BONE CARE INTERNATIONAL INC
S-3, EX-1.1, 2000-09-12
PHARMACEUTICAL PREPARATIONS
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                                                                     EXHIBIT 1.1

                         BONE CARE INTERNATIONAL, INC.

                              3,000,000 Shares/(1)/

                                  Common Stock

                             UNDERWRITING AGREEMENT
                             ----------------------


                                                             September ___, 2000


PRUDENTIAL SECURITIES INCORPORATED
U.S. BANCORP PIPER JAFFRAY INCORPORATED
As Representatives of the several Underwriters
c/o Prudential Securities Incorporated
One New York Plaza
New York, New York 10292

Ladies and Gentlemen:

          Bone Care International, Inc., a Wisconsin corporation (the
"Company"), hereby confirms its agreement with the several underwriters named in
Schedule I hereto (the "Underwriters"), for whom you have been duly authorized
to act as representatives (in such capacities, the "Representatives"), as set
forth below.  If you are the only Underwriters, all references herein to the
Representatives shall be deemed to be to the Underwriters.

     1.  Securities.  Subject to the terms and conditions herein contained, the
Company proposes to issue and sell to the several Underwriters an aggregate of
3,000,000 shares (the "Firm Securities") of the Company's common stock, without
par value ("Common Stock").  The Company also proposes to issue and sell to the
several Underwriters not more than 450,000 additional shares of Common Stock if
requested by the Representatives as provided in Section 3 of this Agreement.
Any and all shares of Common Stock to be purchased by the Underwriters pursuant
to such option are referred to herein as the "Option Securities", and the Firm
Securities and any Option Securities are collectively referred to herein as the
"Securities".

     2.  Representations and Warranties of the Company.  The Company represents
and warrants to, and agrees with, each of the several Underwriters that:

     (a) The Company meets the requirements for use of Form S-3 under the
Securities Act of 1933, as amended (the "Act").  A registration statement on
such Form (File No. 333-____) with respect to the Securities, including a
prospectus subject to completion, has been filed by the Company with the
Securities and Exchange Commission (the "Commission") under the Act, and

----------------------

/(1)/  Plus an option to purchase from Bone Care International, Inc., up to
       450,000 additional shares to cover over-allotments.
<PAGE>

one or more amendments to such registration statement may have been so filed.
After the execution of this Agreement, the Company will file with the Commission
either (i) if such registration statement, as it may have been amended, has been
declared by the Commission to be effective under the Act, either (A) if the
Company relies on Rule 434 under the Act, a Term Sheet (as hereinafter defined)
relating to the Securities, that shall identify the Preliminary Prospectus (as
hereinafter defined) that it supplements containing such information as is
required or permitted by Rules 434, 430A and 424(b) under the Act or (B) if the
Company does not rely on Rule 434 under the Act, a prospectus in the form most
recently included in an amendment to such registration statement (or, if no such
amendment shall have been filed, in such registration statement), with such
changes or insertions as are required by Rule 430A under the Act or permitted by
Rule 424(b) under the Act, and in the case of clause (i)(A) or (i)(B) of this
sentence as have been provided to and approved by the Representatives prior to
the execution of this Agreement, or (ii) if such registration statement, as it
may have been amended, has not been declared by the Commission to be effective
under the Act, an amendment to such registration statement, including a form of
prospectus, a copy of which amendment has been furnished to and approved by the
Representatives prior to the execution of this Agreement. The Company may also
file a related registration statement with the Commission pursuant to Rule
462(b) under the Act for the purpose of registering certain additional
Securities, which registration shall be effective upon filing with the
Commission. As used in this Agreement, the term "Original Registration
Statement" means the registration statement initially filed relating to the
Securities, as amended at the time when it was or is declared effective,
including (A) all financial schedules and exhibits thereto, any information
omitted therefrom pursuant to Rule 430A under the Act and included in the
Prospectus (as hereinafter defined); the term "Rule 462(b) Registration
Statement" means any registration statement filed with the Commission pursuant
to Rule 462(b) under the Act (including the Registration Statement and any
Preliminary Prospectus or Prospectus incorporated therein at the time such
Registration Statement becomes effective); the term "Registration Statement"
includes both the Original Registration Statement and any Rule 462(b)
Registration Statement; the term "Preliminary Prospectus" means each prospectus
subject to completion filed with such registration statement or any amendment
thereto (including the prospectus subject to completion, if any, included in the
Registration Statement or any amendment thereto at the time it was or is
declared effective); the term "Prospectus" means:

     (A) if the Company relies on Rule 434 under the Act, the Term Sheet
     relating to the Securities that is first filed pursuant to Rule 424(b)(7)
     under the Act, together with the Preliminary Prospectus identified therein
     that such Term Sheet supplements:

     (B) if the Company does not rely on Rule 434 under the Act, the prospectus
     first filed with the Commission pursuant to Rule 424(b) under the Act; or

     (C) if the Company does not rely on Rule 434 under the Act and if no
     prospectus is required to be filed pursuant to Rule 424(b) under the Act,
     the prospectus included in the Registration Statement, including, in the
     case of clauses (A), (B) or (C) of this sentence, all documents
     incorporated by reference therein filed under the Exchange Act; and the
     term "Term Sheet" means any term sheet that satisfies the requirements of
     Rule 434 under the Act.  Any reference in this Agreement to an "amendment
     or supplement" to any Preliminary Prospectus, the Prospectus or an
     "amendment" to any registration statement

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     (including the Registration Statement) shall be deemed to include any
     document incorporated by reference therein that is filed with the
     Commission under the Exchange Act after the date of such Preliminary
     Prospectus, Prospectus or registration statement, as the case may be; any
     reference herein to the "date" of a Prospectus that includes a Term Sheet
     shall mean the date of such Term Sheet. For purposes of the preceding
     sentence, any reference to the "effective date" of an amendment to a
     registration statement shall, if such amendment is effected by means of the
     filing with the Commission under the Exchange Act of a document
     incorporated by reference in such registration statement, be deemed to
     refer to the date on which such document was so filed with the Commission.

     (b) The Commission has not issued any order preventing or suspending the
use of any Preliminary Prospectus.  When any Preliminary Prospectus and any
amendment or supplement thereto was filed with the Commission, it (i) contained
all statements required to be stated therein in accordance with, and complied in
all material respects with the requirements of, the Act, the Exchange Act and
the respective rules and regulations of the Commission thereunder, and (ii) did
not include any untrue statement of a material fact or omit to state any
material fact necessary in order to make the statements therein, in the light of
the circumstances under which they were made, not misleading.  When the
Registration Statement or any amendment thereto was or is declared effective, it
(i) contained or will contain all statements required to be stated therein in
accordance with, and complied or will comply in all material respects with the
requirements of, the Act, the Exchange Act and the respective rules and
regulations of the Commission thereunder and (ii) did not or will not include
any untrue statement of a material fact or omit to state any material fact
necessary to make the statements therein not misleading.  When the Prospectus or
any Term Sheet that is a part thereof or any amendment or supplement to the
Prospectus is filed with the Commission pursuant to Rule 424(b) (or, if the
Prospectus or part thereof or such amendment or supplement is not required to be
so filed, when the Registration Statement or the amendment thereto containing
such amendment or supplement to the Prospectus was or is declared effective), on
the date when the Prospectus is otherwise amended or supplemented and on the
Firm Closing Date and any Option Closing Date (both as hereinafter defined), the
Prospectus, as amended or supplemented at any such time, (i) contained or will
contain all statements required to be stated therein in accordance with, and
complied or will comply in all material respects with the requirements of, the
Act, the Exchange Act and the respective rules and regulations of the Commission
thereunder and (ii) did not or will not include any untrue statement of a
material fact or omit to state any material fact necessary in order to make the
statements therein, in the light of the circumstances under which they were
made, not misleading.  The foregoing provisions of this paragraph (b) do not
apply to statements or omissions made in any Preliminary Prospectus, or any
amendment or supplement thereto, the Registration Statement, or any amendment
thereto or the Prospectus or any amendment or supplement thereto in reliance
upon and in conformity with written information furnished to the Company by any
Underwriter through the Representatives specifically for use therein.

     (c) If the Company has elected to rely on Rule 462(b) and the Rule 462(b)
Registration Statement has not been declared effective, (i) the Company has
filed a Rule 462(b) Registration Statement in compliance with, and that is
effective upon filing pursuant to, Rule 462(b) and has received confirmation of
its receipt; and (ii) the Company has given irrevocable instructions for
transmission of the applicable filing fee in connection with the filing of the
Rule

                                      -3-
<PAGE>

462(b) Registration Statement, in compliance with Rule 111 promulgated under the
Act, or the Commission has received payment of such filing fee.

     (d) The Company and each of its subsidiaries (the "subsidiaries") have been
duly organized and are validly existing as corporations in good standing under
the laws of their respective jurisdictions of incorporation and are duly
qualified to transact business as foreign corporations and are in good standing
under the laws of all other jurisdictions where the ownership or leasing of
their respective properties or the conduct of their respective businesses
requires such qualification, except where the failure to be so qualified does
not amount to a material liability or disability to the Company and its
subsidiaries, taken as a whole.

     (e) The Company and each of its subsidiaries have full power (corporate and
other) to own or lease their respective properties and conduct their respective
businesses as described in the Registration Statement or, if the Prospectus is
not in existence, the most recent Preliminary Prospectus; and the Company has
full power (corporate and other) to enter into this Agreement and to carry out
all the terms and provisions hereof to be carried out by it.

     (f) The issued shares of capital stock of each of the Company's
subsidiaries have been duly authorized and validly issued, are fully paid and
nonassessable and are owned beneficially by the Company free and clear of any
security interests, liens, encumbrances, equities or claims.

