<PAGE>
----------------------------------
OMB APPROVAL
----------------------------------
OMB Number: 3235-0287
Expires: September 30, 1998
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hours per response....0.5
----------------------------------
U.S. SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 4
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934,
Section 17(a) of the Public Utility Holding Company Act of 1935 or
Section 30(f) of the Investment Company Act of 1940
[ ] Check this box if no longer subject of Section 16. Form 4 or Form 5
obligations may continue. See Instruction 1(b).
================================================================================
1. Name and Address of Reporting Person*
SEE JACKIE R.
- --------------------------------------------------------------------------------
(Last) (First) (Middle)
100 NORTH ARLINGTON AVENUE, SUITE 23P
- --------------------------------------------------------------------------------
(Street)
RENO NEVADA 89501
- --------------------------------------------------------------------------------
(City) (State) (Zip)
================================================================================
2. Issuer Name and Ticker or Trading Symbol
HARVARD SCIENTIFIC CORP. HVSF
================================================================================
3. IRS or Social Security Number of Reporting Person (Voluntary)
================================================================================
4. Statement for Month/Year
All Mo.'s' beg. 12/96 to 2/98 including unreported shares excluded from
previously filed Form 4 reports.
================================================================================
5. If Amendment, Date of Original (Month/Year)
================================================================================
6. Relationship of Reporting Person to Issuer
(Check all applicable)
[ X ] Director [ X ] 10% Owner
[ ] Officer (give title below) [ ] Other (specify below)
================================================================================
7. Individual or Joint/Group Filing (Check applicable line)
[ X ] Form filed by one Reporting Person [ ] Form filed by more than one
Reporting Person
================================================================================
Table I -- Non-Derivative Securities Acquired, Disposed of,
or Beneficially Owned
================================================================================
<TABLE>
<CAPTION>
6.
4. 5. Owner-
Securities Acquired (A) or Amount of ship
3. Disposed of (D) Securities Form: 7.
Transaction (Instr. 3, 4 and 5) Beneficially Direct Nature of
2. Code ----------------------------- Owned at End (D) or Indirect
1. Transaction (Instr. 8) (A) of Month Indirect Beneficial
Title of Security Date ------------ Amount or Price (Instr. 3 (I) Ownership
(Instr. 3) (mm/dd/yy) Code V (D) and 4) (Instr.4) (Instr. 4)
- ------------------------------------------------------------------------------------------------------------------------------------
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C>
COMMON STOCK 7/02/96 S 400 D $ 34.40 665,021 I BIOSPHERE*V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 8/21/96 S 250 D $ 16.10 I BIOSPHERE*V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 8/22/96 S 350 D $ 27.90 I BIOSPHERE*V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 8/29/96 S 500 D $ 20.60 I BIOSPHERE*V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 8/30/96 S 500 D $ 26.60 663,421 I BIOSPHERE*V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/4/96 S 500 D $ 27.80 I BIOSPHERE*V
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
====================================================================================================================================
</TABLE>
CONTINUED ON ATTACHMENT (add'l 10 pages)
* If the Form is filed by more than one Reporting Person, see Instruction
4(b)(v).
Reminder: Report on a separate line for each class of securities beneficially
owned directly or indirectly.
Page 1 of 12
<PAGE>
FORM 4 CONTINUED...
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 10549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
- --------------------------------------------------------------------------------
1 Name and Address |2 Issuer Name and Ticker or Trading Symbol
Reporting Person |
SEE JACKIE R. | HARVARD SCIENTIFIC CORP. HVSF
-----------------------------------|------------------------------------------
(Last) (First) (Middle) |4 Statement for
| Month/Year
100 N. Arlington Avenue, Suite 23P|
-----------------------------------| All months beginning 12/96 to 2/98
(Street) | which include all unreported shares
| exluded1from previously filed Form 4's
Reno Nevada (89501)|
-----------------------------------|
(City) (State) (Zip) |
|
- -------------------------------------------------------------------------------
<TABLE>
<CAPTION>
6.
4. 5. Owner-
Securities Acquired (A) or Amount of ship
3. Disposed of (D) Securities Form: 7.
Transaction (Instr. 3, 4 and 5) Beneficially Direct Nature of
2. Code ------------------------------- Owned at End (D) or Indirect
1. Transaction (Instr. 8) (A) of Month Indirect Beneficial
Title of Security Date ------------ Amount or Price (Instr. 3 (I) Ownership
(Instr. 3) (mm/dd/yy) Code V (D) and 4) (Instr.4) (Instr. 4)
====================================================================================================================================
Reference Legend:
*** All transactions have been restated to reflect the 1 for 10 reverse stock
split effective February 2, 1998.
*V Biosphere Technology Inc. ("BTI") is a shareholder of the issuer. The person
reporting may be deemed to beneficially own the shares of the issuer's
common stock, held by BTI.
