DAOU SYSTEMS INC
S-3, 1999-09-14
RETAIL STORES, NEC
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     AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 14, 1999
                                         REGISTRATION STATEMENT NO. 333-_______
- -------------------------------------------------------------------------------

                  UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                              Washington, D.C.  20549

                                -------------------

                                      FORM S-3
                               REGISTRATION STATEMENT
                          UNDER THE SECURITIES ACT OF 1933

                                -------------------

                                 DAOU SYSTEMS, INC.
               (Exact name of registrant as specified in its charter)

                                      Delaware
           (State or other jurisdiction of incorporation or organization)

                                     33-0284454
                        (I.R.S. Employer Identification No.)

                                5120 Shoreham Place
                            San Diego, California 92122
                                   (619) 452-2221
    (Address, including zip code, and telephone number, including area code, of
                     registrant's principal executive offices)

                                -------------------

                                  Larry D. Grandia
                       President and Chief Executive Officer
                                 DAOU Systems, Inc.
                                5120 Shoreham Place
                            San Diego, California 92122
                                   (619) 452-2221
(Name, address, including zip code, and telephone number, including area code,
                               of agent for service)

                                -------------------

                                     Copies to:
                               John J. Hentrich, Esq.
                                  Baker & McKenzie
                           101 West Broadway, Suite 1200
                                San Diego, CA  92101

                                -------------------

Approximate date of commencement of proposed sale to the public: As soon as
practicable after this Registration Statement becomes effective. If the only
securities being registered on this Form are being offered pursuant to
dividend or interest reinvestment plans, please check the following box:  / /
If any of the securities being registered on this Form are to be offered on a
delayed or continuous basis pursuant to Rule 415 under the Securities Act of
1933, other than securities offered only in connection with dividend or
interest reinvestment plans, check the following box:  /X/

If this Form is filed to register additional securities for an offering
pursuant to Rule 462(b) under the Securities Act of 1933, please check the
following box and list the Securities Act registration statement number of
the earlier effective registration statement for the same offering:  / /

If this Form is a post-effective amendment filed pursuant to Rule 462(c)
under the Securities Act of 1933, check the following box and list the
Securities Act registration statement number of the earlier effective
registration statement for the same offering:  / /

If delivery of the prospectus is expected to be made pursuant to Rule 434,
please check the following box:  / /

                                -------------------

                           CALCULATION OF REGISTRATION FEE
- -------------------------------------------------------------------------------
TITLE OF EACH       AMOUNT      PROPOSED MAXIMUM     PROPOSED        AMOUNT
  CLASS OF            TO           OFFERING           MAXIMUM          OF
 SECURITIES           BE           PRICE PER         AGGREGATE     REGISTRATION
TO BE REGISTERED  REGISTERED(1)     SHARE(2)       OFFERING PRICE      FEE
- -------------------------------------------------------------------------------
Common Stock,
  $0.001 par
  value per
  share  . . . .  2,750,000           $4.91          $13,502,500     $3,753.70
- -------------------------------------------------------------------------------

(1)  Represents shares of Common Stock which may be offered pursuant to this
     Registration Statement consisting of an estimated 2,750,000 shares
     issuable upon conversion of 2,181,818 shares of Series A Convertible
     Preferred Stock.  For purposes of determining the number of shares of
     Common Stock to be included in this Registration Statement, the Company
     estimated the number of shares of Common Stock issuable in connection
     with the conversion of the Series A Convertible Preferred Stock, based
     on the current conversion price of $5.50, and shares which may be issued
     as dividends or upon the occurrence of any future stock splits,
     anti-dilution events or similar transactions.

(2)  Estimated solely for the purpose of calculating the registration fee
     pursuant to Rule 457(c) of the Securities Act of 1933.  Pursuant to
     Rule 457(c), the maximum offering price per share is $4.91, the average
     of the high and low prices of a share of the Registrant's common stock
     as reported on the Nasdaq National Market System on September 9, 1999,
     and the maximum aggregate offering price of $13,502,500 is the product
     of $4.91 and the number of shares of the Registrant's common stock
     being registered hereby.

THE REGISTRANT HEREBY AMENDS THIS REGISTRATION STATEMENT ON SUCH DATE OR
DATES AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE DATE UNTIL THE REGISTRANT
WILL FILE A FURTHER AMENDMENT WHICH SPECIFICALLY STATES THAT THIS
REGISTRATION STATEMENT WILL THEREAFTER BECOME EFFECTIVE IN ACCORDANCE WITH
SECTION 8(a) OF THE SECURITIES ACT OF 1933, OR UNTIL THE REGISTRATION
STATEMENT WILL BECOME EFFECTIVE ON SUCH DATE AS THE SEC, ACTING PURSUANT TO
SAID SECTION 8(a), MAY DETERMINE.

                                -------------------
<PAGE>

INFORMATION CONTAINED IN THIS PROSPECTUS IS NOT COMPLETE AND MAY BE CHANGED.
THESE SECURITIES MAY NOT BE SOLD UNTIL THE REGISTRATION STATEMENT FILED WITH THE
SECURITIES AND EXCHANGE COMMISSION IS EFFECTIVE.  THIS PROSPECTUS IS NOT AN
OFFER TO SELL THESE SECURITIES AND IT IS NOT SOLICITING AN OFFER TO BUY THESE
SECURITIES IN ANY STATE WHERE THE OFFER OR SALE IS NOT PERMITTED.


                  SUBJECT TO COMPLETION, DATED SEPTEMBER 14, 1999

                                     PROSPECTUS


                                 DAOU SYSTEMS, INC.

                                 2,750,000 SHARES
                                         OF
                      Common Stock, $0.001 Par Value Per Share

                                -------------------

     We are registering for resale up to 2,750,000 shares of our common stock,
par value $0.001 per share, on behalf of the following selling stockholders:
Galen Partners III, L.P.; Galen Partners International III, L.P.; and Galen
Employee Fund III, L.P.

     We will issue the shares of common stock registered by this prospectus upon
the selling stockholders' future conversion of up to 2,181,818 shares of series
A convertible preferred stock, $0.001 par value per share.  The selling
stockholders purchased these shares of series A convertible preferred stock by
entering into a stock purchase agreement, dated as of July 26, 1999, with our
company.

     The selling stockholders may sell all or a portion of the shares of common
stock after conversion from time to time in the open market, in negotiated
transactions or otherwise, and at prices to be determined by the prevailing
market price for the shares or in negotiated transactions.  We do not know when
the selling stockholders will sell their shares of common stock after
conversion, and we will not receive any of the proceeds from their sale.

     Our common stock trades on the Nasdaq National Market under the symbol
"DAOU."  On September 9, 1999, the closing sale price of our common stock as
quoted on the Nasdaq National Market was $4.875 per share.


     INVESTING IN OUR COMMON STOCK INVOLVES SEVERAL RISKS.  SEE "RISK FACTORS"
BEGINNING ON PAGE 4.

     NEITHER THE SECURITIES AND EXCHANGE COMMISSION NOR ANY STATE SECURITIES
COMMISSION HAS APPROVED OR DISAPPROVED OF THESE SECURITIES OR PASSED UPON THE
ADEQUACY OR ACCURACY OF THIS PROSPECTUS.  ANY REPRESENTATION TO THE CONTRARY
IS A CRIMINAL OFFENSE.

                                -------------------

                                October      , 1999

                                         1

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                                 DAOU SYSTEMS, INC.

                                 TABLE OF CONTENTS

SUMMARY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  3

THE COMPANY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  3

RISK FACTORS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .  4

FORWARD LOOKING STATEMENTS . . . . . . . . . . . . . . . . . . . . . . . 11

REFERENCE DATA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11

DESCRIPTION OF SECURITIES. . . . . . . . . . . . . . . . . . . . . . . . 11

USE OF PROCEEDS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12

SELLING STOCKHOLDERS . . . . . . . . . . . . . . . . . . . . . . . . . . 13

PLAN OF DISTRIBUTION . . . . . . . . . . . . . . . . . . . . . . . . . . 14

LEGAL MATTERS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16

EXPERTS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16

WHERE YOU CAN OBTAIN MORE INFORMATION. . . . . . . . . . . . . . . . . . 16


     You should rely only on the information contained or incorporated by
reference in this prospectus and in any prospectus supplement.  No one has been
authorized to provide you with different information.

     You should not assume that the information in this prospectus or any
prospectus supplement is accurate as of any date other than the date provided on
the front page of the documents.

                                         2
<PAGE>

                                      SUMMARY

     On behalf of the selling stockholders listed in this prospectus, we are
registering for resale 2,750,000 shares of our common stock issuable upon the
conversion of up to 2,181,818 shares of series A convertible preferred stock,
$0.001 par value per share.

     You should read the following information about our company, together with
the more detailed information about the shares of common stock covered by this
prospectus, contained elsewhere in this prospectus.  In particular, you should
read the section entitled "Risk Factors," which explains that your investment in
shares of our common stock involves a high degree of risk.  Our financial
statements and related notes are not included in this prospectus, but are
incorporated by reference in the exhibits located at the end of this prospectus.

                                  THE COMPANY

     We provide integrated information technology solutions and services to the
United States healthcare industry.  Our capabilities range from up-front
strategic consulting to information technology system design, implementation and
long-term tactical support.  Our information technology service capabilities
include:

- -    SOFTWARE APPLICATION IMPLEMENTATION.  We supply staffing resources to
     hospitals and other healthcare organizations to assist with the planning
     and implementation of healthcare software applications.  Our software
     application consultants are vendor certified and can install nearly
     90% of the most common healthcare software applications.


