDS              President and Chief Executive
             --------------------------           Officer and Director 
                   (Barry R. Edwards)             (Principal Executive      
                                                  Officer)                  
                                                       


               /s/ CORNEL C. SPIEGLER             Chief Financial Officer, Vice
             --------------------------           President--Administration
                  (Cornel C. Spiegler)            (Principal Financial and      
                                                  Accounting Officer)           
                                                       


                /s/ PHILIP R. CHAPMAN             Director
             --------------------------
                  (Philip R. Chapman)


                  /s/ GARY ESCANDON               Director
             --------------------------
                  (Gary Escandon)

               /s/ G. THOMAS FINNEGAN             Director
             --------------------------
                  (G. Thomas Finnegan)


                 /s/ GEORGE F. KEANE              Director
             --------------------------
                 (George F. Keane)


               /s/ MICHAEL MARKBREITER            Director
             --------------------------
                 (Michael Markbreiter)


                /s/ MAX L. MENDELSOHN             Director
             --------------------------
                 (Max L. Mendelsohn)

                                                   
                  /s/ JOHN W. ROWE                Director
             --------------------------
                     (John W. Rowe)


                  /s/ UDI TOLEDANO                Director
             --------------------------
                     (Udi Toledano)

                                       17

<PAGE>

                        GLOBAL PHARMACEUTICAL CORPORATION

                          INDEX TO FINANCIAL STATEMENTS

<TABLE>
<CAPTION>

                                                                                                          Page(s)
                                                                                                          -------
<S>                                                                                                  <C>
Report of Independent Accountants.................................................................           F-2

Balance Sheet at December 31, 1998 and December 31, 1997 .........................................           F-3

Statement of Operations for each of the three years ended December 31, 1998.......................           F-4

Statement of Changes in Stockholders' Equity (Deficit) for each of the three years ended
December 31, 1998.................................................................................           F-5

Statement of Cash Flows for each of the three years ended December 31, 1998. .....................           F-6

Notes to Financial Statements.....................................................................   F-7 to F-15
</TABLE>

All financial statement schedules are omitted because they are not required.





                                      F-1

<PAGE>


                        REPORT OF INDEPENDENT ACCOUNTANTS

To the Board of Directors
 and Stockholders of Global Pharmaceutical Corporation

In our opinion, the accompanying balance sheet and the related statements of
operations, of changes in stockholders' equity (deficit) and of cash flows
present fairly, in all material respects, the financial position of Global
Pharmaceutical Corporation (the Company) at December 31, 1998 and 1997, and the
results of its operations and its cash flows for each of the three years in the
period ended December 31, 1998, in conformity with generally accepted accounting
principles. These financial statements are the responsibility of the Company's
management; our responsibility is to express an opinion on these financial
statements based on our audits. We conducted our audits of these statements in
accordance with generally accepted auditing standards which require that we plan
and perform the audit to obtain reasonable assurance about whether the financial
statements are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements, assessing the accounting principles used and significant estimates
made by management, and evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for the opinion expressed
above.



PRICEWATERHOUSECOOPERS LLP






Philadelphia, Pennsylvania
March 2, 1999

                                      F-2

<PAGE>
                        GLOBAL PHARMACEUTICAL CORPORATION

                                  BALANCE SHEET
                 (in thousands, except share and per share data)
<TABLE>
<CAPTION>
                                                                                 December 31,  
                                                                        -----------------------------
                                                                          1998                 1997
                                                                        --------              -------
<S>                                                                      <C>                  <C> 
ASSETS
Current assets:
     Cash and cash equivalents.....................................      $ 1,304              $ 4,719
     Accounts receivable ..........................................        1,088                  215
     Inventories ..................................................          763                  386
     Prepaid expenses and other ...................................           51                   46
                                                                         -------              -------
          Total current assets.....................................        3,206                5,366
Property, plant and equipment, net.................................        4,054                4,077
Intangible assets, net of accumulated amortization of $294 and $59.          883                1,118
Deferred financing costs, net......................................           26                   32
Investments .......................................................          684                  729
                                                                         -------              -------
          Total assets.............................................      $ 8,853              $11,322
                                                                         =======              =======
LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIT)
Current liabilities:
     Current portion of long-term debt.............................      $   161              $   158
     Notes payable ................................................          804                   --
      Accounts payable..............................................         927                  673
     Accrued expenses..............................................        1,019                  649
                                                                         -------              -------
          Total current liabilities................................        2,911                1,480
Long-term debt.....................................................        1,967                2,129
                                                                         -------              -------
                                                                           4,878                3,609
                                                                         -------              -------
Commitments and contingencies (Note 13)

Mandatorily redeemable convertible Preferred Stock (Notes 10, 11 and 14): 
     Series A mandatorily redeemable convertible Preferred Stock,
          11,280 and 13,350 shares outstanding at December 31,                  
          1998 and 1997, respectively; $.01 par value, redeemable 
          at $100 per share .......................................        1,128                1,335
     Series B mandatorily redeemable convertible Preferred Stock,
          43,255 and 50,000 shares outstanding at December 31,
          1998 and 1997, respectively; $.01 par value, redeemable                         
          at $100 per share  ......................................        4,326                5,000                         
     Series C mandatorily redeemable convertible Preferred Stock,       
          9,000 shares outstanding; $.01 par value, redeemable 
          at $100 per share .......................................          900                   --
                                                                         -------              -------
                                                                           6,354                6,335
                                                                         -------              -------
Stockholders' equity (deficit):
     Preferred Stock, $.01 par value, 2,000,000 authorized, 72,350   
          shares issued and 63,535 outstanding at December 31, 
          1998; 63,350 shares issued and outstanding at 
          December 31, 1997 .......................................           --                  --

     Common Stock, $.01 par value, 10,000,000 authorized and
          4,656,097 and 4,286,871 shares issued and outstanding                            
          at December 31, 1998 and 1997, respectively .............           47                  43
     Additional paid-in capital....................................       20,165               19,311
     Accumulated deficit ..........................................      (22,591)             (17,976)
                                                                         -------              -------
          Total stockholders' equity (deficit).....................       (2,379)               1,378
                                                                         -------              -------
          Total liabilities and stockholders' equity (deficit).....      $ 8,853              $11,322
                                                                         =======              =======
</TABLE>
   The accompanying notes are an integral part of these financial statements.

