MICROCIDE PHARMACEUTICALS INC
10-Q, 1998-08-14
PHARMACEUTICAL PREPARATIONS
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549


                                    FORM 10-Q



(X)      QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
         EXCHANGE ACT OF 1934 FOR THE QUARTERLY PERIOD ENDED JUNE 30, 1998


OR

(  )     TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
         EXCHANGE ACT OF 1934


                         Commission file number: 0-28006


                         MICROCIDE PHARMACEUTICALS, INC.
             (Exact name of registrant as specified in its charter)


           Delaware                                             94-3186021
(State or other jurisdiction of                             (I.R.S. Employer
 incorporation of organization)                           Identification Number)

850 Maude Avenue, Mountain View, California                     94043
 (Address of principal executive offices)                       (ZIP Code)


Registrant's telephone number, including area code:             650-428-1550


Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12 months (or for such shorter period  that  the  registrant  was
required  to file  such  reports),  and  (2) has  been  subject  to such  filing
requirements for the past 90 days.

                                 Yes X      No
                                    ---    ---

Number of shares of Common Stock, no par value, outstanding as of July 31, 1998:
10,971,930.


<PAGE>


                         MICROCIDE PHARMACEUTICALS, INC.

                               INDEX FOR FORM 10-Q

                                  JUNE 30, 1998


                                                                           PAGE
                                                                          NUMBER
PART I    FINANCIAL INFORMATION

Item 1.   Financial Statements and Notes

          Condensed Balance Sheets as of June 30, 1998
          and December 31, 1997                                                3

          Condensed Statements of Operations for the three
          and six months ended June 30, 1998 and June 30, 1997                 4

          Condensed Statements of Cash Flows for the six
          months ended June 30, 1998 and June 30, 1997                         5

          Notes to Condensed Financial Statements                              6

Item 2.   Management's Discussion and Analysis of Financial
          Condition and Results of Operations                                  8


PART II   OTHER INFORMATION                                                   11

Item 1.   Legal Proceedings

Item 2.   Changes in Securities

Item 3.   Defaults in Senior Securities

Item 4.   Submission of Matters to a Vote of Security Holders

Item 5.   Other Information

Item 6.   Exhibits and Reports on Form 8-K


SIGNATURES                                                                   13

                                       -2-

<PAGE>


                         MICROCIDE PHARMACEUTICALS, INC.

                            CONDENSED BALANCE SHEETS
                                 (In thousands)


                                                          June 30,  December 31,
                                                             1998        1997
                                                           --------    --------
                                                         (Unaudited)
ASSETS
     Current assets:
          Cash and cash equivalents                        $  2,890    $ 11,763
          Short-term investments                             31,024      28,624
          Prepaid expenses and other current assets           1,925       1,284
                                                           --------    --------
     Total current assets                                    35,839      41,671
                                                           --------    --------

          Property and equipment, net                         9,780       9,540
          Other assets                                          885         571
                                                           --------    --------

Total assets                                               $ 46,504    $ 51,782
                                                           ========    ========


LIABILITIES AND STOCKHOLDERS' EQUITY
     Current liabilities:
          Accounts payable                                 $    990    $  1,313
          Construction payable                                  344         347
          Accrued compensation                                  779         746
          Current portion of capital lease obligations          377         612
          Deferred revenue                                      875         786
          Other accrued liabilities                             675         632
                                                           --------    --------
     Total current liabilities                                4,040       4,436
                                                           --------    --------

     Long-term portion of capital lease obligations              82         224
     Accrued rent                                               164         226


Stockholders' equity:
     Common stock                                            66,792      66,930
     Deferred compensation                                     (725)     (1,251)
     Net unrealized loss on marketable securities               (58)        (44)
     Accumulated deficit                                    (23,791)    (18,739)
                                                           --------    --------
Total stockholders' equity                                   42,218      46,896
                                                           --------    --------

Total liabilities & stockholders' equity                   $ 46,504    $ 51,782
                                                           ========    ========


NOTE:  The balance  sheet at December 31, 1997 has been derived from the audited
financial  statements  at that date but does not include all of the  information
and footnotes required by generally accepted accounting  principles for complete
financial statements.

                  See Notes to Condensed Financial Statements.

                                      -3-

<PAGE>


<TABLE>
                                                   Microcide Pharmaceuticals, Inc.

                                                 Condensed Statements of Operations
                                              (In thousands, except per share amounts)
                                                             (Unaudited)

<CAPTION>
                                                                            Three Months Ended               Six Months Ended
                                                                                 June 30,                         June 30,
                                                                        -------------------------         -------------------------
                                                                          1998             1997             1998             1997
                                                                        --------         --------         --------         --------
<S>                                                                     <C>              <C>              <C>              <C>     
Revenues
     License and milestone fees                                         $   --           $   --           $   --           $  1,000
     Research revenue                                                      2,800            2,994            5,835            6,101
                                                                        --------         --------         --------         --------

Total revenues                                                             2,800            2,994            5,835            7,101

Operating expenses
     Research and development                                              4,815            4,336            9,876            8,437
     General and administrative                                              953            1,099            2,011            2,121
                                                                        --------         --------         --------         --------

Total operating expenses                                                   5,768            5,435           11,887           10,558
                                                                        --------         --------         --------         --------


Loss from operations                                                      (2,968)          (2,441)          (6,052)          (3,457)

Interest income                                                              504              650            1,030            1,338
Interest expense                                                             (12)             (40)             (30)             (93)
                                                                        --------         --------         --------         --------
Net loss                                                                $ (2,476)        $ (1,831)        $ (5,052)        $ (2,212)
                                                                        ========         ========         ========         ========

Net loss per share                                                      $  (0.23)        $  (0.17)        $  (0.46)        $  (0.21)
                                                                        ========         ========         ========         ========


Shares used in calculation of net loss per share                          10,957           10,778           10,941           10,797

<FN>
                                            See Notes to Condensed Financial Statements.
</FN>
</TABLE>

                                                                -4-

<PAGE>


<TABLE>
                                                   Microcide Pharmaceuticals, Inc.

                                                 CONDENSED STATEMENTS OF CASH FLOWS
                                          Increase (decrease) in cash and cash equivalents


<CAPTION>
                                                                                                            Six Months Ended
                                                                                                                 June 30
                                                                                                      -----------------------------
                                                                                                        1998                 1997
                                                                                                      --------             --------
<S>                                                                                                   <C>                  <C>      
Cash flows used in operating activities:
     Net loss                                                                                         $ (5,052)            $ (2,212)
     Adjustments to reconcile net loss to net cash provided by
     (used in) operating activities:
          Depreciation and amortization                                                                  1,466                1,258
          Amortization of deferred compensation                                                            264                  295
          Accrued rent                                                                                     (62)                  32
          Net unrealized gain (loss) on securities                                                         (14)                  25
     Changes in assets and liabilities:
          Prepaid expenses and other current assets                                                       (641)                (235)
          Other assets                                                                                    (314)                   6
          Accounts payable                                                                                (326)              (1,355)
          Accrued compensation and other accrued liabilities                                                76                  389
          Deferred revenue                                                                                  89                  125
                                                                                                      --------             --------

Net cash used in operating activities                                                                   (4,514)              (1,672)
                                                                                                      --------             --------

Cash flows used in investing activities:
     Purchase of short-term investments                                                                (26,410)             (62,015)
     Maturities of short-term investments                                                               24,010               61,290
     Capital expenditures                                                                               (1,708)              (1,308)
                                                                                                      --------             --------

Net cash provided by (used in) investing activities                                                     (4,108)              (2,033)
                                                                                                      --------             --------

Cash flows financing activities:
     Principal payments on capital lease obligations                                                      (377)                (582)
     Repayment of shareholder note                                                                           0                   35
     Net proceeds from issuance of common stock                                                            126                  126
                                                                                                      --------             --------

Net cash used in financing activities                                                                     (251)                (421)
                                                                                                      --------             --------

Net decrease in cash and cash equivalents                                                               (8,873)              (4,126)
Cash and cash equivalents at beginning of period                                                        11,763                8,317
                                                                                                      --------             --------

Cash and cash equivalents at end of period                                                            $  2,890             $  4,191
                                                                                                      ========             ========

Supplemental disclosure of cash flow information:
     Income taxes paid                                                                                $      2             $     21
                                                                                                      ========             ========
     Interest paid                                                                                    $     30             $     81
                                                                                                      ========             ========

<FN>
                                            See Notes to Condensed Financial Statements.
</FN>
</TABLE>

                                                                -5-

<PAGE>

                         MICROCIDE PHARMACEUTICALS, INC.

                     NOTES TO CONDENSED FINANCIAL STATEMENTS

                                  June 30, 1998
                                   (Unaudited)


1.  Summary of Significant Accounting Policies
     Organization and Basis of Presentation

         Microcide Pharmaceuticals,  Inc. (the "Company") is a biopharmaceutical
company  whose  mission  is  to  discover,   develop  and  commercialize   novel
antimicrobials for the improved treatment of serious bacterial, fungal and viral
infections. The Company's discovery and development programs address the growing
problem of bacterial drug  resistance  and the need for improved  antifungal and
antiviral agents through two principal themes: (i) Targeted  Antibiotics,  which
focuses on developing novel antibiotics and antibiotic  potentiators to directly
address existing  bacterial  resistance  problems,  and (ii) Targeted  Genomics,
which utilizes  bacterial,  fungal and viral genetics to discover new classes of
antimicrobials and other novel treatments for infectious diseases.

         The accompanying  unaudited  condensed  financial  statements have been
prepared in accordance with generally accepted accounting principles for interim
financial  information and with the  instructions to Form 10-Q and Rule 10-01 of
Regulation  S-X.  Accordingly,  they do not include all of the  information  and
footnotes  required by generally  accepted  accounting  principles  for complete
financial statements. In the opinion of management,  all adjustments (consisting
of normal recurring accruals)  considered necessary for a fair presentation have
been included.  The results of operations  for the interim  periods shown herein
are not necessarily indicative of operating results for the entire year.

         This unaudited  financial  data should be read in conjunction  with the
financial  statements and footnotes  contained in the Company's annual report on
Form 10-K for the year ended December 31, 1997.

2.  Investments

         Investment securities are classified as  available-for-sale  (estimated
fair value) and consist of the following investments (in thousands):

                                                     June 30,       December 31,
                                                       1998             1997
                                                     -------           -------
Cash equivalents and short-term investments:                        
         Money market funds                          $ 4,588           $ 2,133
         Corporate debt securities                    26,436            37,417
                                                     -------           -------
                                                     $31,024           $39,550
                                                     =======           =======
                                                                    
                                       -6-
<PAGE>




3.  Per Share Information

         Effective December 31, 1997, the Company adopted statement of Financial
Accounting  Standards  No. 128  "Earnings  per  Share"  ("SFAS  128").  SFAS 128
requires  the  presentation  of basic  earnings  (loss)  per share  and  diluted
earnings  (loss) per share,  if more  dilutive,  for all periods  presented.  In
accordance  with SFAS 128,  basic net loss per share has been computed using the
weighted-average number of shares of Common Stock outstanding during the period.
Diluted net loss per share has not been presented;  given the Company's net loss
position, the result would be anti-dilutive.

4. Changes in Accounting Standards

         As of January 31,  1998,  the Company  adopted  Statement  of Financial
Accounting Standards No. 130 "Reporting Comprehensive Income" ("SFAS 130"). SFAS
130 established new rules for the reporting and display of comprehensive  income
and its components; however, the adoption of this Statement has no impact on the
Company's  net loss or  stockholders'  equity.  SFAS 130  requires,  among other
things, unrealized gains or losses on the Company's securities to be included in
comprehensive  income or loss.  During  the six months  ended June 30,  1998 and
1997, the Company's  comprehensive  loss amounted to $5,066,000 and  $2,187,000,
respectively.


                                      -7-
<PAGE>




                         MICROCIDE PHARMACEUTICALS, INC.

         Management's Discussion and Analysis of Financial Condition and
                              Results of Operations

Overview

         As  part  of  the  Company's  strategy  to  enhance  its  research  and
development  capabilities  and to  fund,  in  part,  its  capital  requirements,
Microcide   has  entered  into   collaborative   agreements   with  three  major
pharmaceutical  companies.  The  Company has  received  license  fees,  research
support  payments and milestone  payments  pursuant to these  agreements and can
potentially receive additional research support payments,  additional  milestone
payments and royalty  payments.  License  payments are  typically  nonrefundable
up-front payments for licenses to develop,  manufacture and market products,  if
any,  that are  developed  as a result of the  collaboration.  Research  support
payments are  typically  contractually  obligated  payments to fund research and
development over the term of the collaboration.  Milestone payments are payments
contingent  upon the achievement of specified  milestones,  such as selection of
candidates for drug development,  the commencement of clinical trials or receipt
of regulatory approvals.  If drugs are successfully developed and commercialized
as a result of the  collaborative  agreements,  the Company will receive royalty
payments based upon the net sales of such drugs.

         Through June 30, 1998, the Company had received in the aggregate  $35.0
million in license fees,  milestone payments and research support payments under
the  collaborative  agreements.  Assuming  none  of the  existing  collaborative
agreements is terminated prior to its scheduled expiration,  the Company will be
entitled  to receive up to an  additional  $16.0  million  of  research  support
payments. In addition, in the event that any of the collaborative agreements are
extended  beyond their  current  terms,  the Company will be entitled to receive
additional research support payments.

         In the event that the  Company  achieves  the  specified  research  and
product  development  milestones,  the  Company  will  be  entitled  to  receive
milestone  payments  under its  collaborative  agreements  with the three  major
pharmaceutical  companies  ranging  from  $13.0  million  to $32.5  million  per
product.  No royalty  payments  have yet been  received and the Company does not
expect to receive  royalties based upon the net sales of drugs for a significant
number of years, if ever.

         In May  1998,  the  Company  signed  an  agreement  to  extend  various
facilities  leases for a 60-month  term after their  scheduled  expiration.  The
lease combines other  previous  agreements  signed in relation to its facilities
comprising  71,210 square feet.  The agreement  calls for total minimum  monthly
rental payments ranging from $132,000 to $152,000 beginning on October 1, 2000.

         Quarterly results of operations are subject to significant fluctuations
based  on  the  timing  and  amount  of  certain   revenues   earned  under  the
collaborative  agreements.  The Company expects to incur operating losses in the
future.

         This Form 10-Q contains  forward-looking  statements based upon current
expectations,  including  statements  with  regard to the  potential  receipt of
additional research support payments,  milestone payments and royalties from the
Company's  collaborative partners, and the period of time the Company's existing
capital  resources and future  payments under  collaborative  agreements will be
sufficient  to  satisfy  the  Company's   funding   requirements,   expectations
concerning  the  Company's  


                                      -8-
<PAGE>

future  research and  development  and general and  administrative  expenses and
future  facility  needs.  Such  forward-looking   statements  involve  risk  and
uncertainties,  including  without  limitation,  the  risk  that  the  Company's
collaborations   will  be  terminated,   development   candidates  will  not  be
identified,  development  candidates which are selected will not proceed through
pre-clinical trials or will not prove safe and effective for treatment of humans
in clinical trials, or that the  identification,  selection,  pre-clinical,  and
clinical testing of development  candidates will take substantially longer or be
substantially  more  expensive  than  contemplated  by the Company,  or that the
Company  will not be able to  obtain  on a timely  basis  government  regulatory
clearance  required for clinical  testing,  manufacturing,  and marketing of its
products,  and the other  risks  and  uncertainties  set forth in the  Company's
annual report on Form 10-K for the year ended December 31, 1997.  Actual results
and timing of certain events could differ materially from those indicated in the
forward-looking statements as a result of these or other factors.

Results of Operations

Three Months Ended June 30, 1998 and 1997

Revenues.  Total  revenues for the second  quarter of 1998 were $2.8 million,  a
decrease  of 6% from the $3.0  million  in  revenues  recognized  in the  second
quarter of 1997,  due to a  decrease  in  research  support  revenues.  Research
support  revenue  decreased in the second quarter of 1998 due primarily to lower
revenues  earned  from the  Daiichi  collaborative  agreement  resulting  from a
decrease  in  reimbursable  costs  associated  with the  program.  There were no
license and milestone fees earned for either period.

Research and Development  Expenses.  Research and  development  expenses for the
second  quarter  increased  approximately  11% from $4.3 million in 1997 to $4.8
million in 1998.  The  increases are due  primarily to higher  compensation  and
other  employee-related  expenses  associated  with an increase in  headcount to
support the Company's corporate collaborations and its internal programs, higher
spending for research supplies and materials,  higher costs relating to expanded
research  and  development  facilities,  and  costs  associated  with  providing
research  support  to  Iconix  Pharmaceuticals  related  to the  viral  research
program,  partially offset by lower expenses related to assembling the Company's
molecular diversity  collection.  Research and development expenses are expected
to further increase in the third quarter.

General and Administrative Expenses. General and administrative expenses for the
second quarter  decreased 13% from $1.1 million in 1997 to $1.0 million in 1998.
Decreased  expenses primarily  consisted of lower operational costs,  travel and
entertainment costs, and facilities costs.  General and administrative  expenses
may increase in dollar amounts in the third quarter, but are expected to be at a
lower percentage of total operating expenses.

Interest Income and Expense.  Interest  income for the second quarter  decreased
from  $650,000  in 1997 to  $504,000  in 1998,  primarily  due to a decrease  in
average cash balances.  Interest  expense for the second quarter  decreased from
$40,000 in 1997 to $12,000 in 1998 due to a decrease in capital  lease  balances
outstanding.

