CARDIOTECH INTERNATIONAL INC
8-K, EX-2.1, 2000-12-01
PHARMACEUTICAL PREPARATIONS
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Exhibit  2.1


DATED     2000



                      (1)     CARDIOTECH INTERNATIONAL INC

                                       AND

                            (2)     NERVATION LIMITED



                        --------------------------------
                            SHARE PURCHASE AGREEMENT
                                  IN RESPECT OF
                        CARDIOTECH INTERNATIONAL LIMITED
                        --------------------------------


<PAGE>
INDEX TO CLAUSES                                             CLAUSE   PAGE

Interpretation                                                     1     4
Agreement for sale                                                 2    15
Purchase consideration                                             3    15
Conditions                                                         4    15
Completion                                                         5    17
Retention                                                          6    20
Warranties Undertakings and Covenants                              7    21
Provisions of Business Information                                 8    26
Restrictive Covenants                                              9    26
Vendor's Protection                                               10    28
Announcements                                                     11    28
Effect of Completion                                              12    28
Remedies and Waivers                                              13    29
Assignment                                                        14    29
Further Assurance                                                 15    29
Entire Agreement                                                  16    31
Notices                                                           17    31
Confidentiality                                                   18    31
Costs and Expenses                                                19    32
Counterparts                                                      20    32
Invalidity                                                        21    32
Choice of Governing Law                                           22    33
Jurisdiction                                                      23    33
SCHEDULES
---------
Details of the Company                                      Schedule
                                                            1
Warranties                                                  Schedule
                                                            2
Short particulars of  Properties                            Schedule
                                                            3
Vendors' protection provisions                              Schedule
                                                            4
Intellectual Property Rights                                Schedule
                                                            5


<PAGE>
Parent Company Guarantees                                   Schedule
                                                            6
Trade Creditors                                             Schedule
                                                            7
AGREED FORM DOCUMENTS
---------------------
Disclosure Letter
Deed of Assignment
Business Name Licence
CABG Product Development, Supply and Purchase Agreement


CABG Option Agreement
Chronoflex Supply and Purchase Agreement
Chronoflex Patent and Know How Licence-
Escrow Agreement
Power of Attorney in respect of the Shares
Deed of Repayment and Release of Intra Group Indebtedness
Deed of Variation and Release of Parent Company Guarantees
Deed of Resignation and Release
Freemedic Assignment
Letters of Resignation
Deed of Indemnity


<PAGE>
THIS AGREEMENT is made on the                  day of               2000
BETWEEN:

(1)  CARDIOTECH  INTERNATIONAL INC, a US Corporation incorporated under the laws
     of the State of Massachusetts and having its principal place of business at
     78E Olympia Avenue, Woburn, Massachusetts MA 01801 ("the Vendor");

(2)  NERVATION  LIMITED (Company Number : 3961695) whose registered office is at
     5/7 Grosvenor Court, Foregate Street, Chester, CH1 1HG ("the Purchaser").

WHEREAS:

(A)  The Vendor is the legal and  beneficial  owner of the entire  issued  share
     capital of the Company (as defined).

(B)  The Vendor has agreed to sell and the  Purchaser has agreed to purchase the
     Shares (as defined) on the terms and subject to the  conditions  set out in
     this Agreement.

NOW  IT  IS  AGREED  as  follows:-

1.   INTERPRETATION

     1.1. Definition
          -----------

     the following words and  expressions  have the following  meanings,  unless
     they are inconsistent with the context:

<TABLE>
<CAPTION>
<S>                      <C>
"Agreed Form"            means the form agreed between the parties on or prior to the
                         date of this Agreement and initialled for the purpose of
                         identification by their respective solicitors;

"AMEX"                   means the American Stock Exchange;

"Ancillary Document"     means a document between the parties in Agreed Form and
                         to be entered into on or pursuant to Completion;

"Associate"              means any person firm or Company which is a connected
                         person (as defined in Section 839 ICTA) of the Vendor or
                         which is an associated Company of the Vendor within the
                         meaning of Section 416 ICTA but excluding the Company;

"Balance                 means the balance sheet comprising part of the Last
Sheet"                   Accounts;

"Business                means the licence in the Agreed Form to be entered into by
Name Licence"            the Vendor and the Purchaser on Completion ;


<PAGE>
"Business"               means the business of research development, manufacturing
                         and marketing in relation to vascular access grafts and
                         peripheral grafts;

"Business Day"           means a day (other than a Saturday or a Sunday) on which
                         clearing banks are open for business in London;

"Business                means all information know how and records (whether or
Information"             not confidential and in whatever form held) including
                         (without limitation) all formulae, designs, specifications,
                         quality assurance documents, production records,    data,
                         drawings, manuals and instructions and all customer lists,
                         sales information, business plans and forecasts, and all
                         technical or other expertise and all computer software and
                         all accounting and tax records, correspondence, orders and
                         enquiries relating to the Business and any other business
                         carried on by the Company at Completion;
"CABG"                   means the Coronary Artery Bypass Graft known as "Cardio
                         Pass" and developed by the Vendor and/or the Company ;


"CABG Option             means the option agreement in Agreed Form to be entered
Agreement                into on Completion by the Vendor and the Purchaser and
                         giving the Purchaser the option to acquire certain
                         distribution rights in respect of CABG's;

"CABG Supply             means the product development, supply and purchase
Agreement"               agreement - in Agreed Form to be entered into by  the
                         Vendor and the Purchaser on Completion for the
                         manufacture and supply of CABG's;

"Cambrian                means the leasehold property occupied by the Company
House"                   brief details of which are set out in Part II of Schedule 3;


<PAGE>
"Chronoflex"             means the family of bio-durable polymers manufactured by
                         the Vendor in accordance with specific formulations owned
                         by or licensed to the Vendor;

"Chronoflex              means that formulation of Chronoflex referred to in Part II
RC"                      of Schedule 5 and more particularly described in the
                         Chronoflex Supply Agreements and the Ancillary
                         Documents; including the Escrow Agreement;

Chronoflex               means the patent and know how licence in Agreed Form to
Licence                  be entered into on Completion by the Vendor and the
                         Purchaser and licensing to the Purchaser certain rights in
                         respect of Chronoflex RC:

"Chronoflex              means the supply and purchase agreement in Agreed Form
Supply                   to be entered into on Completion by  the Vendor and the
Agreement"               Purchaser for the manufacture and supply of Chronoflex
                         RC, being one of the Retained Rights;

"Companies               means the Companies Act 1985, the Companies Consolidation
Acts"                    (Consequential Provisions) Act 1985, Companies Act
                        1989 and part V of the Criminal Justice Act 1993;

"Company"                means Cardiotech International Limited (Company Number
                         : 3198267) brief details of which are set out in Schedule 1;

"Completion"             means completion of the sale and purchase of the Shares in
                         accordance with Clause 5;

"Completion              means the date of fulfilment of the last of the Conditions,
Date"                    subject always to the other provisions of Clause 4;

"Conditions"             means those conditions precedent to Completion and more
                         particularly set out in Clause 4;


<PAGE>
"Deed               of   means the deed of assignment between the Vendor and the
Assignment"              Purchaser in respect of the Transferred  Rights in the
                         Agreed Form;

"Deed               of   means the deed of indemnity between the Vendor, the
Indemnity"               purchaser and the Company in respect of the Intellectual
                         Property Rights and in the Agreed Form;

"Deed               of   means the deed of repayment and  release of intra group
Release"                 indebtedness in the Agreed Form;

"Deed               of   means the deed of resignation and release between Alan
Resignation"             Edwards and the Vendor in the Agreed Form;

"Deed               of   means the deed of variation releasing the Vendor from its
 Variation"              obligations under the  Parent Company Guarantees in the
                         Agreed form;

"Disclosure              the bundle of copy documents in Agreed Form and annexed
Bundle"                  to the Disclosure Letter;

"Disclosure              means the disclosure letter of the same date as this
Letter"                  Agreement from the Vendor to the Purchaser in the Agreed
                         form;.

