PHYSIOMETRIX INC
POS AM, 1996-09-13
ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS
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<PAGE>

As filed with the Securities and Exchange Commission on        , 1996
                                                       Registration No. 333-2138
- --------------------------------------------------------------------------------

                          SECURITIES AND EXCHANGE COMMISSION
                                WASHINGTON, D.C. 20549

                                   ---------------

                            POST-EFFECTIVE AMENDMENT NO.1
                                          TO
                                       FORM S-1
                                REGISTRATION STATEMENT
                                        UNDER
                              THE SECURITIES ACT OF 1933

                                   ---------------

                                  PHYSIOMETRIX, INC.
                (Exact name of Registrant as specified in its charter)

                                   ---------------

   DELAWARE                        3845                       77-0238187
(State or other         (Primary Standard Industrial       (I.R.S. Employer
jurisdiction of          Classification Code Number)     Identification Number)
incorporation or
organization)

                                 FIVE BILLERICA PARK
                                 101 BILLERICA AVENUE
                              NORTH BILLERICA, MA 01862
                                    (508)670-2422
    (Address, including zip code, and telephone number, including area code,
                     of Registrant's principal executive offices)

                                   ---------------

                                   JOHN A. WILLIAMS
                        PRESIDENT AND CHIEF EXECUTIVE OFFICER
                                  PHYSIOMETRIX, INC.
                                 FIVE BILLERICA PARK
                                 101 BILLERICA AVENUE
                              NORTH BILLERICA, MA 01862
                                    (508)670-2422
         (Name, address, including zip code, and telephone number, including
                           area code, of agent for service)

                                   ---------------

                                      COPIES TO:

       J. CASEY MCGLYNN, ESQ.                     MARK A. KLEIN, ESQ.
    CHRISTOPHER D. MITCHELL, ESQ.                 MARK J. KELSON, ESQ.
WILSON SONSINI GOODRICH & ROSATI P.C.          FRESHMAN, MARANTZ, ORLANSKI,
     PROFESSIONAL CORPORATION                        COOPER & KLEIN
        650 PAGE MILL ROAD                      EIGHTH FLOOR, EAST TOWER
       PALO ALTO, CA 94304                         9100 WILSHIRE BLVD.
          (415)493-9300                     BEVERLY HILLS, CALIFORNIA 90212-3480
                                                      (310)273-1870

                                   ---------------

- --------------------------------------------------------------------------------

<PAGE>

                                  PHYSIOMETRIX, INC.

    This Registration Statement, as amended to the date of its effectiveness
(April 30, 1996), registered 2,300,000 shares of the Common Stock of
Physiometrix, Inc. (the "Registrant").  Of this amount, the Registrant sold an
aggregate of 2,000,000 shares to the Underwriters.  The offering has now been
terminated.  Accordingly, the Registrant hereby deregisters 300,000 shares of
the Common Stock originally covered by the Registration Statement.


                                         -2-

<PAGE>

                                      SIGNATURES

    Pursuant to the requirements of the Securities Act of 1933, the Registrant
has duly caused this Post-Effective Amendment No. 1 to the Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of North Billerica, State of Massachusetts on this 30th
day of June, 1996.

                                       PHYSIOMETRIX, INC.


                                       By: /s/ John A. Williams
                                          ------------------------------------
                                          John A. Williams
                                          President and Chief Executive Officer

    Pursuant to the requirements of the Securities Act of 1933, the Amendment
to the Registration Statement has been signed by the following persons in the
capacities and on the dates indicated:

    NAME AND SIGNATURE                   TITLE                      DATE
- ---------------------------   ----------------------------------  -------------

/s/ John A. Williams          President, Chief Executive Officer  June 30, 1996
- ---------------------------   and Director
  John A. Williams*           (Principal Executive Officer)

/s/ Michael J. Tubridy        Vice President of Finance and       June 30, 1996
- ---------------------------   Administration and Chief Financial
  Michael J. Tubridy          Officer
                              (Principal Financial and Accounting
                              Officer)

/s/ Thomas Baruch             Chairman of the Board of Directors  June 30, 1996
- ---------------------------
  Thomas Baruch

/s/ Thomas J. Fogarty, M.D.   Director                            June 30, 1996
- ---------------------------
  Thomas J. Fogarty, M.D.

/s/ Mir A. Imran              Director                            June 30, 1996
- ---------------------------
  Mir A. Imran

/s/ Thomas J. Toy             Director                            June 30, 1996
- ---------------------------
  Thomas J. Toy

/s/ Harold C. Hohback         Director                            June 30, 1996
- ---------------------------
  Harold C. Hohback

/s/ Annette Campbell-White    Director                            June 30, 1996
- ---------------------------
  Annette Campbell-White

*By:  John A. Williams, Attorney-in-Fact


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