Six Months Ended June 30, 1998 and 1997

Revenues.  Total  revenues  for the  first  half of 1998 were  $5.8  million,  a
decrease  of 18% from the $7.1  million in  revenues  for the first half of 1997
primarily due to a decrease in license and



                                      -9-
<PAGE>

milestone  fees.  In addition,  research  support  revenue  decreased  from $6.1
million  in the first  half of 1997 to $5.8  million  in the first  half of 1998
primarily as a result of lower  revenues  earned from the Daiichi  collaborative
agreement  resulting from a decrease in reimbursable  costs  associated with the
program.

Research and Development  Expenses.  Research and  development  expenses for the
first half of 1998 were $9.9 million, an increase of approximately 17% from $8.4
million in the first half of 1997,  primarily due to increased  compensation and
other  employee-related  expenses  associated  with an increase in  headcount to
support the Company's corporate collaborations and its internal programs, higher
spending for research supplies and materials,  higher costs relating to expanded
research  and  development  facilities,  and  costs  associated  with  providing
research  support  to  Iconix  Pharmaceuticals  related  to the  viral  research
program,  partially offset by lower expenses related to assembling the Company's
molecular diversity  collection.  Research and development expenses are expected
to further increase in the second half of 1998.

General and Administrative Expenses. General and administrative expenses for the
first half of 1998 decreased  approximately 5% from $2.1 million in 1997 to $2.0
million in 1998.  Decreased  expenses  primarily  consisted of lower payroll and
related expenses,  lower  operational  costs, and lower travel and entertainment
costs,  partially offset by an increase in outside service  expenses  associated
with  recruiting,  legal and insurance  activities.  General and  administrative
expenses may  increase in dollar  amounts in the second half of 1998 as compared
to the first half of 1998, but are expected to be at a lower percentage of total
operating expenses.

Interest  Income  and  Expense.  Interest  income  for  the  first  half of 1998
decreased from $1.3 million in 1997 to $1.0 million in 1998,  primarily due to a
decrease in average cash balances.  Interest  expense  decreased from $93,000 in
the first half of 1997 to $30,000 in the first half of 1998 due to a decrease in
capital lease balances outstanding.

Liquidity and Capital Resources

         The Company has  financed  its  operations  since  inception  primarily
through  the  sale  of  equity,   through  funds  provided  under  collaborative
agreements,  through other revenues principally consisting of sales of molecular
diversity  samples  and  through  equipment  financing.  As of June 30, 1998 the
Company had received  approximately  $64.5 million in net proceeds from the sale
of equity and  approximately  $36.7  million  from license and  milestone  fees,
research support payments under collaborative  agreements and sales of molecular
diversity samples.

         Cash, cash equivalents and short-term investments at June 30, 1998 were
$33.9  million  compared to $40.4  million at December  31,  1997.  The decrease
during the first half of 1998 was due  primarily to cash used by  operations  of
$4.5  million,  $1.7 million in capital  expenditures  and $251,000  utilized in
financing  activities  which  predominantly  consisted of principal  payments on
capital lease obligations.

         The Company  believes  that its existing  capital  resources,  interest
income and future  payments due under  collaborative  agreements will enable the
Company to maintain current and planned operations at least through 1999.


                                      -10-
<PAGE>


PART II      OTHER INFORMATION

Item 1.      Legal Proceedings

             None.

Item 2.      Changes in Securities

             None.

Item 3.      Defaults in Senior Securities

             None.

Item 4.      Submission of Matters to a Vote of Security Holders

       (a)   The Annual Meeting of  Stockholders  of Microcide  Pharmaceuticals,
             Inc. was held on June 18, 1998.
<TABLE>

       (b)   The following  Class II Directors  were elected to serve for a term
             of three years to expire at the  Company's  2001 Annual  Meeting of
             Stockholders:
<CAPTION>

             Name                                    Position                            Term Expires
             ----------------------------------      ---------------------------------   ------------
<S>                                                  <C>                                      <C> 
             Hugh Y. Rienhoff, Jr., M.D.             Class II Director                        2001
             John P. Walker                          Class II Director                        2001
</TABLE>
<TABLE>

             The  following  Class I and III  Directors  continue to serve their
             respective  terms which expire at the Company's  Annual  Meeting of
             Stockholders in the year as noted:
<CAPTION>

             Name                                    Position                            Term Expires
             ----------------------------------      ---------------------------------   ------------
<S>                                                  <C>                                      <C> 
             Daniel L. Kisner, M.D.                  Class I Director                         2000
             David Schnell, M.D.                     Class I Director                         2000
             Mark B. Skaletsky                       Class I Director                         2000
             Keith A. Bostian, Ph.D.                 Class III Director                       1999
             James E. Rurka                          Class III Director                       1999
</TABLE>

       (c)   The matters  voted upon at the meeting and the voting  results were
             as follows:

<TABLE>
             (i)   The  election of two Class II  Directors  for a term of three
                   years:
<CAPTION>

             Name                                          For                  Against    Abstain  Not Voted
             ---------------------------                ---------               -------    -------  ---------
<S>                                                     <C>                     <C>           <C>   <C>
             Hugh Y. Rienhoff, Jr., M.D.                8,582,585               128,973       -     2,226,934
             John P. Walker                             8,592,285               119,273       -     2,226,934

</TABLE>



                                      -11-
<PAGE>

<TABLE>
<CAPTION>


             (ii)  Approval of amendment to the Company's 1993 Amended Incentive
                   Stock Plan,  increasing  the number of shares of Common Stock
                   reserved for issuance from 1,880,000 to 2,280,000:

                        For                      Against                   Abstain               Not Voted
                     ---------                   -------                   ------                ---------
<S>                                              <C>                       <C>                   <C>      
                     8,141,242                   547,396                   22,920                2,226,934
</TABLE>
<TABLE>

             (iii) Ratification  of the  appointment  of  Ernst &  Young  LLP as
                   independent  auditors for the fiscal year ending December 31,
                   1998:
<CAPTION>

                        For                      Against                   Abstain               Not Voted
                     ---------                   -------                   ------                ---------
<S>                                               <C>                       <C>                  <C>      
                     8,686,515                    13,284                    11,759               2,226,934
</TABLE>

Item 5.      Other Information

             None.

Item 6.      Exhibits and Reports on Form 8-K

     (a)     The following exhibits have been filed with this report:

             10.22  Lease agreement between the Registrant and Portola Land Co. 
                    dated May 1998
             27.1   Financial Data Schedule

     (b)     Reports on Form 8-K.
             No reports on Form 8-K were filed during the quarter ended June 30,
             1998.




                                      -12-
<PAGE>





                                   SIGNATURES




         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  registrant  has duly  caused  this report to be signed on its behalf by the
undersigned, thereunto duly authorized.


Dated:   August 14, 1998




                                MICROCIDE PHARMACEUTICALS, INC.
                                ------------------------------------------------
                                (Registrant)


                                /s/ James E. Rurka
                                ------------------------------------------------
                                President, Chief Executive Officer and Director
                                (principal executive officer)



                                /s/ Matthew J. Hogan
                                ------------------------------------------------
                                Chief Financial Officer
                                (principal financial and accounting officer)




                                      -13-


                   AMERICAN INDUSTRIAL REAL ESTATE ASSOCIATION

            STANDARD INDUSTRIAL/COMMERCIAL SINGLE-TENANT LEASE - NET
                (DO NOT USE THIS FORM FOR MULTI-TENANT BUILDINGS)

1.0 Basic Provisions ("Basic Provisions")

     1.1. Parties:  This Lease ("Lease"),  dated for reference purposes only May
          11, 1998 is made by and between  Portola  Land  Company,  a CA Limited
          Partnership ("Lessor") and Microcide Pharmaceuticals, Inc., a Delaware
          Corporation ("Lessee"), (collectively the "Parties," or individually a
          "Party").

     1.2. Premises:  That  certain real  property,  including  all  improvements
          therein or to be provided by Lessor under the terms of this Lease, and
          commonly  known as 800, 830 and 840-850  Maude  Avenue,  Mountain View
          located  in the  County  of  Santa  Clara,  State  of  California  and
          generally  described as  (describe  briefly the nature of the property
          and, if applicable, the "Project", if the property is located within a
          Project) 800 Maude Avenue,  consisting of  approximately  18,040 s.f.,
          830 Maude Avenue, consisting of approximately 17,415 s.f., and 840-850
          Maude Avenue , consisting of approximately  35,755 s.f. for a total of
          approximately  71,210 s.f., Santa Clara Assessors Parcel #5: 160-54-16
          & 25 and 160-57-12 ("Premises"). (See also Paragraph 2)

     1.3. Term: Five (5) years and 0 months ("Original Term") commencing October
          1,  2000   ("Commencement   Date")  and  ending   September  30,  2005
          ("Expiration Date"). (See also Paragraph 3)

     1.4. Early Possession:  N/A ("Early Possession Date").  (See also Paragraph
          3.2 and 3.3)

     1.5. Base Rent:  $131,739.00 per month ("Base Rent"),  payable on the first
          day of each month commencing October 1, 2000 (See also Paragraph 4)[X]
          If this box is  checked,  there are  provisions  in this Lease for the
          Base Rent to be adjusted.

     1.6. Base  Rent  Paid Upon  Execution:  $ none as Base Rent for the  period
          _______________________.

     1.7. Security  Deposit:   $150,000.00   ("Security  Deposit").   (See  also
          Paragraph 5)

     1.8. Agreed   Use:   Research  &   Development,   etc.  &   administration,
          manufacturing,  laboratory use, storage and all other uses approved by
          the City of Mountain View. (See also Paragraph 6)

     1.9. Insuring Party. Lessor is the "Insuring Party" unless otherwise stated
          herein. (See also Paragraph 8)

     1.10.Real Estate Brokers:  (See also Paragraph 15)

                (a)   Representation:   The   following   real  estate   brokers
          (collectively,  the  "Brokers") and brokerage  relationships  exist in
          this transaction (check applicable boxes):
   
          [ ]   represents Lessor exclusively ("Lessor's Broker");
          [X]   Cornish  &  Carey  Commercial   represents  Lessee   exclusively
                ("Lessee's Broker"); or
          [ ]   represents both Lessor and Lessee ("Dual Agency").

                (b)  Payment to Brokers:  Upon  execution  and  delivery of this
          Lease by both  Parties,  Lessor shall pay to the Broker the fee agreed
          to in  their  separate  written  agreement  (or if  there  is no  such
          agreement,  the sum of ____% of the total Base Rent for the  brokerage
          services rendered by said Broker.

     1.11.Guarantor.  The  obligations  of the Lessee under this Lease are to be
          guaranteed by N/A ("Guarantor"). (See also Paragraph 37)

     1.12.Addenda  and  Exhibits.  Attached  hereto is an  Addendum  or  Addenda
          consisting  of  Paragraphs 50 through 56 and Exhibits N/A all of which
          constitute a part of this Lease.


<PAGE>


2.0 Premises.

     2.1. Letting. Lessor hereby leases to Lessee, and Lessee hereby leases from
          Lessor, the Premises, for the term, at the rental, and upon all of the
          terms,  covenants  and  conditions  set  forth in this  Lease.  Unless
          otherwise  provided  herein,  any  statement of size set forth in this
          Lease,  or that  may  have  been  used in  calculating  rental,  is an
          approximation  which the Parties  agree is  reasonable  and the rental
          based  thereon is not  subject to  revision  whether or not the actual
          size is more or less.

     2.2. (Deleted)

     2.3. Compliance.  If the Applicable  Requirements are hereafter changed (as
          opposed to being in existence at the Start Date, which is addressed in
          Paragraph 6.2(e) below) so as to require during the term of this Lease
          the  construction  of an addition to or an alteration of the Building,
          the remediation of any Hazardous  Substance,  or the  reinforcement or
          other physical  modification of the Building ("Capital  Expenditure"),
          Lessor and Lessee shall allocate the cost of such work as follows:

              (a)  Subject  to   Paragraph   2.3(d)   below,   if  such  Capital
          Expenditures  are  required as a result of the specific and unique use
          of the Premises by Lessee as compared with uses by tenants in general,
          Lessee  shall be fully  responsible  for the cost  thereof,  provided,
          however that if Such Capital  Expenditure is required  during the last
          two (2)  years of this  Lease  and the cost  thereof  exceeds  six (6)
          month's  Base Rent,  Lessee may instead  terminate  this Lease  unless
          Lessor notifies Lessee, in writing, within ten (10) days after receipt
          of  Lessee's  termination  notice  that  Lessor has elected to pay the
          difference between the actual cost thereof and the amount equal to six
          (6) month's  Base Rent.  If Lessee  elects  termination,  Lessee shall
          immediately  cease the use of the Premises which requires such Capital
          Expenditure  and  deliver  to  Lessor  written  notice   specifying  a
          termination   date  at  least  ninety  (90)  days   thereafter.   Such
          termination date shall,  however, in no event be earlier than the last
          day that Lessee could legally utilize the Premises without  commencing
          such Capital Expenditure.

              (b) If such Capital  Expenditure is not the result of the specific
          and  unique use of the  Premises  by Lessee  (such as,  governmentally
          mandated seismic modifications), then Lessor and Lessee shall allocate
          the  obligation  to pay for such costs  pursuant to the  provisions of
          Paragraph 7.1(c); provided,  however, that if such Capital Expenditure
          is  required  during  the last two  years of this  Lease or if  Lessor
          reasonably  determines that it is not economically feasible to pay its
          share  thereof,  Lessor shall have the option to terminate  this Lease
          upon ninety (90) days prior  written  notice to Lessee  unless  Lessee
          notifies  Lessor,  in writing,  within ten (10) days after  receipt of
          Lessor's  termination  notice that  Lessee  will pay for such  Capital
          Expenditure.  If  Lessor  does not  elect to  terminate,  and fails to
          tender its share of any such Capital  Expenditure,  Lessee may advance
          such funds and deduct same,  with  Interest,  from Rent until Lessor's
          share of such  costs  have  been  fully  paid.  If Lessee is unable to
          finance  Lessor's share, or if the balance of the Rent due and payable
          for the remainder of this Lease is not  sufficient to fully  reimburse
          Lessee on an offset  basis,  Lessee  shall have the right to terminate
          this Lease upon thirty (30) days written notice to Lessor.

              (c) Notwithstanding  the above, the provisions  concerning Capital
          Expenditures are intended to apply only to non-voluntary,  unexpected,
          and new  Applicable  Requirements.  If the  Capital  Expenditures  are
          instead  triggered  by Lessee  as a result  of an  actual or  proposed
          change in use,  change in  intensity  of use, or  modification  to the
          Premises  then, and in that event,  Lessee shall be fully  responsible
          for the cost thereof, and Lessee shall not have any right to terminate
          this Lease.

     2.4  Acknowledgements. Lessee acknowledges that: (a) it has been advised by
          Lessor and/or  Brokers to satisfy itself with respect to the condition
          of the Premises (including but not limited to the electrical, HVAC and
          fire  sprinkler  systems,   security,   environmental   aspects,   and
          compliance with Applicable  Requirements),  and their  suitability for
          Lessee's  intended use, (b) Lessee has made such  investigation  as it
          deems  necessary  with  reference  to such  matters  and  assumes  all
          responsibility  therefor  as the same relate to its  occupancy  of the
          Premises, and (c) neither Lessor,  Lessor's agents, nor any Broker has
          made any oral or written representations or warranties with respect to
          said  matters  other  than as set forth in this  Lease.  In  addition,
          Lessor  acknowledges  that:  (a) Broker  has made no  representations,
          promises or warranties  concerning Lessee's ability to honor the Lease
          or

<PAGE>

          suitability  to occupy the  Premises,  and (b) it is Lessor's sole
          responsibility   to  investigate  the  financial   capability   and/or
          suitability of all proposed tenants.

     2.5. Lessee  as Prior  Owner/Occupant.  The  warranties  made by  Lessor in
          Paragraph 2 shall be of no force or effect if immediately prior to the
          Start Date Lessee was occupant of the Premises.  In such event, Lessee
          shall be responsible for any necessary corrective work.

3.0 Term.

     3.1. Term. The Commencement Date, Expiration Date and Original Term of this
          Lease are as specified in Paragraph 1.3

     3.2. (Deleted)

     3.3  Delay  In  Possession.  Lessor  agrees  to use its  best  commercially
          reasonable  efforts to deliver possession of the Premises to Lessee by
          the Commencement  Date. If, despite said efforts,  Lessor is unable to
          deliver  possession  as  agreed,  Lessor  shall not be  subject to any
          liability therefor, nor shall such failure affect the validity of this
          Lease.  Lessee shall not, however, be obligated to pay Rent or perform
          its other obligations until it receives possession of the Premises. If
          possession  is  not  delivered   within  sixty  (60)  days  after  the
          Commencement  Date,  Lessee may,  at its option,  by notice in writing
          within  ten (10) days  after the end of such  sixty  (60) day  period,
          cancel this Lease, in which event the Parties shall be discharged from
          all obligations  hereunder.  If such written notice is not received by
          Lessor within said ten (10) day period, Lessee's right to cancel shall
          terminate. Except as otherwise provided, if possession is not tendered
          to Lessee by the Start Date and Lessee (does not terminate this Lease,
          as aforesaid, any period of rent abatement that Lessee would otherwise
          have  enjoyed  shall run from the date of delivery of  possession  and
          continue  for a  period  equal to what  Lessee  would  otherwise  have
          enjoyed under the terms hereof, but minus any (days of delay caused by
          the acts or omissions of Lessee.  If possession of the Premises is not
          delivered  within four (4) months after the  commencement  Date,  this
          Lease shall  terminate  unless other  agreements  are reached  between
          Lessor and Lessee, in writing.

     3.4  Lessee  Compliance.  Lessor shall not be required to tender possession
          of the Premises to Lessee until Lessee complies with its obligation to
          provide  evidence of insurance  (Paragraph  8.5).  Pending delivery of
          such  evidence,  Lessee  shall  be  required  to  perform  all  of its
          obligations under this Lease from and after the Start Date,  including
          the  payment of Rent,  notwithstanding  Lessees  election  to withhold
          possession pending receipt of such evidence of insurance.  Further, if
          Lessee  is  required  to  perform  any  other  conditions  prior to or
          concurrent  with the Start Date, the Start Date shall occur but Lessor
          may elect to withhold possession until such conditions are satisfied.