     (g) The Company has an authorized, issued and outstanding capitalization as
set forth in the Prospectus or, if the Prospectus is not in existence, the most
recent Preliminary Prospectus.  All of the issued shares of capital stock of the
Company have been duly authorized and validly issued and are fully paid and
nonassessable.  The Firm Securities and the Option Securities have been duly
authorized and at the Firm Closing Date or the related Option Closing Date (as
the case may be), after payment therefor in accordance herewith, will be validly
issued, fully paid and nonassessable.  No holders of outstanding shares of
capital stock of the Company are entitled as such to any preemptive or other
rights to subscribe for any of the Securities, and no holder of securities of
the Company has any right which has not been fully exercised or waived to
require the Company to register the offer or sale of any securities owned by
such holder under the Act in the public offering contemplated by this agreement.

     (h) The capital stock of the Company conforms to the description thereof
contained in the Prospectus (or, if the Prospectus is not in existence, the most
recent Preliminary Prospectus).

     (i) Except as disclosed in the Prospectus (or, if the Prospectus is not in
existence, the most recent Preliminary Prospectus), there are no outstanding (A)
securities or obligations of the Company or any of its subsidiaries convertible
into or exchangeable for any capital stock of the Company or any such
subsidiary, (B) warrants, rights or options to subscribe for or purchase from
the Company or any such subsidiary any such capital stock or any such
convertible or exchangeable securities or obligations, or (C) obligations of the
Company or any such subsidiary to issue any shares of capital stock, any such
convertible or exchangeable securities or obligations, or any such warrants,
rights or options.

                                      -4-
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     (j) The consolidated financial statements and schedules of the Company and
its consolidated subsidiaries included in the Registration Statement and the
Prospectus (or, if the Prospectus is not in existence, the most recent
Preliminary Prospectus) fairly present the financial position of the Company and
its consolidated subsidiaries and the results of operations and changes in
financial condition as of the dates and periods therein specified.  Such
financial statements and schedules have been prepared in accordance with
generally accepted accounting principles consistently applied throughout the
periods involved (except as otherwise noted therein).  The selected financial
data set forth under the caption "Selected Consolidated Financial Data" in the
Prospectus (or, if the Prospectus is not in existence, the most recent
Preliminary Prospectus) fairly present, on the basis stated in the Prospectus
(or such Preliminary Prospectus), the information included therein.

     (k) Each of KPMG Peat Marwick and Arthur Andersen LLP, who have certified
certain financial statements of the Company and its consolidated subsidiaries
and delivered their report with respect to the audited consolidated financial
statements and schedules included in the Registration Statement and the
Prospectus (or, if the Prospectus is not in existence, the most recent
Preliminary Prospectus), are independent public accountants as required by the
Act, the Exchange Act and the applicable rules and regulations thereunder.

     (l) The execution and delivery of this Agreement have been duly authorized
by the Company, and this Agreement has been duly executed and delivered by, and
is the valid and binding agreement of, the Company, enforceable against the
Company in accordance with its terms.

     (m) No legal or governmental proceedings are pending to which the Company
or any of its subsidiaries is a party or to which the property of the Company or
any of its subsidiaries is subject that are required to be described in the
Registration Statement or the Prospectus and are not described therein (or, if
the Prospectus is not in existence, the most recent Preliminary Prospectus), and
no such proceedings have been threatened against the Company or any of its
subsidiaries or with respect to any of their respective properties; and no
contract or other document is required to be described in the Registration
Statement or the Prospectus or to be filed as an exhibit to the Registration
Statement that is not described therein (or, if the Prospectus is not in
existence, the most recent Preliminary Prospectus), or filed as required.

     (n) The issuance, offering and sale of the Securities to the Underwriters
by the Company pursuant to this Agreement, the compliance by the Company with
the other provisions of this Agreement and the consummation of the other
transactions herein contemplated do not (i) require the consent, approval,
authorization, registration or qualification of or with any governmental
authority, except such as have been obtained, such as may be required under
state securities or blue sky laws and, if the registration statement filed with
respect to the Securities (as amended) is not effective under the Act as of the
time of execution hereof, such as may be required (and shall be obtained as
provided in this Agreement) under the Act, or (ii) conflict with or result in a
breach or violation of any of the terms and provisions of, or constitute a
default under, any indenture, mortgage, deed of trust, lease or other agreement
or instrument to which the Company or any of its subsidiaries is a party or by
which the Company or any of its subsidiaries or any of their respective
properties are bound, or the charter documents or by-laws

                                      -5-
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of the Company or any of its subsidiaries, or any statute or any judgment,
decree, order, rule or regulation of any court or other governmental authority
or any arbitrator applicable to the Company or any of its subsidiaries.

     (o) Subsequent to the respective dates as of which information is given in
the Registration Statement and the Prospectus (or if the Prospectus is not in
existence, the most recent Preliminary Prospectus), neither the Company nor any
of its subsidiaries has sustained any material loss or interference with their
respective businesses or properties from fire, flood, hurricane, accident or
other calamity, whether or not covered by insurance, or from any labor dispute
or any legal or governmental proceeding and there has not been any material
adverse change, or any development involving a prospective material adverse
change, in the condition (financial or otherwise), management, business
prospects, net worth, or results of operations of the Company or any of its
subsidiaries, except in each case as described in or contemplated by the
Prospectus (or, if the Prospectus is not in existence, the most recent
Preliminary Prospectus).

     (p) The Company has not, directly or indirectly, (i) taken any action
designed to cause or to result in, or that has constituted or which might
reasonably be expected to constitute, the stabilization or manipulation of the
price of any security of the Company to facilitate the sale or resale of the
Securities, or (ii) since the filing of the Registration Statement (A) sold, bid
for, purchased, or paid anyone any compensation for soliciting purchases of the
Securities or (B) paid or agreed to pay to any person any compensation for
soliciting another to purchase any other securities of the Company.

     (q) The Company has not distributed and, prior to the later of (i) the
Closing Date and (ii) the completion of the distribution of the Securities, will
not distribute any offering material in connection with the offering and sale of
the Securities other than the Registration Statement or any amendment thereto,
any Preliminary Prospectus or the Prospectus or any amendment or supplement
thereto, or other materials, if any permitted by the Act.

     (r) Subsequent to the respective dates as of which information is given in
the Registration Statement and the Prospectus (or, if the Prospectus is not in
existence, the most recent Preliminary Prospectus), (1) the Company and its
subsidiaries have not incurred any material liability or obligation, direct or
contingent, nor entered into any material transaction not in the ordinary course
of business; (2) the Company has not purchased any of its outstanding capital
stock, nor declared, paid or otherwise made any dividend or distribution of any
kind on its capital stock; and (3) there has not been any material change in the
capital stock, short-term debt or long-term debt of the Company and its
consolidated subsidiaries, except in each case as described in or contemplated
by the Prospectus (or, if the Prospectus is not in existence, the most recent
Preliminary Prospectus).

     (s) The Company and each of its subsidiaries have good and marketable title
in fee simple to all items of real property and marketable title to all personal
property owned by each of them, in each case free and clear of any security
interests, liens, encumbrances, equities, claims and other defects, except such
as do not materially and adversely affect the value of such property and do not
interfere with the use made or proposed to be made of such property by the
Company or any of its subsidiaries, and any real property and buildings held
under lease by the

                                      -6-
<PAGE>

Company or any of its subsidiaries are held under valid, subsisting and
enforceable leases, with such exceptions as are not material and do not
interfere with the use made or proposed to be made of such property and
buildings by the Company or any of its subsidiaries, in each case except as
described in or contemplated by the Prospectus (or, if the Prospectus is not in
existence, the most recent Preliminary Prospectus).

     (t) No labor dispute with the employees of the Company or any of its
subsidiaries exists or is threatened or imminent that could result in a material
adverse change in the condition (financial or otherwise), business prospects,
net worth or results of operations of the Company and its subsidiaries, except
as described in or contemplated by the Prospectus (or, if the Prospectus is not
in existence, the most recent Preliminary Prospectus).

     (u) The Company and its subsidiaries own, license, or possess, or can
acquire on reasonable terms, all material patents, patent applications,
trademarks, service marks, trade names, licenses, copyrights and proprietary or
other confidential information currently employed by them in connection with
their respective businesses, and neither the Company nor any of its subsidiaries
has received any notice of infringement of or conflict with asserted rights of
any third party with respect to any of the foregoing which, singly or in the
aggregate, if the subject of an unfavorable decision, ruling or finding, would
result in a material adverse change in the condition (financial or otherwise),
business prospects, net worth or results of operations of the Company and its
subsidiaries, except as described in or contemplated by the Prospectus (or, if
the Prospectus is not in existence, the most recent Preliminary Prospectus).

     (v) The Company and each of its subsidiaries are insured by insurers of
recognized financial responsibility against such losses and risks and in such
amounts as are prudent and customary in the businesses in which they are
engaged; neither the Company nor any such subsidiary has been refused any
insurance coverage sought or applied for; and neither the Company nor any such
subsidiary has any reason to believe that it will not be able to renew its
existing insurance coverage as and when such coverage expires or to obtain
similar coverage from similar insurers as may be necessary to continue its
business at a cost that would not materially and adversely affect the condition
(financial or otherwise), business prospects, net worth or results of operations
of the Company and its subsidiaries, except as described in or contemplated by
the Prospectus (or, if the Prospectus is not in existence, the most recent
Preliminary Prospectus).

     (w) No subsidiary of the Company is currently prohibited, directly or
indirectly, from paying any dividends to the Company, from making any other
distribution on such subsidiary's capital stock, from repaying to the Company
any loans or advances to such subsidiary from the Company or from transferring
any of such subsidiary's property or assets to the Company or any other
subsidiary of the Company, except as described in or contemplated by the
Prospectus (or, if the Prospectus is not in existence, the most recent
Preliminary Prospectus).

     (x) The Company and its subsidiaries possess all certificates,
authorizations and permits issued by the appropriate federal, state or foreign
regulatory authorities necessary to conduct their respective businesses, and
neither the Company nor any such subsidiary has received any notice of
proceedings relating to the revocation or modification of any such

                                      -7-
<PAGE>

certificate, authorization or permit which, singly or in the aggregate, if the
subject of an unfavorable decision, ruling or finding, would result in a
material adverse change in the condition (financial or otherwise), business
prospects, net worth or results of operations of the Company and its
subsidiaries, except as described in or contemplated by the Prospectus (or, if
the Prospectus is not in existence, the most recent Preliminary Prospectus).