                                      F-3

<PAGE>

                             STATEMENT OF OPERATIONS
             (dollars in thousands, except share and per share data)

                                                 Year Ended December 31,
                                        ----------------------------------------
                                           1998          1997           1996
                                        ----------    ----------     ----------
Net sales ...........................   $    4,401    $      427     $       --
Cost of sales .......................        4,681           321             --
                                        ----------    ----------     ----------
Gross margin (loss) .................         (280)          106             --
Research and development expense ....        2,229            --             --
Selling expense .....................          759            --             --
General and administrative expense ..        1,778         6,164          5,121
Interest expense ....................          113            65             40
Interest income .....................         (137)         (124)          (375)
Other income (Note 3) ...............         (479)         (122)          (178)
Other expenses ......................           72            --             --
                                        ----------    ----------     ----------
Net loss ............................       (4,615)       (5,877)        (4,608)

Less: Imputed dividends on
 Preferred Stock* ...................         (140)       (2,547)            --
                                        ----------    ----------     ----------
Net loss applicable to Common Stock .   $   (4,755)   $   (8,424)    $   (4,608)
                                        ==========    ==========     ==========
Net loss per common share (basic
 and diluted)* ......................   $    (1.07)   $    (1.97)    $    (1.08)
                                        ==========    ==========     ========== 
Weighted average common
 shares outstanding .................    4,432,016     4,286,871      4,269,967
                                        ==========    ==========     ==========


* The net loss per share applicable to Common Stock for the year ended December 
  31, 1997 includes Preferred Stock dividends of $2,547,000, or $0.59 per share,
  representing the difference between the per share conversion price and the
  market value of the Common Stock on the dates of issuance of the Series A and
  Series B Convertible Preferred Stock. The net loss per share for the year
  ended December 31, 1998 includes a Preferred Stock dividend of $140,000, or
  $0.03 per share, representing the difference between the fair market value and
  liquidation value of the Series C Preferred Stock at issuance date (See Note
  10).

   The accompanying notes are an integral part of these financial statements.

                                      F-4

<PAGE>

                        GLOBAL PHARMACEUTICAL CORPORATION

             STATEMENT OF CHANGES IN STOCKHOLDERS' EQUITY (DEFICIT)
                        (dollars and shares in thousands)
<TABLE>
<CAPTION>

                                                             Common stock                                       Total
                                                         -------------------  Additional                     stockholders'
                                                         Number of     Par      paid-in      Accumulated        equity
                                                           shares     value     capital        deficit         (deficit)
                                                         ---------   -------  ----------     -----------     -------------
<S>                                                     <C>        <C>        <C>           <C>               <C>    
Balances at December 31, 1995.........................      4,039     $  40     $17,575       $ (7,491)         $10,124
Issuance of common stock in January 1996 (Note 11)....        248         3       1,832             --            1,835
Net loss..............................................         --        --          --         (4,608)          (4,608)
                                                            -----     -----     -------       --------          -------          
Balances at December 31, 1996.........................      4,287        43      19,407        (12,099)           7,351
Issuance of Preferred Stock (Series A and B) .........         --        --       2,547             --            2,547
Accretion of Preferred Stock dividends (Series A                                          
  and B)..............................................         --        --      (2,547)            --           (2,547)
Expenses relating to issuance of Series A and Series B                                    
  Preferred Stock.....................................         --        --         (96)            --              (96)          
Net loss..............................................         --        --          --         (5,877)          (5,877)
                                                            -----     -----     -------       --------          -------          
Balances at December 31, 1997.........................      4,287        43      19,311        (17,976)           1,378
Expenses relating to issuance of Series B Preferred 
  Stock...............................................         --        --         (23)            --              (23)
Conversion of Series A and Series B Preferred Stock...        369         4         877             --              881
Issuance of Preferred Stock(Series C).................         --        --         140             --              140
Accretion of Preferred Stock dividend (Series C)......         --        --        (140)            --             (140)
Net loss..............................................         --        --          --         (4,615)          (4,615) 
                                                            -----     -----     -------       --------          -------           
Balances at December 31, 1998.........................      4,656     $  47     $20,165       $(22,591)         $(2,379)
                                                            =====     =====     =======       ========          =======
</TABLE>

   The accompanying notes are an integral part of these financial statements.