4.0 Rent.

     4.1. Rent Defined.  All monetary  obligations of Lessee to Lessor under the
          terms of this Lease (except for the Security Deposit) are deemed to be
          rent ("Rent").

     4.2. Payment.  Lessee shall cause  payment of Rent to be received by Lessor
          in lawful  money of the United  States,  without  offset or  deduction
          (except as specifically permitted in this Lease), on or before the day
          on which it is due.  Rent for any period  during the term hereof which
          is for less than one (1) full calendar  month shall be prorated  based
          upon the actual number of days of said month. Payment of Rent shall be
          made to Lessor at its address  stated  herein or to such other persons
          or place  as  Lessor  may  from  time to time  designate  in  writing.
          Acceptance  of a payment  which is less than the amount then due shall
          not be a waiver  of  Lessor's  rights  to the  balance  of such  Rent,
          regardless of Lessor's endorsement of any check so stating.

5.0  Security  Deposit.  Lessee shall deposit with Lessor upon execution  hereof
     the Security Deposit as security for Lessee's  faithful  performance of its
     obligations  under this Lease.  If Lessee  fails to pay Rent,  or otherwise
     Defaults  under  this  Lease,  Lessor  may use,  apply or retain all or any
     portion of said  Security  Deposit for the payment of any amount due Lessor
     or to reimburse or  compensate  Lessor for any liability  


<PAGE>

     expense, loss or damage which Lessor may suffer or incur by reason thereof.
     If Lessor  uses or applies  all or any  portion of said  Security  Deposit,
     Lessee shall within ten (10) days after written  request  therefor  deposit
     monies with Lessor  sufficient to restore said Security Deposit to the full
     amount  required  by this  Lease.  Should  the  Agreed  Use be  amended  to
     accommodate a material change in the business of Lessee or to accommodate a
     sublessee or assignee, Lessor shall have the right to increase the Security
     Deposit  to the extent  necessary,  in  Lessor's  reasonable  judgment,  to
     account for any  increased  wear and tear that the Premises may suffer as a
     result  thereof.  If a change in control of Lessee occurs during this Lease
     and following such change the financial condition of Lessee is, in Lessor's
     reasonable  judgment,  significantly  reduced,  Lessee  shall  deposit such
     additional  monies with Lessor as shall be sufficient to cause the Security
     Deposit to be at a  commercially  reasonable  level based on said change in
     financial  condition.  Lessor  shall not be required  to keep the  Security
     Deposit separate from its general accounts. Within fourteen (14) days after
     the expiration or termination of this Lease,  if Lessor elects to apply the
     Security Deposit only to unpaid Rent, and otherwise within thirty (30) days
     after the Premises  have been vacated  pursuant to Paragraph  7.4(c) below,
     Lessor  shall  return  that  portion of the  Security  Deposit  not used or
     applied by Lessor.  No part of the Security  Deposit shall be considered to
     be held in trust, to bear interest or to be prepayment for any monies to be
     paid by Lessee under this Lease.

6.0 Use.

     6.1. Use. Lessee shall use and occupy the Premises only for the Agreed Use,
          or any other legal use which is reasonably comparable thereto, and for
          no  other  purpose.  Lessee  shall  not use or  permit  the use of the
          Premises  in a manner that is  unlawful,  creates  damage,  waste or a
          nuisance,  or that  disturbs  owners  and/or  occupants  of, or causes
          damage  to  neighboring  properties.  Lessor  shall  not  unreasonably
          withhold  or  delay  its   consent  to  any  written   request  for  a
          modification  of the Agreed  Use,  so long as the same will not impair
          the structural  integrity of the  improvements  on the Premises or the
          mechanical or electrical  systems therein,  is not significantly  more
          burdensome  to the  Premises.  If Lessor  elects to withhold  consent,
          Lessor  shall  within five (5)  business  days after such request give
          written   notification   of  same,   which  notice  shall  include  an
          explanation of Lessor's objections to the change in use.

     6.2. Hazardous Substances.

                  (a)  Reportable  Uses  Require  Consent.  The term  "Hazardous
              Substance"   as  used  in  this  Lease  shall  mean  any  product,
              substance,  or waste whose presence,  use, manufacture,  disposal,
              transportation,  or  release,  either by itself or in  combination
              with other  materials  expected to be on the Premises,  is either:
              (i) potentially injurious to the public health, safety or welfare,
              the  environment  or the Premises,  (ii) regulated or monitored by
              any  governmental  authority,  or  (iii)  a  basis  for  potential
              liability  of Lessor  to any  governmental  agency or third  party
              under any  applicable  statute  or common  law  theory.  Hazardous
              Substances  shall  include,  but not be limited to,  hydrocarbons,
              petroleum, gasoline, and/or crude oil or any products, by-products
              or fractions  thereof.  Lessee shall not engage in any activity in
              or on the Premises which constitutes a Reportable Use of Hazardous
              Substances without the express prior written consent of Lessor and
              timely  compliance  (at  Lessee's  expense)  with  all  Applicable
              Requirements.  "Reportable Use" shall mean (i) the installation or
              use  of  any  above  or  below  ground  storage  tank,   (ii)  the
              generation,  possession, storage, use, transportation, or disposal
              of a Hazardous  Substance  that  requires a permit  from,  or with
              respect to which a report,  notice,  registration or business plan
              is required to be filed with, any governmental  authority,  and/or
              (iii) the presence at the Premises of a Hazardous  Substance  with
              respect  to which  any  Applicable  Requirements  requires  that a
              notice be given to persons  entering or occupying  the Premises or
              neighboring properties.  Notwithstanding the foregoing, Lessee may
              use any ordinary and customary materials reasonably required to be
              used in the normal  course of the Agreed  Use, so long as such use
              is in  compliance  with  all  Applicable  Requirements,  is  not a
              Reportable  Use, and does not expose the  Premises or  neighboring
              property  to 



<PAGE>

              any meaningful risk of contamination or damage or expose Lessor to
              any  liability  therefor.  In addition,  Lessor may  condition its
              consent  to any  Reportable  Use upon  receiving  such  additional
              assurances as Lessor reasonably deems necessary to protect itself,
              the public,  the Premises and/or the  environment  against damage,
              contamination, injury and/or liability, including, but not limited
              to, the installation (and removal on or before Lease expiration or
              termination)  of  protective   modifications   (such  as  concrete
              encasements) and/or increasing the Security Deposit.

                  (b) Duty to Inform Lessor.  If Lessee knows, or has reasonable
              cause  to  believe,  that a  Hazardous  Substance  has  come to be
              located  in,  on,  under  or about  the  Premises,  other  than as
              previously  consented to by Lessor,  Lessee shall immediately give
              written  notice of such fact to Lessor,  and provide Lessor with a
              copy of any report,  notice, claim or other documentation which it
              has concerning the presence of such Hazardous Substance.

                  (c) Lessee  Remediation.  Lessee shall not cause or permit any
              Hazardous  Substance to be spilled or released in, on,  under,  or
              about the  Premises  (including  through the  plumbing or sanitary
              sewer system) and shall promptly,  at Lessee's  expense,  take all
              investigatory  and/or  remedial  action  reasonably   recommended,
              whether or not formally  ordered or  required,  for the cleanup of
              any  contamination  of, and for the  maintenance,  security and/or
              monitoring  of the Premises or  neighboring  properties,  that was
              caused or materially contributed to by Lessee, or pertaining to or
              involving any Hazardous Substance brought onto the Premises during
              the term of this Lease, by or for Lessee, or any third party.

                  (d) Lessee Indemnification. Lessee shall indemnify, defend and
              hold Lessor, its agents, employees,  lenders and ground lessor, if
              any,  harmless  from and against any and all loss of rents  and/or
              damages, liabilities,  judgments, claims, expenses, penalties, and
              attorneys' and  consultants'  fees arising out of or involving any
              Hazardous Substance brought onto the Premises by or for Lessee, or
              any third party  (provided,  however,  that  Lessee  shall have no
              liability  under this Lease with respect to underground  migration
              of any  Hazardous  Substance  under  the  Premises  from  adjacent
              properties).  Lessee's  obligations  shall  Include,  but  not  be
              limited to, the effects of any  contamination or injury to person,
              property or the environment created or suffered by Lessee, and the
              cost of investigation,  removal,  remediation,  restoration and/or
              abatement, and shall survive the expiration or termination of this
              Lease. No termination,  cancellation or release  agreement entered
              Into  by  Lessor  and  Lessee  shall   release   Lessee  from  its
              obligations under this Lease with respect to Hazardous Substances,
              unless  specifically so agreed by Lessor In writing at the time of
              such agreement.

                  (e)  Lessor  Indemnification.  Lessor and its  successors  and
              assigns shall indemnify,  defend,  reimburse and hold Lessee,  its
              employees  and  lenders,  harmless  from and  against  any and all
              environmental  damages,  including the cost of remediation,  which
              existed as a result of Hazardous  Substances on the Premises prior
              to the Start Date or which are caused by the gross  negligence  or
              willful  misconduct of Lessor,  its agents or employees.  Lessor's
              obligations,  as and when required by the Applicable Requirements,
              shall include,  but not be limited to, the cost of  investigation,
              removal,  remediation,  restoration  and/or  abatement,  and shall
              survive the expiration or termination of this Lease.

                  (f) Investigations  and Remediations.  Lessor shall retain the
              responsibility  and  pay  for any  investigations  or  remediation
              measures  required by governmental  entities  having  Jurisdiction
              with  respect to the  existence  of  Hazardous  Substances  on the
              Premises prior to the Start Date, unless such remediation  measure
              is required as a result of Lessee's use  (including  'Alterations,
              as defined in paragraph  7.3(a) below) of the  Premises,  in which
              event Lessee shall be responsible  for such payment.  Lessee shall
              cooperate  fully in any such  activities at the request of Lessor,
              including  allowing  Lessor and Lessor's agents to have reasonable
              access to the Premises at  reasonable  times in order to carry out
              Lessor's investigative and remedial responsibilities.


<PAGE>

                  (g)  Lessor  Termination  Option.  If  a  Hazardous  Substance
              Condition  occurs during the term of this Lease,  unless Lessee is
              legally responsible  therefor (in which case Lessee shall make the
              investigation  and remediation  thereof required by the Applicable
              Requirements  and this  Lease  shall  continue  in full  force and
              effect,  but subject to Lessor rights under  Paragraph  6.2(d) and
              Paragraph  13),  Lessor  may,  at  Lessor's  option,   either  (i)
              investigate and remediate such Hazardous Substance  Condition,  if
              required,  as soon as reasonably  possible at Lessor's expense, in
              which event this Lease shall continue in full force and effect, or
              (ii) if the estimated  cost to remediate  such  condition  exceeds
              twelve  (12)  times  the  then  monthly  Base  Rent  or  $100,000,
              whichever is greater, give written notice to Lessee, within thirty
              (30) days after  receipt by Lessor of knowledge of the  occurrence
              of such  Hazardous  Substance  Condition,  of  Lessor's  desire to
              terminate  this Lease as of the date sixty (60) days following the
              date  of  such  notice.  In the  event  Lessor  elects  to  give a
              termination  notice,  Lessee may, within ten (10) days thereafter,
              give written  notice to Lessor of Lessee's  commitment  to pay the
              amount  by which  the cost of the  remediation  of such  Hazardous
              Substance  Condition  exceeds an amount equal to twelve (12) times
              the then  monthly  Base Rent or  $100,000,  whichever  is greater.
              Lessee  shall  provide  Lessor  with  said  funds or  satisfactory
              assurance   thereof   within  thirty  (30)  days   following  such
              commitment. In such event, this Lease shall continue in full force
              and effect,  and Lessor shall proceed to make such  remediation as
              soon  as  reasonably   possible   after  the  required  funds  are
              available.  If Lessee  does not give such  notice and  provide the
              required funds or assurance thereof within the time provided, this
              Lease shall  terminate as of the date specified in Lessor's notice
              of termination.

     6.3. Lessee's Compliance with Applicable Requirements.  Except as otherwise
          provided in this Lease, Lessee shall, at Lessee's sole expense, fully,
          diligently  and  in  a  timely  manner,  materially  comply  with  all
          Applicable  Requirements,  the  requirements  of any  applicable  fire
          insurance  underwriter or rating bureau,  and the  recommendations  of
          Lessor's  engineers and/or  consultants  which relate in any manner to
          the Premises,  without regard to whether said  requirements are now in
          effect or become effective after the Start Date. Lessee shall,  within
          ten (10) days  after  receipt of  Lessor's  written  request,  provide
          Lessor  with  copies of all  permits  and other  documents,  and other
          information   evidencing   Lessee's  compliance  with  any  Applicable
          Requirements  specified by Lessor, and shall immediately upon receipt,
          notify Lessor in writing  (with copies of any  documents  involved) of
          any threatened or actual claim, notice, citation,  warning,  complaint
          or report  pertaining  to or  involving  the  failure of Lessee or the
          Premises to comply with any Applicable Requirements.

     6.4. Inspection;  Compliance.  Lessor and Lessor's  "Lender" (as defined in
          Paragraph 30 below) and consultants shall have the right to enter into
          Premises at any time,  in the case of an  emergency,  and otherwise at
          reasonable  times,  for the purpose of inspecting the condition of the
          Premises and for verifying  compliance by Lessee with this Lease.  The
          cost  of any  such  inspections  shall  be paid by  Lessor,  unless  a
          violation of Applicable  Requirements,  or a contamination is found to
          exist or be imminent,  or the  inspection is requested or ordered by a
          governmental  authority.  In such  case,  Lessee  shall  upon  request
          reimburse  Lessor  for the cost of such  inspections,  so long as such
          inspection is reasonably related to the violation or contamination.

7.0 Maintenance; Repairs, Utility Installations; Trade Fixtures and Alterations.

     7.1. Lessee's  Obligation.  *Lessee to be responsible for any required roof
          repair expense due to their own negligence.

                  (a) In General.  Subject to the  provisions  of Paragraph  2.2
              (Condition),  2.3  (Compliance),  6.3  (Lessee's  Compliance  with
              Applicable Requirements), 7.2 (Lessor's Obligations), 9 (Damage or
              Destruction),  and 14  (Condemnation),  Lessee shall,  at Lessee's
              sole  expense,  keep  the  Premises,  Utility  installations,  and
              Alterations  in good order,  condition and repair  (whether or not
              the portion of the  Premises  requiring  repairs,  or the means of
              repairing  the same,  are  reasonably  or  readily  accessible  to
              Lessee,  and whether or not the need for such 

<PAGE>

              repairs  occurs as a result of Lessee's  use,  any prior use,  the
              elements or the age of such portion of the  Premises),  including,
              but not limited to, all equipment or facilities, such as plumbing,
              heating,  ventilating,   air-conditioning,   electrical,  lighting
              facilities,  boilers,  pressure vessels,  fire protection  system,
              fixtures,  walls (interior and exterior),  foundations,  ceilings,
              floors,  windows,  doors,  plate  glass,  skylights,  landscaping,
              driveways, parking lots, fences, retaining walls, signs, sidewalks
              and parkways located in, on, or adjacent to the Premises.  Lessee,
              in keeping the Premises in good order, condition and repair, shall
              exercise  and perform  good  maintenance  practices,  specifically
              including the procurement and maintenance of the service contracts
              required by Paragraph  7.1(b) below.  Lessee's  obligations  shall
              include  restorations,  replacements or renewals when necessary to
              keep the Premises and all  improvements  thereon or a part thereof
              in good order, condition and state of repair. Lessee shall, during
              the  term of this  Lease,  keep  the  exterior  appearance  of the
              Building in a first-class  condition  consistent with the exterior
              appearance of other similar  facilities of comparable age and size
              in  the  vicinity,   including,   when  necessary,   the  exterior
              repainting of the Building.

                  (b) Service Contracts. Lessee shall, at Lessee's sole expense,
              procure  and  maintain  contracts,   with  copies  to  Lessor,  in
              customary   form  and   substance   for,   and  with   contractors
              specializing  and  experienced in the maintenance of the following
              equipment and  improvements,  if any, if and when installed on the
              Premises:  (i) HVAC equipment,  (ii) boiler, and pressure vessels,
              (iii) fire  extinguishing  systems,  including  fire alarm  and/or
              smoke detection, (iv) landscaping and irrigation systems, (v) roof
              covering  and  drains,  (vi)  driveways  and parking  lots,  (vii)
              clarifiers  (viii)  basic  utility  feed to the  perimeter  of the
              Building, and (ix) any other equipment,  if reasonably required by
              Lessor.

                  (c) Replacement. Subject to Lessee's indemnification of Lessor
              as set forth in Paragraph 8.7 below, and without  relieving Lessee
              of  liability  resulting  from  Lessee's  failure to exercise  and
              perform  good  maintenance   practices,   if  the  Basic  Elements
              described in Paragraph  7.1(b) cannot be repaired  other than at a
              cost which is in excess of 50% of the cost of replacing such Basic
              Elements,  then such Basic  Elements  shall be replaced by Lessor,
              and the cost  thereof  shall be  prorated  between the Parties and
              Lessee  shall only be  obligated  to pay,  each  month  during the
              remainder  of the term of this  Lease,  on the date on which  Base
              Rent is due,  an amount  equal to the product of  multiplying  the
              cost of such replacement by a fraction,  the numerator of which is
              one, and the  denominator  of which is the number of months of the
              useful life of such  replacement  as such useful life is specified
              pursuant  to Federal  income tax  regulations  or  guidelines  for
              depreciation   thereof  (including  interest  on  the  unamortized
              balance as is then  commercially  reasonable  in the  judgment  of
              Lessor's  accountants),  with Lessee reserving the right to prepay
              its obligation at any time.