     (y) The Company will conduct its operations in a manner that will not
subject it to registration as an investment company under the Investment Company
Act of 1940, as amended, and this transaction will not cause the Company to
become an investment company subject to registration under such Act.

     (z) The Company has filed all foreign, federal, state and local tax returns
that are required to be filed or has requested extensions thereof (except in any
case in which the failure so to file would not have a material adverse effect on
the Company and its subsidiaries) and has paid all taxes required to be paid by
it and any other assessment, fine or penalty levied against it, to the extent
that any of the foregoing is due and payable, except for any such assessment,
fine or penalty that is currently being contested in good faith or as described
in or contemplated by the Prospectus (or, if the Prospectus is not in existence,
the most recent Preliminary Prospectus).

     (aa) Neither the Company nor any of its subsidiaries is in violation of any
federal or state law or regulation relating to occupational safety and health or
to the storage, handling or transportation of hazardous or toxic materials and
the Company and its subsidiaries have received all permits, licenses or other
approvals required of them under applicable federal and state occupational
safety and health and environmental laws and regulations to conduct their
respective businesses, and the Company and each such subsidiary is in compliance
with all terms and conditions of any such permit, license or approval, except
any such violation of law or regulation, failure to receive required permits,
licenses or other approvals or failure to comply with the terms and conditions
of such permits, licenses or approvals which would not, singly or in the
aggregate, result in a material adverse change in the condition (financial or
otherwise), business prospects, net worth or results of operations of the
Company and its subsidiaries, except as described in or contemplated by the
Prospectus (or, if the Prospectus is not in existence, the most recent
Preliminary Prospectus).

     (bb) Each certificate signed by any officer of the Company and delivered to
the Representatives or counsel for the Underwriters shall be deemed to be a
representation and warranty by the Company to each Underwriter as to the matters
covered thereby.

     (cc) Except for the shares of capital stock of each of the subsidiaries
owned by the Company and such subsidiaries, neither the Company nor any such
subsidiary owns any shares of stock or any other equity securities of any
corporation or has any equity interest in any firm, partnership, association or
other entity, except as described in or contemplated by the Prospectus (or, if
the Prospectus is not in existence, the most recent Preliminary Prospectus).

     (dd) There are no holders of securities of the Company, who, by reason of
the filing of the Registration Statement, have the right (and have not waived
such right) to request the

                                      -8-
<PAGE>

Company to register under the Act, or to include in the Registration Statement,
securities held by them.

     (ee) The Company and each of its subsidiaries maintain a system of internal
accounting controls sufficient to provide reasonable assurance that (1)
transactions are executed in accordance with management's general or specific
authorizations; (2) transactions are recorded as necessary to permit preparation
of financial statements in conformity with generally accepted accounting
principles and to maintain asset accountability; (3) access to assets is
permitted only in accordance with management's general or specific
authorization; and (4) the recorded accountability for assets is compared with
the existing assets at reasonable intervals and appropriate action is taken with
respect to any differences.

     (ff) No default exists, and no event has occurred which, with notice or
lapse of time or both, would constitute a default in the due performance and
observance of any term, covenant or condition of any indenture, mortgage, deed
of trust, lease or other agreement or instrument to which the Company or any of
its subsidiaries is a party or by which the Company or any of its subsidiaries
or any of their respective properties is bound or may be affected in any
material adverse respect with regard to property, business or operations of the
Company and its subsidiaries.

     (gg) Neither the Company nor any of its subsidiaries is in violation of any
healthcare law, ordinance, administrative or governmental rule or regulation
applicable to the Company or its subsidiaries, including, without limitation,
those relating to product testing, marketing approvals and reimbursement by
government agencies or third-party payors.

     3.  Purchase, Sale and Delivery of the Securities.  (a) On the basis of the
representations, warranties, agreements and covenants herein contained and
subject to the terms and conditions herein set forth, the Company agrees to
issue and sell to each of the Underwriters, and each of the Underwriters,
severally and not jointly, agrees to purchase from the Company, at a purchase
price of $_______ per share, the number of Firm Securities set forth opposite
the name of such Underwriter in Schedule I hereto.  One or more certificates in
definitive form for the Firm Securities that the several Underwriters have
agreed to purchase hereunder, and in such denomination or denominations and
registered in such name or names as the Representatives request upon notice to
the Company at least 48 hours prior to the Firm Closing Date, shall be delivered
by or on behalf of the Company to the Representatives for the respective
accounts of the Underwriters, against payment by or on behalf of the
Underwriters of the purchase price therefor by wire transfer in same-day funds
(the "Wired Funds") to the account of the Company.  Such delivery of and payment
for the Firm Securities shall be made at the offices of Stroock & Stroock &
Lavan LLP, 180 Maiden Lane, New York, New  York 10038 at 9:30 A.M., New York
time, on _________, 2000, or at such other place, time or date as the
Representatives and the Company may agree upon or as the Representatives may
determine pursuant to Section 9 hereof, such time and date of delivery against
payment being herein referred to as the "Firm Closing Date".  The Company will
make such certificate or certificates for the Firm Securities available for
checking and packaging by the Representatives at the offices in New York, New
York of the Company's transfer agent or registrar or of Prudential Securities
Incorporated at least 24 hours prior to the Firm Closing Date.

                                      -9-
<PAGE>

     (b) For the purpose of covering any over-allotments in connection with the
distribution and sale of the Firm Securities as contemplated by the Prospectus,
the Company hereby grants to the several Underwriters an option to purchase,
severally and not jointly, the Option Securities.  The purchase price to be paid
for any Option Securities shall be the same price per share as the price per
share for the Firm Securities set forth above in paragraph (a) of this Section
3.  The option granted hereby may be exercised as to all or any part of the
Option Securities from time to time within thirty days after the date of the
Prospectus (or, if such 30th day shall be a Saturday or Sunday or a holiday, on
the next business day thereafter when the New York Stock Exchange is open for
trading).  The Underwriters shall not be under any obligation to purchase any of
the Option Securities prior to the exercise of such option.  The Representatives
may from time to time exercise the option granted hereby by giving notice in
writing or by telephone (confirmed in writing) to the Company setting forth the
aggregate number of Option Securities as to which the several Underwriters are
then exercising the option and the date and time for delivery of and payment for
such Option Securities.  Any such date of delivery shall be determined by the
Representatives but shall not be earlier than two business days or later than
five business days after such exercise of the option and, in any event, shall
not be earlier than the Firm Closing Date.  The time and date set forth in such
notice, or such other time on such other date as the Representatives and the
Company may agree upon or as the Representatives may determine pursuant to
Section 9 hereof, is herein called the "Option Closing Date" with respect to
such Option Securities.  Upon exercise of the option as provided herein, the
Company shall become obligated to sell to each of the several Underwriters, and,
subject to the terms and conditions herein set forth, each of the Underwriters
(severally and not jointly) shall become obligated to purchase from the Company,
the same percentage of the total number of the Option Securities as to which the
several Underwriters are then exercising the option as such Underwriter is
obligated to purchase of the aggregate number of Firm Securities, as adjusted by
the Representatives in such manner as they deem advisable to avoid fractional
shares.  If the option is exercised as to all or any portion of the Option
Securities, one or more certificates in definitive form for such Option
Securities, and payment therefor, shall be delivered on the related Option
Closing Date in the manner, and upon the terms and conditions, set forth in
paragraph (a) of this Section 3, except that reference therein to the Firm
Securities and the Firm Closing Date shall be deemed, for purposes of this
paragraph (b), to refer to such Option Securities and Option Closing Date,
respectively.

     (c) The Company hereby acknowledges that the wire transfer by or on behalf
of the Underwriters of the purchase price for any Securities does not constitute
closing of a purchase and sale of the Securities.  Only execution and delivery
of a receipt for Securities by the Underwriters indicates completion of the
closing of a purchase of the Securities from the Company.  Furthermore, in the
event that the Underwriters wire funds to the Company prior to the completion of
the closing of a purchase of Securities, the Company hereby acknowledges that
until the Underwriters execute and deliver a receipt for the Securities, by
facsimile or otherwise, the Company will not be entitled to the Wired Funds and
shall return the Wired Funds to the Underwriters as soon as practicable (by wire
transfer of same-day funds) upon demand.  In the event that the closing of a
purchase of Securities is not completed and the Wired Funds are not returned by
the Company to the Underwriters on the same day the Wired Funds were received by
the Company, the Company agrees to pay to the Underwriters in respect of each
day the Wired

                                      -10-
<PAGE>

Funds are not returned by it, in same-day funds, interest on the amount of such
Wired Funds in an amount representing the Underwriters' cost of financing as
reasonably determined by Prudential Securities Incorporated.

     (d) It is understood that any of you, individually and not as one of the
Representatives, may (but shall not be obligated to) make payment on behalf of
any Underwriter or Underwriters for any of the Securities to be purchased by
such Underwriter or Underwriters.  No such payment shall relieve such
Underwriter or Underwriters from any of its or their obligations hereunder.

     4.  Offering by the Underwriters.  Upon your authorization of the release
of the Firm Securities, the several Underwriters propose to offer the Firm
Securities for sale to the public upon the terms set forth in the Prospectus.