                                      F-5
<PAGE>


                        GLOBAL PHARMACEUTICAL CORPORATION

                             STATEMENT OF CASH FLOWS

                             (dollars in thousands)
<TABLE>
<CAPTION>

                                                                                 Year Ended December 31,
                                                                          --------------------------------------
                                                                            1998           1997           1996
                                                                          --------      ---------       --------
<S>                                                                       <C>            <C>            <C> 
Cash flows from operating activities:                                                                 
     Net loss ..................................................          $(4,615)       $(5,877)       $(4,608)
     Adjustments to reconcile net loss to net cash used by 
         operating activities:
         Depreciation and amortization..........................              708            455            281 
         Expenses recognized through issuance of warrants ......               10            101             -- 
         Change in assets and liabilities:
              (Increase) in accounts receivable.................             (873)          (215)            --
              (Increase) in inventory...........................             (377)          (386)            --            
              (Increase) decrease in  prepaid expenses and other                                  
                assets..........................................                1              3            (19)
              Increase (decrease) in accounts payable and    
                accrued expenses ...............................              624            520           (467)
                                                                          -------        -------        -------
                  Net cash used for operating activities........           (4,522)        (5,399)        (4,813)
                                                                          -------        -------        -------
Cash flows from investing activities:
     (Purchases) of property, plant and equipment...............             (450)          (335)        (2,311)
     Redemption (purchases) of marketable securities............               45           (729)            --
                                                                          -------        -------        -------                
                  Net cash used for investing activities........             (405)        (1,064)        (2,311)
                                                                          -------        -------        -------
Cash flows from financing activities:
     Long-term debt:
         Borrowings.............................................               --          1,108             -- 
         Payments...............................................             (159)          (108)          (185)
     Notes payable
         Borrowings ............................................              804             --             -- 
     Issuance of stock and warrants:
         Over-allotment exercise................................               --             --          1,835 
         Issuance of Preferred Stock, net of expense............              867          6,138             --
                                                                          -------        -------        -------
                  Net cash provided by financing activities.....            1,512          7,138          1,650
                                                                          -------        -------        -------
Net increase (decrease) in cash and cash equivalents............           (3,415)           675         (5,474) 
Cash and cash equivalents, beginning of period..................            4,719          4,044          9,518
                                                                          -------        -------        -------
Cash and cash equivalents, end of period........................          $ 1,304        $ 4,719        $ 4,044
                                                                          =======        =======        =======
Supplemental disclosure of cash flow information:
     Cash paid for interest.....................................          $   113        $    51        $    40
                                                                          =======        =======        =======
</TABLE>

For other supplemental disclosure of non-cash investing and financing
activities, see Notes 2, 3, and 10.



   The accompanying notes are an integral part of these financial statements.

                                      F-6
<PAGE>
                        GLOBAL PHARMACEUTICAL CORPORATION

                          NOTES TO FINANCIAL STATEMENTS

1.   Formation and Operation of the Company

     Purpose

     Global Pharmaceutical Corporation (the "Company") was formed in April 1993
to acquire the manufacturing plant, equipment and certain related assets and
liabilities (the "Facility") and the Abbreviated New Drug Applications
("ANDAs"), New Drug Applications ("NDAs") and New Animal Drug Applications
("NADAs") of Richlyn Laboratories, Inc. ("Richlyn"). Richlyn operated a generic
pharmaceutical business from 1947 to 1992; operations of the Facility had been
idled since September 1992 for failure to comply with Food and Drug
Administration ("FDA") regulations concerning current Good Manufacturing
Practices ("cGMP").

     From its inception through 1997, the Company devoted substantially all of
its efforts to improving and renovating the Facility, establishing policies and
procedures to bring the Facility into compliance with cGMP, and obtaining all
government approvals necessary to begin operating the Facility. On July 11, 1997
the Company was notified that, following an inspection, FDA had determined that
Global's Tetracycline Hydrochloride 250 mg capsules had been validated. The FDA
subsequently determined that sufficient data was available to assign an
expiration date to the product's label and the Company commenced operations and
began shipping the product in September 1997. Since Global commenced operations,
the FDA has routinely inspected and approved the work necessary for each of
Global's product introductions. On January 29, 1998, the FDA informed the
Company that product-by-product inspections and authorizations would no longer
be required for the Company's current ANDA product portfolio. As of March 2,
1999, the Company is shipping twenty products.

       The Company was considered a development stage company as defined in
Statement of Financial Accounting Standards No. 7 until the fourth quarter of
1997 when the Company determined it had begun operations.

     Funding of Activities

     To date, the Company has funded its efforts to engage in the manufacture,
repackaging and sale of solid oral prescription and over-the-counter generic
drugs and dietary supplements through equity and debt financings.

     In 1995, the Company completed its Initial Public Offer of Common Stock
("IPO") in which 1,650,000 shares of common stock were sold for net proceeds to
the Company of $11,488,000. In connection with the IPO, the underwriter received
an option to purchase up to 247,500 shares of common stock at $8.50 per share
(the "over-allotment"). The underwriter exercised this option in January 1996,
at which time the Company sold 247,500 shares of common stock for net proceeds
of $1,835,000.

     In 1997, the Company received a $758,000 loan from the Pennsylvania
Industrial Development Authority ("PIDA") at 3.75% annually fixed for 15 years
and a $350,000 loan from the Delaware River Port Authority ("DRPA") via the
Pennsylvania Industrial Development Corporation ("PIDC") at 5.00% annually fixed
for 10 years. These loans were partially used to fund capital projects, and are
secured by land, building and building improvements. From these proceeds, at
December 31, 1998, $684,000 is invested in interest bearing certificates of
deposit owned by the Company and pledged as additional collateral for these
loans.

     The Company completed closings of $6,335,000 of its Series A and B
mandatorily redeemable convertible Preferred Stock in 1997 and $900,000 of its
Series C mandatorily redeemable convertible Preferred Stock in November 1998.

     Also in 1998, the Company entered into a three year revolving credit
facility with GE Capital, providing funding to the Company of up to $5 million
based on levels of accounts receivable and inventory. At December 31, 1998, the
Company had outstanding borrowings of $804,000 on this facility, with $373,000
of availability.