     7.2. Lessor's  Obligations.  Subject to the  provisions,  of Paragraphs 2.2
          (Condition),  2.3  (Compliance),  9  (Damage  or  Destruction)  and 14
          (Condemnation),  it is intended by the Parties hereto that Lessor have
          no obligation,  in any manner  whatsoever,  to repair and maintain the
          Premises,  or the  equipment  therein,  all of which  obligations  are
          intended to be that of the Lessee.  It is the intention of the Parties
          that the terms of this Lease govern the respective  obligations of the
          Parties  as to  maintenance  and  repair  of the  Premises,  and  they
          expressly  waive the benefit of any statute now or hereafter in effect
          to the extent it is inconsistent with the terms of this Lease.

     7.3. Utility Installations; Trade Fixtures; Alterations.

                  (a)   Definitions;   Consent   Required.   The  term  "Utility
              Installations"  refers  to all  floor and  window  coverings,  air
              lines, power panels,  electrical  distribution,  security and fire
              protection systems, communication systems, lighting fixtures, HVAC
              equipment,  plumbing,  and fencing in or on the Premises. The term
              "Trade Fixtures" shall mean Lessee's  machinery and equipment that
              can be removed without doing material damage to the Premises.  The
              term   "Alterations"   shall   mean   any   modification   of  the
              improvements,  other than Utility Installations or Trade Fixtures,
              whether by addition or deletion.  "Lessee Owned Alterations and/or

<PAGE>

              Utility  Installations"  are defined as Alterations and/or Utility
              Installations  made by  Lessee  that are not yet  owned by  Lessor
              pursuant  to   Paragraph   7.4(a).   Lessee  shall  not  make  any
              Alterations  or  Utility  Installations  to the  Premises  without
              Lessor's  prior  written   consent.   Lessee  may  however,   make
              non-structural  Utility  Installations  to  the  interior  of  the
              Premises (excluding the roof) without such consent but upon notice
              to Lessor,  as long as they are not visible from the  outside,  do
              not involve  puncturing,  relocating  or removing  the roof or any
              existing walls,  and the cumulative cost thereof during this Lease
              as extended does not exceed $50,000 in the aggregate or $10,000 in
              any one year.

                  (b) Consent.  Any  Alterations or Utility  Installations  that
              Lessee shall  desire to make and which  require the consent of the
              Lessor shall be presented to Lessor in written form with  detailed
              plans.  Consent shall be deemed  conditioned  upon  Lessee's:  (i)
              acquiring all applicable  governmental  permits,  (ii)  furnishing
              Lessor  with  copies  of  both  the  permits  and  the  plans  and
              specifications  prior  to  commencement  of the  work,  and  (iii)
              compliance   with  all   conditions  of  said  permits  and  other
              Applicable  Requirements in a prompt and expeditious  manner.  Any
              Alterations  or  Utility  Installations  shall be  performed  in a
              workmanlike  manner  with good and  sufficient  materials.  Lessee
              shall promptly upon completion  furnish Lessor with as-built plans
              and  specifications.  For work which costs an amount  equal to the
              greater of one month's Base Rent, or $10,000, Lessor may condition
              its consent upon Lessee providing a lien and completion bond in an
              amount equal to one and one-half  times the estimated cost of such
              Alteration or Utility Installation and/or upon Lessee's posting an
              additional Security Deposit with Lessor.

                  (c)  Indemnification.  Lessee shall pay,  when due, all claims
              for labor or materials furnished or alleged to have been furnished
              to or for Lessee at or for use on the  Premises,  which claims are
              or may be secured by any mechanic's or materialmen's  lien against
              the Premises or any interest therein. Lessee shall give Lessor not
              less than ten (10) days notice  prior to the  commencement  of any
              work in, on or about the Premises, and Lessor shall have the right
              to post notices of non-responsibility. If Lessee shall contest the
              validity of any such lien, claim or demand,  then Lessee shall, at
              its  sole  expense  defend  and  protect  itself,  Lessor  and the
              Premises  against  the same and  shall  pay and  satisfy  any such
              adverse   judgment  that  may  be  rendered   thereon  before  the
              enforcement thereof. If Lessor shall require, Lessee shall furnish
              a surety  bond in an amount  equal to one and  one-half  times the
              amount  of such  contested  lien,  claim or  demand,  indemnifying
              Lessor  against  liability  for the  same.  If  Lessor  elects  to
              participate  in  any  such  action,   Lessee  shall  pay  Lessor's
              attorneys' fees and costs.

     7.4. Ownership; Removal; Surrender; and Restoration.

                  (a) Ownership. Subject to Lessor's right to require removal or
              elect  ownership as  hereinafter  provided,  all  Alterations  and
              Utility  Installations  made by Lessee  shall be the  property  of
              Lessee, but considered a part of the Premises.  Lessor may, at any
              time,  elect in  writing  to be the owner of all or any  specified
              part of the Lessee Owned  Alterations  and Utility  Installations.
              Unless  otherwise  instructed  per Paragraph  7.4(b)  hereof,  all
              Lessee Owned Alterations and Utility  Installations  shall, at the
              expiration or  termination  of this Lease,  become the property of
              Lessor and be surrendered by Lessee with the Premises.

                  (b)  Removal.  By  delivery  to Lessee of written  notice from
              Lessor not earlier than ninety (90) and not later than thirty (30)
              days  prior  to the  end of the  term of this  Lease,  Lessor  may
              require  that  any or all  Lessee  Owned  Alterations  or  Utility
              Installations  be removed by the expiration or termination of this
              Lease.  Lessor may  require  the removal at any time of all or any
              part of any Lessee Owned Alterations or Utility Installations made
              without the required consent.

                  (c) Surrender/Restoration. Lessee shall surrender the Premises
              by the Expiration Date or any earlier  termination  date, with all
              of the  improvements,  parts and surfaces  thereof broom clean and
              free of debris,  and in good operating order,  condition and state
              of repair,  ordinary wear and tear  excepted.  "Ordinary  wear and
              tear"  shall not include  any damage or  deterioration  that
<PAGE>

              would have been  prevented by good  maintenance  practice.  Lessee
              shall   repair  any  damage   occasioned   by  the   installation,
              maintenance or removal of Trade Fixtures, Lessee Owned Alterations
              and/or Utility Installations,  furnishings,  and equipment as well
              as the removal of any storage tank installed by or for Lessee, and
              the removal,  replacement, or remediation of any soil, material or
              groundwater  contaminated  by Lessee.  Trade Fixtures shall remain
              the property of Lessee and shall be removed by Lessee. The failure
              by Lessee to timely vacate the Premises pursuant to this Paragraph
              7.4(c)  without  the  express  written  consent  of  Lessor  shall
              constitute a holdover under the provisions of Paragraph 26 below.

8.0  Insurance; Indemnity.

     8.1. Payment for  Insurance.  Lessee shall pay for all  insurance  required
          under  Paragraph  8 except to the extent of the cost  attributable  to
          liability insurance carried by Lessor under Paragraph 8.2(b) in excess
          of $2,000,000 per occurrence.  Premiums for policy periods  commencing
          prior to or  extending  beyond  the Lease term  shall be  prorated  to
          correspond  to the  Lease  term.  Payment  shall be made by  Lessee to
          Lessor within ten (10) days following receipt of an invoice.

     8.2. Liability Insurance.

                  (a) Carried by Losses. Lessee shall obtain and keep in force a
              Commercial General Liability Policy of Insurance protecting Lessee
              and Lessor against claims for bodily injury,  personal  injury and
              property  damage based upon or arising out of the ownership,  use,
              occupancy or maintenance of the Premises and all areas appurtenant
              thereto.  Such insurance shall be on an occurrence basis providing
              single limit  coverage in an amount not less than  $2,000,000  per
              occurrence  with an  "Additional  Insured-Managers  or  Lessors of
              Premises  Endorsement" and contain the "Amendment of the Pollution
              Exclusion  Endorsement"  for damage caused by heat, smoke or fumes
              from  a  hostile   fire.   The  Policy   shall  not   contain  any
              intra-insured   exclusions   as   between   insured   persons   or
              organizations,  but shall include  coverage for liability  assumed
              under this Lease as an "Insured  contract" for the  performance of
              Lessee's  indemnity  obligations  under this Lease.  The limits of
              said insurance shall not,  however,  limit the liability of Lessee
              nor relieve  Lessee of any  obligation  hereunder.  All  insurance
              carried by Lessee  shall be primary to and not  contributory  with
              any similar insurance carried by Lessor,  whose insurance shall be
              considered excess insurance only.

                  (b)  Carried  by  Lessor.   Lessor  shall  maintain  liability
              insurance as described  in Paragraph  8.2(a),  in addition to, and
              not in lieu of, the insurance required to be maintained by Lessee.
              Lessee shall not be named as an additional insured therein.

     8.3. Property Insurance - Building, Improvements and Rental Value.

                  (a) Building and Improvements. The Insuring Party shall obtain
              and keep in force a policy or policies in the name of Lessor, with
              loss payable to Lessor,  any ground  lessor,  and to any Lender(s)
              insuring  loss or  damage  to the  Premises.  The  amount  of such
              insurance  shall  be equal  to the  full  replacement  cost of the
              Premises, as the same shall exist from time to time, or the amount
              required  by  any   Lenders,   but  in  no  event  more  than  the
              commercially  reasonable and available insurable value thereof. If
              Lessor is the Insuring Party,  however,  Lessee Owned  Alterations
              and Utility  Installations,  Trade Fixtures, and Lessee's personal
              property  shall be insured by Lessee  under  Paragraph  8.4 rather
              than by Lessor.  If the  coverage is  available  and  commercially
              appropriate,  such policy or  policies  shall  insure  against all
              risks of direct  physical  loss or damage  (except  the  perils of
              flood and/or earthquake unless required by any lender),  including
              coverage for debris removal and the  enforcement of any Applicable
              Requirements requiring the upgrading,  demolition,  reconstruction
              or  replacement  of any portion of the Premises as the result of a
              covered loss. Said policy or policies shall also contain an agreed
              valuation provision in lieu of any coinsurance  clause,  waiver of
              subrogation, and inflation guard protection causing an increase in
              the annual property  insurance  coverage amount by a factor of not
              less than the adjusted  U.S. 
<PAGE>

              Department of Labor Consumer  Price Index for All Urban  Consumers
              for the city nearest to where the  Premises  are located.  If such
              insurance  coverage has a deductible clause, the deductible amount
              shall not exceed $1,000 per occurrence, and Lessee shall be liable
              for such deductible amount in the event of an Insured Loss.

                  (b) Rental Value.  The Insuring Party shall obtain and keep in
              force a policy or policies in the name of Lessor with loss payable
              to Lessor and any Lender,  insuring  the loss of the full Rent for
              one (1) year.  Said insurance  shall provide that in the event the
              Lease is terminated  by reason of an insured  loss,  the period of
              indemnity for such coverage  shall be extended  beyond the date of
              the  completion  of repairs or  replacement  of the  Premises,  to
              provide for one full year's loss of Rent from the date of any such
              loss. Said insurance shall contain an agreed  valuation  provision
              in lieu of any  coinsurance  clause,  and the  amount of  coverage
              shall be adjusted annually to reflect the projected Rent otherwise
              payable by Lessee,  for the next twelve (12) month period.  Lessee
              shall be  liable  for any  deductible  amount in the event of such
              loss.

                  (c)  Adjacent  Premises.  It the Premises are part of a larger
              building,  or of a group of  buildings  owned by Lessor  which are
              adjacent to the Premises, the Lessee shall pay for any increase in
              the  premiums  for the  property  insurance  of such  building  or
              buildings if said increase is caused by Lessee's acts,  omissions,
              use or occupancy of the Premises.

     8.4. Lessees Property/Business Interruption Insurance.

                  (a)  Property   Damage.   Lessee  shall  obtain  and  maintain
              insurance  coverage on all of Lessee's  personal  property,  Trade
              Fixtures,  and Lessee Owned Alterations and Utility Installations.
              Such  insurance  shall be full  replacement  cost  coverage with a
              deductible  of not to exceed $1,000 per  occurrence.  The proceeds
              from  any  such  insurance   shall  be  used  by  Lessee  for  the
              replacement of personal property,  Trade Fixtures and Lessee Owned
              Alterations and Utility Installations. Lessee shall provide Lessor
              with written evidence that such insurance is in force.

                  (b)  Business  Interruption.  Lessee shall obtain and maintain
              loss of income  and extra  expense  insurance  in  amounts as will
              reimburse   Lessee  for  direct  or  indirect   loss  of  earnings
              attributable  to all perils  commonly  insured  against by prudent
              lessees in the business of Lessee or attributable to prevention of
              access to the Premises as a result of such perils.

                  (c) No  Representation of Adequate  Coverage.  Lessor makes no
              representation  that the limits or forms of coverage of  insurance
              specified herein are adequate to cover Lessee's property, business
              operations or obligations under this Lease.

     8.5. Insurance  Policies.  Insurance  required herein shall be by companies
          duly licensed or admitted to transact  business in the state where the
          Premises  are  located,  and  maintaining  during  the  policy  term a
          "General  Policyholders Rating" of at least B+, V, as set forth in the
          most current issue of "Bests Insurance Guide", or such other rating as
          may be required by a Lender.  Lessee shall not do or permit to be done
          anything which  invalidates the required  insurance  policies.  Lessee
          shall,  prior to the Start Date, deliver to Lessor certified copies of
          policies of such  insurance or  certificates  evidencing the existence
          and  amounts  of the  required  insurance.  No such  policy  shall  be
          cancelable  or subject to  modification  except after thirty (30) days
          prior written  notice to Lessor.  Lessee  shall,  at least thirty (30)
          days prior to the  expiration of such  policies,  furnish  Lessor with
          evidence  of  renewals  or  "insurance   binders"  evidencing  renewal
          thereof,  or Lessor  may order  such  insurance  and  charge  the cost
          thereof to Lessee,  which  amount shall be payable by Lessee to Lessor
          upon demand.  Such policies  shall be for a term of at least one year,
          or the length of the remaining term of this Lease,  whichever is less.
          If either  Party  shall fail to procure  and  maintain  the  insurance
          required  to be carried by it, the other  Party may,  but shall not be
          required to, procure and maintain the same.

     8.6. Waiver of Subrogation. Without affecting any other rights or remedies,
          Lessee and Lessor each hereby release and relieve the other, and waive
          their entire right to recover damages  against the other,  for loss of
          or damage to its  property  arising  out of or  incident to the perils
          required to be insured against herein. The effect of such releases and
          waivers is not limited by the amount of 



<PAGE>

          insurance  carried  or  required,  or by  any  deductibles  applicable
          hereto.  The Parties agree to have their  respective  property  damage
          insurance  carriers waive any right to subrogation that such companies
          may have against Lessor or Lessee,  as the case may be, so long as the
          insurance is not invalidated thereby.

     8.7. Indemnity. Except for Lessor's gross negligence or willful misconduct,
          Lessee  shall  indemnity,   protect,  defend  and  hold  harmless  the
          Premises,  Lessor and its agents,  Lessor's  master or ground  lessor,
          partners  and  Lenders,  from and against any and all claims,  loss of
          rents and/or  damages,  liens,  judgments,  penalties,  attorneys' and
          consultants'  fees,   expenses  and/or  liabilities  arising  out  of,
          involving,  or in  connection  with,  the use and/or  occupancy of the
          Premises by Lessee.  If any action or  proceeding  is brought  against
          Lessor by reason of any at the  foregoing  matters,  Lessee shall upon
          notice  defend the same at  Lessee's  expense  by  counsel  reasonably
          satisfactory  to Lessor and Lessor shall cooperate with Lessee in such
          defense. Lessor need not have first paid any such claim in order to be
          defended or indemnified.

     8.8. Exemption  of Lessor from  Liability.  Lessor  shall not be liable for
          injury or damage to the person or goods,  wares,  merchandise or other
          property  of  Lessee,  Lessee's  employees,   contractors,   invitees,
          customers, or any other person in or about the Premises,  whether such
          damage  or  injury  is  caused  by  or  results   from  fire,   steam,
          electricity,  gas,  water or  rain,  or from  the  breakage,  leakage,
          obstruction  or  other  defects  of  pipes,  fire  sprinklers,  wires,
          appliances,  plumbing,  HVAC or lighting  fixtures,  or from any other
          cause,  whether  the said  injury or damage  results  from  conditions
          arising  upon the  Premises or upon other  portions of the Building of
          which the Premises are a part, or from other sources or places. Lessor
          shall not be liable for any damages arising from any act or neglect of
          any other  tenant of Lessor.  Notwithstanding  Lessors  negligence  or
          breach of this Lease,  Lessor shall under no  circumstances  be liable
          for injury to  Lessee's  business  or for any loss of income or profit
          therefrom.

9.0 Damage or Destruction.

     9.1. Definitions.

                  (a) "Premises Partial Damage" shall mean damage or destruction
              to the  improvements  on the  Premises,  other than  Lessee  Owned
              Alterations  and Utility  Installations,  which can  reasonably be
              repaired  in six (6) months or less from the date of the damage or
              destruction.  Lessor shall notify Lessee in writing  within thirty
              (30) days from the date of the damage or destruction as to whether
              or not the damage is Partial or Total.

                  (b)  "Premises  Total   Destruction"   shall  mean  damage  or
              destruction to the Premises,  other than Lessee Owned  Alterations
              and  Utility  Installations  and  Trade  Fixtures,   which  cannot
              reasonably  be repaired in six (6) months or less from the date of
              the damage or  destruction.  Lessor shall notify Lessee in writing
              within thirty (30) days from the date of the damage or destruction
              as to whether or not the damage is Partial or Total.