"Dollar                  means the amount in US dollars resulting or that would
Equivalent"              result from the conversion of the relevant amount in
                         Sterling at the relevant date;

"Existing                means  all Intellectual Property used in connection with or
Rights"                  otherwise relating to the Business and  presently vesting in
                         the Company, including but not limited to those rights,
                         more particularly set out in Part I of Schedule 5;

Escrow Agreement         means the Agreement to be entered into on Completion
                         between the Vendor, the Purchaser and the National
                         Computing Centre:


<PAGE>
"FA"                     means Finance Act;
"Freemedic               means the  -deed of  assignment- between the -Vendor
Assignment -             Freemedic and the Purchaser- -and in the Agreed Form:
                                                      ------------------------
"ICTA"                   Income and Corporation Taxes Act 1988;

"Information             means computer hardware, software, networks and/or any
Technology"              aspect of a business which relies on computer hardware,
                         software, networks and/or other information technology
                         (whether embedded or otherwise);

"Intellectual Property"  means any patents, trade marks, service marks, registered
                         designs, utility models, design rights, formulae,
                         specifications, copyright (including any copyright in
                         computer software), database rights, inventions, trade
                         secrets and other confidential information, know how, and
                         all other intellectual and industrial property and rights of a
                         similar or corresponding nature in any part of the world,
                         whether registered or not or capable of registration or not
                         and including the right to apply for and all applications for
                         any of the foregoing rights and the right to sue for
                         infringement of any of the foregoing rights;

"Intellectual            means together the  Retained Rights, the Existing Rights
Property                 and the Transferred Rights;
Rights"

"Intra Group             means all debts liabilities or obligations outstanding as at
Indebtedness"            Completion owed by the Company - on the one hand to the
                         Vendor or any of its Associates on the other hand and vice
                         versa;

"Investment              means those documents between inter alia the Purchaser,
Documents"               3i's and Freemedic  which will put the Purchaser in
                         sufficient funds to complete its obligations under this
                         Agreement;

"ITA"                    Inheritance Tax Act 1984;


<PAGE>
"Last                    the financial statement of the Company prepared in
Accounts"                accordance with UK generally accepted accounting
                         principals for the accounting reference period ended on the
                         Last Accounts Date, which financial statements comprise an
                         audited balance sheet, profit and loss account, notes and
                         auditors and directors reports, copies of which are
                         scheduled to the Disclosure Letter;

"Last Accounts           31st March 2000;
Date"

"Loan"                   means the intra group loan due from the Company to the
                         Vendor in the sum of [ 1,671,659] and to be capitalized
                         prior to Completion;

"3i's"                   means 3i Plc, 91 Waterloo Road, London, SE1 8XP;

"Management              means the management accounts of the Company prepared
Accounts"                for the period up to the Management Accounts Date;

"Management              means 30th September 2000;
Accounts
Date"

"Myolink"                means the trade mark of the same name and being a
                         Transferred Right;



"Parent                  means those guarantees and share options given by the
Company                  Vendor in respect of the liabilities of the Company and
Guarantees"              more particularly set out in Schedule 6
"Part I                  means those warranties set out in Part I of Schedule 2;
Warranties"

"Part II                 means those warranties set out in Part II of Schedule 2;
Warranties"

"Polymedica"             means Polymedica Industries Inc. of State Street, Woburn,
                         Massachusetts, USA;


<PAGE>
"Properties"             means together Tarvin Sands and Cambrian House;

"Purchaser's             means BDO Stoy Hayward  of
Accountants"             St Peter House, St Peter Street,  Manchester, M1 5BH;

"Purchaser's             means Aaron & Partners of 5/7 Grosvenor Court, Foregate
Solicitors"              Street, Chester, CH1 1HG;

"Retained                means those Intellectual Property Rights remaining with the
Rights"                  Vendor following Completion and more particularly set out
                         in Part II of Schedule 7;

"SEC"                    means the US Securities and Exchange Commission;

"Shares"                 means the  entire issued and allotted share capital of the
                         Company at Completion;

"Sterling                means the amount in sterling resulting or that would result
Equivalent"              from the conversion of the relevant amount in US dollars on
                         the relevant date;

"Subsidiary"             shall have the meanings given to them in S736 Companies
and "Holding             Act 1985;
Company"

"Tarvin Sands"           means the property formerly occupied by the Company,
                         brief details of which are set out in Part I of Schedule 3;


<PAGE>
"Tax or                  means
Taxation"                (a)   within the United Kingdom, corporation tax,
                               advance corporation tax, income tax (including income tax
                               required to be deducted or withheld from or accounted
                               for in respect of any payment), capital gains tax,
                               development land tax, capital transfer tax, inheritance
                               tax, value added tax, national insurance contributions,
                               capital duty, stamp duty reserve tax, duties of customs
                               and excise, any liability arising under section 601 of the
                               Income and Corporation Taxes Act 1988, and any other
                               taxes, levies, duties, charges, imposts or withholdings
                               corresponding to, similar to, replaced by or replacing any
                               of them, together with all penalties, charges and interest
                               relating to any of them or to any failure to file any return
                               required for the purposes of any of them; and
                         (b)   outside the United Kingdom, all taxes, levies,
                               duties, imposts, charges - and withholdings of any nature
                               whatsoever, including (without limitation) taxes on gross or
                               net income, profits or gains and taxes on receipts,
                               sales, use, occupation, franchise, value added and
                               personal property, together with all penalties, charges
                               and interest relating to any of them
                         regardless (in either case) of whether any such taxes, levies,
                         duties, imposts, charges, withholdings, penalties and interest
                         are chargeable directly or primarily against or attributable
                         directly or primarily to the Company or any other person
                         and of whether any amount in respect of any of them is
                         recoverable from any other person;

"Taxation                means any taxing or other authority (whether within or
Authority"               outside the United Kingdom) competent to impose any
                         liability in respect of Tax;

"Taxation                includes statutes (and all Regulations and arrangements
Statutes"                whatsoever made thereunder) whether of the United
                         Kingdom or elsewhere and whether enacted before or after
                         the date of this Agreement, providing for or imposing any
                         Taxation;


<PAGE>
"TCGA"                   means the Taxation of Chargeable Gains Act 1992;

"Territory"              means anywhere in the world;


"Thermedics"             means Thermedics Inc, being a joint owner with Polymedica
                         of Patent no. USA5254662;

"Trade                   means those creditors set out in Schedule 7 where the
Creditors"               liability for payment of the amounts set out in that schedule
                         has been assumed by the Vendor;

"Transferred             means all Intellectual Property used in connection with or
Rights"                  otherwise relating to the Business, including but not limited
                         to those rights more particularly set out in Part III of
                         Schedule 7 but excluding the Retained Rights and Existing
                         Rights;

"Vasculink"              means the trade mark of the same name and being a
                         Transferred Right;

"VATA"                   means Value Added Tax Act 1994;

"Vendor's                means Wacks Caller of Steam Packet House, 76 Cross
Solicitors"              Street, Manchester, M2 7JU;

"Warranties"             means the warranties set out in Clause 7 and Parts I and II
                         of Schedule 2 and given by the Vendor and "Warranty"
                         shall be construed accordingly.
</TABLE>


     1.2.

          1.2.1. all references to a statutory  provision  shall be construed as
               including references to:

               (a)  any statutory  modification,  consolidation  or re-enactment
                    (whether before or after the date of this agreement) for the
                    time being in force;


<PAGE>
               (b)  all  statutory  instruments  or orders  made  pursuant  to a
                    statutory  provision;  any  statutory  provisions of which a
                    statutory  provision  is a  consolidation,  re-enactment  or
                    modification;

          1.2.2. any reference to the Vendor includes,  where  appropriate,  its
               successors and assigns;

          1.2.3. a  reference  to an  SSAP  is a  reference  to a  Statement  of
               Standard  Accounting  Practice   established  by  the  Accounting
               Standard Board;

          1.2.4. except where the context otherwise  requires words denoting the
               singular  include the plural and vice versa;  words  denoting any
               one gender include all genders;  words denoting  persons  include
               firms and corporations and vice versa;

          1.2.5. unless otherwise  stated, a reference to a clause or sub-clause
               or a Schedule is a reference  to a clause or  sub-clause  of or a
               Schedule to this agreement.

     1.3. Clause headings in this agreement and in the Schedules are for ease of
          reference only and do not affect the construction of any provision.

2.   AGREEMENT FOR SALE

     2.1. Subject to the terms of this  Agreement,  the  Vendor  shall sell with
          full title  guarantee and the Purchaser shall purchase the Shares free
          from all claims,  liens,  charges,  encumbrances and equities and with
          all rights attaching to them with effect from the Completion Date.

     2.2. For  the   avoidance  of  doubt,   Part  1  of  the  Law  of  Property
          (Miscellaneous  Provisions)  Act 1994 shall not apply for the purposes
          of this Clause.

3.   CONSIDERATION

The  consideration  for the Shares shall be the sum of $2,900,000or the Sterling
     Equivalent which shall be paid by the Purchaser to the Vendor in accordance
     with the provision of Clause 5.4 below.

4.   CONDITIONS

     4.1. Completion of this Agreement is in all respects  conditional  upon the
          following:

          4.1.1.  confirmation  of a resolution  having been being passed by the
               holders  in  excess  of 50% of the  common  stock  of the  Vendor
               approving in principle the transaction proposed hereby;

          4.1.2. a letter in a form satisfactory to the Purchaser being provided
               by Dresdner Kleinwort Benson and consenting to the aforementioned
               principal terms;

          4.1.3. an opinion being provided to the Purchaser by such party and in
               such form as the Purchaser shall reasonably require that:-

               4.1.3.1.  all legal  and  beneficial  rights  to the  Transferred
                    Rights vest in the Vendor absolutely;

               4.1.3.2. the Transferred Rights are freely  transferable into the
                    name of the  Purchaser in  accordance  with the term of this
                    Agreement and the Deed of Assignment;


<PAGE>
               4.1.3.3. all Intellectual Property in respect of Chronoflex RC is
                    immediately  prior to  Completion  legally and  beneficially
                    owned by the  Vendor  and that  such  Intellectual  Property
                    includes the trade secrets  relating to the  formulation and
                    manufacture of Chronoflex RC

               4.1.3.4. the Vendor is legally and beneficially entitled to grant
                    to the Purchaser in respect of the Retained Rights under USA
                    Patent no.  5254662 the rights  specified  in the  Ancillary
                    Documents.;

          4.1.4. a legal  opinion from the Vendor's US  Securities  Counsel in a
               form  satisfactory  to, and addressed to the  Purchaser  that the
               terms of the Agreement and the  Ancillary  Documents  comply with
               and have been approved by all regulatory bodies including but not
               limited  to  AMEX  and  the  SEC or  that  no  such  approval  is
               necessary;

          4.1.5.  the  completion  by the  parties  thereto  of  the  Investment
               Documents;

          4.1.6. the  capitalisation  by the Vendor and the Company of the Loan;
               and

          4.1.7. the  completion  by the parties  named therein of the Freemedic
               Assignment-

     4.2. Each party  shall use its  reasonable  endeavours  to ensure that this
          Agreement becomes  unconditional by the date specified in Clause 4.4.2
          below,  and will notify the Purchaser  forthwith upon the satisfaction
          of such Conditions.