     On March 2, 1999, the Company completed an initial closing of $3,000,000 of
its Series D Mandatorily Redeemable Convertible Preferred Stock to Fleming US
Discovery Fund III, L.P. and Fleming US Discovery Offshore Fund III, L.P.
(collectively "Flemings")(Note 14). An additional $2,000,000 of its Series D
Mandatorily Redeemable Convertible Preferred Stock to Flemings is expected to
close no later than June 30, 1999, subject to the Company's stockholders
authorization of additional shares of common stock. The Company has adequate
financing for its 1999 operational plan, even if the Company does not receive
Stockholders' approval for additional shares of common stock.

                                      F-7
<PAGE>

                        GLOBAL PHARMACEUTICAL CORPORATION

                    NOTES TO FINANCIAL STATEMENTS (continued)

2.   Summary of Significant Accounting Policies

     Cash and cash equivalents

     Cash and cash equivalents are stated at cost which approximates market
value. Cash equivalents include only securities having a maturity of three
months or less at the time of purchase.

     Concentration of credit risk

     Financial instruments which potentially subject the Company to
concentrations of credit risk are cash, cash equivalents, investments, and
accounts receivable. The Company limits its credit risk associated with cash,
cash equivalents and investments by placing its investments with highly rated
money market funds, U.S. Government securities, treasury bills and short-term
commercial paper. The Company limits its credit risk with respect to accounts
receivable by performing ongoing credit evaluations and, when deemed necessary,
requiring letters of credit, guarantees, or collateral.

     The Company has two customers which account for 38% of total sales for the
year ended December 31, 1998. At December 31, 1998, accounts receivable from
three customers represent 41% of total trade receivables. Approximately 47% of
the Company's net sales were attributable to one product family which is
supplied by a vendor under an exclusive licensing agreement.

     Inventories

     Inventories are stated at the lower of cost (determined on the basis of
first-in, first-out) or market. The Company considers product costs as inventory
once the Company receives FDA approval to market the related products.

     Property, plant and equipment

     Property, plant and equipment are recorded at cost. Maintenance and repairs
are charged to expense as incurred and costs of improvements and renewals are
capitalized. Costs incurred in connection with the construction or major
renovation of facilities, including interest directly related to such projects,
are capitalized as construction in progress. Depreciation is recognized using
the straight-line method based on the estimated useful lives of the related
assets.

     Intangible assets

     Intangible assets are comprised of ANDAs, NDAs and NADAs acquired from
Richlyn and are recorded at fair value. Amortization is recognized on a
straight-line basis over a five year period starting on October 1, 1997, when
operations commenced.

     The Company complies with Statement of Financial Accounting Standards No.
121, "Accounting for the Impairment of Long-Lived Assets and for Long-Lived
Assets to Be Disposed Of". Accordingly, the carrying value of long-lived assets
and certain identifiable intangible assets are evaluated whenever changes in
circumstances indicate the carrying amount of such assets may not be
recoverable. In performing such review for recoverability, the Company compares
expected future cash flows to the carrying value of long-lived assets and
identifiable intangibles. If the expected future cash flows (undiscounted) are
less than the carrying amount of such assets, the Company recognizes an
impairment loss for the difference between the carrying amount of the assets and
their estimated fair value.

     Deferred financing costs

     Deferred financing costs are amortized on a straight-line basis over the
terms of the respective debt instrument.

                                      F-8
<PAGE>

                        GLOBAL PHARMACEUTICAL CORPORATION

                    NOTES TO FINANCIAL STATEMENTS (continued)

     Investments

         The Company's investments in other than cash equivalents are classified
as "held-to-maturity" based upon the nature of the investments, their ultimate
maturity date, the restrictions imposed by the PIDA and PIDC loan agreements
dated July 29, 1997 (See Note 8) and management's intention with respect to
holding these securities. Realized gains and losses are determined on the basis
of specific identification of the securities sold. At December 31, 1998, the
cost of the Company's investments approximate fair value.

     Revenue recognition

     Revenues, net of applicable allowances, from product sales are recognized
upon shipment of product. Royalties are recognized when the related contract
provisions are met.

     Income taxes

     The Company utilizes the liability method of accounting for income taxes as
set forth in Statement of Financial Accounting Standards No. 109, "Accounting
for Income Taxes". Under this method, deferred tax liabilities and assets are
recognized for the expected future tax consequences of temporary differences
between the carrying amounts and the tax bases of assets and liabilities.
Valuation allowances are provided on deferred tax assets for which it is more
likely than not that some portion or all of the deferred tax asset will not be
realized.

     Earnings per share

     The Company reports both basic earnings per share, which is based on the
weighted-average number of common shares outstanding, and diluted earnings per
share, which is based on the weighted average number of common shares
outstanding and all dilutive potential common shares outstanding. Because the
Company had net losses in each of the years presented, only the weighted average
of common shares outstanding have been used to calculate both basic earnings per
share and diluted earnings per share as the inclusion of the potential common
shares would be anti-dilutive.

     Accounting for stock-based compensation

          The Company has elected to disclose the fair value of stock options
and other stock-based compensation issued to employees as a pro forma effect on
net income in the footnotes to the Company's financial statements rather than as
compensation expense in the Statement of Operations.

     Accounting estimates

     The preparation of financial statements in conformity with generally
accepted accounting principles requires management to make estimates and
assumptions that affect the reported amounts of assets, liabilities and
disclosure of contingencies at the date of the financial statements and the
reported expenses during the reporting period.
Differences from those estimates are recorded in the period they become known.

     Business segments

     The Company operates in one business segment, primarily in the generic
pharmaceuticals business.