- -    COMMUNICATIONS INFRASTRUCTURE.  We deliver services relating to the
     information superstructure in healthcare enterprises, including networking,
     Intranet, Internet, desktop and voice, video and data solutions. These
     service offerings include assessment, design, implementation, management
     and outsourcing.


- -    MANAGEMENT CONSULTING.  We develop business plans and provide guidance on
     information technology solutions for healthcare providers and managed
     care organizations.

- -    INTEGRATION SERVICES.  We analyze, implement and support information
     systems that are designed to meet a customer's business objectives, reduce
     cost and improve the quality of care. Our services include system
     interfaces, the creation and management of data repositories and the
     development of specific software tools.


     We originally incorporated our company in California on July 16, 1987 under
the name DAOU Systems, Inc., and reincorporated it in Delaware on November 15,
1996.  Our principal executive offices are located at 5120 Shoreham Place, San
Diego, California  92122.  Our telephone number is (619) 452-2221 and our
facsimile number is (619) 452-1338.  Our e-mail address is [email protected] and our
home page address is http://www.daou.com.

     For additional information relating to our business, operations, properties
and other matters, see the documents referred to below under "Incorporation of
Certain Information by Reference."
                                         3

<PAGE>

                                    RISK FACTORS

WE MAY NOT MANAGE SUCCESSFULLY OUR BUSINESS OPERATIONS IF WE FAIL TO HIRE, TRAIN
AND RETAIN QUALIFIED COMPUTER NETWORK ENGINEERS, SOFTWARE APPLICATION
CONSULTANTS AND KEY MANAGEMENT EMPLOYEES.

     Our business strategy depends in large part on the services of our key
management and technical personnel such as computer network engineers and
software application consultants.  These personnel are in short supply, and
the competition for their services is intense.  This shortage is especially
true for senior network engineers and software application consultants who
have experience in and understand the hospitals, integrated healthcare
delivery networks and other healthcare provider organizations that we serve.
Our business also requires that our employees learn and implement the latest
technical applications and innovations for our customers.  In addition, we
have experienced significant turnover among our technical personnel due in
part to the significant time and travel demands and increased competition for
their services. Any inability to hire, train and retain a sufficient number
of qualified computer network engineers and software application consultants
could impair our ability to adequately manage and complete our existing
projects or to obtain new customers and projects.  Our failure to retain key
personnel or to attract additional qualified employees could materially and
adversely affect our ability to deliver services to our customers in a timely
and effective manner, if at all.

     In addition, during this calendar year, we have experienced turnover in
our senior management. In March 1999, we appointed Larry Grandia to serve as
our President, replacing Daniel Daou; and, in June 1999, we appointed Mr.
Grandia as our Chief Executive Officer, replacing Georges Daou.  In addition,
we recently replaced our Chief Financial Officer, who left our employ on
August 31, 1999; and we recently reassigned our Chief Operating Officer to
other duties.  In early 1999, we also transitioned our Vice President of
Human Resources to other duties.  This transition of management personnel may
adversely affect our operating performance, given the diversion of
management's attention from operational to recruitment activities and the
time required for new senior personnel to assimilate and manage effectively
our business operations.

MANY FACTORS HAVE CAUSED AND WILL CONTINUE TO CAUSE OUR FINANCIAL RESULTS TO
FLUCTUATE.

     We have experienced significant quarterly fluctuations in our operating
results mainly due to our recent acquisitions and efforts to expand our
business.  Variations in our revenues and operating results may continue from
time to time, due to various factors, including:

     -    the failure to achieve a successful sales program and to secure and
          deliver new customer contracts at the budgeted rate;

     -    industry spending patterns and market conditions that may affect
          adversely the buying decisions of our current and prospective
          customers, such as the uncertain level of spending on information
          technology before and after the year 2000 conversion, the continued
          consolidation among healthcare provider entities and the projected
          reduction in reimbursements available to healthcare providers;

     -    the relatively longer sales cycle in obtaining new customers and
          larger contracts;

     -    the timing and extent of employee training or the loss of key
          employees;

     -    competition;

     -    the reduction in size, delay in commencement, interruption or
          termination of one or more significant projects;

     -    the loss or termination of preferred partnership relationships with
          software vendors or hospital groups;

                                         4
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     -    the failure to estimate accurately the resources required to complete
          new or ongoing projects, including increased labor costs due to delays
          in project delivery schedules;

     -    the commencement or completion during a quarter of one or more
          significant projects;

     -    variations in the product or professional service content of our
          projects;

     -    the development and introduction of new services;

     -    the continued effect of acquisitions, including additional
          administrative staffing and other increased infrastructure
          requirements to integrate the newly acquired companies; and

     -    the effect of negative publicity relating to our litigation
          and operations.

     Although our revenues fluctuate from quarter to quarter, the substantial
majority of our operating expenses, particularly personnel and related costs,
depreciation and rent, are relatively fixed.  We expect these costs to
increase in the future as we intend to grow our business and correspondingly
expand our resources, such as additional computer network engineers, software
application consultants and other employees and new offices, systems and
other infrastructure. Accordingly, a variation in the timing of the
commencement or completion of customer projects or contracts, particularly at
or near the end of any quarter, may cause significant variations in operating
results from quarter to quarter and could result in losses for a particular
quarter.  In addition, an unanticipated delay or termination of a major
project or contract, or a series of smaller projects or contracts, could
require us to maintain or terminate under-utilized employees, which could
result in higher than expected expenses during a quarter.

OUR CASH RESERVES AND LIQUIDITY WOULD BE IMPACTED SEVERELY IF THE HOLDERS OF
OUR SERIES A CONVERTIBLE PREFERRED STOCK REQUIRE US TO REDEEM THEIR SHARES
FOR CASH UPON THE OCCURRENCE OF SPECIFIED EVENTS.

     We will have to pay a minimum of $12,000,000 in cash if the holders of
all 2,181,818 shares of currently outstanding series A convertible preferred
stock require us to redeem their shares upon the occurrence of any of the
following events:

     -    Larry D. Grandia's resignation as Chief Executive Officer of our
          company;

     -    our failure to hire a replacement Chief Executive Officer within 180
          days following Mr. Grandia's termination as Chief Executive Officer;
          or

     -    the failure of Georges J. Daou or Daniel J. Daou to vote for a
          liquidation, dissolution or a transaction involving a consolidation,
          merger, sale of all or substantially all of our assets or disposition
          of more than 50% of the voting power of our company, if our board of
          directors votes in favor of the above-described transactions.

     We will have to redeem for cash any or all of the shares of series A
convertible preferred stock if the holders of a majority of the then
outstanding shares of series A convertible preferred stock provide us with
written notice within 30 days of the occurrence of any of the above events. If
we receive a written redemption notice, then we will have to pay a cash amount
of $5.50, plus any accrued but unpaid dividends, for each share of series A
convertible preferred stock covered under the redemption notice. We cannot
assure you that we will have enough cash reserves to satisfy the redemption of
any or all of the then outstanding shares of series A convertible preferred
stock.

WE MAY EXPERIENCE DISRUPTIONS IN OUR BUSINESS OPERATIONS AND INCREASED EXPENSES
IF WE DO NOT MANAGE EFFECTIVELY OUR RECENT GROWTH AND ACQUISITIONS.

     Our revenue growth and acquisitions during the last few years have placed
significant demands on our management, operational, technical, financial and
other systems and resources.  This growth has:

     -    increased our working capital funding requirements;

     -    caused us to expand our efforts to recruit qualified personnel;

     -    forced us to expand our operational capacity; and

     -    resulted in new and increased responsibilities for management
          personnel.

     During 1997 and 1998, we acquired 11 companies through pooling-of-interests
mergers.  We continue to face significant challenges and risks relating to these
acquisitions, including the standardization of diverse management information
and accounting systems and the training and retention of employees who work at
various company and customer sites throughout the United States.  To more
effectively manage our various business divisions, we are implementing new
enterprise resource planning software that is designed to coordinate accounting,
scheduling, utilization management, purchasing and other management functions.
We expect to complete our transition to the new software by the second quarter
of 2000.  However, this software may not adequately integrate the operations of
our business divisions; and we may experience disruptions in our operations
during the transition to the new software.

     We must continue to improve our operational, financial and internal
systems to accommodate the increased number of projects and customers and the
increased size of our operations, workforce and facilities.  In addition, we
continue to analyze and determine which processes and functions require
standardization across the company, such as common billing, collection and
contract procedures, and which functions are better managed independently by
the operating divisions. We cannot assure you that we will address
successfully the demands caused by our recent growth and acquisitions.

                                       5
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THE CONSOLIDATION AND CHANGING REGULATORY ENVIRONMENT OF THE HEALTHCARE INDUSTRY
MAY REDUCE THE SIZE OF OUR TARGET CUSTOMER MARKET AND RESULT IN THE TERMINATION
OF CUSTOMER CONTRACTS.