     4.3. The Purchaser shall be entitled to rescind this agreement by notice in
          writing  to the  Vendors  or  the  Vendors'  Solicitors  if  prior  to
          Completion  it appears  that any of the  Warranties  is not or was not
          true and  accurate  in all  material  respects  or if any act or event
          occurs which, had it occurred before the date of this Agreement, would
          have  constituted  a  breach  of any of the  Warranties  which  (being
          capable of remedy) is not remedied prior to Completion.

     4.4. If:-

          4.4.1. any fact which would prevent any Condition from being satisfied
               (whether it does so because of any disclosure made in Clause 7-.4
               or not) comes to the knowledge of the Purchaser; or

          4.4.2. any other  conditions  is not  fulfilled  (notwithstanding  the
               required  best  endeavours  in Clause 4.2) or waived on or before
               17th-  November  2000;  either party the  Purchaser may terminate
               this  Agreement at any time  thereafter by written  notice to the
               other.

     4.5. The Purchaser may waive any of the  Conditions or extend the period in
          which such  conditions are to be satisfied by notice in writing to the
          Vendor or the Vendor's Solicitors.


<PAGE>
5.   COMPLETION

     5.1. Provided that this Agreement has not been rescinded in accordance with
          Clause 4 Completion shall take place at the offices of the Purchaser's
          Solicitors within 2 working days after this Agreement has ceased to be
          conditional  under  Clause 4.1 when all the matters  mentioned  in the
          following sub-clauses shall take place.

     5.2. The Vendor shall deliver to the Purchaser:

          5.2.1. a duly completed and signed transfer in favour of the Purchaser
               (or as it may direct) in respect of the Shares  together with the
               share certificate therefor.

          5.2.2. the  resignations  of the  directors  (other than Alan Edwards)
               from  their  respective  offices in the  Company,  with a written
               acknowledgement  from each of them in -agreed form that he has no
               claim  against  the  Company in  respect  of breach of  contract,
               compensation for loss of office, redundancy,  unfair dismissal or
               on any other grounds whatsoever;

          5.2.3.  the  statutory  books  of the  Company  - its  certificate  of
               incorporation and company seal (if any);

          5.2.4. the title  deeds if any,  relating to the  Company's  leasehold
               interest in the Property;

          5.2.5. the appropriate forms to amend the mandate given by the Company
               to its bankers;

          5.2.6. a duly executed power of attorney in the Agreed Form;

          5.2.7. a duly executed print of the CABG Supply Agreement;

          5.2.8. a duly executed print of the CABG Option Agreement;

          5.2.9. a duly executed print of the Business Name Licence;

          5.2.10. a duly executed print of the Chronoflex Supply Agreement;

          5.2.11. a duly executed print of the Chronoflex Licence

          5.2.12. all other  records,  lists,  information  and data  whether in
               respect  of  customers,   suppliers,  taxation  or  otherwise  in
               relation  to the  Business  which  are in the  possession  of the
               Vendor, including but limited to the Business Information;

          5.2.13. a duly executed print of the Deed of Assignment;

          5.2.14. a duly executed print of the Deed of Release;

          5.2.15. a duly executed print of the Freemedic Assignment; and

          5.2.16. a duly executed print of the Deed of Indemnity.

     5.3. A Board meeting of the Company shall be held at which:

          5.3.1. such persons as the Purchaser  may nominate  shall be appointed
               additional directors;

          5.3.2. the Company  shall procure the delivery to the Vendor of a duly
               executed print of the Deed of Release ;

          5.3.3. the  transfer  referred  to in clause  5.2.1  shall be approved
               (subject to stamping); and

          5.3.4.  the  resignations  referred  to  in  clauses  5.2.2  shall  be
               submitted and accepted.

     5.4. Upon  completion  of the  matters  referred  to in clauses  5.1 to 5.3
          (inclusive);

          5.4.1. the Purchaser shall provide to the Vendor's Solicitors:-


<PAGE>
               (a)  by  way  of   telegraphic   transfer   the  balance  of  the
                    consideration   referred   to   Clause  3  (or  its   Dollar
                    Equivalent)  after  payment of those  monies  referred to in
                    Clause 5.4.2 to 5.4.4 (inclusive).

               (b)  a duly executed print of the CABG Supply Agreement;

               (c)  a duly executed print of the Business Name Licence;

               (d)  a duly executed print of the Chronoflex Supply Agreement;

               (e)  a duly executed print of the Chronoflex Licence

               (f)  a duly executed print of the Deed of Assignment;

               (g)  a duly executed print of the CABG Option Agreement;

               (h)  a duly executed print of the Freemedic Assignment; and

               (i)  a duly executed print of the Deed of Indemnity.

          5.4.2. the Purchaser  shall advance to the Company the sum of $130,459
               (or its  Sterling  Equivalent)  in  satisfaction  of the Vendor's
               liability to the Trade  Creditors  such sum being part payment of
               the consideration referred to in Clause 3;

          5.4.3. the  Purchaser  shall pay the sum of $700,000  or its  Sterling
               Equivalent  to such  account and in such manner as is referred to
               in  Clause  6  below,   such  sum  being  part   payment  of  the
               consideration referred to in Clause 3; and.

          5.4.4. the Purchaser  shall pay the sum of $2,053,713 plus any accrued
               but  unaccounted  for  interest  directly to  Dresdner  Kleinwort
               Benson,  to such  account and in such  manner as they  reasonably
               require,  such  sums  being  the  balance  of  the  consideration
               referred to in Clause 3 .

     5.5. The Purchaser  may in its absolute  discretion  waive any  requirement
          contained  in clauses 5.1 to 5.3, and shall not be obliged to complete
          the  purchase  of any of the  Shares  unless the  purchase  of all the
          Shares is completed in accordance with this Agreement, but may instead
          rescind this  agreement  without  prejudice to any other remedy it may
          have.

     5.6. On or as soon as  reasonably  practicable  following  Completion,  the
          Purchaser shall deliver to the Vendor duly executed Deeds of Variation
          in  respect  of  the  Parent  Company  Guarantees,  and  pending  such
          execution the Purchaser  shall  indemnify and hold harmless the Vendor
          from and against any liability, claims, damages, awards and reasonable
          costs  properly  incurred by or made against the Vendor  directly as a
          result of any calls made pursuant to such Parent Company Guarantees.

6.   RETENTION

     6.1. In accordance with Clause 5.4.3 above, upon Completion,  the Purchaser
          shall pay the  Sterling  Equivalent  of the sum of  US$700,000  into a
          designated  deposit  account in joint names of the Vendor's  Solicitor
          and  the  Purchaser's  Solicitors,  such  funds  to be  dealt  with in
          accordance with this Clause 6.


<PAGE>
     6.2. Subject as provided herein, the Purchaser may apply all or part of the
          retention referred to above in recouping any amount lawfully due to it
          under or by  reason  of any  claim  either  pursuant  to those  Part I
          Warranties  contained in paragraph 4 thereof, or those obligations and
          warranties contained in the Deed of Assignment,  any amount so applied
          shall pro tanto satisfy the liability concerned.

     6.3. Any interest  earned on the retention shall accrue to and form part of
          the retention  and shall be available to satisfy any such claims,  and
          such  interest  (net  of  any  tax  required  by  law  to be  deducted
          therefrom)  shall  accordingly  belong to the  Vendor  subject  to the
          provisions of this Agreement.

     6.4. In the event that the Purchaser  shall not have notified the Vendor in
          writing  of any  claim  referred  to in Clause  6.2  above and  issued
          proceedings  in  respect  thereof  within  18  months   following  the
          Completion Date, the retention shall be released to the Vendor. If the
          Purchaser  shall  have so  notified  any such claim the Vendor and the
          Purchaser  shall  -agree the amount  claimed or in the  absence of any
          agreement shall be referred by either of them to the President for the
          time being of the  Institute of Chartered  Accountants  in England and
          Wales  who shall act as expert  not as  arbitrator  and whose  opinion
          shall be binding on the parties  and any balance  shall be so released
          on that date.  Upon final  determination  of the total amount (if any)
          falling  to be  applied  by the  Purchaser  under  this  Clause 6, any
          balance of the retention shall be released to the Vendor provided that
          no amount shall be released before the expiry of such 18 month period.