     5.  Covenants of the Company.  The Company covenants and agrees with each
of the Underwriters that:

     (a) The Company will use its best efforts to cause the Registration
Statement, if not effective at the time of execution of this Agreement, and any
amendments thereto to become effective as promptly as possible.  If required,
the Company will file the Prospectus or any Term Sheet that constitutes a part
thereof and any amendment or supplement thereto with the Commission in the
manner and within the time period required by Rules 434 and 424(b) under the
Act.  During any time when a prospectus relating to the Securities is required
to be delivered under the Act and the Company (i) will comply with all
requirements imposed upon it by the Act, the Exchange Act and the respective
rules and regulations of the Commission thereunder to the extent necessary to
permit the continuance of sales of or dealings in the Securities in accordance
with the provisions hereof and of the Prospectus, as then amended or
supplemented, and (ii) will not file with the Commission the prospectus or the
amendment referred to in the second sentence of Section 2(a) hereof, any
amendment or supplement to such prospectus or any amendment to the Registration
Statement or any Rule 462(b) Registration Statement of which the Representatives
shall not previously have been advised and furnished with a copy for a
reasonable period of time prior to the proposed filing and as to which filing
the Representatives shall not have given their consent.  The Company will
prepare and file with the Commission, in accordance with the rules and
regulations of the Commission, promptly upon request by the Representatives or
counsel for the Underwriters, any amendments to the Registration Statement or
amendments or supplements to the Prospectus that may be necessary or advisable
in connection with the distribution of the Securities by the several
Underwriters, and will use its best efforts to cause any such amendment to the
Registration Statement to be declared effective by the Commission as promptly as
possible.  The Company will advise the Representatives, promptly after receiving
notice thereof, of the time when the Registration Statement or any amendment
thereto has been filed or declared effective or the Prospectus or any amendment
or supplement thereto has been filed and will provide evidence satisfactory to
the Representatives of each such filing or effectiveness.

     (b) The Company will advise the Representatives, promptly after receiving
notice or obtaining knowledge thereof, of (i) the issuance by the Commission of
any stop order suspending

                                      -11-
<PAGE>

the effectiveness of the Original Registration Statement or any Rule 462(b)
Registration Statement or any post-effective amendment thereto or any order
directed at any document incorporated by reference in the Registration Statement
preventing or suspending the use of any Preliminary Prospectus or the Prospectus
or any amendment or supplement thereto, (ii) the suspension of the qualification
of the Securities for offering or sale in any jurisdiction, (iii) the
institution, threatening or contemplation of any proceeding for any such purpose
or (iv) any request made by the Commission for amending the Original
Registration Statement or any Rule 462(b) Registration Statement, for amending
or supplementing any Preliminary Prospectus or the Prospectus or for additional
information. The Company will use its best efforts to prevent the issuance of
any such stop order and, if any such stop order is issued, to obtain the
withdrawal thereof as promptly as possible.

     (c) The Company will cooperate, when and as requested by the
Representatives, in connection with the qualification of the Securities for
offering and sale under the securities or blue sky laws of such jurisdictions as
the Representatives may designate and will continue such qualifications in
effect for as long as may be necessary to complete the distribution of the
Securities, provided, however, that in connection therewith the Company shall
not be required to qualify as a foreign corporation or to execute a general
consent to service of process in any jurisdiction.

     (d) If, at any time prior to the later of (i) the final date when a
prospectus relating to the Securities is required to be delivered under the Act
or (ii) the Option Closing Date, any event occurs as a result of which the
Prospectus, as then amended or supplemented, would include any untrue statement
of a material fact or omit to state a material fact necessary in order to make
the statements therein, in the light of the circumstances under which they were
made, not misleading, or if for any other reason it is necessary at any time to
amend or supplement the Prospectus to comply with the Act, the Exchange Act or
the respective rules or regulations of the Commission thereunder, the Company
will promptly notify the Representatives thereof and, subject to Section 5(a)
hereof, will prepare and file with the Commission, at the Company's expense, an
amendment to the Registration Statement or an amendment or supplement to the
Prospectus that corrects such statement or omission or effects such compliance.

     (e) The Company will, without charge, provide (i) to the Representatives
and to counsel for the Underwriters a signed copy of the Original Registration
Statement filed with respect to the Securities and each amendment thereto (in
each case including exhibits thereto), (ii) to each other Underwriter, a
conformed copy of such registration statement or any Rule 462(b) Registration
Statement and each amendment thereto (in each case without exhibits thereto) and
(iii) so long as a prospectus relating to the Securities is required to be
delivered under the Act, as many copies of each Preliminary Prospectus or the
Prospectus or any amendment or supplement thereto as the Representatives may
reasonably request; without limiting the application of clause (iii) of this
sentence, the Company, not later than (A) 6:00 P.M., New York City time, on the
date of determination of the public offering price, if such determination
occurred at or prior to 10:00 A.M., New York City time on such date or (B) 2:00
P.M., New York City time, on the business day following the date of
determination of the public offering price, if such determination occurred after
10:00 A.M., New York City time, on such date, will deliver to the Underwriters,
without charge, as many copies of the Prospectus and any

                                      -12-
<PAGE>

amendment or supplement thereto as the Representatives may reasonably request
for purposes of confirming orders that are expected to settle on the Firm
Closing Date.

     (f) The Company, as soon as practicable, will make generally available to
its securityholders and to the Representatives a consolidated earnings statement
of the Company and its subsidiaries that satisfies the provisions of Section
11(a) of the Act and Rule 158 thereunder.

     (g) The Company will apply the net proceeds from the sale of the Securities
as set forth under "Use of Proceeds" in the Prospectus.

     (h) The Company will not, directly or indirectly, without the prior written
consent of Prudential Securities Incorporated, on behalf of the Underwriters,
offer, sell, offer to sell, contract to sell, pledge, grant any option to
purchase or otherwise sell or dispose (or announce any offer, sale, offer of
sale, contract of sale, pledge, grant of any option to purchase or other sale or
disposition) of any shares of Common Stock or any securities convertible into,
or exchangeable or exercisable for, shares of Common Stock for a period of 90
days after the date hereof, except pursuant to this Agreement and except for
issuances pursuant to the exercise of employee stock options outstanding on the
date hereof, pursuant to the Company's dividend reinvestment plan or pursuant to
the terms of convertible securities of the Company outstanding on the date
hereof.

     (i) The Company will not, directly or indirectly, (i) take any action
designed to cause or to result in, or that constitutes or which might reasonably
be expected to constitute, the stabilization or manipulation of the price of any
security of the Company to facilitate the sale or resale of the Securities or
(ii) (A) sell, bid for, purchase, or pay anyone any compensation for soliciting
purchases of, the Securities or (B) pay or agree to pay to any person any
compensation for soliciting another to purchase any other securities of the
Company.

     (j) The Company will obtain the agreements described in Section 7(f) hereof
prior to the Firm Closing Date.

     (k) If at any time during the 25-day period after the Registration
Statement becomes effective or the period prior to the Option Closing Date, any
rumor, publication or event relating to or affecting the Company shall occur as
a result of which in your opinion the market price of the Common Stock has been
or is likely to be materially affected (regardless of whether such rumor,
publication or event necessitates a supplement to or amendment of the
Prospectus, the Company will, after notice from you advising the Company to the
effect set forth above, forthwith prepare, consult with you concerning the
substance of and dissemination of a press release or other public statement,
reasonably satisfactory to you, responding to or commenting on such rumor,
publication or event.

     (l) If the Company elects to rely on Rule 462(b), the Company shall both
file a Rule 462(b) Registration Statement with the Commission in compliance with
Rule 462(b) and pay the applicable fees in accordance with Rule 111 promulgated
under the Act by the earlier of (i) 10:00 P.M. Eastern time on the date of this
Agreement and (ii) the time confirmations are sent or given, as specified by
Rule 462(b)(2).

                                      -13-
<PAGE>

     (m) The Company will cause the Securities to be duly included for quotation
on The Nasdaq Stock Market's National Market (the "Nasdaq National Market")
prior to the Firm Closing Date.  The Company will use its best efforts to cause
the Securities to remain included for quotation on the Nasdaq National Market
following the Firm Closing Date and until the earliest of three years after the
date hereof, the date when the Company is no longer subject to the reporting
requirements of the Exchange Act or the date the Securities are listed on a
national securities exchange.

     6.  Expenses.  The Company will pay all costs and expenses incident to the
performance of its obligations under this Agreement, whether or not the
transactions contemplated herein are consummated or this Agreement is terminated
pursuant to Section 11 hereof, including all costs and expenses incident to (i)
the printing or other production of documents with respect to the transactions,
including any costs of printing the Original Registration Statement filed with
respect to the Securities and any amendment thereto, any Rule 462(b)
Registration Statement, any Preliminary Prospectus and the Prospectus and any
amendment or supplement thereto, this Agreement and any blue sky memoranda, (ii)
all arrangements relating to the delivery to the Underwriters of copies of the
foregoing documents, (iii) the fees and disbursements of the counsel,
accountants and any other experts or advisors retained by the Company, (iv)
preparation, issuance and delivery to the Underwriters of any certificates
evidencing the Securities, including transfer agent's and registrar's fees, (v)
the qualification of the Securities under state securities and blue sky laws,
including filing fees and fees and disbursements of counsel for the Underwriters
relating thereto, (vi) the filing fees of the Commission and the National
Association of Securities Dealers, Inc. relating to the Securities, (vii) the
quotation of the Securities on the Nasdaq National Market, (viii) meetings with
prospective investors in the Securities (other than as shall have been
specifically approved by the Representatives to be paid for by the Underwriters)
and (ix) advertising relating to the offering of the Securities (other than
shall have been specifically approved by the Representatives to be paid for by
the Underwriters).  If the sale of the Securities provided for herein is not
consummated because any condition to the obligations of the Underwriters set
forth in Section 7 hereof is not satisfied, because this Agreement is terminated
pursuant to Section 11 hereof or because of any failure, refusal or inability on
the part of the Company to perform all obligations and satisfy all conditions on
its part to be performed or satisfied hereunder other than by reason of a
default by any of the Underwriters, the Company will reimburse the Underwriters
severally upon demand for all out-of-pocket expenses (including fees and
disbursements of counsel) that shall have been incurred by them in connection
with the proposed purchase and sale of the Securities.  The Company shall not in
any event be liable to any of the Underwriters for the loss of anticipated
profits from the transactions covered by this Agreement.