     We receive substantially all of our revenues from customers involved in
the healthcare industry.  Consequently, our business is vulnerable to
changing conditions affecting this industry.  Many healthcare provider
organizations are consolidating to create larger organizations with greater
regional market power and are forming affiliations for purchasing products
and services.  This consolidation could reduce our target market and result
in the termination of customer contracts.  In particular, some of our
customers have scaled back or terminated their relationship with us following
their acquisition, and this trend may continue in the future.  For example,
in 1997, Candler Health System, a large information systems outsourcing
customer located in Savannah, Georgia that accounted for 6% of our revenues
in 1996, terminated its information systems outsourcing contract with us
after it consolidated with another healthcare enterprise.  Moreover,
consolidated enterprises or affiliated enterprises may try to use their
greater bargaining power to negotiate reductions in the amounts paid to us
for our services.  Any reduction in the size of our target market or failure
to maintain adequate price levels could materially and adversely affect our
revenues and financial condition.

     The healthcare industry also is subject to changing political, economic and
regulatory influences that may affect the procurement practices and operations
of participants in the healthcare industry.  For example, recent federal
legislation may reduce the reimbursements available for hospitals.  Reduced
reimbursements may negatively impact the spending patterns and demand for our
information technology services.  We cannot predict with any certainty what
impact these developments could have on our business.


OUR BUSINESS MAY BE SEVERELY DISRUPTED AND OUR REVENUES MAY DECLINE IF WE OR OUR
KEY SUPPLIERS AND CUSTOMERS FAIL TO BE YEAR 2000 COMPLIANT.

     We use a significant number of computer equipment, software and devices
with embedded technology in our internal operations and in providing services
and reselling products to customers.  To the extent that these systems are
unable to interpret appropriately the upcoming calendar year 2000, we may be
exposed to the following risks:

     -    service delays to our customers arising from the failure of vendors,
          manufacturers and service providers to adequately address year 2000
          issues;

     -    increased warranty and other claims by our customers and/or
          increased product and system repair, replacement, service and
          maintenance obligations;

     -    diversion of resources to address and/or remediate year 2000 issues;
          and

     -    our inability to properly staff our geographically dispersed customer
          sites during the year 2000 conversion.

     We have not yet completed our review of the year 2000 compliance of our
internal computer equipment, software and devices with embedded technology.  If
any of these systems experience year 2000 compliance problems, we may be unable
to process transactions, send invoices or conduct communications.  In addition,
based on our ongoing review of our customer contracts, we estimate that
approximately 20% of our customer contracts have no specific liability
limitations relating to year 2000 issues, which could increase our exposure to
year 2000 claims.  We also could be exposed to liabilities from agreements
entered into by our subsidiaries, including agreements that our acquired company
subsidiaries entered into before our acquisition.  Furthermore, we have
identified one major sales, service

                                    6
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and maintenance contract that requires us to modify, repair or replace
third-party products that are not year 2000 compliant. If the costs to ensure
that these products are compliant are significant and if we are unable to
obtain adequate indemnification and/or warranty coverage from the vendor,
manufacturer or service provider, then these costs may materially and
adversely affect our financial condition.

     In addition, our customers' failure to be year 2000 compliant may
materially and adversely affect our ability to obtain new contracts or
receive payments from these customers.  If our customers or potential
customers delay purchases of information systems until they have resolved
their concerns regarding year 2000 compliance, then any revenues may be
severely impacted.  In addition, if our customers devote significant
resources to make their information systems year 2000 compliant, then they
may have to reduce their expenditures on our services.

INTENSE COMPETITION IN OUR INDUSTRY FROM COMPETITORS WITH GREATER FINANCIAL,
TECHNICAL AND MARKETING RESOURCES COULD PREVENT US FROM INCREASING REVENUES
AND ACHIEVING OR SUSTAINING PROFITABILITY.

     The industry for healthcare information technology services has a large
number of participants and is subject to rapid change and intense
competition. In addition, many of our competitors have significantly greater
financial, technical and marketing resources and greater name recognition
than we do.  We currently compete against:

     -    consulting firms such as First Consulting Group, Inc. and Superior
          Consulting Holdings Corporation and the consulting divisions of the
          major accounting firms;

     -    healthcare information technology companies such as McKesson HBOC and
          Shared Medical Systems Corporation;

     -    system integrators such as Science Applications International
          Corporation, Electronic Data Systems Corporation and Perot Systems
          Corporation; and

     -    telecommunications providers and network equipment vendors.

     We also compete with smaller regional network services firms in selected
geographical areas of the country.  In addition, we have faced, and expect to
continue to face, additional competition from new entrants into our markets,
such as other healthcare information technology companies not presently
offering or emphasizing network systems services and large network services
companies not currently focusing on healthcare.  Increased competition could
result in price reductions, fewer customer projects, under-utilization of
employees, reduced operating margins and loss of market share, any of which
could materially and adversely affect our business, financial condition and
results of operations. We cannot assure you that we will compete successfully
against current and future competitors.

WE MAY BE SUED IF OUR COMPUTER NETWORK SYSTEMS FAIL TO PROVIDE ACCURATE,
RELIABLE AND TIMELY INFORMATION TO HEALTHCARE PROVIDERS.

     Our computer network systems are designed to provide access to and
accurate delivery of a wide range of information within a healthcare provider
organization, including information used by clinicians in the diagnosis and
treatment of patients.  If a computer network system that we installed or
maintain fails to provide accurate, reliable and timely information to a
patient's healthcare provider, and, as a result, that patient is injured,
then either the patient or the healthcare provider might bring a claim
against us based on our installation or management of the computer network
system.  In addition, we may be sued if a patient is injured because of a
service that we have performed or failed to perform for the healthcare
provider organization. Although we maintain errors and/or omissions
insurance, this insurance coverage

                                      7
<PAGE>

may not adequately cover any claims asserted against us.  In addition,
appropriate insurance may not continue to be available to us in the future at
commercially reasonable rates.

WE DEPEND ON A SMALL NUMBER OF LARGE CUSTOMERS TO PROVIDE A SIGNIFICANT PORTION
OF OUR REVENUES.

     We receive a significant portion of our revenues from a relatively
limited number of large customer contracts, and expect this pattern to
continue in the future.  As a percentage of total revenues, our five largest
customers accounted for approximately:

     -    26% for the six months ended June 30, 1999;
     -    19% for the year ended December 31, 1998;
     -    22% for the year ended December 31, 1997; and
     -    27% for the year ended December 31, 1996.

     The loss of any large customer could materially and adversely affect our
revenues and financial condition.  In particular, three of our large
information technology outsourcing customers represented approximately 15% of
total revenues during the six months ended June 30, 1999.  If we lose one of
these outsourcing customers, then we will face significant challenges in
finding other engagements on which to staff these employees.  Delays in
reassigning and the resulting under-utilization of these employees would
impact negatively our operating results and financial condition.

OUR CUSTOMERS CAN TERMINATE, WITHOUT PENALTY, SOME OF OUR FIXED PRICE AND
OUTSOURCING CONTRACTS.

     Although we enter into multi-year contracts with many of our customers,
some of our fixed price and outsourcing customers can reduce or cancel their
use of our services before the end of the contract term.  For example, Saint
Mary's Health Network, a large information technology services customer
located in Reno, Nevada that accounted for 9% of our revenues during the six
months ended June 30, 1999, may terminate our information management
agreement on 90 days' written notice without penalty.  In addition, we have
provided and expect to continue providing services to customers without
long-term contracts.  When a customer defers, modifies or cancels a project,
we must rapidly redeploy our technical and other personnel to other projects
to minimize the under-utilization of employees and the resulting adverse
impact on our operating results.  Furthermore, our operating expenses are
relatively fixed and cannot be reduced on short notice to compensate for
unanticipated variations in the number or size of projects in progress.  As a
result, any termination, significant reduction or modification of our
business relationships with any significant customers or with a number of
smaller customers could materially and adversely affect our operating
results.

OUR LONG SALES AND PROJECT DELIVERY CYCLES EXPOSE US TO POTENTIAL LOSSES.

     Our sales process for network projects is often subject to delays
associated with the lengthy approval process that typically accompanies
significant capital expenditures by our customers.  During this process, we
expend substantial time, effort and resources marketing our services,
preparing contract proposals and negotiating contracts.  Any failure to
obtain a signed contract and receive payment for our services after expending
significant time, effort and resources could materially and adversely affect
our revenues and financial condition.

                                      8
<PAGE>

FIXED PRICE AND FIXED TIME FRAME CONTRACTS MAY ADVERSELY AFFECT OUR
PROFITABILITY IF WE DO NOT ACCURATELY ESTIMATE THE RESOURCES AND TIME
REQUIRED TO COMPLETE THESE CONTRACTS.

     We offer a portion of our computer network system and consulting
services on a fixed-price, fixed-time frame basis.  Consequently, we bear the
risk of cost over-runs in connection with these projects.  Our failure to
estimate accurately the resources and time required for a project or our
failure to complete our contractual obligations within the committed
fixed-time frame could reduce our profit or cause a loss.  In addition, the
amount of time that it takes to complete a project often depends on factors
outside of our control, including the customer's existing information
technology systems or the customer's lack of resources to devote to the
project.  We might not achieve the profitability and staff utilization that
we expect under our fixed price and fixed time contracts, and may even incur
losses on these contracts in the future.

WE MUST CONTINUALLY OFFER SERVICES AND PRODUCTS THAT MEET OUR CUSTOMERS'
DEMANDS, AS NEW TECHNOLOGIES OR INDUSTRY STANDARDS COULD RENDER OUR SERVICES
OBSOLETE OR UNMARKETABLE.