     6.5. Any sums paid out from the  retention  to satisfy a liability  arising
          pursuant  to Clause 6.2 shall only be made either upon an order of any
          court of  competent  jurisdiction  or pursuant  to a consent  order or
          other written agreement between the parties.

7.   WARRANTIES AND UNDERTAKINGS

     7.1. The Vendor hereby warrants and undertakes to the Purchaser that:

          7.1.1. the  Vendor  has and will at  Completion  have  full  power and
               authority to enter into and perform this Agreement;

          7.1.2. The  Shares  will at  Completion  constitute  the  whole of the
               issued and allotted share capital of the Company;

          7.1.3. there is and at  Completion  will be no  pledge,  lien or other
               encumbrance  on, over or affecting the Shares and there is and at
               Completion  will be no agreement or arrangement to give or create
               any such  encumbrance  and no claim  has been or will be made any
               person to be entitled to any of the foregoing;

          7.1.4. the Vendor  will be  entitled  to  transfer  the full legal and
               beneficial  ownership of the Shares to the Purchaser on the terms
               of this Agreement;


<PAGE>
          7.1.5. save - as clearly and -fairly set out in the Disclosure Letter,
               the Part II Warranties and those set out in paragraphs 6 to 23 of
               the  Part I  Warranties  are true and  accurate  in all  material
               respects at the date of this  Agreement,  and will continue to be
               so up to and including the Completion Date;

          7.1.6. the  Purchaser  shall not be  entitled  to claim that any fact,
               matter or  circumstance  causes any of the Part II  Warranties or
               those  Warranties  in paragraphs 6 to 23 of Part I to be breached
               if and to the extent that such fact,  matter or circumstance  has
               been  properly  disclosed  to the  Purchaser in  accordance  with
               Clause 7.1.5 above,  save in the case of any fraud or  dishonesty
               on the part of the Vendor or its agents or advisers.

          7.1.7. For  the  avoidance  of  doubt,  those  Warranties  set  out in
               paragraph 1 to 5 (inclusive of Part I of Schedule 2) are true and
               accurate in all respects at the date of this  Agreement  and will
               continue to be so up to and including the Completion Date.

     7.2. The Vendor  undertakes in relation to any Warranty which refers to the
          knowledge,  information belief or awareness of the Vendor, that it has
          made all reasonable  enquiry into the subject matter of that Warranty,
          and that  where  reference  is made to actual  knowledge  no  specific
          enquiry into the subject matter of that Warranty has been made.

     7.3. Each of the Warranties is without prejudice to any other Warranty and,
          except where expressly stated  otherwise,  no clause contained in this
          agreement shall govern or limit the extent or application of any other
          clause.

     7.4. The  Vendor  undertakes  with  the  Purchaser  that it  will  promptly
          disclose in writing to the Purchaser any event or circumstance,  which
          becomes  known to it after  the date of this  Agreement  and  prior to
          Completion,  which is  inconsistent  with any of the Warranties or the
          contents  of the  Disclosure  Letter or which  might be material to be
          known by a purchaser for value of the Shares.

     7.5.

          7.5.1. The  rights and  remedies  of the  Purchaser  in respect of any
               breach of the Warranties shall not be affected by Completion,  by
               any investigation made by it or on its behalf into the affairs of
               the  Company,  by its  rescinding,  or failing  to  rescind  this
               Agreement, or failing to exercise or delaying the exercise of any
               right or  remedy  or by any  other  event or  matter  whatsoever,
               except a specific and duly authorised  written waiver or release,
               and no single or partial  exercise  of any right or remedy  shall
               preclude any further or other exercise.


<PAGE>
          7.5.2. The  Purchaser  shall  not be  entitled  to make any  claim for
               breach of Warranty where it has actual knowledge of any matter or
               thing as at the date of this  Agreement  which would give rise to
               any such claim,  provided that the limitations  contained in this
               Clause 7.5.2 shall not apply to any claim made  pursuant to those
               warranties  contained in paragraph 4 of the Part I Warranties  or
               those  obligations  and  warranties  contained  in  the  Deed  of
               Assignment.

     7.6. If following  Completion,  the Purchaser  becomes aware that there has
          been any breach of the Warranties or any other term of this Agreement,
          the  Purchaser  shall not be  entitled  to rescind or  terminate  this
          Agreement for breach of any of the  Warranties or under the provisions
          of the  Misrepresentation Act 1967 or for any other reason whatsoever,
          but shall be entitled to claim  damages or exercise  any other  right,
          power or remedy under this Agreement or as otherwise provided by law.

     7.7. None of the  information  supplied by the Company or its  professional
          advisers  prior to the date of this  Agreement  to the  Vendor  or its
          agents,  representatives or advisers in connection with the Warranties
          and the contents of the Disclosure Letter, or otherwise in relation to
          the business affairs of the Company, shall be deemed a representation,
          warranty or  guarantee  of its  accuracy by the Company to the Vendor,
          and the Vendor  waives any claims  against the Company  which it might
          otherwise have in respect of it.

     7.8. For the  avoidance  of doubt,  neither the  Disclosure  Letter nor any
          matter  revealed  by it  shall  apply  to,  or in any  way  limit  any
          liability of the Vendor  pursuant to paragraphs 1 to 5 (inclusive)  of
          the Part I Warranties.

     7.9. The Vendor agrees to indemnify and keep  indemnified the Purchaser and
          by way of a  separate  indemnity  the  Company  from and  against  all
          losses, liabilities,  costs, charges, expenses, actions,  proceedings,
          claims and demands which it or they may suffer or incur arising out of
          any breach of the Part I Warranties.

     7.10.Whether in its capacity as  shareholder  or through its  appointees to
          the board of directors  thereof,  the Vendor shall exercise its voting
          rights so as to procure so far as it is able,  that the Company  shall
          not at any time prior to Completion  without the prior written consent
          of the Purchaser:

          7.10.1. incur any  expenditure  on  capital  account or enter into any
               commitments so to do;

          7.10.2.  dispose  of or agree to  dispose  of or grant  any  option in
               respect of any part of its assets  except in the ordinary  course
               of trading;

          7.10.3.  borrow any money or make any  payments  out of or drawings on
               its bank accounts other than routine payments;

          7.10.4. enter into any unusual or abnormal contract or commitments or:

               (i)  grant or agree to grant  any lease or third  party  right in
                    respect  of the  Properties  or  either of them or assign or
                    agree to assign or otherwise dispose of the same;

               (ii) make any loan;


<PAGE>
               (iii)enter  into any  leasing,  hire  purchase  or other  finance
                    agreement.

          7.10.5. declare, make or pay any dividend or other distribution to the
               Vendor;

          7.10.6.  grant or issue  or  agree  to grant or issue  any  mortgages,
               charges,  debentures or other  securities  for money or redeem or
               agree to redeem any such  securities or give or agree to give any
               guarantees or indemnities;

          7.10.7. make any change in the terms and  conditions  of employment or
               pension  benefits of any of its  directors or employees or employ
               or terminate  (other than for good cause) the  employment  of any
               person;

          7.10.8.  create  issue or grant any  option in respect of any class of
               share or loan capital or agree to do so; or

          7.10.9. in any  other  way  depart  from the  ordinary  course  of its
               respective day to day business either as regards the nature scope
               or the manner of conducting the same; and

     7.11.The Vendor shall not at any time prior to Completion without the prior
          written consent of the Purchaser:-

          7.11.1. dispose or purport to dispose of any interest in the Shares or
               any of them or grant  any  option  over or  mortgage,  charge  or
               otherwise encumber the Shares or any of them;

          7.11.2. permit the Company to pass any resolution in general meeting:

          7.11.3. raise any management or other charge against the Company

     7.12. Pending Completion the Vendor shall procure that:-

          7.12.1. the  Purchaser its agents and  representatives  are given full
               access to Cambrian  House and to the books,  records and Business
               Information of the Company upon  reasonable  notice during normal
               business hours:

          7.12.2. the Purchaser is furnished with weekly cash returns and profit
               and  loss  accounts  and such  other  information  regarding  the
               business  and  affairs  of  the  Company  as  the  Purchaser  may
               reasonably require;

          7.12.3.  the  Purchaser  is  furnished  with  a list  of all  proposed
               payments  together  with a copy  of the  invoice  to  which  each
               payment relates prior to payment being made;

          7.12.4. no  cheque  payments  are  made and no new  standing  order or
               direct debit payments are entered into by the Company without the
               prior  written  approval  of the  Purchaser  which  shall  not be
               unreasonably  withheld or delayed  where payment is in accordance
               with the Company's normal credit terms;

          7.12.5. the  Company  maintains  in force all the  insurance  policies
               referred to in the Disclosure Letter.


<PAGE>
     7.13.In  accordance  with Clause 14, the rights or benefits of or under the
          Warranties  and the covenants in Clause 7.1 may be assigned  (together
          with any cause of action  arising in  connection  with any Warranty or
          covenant) by the Purchaser to its successors in title or any purchaser
          from the Purchaser or to any Subsidiary or Holding Company or a fellow
          Subsidiary of the same Holding Company of the Purchaser.