*X Outstanding balances incorporates transactions reported on previous Form
4's.
*W The Anita Wassgren See Trust is a shareholder of the issuer. The reporting
person's spouse is the settler and trustee of the Trust and, accordingly,
the reporting person may be deemed to beneficially own the issuer's shares
held by the Trust.
J-1 Shares loaned, and it is expected they will be returned at a later date.
J-2 Shares issued in lieu of a legal settlement.
J-3 Shares issued in exchange for intellectual rights.
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C>
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/18/96 S 20,000 D $ 10.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/18/96 S 300 D $ 23.30 642,621 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/20/96 S 220 D $ 23.20 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/23/96 S 800 D $ 21.40 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/24/96 S 500 D $ 23.20 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/27/96 S 500 D $ 24.90 631,851 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/8/97 S 1,000 D $ 29.40 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/20/97 S 150 D $ 32.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/21/97 S 150 D $ 35.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/22/97 S 150 D $ 40.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/23/97 S 150 D $ 41.56 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/24/97 S 150 D $ 39.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/27/97 S 150 D $ 40.31 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/28/97 S 150 D $ 45.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/29/97 S 150 D $ 45.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/31/97 S 150 D $ 45.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/31/97 S 150 D $ 46.88 629,351 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/3/97 S 150 D $ 63.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/4/97 S 150 D $ 83.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/4/97 S 150 D $ 83.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/5/97 S 150 D $ 72.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/5/97 S 300 D $ 81.90 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/6/97 S 150 D $ 58.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/7/97 S 150 D $ 73.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/10/97 S 150 D $ 75.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/11/97 S 150 D $ 73.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>
Page 2 of 12
<PAGE>
FORM 4 CONTINUED...
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 10549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
- --------------------------------------------------------------------------------
1 Name and Address |2 Issuer Name and Ticker or Trading Symbol
Reporting Person |
SEE JACKIE R. | HARVARD SCIENTIFIC CORP. HVSF
-----------------------------------|------------------------------------------
(Last) (First) (Middle) |4 Statement for
| Month/Year
100 N. Arlington Avenue, Suite 23P|
-----------------------------------| All months beginning 12/96 to 2/98
(Street) | which include all unreported shares
| exluded1from previously filed Form 4's
Reno Nevada (89501)|
-----------------------------------|
(City) (State) (Zip) |
|
- -------------------------------------------------------------------------------
<TABLE>
<CAPTION>
6.
4. 5. Owner-
Securities Acquired (A) or Amount of ship
3. Disposed of (D) Securities Form: 7.
Transaction (Instr. 3, 4 and 5) Beneficially Direct Nature of
2. Code ------------------------------- Owned at End (D) or Indirect
1. Transaction (Instr. 8) (A) of Month Indirect Beneficial
Title of Security Date ------------ Amount or Price (Instr. 3 (I) Ownership
(Instr. 3) (mm/dd/yy) Code V (D) and 4) (Instr.4) (Instr. 4)
====================================================================================================================================
Reference Legend:
*** All transactions have been restated to reflect the 1 for 10 reverse stock
split effective February 2, 1998.
*V Biosphere Technology Inc. ("BTI") is a shareholder of the issuer. The person
reporting may be deemed to beneficially own the shares of the issuer's
common stock, held by BTI.
*X Outstanding balances incorporates transactions reported on previous Form
4's.
*W The Anita Wassgren See Trust is a shareholder of the issuer. The reporting
person's spouse is the settler and trustee of the Trust and, accordingly,
the reporting person may be deemed to beneficially own the issuer's shares
held by the Trust.
J-1 Shares loaned, and it is expected they will be returned at a later date.
J-2 Shares issued in lieu of a legal settlement.
J-3 Shares issued in exchange for intellectual rights.
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C>
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/11/97 S 150 D $ 71.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/12/97 S 150 D $ 71.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/13/97 S 150 D $ 73.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/14/97 S 150 D $ 73.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/18/97 S 150 D $ 72.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/18/97 S 400 D $ 70.10 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/19/97 S 150 D $ 73.13 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/20/97 S 150 D $ 75.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/20/97 S 200 D $ 71.20 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/21/97 S 150 D $ 87.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/21/97 S 150 D $ 87.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/24/97 S 150 D $ 80.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/24/97 S 150 D $ 76.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/25/97 S 150 D $ 72.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/26/97 S 150 D $ 71.88 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/27/97 S 150 D $ 70.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/28/97 S 150 D $ 65.00 625,001 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/3/97 S 150 D $ 84.40 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/3/97 S 200 D $ 62.90 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/4/97 S 200 D $ 71.20 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/4/97 S 200 D $ 78.85 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/5/97 S 150 D $ 95.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/5/97 S 200 D $ 76.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/6/97 S 150 D $ 70.10 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/6/97 S 200 D $ 73.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/7/97 S 150 D $ 67.70 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>
Page 3 of 12
<PAGE>
FORM 4 CONTINUED...