     7.  Conditions of the Underwriters' Obligations.  The obligations of the
several Underwriters to purchase and pay for the Firm Securities shall be
subject, in the Representatives' sole discretion, to the accuracy of the
representations and warranties of the Company contained herein as of the date
hereof and as of the Firm Closing Date, as if made on and as of the Firm Closing
Date, to the accuracy of the statements of the Company's officers made pursuant
to the provisions hereof, to the performance by the Company of its covenants and
agreements hereunder and to the following additional conditions:

                                      -14-
<PAGE>

     (a) If the Original Registration Statement or any amendment thereto filed
prior to the Firm Closing Date has not been declared effective as of the time of
execution hereof, the Original Registration Statement or such amendment and, if
the Company has elected to rely upon Rule 462(b), the Rule 462(b) Registration
Statement shall have become effective not later than the earlier of (i) 11:00
A.M., New York City time, on the date on which the amendment to the Original
Registration Statement filed with respect to the Securities or to the
Registration Statement, as the case may be, containing information regarding the
initial public offering price of the Securities has been filed with the
Commission and (ii) the time confirmations are sent or given as specified by
Rule 462(b)(2), or with respect to the Original Registration Statement, or such
later time and date as shall have been consented to by the Representatives; if
required, the Prospectus or any Term Sheet that constitutes a part thereof and
any amendment or supplement thereto shall have been filed with the Commission in
the manner and within the time period required by Rules 434 and 424(b) under the
Act; no stop order suspending the effectiveness of the Registration Statement or
any post-effective amendment thereto and no order directed at any document
incorporated by reference in the Registration Statement or the Prospectus or any
amendment or supplement thereto shall have been issued and no proceedings for
that purpose shall have been instituted or threatened or, to the knowledge of
the Company or the Representatives, shall be contemplated by the Commission; and
the Company shall have complied with any request of the Commission for
additional information (to be included in the Registration Statement or the
Prospectus or otherwise).

     (b) The Representatives shall have received an opinion, dated the Firm
Closing Date, of Sidley & Austin, counsel for the Company, to the effect that:

          (i) the Company and each of its subsidiaries listed in Exhibit 21 of
     the Registration Statement (Schedule 2 hereto) have been duly incorporated
     and are validly existing as corporations in good standing under the laws of
     their respective jurisdictions of incorporation and are duly qualified to
     transact business as foreign corporations and are in good standing under
     the laws of all other jurisdictions where the ownership or leasing of their
     respective properties or the conduct of their respective businesses
     requires such qualification, except where the failure to be so qualified
     does not amount to a material liability or disability to the Company and
     the subsidiaries, taken as a whole;

          (ii) the Company and each of the subsidiaries have full corporate
     power to own or lease their respective properties and conduct their
     respective businesses as described in the Registration Statement and the
     Prospectus and the Company has corporate power to enter into this Agreement
     and to carry out all the terms and provisions hereof and thereof to be
     carried out by it;

          (iii) all of the issued shares of capital stock of the Company and the
     subsidiaries have been duly authorized and validly issued and are fully
     paid and nonassessable; have been issued in compliance with all applicable
     federal and state securities laws and were not issued in violation of or
     subject to any preemptive rights or other rights to subscribe for or
     purchase securities the Firm Securities have been duly authorized by all
     necessary corporate action of the Company and, when issued and

                                      -15-
<PAGE>

     delivered to and paid for by the Underwriters pursuant to this Agreement,
     will be validly issued, fully paid and nonassessable; the Securities have
     been duly included for trading on the Nasdaq National Market; no holders of
     outstanding shares of capital stock of the Company are entitled as such to
     any preemptive or other rights to subscribe for any of the Securities; and
     no holders of securities of the Company are entitled to have such
     securities registered under the Registration Statement;

          (iv) the Company has an authorized, issued and outstanding
     capitalization as set forth in the Prospectus;

          (v) the statements set forth under the heading "Description of Capital
     Stock" in the Prospectus and, insofar as such statements purport to
     summarize certain provisions of the capital stock of the Company, provide a
     fair summary of such provisions; and the statements set forth under the
     headings "Business-Government Regulation" and "Business-Legal Proceedings"
     in the Prospectus insofar as such statements constitute a summary of the
     legal matters, documents or proceedings referred to therein, provide a fair
     summary of such legal matters, documents and proceedings;

          (vi) the execution and delivery of this Agreement have been duly
     authorized by all necessary corporate action of the Company and this
     Agreement has been duly executed and delivered by the Company;

          (vii) no legal or governmental proceedings are pending to which the
     Company or any of the subsidiaries is a party or to which the property of
     the Company or any of the subsidiaries is subject that are required to be
     described in the Registration Statement or the Prospectus and are not
     described therein, and, to the best knowledge of such counsel, no such
     proceedings have been threatened against the Company or any of the
     subsidiaries or with respect to any of their respective properties; and no
     contract or other document is required to be described in the Registration
     Statement, the Prospectus or to be filed as an exhibit to the Registration
     Statement that is not described therein or filed as required;

          (viii) the issuance, offering and sale of the Securities to the
     Underwriters by the Company pursuant to this Agreement, the compliance by
     the Company with the other provisions of this Agreement and the
     consummation of the other transactions herein contemplated do not (A)
     require the consent, approval, authorization, registration or qualification
     of or with any governmental authority, except such as have been obtained
     and such as may be required under state securities or blue sky laws, or (B)
     conflict with or result in a breach or violation of any of the terms and
     provisions of, or constitute a default under, any indenture, mortgage, deed
     of trust, lease or other agreement or instrument, known to such counsel, to
     which the Company or any of the subsidiaries is a party or by which the
     Company or any of the subsidiaries or any of their respective properties
     are bound, or the charter documents or by-laws of the Company or any
     statute or any judgment, decree, order, rule or regulation of any court or
     other governmental authority or any arbitrator known to such counsel and
     applicable to the Company or any of the subsidiaries;

                                      -16-
<PAGE>

          (ix) the Registration Statement is effective under the Act; any
     required filing of the Prospectus, or any Term Sheet that constitutes a
     part thereof has been made in the manner and within the time period
     required by Rules 434 and 424(b); and, no stop order suspending the
     effectiveness of the Registration Statement or any post-effective amendment
     thereto and no order directed at any document incorporated by reference in
     the Registration Statement or the Prospectus or any amendment or supplement
     thereto has been issued and no proceedings for that purpose have been
     instituted or threatened or, to the best knowledge of such counsel, are
     contemplated by the Commission;

          (x) the Original Registration Statement filed with respect to the
     Securities and each amendment thereto, any Rule 462(b) Registration
     Statement and the Prospectus (in each case, including the documents
     incorporated by reference therein but not including the financial
     statements and other financial information contained therein, as to which
     such counsel need express no opinion) comply as to form in all material
     respects with the applicable requirements of the Act, the Exchange Act and
     the respective rules and regulations of the Commission thereunder;

          (xi) if the Company elects to rely on Rule 434, the Prospectus is not
     "materially different," as such term is used in Rule 434, from the
     prospectus included in the Registration Statement at the time of its
     effectiveness or any effective post-effective amendment thereto (including
     such information that is permitted to be omitted pursuant to Rule 430A).

          Such counsel shall also state that they have no reason to believe that
     the Registration Statement, as of its effective date, contained any untrue
     statement of a material fact or omitted to state any material fact required
     to be stated therein or necessary to make the statements therein not
     misleading or that the Prospectus as of its date or the date of such
     opinion, included or includes any untrue statement of a material fact or
     omitted or omits to state a material fact necessary in order to make the
     statements therein, in the light of the circumstances under which they were
     made, not misleading;

          (xii) the Company is not subject to registration as an investment
     company under the Investment Company Act of 1940, as amended, and the
     offering and use of the proceeds therefrom as described in the Prospectus
     under the heading "Use of Proceeds" will not cause the Company to become an
     investment company under the Investment Company Act;

          (xiii) to such counsel's knowledge, neither the Company nor any of its
     subsidiaries is in violation of any federal or state law or regulation
     relating to the occupational safety and health or to the storage, handling
     or transportation of hazardous or toxic materials and the Company and each
     of the subsidiaries has received all permits, licenses or other approvals
     required of them under applicable federal and state occupational safety and
     health and environmental laws and regulations to conduct their respective
     businesses, and the Company and each of the subsidiaries are in compliance
     with all terms and conditions of any such permit, license or approval,
     except any such violation of law or regulation, failure to receive required
     permits, licenses or other

                                      -17-
<PAGE>

     approvals or failure to comply with the terms and conditions of such
     permits, licenses or approvals which would not, singly or in the aggregate,
     result in a material adverse change in the condition (financial or
     otherwise), business prospects, net worth or results of operations of the
     Company and the subsidiaries, except as described in the Prospectus;

          (xiv) there are no holders of securities of the Company, who, by
     reason of the filing of the Registration Statement, have the right (and
     have not waived such right) to request the Company to register under the
     Act, or to include in the Registration Statement, securities held by them;
     and

          (xv) to such counsel's knowledge, neither the Company nor the
     subsidiaries is in violation of any healthcare law, ordinance,
     administrative or governmental rule or regulation applicable to the Company
     or the subsidiaries, including, without limitation, those relating to
     product testing, marketing approvals and reimbursement by government
     agencies or third-party payors.

     In rendering any such opinion, such counsel may rely, as to matters of
fact, to the extent such counsel deems proper, on certificates of responsible
officers of the Company and its subsidiaries and public officials, provided that
copies of any such statements or certificates shall be delivered to counsel to
the Underwriters.  Such counsel shall also state that such counsel has
participated in conferences with officers and representatives of the Company,
representatives of the independent public accountants of the Company and the
Representatives at which the contents of the Registration Statement and the
Prospectus and related matters were discussed and, although such counsel have
not undertaken to investigate or verify independently, and do not assume any
responsibility for, the accuracy, completeness or fairness of the statements
contained in the Registration Statement or the Prospectus, on the basis of the
foregoing, no facts have come to the attention of such counsel leading such
counsel to believe that the Registration Statement, as of its effective date,
contained any untrue statement of a material fact or omitted to state any
material fact required to be stated therein or necessary to make the statements
therein not misleading or that the Prospectus as of its date or the date of such
opinion, included or includes any untrue statement of a material fact or omitted
or omits to state a material fact necessary in order to make the statements
therein, in the light of the circumstances under which they were made, not
misleading.

     References to the Registration Statement and the Prospectus in this
paragraph (b) shall include any amendment or supplement thereto at the date of
such opinion.