                  (c)  "Insured  Loss"  shall  mean  damage  or  destruction  to
              improvements on the Premises,  other than Lessee Owned Alterations
              and Utility Installations and Trade Fixtures,  which was caused by
              an event  required  to be covered by the  insurance  described  in
              Paragraph  8.3(a),  irrespective  of  any  deductible  amounts  or
              coverage limits involved.

                  (d)  "Replacement  Cost"  shall  mean  the cost to  repair  or
              rebuild  the  improvements  owned  by  Lessor  at the  time of the
              occurrence to their condition existing  immediately prior thereto,
              including demolition, debris removal and upgrading required by the
              operation of Applicable  Requirements,  and without  deduction for
              depreciation.

                  (e) "Hazardous  Substance Condition" shall mean the occurrence
              or  discovery  of a  condition  involving  the  presence  of, or a
              contamination  by, a Hazardous  Substance  as defined in Paragraph
              6.2(a), in, on, or under the Premises.


<PAGE>

     9.2  Partial Damage - Insured Loss. If a Premises Partial Damage that is an
          Insured Loss occurs,  then Lessor shall, at Lessor's  expense,  repair
          such  damage  (but  not  Lessee's   Trade  Fixtures  or  Lessee  Owned
          Alterations and Utility  Installations) as soon as reasonably possible
          and this Lease  shall  continue  in full force and  effect;  provided,
          however,  that Lessee shall, at Lessor's election,  make the repair of
          any damage or destruction the total cost to repair of which is $10,000
          or  less,  and,  in such  event,  Lessor  shall  make  any  applicable
          insurance  proceeds available to Lessee on a reasonable basis for that
          purpose.  Notwithstanding the foregoing, if the required insurance was
          not in force or the  insurance  proceeds are not  sufficient to effect
          such repair, the Insuring Party shall promptly contribute the shortage
          in  proceeds   (except  as  to  the   deductible   which  is  Lessee's
          responsibility) as and when required to complete said repairs.  In the
          event,  however,  such shortage was due to the fact that, by reason of
          the unique nature of the improvements, full replacement cost insurance
          coverage was not commercially  reasonable and available,  Lessor shall
          have no obligation to pay for the shortage in insurance proceeds or to
          fully  restore  the  unique  aspects  of the  Premises  unless  Lessee
          provides  Lessor with the funds to cover same,  or adequate  assurance
          thereof,  within ten (10) days following  receipt of written notice of
          such shortage and request  therefor.  If Lessor receives said funds or
          adequate  assurance thereof within said ten (10) day period, the party
          responsible  for making the  repairs  shall  complete  them as soon as
          reasonably  possible  and this  Lease  shall  remain in full force and
          effect.  If such  funds or  assurance  are not  received,  Lessor  may
          nevertheless  elect by written  notice to Lessee  within ten (10) days
          thereafter to: (i) make such restoration and repair as is commercially
          reasonable with Lessor paying any shortage in proceeds,  in which case
          this Lease shall  remain in full force and effect,  or have this Lease
          terminate thirty (30) days thereafter. Lessee shall not be entitled to
          reimbursement  of any funds  contributed  by Lessee to repair any such
          damage  or  destruction.  Premises  Partial  Damage  due  to flood  or
          earthquake  shall be subject to Paragraph  9.3,  notwithstanding  that
          there may be some insurance coverage, but the net proceeds of any such
          insurance  shall be made  available  for the repairs if made by either
          Party.

     9.3  Partial Damage - Uninsured Loss. If a Premises  Partial Damage that is
          not an Insured  Loss occurs,  unless  caused by a negligent or willful
          act of  Lessee  (in which  event  Lessee  shall  make the  repairs  at
          Lessee's  expense),  Lessor may either: (i) repair such damage as soon
          as reasonably  possible at Lessor's expense, in which event this Lease
          shall continue in full force and effect,  or (ii) terminate this Lease
          by giving  written  notice to Lessee  within  thirty  (30) days  after
          receipt by Lessor of knowledge of the occurrence of such damage.  Such
          termination  shall be effective  sixty (60) days following the date of
          such  notice.  In the event  Lessor  elects to  terminate  this Lease,
          Lessee shall have the right within ten (10) days after  receipt of the
          termination  notice to give  written  notice  to  Lessor  of  Lessee's
          commitment to pay for the repair of such damage without  reimbursement
          from  Lessor.   Lessee  shall  provide   Lessor  with  said  funds  or
          satisfactory  assurance  thereof  within thirty (30) days after making
          such commitment. In such event this Lease shall continue in full force
          and effect,  and Lessor shall  proceed to make such repairs as soon as
          reasonably possible after the required funds are available.  If Lessee
          does not make the required  commitment,  this Lease shall terminate as
          of the date specified in the termination notice.

     9.4  Total  Destruction.  Notwithstanding  any other provision hereof, if a
          Premises Total  Destruction  occurs,  this Lease shall terminate sixty
          (60) days following such Destruction. If the damage or destruction was
          caused by the gross negligence or willful misconduct of Lessee, Lessor
          shall have the right to recover Lessor's  damages from Lessee,  except
          as provided in Paragraph 8.6.

     9.5  Damage Near End of Term. If at any time during the last six (6) months
          of this Lease there is damage for which the cost to repair exceeds one
          (1)  month's  Base Rent,  whether or not an Insured  Loss,  Lessor may
          terminate this Lease  effective  sixty (60) days following the date of
          occurrence  of such damage by giving a written  termination  notice to
          Lessee  within  thirty (30) days after the date of  occurrence of such
          damage.  Notwithstanding the foregoing,  if Lessee at that time has an
          exercisable  option to extend this Lease or to purchase the  Premises,
          then Lessee may preserve this Lease by, (a)
<PAGE>

          exercising  such option and (b) providing  Lessor with any shortage in
          insurance  proceeds (or adequate assurance thereof) needed to make the
          repairs  on or before  the  earlier  of (i) the date which is ten days
          after  Lessee's  receipt of  Lessor's  written  notice  purporting  to
          terminate  this  Lease,  or (ii) the day prior to the date upon  which
          such option expires.  If Lessee duly exercises such option during such
          period and provides Lessor with funds (or adequate  assurance thereof)
          to cover any shortage in insurance proceeds, Lessor shall, at Lessor's
          commercially  reasonable  expense,  repair  such  damage  as  soon  as
          reasonably  possible  and this Lease shall  continue in full force and
          effect. If Lessee fails to exercise such option and provide such funds
          or assurance  during such period,  then this Lease shall  terminate on
          the date specified in the termination notice and Lessee's option shall
          be extinguished.

     9.6  Abatement of Rent; Lessee's Remedies.
                  (a)  Abatement.  In the event of  Premises  Partial  Damage or
              Premises Total Destruction or a Hazardous  Substance Condition for
              which Lessee is not responsible under this Lease, the Rent payable
              by Lessee for the period  required for the repair,  remediation or
              restoration  of such damage shall be abated in  proportion  to the
              degree to which Lessee's use of the Premises is impaired,  but not
              to exceed the proceeds  received from the Rental Value  insurance.
              All other  obligations of Lessee  hereunder  shall be performed by
              Lessee,  and Lessor shall have no  liability  for any such damage,
              destruction, remediation, repair or restoration except as provided
              herein.
                  (b)  Remedies.  If  Lessor  shall be  obligated  to  repair or
              restore the Premises and does not commence,  in a substantial  and
              meaningful way, such repair or restoration within ninety (90) days
              after such obligation shall accrue,  Lessee may, at any time prior
              to the  commencement of such repair or  restoration,  give written
              notice to Lessor  and to any  Lenders  of which  Lessee has actual
              notice, of Lessee's election to terminate this Lease on a date not
              less than sixty (60) days following the giving of such notice.  If
              Lessee  gives such  notice and such repair or  restoration  is not
              commenced  within  thirty (30) days  thereafter,  this Lease shall
              terminate as of the date  specified in said notice.  If the repair
              or  restoration  is commenced  within said thirty (30) days,  this
              Lease shall  continue in full force and effect.  "Commence"  shall
              mean either the unconditional  authorization of the preparation of
              the  required  plans,  or the  beginning of the actual work on the
              Premises, whichever first occurs.

     9.7  Termination-Advance  Payments. Upon termination of this Lease pursuant
          to Paragraph  6.2(g) or Paragraph 9, an equitable  adjustment shall be
          made concerning  advance Base Rent and any other advance payments made
          by Lessee to Lessor.  Lessor shall,  in addition,  return to Lessee so
          much of  Lessee's  Security  Deposit  as has not been,  or is not then
          required to be, used by Lessor.

     9.8  Waive  Statutes.  Lessor and Lessee agree that the terms of this Lease
          shall  govern  the  effect  of any  damage  to or  destruction  of the
          Premises  with  respect  to the  termination  of this Lease and hereby
          waive the  provisions  of any present or future  statute to the extent
          inconsistent herewith.

10.0 Real Property Taxes.

     10.1.Definition of "Real Property  Taxes".  As used herein,  the term "Real
          Property  Taxes" shall  include any form of  assessment;  real estate,
          general,  special,  ordinary or  extraordinary,  or rental levy or tax
          (other than inheritance, personal income or estate taxes); improvement
          bond;  and/or  license fee imposed upon or levied against any legal or
          equitable interest of Lessor in the Premises,  Lessor's right to other
          income  therefrom,   and/or  Lessor's  business  of  leasing,  by  any
          authority  having  the direct or  indirect  power to tax and where the
          funds are generated with  reference to the Building  address and where
          the proceeds so generated  are to be applied by the city,  county,  or
          other  local  taxing  authority  of a  jurisdiction  within  which the
          Premises  are  located.  The term  "Real  Property  Taxes"  shall also
          include any tax,  fee,  levy,  assessment  or charge,  or any increase

<PAGE>

          therein, imposed by reason of events occurring during the term of this
          Lease,  including but not limited to, a change in the ownership of the
          Premises.


10.2.            (a) Payment of Taxes.  Lessee shall pay the Real Property Taxes
          applicable to the Premises  during the term of this Lease.  Subject to
          Paragraph  10.2(b),  all such payments shall be made at least ten (10)
          days prior to any  delinquency  date.  Lessee shall  promptly  furnish
          Lessor with  satisfactory  evidence that such taxes have been paid. If
          any such  taxes  shall  cover any period of time prior to or after the
          expiration or termination of this Lease,  Lessee's share of such taxes
          shall  be  prorated  to  cover  only  that  portion  of the  tax  bill
          applicable  to the period  that this  Iease is in  effect,  and Lessor
          shall reimburse  Lessee for any  overpayment.  If Lessee shall fail to
          pay any required Real Property  Taxes,  Lessor shall have the right to
          pay the same, and Lessee shall reimburse Lessor therefor upon demand.

                 (b) Advance  Payment.  In the event Lessee incurs a late charge
          on any Rent  payment,  Lessor may, at Lessor's  option,  estimate  the
          current Real  Property  Taxes,  and require that such taxes be paid in
          advance to Lessor by Lessee, either: (i) in a lump sum amount equal to
          the installment due, at least twenty (20) days prior to the applicable
          delinquency  date,  or (ii) monthly in advance with the payment of the
          Base Rent. If Lessor elects to require payment monthly in advance, the
          monthly  payment  shall  be an  amount  equal  to  the  amount  of the
          estimated  installment  of  taxes  divided  by the  number  of  months
          remaining  before  the  month  in  which  said   installment   becomes
          delinquent.  When the  actual  amount  of the  applicable  tax bill is
          known,  the amount of such equal  monthly  advance  payments  shall be
          adjusted as required to provide the funds needed to pay the applicable
          taxes.  If the amount  collected by Lessor is insufficient to pay such
          Real Property Taxes when due, Lessee,  shall pay Lessor,  upon demand,
          such  additional  sums as are necessary to pay such  obligations.  All
          moneys paid to Lessor under this  Paragraph may be  intermingled  with
          other moneys of Lessor and shall not bear interest.  In the event of a
          Breach by Lessee in the  performance  of its  obligations  under  this
          Lease,  then any balance of funds paid to Lessor under the  provisions
          of this  Paragraph  may at the  option of  Lessor,  be  treated  as an
          additional Security Deposit.

    10.3. Joint  Assessment.  If  the  Premises  are  not  separately  assessed,
          Lessee's  liability  shall  be an  equitable  proportion  of the  Real
          Property Taxes for all of the land and  improvements  included  within
          the tax parcel assessed, such proportion to be conclusively determined
          by Lessor from the  respective  valuations  assigned in the assessor's
          work sheets or such other information as may be reasonably available.

    10.4. Personal Property Taxes.  Lessee shall pay, prior to delinquency,  all
          taxes  assessed  against  and levied upon  Lessee  Owned  Alterations,
          Utility Installations,  Trade Fixtures, furnishings, equipment and all
          personal  property of Lessee.  When possible,  Lessee shall cause such
          property to be assessed and billed  separately  from the real property
          of Lessor. If any of Lessee's said personal property shall be assessed
          with  Lessor's  real  property,  Lessee  shall  pay  Lessor  the taxes
          attributable  to Lessee's  property within ten (10) days after receipt
          of a written statement.

11.0 Utilities.  Lessee  shall  pay for all  water,  gas,  heat,  light,  power,
     telephone,  trash disposal and other utilities and services supplied to the
     Premises,  together  with any taxes  thereon.  If any such services are not
     separately metered to Lessee, Lessee shall pay a reasonable proportion,  to
     be determined by Lessor, of all charges jointly metered.

12.0 Assignment and Subletting.

    12.1. Lessor's Consent Required.

                  (a)  Lessee  shall  not  voluntarily  or by  operation  of law
              assign, transfer,  mortgage or encumber (collectively,  "assign or
              assignment")  or sublet all or any part of  Lessee's  interest  in
              this  Lease or in the  Premises  without  Lessor's  prior  written
              consent.

<PAGE>

                  (b) A change in the  control  of Lessee  shall  constitute  an
              assignment requiring consent. The transfer, on a cumulative basis,
              of  twenty-five  percent  (25%) or more of the  voting  control of
              Lessee shall constitute a change in control for this purpose.

                  (c)  The   involvement   of  Lessee  or  its   assets  in  any
              transaction,  or series of transactions  (by way of merger,  sale,
              acquisition, financing, transfer, leveraged buy-out or otherwise),
              whether or not a formal  assignment or hypothecation of this Lease
              or  Lessee's  assets  occurs,  which  results or will  result in a
              reduction  of the Net Worth of Lessee  by an amount  greater  than
              twenty-five  percent (25%) of such Net Worth as it was represented
              at the time of the  execution  of this Lease or at the time of the
              most recent  assignment  to which Lessor has  consented,  or as it
              exists  immediately  prior  to said  transaction  or  transactions
              constituting such reduction, whichever was or is greater, shall be
              considered  an  assignment  of this  Lease  to  which  Lessor  may
              withhold  its  consent.  "Net Worth of Lessee"  shall mean the net
              worth of  Lessee  (excluding  any  guarantors)  established  under
              generally accepted accounting principles.

                  (d) An assignment  or subletting  without  consent  shall,  at
              Lessor's  option,  be a Default curable after notice per Paragraph
              13.1(c),  or a  noncurable  Breach  without the  necessity  of any
              notice and grace period. If Lessor elects to treat such unapproved
              assignment  or  subletting  as a  noncurable  Breach,  Lessor  may
              either:  (i) terminate  this Lease,  or (ii) upon thirty (30) days
              written notice,  increase the monthly Base Rent to one hundred ten
              percent  (110%) of the Base Rent then in effect.  Further,  in the
              event of such Breach and rental adjustment, (i) the purchase price
              of any option to purchase  the  Premises  held by Lessee  shall be
              subject to similar adjustment to one hundred ten percent (110%) of
              the price  previously in effect,  and (ii) all fixed and non-fixed
              rental  adjustments  scheduled  during the  remainder of the Lease
              term shall be increased  to One Hundred Ten Percent  (110%) of the
              scheduled adjusted rent.

                  (e) Lessee's remedy for any breach of Paragraph 12.1 by Lessor
              shall be limited to compensatory damages and/or injunctive relief.

    12.2. Terms and Conditions Applicable to Assignment and Subletting.

                  (a)  Regardless  of  Lessor's   consent,   any  assignment  or
              subletting shall not, (i) be effective without the express written
              assumption  by such  assignee or sublessee of the  obligations  of
              Lessee under this Lease,  (ii) release  Lessee of any  obligations
              hereunder,  or (iii) alter the primary liability of Lessee for the
              payment of Rent or for the performance of any other obligations to
              be performed by Lessee.

                  (b)  Lessor  may  accept  Rent  or   performance  of  Lessee's
              obligations  from any person other than Lessee pending approval or
              disapproval of an  assignment.  Neither a delay in the approval or
              disapproval  of  such  assignment  nor the  acceptance  of Rent or
              performance  shall  constitute  a waiver or  estoppel  of Lessor's
              right to exercise its remedies for Lessee's Default or Breach.

                  (c) Lessor's consent to any assignment or subletting shall not
              constitute a consent to any subsequent assignment or subletting.

                  (d) In the event of any  Default or Breach by  Lessee,  Lessor
              may proceed directly against Lessee, any Guarantors or anyone else
              responsible for the performance of Lessee's obligations under this
              Lease,   including  any  assignee  or  sublessee,   without  first
              exhausting  Lessor's  remedies  against any other person or entity
              responsible therefore to Lessor, or any security held by Lessor.

                  (e) Each request for consent to an  assignment  or  subletting
              shall  be in  writing,  accompanied  by  information  relevant  to
              Lessor's   determination  as  to  the  financial  and  operational
              responsibility  and  appropriateness  of the proposed  assignee or
              sublessee,  including  but not limited to the  intended use and/or
              required modification of the Premises, if any, together with a fee
              of $1,000 or ten percent  (10%) of the current  monthly  Base Rent
              applicable to the portion of the Premises  which is the subject of
              the  proposed  assignment  or sublease,  whichever is greater,  as
              consideration   for  Lessor's   considering  and  processing  said
              request.  Lessee  agrees to  provide  Lessor  with  such  other or
              additional  information and/or  documentation as may be reasonably
              requested.