     7.14.If in  respect  of or in  connection  with  any  breach  of any of the
          Warranties any amount  payable to the Purchaser  and/or the Company by
          the Vendor is subject to Taxation,  such additional  amounts should be
          paid to the Purchaser and/or the Company by the Vendor so as to ensure
          that the net amount  received by the  Purchaser  and/or the Company is
          equal to the full amount  payable to the Purchaser  and/or the Company
          under this Agreement.


8.   PROVISION OF BUSINESS INFORMATION

During  the  period  2  years  after  Completion:

     8.1. if any  Business  Information  required for the Business is not in the
          possession of the Purchaser or the Company or is readily  discoverable
          by the Purchaser or the Company,  but is in the possession of or under
          the control of or available to the Vendor, the Vendor shall procure so
          far as  reasonably  practicable  that  such  Business  Information  is
          provided to the Purchaser promptly on request; and

     8.2. if any books or  records of the Vendor  contain  Business  Information
          required for the Business the Vendor shall procure that copies of such
          books or records are given to the Purchaser promptly on request.


9.   RESTRICTIVE COVENANTS

     9.1. For the purpose of assuring to the  Purchaser  the full benefit of the
          businesses and goodwill of the Company,  the Vendor  undertakes by way
          of further  consideration  for the  obligations of the Purchaser under
          this Agreement as separate and independent agreements that it will not
          directly or  indirectly  without  the  Purchasers  consent,  not to be
          unreasonably withheld or delayed:

          9.1.1. at any time after Completion  disclose to any person, or itself
               use for any purpose, and shall use its best endeavours to prevent
               the publication or disclosure of, any Business  Information which
               may, or may have, come to its knowledge;

          9.1.2. for a period  of 3 years  after  Completion  either  on its own
               account or for any other person  directly or indirectly  solicit,
               interfere  with or  endeavour  to entice away from the Company or
               provide in  competition  with the  Company any service or product
               involving or in connection with the Business to any person who to
               its  knowledge is now or has during the 12 months  preceding  the
               date of this  Agreement  been a client or customer , or is or has
               been in the habit of dealing with, the Company;

          9.1.3. for a  period  of 3 years  after  Completion,  either  alone or
               jointly with or as manager,  agent for or employee of any person,
               directly or  indirectly  carry on or be engaged or  concerned  or
               interested in the Business within the Territory.


<PAGE>
          9.1.4. for a period of 12 months after  Completion,  solicit or entice
               away from the  employment  of the  Company  any  person  who is a
               senior employee, consultant to or officer of the Company; or

          9.1.5. knowingly  assist any other  person to do any of the  foregoing
               things.


     9.2. Each  undertaking  contained  in this Clause 9 shall be construed as a
          separate undertaking and if one or more of the undertakings is held to
          be  against  the  public  interest  or  unlawful  or  in  any  way  an
          unreasonable  restraint of trade,  the  remaining  undertakings  shall
          continue to bind the Vendor.

     9.3. The  restrictions  contained in this Agreement shall be in addition to
          and not in  substitution  for any other  restrictions  upon the Vendor
          contained in the Ancillary Document, provided that in the event of any
          conflict between the provisions of this Clause 9 and the terms of such
          Ancillary  Document  the  provisions  of the  latter  documents  shall
          prevail,  and provided  further that the restrictions in this Clause 9
          shall not apply to  matters  done by the  Vendor in  carrying  out its
          obligations  or  exercising  its  rights  pursuant  to such  Ancillary
          Documents


10.  VENDOR'S PROTECTION

     10.1.The Vendor and the Purchaser  agree that the  provisions of Schedule 4
          shall apply in respect of the Part II Warranties.

     10.2.The Vendor and the Purchaser  further agree that Clauses  1,2,3,  4, 5
          and 6 of  Schedule  4  (but  for  the  avoidance  of  doubt  no  other
          provisions  of that  Schedule)  shall  apply in  respect of the Part I
          Warranties.


11.  ANNOUNCEMENTS

     11.1.Subject  to Clause  11.2 no  announcement  concerning  the sale of the
          Shares or any ancillary matter shall be made by the Vendor without the
          prior  written  approval of the  Purchaser,  such  approval  not to be
          unreasonably withheld or delayed.

     11.2.Each party may make an announcement  concerning the sale of the Shares
          or any ancillary matter if required by:-

          (i)  the law of any relevant jurisdiction; or

          (ii) any securities  exchanged or regulatory or  governmental  body to
               which  either  party is subject or  submits,  wherever  situated,
               including (without  limitation) the London Stock Exchange (or its
               successor   or  assign),   SEC  or  AMEX,   whether  or  not  the
               requirements has the force of law

          PROVIDED  THAT  any  such  announcement   shall  be  made  only  after
          consultation with the other parties.


<PAGE>
     11.3.The  restrictions  contained  in this clause  shall  continue to apply
          after the Completion of the sale and purchase of the Shares under this
          Agreement without limit in time.


12.  EFFECT OF COMPLETION

Any  provision of this  Agreement and other  document  referred to in it and any
     matter  contemplated  thereby which is capable of being performed after but
     which has not been performed at or before Completion and all Warranties and
     covenants and other  undertakings  contained in or entered into pursuant to
     this  Agreement  shall  remain  in full  force and  effect  notwithstanding
     completion.


13.  REMEDIES AND WAIVERS

     13.1.No delay or omission on the part of either party to this  Agreement in
          existing  any  right,  power or remedy  provided  by law or under this
          Agreement or any other documents referred to in it shall:-

          (i)  impair such right, power or remedy; or

          (ii) operate as a waiver thereof;

     13.2.The single or partial exercise of any right,  power or remedy provided
          by law or under this agreement shall not preclude any other or further
          exercise thereof or the exercise of any other right, power or remedy.

     13.3.The  rights,  powers  and  remedies  provided  in this  agreement  are
          cumulative  and not  exclusive  of any  rights,  powers  and  remedies
          provided by law.


14.  ASSIGNMENT

     14.1.All or any part of the rights or benefits  of or under this  Agreement
          and  any  Ancillary   Documents,   including  without  limitation  the
          Warranties, may be assigned (together with any cause of action arising
          in  connection  with any of them) by the  Purchaser to a Subsidiary or
          Holding Company,  or a fellow  Subsidiary of the same Holding Company,
          of the Purchaser, but are otherwise non assignable.

     14.2. Obligations under this Agreement shall not be assignable.


15.  FURTHER ASSURANCE

The  Vendor shall from time to time at its own cost, on being  required to do so
     by the  Purchaser,  do or procure the doing of all such acts and/or  things
     within its power  including the  execution of all such  documents in a form
     satisfactory  to the  Purchaser as are  necessary for giving full effect to
     this  agreement  and  securing  to the  Purchaser  the full  benefit of the
     rights, powers and remedies conferred upon the Purchaser in this agreement.


<PAGE>
16.  ENTIRE AGREEMENT

     16.1.For the purpose of this Clause,  "Pre-contractual  Statement"  means a
          draft,  agreement,  undertaking,  representation,  warranty,  promise,
          assurance or arrangement of any nature  whatsoever,  whether or not in
          writing,  relating to the Share Purchase  Documents or any of them (as
          defined in Clause  16.2  below) made or given by a party to any of the
          Share  Purchase  Documents  or any other  person at any time  prior to
          execution of the Share Purchase Documents.

     16.2.This  Agreement,  and the  Ancillary  Documents  (together  the "Share
          Purchase  Documents")  constitute the whole and only agreement between
          the parties relating to the sale and purchase of the Shares.

     16.3.Except to the extent repeated in any of the Share Purchase  Documents,
          the  Share  Purchase  Documents  supersede  and  extinguish  any prior
          Pre-Contractual Statement relating thereto.

     16.4.Each of the  parties  acknowledges  that in  entering  into the  Share
          Purchase Documents or any of them on the terms set out therein,  it is
          not relying upon any Pre-contractual  Statement which is not expressly
          set out therein.

     16.5.No party  shall have any right of action  against  any other  party to
          any of the Share  Purchase  Documents  arising out of or in connection
          with any Pre-Contractual Statement (except in the case of fraud).

     16.6. This Agreement may only be varied in writing signed by each party.


17.  NOTICES

     17.1.A notice  or other  communication  under or in  connection  with  this
          Agreement  shall be in writing and shall be  delivered by hand or sent
          by first class post, pre-paid recorded delivery (or by airmail if sent
          to an address outside the United Kingdom) or by facsimile to the party
          due to receive the notice or communication,  at its address set out in
          this  Agreement  or at such other  address  specified by that party by
          prior written notice to the other.

     17.2.In the  absence  of  evidence  of earlier  receipt,  a notice or other
          communication is deemed given:-

          (i)  if  delivered  by hand,  at the time of  actual  delivery  to the
               address referred to in this Agreement;

          (ii) if sent by mail except  airmail,  two Business Days after posting
               it;

          (iii) if sent by airmail, ten Business Days after posting it; and

          (iv) if sent by facsimile, on production of a transmission report from
               the  machine  which  sent  the  facsimile   indicating  that  the
               facsimile was sent in its entirety to the facsimile number of the
               recipient.