     (c) The Representatives shall have received an opinion, dated the Firm
Closing Date, of Stroock & Stroock & Lavan LLP, counsel for the Underwriters,
with respect to the issuance and sale of the Firm Securities, the Registration
Statement and the Prospectus and such other related matters as the
Representatives may reasonably require, and the Company shall have furnished to
such counsel such documents as they may reasonably request for the purpose of
enabling them to pass upon such matters.

     (d) The Representatives shall have received an opinion, dated the Firm
Closing Date, from Michael, Best & Friedrich, the Company's intellectual
property counsel, in form and

                                      -18-
<PAGE>

substance satisfactory to the Representatives addressing matters relating to the
intellectual property disclosure contained in the Prospectus under the headings
"Risk Factors-Risks Related to Intellectual Property" and "Business-Intellectual
Property" as well as certain matters relating to the Company's proprietary
rights generally.

     (e) The Representatives shall have received from KPMG Peat Marwick a letter
or letters dated, respectively, the date hereof and the Firm Closing Date, in
form and substance satisfactory to the Representatives, to the effect that:

          (i) they are independent accountants with respect to the Company and
     its consolidated subsidiaries within the meaning of the Act, the Exchange
     Act and the applicable rules and regulations thereunder;

          (ii) in their opinion, the audited consolidated financial statements
     examined by them and included in the Registration Statement and the
     Prospectus comply in form in all material respects with the applicable
     accounting requirements of the Act and the related published rules and
     regulations;

          (iii) on the basis of a reading of the last available interim
     unaudited consolidated condensed financial statements of the Company and
     its consolidated subsidiaries which they prepared (the quarter ended
     December 31, 1999), carrying out certain specified procedures (which do not
     constitute an examination made in accordance with generally accepted
     auditing standards) that would not necessarily reveal matters of
     significance with respect to the comments set forth in this paragraph
     (iii), a reading of the minute books of the shareholders, the board of
     directors and any committees thereof of the Company and each of its
     consolidated subsidiaries, and inquiries of certain officials of the
     Company and its consolidated subsidiaries who have responsibility for
     financial and accounting matters, nothing came to their attention that
     caused them to believe that:

               (A) the unaudited consolidated condensed financial statements of
     the Company and its consolidated subsidiaries included in the Registration
     Statement and the Prospectus do not comply in form in all material respects
     with the applicable accounting requirements of the Act and the related
     published rules and regulations thereunder or are not in conformity with
     generally accepted accounting principles applied on a basis substantially
     consistent with that of the audited consolidated financial statements
     included in the Registration Statement and the Prospectus; and

               (B) at a specific date not more than five business days prior to
     the date of such letter, there were any changes in the capital stock or
     long-term debt of the Company and its consolidated subsidiaries or any
     decreases in net current assets or stockholders' equity of the Company and
     its consolidated subsidiaries, in each case compared with amounts shown on
     the December 31, 1999 consolidated balance sheet included in the
     Registration Statement and the Prospectus, or for the period from January
     1, 2000 to such specified date there were any decreases, as compared with
     the comparable period of the prior year in sales, net revenues, net income
     before income taxes or total or per share

                                      -19-
<PAGE>

     amounts of net income of the Company and its consolidated subsidiaries
     except in all instances for changes, decreases or increases set forth in
     such letter; and

          (iv) they have carried out certain specified procedures, not
     constituting an audit, with respect to certain amounts, percentages and
     financial information that are derived from the general accounting records
     of the Company and its consolidated subsidiaries and included in the
     Registration Statement and Prospectus under the captions "Financial
     Statements" and "Selected Consolidated Financial Data" in the Registration
     Statement, and have compared such amounts, percentages and financial
     information with such records of the Company and its consolidated
     subsidiaries and with information derived from such records and have found
     them to be in agreement, excluding any questions of legal interpretation.

     In the event that the letters referred to above set forth any such changes,
     decreases or increases, it shall be a further condition to the obligations
     of the Underwriters that (A) such letters shall be accompanied by a written
     explanation of the Company as to the significance thereof, unless the
     Representatives deem such explanation unnecessary, and (B) such changes,
     decreases or increases do not, in the sole judgment of the Representatives,
     make it impractical or inadvisable to proceed with the purchase and
     delivery of the Securities as contemplated by the Registration Statement,
     as amended as of the date hereof.

     References to the Registration Statement and the Prospectus in this
     paragraph (e) with respect to either letter referred to above shall include
     any amendment or supplement thereto at the date of such letter.

     (f) The Representatives shall have received from Arthur Andersen LLP a
letter or letters dated, respectively, the date hereof and the Firm Closing
Date, in form and substance satisfactory to the Representatives, to the effect
that:

          (i) they are independent accountants with respect to the Company and
     its consolidated subsidiaries within the meaning of the Act and the
     applicable rules and regulations thereunder;

          (ii) on the basis of a reading of the latest available interim
     unaudited consolidated condensed financial statements of the Company and
     its consolidated subsidiaries, carrying out certain specified procedures
     (which do not constitute an examination made in accordance with generally
     accepted auditing standards) that would not necessarily reveal matters of
     significance with respect to the comments set forth in this paragraph (ii),
     a reading of the minute books of the shareholders, the board of directors
     and any committees thereof of the Company and each of its consolidated
     subsidiaries, and inquiries of certain officials of the Company and its
     consolidated subsidiaries who have responsibility for financial and
     accounting matters, nothing came to their attention that caused them to
     believe that:

               (A) the unaudited consolidated condensed financial statements of
     the Company and its consolidated subsidiaries included in the Registration
     Statement and the

                                      -20-
<PAGE>

     Prospectus do not comply in form in all material respects with the
     applicable accounting requirements of the Act and the related published
     rules and regulations thereunder or are not in conformity with generally
     accepted accounting principles applied on a basis substantially consistent
     with that of the audited consolidated financial statements included in the
     Registration Statement and the Prospectus; and

               (B) at a specific date not more than five business days prior to
     the date of such letter, there were any changes in the capital stock or
     long-term debt of the Company and its consolidated subsidiaries or any
     decreases in net current assets or stockholders' equity of the Company and
     its consolidated subsidiaries, in each case compared with amounts shown on
     the March 31, 2000 (June 30, 2000 if the financial statements as of that
     date for the year then ended are included in the Registration Statement and
     Prospectus) consolidated balance sheet included in the Registration
     Statement and the Prospectus, or for the period from April 1, 2000 to such
     specified date there were any decreases, as compared with the comparable
     period of the prior year in sales, net revenues, net income before income
     taxes or total or per share amounts of net income of the Company and its
     consolidated subsidiaries except in all instances for changes, decreases or
     increases set forth in such letter; and

          (iii) they have carried out certain specified procedures, not
     constituting an audit, with respect to certain amounts, percentages and
     financial information that are derived from the general accounting records
     of the Company and its consolidated subsidiaries and included in the
     Registration Statement and Prospectus under the captions "Financial
     Statements" and "Selected Consolidated Financial Data" in the Registration
     Statement, and have compared such amounts, percentages and financial
     information with such records of the Company and its consolidated
     subsidiaries and with information derived from such records and have found
     them to be in agreement, excluding any questions of legal interpretation.

     In the event that the letters referred to above set forth any such changes,
     decreases or increases, it shall be a further condition to the obligations
     of the Underwriters that (A) such letters shall be accompanied by a written
     explanation of the Company as to the significance thereof, unless the
     Representatives deem such explanation unnecessary, and (B) such changes,
     decreases or increases do not, in the sole judgment of the Representatives,
     make it impractical or inadvisable to proceed with the purchase and
     delivery of the Securities as contemplated by the Registration Statement,
     as amended as of the date hereof.

     References to the Registration Statement and the Prospectus in this
     paragraph (f) with respect to either letter referred to above shall include
     any amendment or supplement thereto at the date of such letter.

     (g) The Representatives shall have received a certificate, dated the Firm
Closing Date, of the Chief Executive Officer and the Chief Financial Officer of
the Company to the effect that:

                                      -21-
<PAGE>

          (i) the representations and warranties of the Company in this
     Agreement are true and correct as if made on and as of the Firm Closing
     Date; the Registration Statement, as amended as of the Firm Closing Date,
     does not include any untrue statement of a material fact or omit to state
     any material fact necessary to make the statements therein not misleading,
     and the Prospectus, as amended or supplemented as of the Firm Closing Date,
     does not include any untrue statement of a material fact or omit to state
     any material fact necessary in order to make the statements therein, in the
     light of the circumstances under which they were made, not misleading; and
     the Company has performed all covenants and agreements and satisfied all
     conditions on its part to be performed or satisfied at or prior to the Firm
     Closing Date;

          (ii) no stop order suspending the effectiveness of the Registration
     Statement or any post-effective amendment thereto and no order directed at
     any document incorporated by reference in the Registration Statement or the
     Prospectus or any amendment or supplement thereto has been issued, and no
     proceedings for that purpose have been instituted or threatened or, to the
     best of the Company's knowledge, are contemplated by the Commission; and

          (iii) subsequent to the respective dates as of which information is
     given in the Registration Statement and the Prospectus, neither the Company
     nor any of its subsidiaries has sustained any material loss or interference
     with their respective businesses or properties from fire, flood, hurricane,
     accident or other calamity, whether or not covered by insurance, or from
     any labor dispute or any legal or governmental proceeding, and there has
     not been any material adverse change, or any development involving a
     prospective material adverse change, in the condition (financial or
     otherwise), management, business prospects, net worth or results of
     operations of the Company or any of its subsidiaries, except in each case
     as described in or contemplated by the Prospectus (exclusive of any
     amendment or supplement thereto).

     (h) The Representatives shall have received from each person who is a
director or executive officer of the Company and from certain of the Company's
stockholders, an agreement to the effect that such person will not, directly or
indirectly, without the prior written consent of Prudential Securities
Incorporated, on behalf of the Underwriters, offer, sell, offer to sell,
contract to sell, pledge, grant any option to purchase or otherwise sell or
dispose (or announce any such offer, sale, offer of sale, contract of sale,
pledge, grant of an option to purchase or other sale or disposition) of any
shares of Common Stock or any securities convertible into, or exchangeable or
exercisable for, shares of Common Stock for a period of 90 days after the date
of this Agreement.