<PAGE>

                  (f) Any assignee of, or sublessee under,  this Lease shall, by
              reason  of  accepting  such   assignment  or  entering  into  such
              sublease,  be deemed to have  assumed  and agreed to  conform  and
              comply  with  each  and  every  term,   covenant,   condition  and
              obligation herein to be observed or performed by Lessee during the
              term of said assignment or sublease,  other than such  obligations
              as  are  contrary  to  or  inconsistent   with  provisions  of  an
              assignment or sublease to which Lessor has specifically  consented
              to in writing.

     12.3 Additional  Terms  and  Conditions   Applicable  to  Subletting.   The
          following terms and conditions shall apply to any subletting by Lessee
          of all or any part of the Premises and shall be deemed included in all
          subleases  under this  Lease  whether  or not  expressly  incorporated
          therein:

                  (a)  Lessee  hereby  assigns  and  transfers  to Lessor all of
              Lessee's interest in all Rent payable on any sublease,  and Lessor
              may collect such Rent and apply same toward  Lessee's  obligations
              under this Lease;  provided,  however,  that until a Breach  shall
              occur in the  performance  of  Lessee's  obligations,  Lessee  may
              collect said Rent. Lessor shall not, by reason of the foregoing or
              any assignment of such  sublease,  nor by reason of the collection
              of Rent,  be deemed  liable to the  sublessee  for any  failure of
              Lessee to perform and comply with any of Lessee's  obligations  to
              such sublessee.  Lessee hereby irrevocably  authorizes and directs
              any such  sublessee,  upon receipt of a written notice from Lessor
              stating  that a  Breach  exists  in the  performance  of  Lessee's
              obligations under this Lease, to pay to Lessor all Rent due and to
              become due under the sublease.  Sublessee shall rely upon any such
              notice from  Lessor and shall pay all Rents to Lessor  without any
              obligation  or right to inquire as to whether such Breach  exists,
              notwithstanding any claim from Lessee to the contrary.

                  (b) In the event of a Breach by  Lessee,  Lessor  may,  at its
              option,  require  sublessee  to attorn to Lessor,  in which  event
              Lessor shall undertake the obligations of the sublessor under such
              sublease  from  the time of the  exercise  of said  option  to the
              expiration of such sublease;  provided,  however, Lessor shall not
              be liable for any prepaid  rents or security  deposit paid by such
              sublessee to such  sublessor or for any prior Defaults or Breaches
              of such sublessor.

                  (c) Any matter  requiring the consent of the sublessor under a
              sublease shall also require the consent of Lessor.

                  (d) No  sublessee  shall  further  assign or sublet all or any
              part of the Premises without Lessors prior written consent.

                  (e)  Lessor  shall  deliver a copy of any notice of Default or
              Breach  by Lessee to the  sublessee,  who shall  have the right to
              cure the  Default  of  Lessee  within  the grace  period,  if any,
              specified  in such  notice.  The  sublessee  shall have a right of
              reimbursement  and  offset  from and  against  Lessee for any such
              Defaults cured by the sublessee.

13.0 Default; Breach; Remedies.

    13.1. Default;  Breach. A "Default" is defined as a failure by the Lessee to
          comply  with or perform  any of the terms,  covenants,  conditions  of
          rules under this Lease. A "Breach" is defined as the occurrence of one
          or more of the following  Defaults,  and the failure of Lessee to cure
          such Default within any applicable grace period:

                  (a) The  abandonment  of the Premises;  or the vacating of the
              Premises  without  providing a  commercially  reasonable  level of
              security,   or  where  the  coverage  of  the  property  insurance
              described in Paragraph 8.3 is jeopardized as a result thereof,  or
              without  providing  reasonable  assurances  to minimize  potential
              vandalism.

                  (b) The  failure of Lessee to make any  payment of Rent or any
              Security Deposit required to be made by Lessee hereunder,  whether
              to Lessor or to a third  party,  when due,  to provide  reasonable
              evidence of insurance or surety bond, or to fulfill any obligation
              under this Lease which  endangers or  threatens  life or property,
              where such  failure  continues  for a period of three (3) business
              days following written notice to Lessee.


<PAGE>

                  (c) The  failure by Lessee to provide (i)  reasonable  written
              evidence of  compliance  with  Applicable  Requirements,  (ii) the
              service   contracts,   (ii)  the  rescission  of  an  unauthorized
              assignment  or  subletting,   (iv)  a  Tenancy  Statement,  (v)  a
              requested  subordination,  (vi) evidence  concerning  any guaranty
              and/or Guarantor,  (vii) any document requested under Paragraph 42
              (easements),  or (viii)  any other  documentation  or  information
              which Lessor may  reasonably  require of Lessee under the terms of
              this Lease,  where any such failure  continues for a period of ten
              (10) days following written notice to Lessee.

                  (d) A Default by Lessee as to the terms, covenants, conditions
              or  provisions  of  this  Lease,  or of the  rules  adopted  under
              Paragraph 40 hereof,  other than those described in  subparagraphs
              13.1 (a), (b) or (c),  above,  where such Default  continues for a
              period  of  thirty  (30)  days  after  written  notice;  provided,
              however,  that if the nature of Lessee's Default is such that more
              than thirty (30) days are reasonably  required for its cure,  then
              it shall not be deemed  to be a Breach  if Lessee  commences  such
              cure within said thirty (30) day period and thereafter  diligently
              prosecutes such cure to completion.

                  (e) The  occurrence  of any of the following  events:  (i) the
              making of any general arrangement or assignment for the benefit of
              creditors;  (ii)  becoming a "debtor" as defined in 11 U.S.C.  ss.
              101 or any successor  statute  thereto  (unless,  in the case of a
              petition filed against Lessee,  the same is dismissed within sixty
              (60) days); (iii) the appointment of a trustee or receiver to take
              possession of substantially  all of Lessee's assets located at the
              Premises or of Lessee's  interest in this Lease,  where possession
              is not  restored to Lessee  within  thirty (30) days;  or (iv) the
              attachment,  execution or other judicial  seizure of substantially
              all of  Lessee's  assets  located at the  Premises  or of Lessee's
              interest  in this  Lease,  where such  seizure  is not  discharged
              within thirty (30) days; provided,  however, in the event that any
              provision of this  subparagraph  (e) is contrary to any applicable
              law, such provision shall be of no force or effect, and not affect
              the validity of the remaining provisions.

                  (f) The discovery that any financial statement of Lessee or of
              any Guarantor given to Lessor was materially false.

                  (g) If the  performance  of  Lessee's  obligations  under this
              Lease  is  guaranteed:  (i) the  death  of a  Guarantor,  (ii) the
              termination of a Guarantor's  liability with respect to this Lease
              other than in accordance with the terms of such guaranty,  (iii) a
              Guarantor's  becoming  insolvent  or the  subject of a  bankruptcy
              filing, (iv) a Guarantor's refusal to honor the guaranty, or (v) a
              Guarantor's  breach of its guaranty  obligation on an anticipatory
              basis,  and Lessee's  failure,  within  sixty (60) days  following
              written notice of any such event, to provide  written  alternative
              assurance or security,  which, when coupled with the then existing
              resources  of Lessee,  equals or exceeds  the  combined  financial
              resources of Lessee and the Guarantors that existed at the time of
              execution of this Lease.

    13.2. Remedies.  If Lessee falls to perform any of its affirmative duties or
          obligations,  within ten (10) days after written notice (or in case of
          an emergency, without notice), Lessor may, at its option, perform such
          duty or  obligation on Lessee's  behalf,  including but not limited to
          the obtaining of reasonably  required bonds,  insurance  policies,  or
          governmental licenses, permits or approvals. The costs and expenses of
          any such performance by Lessor shall be due and payable by Lessee upon
          receipt of Invoice  therefor.  If any check  given to Lessor by Lessee
          shall not be honored by the bank upon  which it is drawn,  Lessor,  at
          its option, may require all future payments to be made by Lessee to be
          by  cashier's  check.  In the event of a Breach,  Lessor may,  with or
          without further notice or demand,  and without  limiting Lessor in the
          exercise  of any right or remedy  which  Lessor  may have by reason of
          such Breach:

                  (a) Terminate  Lessee's right to possession of the Premises by
              any lawful  means,  in which case this Lease shall  terminate  and
              Lessee shall immediately  surrender  possession to Lessor. In such
              event Lessor  shall be entitled to recover  from  Lessee:  (i) the
              unpaid Rent which had been


<PAGE>


              earned at the time of  termination;  (ii) the worth at the time of
              award of the amount by which the unpaid rent which would have been
              earned  after  termination  until  the time of award  exceeds  the
              amount of such rental loss that the Lessee  proves could have been
              reasonably  avoided;  (iii)  the worth at the time of award of the
              amount by which the unpaid  rent for the balance of the term after
              the time of award  exceeds the amount of such rental loss that the
              Lessee  proves  could be  reasonably  avoided;  and (iv) any other
              amount  necessary  to  compensate  Lessor  for all  the  detriment
              proximately   caused  by  the  Lessee's  failure  to  perform  its
              obligations  under this Lease or which in the  ordinary  course of
              things  would be  likely to result  therefrom,  including  but not
              limited  to the cost of  recovering  possession  of the  Premises,
              expenses  of  relating,   including   necessary   renovation   and
              alteration of the Premises,  reasonable  attorneys' fees, and that
              portion of any  leasing  commission  paid by Lessor in  connection
              with this Lease  applicable to the  unexpired  term of this Lease.
              The  worth  at the  time of award  of the  amount  referred  to in
              provision  (iii) of the  immediately  preceding  sentence shall be
              computed by  discounting  such amount at the discount  rate of the
              Federal Reserve Bank of the District within which the Premises are
              located at the time of award  plus one  percent  (1%).  Efforts by
              Lessor to mitigate damages caused by Lessee's Breach of this Lease
              shall not waive Lessor's right to recover  damages under Paragraph
              12.  If  termination  of  this  Lease  is  obtained   through  the
              provisional  remedy of unlawful  detainer,  Lessor  shall have the
              right to recover in such proceeding any unpaid Rent and damages as
              are  recoverable  therein,  or  Lessor  may  reserve  the right to
              recover all or any part  thereof in a separate  suit.  If a notice
              and grace period  required under Paragraph 13.1 was not previously
              given,  a notice to pay rent or quit,  or to perform or quit given
              to  Lessee  under  the  unlawful   detainer   statute  shall  also
              constitute  the notice  required by Paragraph  13.1. In such case,
              the  applicable  grace period  required by Paragraph  13.1 and the
              unlawful detainer statute shall run concurrently,  and the failure
              of Lessee to cure the  Default  within the greater of the two such
              grace periods  shall  constitute  both an unlawful  detainer and a
              Breach of this Lease entitling Lessor to the remedies provided for
              in this Lease and/or by said statute.

                  (b) Continue the Lease and Lessee's  right to  possession  and
              recover  the Rent as it becomes  due,  in which  event  Lessee may
              sublet or assign, subject only to reasonable limitations.  Acts of
              maintenance,  efforts  to  relet,  and/or  the  appointment  of  a
              receiver to protect the Lessor's interests, shall not constitute a
              termination of the Lessee's right to possession.

                  (c) Pursue any other remedy now or hereafter  available  under
              the laws or judicial  decisions of the state  wherein the Premises
              are located.  The  expiration or  termination of this Lease and/or
              the termination of Lessee's right to possession  shall not relieve
              Lessee from liability under any indemnity provisions of this Lease
              as to matters  occurring or accruing  during the term hereof or by
              reason of Lessee's occupancy of the Premises.

    13.3. Inducement  Recapture.  Any agreement for free or abated rent or other
          charges, or for the giving or paying by Lessor to or for Lessee of any
          cash or other bonus, inducement or consideration for Lessee's entering
          into this Lease, all of which concessions are hereinafter  referred to
          as "Inducement  Provisions," shall be deemed conditioned upon Lessee's
          full and  faithful  performance  of all of the  terms,  covenants  and
          conditions  of this Lease.  Upon  Breach of this Lease by Lessee,  any
          such Inducement  Provision shall  automatically be deemed deleted from
          this Lease and of no  further  force or  effect,  and any rent,  other
          charge, bonus,  inducement or consideration  theretofore abated, given
          or  paid by  Lessor  under  such  an  Inducement  Provision  shall  be
          immediately due and payable by Lessee to Lessor,  notwithstanding  any
          subsequent cure of said Breach by Lessee.  The acceptance by Lessor of
          rent or the cure of the Breach which  initiated  the operation of this
          paragraph  shall not be deemed a waiver by Lessor of the provisions of
          this paragraph  unless  specifically so stated in writing by Lessor at
          the time of such acceptance.

    13.4. Late Charges.  Lessee hereby  acknowledges that late payment by Lessee
          of Rent will  cause  Lessor to incur  costs not  contemplated  by this
          Lease, the exact amount of which will be extremely difficult to

<PAGE>

          ascertain.  Such costs include, but are not limited to, processing and
          accounting charges,  and late charges which may be imposed upon Lessor
          by any  Lender.  Accordingly,  if any Rent  shall not be  received  by
          Lessor  within  five (5) days after such  amount  shall be due,  then,
          without  any  requirement  for notice to Lessee,  Lessee  shall pay to
          Lessor a one-time  late charge equal to ten percent (10%) of each such
          overdue  amount.  The  parties  hereby  agree  that such  late  charge
          represents  a fair and  reasonable  estimate of the costs  Lessor will
          incur by reason of such late  payment.  Acceptance of such late charge
          by Lessor shall in no event constitute a waiver of Lessee's Default or
          Breach with respect to such overdue  amount,  nor prevent the exercise
          of any of the other  rights and  remedies  granted  hereunder.  In the
          event  that  a  late  charge  is  payable  hereunder,  whether  or not
          collected,  for three (3) consecutive  installments of Base Rent, then
          notwithstanding any provision of this Lease to the contrary, Base Rent
          shall,  at  Lessor's  option,  become  due and  payable  quarterly  in
          advance.  

     13.5.Interest.  Any monetary payment due Lessor hereunder,  other than late
          charges,  not received by Lessor,  when due as to  scheduled  payments
          (such as Base Rent) or within  thirty (30) days  following the date on
          which it was due for non-scheduled  payment,  shall bear interest from
          the date when  due,  as to  scheduled  payments,  or the  thirty-first
          (31st) day after it was due as to non-scheduled payments. The interest
          ("Interest")  charged shall be equal to the prime rate reported in the
          Wall Street  Journal as published  closest  prior to the date when due
          plus four percent (4%),  but shall not exceed the maximum rate allowed
          by law.  Interest is payable in addition to the potential  late charge
          provided for in Paragraph 13.4.

13.6.     Breach by Lessor.

                 (a) Notice of Breach.  Lessor  shall not be deemed in breach of
          this Lease unless Lessor fails within a reasonable  time to perform an
          obligation  required to be performed  by Lessor.  For purposes of this
          Paragraph,  a  reasonable  time shall in no event be less than  thirty
          (30) days  after  receipt by  Lessor,  and any  Lender  whose name and
          address shall have been furnished  Lessee in writing for such purpose,
          of written notice specifying wherein such obligation of Lessor has not
          been  performed;  provided,  however,  that if the nature of  Lessor's
          obligation  is such  that more than  thirty  (30) days are  reasonably
          required  for its  performance,  then Lessor shall not be in breach if
          performance  is  commenced  within  such  thirty  (30) day  period and
          thereafter diligently pursued to completion.

                 (b)  Performance  by Lessee on Behalf of  Lessor.  In the event
          that neither  Lessor nor Lender cures said breach  within  thirty (30)
          days after receipt of said notice,  or if having  commenced  said cure
          they do not diligently pursue it to completion,  then Lessee may elect
          to cure said breach at Lessee's expense and offset from Rent an amount
          equal to the greater of one month's Base Rent or the Security Deposit,
          and to pay an excess of such expense under protest, reserving Lessee's
          right to reimbursement from Lessor.  Lessee shall document the cost of
          said cure and supply said documentation to Lessor.

14.0 Condemnation.  If the  Premises or any portion  thereof are taken under the
     power of eminent  domain or sold under the threat of the  exercise  of said
     power (collectively  "Condemnation"),  this Lease shall terminate as to the
     part  taken  as of  the  date  the  condemning  authority  takes  title  or
     possession,  whichever first occurs.  If more than ten percent (10%) of any
     building portion of the premises, or more than twenty-five percent (25%) of
     the land area  portion of the premises  not  occupied by any  building,  is
     taken by Condemnation,  Lessee may, at Lessee's option,  to be exercised in
     writing  within ten (10) days after Lessor shall have given Lessee  written
     notice of such  taking (or in the absence of such  notice,  within ten (10)
     days after the condemning authority shall have taken possession)  terminate
     this Lease as of the date the condemning  authority takes such  possession.
     If Lessee does not terminate  this Lease in accordance  with the foregoing,
     this Lease  shall  remain in full force and affect as to the portion of the
     Premises  remaining,  except  that  the  Base  Rent  shall  be  reduced  in
     proportion  to the  reduction  in  utility of the  Premises  caused by such
     Condemnation.  Condemnation awards and/or payments shall be the property of
     Lessor,  whether such award shall be made as compensation for diminution in
     value of the  leasehold,  the  value of the part  



<PAGE>

          taken, or for severance damages; provided,  however, that Lessee shall
          be entitled to any compensation for Lessee's relocation expenses, loss
          of business goodwill and/or Trade Fixtures,  without regard to whether
          or not this Lease is  terminated  pursuant to the  provisions  of this
          Paragraph.  All  Alterations  and  Utility  Installations  made to the
          Premises  by Lessee,  for  purposes  of  Condemnation  only,  shall be
          considered  the property of the Lessee and Lessee shall be entitled to
          any and all compensation which is payable therefor.  In the event that
          this Lease is not  terminated  by reason of the  Condemnation,  Lessor
          shall repair any damage to the Premises caused by such Condemnation.