<PAGE>
     17.3.The Vendor  agrees  that for the  purposes of this  Agreement,  or any
          Ancillary  Documents,  any  notice  to be made or given to the  Vendor
          shall be  deemed  to have  been  validly  made or given if sent to the
          Vendor's  Solicitors  notwithstanding  any  failure  to send  any such
          notice to the  Vendor  or the  non-receipt  of any such  notice by the
          Vendor.


18.  CONFIDENTIALITY

     18.1.Subject to Clause 18.2 each party shall treat as strictly confidential
          all  information  received or obtained as a result of entering into or
          performing this agreement which relates to:-

          (i)  the provisions of this Agreement;

          (ii) the negotiations relating to this Agreement; or

          (iii) the other party

     18.2.A party may disclose information which would otherwise be confidential
          if and to the extent such disclosure is:-

          (i)  required by the law of any relevant jurisdiction;

          (ii) required by any securities exchange or regulatory or governmental
               body to which any party is subject or submits, wherever situated,
               including (without  limitation) the London Stock Exchange (or its
               successor  or  assign)  the  SEC  or  AMEX  whether  or  not  the
               requirement for information has the force of law;

          (iii)required  to vest  the  full  benefit  of this  Agreement  in any
               party;

          (iv) disclosed to the professional  advisers,  auditors and bankers of
               such party;

          (v)  of  information  which has  already  come into the public  domain
               through no fault of that party; or

          (vi) approved by all the other  parties  having  given  prior  written
               approval to the disclosure,  such approval not to be unreasonably
               withheld or delayed.

     PROVIDED THAT any such  information  disclosed  pursuant to paragraphs 18.1
          and 18.2 shall be  disclosed  only after  consultation  with the other
          party.


19.  COSTS AND EXPENSES

Each of the parties  shall pay its own costs and  expenses  (including,  but not
     limited to, the fees of all external legal advisers and their out-of-pocket
     expenses)  in  relation to the  negotiations  leading up to the sale of the
     Shares and to the  preparation,  execution and carrying into effect of this
     agreement and all other documents referred to in it and the Vendor confirms
     that no expense of whatever  nature  relating to the sale of the Shares has
     been borne or is payable by the Company.


20.  COUNTERPARTS

     20.1.This Agreement may be executed in any number of  counterparts,  and by
          the parties on separate counterparts, but shall not be effective until
          each party has executed at least one counterpart.


<PAGE>
     20.2.Each counterpart  shall constitute an original of this agreement,  but
          all the  counterparts  shall together  constitute but one and the same
          instrument.


21.  INVALIDITY

If   at any time any provision of this agreement is or becomes illegal,  invalid
     or  unenforceable  in any respect under the law of any  jurisdiction,  that
     shall not affect or impair:-

     (i)  the legality,  validity or  enforceability in that jurisdiction of any
          other provision of this agreement; or

     (ii) the legality,  validity or  enforceability  under the law of any other
          jurisdiction of that or any other provision of this agreement.


22.  CHOICE OF GOVERING LAW

This agreement  shall be governed by and  construed in  accordance  with English
     law.

23.  JURISDICTION

The  parties to this agreement  irrevocably agree that the courts of England are
     to have  non-exclusive  jurisdiction to settle any disputes which may arise
     out of or in  connection  with  this  agreement  and that  accordingly  any
     Proceedings may be brought in such courts. Nothing contained in this Clause
     shall limit the right of the Purchaser or the Vendor to take proceedings in
     any  other  court of  competent  jurisdiction,  nor  shall  the  taking  of
     proceedings in one or more jurisdictions preclude the taking of proceedings
     in any other  jurisdiction,  whether  concurrently  or not,  to the  extent
     permitted by the law of such other jurisdiction.

IN  WITNESS  WHEREOF the parties hereto have executed this Agreement the day and
year  first  before  written.


<PAGE>
SIGNED  by  or  on  behalf  of
CARDIOTECH
INTERNATIONAL  INC
in  the  presence  of:-
Signature
Witness
Address
Full  Name
Occupation
Title


SIGNED  by  or  on  behalf  of
NERVATION  LIMITED
 in  the  presence  of:-
Signature
Witness
Address
Full  Name
Occupation
Title


<PAGE>
                                   SCHEDULE 1
                                   ----------
                             DETAILS OF THE COMPANY
                             ----------------------

NAME  :                      CARDIOTECH  INTERNATIONAL  LIMITED
-------                      ----------------------------------

REGISTERED  NO.  :           3198267
------------------           -------

REGISTERED  OFFICE  :        5/7  GROSVENOR  COURT
---------------------        ---------------------
                             FOREGATE  STREET
                             ----------------
                             CHESTER
                             -------
                             CH1  1HG
                             --------

DIRECTORS  :                 ALAN  EDWARDS
------------                 -------------
                             MICHAEL  SZYCHER
                             ----------------
                             MICHAEL  ADAMS
                             --------------

SECRETARY  :                 IAN  VICARY
------------                 -----------

AUTHORISED SHARE CAPITAL :   [  1,671,759]
------------------------------------------


ISSUED  SHARE  CAPITAL  :    [  1,671,759  ORDINARY  SHARES  OF  1.00  EACH]
----------------------------------------------------------------------------


SHAREHOLDERS                 [ CARDIOTECH  INTERNATIONAL  INC.]
---------------------------------------------------------------


<PAGE>
                                   SCHEDULE 2
                                   ----------

                                  (WARRANTIES)
                                  ------------

                                PART I WARRANTIES
                                -----------------

1.   OWNERSHIP OF THE SHARES

The  Vendor  is  thesole  legal  and  beneficial  owner  of  the  Shares.

2.   CAPACITY OF THE VENDOR
     ---------------

The  Vendor  has the requisite power and authority to enter into and perform its
obligations  under  this  Agreement.

3.   PROPERTY
     -------

The  Company is under no liability  whether  actual or  contingent in respect of
     Tarvin Sands and whether arising  directly or indirectly as a result of the
     occupation  of that  property  by the  Company,  the Vendor or by any other
     party.

4.   INTELLECTUAL  PROPERTY
     ----------------------

     4.1. The Vendor is legally and beneficially entitled to the Retained Rights
          and has full right  title and  authority  to perform  its  obligations
          whether under this Agreement or the Ancillary  Documents to the extent
          that those obligations relate to the Retained Rights.

     4.2. The use by the Vendor of the Retained Rights in the performance of its
          obligations  pursuant to this  Agreement and the  Ancillary  Documents
          does not infringe the Intellectual Property rights of any third party.

     4.3. The  rights to  Chronoflex  RC are  wholly  owned by the  Vendor,  are
          confidential  and  proprietary  in nature and  constitute  a valid and
          enforceable trade secret.

     4.4. The  Intellectual  Property Rights are all of the rights necessary for
          the Company to carry on the Business.

     4.5. The Vendor is neither the legal owner nor licensee of any Intellectual
          Property   rights  and  will  not  assert   against  the  Company  any
          Intellectual  Property rights,  other than the Retained Rights,  which
          will or could affect the Company's ability to carry on the Business.

     4.6. The  Existing  Rights  are a  definitive  list of of all rights in any
          Intellectual  Property (other than copyright and unregistered designs)
          owned by the Company.

     4.7. Details of all licences granted to or by the Company in respect of any
Intellectual  Property  are  scheduled  to  the  Disclosure  Letter.

     4.8. All rights in all Intellectual Property and Business Information owned
          or otherwise required for the Business are beneficially  owned, vested
          in or validly  granted or licensed by third parties to the Company and
          are  not  subject  to any  limit  as to  time  or any  other  material
          limitation,  right of termination (including,  without limitation,  on
          any change in the  underlying  ownership or control of the Company) or
          restriction  and all renewal fees and steps required by the Company to
          be paid or taken for their  maintenance  or protection  have been paid
          and taken.


<PAGE>
     4.9. All rights in Intellectual Property and all Business Information owned
          or otherwise  required for the  Business is in the  possession  of the
          Company and the Company is not a party to any confidentiality or other
          agreement  or subject to any duty  (other than any  statutory  duties)
          which  restricts  the free use or  disclosure  of any of that Business
          Information.

     4.10.Except  as set  out in the  Disclosure  Letter,  the  Company  has not
          granted any licence or permitted any  sub-licence nor is it obliged to
          grant any licence, consent for sub-licence or assignment in respect of
          any Intellectual Property owned or otherwise required for the Business
          nor  has  it   disclosed  or  is  obliged  to  disclose  any  Business
          Information  required for the  Business to any person,  other than its
          employees  for  the  purpose  of  carrying  on  its  business  or  its
          professional advisers.

     4.11.The  Company  is  not  in  breach  of  any  licence,   sub-licence  or
          assignment  to  which  it is a party in  respect  of any  Intellectual
          Property  owned or required  for the  Business or of any  agreement to
          which the Company is a party under which any Business  Information was
          or is to be made available to it.

     4.12.The Company  has not at any time during the past four years,  received
          notice of any unauthorised use or infringement by any person of any of
          the Intellectual  Property or Confidential  Business Information owned
          or otherwise required for the Business.