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 10549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
- --------------------------------------------------------------------------------
1 Name and Address |2 Issuer Name and Ticker or Trading Symbol
Reporting Person |
SEE JACKIE R. | HARVARD SCIENTIFIC CORP. HVSF
-----------------------------------|------------------------------------------
(Last) (First) (Middle) |4 Statement for
| Month/Year
100 N. Arlington Avenue, Suite 23P|
-----------------------------------| All months beginning 12/96 to 2/98
(Street) | which include all unreported shares
| exluded1from previously filed Form 4's
Reno Nevada (89501)|
-----------------------------------|
(City) (State) (Zip) |
|
- -------------------------------------------------------------------------------
<TABLE>
<CAPTION>
6.
4. 5. Owner-
Securities Acquired (A) or Amount of ship
3. Disposed of (D) Securities Form: 7.
Transaction (Instr. 3, 4 and 5) Beneficially Direct Nature of
2. Code ------------------------------- Owned at End (D) or Indirect
1. Transaction (Instr. 8) (A) of Month Indirect Beneficial
Title of Security Date ------------ Amount or Price (Instr. 3 (I) Ownership
(Instr. 3) (mm/dd/yy) Code V (D) and 4) (Instr.4) (Instr. 4)
====================================================================================================================================
Reference Legend:
*** All transactions have been restated to reflect the 1 for 10 reverse stock
split effective February 2, 1998.
*V Biosphere Technology Inc. ("BTI") is a shareholder of the issuer. The person
reporting may be deemed to beneficially own the shares of the issuer's
common stock, held by BTI.
*X Outstanding balances incorporates transactions reported on previous Form
4's.
*W The Anita Wassgren See Trust is a shareholder of the issuer. The reporting
person's spouse is the settler and trustee of the Trust and, accordingly,
the reporting person may be deemed to beneficially own the issuer's shares
held by the Trust.
J-1 Shares loaned, and it is expected they will be returned at a later date.
J-2 Shares issued in lieu of a legal settlement.
J-3 Shares issued in exchange for intellectual rights.
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C>
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/7/97 S 200 D $ 72.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/10/97 S 150 D $ 65.30 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/10/97 S 200 D $ 68.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/11/97 S 200 D $ 69.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/12/97 S 150 D $ 64.10 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/12/97 S 200 D $ 67.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/13/97 S 200 D $ 65.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/14/97 S 200 D $ 61.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/17/97 S 200 D $ 63.13 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/18/97 S 200 D $ 66.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/19/97 S 200 D $ 66.88 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/20/97 S 200 D $ 66.88 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/24/97 S 200 D $ 63.13 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/24/97 S 200 D $ 64.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/25/97 S 200 D $ 66.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/26/97 S 200 D $ 68.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/26/97 S 200 D $ 68.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/27/97 S 200 D $ 66.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 3/31/97 S 200 D $ 64.38 654,701 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 4/1/97 S 200 D $ 58.13 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 4/2/97 S 200 D $ 47.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 4/3/97 S 200 D $ 47.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 4/4/97 S 200 D $ 45.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 4/7/97 S 200 D $ 47.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 4/8/97 S 200 D $ 45.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 4/9/97 S 200 D $ 43.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>
4 of 12
<PAGE>
FORM 4 CONTINUED...
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 10549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
- --------------------------------------------------------------------------------
1 Name and Address |2 Issuer Name and Ticker or Trading Symbol
Reporting Person |
SEE JACKIE R. | HARVARD SCIENTIFIC CORP. HVSF
-----------------------------------|------------------------------------------
(Last) (First) (Middle) |4 Statement for
| Month/Year
100 N. Arlington Avenue, Suite 23P|
-----------------------------------| All months beginning 12/96 to 2/98
(Street) | which include all unreported shares
| exluded1from previously filed Form 4's
Reno Nevada (89501)|
-----------------------------------|
(City) (State) (Zip) |
|
- -------------------------------------------------------------------------------
<TABLE>
<CAPTION>
6.
4. 5. Owner-
Securities Acquired (A) or Amount of ship
3. Disposed of (D) Securities Form: 7.
Transaction (Instr. 3, 4 and 5) Beneficially Direct Nature of
2. Code ------------------------------- Owned at End (D) or Indirect
1. Transaction (Instr. 8) (A) of Month Indirect Beneficial
Title of Security Date ------------ Amount or Price (Instr. 3 (I) Ownership
(Instr. 3) (mm/dd/yy) Code V (D) and 4) (Instr.4) (Instr. 4)
====================================================================================================================================
Reference Legend:
*** All transactions have been restated to reflect the 1 for 10 reverse stock
split effective February 2, 1998.