     We receive a significant portion of our revenues from projects based on
complex computer networks.  The markets for computer network products and
services are continuing to develop and are characterized by rapid change.  We
cannot assure you that products, systems or technologies developed by third
parties will not render one or more of our services noncompetitive or
obsolete. Our success will depend on our ability to offer services and
products that keep pace with continuing changes in technology, evolving
industry standards and the changing preferences of our healthcare customers.
We cannot assure you that we will successfully address these developments.

MANY FACTORS RELATED TO OUR BUSINESS OPERATIONS AND INDUSTRY COULD IMPACT OUR
FUTURE STOCK PRICE, CAUSING WIDE FLUCTUATIONS IN VALUE AND SIGNIFICANT
VOLATILITY.

     Based upon the historical performance of our common stock, we anticipate
that the future price of our common stock may be subject to wide fluctuations
because of announcements of:

     -    quarterly fluctuations in our operating results;

     -    changes in earnings estimates by analysts;

     -    negative publicity relating to our litigation and operations;

     -    strategic relationships or acquisitions;

     -    new customer contracts or services by us or our competitors;

     -    general conditions in the market for computer network services;

     -    healthcare industry and general market conditions; and

     -    changes in our pricing policies or those of our competitors.

     In addition, in recent years, the stock market in general and the shares
of technology companies in particular have experienced extreme price
fluctuations. Fluctuations in the price of our shares of common stock may be
disproportionate or unrelated to our operating performance and may affect
adversely the market price of our common stock.

                                      9
<PAGE>

FUTURE SALES OF OUR COMMON STOCK IN THE PUBLIC MARKET COULD ADVERSELY AFFECT
THE PRICE OF OUR COMMON STOCK AND OUR ABILITY TO RAISE ADDITIONAL EQUITY
CAPITAL.

     The sale of substantial amounts of our common stock in the public
market, the prospect of these sales or the sale or issuance of convertible
securities or warrants could affect adversely the market price of our common
stock.  Of the 17,696,687 shares outstanding as of September 9, 1999,
11,185,012 shares of common stock are freely tradable without
restriction in the public market, unless the shares are held by "affiliates"
of our company as defined in Rule 144 under the Securities Act of 1933, or
are otherwise required to comply with specific sale volume limitations and
other restrictions under Rule 144. The remaining 6,511,675 shares are
"restricted securities" as defined in Rule 144.  This prospectus registers an
additional 2,750,000 shares of common stock that will be freely tradable upon
conversion of the 2,181,818 outstanding shares of series A convertible
preferred stock.  In addition, we have registered on a form S-8 registration
statement an aggregate of 4,000,000 shares of common stock under the DAOU
Systems, Inc. 1996 Stock Option Plan.  As of September 9, 1999, an additional
112,240 shares of common stock were subject to other outstanding stock options.

OUR OFFICERS AND DIRECTORS HAVE THE POWER TO INFLUENCE THE ELECTION OF
DIRECTORS AND THE PASSAGE OF STOCKHOLDER PROPOSALS BECAUSE THEY COLLECTIVELY
HOLD A SUBSTANTIAL NUMBER OF SHARES OF OUR COMMON STOCK.

     As of September 9, 1999, our executive officers, directors and
affiliated persons beneficially owned approximately 44% of the
outstanding shares of common stock.  As a result, these stockholders can
exercise significant influence over all matters requiring stockholder
approval, including the election of directors and approval of significant
corporate transactions.  This concentration of ownership also may delay or
prevent a change in control of our company.

PROVISIONS OF DELAWARE LAW AND OUR CERTIFICATE OF INCORPORATION AND BYLAWS
MAY DETER PREVENT OR DELAY TAKEOVER ATTEMPTS AND A CHANGE OF CONTROL OF OUR
COMPANY.

     A number of provisions of Delaware law and our certificate of
incorporation and bylaws could delay, defer or prevent a change in control of
our company and could limit the price that some investors might be willing to
pay in the future for shares of our common stock.  These provisions:

     -    prohibit us from engaging in any business combination with any
          interested stockholder for a period of three years from the date the
          person became an interested stockholder unless specific conditions are
          met;

     -    permit our board of directors to issue shares of preferred stock
          without stockholder approval on the terms as our board may determine;

     -    provide for a classified board of directors;

     -    eliminate the right of our stockholders to act by written consent
          without a meeting;

     -    require advanced stockholder notice to nominate directors and raise
          matters at the annual stockholders meeting;

     -    eliminate cumulative voting in the election of directors; and

     -    allow for the removal of directors only for cause and with a
          two-thirds vote of our outstanding shares.

                                      10
<PAGE>

                           FORWARD LOOKING STATEMENTS

     This prospectus contains forward-looking statements concerning future
events or performance of our company.  You should not rely excessively on
these forward-looking statements, because they are only predictions based on
our current expectations and assumptions.  Forward-looking statements often
contain words like "estimate," "anticipate," "believe," "expect" or similar
expressions. Many known and unknown risks and uncertainties could cause our
actual results to differ materially from those indicated in these
forward-looking statements.  You should review carefully the risks and
uncertainties identified in this prospectus, including those explained in the
above risk factors and in our other SEC filings such as our Form 10-K/A for
the fiscal year ended December 31, 1998. We have no obligation to update or
announce revisions to any forward-looking statements to reflect actual events
or developments.

                                  REFERENCE DATA

     Industry, market and market share information that may be contained in this
prospectus is based on information appearing in publicly available reports.  We
have not independently verified this information.

                             DESCRIPTION OF SECURITIES

     On July 26, 1999, we entered into a stock purchase agreement with the
selling stockholders listed in this prospectus for the purchase of 2,181,818
shares of series A convertible preferred stock for an aggregate purchase price
of $12 million.  The selling stockholders may convert at any time any or all of
the shares of series A convertible preferred stock that they acquired into
shares of common stock at a conversion rate equal to $5.50 per share, subject to
adjustments for any stock split, stock dividend or other subdivision or a
consolidation of the outstanding common stock.  The conversion rate also will be
adjusted downward if we issue securities at a price less than the adjusted
conversion price that is in effect immediately before the issuance.

     The selling stockholders are entitled to receive dividends on the series A
convertible preferred stock at an annual rate of 6%, based on the issue price of
$5.50 per share, until July 27, 2001.  After July 27, 2001, the holders of
series A convertible preferred stock are entitled to receive dividends at an
annual rate of 6% plus 1% for each successive year after July 27, 2001, based on
the issue price of $5.50 per share.  These dividends are payable semi-annually
in shares of series A convertible preferred stock.  If the payment of these
dividends would cause our company to issue more than 19.9% of our outstanding
shares of common stock at a price below the market value on the date of
issuance, then the dividend will be payable in cash.

     Each of the selling stockholders and their respective affiliates may not
convert, however, a number of shares of series A convertible preferred stock
that would result in beneficial ownership exceeding 3,521,501 shares, which
number equals 19.9% of the total outstanding shares of common stock on July
27, 1999.

     Each share of series A convertible preferred stock will automatically
convert into shares of common stock if the common stock's closing price equals
or exceeds $11.00 per share, as adjusted for any stock split, dividend,
combination or other recapitalization, for 20 consecutive trading days at any
time after July 27, 2000.  Fifty percent (50%) of the series A convertible
preferred stock held by each selling stockholder will automatically convert into
shares of common stock if the common stock's closing


                                      11
<PAGE>

price equals or exceeds $13.75 per share, as adjusted for any stock split,
dividend, combination or other recapitalization, for 20 consecutive trading
days at any time between November 24, 1999 and July 27, 2000.

     We may be required to redeem the series A convertible preferred stock for
cash if the holders of a majority of the outstanding shares of series A
convertible preferred stock provide written notice to us within 30 days of the
occurrence of the following events:

     -    Larry D. Grandia's resignation as Chief Executive Officer of our
          company;

     -    our failure to hire a replacement Chief Executive Officer within 180
          days following Mr. Grandia's termination as Chief Executive Officer;
          or

     -    the failure of Georges J. Daou or Daniel J. Daou to vote for a
          liquidation, dissolution, or a transaction involving a consolidation,
          merger, sale of all or substantially all of our assets or disposition
          of more than 50% of the voting power of our company, if our board of
          directors votes in favor of the above-described transactions.

     Each selling stockholder has the right to one vote for each share of common
stock into which its series A convertible preferred stock may be converted.  The
holders of series A convertible preferred stock have the same voting rights and
powers as any holder of our company's common stock, are entitled to vote on any
question upon which the holders of common stock have the right to vote, and are
entitled to notice of any stockholders' meeting.

     If our company is liquidated or dissolved, then the selling stockholders
will be entitled to receive, before any distribution to holders of our common
stock, $5.50 per share of series A preferred stock plus an amount in cash equal
to any accrued but unpaid dividends.

     Under the related registration rights agreement, we agreed to register the
underlying shares of common stock for resale by the selling stockholders.  We
will prepare and file any amendments and supplements to this registration
statement, as may be necessary to comply with the rules and regulations of the
Securities Act of 1933, to keep it effective until the earlier of:

     -    the date on which each selling stockholder may sell all of its shares
          of common stock registered under this prospectus within any 90 day
          period permitted by the SEC rules, including Rule 144; or
     -    the date on which the selling stockholders have sold all of the shares
          covered by this prospectus.

We have agreed to bear specific expenses, other than broker discounts and
commissions, in connection with this registration statement.