     4.13.So far  as  the  Vendor  is  aware  the  Company's  records,  systems,
          controls,  data or information are not recorded,  stored,  maintained,
          operated or  otherwise  wholly or partly  dependent  on or held by any
          means  (including any electronic,  mechanical or photographic  process
          whether  computerised  or not)  which  (including  all means of access
          thereto  and  therefrom)  are not under the  exclusive  ownership  and
          direct control of the Company.

     4.14.So far as the Vendor is aware the  Company  has,  if required to do so
          under the Data Protection Act 1998, duly registered as a data user and
          has complied  with the data  protection  principles as set out in that
          Act.

     4.15.So far  as  the  Vendor  is  aware  all  computer  hardware,  software
          networks or other information  technology used by or required to carry
          on the Business and fulfil its existing  contracts and  commitments is
          either owned by or validly leased or licensed to the Company

5.   PRE 1996 ACCOUNTS AND TAX
In   respect of the period prior to March 1996,  the Vendor hereby repeats those
     Warranties  set  out  in  paragraphs  6 to  23  (inclusive)  below  mutatis
     mutandis, provided that where any reference is made to the knowledge of the
     Vendor  (whether  actual or not)  such  knowledge  limitation  shall not be
     deemed to apply to those pre March 1996 warranties referred to herein.

6.   THE ACCOUNTS AND TAX

So  far  as  Vendor  is  aware:
-----------

     6.1. Save for  Taxation on the profits of the Company  attributable  to the
          period after the Last Accounts  Date,  the Company has no liability in
          respect of Taxation (whether actual or contingent) and, in particular,
          has no outstanding liability for:-

          6.1.1.  Taxation  in any part of the world  assessable  or  payable by
               reference  to profits,  gains,  income or  distributions  earned,
               received  or paid or arising or deemed to arise on or at any time
               prior to the  Last  Accounts  Date or in  respect  of any  period
               starting before the Last Accounts Date; or


<PAGE>
          6.1.2. for  purchase,  value added,  sales or other similar tax in any
               part of the world referable to transactions effected on or before
               the Last Accounts Date that is not  disclosed,  noted or provided
               for in the Last Accounts.

     6.2. The amount of the  provision  for deferred  Taxation in respect of the
          Company contained in the Last Accounts was, at the Last Accounts Date,
          in accordance with  accountancy  practices  generally  accepted in the
          United  Kingdom  and  commonly   adopted  by  companies   carrying  on
          businesses  similar  to  those  carried  on by  the  Company  and,  in
          particular,  was in accordance  with SSAP 15 (or any replacement of it
          instituted by the Accounting Standard Board).

     6.3. If all facts and  circumstances  which are now known to the Company or
          the Vendor had been known at the time the Last Accounts were drawn up,
          the  provision  for deferred  Taxation  that would be contained in the
          Last  Accounts  would be no  greater  than the  provision  which is so
          contained.

7.   TAX EVENTS SINCE THE LAST ACCOUNTS DATE

So  far  as  the  Vendor  is  aware,  since  the  Last  Accounts  Date:-

     7.1. the Company has not declared, made or paid any distribution within the
          meaning of ICTA 1988;

     7.2. no accounting reference period of the Company has ended;

     7.3. there has been no  disposal  by the  Company  of any asset  (including
          trading  stock) or supply of any service or  business  facility of any
          kind (including a loan of money or the letting, hiring or licensing of
          any property whether  tangible or intangible) in  circumstances  where
          the consideration actually received or receivable for such disposal or
          supply was less than the  consideration  which could be deemed to have
          been received for tax purposes;

     7.4. no disposal  by the  Company  has taken place or other event  occurred
          which  will or may have the effect of  crystallising  a  liability  to
          Taxation which should have been included in the provision for deferred
          Taxation  contained  in the Last  Accounts  if such  disposal or other
          event had been planned or predicted at the Last Accounts Date;

     7.5. the Company has not made any payment or  incurred  any  obligation  to
          make a payment  which  will not be  deductible  in  computing  trading
          profits for the purposes of  corporation  tax, or be  deductible  as a
          management expense of an investment company;

     7.6. the Company has not been a party to any  transaction for which any tax
          clearance  provided for by statute could have been obtained where such
          a tax clearance has not been obtained;

     7.7. the  Company  has not paid or  become  liable to pay any  interest  or
          penalty in connection  with any tax, has otherwise  paid any tax after
          its due date for  payment or owes any tax the due date for  payment of
          which has passed;

     7.8. no event has occurred  which will give rise to a tax  liability on the
          Company  calculated  by  reference  to deemed  (as  opposed to actual)
          income,  profits or gains or which will result in the Company becoming
          liable to pay or bear a tax liability directly or primarily chargeable
          against or attributable to another person, firm or company.


<PAGE>
8.   TAX RETURNS, DISPUTES, RECORDS AND CLAIMS.

So  far  as  the  Vendor  is  aware:

     8.1. The Company  has made or caused to be made all returns  required to be
          made,  and has  supplied  or caused  to be  supplied  all  information
          required to be  supplied,  to any revenue  authority,  including  (but
          without limitation) the Inland Revenue and the Customs & Excise;

     8.2. There  is  no  dispute  or   disagreement   outstanding   nor  is  any
          contemplated at the date of this Agreement with any revenue  authority
          regarding  liability  or  potential  liability  to  any  tax  or  duty
          (including in each case  penalties or interest)  recoverable  from the
          Company or regarding the  availability  of any relief from tax or duty
          to the  Company  and there are no  circumstances  which make it likely
          that any such dispute or disagreement will commence;

     8.3. The Company has sufficient records relating to past events,  including
          any  elections  made,  to calculate  the tax liability or relief which
          would arise on any disposal or on the  realisation  of any asset owned
          at the Last  Accounts  Date by the  Company or acquired by the Company
          since that date but before Completion;

     8.4. The Company has submitted all claims and disclaimers or withdrawals of
          claims  which have been  assumed to have been made for the purposes of
          the Last Accounts;

     8.5. The Company has not made any  election to waive  exemption in relation
          to any land in accordance with paragraph 2 of Schedule 10 VATA 1994;

     8.6. The amount of tax  chargeable  on the  Company  during any  accounting
          period since the incorporation of the Company has not, to any material
          extent,  depended  upon any  concession,  agreement or other formal or
          informal  arrangement  with  any  revenue  authority,  including  (but
          without limitation) the Inland Revenue or the Customs and Excise.

9.   STAMP DUTY AND STAMP DUTY RESERVE TAX

     9.1. All  documents  which  cannot  be  relied  upon all or  certain  legal
          proceedings or which are not eligible for registration  unless stamped
          and which are in the  possession  of the Company or by virtue of which
          the Company has any right have been duly stamped;

     9.2. Since  the  Last  Accounts  Date  the  Company  has not  incurred  any
          liability to stamp duty reserve tax.

10.  VALUE ADDED TAX

     10.1.The Company is  registered  for the purpose of VATA 1994 and has made,
          given,  obtained  and kept  full,  complete,  correct  and  up-to-date
          returns, records, invoices and other documents appropriate or required
          for those  purposes and is not in arrears with any payments or returns
          due and has not been required by the Commission of Customs & Excise to
          give security under paragraph 4 of Schedule 11 VATA 1994.

     10.2.The  Company  has never  been  treated  as a member  of a group  under
          section  43 VATA  1994 and no  application  has ever been made for the
          Company to be so treated.

     10.3.The Company has not within the two years  ending on the Last  Accounts
          Date been in default in respect of any prescribed accounting period as
          mentioned in section 59 or section 59A VATA 1994.

     10.4.Full  details  of any claim for bad debt  relief  made by the  Company
          under  section  36 VATA 1994 have been  disclosed  in  writing  to the
          Purchaser in the Disclosure Letter.

     10.5.The Company has not made any  election to waive  exemption in relation
          to any land in accordance with paragraph 2 of Schedule 10 VATA 1994.


<PAGE>
     10.6.The  Disclosure  Letter  contains  full  details  of any assets of the
          Company to which the provisions of Part XV Value Added Tax Regulations
          1995 (the Capital Goods Scheme) apply and in particular:-

          10.6.1. the identity (including in the case of leasehold property, the
               term of years), date of acquisition and cost of the asset; and

          10.6.2. the  proportion of input tax for which credit has been claimed
               (either  provisionally  or  finally  in a tax  year  and  stating
               which).

11.  DUTIES

So   far as the Vendor is aware,  to the extent that such  payments are due from
     the  Company,  all value added tax,  import duty and other taxes or charges
     payable  to H.M.  Customs & Excise  upon the  importation  of goods and all
     excise  duties  payable  to H.M.  Customs & Excise in respect of any assets
     (including trading stock) imported,  owned or used by the Company have been
     paid in full.