*V Biosphere Technology Inc. ("BTI") is a shareholder of the issuer. The person
reporting may be deemed to beneficially own the shares of the issuer's
common stock, held by BTI.
*X Outstanding balances incorporates transactions reported on previous Form
4's.
*W The Anita Wassgren See Trust is a shareholder of the issuer. The reporting
person's spouse is the settler and trustee of the Trust and, accordingly,
the reporting person may be deemed to beneficially own the issuer's shares
held by the Trust.
J-1 Shares loaned, and it is expected they will be returned at a later date.
J-2 Shares issued in lieu of a legal settlement.
J-3 Shares issued in exchange for intellectual rights.
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C>
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 4/11/97 S 200 D $ 45.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 4/14/97 S 200 D $ 49.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 4/15/97 S 200 D $ 51.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 4/16/97 S 200 D $ 50.31 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 4/18/97 S 251 D $ 42.50 652,250 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 5/23/97 S 150 D $ 22.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 5/27/97 S 150 D $ 20.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 5/27/97 S 300 D $ 27.50 D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 5/27/97 S 250 D $ 27.50 D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 5/28/97 S 750 D $ 26.30 D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 5/28/97 S 250 D $ 26.90 D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 5/28/97 S 150 D $ 20.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 5/29/97 S 150 D $ 19.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 5/30/97 S 150 D $ 18.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 5/30/97 S 100 D $ 19.10 D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 5/30/97 S 100 D $ 19.40 649,750 D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/2/97 S 150 D $ 18.13 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/3/97 S 150 D $ 18.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/3/97 S 150 D $ 19.40 D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/3/97 S 100 D $ 10.40 D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/4/97 S 150 D $ 20.31 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/5/97 S 150 D $ 20.31 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/6/97 S 150 D $ 21.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/9/97 S 150 D $ 20.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/10/97 S 150 D $ 20.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/10/97 J 100,000 A I Anita Wassgren
See Trust *W
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>
5 of 12
<PAGE>
FORM 4 CONTINUED...
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 10549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
- --------------------------------------------------------------------------------
1 Name and Address |2 Issuer Name and Ticker or Trading Symbol
Reporting Person |
SEE JACKIE R. | HARVARD SCIENTIFIC CORP. HVSF
-----------------------------------|------------------------------------------
(Last) (First) (Middle) |4 Statement for
| Month/Year
100 N. Arlington Avenue, Suite 23P|
-----------------------------------| All months beginning 12/96 to 2/98
(Street) | which include all unreported shares
| exluded1from previously filed Form 4's
Reno Nevada (89501)|
-----------------------------------|
(City) (State) (Zip) |
|
- -------------------------------------------------------------------------------
<TABLE>
<CAPTION>
6.
4. 5. Owner-
Securities Acquired (A) or Amount of ship
3. Disposed of (D) Securities Form: 7.
Transaction (Instr. 3, 4 and 5) Beneficially Direct Nature of
2. Code ------------------------------- Owned at End (D) or Indirect
1. Transaction (Instr. 8) (A) of Month Indirect Beneficial
Title of Security Date ------------ Amount or Price (Instr. 3 (I) Ownership
(Instr. 3) (mm/dd/yy) Code V (D) and 4) (Instr.4) (Instr. 4)
====================================================================================================================================
Reference Legend:
*** All transactions have been restated to reflect the 1 for 10 reverse stock
split effective February 2, 1998.
*V Biosphere Technology Inc. ("BTI") is a shareholder of the issuer. The person
reporting may be deemed to beneficially own the shares of the issuer's
common stock, held by BTI.
*X Outstanding balances incorporates transactions reported on previous Form
4's.
*W The Anita Wassgren See Trust is a shareholder of the issuer. The reporting
person's spouse is the settler and trustee of the Trust and, accordingly,
the reporting person may be deemed to beneficially own the issuer's shares
held by the Trust.
J-1 Shares loaned, and it is expected they will be returned at a later date.
J-2 Shares issued in lieu of a legal settlement.
J-3 Shares issued in exchange for intellectual rights.
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C>
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/10/97 A 300,000 A D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/11/97 J 10,000 A I Anita Wassgren
See Trust *W
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/11/97 G 1,000 D $ - D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/11/97 G 1,000 D $ - D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/11/97 G 1,000 D $ - D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/11/97 G 1,000 D $ - D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/11/97 G 5,000 D $ - D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/11/97 G 1,000 D $ - D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/11/97 G 10,000 D $ - D
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/12/97 S 150 D $ 20.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/13/97 S 150 D $ 19.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/13/97 S 150 D $ 19.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/16/97 S 150 D $ 12.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/17/97 S 150 D $ 14.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/18/97 S 150 D $ 14.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/19/97 S 150 D $ 15.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/20/97 S 150 D $ 15.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/23/97 S 150 D $ 14.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/24/97 S 250 D $ 13.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/26/97 S 250 D $ 13.44 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/26/97 S 250 D $ 13.44 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/27/97 S 250 D $ 10.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 6/30/97 S 250 D $ 10.63 1,035,850 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/1/97 S 250 D $ 10.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/2/97 S 250 D $ 10.31 I Biosphere *V
- -----------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/3/97 S 250 D $ 10.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>
6 of 12
<PAGE>
FORM 4 CONTINUED...