     (i) On or before the Firm Closing Date, the Representatives and counsel for
the Underwriters shall have received such further certificates, documents or
other information as they may have reasonably requested from the Company.

     (j) Prior to the commencement of the offering of the Securities, the
Securities shall have been included for trading on the Nasdaq National Market.

                                      -22-
<PAGE>

     All opinions, certificates, letters and documents delivered pursuant to
this Agreement will comply with the provisions hereof only if they are
reasonably satisfactory in all material respects to the Representatives and
counsel for the Underwriters.  The Company shall furnish to the Representatives
such conformed copies of such opinions, certificates, letters and documents in
such quantities as the Representatives and counsel for the Underwriters shall
reasonably request.

     The respective obligations of the several Underwriters to purchase and pay
for any Option Securities shall be subject, in their discretion, to each of the
foregoing conditions to purchase the Firm Securities, except that all references
to the Firm Securities and the Firm Closing Date shall be deemed to refer to
such Option Securities and the related Option Closing Date, respectively.

     8.  Indemnification and Contribution.

     (a) The Company agrees to indemnify and hold harmless each Underwriter and
each person, if any, who controls any Underwriter within the meaning of Section
15 of the Act or Section 20 of the Exchange Act against any losses, claims,
damages or liabilities, joint or several, to which such Underwriter or such
controlling person may become subject under the Act, the Exchange Act or
otherwise, insofar as such losses, claims, damages or liabilities (or actions in
respect thereof) arise out of or are based upon:

          (i) any untrue statement or alleged untrue statement made by the
     Company in Section 2 of this Agreement;

          (ii) any untrue statement or alleged untrue statement of any material
     fact contained in (A) the Registration Statement or any amendment thereto,
     any Preliminary Prospectus or the Prospectus or any amendment or supplement
     thereto or (B) any application or other document, or any amendment or
     supplement thereto, executed by the Company or based upon written
     information furnished by or on behalf of the Company filed in any
     jurisdiction in order to qualify the Securities under the securities or
     blue sky laws thereof or filed with the Commission or any securities
     association or securities exchange (each an "Application");

          (iii) the omission or alleged omission to state in the Registration
     Statement or any amendment thereto, any Preliminary Prospectus or the
     Prospectus or any amendment or supplement thereto, or any Application a
     material fact required to be stated therein or necessary to make the
     statements therein, not misleading; or

          (iv) any untrue statement or alleged untrue statement of any material
     fact contained in any audio or visual materials prepared by the Company or
     based upon written information furnished by or on behalf of the Company
     including, without limitation, slides, videos, films, and tape recordings
     used in connection with the marketing of the Securities, including, without
     limitation, statements communicated to securities analysts employed by the
     Underwriters;

and will reimburse, as incurred, each Underwriter and each such controlling
person for any legal or other expenses reasonably incurred by such Underwriter
or such controlling person in

                                      -23-
<PAGE>

connection with investigating, defending against or appearing as a third-party
witness in connection with any such loss, claim, damage, liability or action;
provided, however, that the Company will not be liable in any such case to the
extent that any such loss, claim, damage or liability arises out of or is based
upon any untrue statement or alleged untrue statement or omission or alleged
omission made in such registration statement or any amendment thereto, any
Preliminary Prospectus, the Prospectus or any amendment or supplement thereto,
or any Application in reliance upon and in conformity with written information
furnished to the Company by such Underwriter through the Representatives
specifically for use therein; and provided, further, that the Company will not
be liable to any Underwriter or any person controlling such Underwriter with
respect to any such untrue statement or omission made in any Preliminary
Prospectus that is corrected in the Prospectus (or any amendment or supplement
thereto) if the person asserting any such loss, claim, damage or liability
purchased Securities from such Underwriter but was not sent or given a copy of
the Prospectus (as amended or supplemented), other than the documents
incorporated by reference therein, at or prior to the written confirmation of
the sale of such Securities to such person in any case where such delivery of
the Prospectus (as amended or supplemented) is required by the Act, unless such
failure to deliver the Prospectus (as amended or supplemented) was a result of
noncompliance by the Company with Sections 5(a), (d) and (e) of this Agreement.
This indemnity agreement will be in addition to any liability which the Company
may otherwise have. The Company will not, without the prior written consent of
the Underwriter or Underwriters purchasing, in the aggregate, more than fifty
percent (50%) of the Securities, settle or compromise or consent to the entry of
any judgment in any pending or threatened claim, action, suit or proceeding in
respect of which indemnification may be sought hereunder (whether or not any
such Underwriter or any person who controls any such Underwriter within the
meaning of Section 15 of the Act or Section 20 of the Exchange Act is a party to
such claim, action, suit or proceeding), unless such settlement, compromise or
consent includes an unconditional release of all of the Underwriters and such
controlling persons from all liability arising out of such claim, action, suit
or proceeding.

     (b) Each Underwriter, severally and not jointly, will indemnify and hold
harmless the Company, each of its directors, each of its officers who signed the
Registration Statement and each person, if any, who controls the Company within
the meaning of Section 15 of the Act or Section 20 of the Exchange Act against
any losses, claims, damages or liabilities to which the Company or any such
director, officer or controlling person may become subject under the Act, the
Exchange Act or otherwise, insofar as such losses, claims, damages or
liabilities (or actions in respect thereof) arise out of or are based upon (i)
any untrue statement or alleged untrue statement of any material fact contained
in the Registration Statement or any amendment thereto, any Preliminary
Prospectus or the Prospectus or any amendment or supplement thereto, or any
Application or (ii) the omission or the alleged omission to state therein a
material fact required to be stated in the Registration Statement or any
amendment thereto, any Preliminary Prospectus or the Prospectus or any amendment
or supplement thereto, or any Application or necessary to make the statements
therein, not misleading, in each case to the extent, but only to the extent,
that such untrue statement or alleged untrue statement or omission or alleged
omission was made in reliance upon and in conformity with written information
furnished to the Company by such Underwriter through the Representatives
specifically for use therein; and, subject to the limitation set forth
immediately preceding this clause, will reimburse, as incurred, any legal or

                                      -24-
<PAGE>

other expenses reasonably incurred by the Company or any such director, officer
or controlling person in connection with investigating or defending any such
loss, claim, damage, liability or any action in respect thereof.  This indemnity
agreement will be in addition to any liability which such Underwriter may
otherwise have.

     (c) Promptly after receipt by an indemnified party under this Section 8 of
notice of the commencement of any action, such indemnified party will, if a
claim in respect thereof is to be made against the indemnifying party under this
Section 8, notify the indemnifying party of the commencement thereof; but the
omission so to notify the indemnifying party will not relieve it from any
liability which it may have to any indemnified party otherwise than under this
Section 8.  In case any such action is brought against any indemnified party,
and it notifies the indemnifying party of the commencement thereof, the
indemnifying party will be entitled to participate therein and, to the extent
that it may wish, jointly with any other indemnifying party similarly notified,
to assume the defense thereof, with counsel satisfactory to such indemnified
party; provided, however, that if the defendants in any such action include both
the indemnified party and the indemnifying party and the indemnified party shall
have reasonably concluded that there may be one or more legal defenses available
to it and/or other indemnified parties which are different from or additional to
those available to the indemnifying party, the indemnifying party shall not have
the right to direct the defense of such action on behalf of such indemnified
party or parties and such indemnified party or parties shall have the right to
select separate counsel to defend such action on behalf of such indemnified
party or parties.  After notice from the indemnifying party to such indemnified
party of its election so to assume the defense thereof and approval by such
indemnified party of counsel appointed to defend such action, the indemnifying
party will not be liable to such indemnified party under this Section 8 for any
legal or other expenses, other than reasonable costs of investigation,
subsequently incurred by such indemnified party in connection with the defense
thereof, unless (i) the indemnified party shall have employed separate counsel
in accordance with the proviso to the next preceding sentence (it being
understood, however, that in connection with such action the indemnifying party
shall not be liable for the expenses of more than one separate counsel (in
addition to local counsel) in any one action or separate but substantially
similar actions in the same jurisdiction arising out of the same general
allegations or circumstances, designated by the Representatives in the case of
paragraph (a) of this Section 8, representing the indemnified parties under such
paragraph (a) who are parties to such action or actions) or (ii) the
indemnifying party does not promptly retain counsel satisfactory to the
indemnified party or (iii) the indemnifying party has authorized the employment
of counsel for the indemnified party at the expense of the indemnifying party.
After such notice from the indemnifying party to such indemnified party, the
indemnifying party will not be liable for the costs and expenses of any
settlement of such action effected by such indemnified party without the consent
of the indemnifying party.