                                      F-9
<PAGE>

                        GLOBAL PHARMACEUTICAL CORPORATION

                    NOTES TO FINANCIAL STATEMENTS (continued)

3.   Related Party Transactions

     On November 8, 1995, the Company entered into an agreement ( the "Genpharm
Agreement") with Genpharm, Inc., a Canadian corporation ("Genpharm"), an
indirect subsidiary of Merck KGaA under which Merck KGaA purchased 150,000
shares of the Company's common stock. The Company also issued to Merck KGaA a
warrant to purchase 100,000 shares of common stock at an exercise price of $2.00
per share, (the "A Warrant") and additional warrants to purchase up to 700,000
shares, at an exercise price of $8.50 per share (the IPO price per share), whose
exercise is contingent upon the gross profit (as defined in the agreement), if
any, earned by the Company under the Genpharm Agreement. In January 1997, the
Company revised its agreement with Genpharm, pursuant to which the Company shall
supply packaging, or has supplied capacity available, with respect to Genpharm's
United States Ranitidine production requirements based on a five-year cost-plus
and percentage of profits compensation arrangement following the receipt of the
requisite FDA Ranitidine approvals. In addition to the packaging of Ranitidine,
the Genpharm Agreement provides the Company with the opportunity to develop
products with the assistance of Merck KGaA that are marketed outside the U.S.
During 1998, the Company filed ANDA's for two products previously selected.

     The Company received and recognized as revenue approximately $445,000 in
royalties from Genpharm for the year ended December 31, 1998 which is included
in Other Income in the accompanying Statement of Operations.

4.   Inventories

     Inventories consist of the following:

                                                          December 31,
                                                     ---------------------
                                                      1998           1997
                                                      ----           ----
                                                    (dollars in thousands)
Raw materials..................................       $139           $ 44
Finished goods.................................        624            342
                                                      ----           ----
                                                      $763           $386
                                                      ====           ====

5.   Property, Plant and Equipment

     Property, plant and equipment consist of the following:
<TABLE>
<CAPTION>

                                                    Estimated           December 31,
                                                   useful life     ---------------------
                                                     (years)        1998           1997       
                                                   -----------     ------         ------      
                                                                   (dollars in thousands) 
    
<S>                                                    <C>         <C>            <C>               
Land ........................................           --         $   53         $   53            
Building.....................................           25            212            212                                   
Building improvements........................           15          3,047          2,983           
Production equipment.........................           10          1,309          1,097                                 
Laboratory equipment.........................            7            746            610       
Office furniture and equipment...............            5            184            157                              
Construction in progress.....................           --             18              7                                
                                                                   ------         ------
                                                                    5,569          5,119                                         
Less: Accumulated depreciation...............                      (1,515)        (1,042)
                                                                   ------         ------                   
                                                                   $4,054         $4,077 
                                                                   ======         ======                                   
</TABLE>

Depreciation expense was $473,000, $396,000 and $281,000 for the years ended
December 31, 1998, 1997, and 1996, respectively.

<PAGE>
 
6.  Accrued Expenses

     Accrued expenses consist of the following:
<TABLE>
<CAPTION>
                                                                                  December 31,
                                                                               ------------------
                                                                                1998         1997
                                                                               ------        ----
                                                                                 (in thousands)
<S>                                                                            <C>           <C> 
Accrued rebates and chargebacks .........................................      $  283        $ 10
Accrued professional fees ...............................................         327         353
Accrued salaries and payroll related expenses ...........................         124         109
Accrued development cost and royalty expense (Eurand - Note 13)..........         141          --            
Other ...................................................................         144         177
                                                                               ------        ----
                                                                               $1,019        $649
                                                                               ======        ====
</TABLE>

Rebates and chargebacks include reserves for price rebate programs for certain
products, chargebacks from wholesalers, and certain sales related items. Accrued
rebates and chargebacks at December 31, 1998 and 1997 represent management's
estimate of the Company's future obligation.

                                      F-10
<PAGE>
                        GLOBAL PHARMACEUTICAL CORPORATION

                    NOTES TO FINANCIAL STATEMENTS (continued)

7.   Income Taxes

     Due to the Company's losses since inception, no provision for income taxes
is recorded for any period. The difference between the federal statutory tax
rate and the Company's effective income tax rate is attributable to losses and
future tax deductions for which valuation allowances have been established.

The net deferred tax balance is comprised of the tax effects of cumulative
temporary differences, as follows:

                                                              December 31,
                                                       -----------------------
                                                         1998            1997
                                                       -------         -------
                                                             (in thousands)

Net operating losses.............................      $ 3,898         $ 1,142
Deferred start-up and organization costs.........        4,914           6,140
Eurand development costs (Note 13) ..............          274              92 
Depreciation and amortization....................          495             304
Other ...........................................           67              --
                                                       -------         -------
   Gross deferred tax assets.....................        9,648           7,678
Deferred tax asset valuation allowance...........       (9,648)         (7,678)
                                                       -------         -------
                                                       $    --         $    --
                                                       =======         =======

     Due to historical losses incurred by the Company and limitations on the
future use of net operating losses due to changes in the Company's ownership, a
full valuation allowance for net deferred tax assets has been provided. If the
Company achieves profitability, certain of these net deferred tax assets would
be available to offset future income taxes.

8.   Notes Payable

     In July 1998, the Company entered into a three year revolving credit
facility with G.E. Capital, providing funding to the Company up to $5 million
based on the levels of accounts receivable and inventory. Amounts borrowed under
this credit facility bear interest, payable monthly, at the Index Rate plus 4%
per annum. The Index Rate is the latest rate for 30-day dealer placed commercial
paper published in the "Money Rates" section of The Wall Street Journal. The
Company also pays a fee of .125% per annum on the unused available portion of
the credit line. At December 31, 1998, the Company had borrowings of $804,000
under this facility with $373,000 of availability.