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 10549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
- --------------------------------------------------------------------------------
1 Name and Address |2 Issuer Name and Ticker or Trading Symbol
Reporting Person |
SEE JACKIE R. | HARVARD SCIENTIFIC CORP. HVSF
-----------------------------------|------------------------------------------
(Last) (First) (Middle) |4 Statement for
| Month/Year
100 N. Arlington Avenue, Suite 23P|
-----------------------------------| All months beginning 12/96 to 2/98
(Street) | which include all unreported shares
| exluded1from previously filed Form 4's
Reno Nevada (89501)|
-----------------------------------|
(City) (State) (Zip) |
|
- -------------------------------------------------------------------------------
<TABLE>
<CAPTION>
6.
4. 5. Owner-
Securities Acquired (A) or Amount of ship
3. Disposed of (D) Securities Form: 7.
Transaction (Instr. 3, 4 and 5) Beneficially Direct Nature of
2. Code ------------------------------- Owned at End (D) or Indirect
1. Transaction (Instr. 8) (A) of Month Indirect Beneficial
Title of Security Date ------------ Amount or Price (Instr. 3 (I) Ownership
(Instr. 3) (mm/dd/yy) Code V (D) and 4) (Instr.4) (Instr. 4)
====================================================================================================================================
Reference Legend:
*** All transactions have been restated to reflect the 1 for 10 reverse stock
split effective February 2, 1998.
*V Biosphere Technology Inc. ("BTI") is a shareholder of the issuer. The person
reporting may be deemed to beneficially own the shares of the issuer's
common stock, held by BTI.
*X Outstanding balances incorporates transactions reported on previous Form
4's.
*W The Anita Wassgren See Trust is a shareholder of the issuer. The reporting
person's spouse is the settler and trustee of the Trust and, accordingly,
the reporting person may be deemed to beneficially own the issuer's shares
held by the Trust.
J-1 Shares loaned, and it is expected they will be returned at a later date.
J-2 Shares issued in lieu of a legal settlement.
J-3 Shares issued in exchange for intellectual rights.
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C>
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/7/97 S 250 D $ 10.31 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/8/97 S 250 D $ 10.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/9/97 S 250 D $ 9.69 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/10/97 S 250 D $ 9.69 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/11/97 S 250 D $ 9.69 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/14/97 S 250 D $ 13.13 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/16/97 S 250 D $ 20.94 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/16/97 S 250 D $ 20.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK-LOANED 7/16/97 J-1 3,500 D $ - I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/17/97 S 250 D $ 15.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/21/97 S 250 D $ 14.69 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/22/97 S 250 D $ 11.88 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/24/97 S 250 D $ 10.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/24/97 S 250 D $ 11.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/24/97 J-2 25,000 D $ - I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/25/97 S 250 D $ 10.94 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/28/97 S 250 D $ 10.31 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/29/97 S 250 D $ 10.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/30/97 S 250 D $ 10.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 7/31/97 S 250 D $ 10.00 1,002,100 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/9/97 S 350 D $ 16.88 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/9/97 S 250 D $ 16.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/11/97 S 250 D $ 17.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/11/97 S 250 D $ 16.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/12/97 S 250 D $ 15.88 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/15/97 S 250 D $ 17.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>
7 of 12
<PAGE>
FORM 4 CONTINUED ...
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 10549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
- --------------------------------------------------------------------------------
1 Name and Address |2 Issuer Name and Ticker or Trading Symbol
Reporting Person |
SEE JACKIE R. | HARVARD SCIENTIFIC CORP. HVSF
-----------------------------------|------------------------------------------
(Last) (First) (Middle) |4 Statement for
| Month/Year
100 N. Arlington Avenue, Suite 23P|
-----------------------------------| All months beginning 12/96 to 2/98
(Street) | which include all unreported shares
| exluded1from previously filed Form 4's
Reno Nevada (89501)|
-----------------------------------|
(City) (State) (Zip) |
|
- -------------------------------------------------------------------------------
<TABLE>
<CAPTION>
6.
4. 5. Owner-
Securities Acquired (A) or Amount of ship
3. Disposed of (D) Securities Form: 7.
Transaction (Instr. 3, 4 and 5) Beneficially Direct Nature of
2. Code ------------------------------- Owned at End (D) or Indirect
1. Transaction (Instr. 8) (A) of Month Indirect Beneficial
Title of Security Date ------------ Amount or Price (Instr. 3 (I) Ownership
(Instr. 3) (mm/dd/yy) Code V (D) and 4) (Instr.4) (Instr. 4)
====================================================================================================================================
Reference Legend:
*** All transactions have been restated to reflect the 1 for 10 reverse stock
split effective February 2, 1998.