     If the maximum number of shares registered under this prospectus do not
cover all of the shares of common stock issued in connection with the conversion
of the series A convertible preferred stock, then we similarly will register the
excess shares with the SEC.


                               USE OF PROCEEDS

     The shares of common stock registered under this prospectus are registered
solely for the accounts of the selling stockholders.  We will not receive any of
the proceeds from the sale of any of the shares registered under this
prospectus.


                                      12
<PAGE>

                            SELLING STOCKHOLDERS

     The table below lists the selling stockholders and other information
regarding their beneficial ownership of the common stock.  Except as otherwise
disclosed in this prospectus, the selling stockholders neither have nor within
the past three years had any position, office or other material relationship
with our company or any of its predecessors or affiliates.  Because the selling
stockholders may offer all or a portion of the shares of common stock registered
by this prospectus, we cannot estimate the number of shares that will be held by
the selling stockholders after the sales.  In addition, prior to the filing of
this prospectus, the selling stockholders may have sold, transferred or
otherwise disposed of a portion of the shares of common stock registered under
this prospectus in transactions exempt from the registration requirements of the
Securities Act of 1933.  With respect to the shares of common stock issuable
upon conversion of the shares of series A convertible preferred stock, the
number of shares included in this prospectus may be adjusted and could differ
significantly from the estimated amounts listed in the following table because
of factors that we cannot predict on the date of this prospectus.

     We obtained the information provided in the table below from the selling
stockholders.  The selling stockholders may sell all, some or none of their
shares covered by this prospectus.  See "Plan of Distribution."

<TABLE>
<CAPTION>
- ---------------------------------------------------------------------------------------------------------------------------------
- ---------------------------------------------------------------------------------------------------------------------------------
                                                BENEFICIAL OWNERSHIP OF                               BENEFICIAL OWNERSHIP OF
                                                     COMMON STOCK                                        COMMON STOCK AFTER
                                                  PRIOR TO OFFERING (1)                                      OFFERING (1)
                                             ----------------------------   NUMBER OF SHARES OF  --------------------------------
                                                NUMBER OF     PERCENTAGE    COMMON STOCK COVERED     NUMBER OF     PERCENTAGE
NAME OF SELLING STOCKHOLDER                     SHARES(2)    OF CLASS (3)   BY THIS PROSPECTUS(2)    SHARES (4)   OF CLASS (3)
- ---------------------------------------------------------------------------------------------------------------------------------
<S>                                             <C>              <C>        <C>                      <C>          <C>
Galen Partners III, L.P. (5)                    2,512,306        12.4%            2,512,306               0             *

Galen Partners International III, L.P. (6)        227,407         1.3%              227,407               0             *

Galen Employee Fund III, L.P. (7)                  10,288          *                 10,288               0             *

     Total                                      2,750,000        13.4%            2,750,000               0             *
- ---------------------------------------------------------------------------------------------------------------------------------
- ---------------------------------------------------------------------------------------------------------------------------------

     ----------------------------------------------------------------------------------------------------------------------
</TABLE>
*    Less than 1%.

(1)  Beneficial ownership is determined in accordance with the rules of the SEC
     and generally includes voting or investment power with respect to
     securities.  Except as governed by applicable community property laws, the
     selling stockholders have sole voting and investment power with respect to
     the respective shares of common stock owned by them.

(2)  Represents our estimate of the number of shares of common stock issuable in
     connection with the conversion of the series A convertible preferred stock
     based on the current conversion price of $5.50 and shares that may be
     issued as dividends or upon the occurrence of anti-dilution events.

(3)  Based upon 17,696,687 shares of common stock outstanding as of September 9,
     1999.

(4)  Assumes the sale of all of the shares of common stock registered under this
     prospectus to persons who are not affiliates of the selling stockholders.


                                      13
<PAGE>

(5)  Galen Partners III, L.P., a Delaware limited partnership, is affiliated
     with Claudius, LLC, a Delaware limited liability company, which is the
     general partner of this fund.  David Jahns, a director of our company, is a
     member of Claudius, LLC.  Mr. Jahns disclaims beneficial ownership of the
     shares held by this entity, except to the extent of his indirect interest
     in the shares held by this entity arising from his membership interest in
     Claudius, LLC.

(6)  Galen Partners International III, L.P., a Delaware limited partnership, is
     affiliated with Claudius, LLC, which is the general partner of this fund.
     David Jahns, a director of our company, is a member of Claudius, LLC.  Mr.
     Jahns disclaims beneficial ownership of the shares held by this entity,
     except to the extent of his indirect interest in the shares held by this
     entity arising from his membership interest in Claudius, LLC.

(7)  Galen Employee Fund III, L.P., a Delaware limited partnership, is
     affiliated with Galen Associates, a venture capital investment firm and the
     investment manager of this fund.  David Jahns, a director of our company,
     is a Vice President of Galen Associates.  Mr. Jahns disclaims beneficial
     ownership of the shares held by these entities.


                                PLAN OF DISTRIBUTION

     The selling stockholders have advised us that they may offer the shares of
common stock registered under this prospectus to purchasers from time to time:

     -    in transactions in the Nasdaq National Market System, in negotiated
          transactions, or by a combination of these methods;

     -    at fixed prices that may be changed;

     -    at market prices prevailing at the time of the resale;

     -    at prices related to these market prices; or

     -    at negotiated prices.

     At the date of this prospectus, the selling stockholders have not entered
into any underwriting arrangements.  The selling stockholders may sell the
shares registered under this prospectus to or through:

     -    ordinary brokers' transactions;

     -    transactions involving cross or block trades or otherwise on the
          Nasdaq National Market;

     -    purchases by brokers, dealers or underwriters who may receive
          compensation in the form of discounts or commissions from the selling
          stockholders or the purchasers of these shares, for whom the
          broker-dealers may act as agent or principal, or both;

     -    "at the market" to or through market makers or into an existing market
          for our common stock;

     -    in other ways not involving market makers or established trading
          markets, including direct sales to purchasers or sales effected by
          agents;

     -    through transactions in options, swaps or other derivatives (whether
          exchange-listed or otherwise);

     -     in privately negotiated transactions;


                                      14
<PAGE>

     -     to cover short sales; or

     -     any combination of the foregoing.

     From time to time, one or more of the selling stockholders may pledge,
hypothecate or grant a security interest in some or all of the shares of common
stock registered under this prospectus owned by them, and the pledgees, secured
parties or persons to whom these shares have been hypothecated will, upon
foreclosure in the event of default, be deemed to be selling stockholders under
this prospectus.  The number of shares of  common stock registered under this
prospectus and beneficially owned by those selling stockholders who so transfer,
pledge, donate or assign those shares will decrease as and when they take these
actions.  The plan of distribution for shares sold under this prospectus will
otherwise remain unchanged, except that the transferees, pledgees, donees or
other successors will be selling stockholders under this prospectus.  In
addition, a selling stockholder may, from time to time, sell short shares of
common stock.  In these instances, this prospectus may be delivered in
connection with these short sales and the shares of common stock offered hereby
may be used to cover these short sales.

     A selling stockholder may enter into hedging transactions with
broker-dealers and the broker-dealers may engage in short sales of the common
stock in the course of hedging the positions they assume with that selling
stockholder, including, without limitation, in connection with distributions
of the common stock by the broker-dealers.  A selling stockholder also may
enter into option or other transactions with broker-dealers that involve the
delivery of the shares of common stock registered under this prospectus to
the broker-dealers, who then may resell or otherwise transfer these shares.
A selling stockholder also may loan or pledge the shares of common stock
registered under this prospectus to a broker-dealer and the broker-dealer may
sell the shares so loaned or upon a default may sell or otherwise transfer
the pledged shares.

     Broker, dealers, underwriters or agents participating in the
distribution of the shares of common stock registered under this prospectus
as agents may receive compensation in the form of commissions, discounts or
concessions from the selling stockholders and/or purchasers of the common
stock for whom the broker-dealers may act as agent, or to whom they may sell
as principal, or both (which compensation as to a particular broker-dealer
may be less than or in excess of customary commissions).  The selling
stockholders and any broker-dealers who act in connection with the sale of
the shares of common stock under this prospectus may be deemed to be
"underwriters" within the meaning of the Securities Act of 1933, and any
commissions they receive and proceeds of any sale of the shares of common
stock may be deemed to be underwriting discounts and commissions under the
Securities Act of 1933.  Neither we nor any of the selling stockholders can
presently estimate the amount of this compensation.  We know of no existing
arrangements between any of the selling stockholders, any other stockholder,
broker, dealer, underwriter or agent relating to the sale or distribution of
the shares of common stock registered under this prospectus.

     We will pay substantially all of the expenses relating to the registration,
offer and sale of the shares of common stock registered under this prospectus to
the public other than commissions or discounts of underwriters, broker-dealers
or agents.  We also have agreed to indemnify the selling stockholders and
specific related persons against any losses, claims, damages or liabilities
under the Securities Act of 1933 or otherwise that arise out of, or are based
upon, any untrue or alleged untrue statement of a material fact or the omission
or alleged omission instating a material fact under this registration statement
or prospectus.


                                      15
<PAGE>

     To the extent that indemnification for liabilities arising under the
Securities Act of 1933 may be permitted to our directors, officers and
controlling persons, we have been advised that, in the opinion of the SEC, this
indemnification is against public policy as expressed in the Securities Act of
1933 and is therefore, unenforceable.