9.   Long-Term Debt
<TABLE>
<CAPTION>
                                                                                              December 31,
                                                                                            1998           1997
                                                                                           ------        -------
                                                                                               (in thousands)
<S>                                                                                       <C>            <C> 
2% loan payable to PIDA (No. 1) in 180 monthly installments of $6,602
   commencing June 1, 1994 through May 1, 2009......................................       $  745         $  808
3.75% loan payable to PIDC in 84 monthly installments of $3,672 commencing January
   1, 1994, with a balance of $304,000 due on December 1, 2000......................          363            393
3.75% loan payable to PIDA (No. 2) in 180 monthly installments of $5,513 commencing                  
   September 1, 1997, through August 1, 2012........................................          707            745
5% loan payable to DRPA in 120 monthly installments of $3,712 commencing   
   September 1, 1997, through August 1, 2007........................................          313            341
                                                                                           ------         ------
                                                                                            2,128          2,287
Less: Current portion of long-term debt.............................................         (161)          (158)
                                                                                           ------         ------
                                                                                           $1,967         $2,129
                                                                                           ======         ======
</TABLE>

     The PIDC loan is secured by the Company's equipment. The PIDA (No. 1) loan
is secured by land, building and building improvements. The PIDC (No. 2) loan
and the DRPA loan are secured by land, building and building improvements, and
additional collateral of $684,000, invested in interest bearing certificates of
deposit owned by the Company.

                                      F-11
<PAGE>

                        GLOBAL PHARMACEUTICAL CORPORATION

                    NOTES TO FINANCIAL STATEMENTS (continued)

     The PIDA, PIDC/DRPA loans contain financial and non-financial covenants,
including certain covenants regarding levels of employment which were not
effective until the Company commenced operations. The Company received a waiver
with respect to a non-financial covenant at December 31, 1998, and is in
compliance with all other loan covenants.

     Scheduled maturities of long-term debt as of December 31, 1998 are as
follows, in thousands:


                           1999..................     $  161
                           2000..................        472
                           2001..................        144
                           2002..................        148
                           2003..................        153
                           Thereafter............      1,050
                                                      ------
                                    Total........     $2,128
                                                      ======

10.  Mandatorily Redeemable Convertible Preferred Stock

     The Company's Board of Directors authorized and designated 60,000, 50,000,
9,000 and 50,000 shares of Preferred Stock as Series A Preferred, Series B
Preferred, Series C Preferred and Series D Preferred, respectively, with all
shares priced at $100 per share. In 1997, the Company issued 13,350 shares of
Series A and 50,000 shares of Series B Preferred Stock to accredited investors
for 1,335,000 and $5,000,000, respectively.

     At the option of the holder, each share of Series A Preferred and Series B
Preferred Stock is convertible into that number of shares of the Company's
common stock as is determined by dividing the liquidation value of $100 per
share by the conversion price. At December 31, 1998, the conversion price was
the lower of $2.75 per share or the average closing sale price of the common
stock for the five trading days immediately preceding conversion but in no event
less than $2.00 per share. The difference between the $2.75 per share conversion
price and the market value of the common stock on the dates of the issuance of
Preferred Stock was recognized as a Preferred Stock dividend of $2,547,000 in
1997.

     In November 1998, the Company issued 9,000 shares of Series C Preferred
Stock and a five year warrant to purchase 225,000 shares of common stock at an
initial exercise price equal to $4.00 per share for proceeds of $900,000. The
Company allocated these proceeds by determining the fair value of the warrants
as being $140,000 using the Black-Scholes option-pricing model, with $760,000,
being allocated to Preferred Stock. The Company then recognized a $140,000
Preferred Stock Dividend to reflect the Series C Preferred Stock at its
liquidation value.

     At the option of the holder, each share of Series C Preferred Stock is
convertible into that number of shares of the Company's common stock as is
determined by dividing the liquidation value by the conversion price. The
conversion price is the lower of $2.00 per share or the average closing sale
price of the common stock for the five trading days immediately preceding
conversion but in no event less than $0.75 per share. In the event the Company,
within eighteen months from the Series C Preferred Stock initial closing, issues
and sells not less than an aggregate of $1 million of additional shares of
common stock (or securities convertible into common stock) for a consideration
per share of common stock of less than $2.00 the conversion price will be
reduced to a price equal to the consideration per share for which the additional
shares are sold.

     Except as required by law, holders of the shares of Series A , Series B,
Series C and Series D Preferred Stock vote on an as-converted basis, as a single
class with all other stockholders of the Company. Holders of Series D Preferred
also have certain voting rights with respect to major corporate transactions or
reorganization.

     Each share of Preferred Stock is entitled to a liquidation preference equal
to $100 per share before any distributions to holders of common stock, and
Series A, B, C and D Preferred Stock are not entitled to dividends unless
declared on common stock. The holders of Series C and Series D Preferred Stock
are entitled to a liquidation preference over the holders of Series A Preferred
and Series B Preferred Stock.

                                      F-12
<PAGE>
                        GLOBAL PHARMACEUTICAL CORPORATION

                    NOTES TO FINANCIAL STATEMENTS (continued)

     The Company has the option to redeem outstanding shares of the Preferred
Stock by paying the liquidation value for each share, provided that the closing
sale price of the common stock is seven dollars or more per share in the case of
Series C Preferred Stock and at least five times the conversion price, in the
case of Series D Preferred Stock, for a consecutive twenty day trading period.
Each holder of Preferred Stock shall be entitled to redeem any or all shares in
the event that the Company breaches or fails to comply with its obligations
under the respective Certificates of Designations or the Stock Purchase
Agreements, to the extent that the breach or failure is material to or had a
material adverse effect on the Company, and is not cured within thirty days.