*V Biosphere Technology Inc. ("BTI") is a shareholder of the issuer. The person
reporting may be deemed to beneficially own the shares of the issuer's
common stock, held by BTI.
*X Outstanding balances incorporates transactions reported on previous Form
4's.
*W The Anita Wassgren See Trust is a shareholder of the issuer. The reporting
person's spouse is the settler and trustee of the Trust and, accordingly,
the reporting person may be deemed to beneficially own the issuer's shares
held by the Trust.
J-1 Shares loaned, and it is expected they will be returned at a later date.
J-2 Shares issued in lieu of a legal settlement.
J-3 Shares issued in exchange for intellectual rights.
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C>
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/16/97 S 250 D $ 17.19 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/17/97 S 250 D $ 16.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/18/97 S 250 D $ 16.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/19/97 S 250 D $ 16.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/22/97 S 250 D $ 16.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/23/97 S 250 D $ 16.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/24/97 S 150 D $ 15.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/24/97 S 100 D $ 15.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/25/97 S 250 D $ 15.94 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/26/97 S 250 D $ 15.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/29/97 S 250 D $ 14.69 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 9/30/97 S 250 D $ 14.80 997,750 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/1/97 S 250 D $ 15.31 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/2/97 S 250 D $ 15.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/2/97 S 150 D $ 15.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/2/97 S 100 D $ 15.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/3/97 S 250 D $ 16.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/6/97 S 250 D $ 15.88 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/7/97 S 250 D $ 14.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/8/97 S 250 D $ 15.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/9/97 S 250 D $ 14.69 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/10/97 S 250 D $ 14.69 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/13/97 S 250 D $ 15.94 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/15/97 S 250 D $ 15.94 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/15/97 S 250 D $ 15.94 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/16/97 S 250 D $ 16.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>
8 of 12
<PAGE>
FORM 4 CONTINUED...
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 10549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
- --------------------------------------------------------------------------------
1 Name and Address |2 Issuer Name and Ticker or Trading Symbol
Reporting Person |
SEE JACKIE R. | HARVARD SCIENTIFIC CORP. HVSF
-----------------------------------|------------------------------------------
(Last) (First) (Middle) |4 Statement for
| Month/Year
100 N. Arlington Avenue, Suite 23P|
-----------------------------------| All months beginning 12/96 to 2/98
(Street) | which include all unreported shares
| exluded1from previously filed Form 4's
Reno Nevada (89501)|
-----------------------------------|
(City) (State) (Zip) |
|
- -------------------------------------------------------------------------------
<TABLE>
<CAPTION>
6.
4. 5. Owner-
Securities Acquired (A) or Amount of ship
3. Disposed of (D) Securities Form: 7.
Transaction (Instr. 3, 4 and 5) Beneficially Direct Nature of
2. Code ------------------------------- Owned at End (D) or Indirect
1. Transaction (Instr. 8) (A) of Month Indirect Beneficial
Title of Security Date ------------ Amount or Price (Instr. 3 (I) Ownership
(Instr. 3) (mm/dd/yy) Code V (D) and 4) (Instr.4) (Instr. 4)
====================================================================================================================================
Reference Legend:
*** All transactions have been restated to reflect the 1 for 10 reverse stock
split effective February 2, 1998.
*V Biosphere Technology Inc. ("BTI") is a shareholder of the issuer. The person
reporting may be deemed to beneficially own the shares of the issuer's
common stock, held by BTI.
*X Outstanding balances incorporates transactions reported on previous Form
4's.
*W The Anita Wassgren See Trust is a shareholder of the issuer. The reporting
person's spouse is the settler and trustee of the Trust and, accordingly,
the reporting person may be deemed to beneficially own the issuer's shares
held by the Trust.
J-1 Shares loaned, and it is expected they will be returned at a later date.
J-2 Shares issued in lieu of a legal settlement.
J-3 Shares issued in exchange for intellectual rights.