                                LEGAL MATTERS

     Baker & McKenzie, San Diego, California, has passed upon the validity of
the securities offered in this prospectus.

                                  EXPERTS

     The consolidated financial statements of DAOU Systems, Inc. included in
the Company's Annual Report on Form 10-K for the year ended December 31, 1998,
have been audited by Ernst & Young LLP, independent auditors, as set forth in
their report thereon and incorporated herein by reference, which as to the
years ended December 31, 1997 and 1996 are based in part on the reports of
Deloitte & Touche LLP, independent auditors.  Such financial statements have
been incorporated herein by reference. in reliance upon such reports given on
the authority of such firm as experts in accounting and auditing.

                       WHERE YOU CAN OBTAIN MORE INFORMATION

AVAILABLE INFORMATION

     We are required to follow the reporting requirements of the Securities
Exchange Act of 1934.  To comply with these requirements, we file a number of
reports, including annual and quarterly reports, proxy statements,
information statements and other information with the SEC.  You may inspect
and copy any of this information that we have filed with the SEC at the
public reference facilities maintained by the SEC at 450 Fifth Street, N.W.,
Room 1024, Washington, D.C. 20549, and at the SEC's regional offices located
at 7 World Trade Center, Suite 1300, New York, New York 10048 and Citicorp
Center, 500 W. Madison Street, Suite 1400, Chicago, IL 60661-2511.  You may
obtain information on the operation of the public reference room by calling
the Commission at 1-800-SEC-0330.  You also may obtain copies of this
material at prescribed rates from the Public Reference Section of the SEC at
Judiciary Plaza, 450 Fifth Street, N.W., Washington, D.C. 20549.  You also
may inspect these reports, proxy statements, information statements and other
information concerning us at the offices of The Nasdaq Stock Market, Inc. at
1735 K Street, N.W., Washington, D.C.  20006.  You also may access the
materials that we file electronically with the SEC at the SEC's website
(http://www.sec.gov), which contains the reports, proxy statements,
information statements and other information that we file electronically with
the SEC.

     We have filed with the SEC a registration statement on Form S-3 under the
Securities Act of 1933, with respect to the shares covered by this prospectus.
This prospectus does not contain all of the information presented in the
registration statement, because specific parts are omitted in accordance with
the rules and regulations of the SEC.  Statements made in this prospectus as to
the contents of any contract, agreement or other document referred to are not
necessarily complete and, with respect to these contracts, agreements or other
documents filed as an exhibit to the registration statement, we refer you to
these exhibits for a more complete description of the matter involved.  Each of
these statements is deemed qualified in its entirety by this reference.


INCORPORATION OF CERTAIN INFORMATION BY REFERENCE


                                      16
<PAGE>

     We incorporate by reference in this prospectus and encourage you to read
the following documents that we have filed with the SEC to comply with the
requirements of the Securities Exchange Act of 1934:

     -    Annual Report on Form 10-K for the year ended December 31, 1998, filed
          on March 31, 1999, as amended on Form 10-K/A filed on April 30, 1999;

     -    Quarterly Reports on Form 10-Q for the quarters ended March 31, 1999,
          as filed on May 17, 1999, and June 30, 1999, as filed on August 16,
          1999;

     -    Definitive Proxy Statement on Schedule 14A filed May 20, 1999;

     -    Current Reports on Form 8-K filed January 15, 1999 and July 29, 1999;
          and

     -    The description of the common stock contained in DAOU's Registration
          Statement on Form 8-A filed on January 29, 1997, including any
          amendment filed for the purpose of updating this description.

     We also incorporate by reference as part of this prospectus and encourage
you to read all reports and other documents that we have filed (or will file)
with the SEC under the Securities Exchange Act of 1934, that are after the date
of this prospectus and before the termination of the offering of the shares
registered under this prospectus.  You should understand that, if any statement
contained in a report or document that is incorporated by reference in this
prospectus is modified or superseded, then the later filed report or document
will modify or supersede the statements contained in this prospectus.

     We will provide without charge to each person, including any beneficial
owner, to whom a copy of this prospectus is delivered, upon the written or
oral request of that person, a copy of any and all documents incorporated by
reference in this prospectus (not including, however, the exhibits to those
documents unless those exhibits are specifically incorporated by reference in
these documents).  Requests should be sent to the attention of the secretary
of our company, at DAOU Systems, Inc., 5120 Shoreham Place, San Diego,
California 92122, or you may call and ask for the secretary of our company at
(619) 452-2221.


                                      17
<PAGE>

                                      PART II

                       INFORMATION NOT REQUIRED IN PROSPECTUS

ITEM 14.  OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION.

     The estimated cumulative expenses of this registration of shares of common
stock for resale by the selling stockholders, all of which are to be paid by the
registrant in connection with the issuance and distribution of the shares being
registered, are estimated as follows:

<TABLE>
<CAPTION>
                                                                  AMOUNT
                                                              --------------
<S>                                                            <C>
Registration Fee-- Securities and Exchange Commission (1).....       $3,754
Accounting Fees and Expenses..................................        8,000
Legal Fees and Expenses.......................................       30,000
Miscellaneous.................................................        2,500
     Total                                                    --------------
                                                                    $44,254
                                                              --------------
                                                              --------------
</TABLE>

(1)  Registration fee paid upon the initial filing of this registration
     statement.

ITEM 15.  INDEMNIFICATION OF DIRECTORS AND OFFICERS.

     We hereby incorporate by reference Section 145 of the General
Corporation Law of the State of Delaware. Section 145 permits a Delaware
corporation to, under specific circumstances, indemnify any director,
officer, employee and agent of a corporation who was or is a party or is
threatened to be made a party to any threatened, pending or completed action,
suit or proceeding, whether civil, criminal, administrative or investigative,
other than an action by or in the right of the corporation. A corporation may
thus indemnify the person against expenses, attorneys' fees, judgments, fines
and amounts paid in settlement that are actually and reasonably incurred in
the suit or proceeding.

     We refer you to Article VI of our Amended and Restated Certificate of
Incorporation, and Article VII of our Bylaws, which provide for
indemnification by our company in the manner and to the full extent permitted
by Delaware law.

     We also have entered into indemnification agreements with our directors
and executive officers, in addition to the indemnification provided for in
our Bylaws.

     We currently maintain directors' and officers' liability insurance with
policy limits of $20 million.  The policy covers 100 percent of losses, after
paying the $250,000 deductible, arising from, among other things, claims of
breach of duty, neglect, error, alleged misstatement, misleading statement or
omission by the directors and officers in their capacity as such.  Payment for
loss would be made to or on our behalf where we are required or permitted to
indemnify directors or officers for covered losses required by statutory or
common law, our Amended and Restated Certificate of Incorporation or Bylaws or
by agreement.


                                      18
<PAGE>

         ITEM 16.  EXHIBITS.


  EXHIBIT        DESCRIPTION
  NUMBER

     2.1(1)  --  Agreement and Plan of Merger, dated as of January 9, 1997, by
                 and between the Registrant and DAOU Systems, Inc., a California
                 corporation.
     2.2(2)  --  Agreement and Plan of Merger, dated as of July 8, 1997, by and
                 among the Registrant, DAOU-Integrex, Inc., a Delaware
                 corporation and wholly-owned subsidiary of the Registrant,
                 Integrex Systems Corporation, a Delaware corporation, and the
                 stockholders of Integrex Systems Corporation.
   2.3+,(3)  --  Agreement and Plan of Merger, dated as of September 25, 1997,
                 by and among the Registrant, DAOU On-Line, Inc., a Delaware
                 corporation and wholly-owned subsidiary of the Registrant, On-
                 Line Networking, Inc., a New Jersey corporation, and the
                 stockholders of On-Line Networking, Inc.
   2.4+,(4)  --  Agreement and Plan of Merger, dated as of March 27, 1998, by
                 and among the Registrant, DAOU-Synexus, Inc., a Delaware
                 corporation and wholly-owned subsidiary of the Registrant,
                 Synexus Incorporated, a Pennsylvania corporation, and the
                 stockholders of Synexus Incorporated.
   2.5+,(4)  --  Agreement and Plan of Merger, dated as of March 30, 1998, by
                 and among the Registrant, DAOU-Sentient, Inc., a Delaware
                 corporation and wholly-owned subsidiary of the Registrant,
                 Sentient Systems, Inc., a Maryland corporation, and the
                 stockholders of Sentient Systems, Inc.
   2.6+,(5)  --  Agreement and Plan of Merger, dated as of June 16, 1998, by and
                 among the Registrant, DAOU-TMI, Inc., a Delaware corporation
                 and wholly-owned subsidiary of the Registrant, Technology
                 Management, Inc., an Indiana corporation, and the stockholders
                 of Technology Management, Inc.
   2.7+,(5)  --  Agreement and Plan of Merger, dated as of June 16, 1998, by and
                 among the Registrant, DAOU-TMI, Inc., a Delaware corporation
                 and wholly-owned subsidiary of the Registrant, International
                 Health Care Systems, Inc., a Florida corporation, and the
                 stockholders of International Health Care Systems, Inc.
   2.8+,(6)  --  Agreement and Plan of Merger, dated as of June 26, 1998, by and
                 among the Registrant, DAOU-RHI, Inc., a Delaware corporation
                 and wholly-owned subsidiary of the Registrant, Resources in
                 Healthcare Innovations, Inc., an Indiana corporation,
                 Healthcare Transition Resources, Inc., an Indiana corporation,
                 Ultitech Resources Group, Inc., an Indiana corporation,
                 Innovative Systems Solutions, Inc., an Indiana corporation,
                 Grand Isle Consulting, Inc., an Indiana corporation, and the
                 stockholders of Resources in Healthcare Innovations, Inc., the
                 stockholders of Healthcare Transition Resources, Inc., the
                 stockholders of Ultitech Resources Group, Inc., the
                 stockholders of Innovative Systems Solutions, Inc., and the
                 stockholders of Grand Isle Consulting, Inc.
     4.1(1)  --  Amended and Restated Certificate of Incorporation of the
                 Registrant.
     4.2(1)  --  Bylaws of the Registrant.
     4.3(1)  --  Specimen stock certificate.
     4.4(1)  --  Investors' Rights Agreement, dated October 26, 1995, between
                 the Registrant and the parties named therein.
     4.5(1)  --  Series A Preferred Stock Purchase Warrant No. 1, dated
                 October 26, 1995, between the Registrant and Needham & Company,
                 Inc.
     4.6(1)  --  Series A Preferred Stock Purchase Warrant No. 2, dated
                 October 26, 1995, between the Registrant and Needham Capital
                 S.B.I.C., L.P.
     4.7(7)  --  Certificate of Designations of the Registrant relating to the
                 Series A Convertible Preferred Stock, as filed with the
                 Secretary of State of the State of Delaware on July 23, 1999.
     4.8(7)  --  Registration Rights Agreement, dated July 26, 1999, by and
                 among the Registrant, Galen Partners III, L.P., Galen Partners
                 International III, L.P. and Galen Employee Fund III, L.P.
        5.1  --  Opinion of Baker & McKenzie as to the legality of the  common
                 stock of the Registrant.
       23.1  --  Consent of Ernst & Young LLP, independent auditors.