15.0      Brokers' Fee.

    15.1  (Deleted)

    15.2  (Deleted)

    15.3  Representations  and Indemnities of Broker  Relationships.  Lessee and
          Lessor  each  represent  and  warrant  to the other that it has had no
          dealings  with any  person,  firm,  broker or finder  (other  than the
          Brokers,  if any) in connection with this Lease, and that no one other
          than said named  Brokers is entitled to any  commission or finders fee
          in  connection  herewith.  Lessee and Lessor do each  hereby  agree to
          indemnify,  protect,  defend  and hold  the  other  harmless  from and
          against  liability for compensation or charges which may be claimed by
          any such unnamed  broker,  finder or other  similar party by reason of
          any  dealings  or actions of the  indemnifying  Party,  including  any
          costs,  expenses,  attorneys'  fees  reasonably  incurred with respect
          thereto.

16.0  Estoppel certificates.

                  (a) Each Party (as  "Responding  Party") shall within ten (10)
              days after  written  notice from the other Party (the  "Requesting
              Party") execute, acknowledge and deliver to the Requesting Party a
              statement  in  writing in form  similar  to the then most  current
              "Estoppel  Certificate" form published by the American  Industrial
              Real  Estate  Association,   plus  such  additional   information,
              confirmation  and/or statements as may be reasonably  requested by
              the Requesting Party.

                  (b) If the  Responding  Party shall fail to execute or deliver
              the  Estoppel   Certificate   within  such  ten  day  period,  the
              Requesting Party may execute an Estoppel Certificate stating that:
              (i) the Lease is in full  force and  effect  without  modification
              except as may be represented by the Requesting  Party,  (ii) there
              are no uncured defaults in the Requesting Party's performance, and
              (iii) if Lessor is the Requesting Party, not more than one month's
              rent  has  been  paid  in  advance.   Prospective  purchasers  and
              encumbrancers,  may rely  upon  the  Requesting  Party's  Estoppel
              Certificate,  and the  Responding  Party  shall be  estopped  from
              denying the truth of the facts contained in said Certificate.

                  (c) If  Lessor  desires  to  finance,  refinance,  or sell the
              Premises,  or any part thereof,  Lessee and all  Guarantors  shall
              deliver to any potential lender or purchaser  designated by Lessor
              such  financial  statements as may be reasonably  required by such
              lender  or  purchaser,  including  but  not  limited  to  Lessee's
              financial  statements  for the  past  three  (3)  years.  All such
              financial  statements  shall be received by Lessor and such lender
              or purchaser in confidence and shall be used only for the purposes
              herein set forth.

17.0 Definition of Lessor. The term "Lessor" as used herein shall mean the owner
     or owners at the time in question of the fee title to the Premises,  or, if
     this is a sublease,  of the Lessee's  interest in the prior  lease.  In the
     event of a transfer of Lessor's  title or interest in the  Premises or this
     Lease,  Lessor shall  deliver to the  transferee or assignee (in cash or by
     credit) any unused Security  Deposit held by Lessor.  Except as provided in
     Paragraph 15, upon such transfer or assignment and delivery of the Security
     Deposit, as aforesaid,  the prior Lessor shall be relieved of all liability
     with  respect  to  the  obligations   and/or  covenants  under  this  Lease
     thereafter  to be performed by the Lessor.  Subject to the  foregoing,  the
     obligations  and/or  covenants  in this Lease to be performed by the Lessor
     shall  be   binding   only  upon  the   Lessor  as   hereinabove   defined.
     Notwithstanding  the above,  and subject to the  provisions of Paragraph 20
     below, the original Lessor under this Lease, and all subsequent  holders of
     the  Lessor's  interest in this Lease shall remain  liable and  responsible
     with regard to the potential duties and liabilities of Lessor pertaining to
     Hazardous Substances as outlined in Paragraph 6 above.
<PAGE>

18.0 Severability.  The invalidity of any provision of this Lease, as determined
     by a court of competent  jurisdiction,  shall in no way affect the validity
     of any other provision hereof.

19.0 Days.  Unless  otherwise  specifically  indicated  to the contrary the word
     "days" as used in this Lease shall mean and refer to calendar days.

20.0 Limitation on Liability.  Subject to the  provisions of Paragraph 17 above,
     the  obligations of Lessor under this Lease shall not  constitute  personal
     obligations of Lessor,  the  individual  partners of Lessor or its or their
     individual partners, directors, officers or shareholders,  and Lessee shall
     look  to  the  Premises,  and  to  no  other  assets  of  Lessor,  for  the
     satisfaction  of any  liability of Lessor with  respect to this Lease,  and
     shall not seek recourse against the individual  partners of Lessor,  or its
     or their individual partners,  directors,  officers or shareholders, or any
     of their personal assets for such satisfaction.

21.0 Time of Essence.  Time is of the essence with respect to the performance of
     all  obligations  to be  performed  or observed  by the Parties  under this
     Lease.

22.0 No Prior or Other Agreements;  Broker  Disclaimer.  This Lease contains all
     agreements between the Parties with respect to any matter mentioned herein,
     and no other prior or contemporaneous  agreement or understanding  shall be
     effective.  Lessor and Lessee each  represents  and warrants to the Brokers
     that it has made, and is relying solely upon, its own  investigation  as to
     the nature,  quality,  character and financial  responsibility of the other
     Party to this Lease and as to the  nature,  quality  and  character  of the
     Premises.  Brokers  have no  responsibility  with  respect  thereto or with
     respect to any  default or breach  hereof by either  Party.  The  liability
     (including court costs and Attorneys'  fees), of any Broker with respect to
     negotiation,  execution, delivery or performance by either Lessor or Lessee
     under this Lease or any amendment or  modification  hereto shall be limited
     to an amount up to the fee received by such Broker  pursuant to this Lease;
     provided, however, that the foregoing limitation on each Broker's liability
     shall not be  applicable to any gross  negligence or willful  misconduct of
     such Broker.

23.0 Notices.

    23.1. Notice  Requirements.  All notices required or permitted by this Lease
          shall be in  writing  and may be  delivered  in person  (by hand or by
          courier) or may be sent by regular,  certified or  registered  mail or
          U.S.  Postal  Service  Express  Mail,  with  postage  prepaid,  or  by
          facsimile  transmission,  and  shall be deemed  sufficiently  given if
          served in a manner specified in this Paragraph 23. The addresses noted
          adjacent to a Party's  signature  on this Lease shall be that  Party's
          address  for  delivery  or mailing  of  notices.  Either  Party may by
          written  notice to the other  specify a different  address for notice,
          except that upon  Lessee's  taking  possession  of the  Premises,  the
          Premises shall  constitute  Lessee's address for notice. A copy of all
          notices to Lessor shall be  concurrently  transmitted to such party or
          parties at such  addresses  as Lessor may from time to time  hereafter
          designate in writing.

    23.2. Date of Notice.  Any notice  sent by  registered  or  certified  mail,
          return  receipt  requested,  shall  be  deemed  given  on the  date of
          delivery  shown on the receipt  card, or if no delivery date is shown,
          the  postmark  thereon.  If sent by regular  mail the notice  shall be
          deemed  given  forty-eight  (48) hours after the same is  addressed as
          required herein and mailed with postage prepaid.  Notices delivered by
          United States  Express Mail or overnight  courier that  guarantee next
          day  delivery  shall be deemed  given  twenty-four  (24)  hours  after
          delivery  of the  same  to the  Postal  Service  or  courier.  Notices
          transmitted by facsimile transmission or similar means shall be deemed
          delivered upon telephone  confirmation of receipt,  provided a copy is
          also  delivered  via  delivery  or mail.  If notice is  received  on a
          Saturday,  Sunday or legal holiday, it shall be deemed received on the
          next business day.
<PAGE>

24.0 Waivers. No waiver by Lessor of the Default or Breach of any term, covenant
     or condition hereof by Lessee,  shall be deemed a waiver of any other term,
     covenant or condition  hereof,  or of any  subsequent  Default or Breach by
     Lessee of the same or of any other  term,  covenant  or  condition  hereof.
     Lessor's  consent to, or approval of, any act shall not be deemed to render
     unnecessary  the  obtaining  of Lessor's  consent  to, or approval  of, any
     subsequent  or similar act by Lessee,  or be  construed  as the basis of an
     estoppel to enforce the  provision or  provisions  of this Lease  requiring
     such consent. The acceptance of Rent by Lessor shall not be a waiver of any
     Default or Breach by Lessee.  Any  payment  by Lessee  may be  accepted  by
     Lessor on account  of moneys or damages  due  Lessor,  notwithstanding  any
     qualifying statements or conditions made by Lessee in connection therewith,
     which  such  statements  and/or  conditions  shall be of no force or effect
     whatsoever unless  specifically agreed to in writing by Lessor at or before
     the time of deposit of such payment.

25.0 Recording.  Either  Lessor or Lessee  shall,  upon  request  of the  other,
     execute,  acknowledge  and deliver to the other a short form  memorandum of
     this Lease for recording purposes.  The Party requesting  recordation shall
     be responsible for payment of any fees applicable thereto.

26.0 No Right To  Holdover.  Lessee  has no right to  retain  possession  of the
     Premises or any part thereof  beyond the  expiration or termination of this
     Lease.  In the event that Lessee  holds  over,  then the Base Rent shall be
     increased to one hundred fifty percent  (150%) of the Base Rent  applicable
     during the month  immediately  preceding  the  expiration  or  termination.
     Nothing  contained  herein  shall be  construed as consent by Lessor to any
     holding over by Lessee.

27.0 Cumulative  Remedies.  No  remedy  or  election  hereunder  shall be deemed
     exclusive  but  shall,  wherever  possible,  be  cumulative  with all other
     remedies at law or in equity.

28.0 Covenants and Conditions; Construction of Agreement. All provisions of this
     Lease  to be  observed  or  performed  by  Lessee  are both  covenants  and
     conditions.  In construing this Lease,  all headings and titles are for the
     convenience  of the parties only and shall not be considered a part of this
     Lease.  Whenever  required by the context,  the singular shall include this
     plural and vice versa.  This Lease shall not be construed as if prepared by
     one of the parties, but rather according to its fair meaning as a whole, as
     if both parties had prepared it.

29.0 Binding  Effect;  Choice  of Law.  This  Lease  shall be  binding  upon the
     parties,  their  personal  representatives,  successors  and assigns and be
     governed by the laws of the State in which the Premises  are  located.  Any
     litigation  between  the  Parties  hereto  concerning  this Lease  shall be
     initiated in the county in which the Premises are located.

30.0 Subordination; Attornment; Non-Disturbance.

    30.1. Subordination.  This  Lease and any  Option  granted  hereby  shall be
          subject and subordinate to any ground lease, mortgage,  deed of trust,
          or other  hypothecation  or security device  (collectively,  "Security
          Device"),  now or hereafter  placed upon the Premises,  to any and all
          advances  made  on  the  security   thereof,   and  to  all  renewals,
          modifications,  and extensions thereof. Lessee agrees that the holders
          of any such Security  Devices (in this Lease  together  referred to as
          "Lessor's  Lender")  shall have no liability or  obligation to perform
          any of the  obligations  of Lessor  under this  Lease.  Any Lender may
          elect to have this Lease and/or any Option granted hereby  superior to
          the lien of its Security  Device by giving  written  notice thereof to
          Lessee, whereupon this Lease and such Options shall be deemed prior to
          such  Security  Device,  notwithstanding  the  relative  dates  of the
          documentation or recordation thereof.


<PAGE>

    30.2. Attornment.  Subject to the  non-disturbance  provisions  of Paragraph
          30.3,  Lessee  agrees to  attorn  to a Lender  or any other  party who
          acquires  ownership  of the Premises by reason of a  foreclosure  of a
          Security Device,  and that in the event of such foreclosure,  such new
          owner  shall not:  (i) be liable for any act or  omission of any prior
          lessor or with respect to events  occurring  prior to  acquisition  of
          ownership;  (ii) be subject to any  offsets or defenses  which  Lessee
          might have against any prior  lessor,  or (iii) be bound by prepayment
          of more than one (1) month's rent.

    30.3. Non-Disturbance.  With  respect to Security  Devices  entered  into by
          Lessor after the execution of this Lease,  Lessee's  subordination  of
          this Lease  shall be subject to  receiving a  commercially  reasonable
          non-disturbance  agreement (a  "Non-Disturbance  Agreement")  from the
          Lender  which   Non-Disturbance   Agreement   provides  that  Lessee's
          possession of the Premises,  and this Lease,  including any options to
          extend the term hereof, will not be disturbed so long as Lessee is not
          in Breach  hereof and  attorns to the  record  owner of the  Premises.
          Further,  within  sixty (60) days after the  execution  of this Lease,
          Lessor  shall  use its  commercially  reasonable  efforts  to obtain a
          Non-Disturbance Agreement from the holder of any pre-existing Security
          Device, which is secured by the Premises.  In the event that Lessor is
          unable to provide the Non-Disturbance Agreement within said sixty (60)
          days, then Lessee may, at Lessee's  option,  directly contact Lessor's
          lender and attempt to negotiate  for the  execution  and delivery of a
          Non-Disturbance Agreement.

    30.4. Self-Executing. The agreements contained in this Paragraph 30 shall be
          effective  without the execution of any further  documents;  provided,
          however,  that,  upon  written  request  from  Lessor  or a Lender  in
          connection  with a sale,  financing or  refinancing  of the  Premises,
          Lessee  and Lessor  shall  execute  such  further  writings  as may be
          reasonably   required  to  separately   document  any   subordination,
          attornment  and/or  Non-Disturbance  Agreement  provided  for  herein.

31.0 Attorneys'  Fees.  If any  Party or Broker  brings an action or  proceeding
     involving  the  Premises to enforce the terms  hereof or to declare  rights
     hereunder,  the  Prevailing  Party  (as  hereafter  defined)  in  any  such
     proceeding,  action,  or appeal  thereon,  shall be entitled to  reasonable
     attorneys'  fees. Such fees may be awarded in the same suit or recovered in
     a separate  suit,  whether or not such action or  proceeding  is pursued to
     decision or judgment. The term,  "Prevailing Party" shall include,  without
     limitation,  a Party or Broker who  substantially  obtains  or defeats  the
     relief  sought,  as the case may be,  whether  by  compromise,  settlement,
     judgment,  or the  abandonment by the other Party or Broker of its claim or
     defense. The attorneys' fees award shall not be computed in accordance with
     any  court  fee  schedule,  but  shall  be such as to fully  reimburse  all
     attorneys' fees reasonably incurred. In addition,  Lessor shall be entitled
     to attorneys'  fees,  costs and expenses  incurred in the  preparation  and
     service of notices of Default and  consultations  in connection  therewith,
     whether or not a legal action is subsequently  commenced in connection with
     such Default or resulting Breach.

32.0 Lessor's Access; Showing Premises; Repairs. Lessor and Lessors agents shall
     have  the  right to  enter  the  Premises  at any  time,  in the case of an
     emergency, and otherwise at reasonable times for the purpose of showing the
     same to  prospective  purchasers,  lenders,  or  lessees,  and making  such
     alterations,  repairs,  improvements or additions to the Premises as Lessor
     may deem necessary.  All such activities shall be without abatement of rent
     or  liability  to Lessee.  Lessor may at any time place on the Premises any
     ordinary  "For Sale" signs and Lessor may during the last six (6) months of
     the term hereof  place on the  Premises  any  ordinary  "For Lease"  signs.
     Lessee may at any time place on or about the  Premises  any  ordinary  "For
     Sublease" sign.

33.0 Auctions. Lessee shall not conduct, nor permit to be conducted, any auction
     upon the Premises without Lessor's prior written consent.  Lessor shall not
     be  obligated to exercise any  standard of  reasonableness  in  determining
     whether to permit an auction.

34.0 Signs. Except for ordinary "For Sublease" signs, Lessee shall not place any
     sign upon the Premises without  Lessor's prior written  consent.  All signs
     must comply with all Applicable Requirements.

35.0 Termination;  Merger.  Unless  specifically  stated otherwise in writing by
     Lessor,  the  voluntary  or other  surrender  of this Lease by Lessee,  the
     mutual  termination  or  cancellation  hereof,  or a termination


<PAGE>

     hereof by Lessor for Breach by Lessee,  shall  automatically  terminate any
     sublease or lesser estate in the Premises;  provided,  however, that Lessor
     may  elect  to  continue  any one or all  existing  subtenancies.  Lessor's
     failure  within  ten (10)  days  following  any such  event to elect to the
     contrary by written notice to the holder of any such lesser interest, shall
     constitute  Lessor's election to have such event constitute the termination
     of such interest.


36.0 Consents.  Except as otherwise provided herein,  wherever in this Lease the
     consent of a Party is  required to an act by or for the other  Party,  such
     consent  shall not be  unreasonably  withheld or delayed.  Lessor's  actual
     reasonable  costs and expenses  (including but not limited to  architects',
     attorneys',  engineers'  and  other  consultants'  fees)  incurred  in  the
     consideration  of, or  response  to, a request  by  Lessee  for any  Lessor
     consent,  including  but  not  limited  to  consents  to an  assignment,  a
     subletting or the presence or use of a Hazardous  Substance,  shall be paid
     by Lessee upon receipt of an invoice and supporting documentation therefor.
     Lessor's consent to any act,  assignment or subletting shall not constitute
     an acknowledgment that no Default or Breach by Lessee of this Lease exists,
     nor shall such consent be deemed a waiver of any then  existing  Default or
     Breach, except as may be otherwise specifically stated in writing by Lessor
     at the time of such consent.  The failure to specify  herein any particular
     condition to Lessor's  consent shall not preclude the  imposition by Lessor
     at the time of consent  of such  further  or other  conditions  as are then
     reasonable  with  reference to the  particular  matter for which consent is
     being  given.   In  the  event  that  either  Party   disagrees   with  any
     determination  made by the other  hereunder  and  reasonably  requests  the
     reasons for such  determination,  the  determining  party shall furnish its
     reasons in writing and in  reasonable  detail within ten (10) business days
     following such request.