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C>
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/17/97 S 250 D $ 15.76 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/20/97 S 250 D $ 16.56 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/21/97 S 250 D $ 17.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/22/97 S 250 D $ 16.88 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/23/97 S 250 D $ 15.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/24/97 S 250 D $ 15.94 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/27/97 S 250 D $ 15.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/29/97 S 250 D $ 13.44 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/30/97 S 250 D $ 13.75 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/31/97 S 250 D $ 12.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 10/31/97 S 250 D $ 12.50 991,750 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 11/14/97 S 250 D $ 10.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 11/17/97 S 250 D $ 11.88 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 11/18/97 S 250 D $ 10.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 11/19/97 S 250 D $ 10.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 11/30/97 J-3 200,000 A I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 11/21/97 S 250 D $ 10.06 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 11/21/97 S 250 D $ 10.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 11/24/97 S 250 D $ 10.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 11/25/97 S 250 D $ 9.69 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 11/26/97 S 250 D $ 9.69 1,189,500 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/1/97 S 500 D $ 9.69 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/2/97 S 250 D $ 9.90 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/3/97 S 250 D $ 10.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/4/97 S 400 D $ 9.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/5/97 S 400 D $ 9.69 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>
9 of 12
<PAGE>
FORM 4 CONTINUED...
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 10549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
- --------------------------------------------------------------------------------
1 Name and Address |2 Issuer Name and Ticker or Trading Symbol
Reporting Person |
SEE JACKIE R. | HARVARD SCIENTIFIC CORP. HVSF
-----------------------------------|------------------------------------------
(Last) (First) (Middle) |4 Statement for
| Month/Year
100 N. Arlington Avenue, Suite 23P|
-----------------------------------| All months beginning 12/96 to 2/98
(Street) | which include all unreported shares
| exluded1from previously filed Form 4's
Reno Nevada (89501)|
-----------------------------------|
(City) (State) (Zip) |
|
- -------------------------------------------------------------------------------
<TABLE>
<CAPTION>
6.
4. 5. Owner-
Securities Acquired (A) or Amount of ship
3. Disposed of (D) Securities Form: 7.
Transaction (Instr. 3, 4 and 5) Beneficially Direct Nature of
2. Code ------------------------------- Owned at End (D) or Indirect
1. Transaction (Instr. 8) (A) of Month Indirect Beneficial
Title of Security Date ------------ Amount or Price (Instr. 3 (I) Ownership
(Instr. 3) (mm/dd/yy) Code V (D) and 4) (Instr.4) (Instr. 4)
====================================================================================================================================
Reference Legend:
*** All transactions have been restated to reflect the 1 for 10 reverse stock
split effective February 2, 1998.
*V Biosphere Technology Inc. ("BTI") is a shareholder of the issuer. The person
reporting may be deemed to beneficially own the shares of the issuer's
common stock, held by BTI.
*X Outstanding balances incorporates transactions reported on previous Form
4's.
*W The Anita Wassgren See Trust is a shareholder of the issuer. The reporting
person's spouse is the settler and trustee of the Trust and, accordingly,
the reporting person may be deemed to beneficially own the issuer's shares
held by the Trust.
J-1 Shares loaned, and it is expected they will be returned at a later date.
J-2 Shares issued in lieu of a legal settlement.
J-3 Shares issued in exchange for intellectual rights.
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C>
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/8/97 S 400 D $ 9.06 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/9/97 S 400 D $ 6.38 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/10/97 S 400 D $ 6.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/11/97 S 400 D $ 4.70 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/12/97 S 400 D $ 4.30 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/15/97 S 400 D $ 4.70 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/16/97 S 400 D $ 5.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/17/97 S 400 D $ 5.10 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/18/97 S 400 D $ 4.60 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/22/97 S 400 D $ 4.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/23/97 S 400 D $ 4.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/24/97 S 400 D $ 4.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/24/97 S 400 D $ 4.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/26/97 S 400 D $ 3.90 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/30/97 S 400 D $ 3.30 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/30/97 S 400 D $ 3.10 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/31/97 S 400 D $ 3.00 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 12/31/97 S 400 D $ 3.40 1,180,500 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/2/98 S 400 D $ 3.80 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/5/98 S 400 D $ 3.35 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/6/98 S 400 D $ 3.20 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/7/98 S 400 D $ 3.30 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/9/98 S 400 D $ 3.20 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/13/98 S 400 D $ 3.70 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/13/98 S 400 D $ 3.70 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/14/98 S 400 D $ 6.60 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>
10 of 12
<PAGE>
FORM 4 CONTINUED...
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 10549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
- --------------------------------------------------------------------------------
1 Name and Address |2 Issuer Name and Ticker or Trading Symbol
Reporting Person |
SEE JACKIE R. | HARVARD SCIENTIFIC CORP. HVSF
-----------------------------------|------------------------------------------
(Last) (First) (Middle) |4 Statement for
| Month/Year
100 N. Arlington Avenue, Suite 23P|
-----------------------------------| All months beginning 12/96 to 2/98
(Street) | which include all unreported shares
| exluded1from previously filed Form 4's
Reno Nevada (89501)|
-----------------------------------|
(City) (State) (Zip) |
|
- -------------------------------------------------------------------------------
<TABLE>
<CAPTION>
6.