     (d) In circumstances in which the indemnity agreement provided for in the
preceding paragraphs of this Section 8 is unavailable or insufficient, for any
reason, to hold harmless an indemnified party in respect of any losses, claims,
damages or liabilities (or actions in respect thereof), each indemnifying party,
in order to provide for just and equitable contribution, shall contribute to the
amount paid or payable by such indemnified party as a result of such losses,
claims, damages or liabilities (or actions in respect thereof) in such
proportion as is appropriate to reflect (i) the relative benefits received by
the indemnifying party or parties on the one hand

                                      -25-
<PAGE>

and the indemnified party on the other from the offering of the Securities or
(ii) if the allocation provided by the foregoing clause (i) is not permitted by
applicable law, not only such relative benefits but also the relative fault of
the indemnifying party or parties on the one hand and the indemnified party on
the other in connection with the statements or omissions or alleged statements
or omissions that resulted in such losses, claims, damages or liabilities (or
actions in respect thereof), as well as any other relevant equitable
considerations. The relative benefits received by the Company on the one hand
and the Underwriters on the other shall be deemed to be in the same proportion
as the total proceeds from the offering (before deducting expenses) received by
the Company to the total underwriting discounts and commissions received by the
Underwriters. The relative fault of the parties shall be determined by reference
to, among other things, whether the untrue or alleged untrue statement of a
material fact or the omission or alleged omission to state a material fact
relates to information supplied by the Company or the Underwriters, the parties'
relative intents, knowledge, access to information and opportunity to correct or
prevent such statement or omission, and any other equitable considerations
appropriate in the circumstances. The Company and the Underwriters agree that it
would not be equitable if the amount of such contribution were determined by pro
rata or per capita allocation (even if the Underwriters were treated as one
entity for such purpose) or by any other method of allocation that does not take
into account the equitable considerations referred to above in this paragraph
(d). Notwithstanding any other provision of this paragraph (d), no Underwriter
shall be obligated to make contributions hereunder that in the aggregate exceed
the total public offering price of the Securities purchased by such Underwriter
under this Agreement, less the aggregate amount of any damages that such
Underwriter has otherwise been required to pay in respect of the same or any
substantially similar claim, and no person guilty of fraudulent
misrepresentation (within the meaning of Section 11(f) of the Act) shall be
entitled to contribution from any person who was not guilty of such fraudulent
misrepresentation. The Underwriters' obligations to contribute hereunder are
several in proportion to their respective underwriting obligations and not
joint, and contributions among Underwriters shall be governed by the provisions
of the Prudential Securities Incorporated Master Agreement Among Underwriters.
For purposes of this paragraph (d), each person, if any, who controls an
Underwriter within the meaning of Section 15 of the Act or Section 20 of the
Exchange Act shall have the same rights to contribution as such Underwriter, and
each director of the Company, each officer of the Company who signed the
Registration Statement and each person, if any, who controls the Company within
the meaning of Section 15 of the Act or Section 20 of the Exchange Act, shall
have the same rights to contribution as the Company.

     9.  Default of Underwriters.  If one or more Underwriters default in their
obligations to purchase Firm Securities or Option Securities hereunder and the
aggregate number of such Securities that such defaulting Underwriter or
Underwriters agreed but failed to purchase is ten percent or less of the
aggregate number of Firm Securities or Option Securities to be purchased by all
of the Underwriters at such time hereunder, the other Underwriters may make
arrangements satisfactory to the Representatives for the purchase of such
Securities by other persons (who may include one or more of the non-defaulting
Underwriters, including the Representatives), but if no such arrangements are
made by the Firm Closing Date or the related Option Closing Date, as the case
may be, the other Underwriters shall be obligated severally in proportion to
their respective commitments hereunder to purchase the Firm Securities or Option
Securities that such defaulting Underwriter or Underwriters agreed but failed to
purchase.  If one

                                      -26-
<PAGE>

or more Underwriters so default with respect to an aggregate number of
Securities that is more than ten percent of the aggregate number of Firm
Securities or Option Securities, as the case may be, to be purchased by all of
the Underwriters at such time hereunder, and if arrangements satisfactory to the
Representatives are not made within 36 hours after such default for the purchase
by other persons (who may include one or more of the non-defaulting
Underwriters, including the Representatives) of the Securities with respect to
which such default occurs, this Agreement will terminate without liability on
the part of any non-defaulting Underwriter or the Company other than as provided
in Section 10 hereof. In the event of any default by one or more Underwriters as
described in this Section 9, the Representatives shall have the right to
postpone the Firm Closing Date or the Option Closing Date, as the case may be,
established as provided in Section 3 hereof for not more than seven business
days in order that any necessary changes may be made in the arrangements or
documents for the purchase and delivery of the Firm Securities or Option
Securities, as the case may be. As used in this Agreement, the term
"Underwriter" includes any person substituted for an Underwriter under this
Section 9. Nothing herein shall relieve any defaulting Underwriter from
liability for its default.

     10.  Survival.  The respective representations, warranties, agreements,
covenants, indemnities and other statements of the Company, its officers and the
several Underwriters set forth in this Agreement or made by or on behalf of
them, respectively, pursuant to this Agreement shall remain in full force and
effect, regardless of (i) any investigation made by or on behalf of the Company,
any of its officers or directors, any Underwriter or any controlling person
referred to in Section 8 hereof and (ii) delivery of and payment for the
Securities.  The respective agreements, covenants, indemnities and other
statements set forth in Sections 6 and 8 hereof shall remain in full force and
effect, regardless of any termination or cancellation of this Agreement.

     11.  Termination.  (a) This Agreement may be terminated with respect to the
Firm Securities or any Option Securities in the sole discretion of the
Representatives by notice to the Company given prior to the Firm Closing Date or
the related Option Closing Date, respectively, in the event that the Company
shall have failed, refused or been unable to perform all obligations and satisfy
all conditions on its part to be performed or satisfied hereunder at or prior
thereto or, if at or prior to the Firm Closing Date or such Option Closing Date,
respectively,

          (i) the Company or any of its subsidiaries shall have, in the sole
     judgment of the Representatives, sustained any material loss or
     interference with their respective businesses or properties from fire,
     flood, hurricane, accident or other calamity, whether or not covered by
     insurance, or from any labor dispute or any legal or governmental
     proceeding or there shall have been any material adverse change, or any
     development involving a prospective material adverse change (including
     without limitation a change in management or control of the Company), in
     the condition (financial or otherwise), business prospects, net worth or
     results of operations of the Company and its subsidiaries except in each
     case as described in or contemplated by the Prospectus (exclusive of any
     amendment or supplement thereto);

          (ii) trading in the Common Stock shall have been suspended by the
     Commission or the Nasdaq National Market, or trading in securities
     generally on the New

                                      -27-
<PAGE>

     York Stock Exchange or the Nasdaq National Market shall have been suspended
     or minimum or maximum prices shall have been established on either such
     exchange;

          (iii) a banking moratorium shall have been declared by New York or
     United States authorities; or

          (iv) there shall have been (A) an outbreak or escalation of
     hostilities between the United States and any foreign power, (B) an
     outbreak or escalation of any other insurrection or armed conflict
     involving the United States or (C) any other calamity or crisis or material
     adverse change in general economic, political or financial conditions
     having an effect on the U.S. financial markets that, in the sole judgment
     of the Representatives, makes it impractical or inadvisable to proceed with
     the public offering or the delivery of the Securities as contemplated by
     the Registration Statement, as amended as of the date hereof.

     (b) Termination of this Agreement pursuant to this Section 11 shall be
without liability of any party to any other party except as provided in Section
10 hereof.

     12.  Information Supplied by Underwriters.  The statements set forth in the
last paragraph on the front cover page and under the heading "Underwriting" in
any Preliminary Prospectus or the Prospectus (to the extent such statements
relate to the Underwriters) constitute the only information furnished by any
Underwriter through the Representatives to the Company for the purposes of
Sections 2(b) and 8 hereof.  The Underwriters confirm that such statements (to
such extent) are correct.

     13.  Notices.  All communications hereunder shall be in writing and, if
sent to any of the Underwriters, shall be delivered or sent by mail, telex or
facsimile transmission and confirmed in writing to Prudential Securities
Incorporated, One New York Plaza, New York, New York 10292, Attention: Equity
Transactions Group; and if sent to the Company, shall be delivered or sent by
mail, telex or facsimile transmission and confirmed in writing to the Company at
Bone Care International, Inc., One Science Court, Madison, Wisconsin 53711,
Attention: Charles W. Bishop, Ph. D.

     14.  Successors.  This Agreement shall inure to the benefit of and shall be
binding upon the several Underwriters, the Company and their respective
successors and legal representatives, and nothing expressed or mentioned in this
Agreement is intended or shall be construed to give any other person any legal
or equitable right, remedy or claim under or in respect of this Agreement, or
any provisions herein contained, this Agreement and all conditions and
provisions hereof being intended to be and being for the sole and exclusive
benefit of such persons and for the benefit of no other person except that (i)
the indemnities of the Company contained in Section 8 of this Agreement shall
also be for the benefit of any person or persons who control any Underwriter
within the meaning of Section 15 of the Act or Section 20 of the Exchange Act
and (ii) the indemnities of the Underwriters contained in Section 8 of this
Agreement shall also be for the benefit of the directors of the Company, the
officers of the Company who have signed the Registration Statement and any
person or persons who control the Company within the meaning of Section 15 of
the Act or Section 20 of the Exchange Act. No

                                      -28-
<PAGE>

purchaser of Securities from any Underwriter shall be deemed a successor because
of such purchase.

     15.  Applicable Law.  The validity and interpretation of this Agreement,
and the terms and conditions set forth herein, shall be governed by and
construed in accordance with the laws of the State of New York, without giving
effect to any provisions relating to conflicts of laws.

     16.  Consent to Jurisdiction and Service of Process.  All judicial
proceedings arising out of or relating to this Agreement may be brought in any
state or federal court of competent jurisdiction in the State of New York.

     17.  Counterparts.  This Agreement may be executed in two or more
counterparts, each of which shall be deemed an original, but all of which
together shall constitute one and the same instrument.

     If the foregoing correctly sets forth our understanding, please indicate
your acceptance thereof in the space provided below for that purpose, whereupon
this letter shall constitute an agreement binding the Company and each of the
several Underwriters.

                                      -29-
<PAGE>

                                Very truly yours,

                                BONE CARE INTERNATIONAL, INC.



                                By:__________________________________________
                                  Name:  Charles W. Bishop, Ph. D.
                                  Title: President, Chief Executive Officer
                                         and Director


The foregoing Agreement is hereby
confirmed and accepted as of the
date first above written.

PRUDENTIAL SECURITIES INCORPORATED
U.S. BANCORP PIPER JAFFRAY INCORPORATED

By: PRUDENTIAL SECURITIES INCORPORATED


By:_______________________________
   Name:  Jean Claude Canfin
   Title: Managing Director

For itself and on behalf of the Representatives.

                                      -30-
<PAGE>

                                   SCHEDULE I

                                  UNDERWRITERS


<TABLE>
<CAPTION>

                                                  Number of
                                                Securities to
Underwriter                                     be Purchased
-----------                                     -------------
<S>                                             <C>
Prudential Securities Incorporated
U.S. Bancorp Piper Jaffray Incorporated















                  Total......................     3,000,000
                                               ---------------
</TABLE>

                                      -31-


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