37.0   Guarantor.

    37.1. Execution.  The  Guarantors,  if any, shall each execute a guaranty in
          the form most  recently  published  by the  American  Industrial  Real
          Estate  Association,  and  each  such  Guarantor  shall  have the same
          obligations as Lessee under this Lease.

    37.2. Default.  It shall constitute a Default of the Lessee if any Guarantor
          fails or  refuses,  upon  request  to  provide:  (a)  evidence  of the
          execution  of the  guaranty,  including  the  authority  of the  party
          signing on Guarantor's behalf to obligate  Guarantor,  and in the case
          of a corporate  Guarantor,  a certified  copy of a  resolution  of its
          board of  directors  authorizing  the  making  of such  guaranty,  (b)
          current financial statements,  (c) a Tenancy Statement, or (d) written
          confirmation that the guaranty is still in effect.


38.0 Quiet Possession.  Subject to payment by Lessee of the Rent and performance
     of all of the  covenants,  conditions and provisions on Lessee's part to be
     observed and performed under this Lease, Lessee shall have quiet possession
     and quiet enjoyment of the Premises during the term hereof.

39.0     Options.

    39.1. Definition.  "Option"  shall mean: (a) the right to extend the term of
          or renew this Lease or to extend or renew any lease that Lessee has on
          other property of Lessor.

    39.2. Options Personal To Original Lessee.  Each Option granted to Lessee in
          this Lease is personal to the original Lessee,  and cannot be assigned
          or exercised by anyone other than said original  Lessee and only while
          the original  Lessee is in full  possession  of the  Premises  and, if
          requested  by  Lessor,  with  Lessee  certifying  that  Lessee  has no
          intention of thereafter assigning or subletting.

    39.3. Multiple Options. In the event that Lessee has any multiple Options to
          extend or renew this Lease, a later Option cannot be exercised  unless
          the prior Options have been validly exercised.

    39.4. Effect of Default on Options.

                  (a) Lessee  shall  have no right to  exercise  an Option:  (i)
              during  the  period  commencing  with the  giving of any notice of
              Default and  continuing  until said Default is cured,  (ii) during
              the period of time any Rent is unpaid  (without  regard to whether
              notice thereof is given  Lessee),  (iii) during the time Lessee is
              in Breach of this Lease, or (iv) in the event that Lessee has been
              given three (3) or more  notices of separate  Default,  whether or
              not the  Defaults  are cured,  during the twelve (12) month period
              immediately preceding the exercise of the Option.


<PAGE>

                  (b) The period of time within which an Option may be exercised
              shall not be extended or enlarged by reason of Lessee's  inability
              to  exercise  an Option  because of the  provisions  of  Paragraph
              39.4(a).

                  (c) An Option shall  terminate  and be of no further  force or
              effect,  notwithstanding  Lessee's due and timely  exercise of the
              Option,  if, after such exercise and prior to the  commencement of
              the  extended  term,  (i) Lessee fails to pay Rent for a period of
              thirty  (30)  days  after  such  Rent  becomes  due  (without  any
              necessity of Lessor to give notice thereof),  (ii) Lessor gives to
              Lessee  three (3) or more notices of separate  Default  during any
              twelve (12) month  period,  whether or not the Defaults are cured,
              or (iii) if Lessee commits a Breach of this Lease.

40.0 Multiple  Buildings.  If the  Premises  are a part of a group of  buildings
     controlled  by Lessor,  Lessee  agrees that it will observe all  reasonable
     rules  and  regulations  which  Lessor  may make  from time to time for the
     management,  safety,  and care of said  properties,  including the care and
     cleanliness of the grounds and including the parking, loading and unloading
     of  vehicles,  and that Lessee  will pay its fair share of common  expenses
     incurred in connection therewith.

41.0 Security  Measures.  Lessee hereby  acknowledges that the rental payable to
     Lessor  hereunder  does not  include  the cost of  guard  service  or other
     security measures,  and that Lessor shall have no obligation  whatsoever to
     provide same. Lessee assumes all  responsibility  for the protection of the
     Premises,  Lessee, its agents and invitees and their property from the acts
     of third parties.

42.0 Reservations.  Lessor  reserves to itself the right,  from time to time, to
     grant, without the consent or joinder of Lessee, such easements, rights and
     dedications  that Lessor deems  necessary,  and to cause the recordation of
     parcel  maps  and  restrictions,   so  long  as  such  easements,   rights,
     dedications,  maps and restrictions do not unreasonably  interfere with the
     use of the  Premises  by  Lessee.  Lessee  agrees  to  sign  any  documents
     reasonably  requested by Lessor to  effectuate  any such  easement  rights,
     dedication, map or restrictions.

43.0 Performance  Under Protest.  If at any time a dispute shall arise as to any
     amount  or sum of money  to be paid by one  Party to the  other  under  the
     provisions  hereof,  the Party against whom the obligation to pay the money
     is asserted shall have the right to make payment  "under  protest" and such
     payment  shall not be  regarded  as a  voluntary  payment  and there  shall
     survive the right on the part of said Party to institute  suit for recovery
     of such sum. If it shall be adjudged that there was no legal  obligation on
     the part of said  Party to pay such  sum or any part  thereof,  said  Party
     shall be  entitled  to  recover  such sum or so much  thereof as it was not
     legally required to pay.

44.0 Authority.  If  either  Party  hereto  is  a  corporation,  trust,  limited
     liability  company,   partnership,   or  similar  entity,  each  individual
     executing this Lease on behalf of such entity  represents and warrants that
     he or she is duly  authorized  to  execute  and  deliver  this Lease on its
     behalf. Each party shall, within thirty (30) days after request, deliver to
     the other party satisfactory evidence of such authority.

45.0 Conflict. Any conflict between the printed provisions of this Lease and the
     typewritten   or  handwritten   provisions   shall  be  controlled  by  the
     typewritten or handwritten provisions.

46.0 Offer.  Preparation  of this  Lease by  either  Party or  their  agent  and
     submission of same to the other Party shall not be deemed an offer to lease
     to the other Party. This Lease is not intended to be binding until executed
     and delivered by all Parties hereto.

47.0 Amendments.  This  Lease may be  modified  only in  writing,  signed by the
     Parties in interest at the time of the modification. As long as they do not
     materially change Lessee's  obligations  hereunder,  Lessee agrees, to make
     such  reasonable  non-monetary  modifications  to  this  Lease  as  may  be
     reasonably  required by a Lender in connection with the obtaining of normal
     financing or refinancing of the Premises.

48.0 Multiple  Parties.  If more than one  person  or entity is named  herein as
     either Lessor or Lessee, such multiple Parties shall have joint and several
     responsibility to comply with the terms of this Lease.


49.0 Mediation and Arbitration of Disputes.  An Addendum requiring the Mediation
     and/or the  Arbitration of all disputes  between the Parties and/or Brokers
     arising out of this Lease is not attached to this Lease.

<PAGE>

LESSOR AND LESSEE HAVE  CAREFULLY READ AND REVIEWED THIS LEASE AND EACH TERM AND
PROVISION  CONTAINED  HEREIN,  AND BY THE  EXECUTION  OF THIS  LEASE  SHOW THEIR
INFORMED AND VOLUNTARY  CONSENT  THERETO.  THE PARTIES HEREBY AGREE THAT, AT THE
TIME THIS LEASE IS EXECUTED, THE TERMS OF THIS LEASE ARE COMMERCIALLY REASONABLE
AND  EFFECTUATE  THE INTENT AND PURPOSE OF LESSOR AND LESSEE WITH RESPECT TO THE
PREMISES.

- --------------------------------------------------------------------------------

ATTENTION:   NO  REPRESENTATION  OR  RECOMMENDATION  IS  MADE  BY  THE  AMERICAN
INDUSTRIAL REAL ESTATE ASSOCIATION OR BY ANY BROKER AS TO THE LEGAL SUFFICIENCY,
LEGAL EFFECT,  OR TAX  CONSEQUENCES OF THIS LEASE OR THE TRANSACTION TO WHICH IT
RELATES. THE PARTIES ARE URGED TO:

1. SEEK ADVICE OF COUNSEL AS TO THE LEGAL AND TAX CONSEQUENCES OF THIS LEASE.

2. RETAIN APPROPRIATE CONSULTANTS TO REVIEW AND INVESTIGATE THE CONDITION OF THE
PREMISES.  SAID INVESTIGATION SHOULD INCLUDE BUT NOT BE LIMITED TO: THE POSSIBLE
PRESENCE OF HAZARDOUS  SUBSTANCES,  THE ZONING OF THE PREMISES,  THE  STRUCTURAL
INTEGRITY,  THE CONDITION OF THE ROOF AND OPERATING SYSTEMS, AND THE SUITABILITY
OF THE PREMISES FOR LESSEE'S INTENDED USE.

WARNING:  IF THE PREMISES IS LOCATED IN A STATE OTHER THAN  CALIFORNIA,  CERTAIN
PROVISIONS  OF THE LEASE MAY NEED TO BE REVISED  TO COMPLY  WITH THE LAWS OF THE
STATE IN WHICH THE PREMISES IS LOCATED.

- --------------------------------------------------------------------------------
<TABLE>

The  parties  hereto,  have  executed  this  Lease at the place and on the dates
specified above their respective signatures.
<CAPTION>
<S>                                                           <C>
Executed at:      Palo Alto, CA                               Executed at:      Mountain View
- -----------------------------------------------------         -----------------------------------------------
on:               May 11, 1998                                on:               May 6, 1998
- -----------------------------------------------------         -----------------------------------------------
By LESSOR:                                                    By LESSEE:
                                                                       Microcide Pharmaceuticals, Inc.
- -----------------------------------------------------         -----------------------------------------------
Portola Land Co.
- -----------------------------------------------------         -----------------------------------------------

By:               /s/ William J. Hurwick                      By:               /s/ Matthew J. Hogan
- -----------------------------------------------------         -----------------------------------------------
Name Printed:  William J. Hurwick                             Name Printed:  Matthew J. Hogan
- -----------------------------------------------------         -----------------------------------------------
Title:            Partner/Property Manager                    Title:            Chief Financial Officer
- -----------------------------------------------------         -----------------------------------------------
Address:                                                      Address:
- -----------------------------------------------------         -----------------------------------------------

- -----------------------------------------------------         -----------------------------------------------
Telephone:  (650) 688-8550                                    Telephone:  (   )
- -----------------------------------------------------         -----------------------------------------------
Facsimile:  (650) 321-0717                                    Facsimile:  (   )
- -----------------------------------------------------         -----------------------------------------------
Federal ID No.                                                Federal ID No.
- -----------------------------------------------------         -----------------------------------------------

</TABLE>

<PAGE>


                                 LEASE ADDENDUM


ADDENDUM TO THE LEASE DATED MAY 11, 1998, BY AND BETWEEN PORTOLA LAND COMPANY, A
CALIFORNIA LIMITED PARTNERSHIP, LANDLORD, AND MICROCIDE PHARMACEUTICALS, INC., A
CALIFORNIA  CORPORATION TENANT, FOR THOSE PREMISES LOCATED AT 800, 830, 840, 850
MAUDE AVENUE, MOUNTAIN VIEW, CALIFORNIA.

50.0 Base Rent:  (Paragraph 1.5): The Base Rent shall be as follows:

           Months of Term           Sq. Ft./NNN                  Base Rent
           --------------           -----------                  ---------

              01-12                71,210 @ $1.85               $ 131,739
              13-24                71,210 @ $1.92               $ 136,723
              25-36                71,210 @ $1.99               $ 141,708
              37-48                71,210 @ $2.06               $ 146,693
              49-60                71,210 @ $2.13               $ 151,677

51.0 Options:  (Paragraph  39) Lessor  shall grant  Lessee one (1) five (5) year
     option to renew the Lease.  Such option  shall be at the then "fair  market
     rent" (FMR) for  comparable  office and R&D  buildings in the Mountain View
     area.  The  definition  of FMR shall be mutually  agreed upon by Lessor and
     Lessee and take into account that the laboratory  improvements  paid for by
     Lessee shall not be used in determining the FMR.

     Lessee must give Lessor no less than nine (9) months prior  written  notice
     of its intent to exercise such lease option extension. It is further agreed
     that the Base Rent for said  lease  option  extension  shall in no event be
     less than the rental  rate of the last month  preceding  such lease  option
     extension.

52.0 Operating Expenses:  In addition to the Base Rent referred to in Paragraphs
     1.5 and 50 respectively,  Lessee shall reimburse Lessor,  when so required,
     for all operating  expenses  incurred in the  maintenance and operations of
     the  Premises,  including,  but not  limited to,  building  and common area
     maintenance (parking,  landscaping,  lighting) costs of insurance, repairs,
     operations,  management (not to exceed 2% of the Base Rent) and real estate
     taxes. Lessee shall have the right to verify all operating expenses.

53.0 Improvements to the Premises by Lessor:  Lessor,  at Lessor's sole cost and
     expense shall  repair,  slurry seal and stripe the parking lot within sixty
     (60)  days  following  commencement  of  the  lease  term,  or as  soon  as
     reasonably possible, weather permitting.

54.0 Assignment  and  Subletting:  (Paragraph  12).  Lessor  reserves the right,
     and/or  option,  conditional  upon  thirty  (30)  days  written  notice  to
     recapture all or part of the premises,  and therefore  terminate the Lease.
     This  provision  shall  apply only in the event that  Lessee  subleases  in
     excess of 18,000 square feet for an aggregate  term,  including  options of
     more than eighteen (18) months. Should Lessor not elect to recapture all or
     part of the  Premises,  then Lessor and Lessee shall split the excess rents
     50%/50% after Lessee has deducted brokerage commissions, if applicable.

55.0 Moveable Equipment, Trade Fixtures: Upon the Lease termination,  Lessee, at
     Lessee's  sole  cost and  expense,  shall  have the  right  to  remove  its
     emergency generator and fume hoods.  Laboratory case work and shelving,  at
     the option of Lessor,  shall remain the property of Lessor.  See Addendum A


<PAGE>

                                 LEASE ADDENDUM



56.0 Lease Execution  Contingency:  This Lease is subject to Lessor  receiving a
     termination  release of any  on-going  rights  that  Quickturn  Systems may
     currently hold with respect to 800 and 830 Maude Avenue.

Landlord:  PORTOLA  LAND COMPANY, A CALIFORNIA LIMITED PARTNERSHIP

By:      /s/ William J. Hurwick                   Date:        May 11, 1998
     --------------------------------------               ----------------------
             William J. Hurwick

Tenant:  MICROCIDE PHARMACEUTICALS, INC., A CALIFORNIA CORPORATION

By:      /s/ Matthew J. Hogan                      Date:        May 6, 1998
     --------------------------------------               ----------------------
             Matthew J. Hogan


<PAGE>


                                   ADDENDUM A

55.0 Moveable Equipment, Trade Fixtures: Upon the Lease termination,  Lessee, at
     Lessee's  sole  cost and  expense,  shall  have the  right  to  remove  the
     following:

     1.  Fume Hoods
     2.  Laboratory Casework and shelving (830 and 800 Maude Avenue only)
     3.  Laboratory casework and shelving at 850 Maude, at the option of Lessor,
         shall remain the property of Lessor.
     4.  RO water system
     5.  Compressed air system
     6.  Vacuum system
     7.  Uninterruptable power supply (UPS)
     8.  Telephone switch
     9.  Environmental rooms
     10. Hazardous Materials Storage Shed
    
Landlord:  PORTOLA  LAND COMPANY, A CALIFORNIA LIMITED PARTNERSHIP

By:       /s/ William J. Hurwick                  Date:        May 11,1998
     --------------------------------------               ----------------------
              William J. Hurwick

Tenant:  MICROCIDE PHARMACEUTICALS INC., A CALIFORNIA CORPORATION

By:       /s/ Matthew J. Hogan                     Date:        May 6,1998
     --------------------------------------               ----------------------
              Matthew J. Hogan


<TABLE> <S> <C>


<ARTICLE>                     5
<CIK>                         0001010915
<NAME>                        Microcide Pharmaceuticals, Inc.
<MULTIPLIER>                                   1,000
       
<S>                             <C>
<PERIOD-TYPE>                   3-MOS
<FISCAL-YEAR-END>                              DEC-31-1998
<PERIOD-START>                                 APR-01-1998
<PERIOD-END>                                   JUN-30-1998
<CASH>                                           2,890
<SECURITIES>                                    31,024
<RECEIVABLES>                                    1,143
<ALLOWANCES>                                         0
<INVENTORY>                                          0
<CURRENT-ASSETS>                                35,839
<PP&E>                                          17,963
<DEPRECIATION>                                   8,182
<TOTAL-ASSETS>                                  46,504
<CURRENT-LIABILITIES>                            4,040
<BONDS>                                              0
                                0
                                          0
<COMMON>                                        64,477
<OTHER-SE>                                       1,532
<TOTAL-LIABILITY-AND-EQUITY>                    46,504
<SALES>                                              0
<TOTAL-REVENUES>                                 2,800
<CGS>                                                0
<TOTAL-COSTS>                                    5,768
<OTHER-EXPENSES>                                     0
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                  12
<INCOME-PRETAX>                                 (2,476)
<INCOME-TAX>                                         0
<INCOME-CONTINUING>                             (2,476)
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                    (2,476)
<EPS-PRIMARY>                                    (0.23)
<EPS-DILUTED>                                    (0.23)
        


</TABLE>


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