11.   Stockholders' Equity (Deficit)

   Preferred Stock

     The Company authorized 2,000,000 shares of Preferred Stock, $.01 par value
per share (the "Preferred Stock"). The Company issued 72,350 shares of Preferred
Stock of which 65,535 are outstanding and are classified as Mandatorily
Redeemable Preferred Stock at December 31, 1998. (Note 10)

  Common Stock

     In 1995, the Company completed its IPO in which 1,650,000 shares of common
stock were sold for net proceeds to the Company of $11,488,000. In connection
with the IPO, the underwriter received an option to purchase up to 247,500
shares of common stock at $8.50 per share. The underwriter exercised this option
in January 1996, at which time the Company sold 247,500 shares of common stock
for net proceeds of $1,835,000.

     During 1998, 2,070 shares of Series A Preferred Stock and 6,745 shares of
Series B Preferred Stock were converted into 90,544 shares and 278,682 shares of
common stock, respectively. The conversion price ranged from $2.00 to $2.75 per
share. Through March 2, 1999, the remaining 11,280 and 43,255 shares of Series A
and Series B Preferred Stock were converted to common stock (Note 14).

12.  Stock Options

         The Company's 1995 Stock Incentive Plan was adopted by the Company's
Board of Directors for the purpose of securing for the Company and its
stockholders the benefits arising from the ownership of Company stock options by
non-employee directors and key employees who are expected to contribute to the
Company's future growth and success.

         Effective December 1997, the Company's Board of Directors approved the
repricing of 426,800 outstanding options to $3.125 per share, the market value
of common stock on that date. As a result, all outstanding options were
effectively rescinded and reissued at an exercise price of $3.125 per share.
Options vest over a three to four year period and have a maximum term of ten
years. The weighted average fair value of options granted during 1998, 1997 and
1996 was $2.15, $2.03 and $3.37, respectively. The fair value of each option was
estimated on the date of grant using the Black-Scholes option-pricing model with
the following assumptions: (i) no expected dividend yield in 1998, 1997 and
1996, (ii) expected stock price volatility of 72.36%, 50% and 30% in 1998, 1997
and 1996 respectively, (iii) weighted average risk free interest rate of 5.33%,
5.89% and 6% in 1998, 1997 and 1996, respectively, and (iv) expected life of
options of five years in 1998, 1997 and 1996.

                                      F-13
<PAGE>
                        GLOBAL PHARMACEUTICAL CORPORATION

                    NOTES TO FINANCIAL STATEMENTS (continued)

Stock option transactions were:
<TABLE>
<CAPTION>

                                                          1998                       1997                         1996
                                                -----------------------    -----------------------      -----------------------
                                                              Weighted                    Weighted                    Weighted
                                                              Average                      Average                    Average
                                                              Exercise                    Exercise                    Exercise
                                                 Shares        Price         Shares         Price        Shares        Price
                                                --------      --------     ---------      --------      ---------     ---------
<S>                                            <C>             <C>         <C>             <C>          <C>            <C>  
Options outstanding at January 1 ............   436,800         $3.13       297,700         $8.53        236,000        $8.07
Granted .....................................   225,563         $3.50       159,700         $7.42        111,700        $8.87
Canceled ....................................   (26,366)        $3.27       (20,600)        $8.64        (50,000)       $7.13
Rescinded ...................................        --         $  --      (426,800)        $8.23             --        $  --
Reissued ....................................        --         $  --       426,800         $3.13             --        $  --
Options outstanding at December 31 ..........   635,997         $3.26       436,800         $3.13        297,700        $8.53
Options exercisable at December 31 ..........   351,617                     188,016                       75,306
Options available for grant at December 31 ..   114,003                     113,200                      252,300
</TABLE>

         Had compensation cost for the Company's 1998, 1997 and 1996 grants for
stock-based compensation plans been recognized under the provisions of SFAS 123,
the Company's net loss, and net loss per common share for 1998, 1997 and 1996
would approximate the pro forma amounts below (in thousands, except for per
share data):
<TABLE>
<CAPTION>

                                      For the Year Ended               For the Year Ended               For the Year Ended
                                      December 31, 1998                December 31, 1997                 December 31, 1996
                                  --------------------------      ---------------------------       ---------------------------
                                  As Reported      Pro Forma      As Reported       Pro Forma       As Reported       Pro Forma
                                  -----------      ---------      -----------       ---------       -----------       ---------
<S>                                 <C>             <C>             <C>             <C>              <C>               <C>     
Net loss .....................      ($4,755)        ($5,474)        ($8,424)        ($8,871)         ($4,608)          ($4,817)
Net loss per common share ....      ($ 1.07)        ($ 1.22)        ($ 1.97)        ($ 2.07)         ($ 1.08)          ($ 1.13)
</TABLE>
                                                                              
         The pro forma results may not be representative of the effect on
reported operations for future years.

         At December 31, 1998, 635,997 options are outstanding with an exercise
price of $3.26, and a weighted average remaining contractual life of 7.58 years.

13.   Commitments and Contingencies

   Richlyn Order

     The Company is in compliance with a May 25, 1993 order, which was entered
by the United States District Court for the Eastern District of Pennsylvania
(the "Richlyn Order"). The Richlyn Order, among other things, permanently
enjoined Richlyn from introducing into commerce any drug manufactured,
processed, packed or labeled at its manufacturing facility unless it met certain
stipulated conditions. The Company, as a purchaser of the Richlyn facility,
remains obligated by the terms of the Richlyn Order.