                                      19
<PAGE>

       23.2  --  Consent of Deloitte & Touche LLP, independent auditors.
       23.3  --  Consent of Baker & McKenzie (included in Exhibit 5.1).
       24.1  --  Power of Attorney (included on the signature page of this
                 Registration Statement).
    99.1(7)  --  Stock Purchase Agreement, dated as of July 26, 1999, by and
                 among the Registrant, Galen Partners III, L.P., Galen Partners
                 International III, L.P. and Galen Employee Fund III, L.P.
    99.2(7)  --  Voting Agreement, dated as of July 26, 1999, by and among the
                 Registrant, Daniel J. Daou, Georges J. Daou, Galen Partners
                 III, L.P., Galen Partners International III, L.P. and Galen
                 Employee Fund III, L.P.


            +    Confidential treatment has been granted with respect to certain
                 portions of this exhibit.

            (1)  Incorporated by reference to the similarly described exhibits
                 filed in connection with the registrant's Registration
                 Statement on Form SB-2, File No. 333-18155, declared effective
                 by the Commission on February 12, 1997.

            (2)  Incorporated by reference to the exhibit filed in connection
                 with the registrant's Current Report on Form 8-K filed with the
                 Commission on July 18, 1997.

            (3)  Incorporated by reference to the exhibit filed in connection
                 with the registrant's Current Report on Form 8-K filed with the
                 Commission on October 29, 1997.

            (4)  Incorporated by reference to the exhibit filed in connection
                 with the registrant's Current Report on Form 8-K filed with the
                 Commission on April 14, 1998.

            (5)  Incorporated by reference to the exhibit filed in connection
                 with the registrant's Current Report on Form 8-K filed with the
                 Commission on July 10, 1998.

            (6)  Incorporated by reference to the exhibit filed in connection
                 with the registrant's Current Report on Form 8-K filed with the
                 Commission on August 7, 1998.

            (7)  Incorporated by reference to the similarly described exhibit
                 included with the registrant's Current Report on Form 8-K filed
                 on July 29, 1999.


                                      20

<PAGE>

ITEM 17.  UNDERTAKINGS.

     (a)  The undersigned registrant hereby undertakes:

          (1)  To file, during any period in which offers or sales are being
made, a post-effective amendment to this registration statement:

               (i)   To include any prospectus required by Section 10(a)(3) of
the Securities Act;

               (ii)  To reflect in the prospectus any facts or events arising
after the effective date of the registration statement (or the most recent
post-effective amendment thereof) which, individually or in the aggregate,
represent a fundamental change in the information set forth in the
registration statement. Notwithstanding the foregoing, any increase or
decrease in volume of securities offered (if the total dollar value of
securities offered would not exceed that which was registered) and any
deviation from the low or high end of the estimated maximum offering range
may be reflected in the form of prospectus filed with the Commission pursuant
to Rule 424(b) if, in the aggregate, the changes in volume and price
represent no more than a twenty percent (20%) change in the maximum aggregate
offering price set forth in the "Calculation of Registration Fee" table in
the effective registration statement;

               (iii) To include any material information with respect to the
plan of distribution not previously disclosed in the registration statement or
any material change to such information in the registration statement;

               PROVIDED, HOWEVER, that paragraphs (a)(1)(i) and (a)(1)(ii) above
do not apply if the registration statement is on Form S-3 or Form S-8, and the
information required to be included in a post-effective amendment by those
paragraphs is contained in periodic reports filed by the registrant pursuant to
Section 13 or Section 15(d) of the Securities Exchange Act that are incorporated
by reference in the registration statement.

          (2)  That, for the purpose of determining any liability under the
Securities Act, each such post-effective amendment shall be deemed to be a new
registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

          (3)  To remove from registration by means of a post-effective
amendment any of the securities being registered which remain unsold at the
termination of the offering.

     (b)  The undersigned registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act, each filing of the
registrant's annual report pursuant to Section 13(a) or Section 15(d) of the
Exchange Act (and, where applicable, each filing of an employee benefit plan's
annual report pursuant to Section 15(d) of the Exchange Act) that is
incorporated by reference in the registration statement shall be deemed to be a
new registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona
fide offering thereof.

     (c)  Insofar as indemnification for liabilities arising under the
Securities Act may be permitted to directors, officers and controlling persons
of the registrant pursuant to the foregoing provisions, or


                                      21
<PAGE>

otherwise, the registrant has been advised that in the opinion of the
Securities and Exchange Commission such indemnification is against public
policy as expressed in the Act and is, therefore, unenforceable.  If a claim
for indemnification against such liabilities (other than the payment by the
registrant of expenses incurred or paid by a director, officer or controlling
person of the registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer or controlling person in
connection with the securities being registered, then the registrant will,
unless in the opinion of its counsel the matter has been settled by
controlling precedent, submit to a court of appropriate jurisdiction the
question whether such indemnification by it is against public policy as
expressed in the Act and will be governed by the final adjudication of such
issue.


                                      22
<PAGE>

                                     SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, the
registrant certifies that it has reasonable grounds to believe that it meets
all of the requirements for filing on Form S-3 and has duly caused this
Registration Statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in the City of San Diego, State of California, on
September 14, 1999.

                                      DAOU SYSTEMS, INC.

                                  By:  /s/ Larry D. Grandia
                                       ---------------------------------------
                                  Larry D. Grandia, Chief Executive Officer,
                                  President and Acting Chief Financial Officer

                                 POWER OF ATTORNEY

     KNOWN ALL MEN BY THESE PRESENTS, that each person whose signature
appears below on this Registration Statement hereby constitutes and appoints
Larry D. Grandia and Georges J. Daou, and each and either of them, with full
power to act without the other, his true and lawful attorney-in-fact and
agent, with full power of substitution and resubstitution, for him and in his
name, place and stead, in any and all capacities (until revoked in writing)
to sign any and all amendments (including, without limitation, post-effective
amendments and amendments thereto) to this Registration Statement, and to
file the same, with all exhibits thereto, and other documents in connection
therewith, with the Securities and Exchange Commission, granting unto said
attorneys-in-fact and agents, and each of them, full power and authority to
do and perform each and every act and thing requisite and necessary to be
done in and about the premises, as fully to all intents and purposes as he
might or could do in person, hereby ratifying and confirming all that said
attorneys-in-fact and agents or any of them, or their or his substitute or
substitutes, may lawfully do or cause to be done by virtue hereof.

     Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed below by the following persons in the
capacities and on the dates indicated.
<TABLE>
<CAPTION>
      SIGNATURE                             TITLE                                   DATE
      ---------                             -----                                   ----
<S>                           <C>                                            <C>
/s/ Larry D. Grandia          Chief Executive Officer, President and         September 14, 1999
- --------------------          Acting Chief Financial Officer (Principal
    Larry D. Grandia          Executive Officer and Acting Principal
                              Financial and Accounting Officer)


/s/ Georges J. Daou           Chairman of the Board of Directors             September 14, 1999
- --------------------
    Georges J. Daou


/s/ Richard B. Jaffe          Director                                       September 14, 1999
- --------------------
    Richard B. Jaffe


/s/ David W. Jahns            Director                                       September 14, 1999
- --------------------
    David W. Jahns
</TABLE>

                                      23
<PAGE>
<TABLE>
<CAPTION>
      SIGNATURE                             TITLE                                   DATE
      ---------                             -----                                   ----
<S>                              <C>                                         <C>
/s/ John H. Moragne              Director                                    September 14, 1999
- ------------------------------
    John H. Moragne


/s/ Kevin M. Fickenscher, M.D.   Director                                    September 14, 1999
- ------------------------------
    Kevin M. Fickenscher, M.D.
</TABLE>

                                      24
<PAGE>

                                 INDEX TO EXHIBITS


  EXHIBIT        DESCRIPTION
  NUMBER

    2.1(1)   --  Agreement and Plan of Merger, dated as of January 9, 1997, by
                 and between the Registrant and DAOU Systems, Inc., a
                 California corporation.
    2.2(2)   --  Agreement and Plan of Merger, dated as of July 8, 1997, by and
                 among the Registrant, DAOU-Integrex, Inc., a Delaware
                 corporation and wholly-owned subsidiary of the Registrant,
                 Integrex Systems Corporation, a Delaware corporation, and the
                 stockholders of Integrex Systems Corporation.
  2.3+,(3)   --  Agreement and Plan of Merger, dated as of September 25, 1997,
                 by and among the Registrant, DAOU On-Line, Inc., a Delaware
                 corporation and wholly-owned subsidiary of the Registrant, On-
                 Line Networking, Inc., a New Jersey corporation, and the
                 stockholders of On-Line Networking, Inc.
  2.4+,(4)   --  Agreement and Plan of Merger, dated as of March 27, 1998, by
                 and among the Registrant, DAOU-Synexus, Inc., a Delaware
                 corporation and wholly-owned subsidiary of the Registrant,
                 Synexus Incorporated, a Pennsylvania corporation, and the
                 stockholders of Synexus Incorporated.
  2.5+,(4)   --  Agreement and Plan of Merger, dated as of March 30, 1998, by
                 and among the Registrant, DAOU-Sentient, Inc., a Delaware
                 corporation and wholly-owned subsidiary of the Registrant,
                 Sentient Systems, Inc., a Maryland corporation, and the
                 stockholders of Sentient Systems, Inc.
  2.6+,(5)   --  Agreement and Plan of Merger, dated as of June 16, 1998, by
                 and among the Registrant, DAOU-TMI, Inc., a Delaware
                 corporation and wholly-owned subsidiary of the Registrant,
                 Technology Management, Inc., an Indiana corporation, and the
                 stockholders of Technology Management, Inc.
  2.7+,(5)   --  Agreement and Plan of Merger, dated as of June 16, 1998, by
                 and among the Registrant, DAOU-TMI, Inc., a Delaware
                 corporation and wholly-owned subsidiary of the Registrant,
                 International Health Care Systems, Inc., a Florida
                 corporation, and the stockholders of International Health Care
                 Systems, Inc.
  2.8+,(6)   --  Agreement and Plan of Merger, dated as of June 26, 1998, by
                 and among the Registrant, DAOU-RHI, Inc., a Delaware
                 corporation and wholly-owned subsidiary of the Registrant,
                 Resources in Healthcare Innovations, Inc., an Indiana
                 corporation, Healthcare Transition Resources, Inc., an Indiana
                 corporation, Ultitech Resources Group, Inc., an Indiana
                 corporation, Innovative Systems Solutions, Inc., an Indiana
                 corporation, Grand Isle Consulting, Inc., an Indiana
                 corporation, and the stockholders of Resources in Healthcare
                 Innovations, Inc., the stockholders of Healthcare Transition
                 Resources, Inc., the stockholders of Ultitech Resources Group,
                 Inc., the stockholders of Innovative Systems Solutions, Inc.,
                 and the stockholders of Grand Isle Consulting, Inc.
    4.1(1)   --  Amended and Restated Certificate of Incorporation of the
                 Registrant.
    4.2(1)   --  Bylaws of the Registrant.
    4.3(1)   --  Specimen stock certificate.
    4.4(1)   --  Investors' Rights Agreement, dated October 26, 1995, between
                 the Registrant and the parties named therein.
    4.5(1)   --  Series A Preferred Stock Purchase Warrant No. 1, dated
                 October 26, 1995, between the Registrant and Needham &
                 Company, Inc.
    4.6(1)   --  Series A Preferred Stock Purchase Warrant No. 2, dated
                 October 26, 1995, between the Registrant and Needham Capital
                 S.B.I.C., L.P.
    4.7(7)   --  Certificate of Designations of the Registrant relating to the
                 Series A Convertible Preferred Stock, as filed with the
                 Secretary of State of the State of Delaware on July 23, 1999.
    4.8(7)   --  Registration Rights Agreement, dated July 26, 1999, by and
                 among the Registrant, Galen Partners III, L.P., Galen Partners
                 International III, L.P. and Galen Employee Fund III, L.P.
                                      25
<PAGE>

       5.1   --  Opinion of Baker & McKenzie as to the legality of the  common
                 stock of the Registrant.
      23.1   --  Consent of Ernst & Young LLP, independent auditors.
      23.2   --  Consent of Deloitte & Touche LLP, independent auditors.
      23.3   --  Consent of Baker & McKenzie (included in Exhibit 5.1).
      24.1   --  Power of Attorney (included on the signature page of this
                 Registration Statement).
   99.1(7)   --  Stock Purchase Agreement, dated as of July 26, 1999, by and
                 among the Registrant, Galen Partners III, L.P., Galen Partners
                 International III, L.P. and Galen Employee Fund III, L.P.
   99.2(7)   --  Voting Agreement, dated as of July 26, 1999, by and among the
                 Registrant, Daniel J. Daou, Georges J. Daou, Galen Partners
                 III, L.P., Galen Partners International III, L.P. and Galen
                 Employee Fund III, L.P.

+    Confidential treatment has been granted with respect to certain portions of
     this exhibit.

(1)  Incorporated by reference to the similarly described exhibits filed in
     connection with the registrant's Registration Statement on Form SB-2, File
     No. 333-18155, declared effective by the Commission on February 12, 1997.

(2)  Incorporated by reference to the exhibit filed in connection with the
     registrant's Current Report on Form 8-K filed with the Commission on July
     18, 1997.

(3)  Incorporated by reference to the exhibit filed in connection with the
     registrant's Current Report on Form 8-K filed with the Commission on
     October 29, 1997.

(4)  Incorporated by reference to the exhibit filed in connection with the
     registrant's Current Report on Form 8-K filed with the Commission on April
     14, 1998.

(5)  Incorporated by reference to the exhibit filed in connection with the
     registrant's Current Report on Form 8-K filed with the Commission on July
     10, 1998.

(6)  Incorporated by reference to the exhibit filed in connection with the
     registrant's Current Report on Form 8-K filed with the Commission on August
     7, 1998.

(7)  Incorporated by reference to the similarly described exhibit included with
     the registrant's Current Report on Form 8-K filed on July 29, 1999.


                                      26


<PAGE>

                               EXHIBIT 5.1

                       Opinion of Baker & McKenzie



September 14, 1999

DAOU Systems, Inc.
5120 Shoreham Place
San Diego, CA  92122

Ladies and Gentlemen:

We have acted as counsel to DAOU Systems, Inc., a Delaware corporation (the
"Company"), in connection with its filing with the Securities and Exchange
Commission under the Securities Act of 1933, as amended (the "Securities
Act"), of a Registration Statement on Form S-3, including exhibits thereto
(the "Registration Statement"), covering up to 2,750,000 shares of the
Company's common stock, par value $0.001 per share (the "Shares").

We have examined the originals, or photostatic or certified copies, of such
records of the Company, certificates of officers of the Company and of public
officials, and such other documents as we have deemed relevant and necessary
as the basis of the opinion set forth below. In such examination, we have
assumed the genuineness of all signatures, the authenticity of all documents
submitted to us as photostatic or certified copies and the authenticity of
the originals of such copies.

Based upon our examination, we are of the opinion that the Shares have been
validly authorized and are legally issued, fully paid and non-assessable.

We express no opinion as to the applicability of, compliance with, or effect
of federal law or the law of any jurisdiction other than the General
Corporation Law of the State of Delaware.

We hereby consent to the use of our opinion as herein set forth as an exhibit
to the Registration Statement and to the use of our name under the caption
"Legal Matters" in the prospectus forming a part of the Registration
Statement. This consent is not to be construed as an admission that we are a
person whose consent is required to be filed with the Registration Statement
under the provisions of the Securities Act.


Very truly yours,


BAKER & MCKENZIE


/s/ Baker & McKenzie



<PAGE>

                              EXHIBIT 23.1

                     Consent of Ernst & Young LLP


DAOU Systems, Inc.:

We consent to the reference to our firm under the caption "Experts" in the
Registration Statement on Form S-3 and related Prospectus of DAOU Systems, Inc.
for the registration of 2,750,000 shares of its common stock and to the
incorporation by reference therein of our report dated February 12, 1999,
with respect to the consolidated financial statements of DAOU Systems, Inc.
included in its Annual Report on Form 10-K for the year ended December 31,
1998, filed with the Securities and Exchange Commission.

   /s/ ERNST & YOUNG LLP
- -----------------------------


San Diego, California
September 10, 1999




<PAGE>



INDEPENDENT AUDITORS' CONSENT


     We consent to the incorporation by reference in the registration
statement on Form S-3 of DAOU Systems, Inc. of our report dated February 13,
1998 on the financial statements of Sentient Systems, Inc., appearing in the
Annual Report on Form 10-K of DAOU Systems, Inc. for the year ended
December 31, 1998.







/s/ Deloitte & Touche LLP

McLean, Virginia
September 10, 1999


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