4. 5. Owner-
Securities Acquired (A) or Amount of ship
3. Disposed of (D) Securities Form: 7.
Transaction (Instr. 3, 4 and 5) Beneficially Direct Nature of
2. Code ------------------------------- Owned at End (D) or Indirect
1. Transaction (Instr. 8) (A) of Month Indirect Beneficial
Title of Security Date ------------ Amount or Price (Instr. 3 (I) Ownership
(Instr. 3) (mm/dd/yy) Code V (D) and 4) (Instr.4) (Instr. 4)
====================================================================================================================================
Reference Legend:
*** All transactions have been restated to reflect the 1 for 10 reverse stock
split effective February 2, 1998.
*V Biosphere Technology Inc. ("BTI") is a shareholder of the issuer. The person
reporting may be deemed to beneficially own the shares of the issuer's
common stock, held by BTI.
*X Outstanding balances incorporates transactions reported on previous Form
4's.
*W The Anita Wassgren See Trust is a shareholder of the issuer. The reporting
person's spouse is the settler and trustee of the Trust and, accordingly,
the reporting person may be deemed to beneficially own the issuer's shares
held by the Trust.
J-1 Shares loaned, and it is expected they will be returned at a later date.
J-2 Shares issued in lieu of a legal settlement.
J-3 Shares issued in exchange for intellectual rights.
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C>
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/16/98 S 300 D $ 10.31 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/16/98 S 100 D $ 10.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/20/98 S 400 D $ 7.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/21/98 S 400 D $ 5.63 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/22/98 S 400 D $ 5.94 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/23/98 S 400 D $ 5.94 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/26/98 S 270 D $ 6.25 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/26/98 S 130 D $ 5.94 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/27/98 S 250 D $ 7.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/27/98 S 150 D $ 7.19 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/28/98 S 400 D $ 8.13 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/29/98 S 1,550 D $ 6.98 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/29/98 S 400 D $ 7.81 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/29/98 S 250 D $ 7.50 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 1/29/98 S 150 D $ 7.81 1,171,750 I Biosphere *V
- ------------------------------------------------------------------------------------------------------------------------------------
COMMON STOCK 2/3/98 A 790,139 A $ 3.16 D
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>
11 of 12
<PAGE>
FORM 4 (continued)
Table II -- Derivative Securities Acquired, Disposed of, or Beneficially
Owned (e.g., puts, calls, warrants, options, convertible securities)
================================================================================
<TABLE>
<CAPTION>
9. 10.
Number Owner-
of ship
2. Deriv- of
Conver- 5. 7. ative Deriv- 11.
sion Number of Title and Amount Secur- ative Nature
of Derivative 6. of Underlying 8. ities Secur- of
Exer- 4. Securities Date Securities Price Bene- ity: In-
cise 3. Trans- Acquired (A) Exercisable and (Instr. 3 and 4) of ficially Direct direct
Price Trans- action or Disposed Expiration Date ---------------- Deriv- Owned (D) or Bene-
1. of action Code of(D) (Month/Day/Year) Amount ative at End In- ficial
Title of Deriv- Date (Instr. (Instr. 3, ---------------- or Secur- of direct Owner-
Derivative ative (Month/ 8) 4 and 5) Date Expira- Number ity Month (I) ship
Security Secur- Day/ ------ ------------ Exer- tion of (Instr. (Instr. (Instr. (Instr.
(Instr. 3) ity Year) Code V (A) (D) cisable Date Title Shares 5) 4) 4) 4)
- ------------------------------------------------------------------------------------------------------------------------------------
<S> <C> <C> <C> <C> <C> <C> <C> <C> <C> <C> <C> <C> <C> <C>
RIGHT TO PURCHASE $6.26/ 2/3/98 J 296,302 Current 4/1/99 Common 296,302 0 296,302 D
$12.66 Stock
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
- ------------------------------------------------------------------------------------------------------------------------------------
====================================================================================================================================
</TABLE>
Explanation of Responses:
*** All the above transactions have been restated to reflect the 1 for 10
reverse stock split effective February 2, 1998.
*V Biosphere Technology Inc. ("BTI") is a shareholder of the issuer. The
person reporting may be deemed to beneficially own the shares of the
issuer's common stock, held by BTI.
*X Outstanding balances incorporates transactions reported on previous Form
4's.
*Z The lower price applies to the First 2/3 of the shares purchasable, the
higher price to the remaining 1/3.
/S/ Dr. Jackie R. See 4/6/98
- --------------------------------------------- -----------------------
**Signature of Reporting Person Date
** Intentional misstatements or omissions of facts constitute Federal
Criminal Violations.
See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed.
If space provided is insufficient, see Instruction 6 for procedures.
Alternatively, this Form is permitted to be submitted to the Commission
in electronic format at the option of the reporting person pursuant to
rule 101(b)(4) of Regulation S-T.
Potential persons who are to respond to the collection of information contained
in this form are not required to respond unless the form displays a currently
valid OMB Number.
Page 12 of 12