                                      F-14

<PAGE>
                        GLOBAL PHARMACEUTICAL CORPORATION

                    NOTES TO FINANCIAL STATEMENTS (continued)

   Product liability and insurance

         The Company assumed the liabilities of Richlyn in connection with
Diethyl Stilbestrol ("DES"), which was manufactured by Richlyn during the late
1950's and early 1960's. DES was prescribed to pregnant women during that period
and has been alleged to cause birth defects. There have been numerous claims
brought against drug manufacturers in connection with DES. Since 1987, Richlyn's
insurers have paid approximately $136,000 on Richlyn's and the Company's behalf
to settle approximately 143 DES-related suits. While Richlyn's insurers have in
the past defended those DES claims against Richlyn and paid all settlements in
connection therewith to date, the insurers have reserved their right to
discontinue the defense of the claims and the payment of settlements at any
time. Claims settlements to date have been based upon market share, and
Richlyn's share of the market during the periods in question was less than 1%.
While there can be no assurance as to the ultimate resolution of these matters,
in the opinion of Management, the ultimate liabilities resulting from such
lawsuits and claims will not materially adversely affect the financial position,
operating results or cash flow of the Company.

   Eurand America Agreement

         The Company is committed to payments of $100,000 for the development
and supply of product batches necessary for clinical studies under the license
and supply agreement entered into with Eurand America in 1997 to develop a
gastro-protected pancrelipase product, subject to Eurand's performance in
accordance with terms and conditions of the agreement. Annual minimum royalty
payments will also become payable upon shipment of the product. The Company has
$100,000 and $41,000 accrued for milestone payments and royalty payments,
respectively, at December 31, 1998.

14.      Subsequent Events

         From January 1, 1999 through March 2, 1999, 11,280 and 43,255 shares of
Series A and Series B Preferred Stock with liquidation values of $1,128,000 and
$4,326,000, respectively, were converted into 2,598,000 shares of Common Stock
at conversion prices ranging from $2.00 to $2.24 per share.

         On March 2, 1999, the Company issued 30,000 shares of Mandatorily
Redeemable Convertible Series D Preferred Stock and a five year warrant to
purchase 375,000 shares of common stock at an initial exercise price equal to
$4.00 per share for aggregate proceeds of $3,000,000. The Company has determined
the fair value of the warrants as being $322,500, using the Black-Scholes option
pricing model, and the fair value of the Preferred Stock as being $2,677,500. In
the first quarter of fiscal 1999, the Company will recognize a $322,500
Preferred Stock dividend to reflect the Series D Preferred Stock at its
liquidation value. An additional $2,000,000 of its Series D Preferred Stock is
expected to be issued to the same investors prior to June 30, 1999 subject to
the Company's stockholders authorization of additional shares of common stock.

          At the option of the holder, each share of Series D Preferred Stock is
convertible into that number of shares of the Company's common stock as is
determined by dividing the liquidation value by the conversion price. The
conversion price is the lower of $2.00 per share or $1.20 per share if the
second closing of Series D Preferred Stock does not occur by June 30, 1999. The
difference between the conversion price and the market value of the common stock
on the date of the issuance of Preferred Stock will be recognized as a
Preferred Stock dividend of $281,000 in the first quarter of fiscal 1999. In
the event the Company, within eighteen months from the Series D initial closing,
issues and sells not less than an aggregate of $1 million of additional shares
of common stock (or securities convertible into common stock) for a
consideration per share of less than $2.00, the conversion price will be reduced
to a price equal to the consideration per share for which additional shares are
sold.

          At the option of the investors, the Company will pay liquidation value
to the investors if the following occur: 1) a sale of all or substantially all
of the Company's operating assets, 2) the Company becomes insolvent, 3) the
Company goes private, or 4) a business combination involving the Company in
which the shareholders of the Company cease to own 50% of the voting power of
all classes of stock or 50% of the total equity securities in the new entity.
Subject to certain specified exceptions, the holders of Series D Preferred Stock
have the preemptive right to maintain current ownership of the Company in future
equity offerings.

                                      F-15

<TABLE> <S> <C>

<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE
CONSOLIDATED BALANCE SHEET AND THE CONSOLIDATED STATEMENT OF INCOME FOR THE
TWELVE MONTHS ENDED DECEMBER 31, 1998 AND IS QUALIFIED IN ITS ENTIRETY BY
REFERENCE TO SUCH FINANCIAL STATEMENTS.
</LEGEND>
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          DEC-31-1998
<PERIOD-START>                             JAN-01-1998
<PERIOD-END>                               DEC-31-1998
<CASH>                                           1,304
<SECURITIES>                                         0
<RECEIVABLES>                                    1,103
<ALLOWANCES>                                        15
<INVENTORY>                                        763
<CURRENT-ASSETS>                                 3,206
<PP&E>                                           5,569
<DEPRECIATION>                                   1,515
<TOTAL-ASSETS>                                   8,853
<CURRENT-LIABILITIES>                            2,911
<BONDS>                                              0
                            6,354
                                          0
<COMMON>                                            47
<OTHER-SE>                                     (2,426)
<TOTAL-LIABILITY-AND-EQUITY>                     8,853
<SALES>                                          4,401
<TOTAL-REVENUES>                                 4,401
<CGS>                                            4,681
<TOTAL-COSTS>                                    4,681
<OTHER-EXPENSES>                                 4,766
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                 113
<INCOME-PRETAX>                                (4,755)
<INCOME-TAX>                                         0
<INCOME-CONTINUING>                                  0
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                   (4,755)
<EPS-PRIMARY>                                   (1.07)
<EPS-DILUTED>                                   (1.07)
        



</TABLE>


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