12.  TAX ON DISPOSAL OF ASSETS

So   far as the Vendor is aware,  on a disposal of all its assets by the Company
     for:-

     12.1.in the case of each asset  owned by the  Company at the Last  Accounts
          Date, a consideration  equal to the value  attributed to that asset in
          preparing the Last Accounts; or

     12.2.in the case of each asset  acquired  since the Last  Accounts  Date, a
          consideration  equal to the  consideration  given for the  acquisition
          then either:-

          12.2.1.  in  respect  of any  asset  falling  within  (i)  above,  the
               liability  to tax (if any) which would be incurred by the Company
               in respect of that asset  would not exceed the amount  taken into
               account  in  respect  of that  asset  in  computing  the  maximum
               liability to deferred Taxation as stated in the Last Accounts; or

          12.2.2. in respect of any asset  within (ii) above,  no tax  liability
               would be incurred by the Company in respect of that asset.

13.  REPLACEMENT OF BUSINESS ASSETS

So   far as the Vendor is aware,  full  particulars  of each claim under section
     115 or 116 CGTA  1979 or under  sections  152 or 153 of the TCGA  1992 made
     prior  to the date of this  Agreement  to which  section  117 CGTA  1979 or
     section 154 TCGA 1992  applies and which  affects any asset which was owned
     by the Company on or after the Last  Accounts  Date (except  where the held
     over gain is treated as having  accrued  prior to the Last  Accounts  Date)
     have been disclosed in writing to the Purchaser in the Disclosure Letter.

14.  DISTRIBUTIONS

     14.1.Since its  incorporation,  the Company has not made any  repayment  of
          share capital to which Section  210(1) ICTA 1988 applies or issued any
          share  capital  or other  security  as paid up  otherwise  than by the
          receipt of new consideration within the meaning of Part VI ICTA 1988;

     14.2.No part of the amount  payable on  redemption  of any share capital or
          security of the  Company  will be a  distribution,  as defined in ICTA
          1988.


<PAGE>
15.  CLOSE COMPANY

     15.1.So far as the Vendor is aware, the Company has requested its Inspector
          of Taxes to proceed  under  paragraph  16 of  Schedule 19 ICTA 1988 in
          relation to every accounting  period ended within six years before the
          date of this  Agreement,  and to  which  this  paragraph  applies,  no
          apportionment  in  respect  of any such  period can now be made and no
          such  apportionment will become possible otherwise than in consequence
          of the  cessation  of any  trade or  business  after  the date of this
          agreement;

     15.2.The  Company  has no  outstanding  loan to  which  the  provisions  of
          section 419 ICTA 1988 would apply (loans to participators etc);

     15.3.The Company is not a close  investment  holding  company as defined in
          section 13A ICTA 1988.

16.  NON DEDUCTIBLE REVENUE OUTGOINGS

So   far as the Vendor is aware, the Company is not under any obligation to make
     any future payment which will be prevented (whether on the grounds of being
     a  distribution,  or for  any  other  reason)  from  being  deductible  for
     corporation  tax purposes,  whether as a deduction in computing the profits
     of a trade or as an expense of  management or as a charge on income or as a
     non-trading  debit under  Chapter II Part IV Finance Act 1996, by reason of
     any statutory provision, other than section 74(f) ICTA 1988 (capital)

17.  DEDUCTIONS AND WITHHOLDINGS

So   far as the Vendor is aware, The Company has made all deductions in respect,
     or on account,  of any tax from any payments made by it which it is obliged
     or entitled to make and has accounted in full to the appropriate  authority
     for all amounts so deducted.

18.  RESIDENCE

So   far as the Vendor is aware,  the United  Kingdom is the only country  whose
     tax  authorities  seek to charge tax on the world-wide  profits or gains of
     the Company  and the Company has never paid tax on income  profits or gains
     to any tax authority in any other country except the United Kingdom.

19.  DEMERGER

So   far as the Vendor is aware, the Company has not been concerned in an exempt
     distribution (as defined in section 214( 4) ICT A 1988)

20.  NON-ARM'S LENGTH TRANSACTIONS

So   far as the Vendor is aware,  the Company is not a party to any  transaction
     or  arrangement  under which it may be required to pay for any asset or any
     services  or  facilities  of any kind an  amount  which is in excess of the
     market  value of that asset or services or  facilities  or will receive any
     payment for an asset or any services or  facilities of any kind that it has
     supplied or  provided or is liable to supply or provide  which is less than
     the market value of that asset, services or facilities.

21.  INTRA-GROUP TRANSACTIONS

So   far as the  Vendor is aware,  the  Company  has not,  at any time since its
     incorporation,  acquired any asset from any other company which was, at the
     time of the  acquisition,  a member of the same group of  companies as that
     member for the purposes of any tax.

22.  ASSOCIATED COMPANIES

So   far as the  Vendor is aware,  neither  the Vendor nor any person or persons
     connected  with it has  control of an  associated  company  of the  Company
     within the meaning of section 13 ICTA 1988.


<PAGE>
23.  INHERITANCE TAX

So   far as the Vendor is aware:

     23.1.There is no Inland  Revenue  charge as defined  in section  237 of the
          Inheritance  Tax Act 1984  outstanding  in respect of any asset of the
          Company or in respect of the Shares.

     23.2.There are not in any  existence  any  circumstances  whereby the power
          mentioned  in  section  212(1)  Inheritance  Tax  Act  1984  could  be
          exercised  in  relation to any assets of the Company or in relation to
          the Shares.


<PAGE>
                               PART II WARRANTIES
                               ------------------


1.   CAPACITY OF THE VENDOR


     2.1  The  execution and delivery of, and the  performance  by the Vendor of
          its obligations under this Agreement and the Ancillary Documents, will
          not:-


          (i)  result  in a breach  of,  or  constitute  a  default  under,  any
               instrument  to which the  Vendor or the  Company is a party or by
               which the Vendor or the Company is bound;

          (ii) result in a breach of any order,  judgment or decree of any court
               or  governmental  agency to which the Vendor or the  Company is a
               party or by which the Vendor or the Company is bound; or

          (iii)require the consent of the  shareholders of the Company or of any
               other persons.

2.   ARRANGEMENTS BETWEEN THE COMPANY AND THE VENDOR

          No indebtedness  (actual or contingent) and no contract or arrangement
          is outstanding between the Company and the Vendor.

3.        OTHER INTERESTS OF VENDOR

          Save for the business  carried on by the Vendor as contemplated by any
     of the  Agreed  Form  documents,  the  Vendor  has no  interest,  direct or
     indirect,  in any business  which  competes with the Business or intends to
     acquire any such interest. No person connected with the Vendor has any such
     interest  or, so far as the Vendor is aware,  intends  to acquire  any such
     interest.

4.   GROUP STRUCTURE, ETC.

     4.1  The Shares comprise the whole of the issued and allotted share capital
          of the  Company and all of them are fully paid up or credited as fully
          paid up.

     4.2  There is no agreement or commitment outstanding to which the Vendor is
          a party  which  calls  for the  allotment,  issue or  transfer  of, or
          affords to any person the right to call for the allotment or issue of,
          any shares  (including  the Shares) or  debentures in or securities of
          the Company.

     4.3  So far as the Vendor is  actually  aware the  Company  does not act or
          carry on business  in  partnership  with any other  person nor is it a
          member  of  any  corporate  or  unincorporated  body,  undertaking  or
          association  nor holds or is liable on any share or security  which is
          not fully paid up or which carries any liability.

     4.4  So far as the Vendor is actually  aware the Company  does not have any
          branch.,  agency, place of business or permanent establishment outside
          the United Kingdom.


<PAGE>
5.   OPTIONS, MORTGAGES AND OTHER ENCUMBRANCES

          There is no option, right to acquire,  mortgage,  charge, pledge, lien
          or other  form of  security  or  encumbrance  or  equity  on,  over or
          affecting  the Shares and there is no agreement or  commitment to give
   or create any and no claim has been made by any person to be entitled to any.



6.   ACCURACY AND ADEQUACY OF INFORMATION

     6.1  The  information  given  in  Schedule  1 is true and  accurate  in all
          respects.

     6.2  The copy of the  memorandum and articles of association of the Company
          is contained in the Disclosure Bundle.



7.   ACCOUNTS

     7.1  The Accounts:.

          (i)  were prepared in accordance  with the provisions of the Companies
               Acts and accountancy  principles generally accepted in the United
               Kingdom  at the  Last  Accounts  Date  and  commonly  adopted  by
               companies  carrying on businesses  similar to those carried on by
               the Company;

          (ii) make  provision  reasonably  regarded  as  adequate  for  bad and
               doubtful debts and make proper  provision for Taxation on profits
               (whether of an income or capital  nature)  relating to any period
               ending on or before the date to which they are made up;

          (iii)showed a true and fair view of the assets and  liabilities of the
               Company at the Last Accounts Date; and

          (iii) are not affected by any unusual or non-recurring items.

     7.2  So far as the Vendor is aware at the Last  Accounts  Date the  Company
          had  no  outstanding   capital  commitment  which  is  not  adequately
          disclosed or provided for in the last Accounts;

     7.3  So far as the Vendor is aware the  accounting  records of the  Company
          have  been kept on a proper  and  consistent  basis (no  change in the
          methods or bases of valuation  or  accountancy  treatment  having been
          made since  incorporation),  are  up-to-date  and  contain all matters
          required by the Companies Acts to be entered in them.

     7.4  So far as the Vendor is aware the  Management  Accounts  were prepared
          after  due and  careful  enquiry  in  accordance  with the  accounting
          principles  generally  accepted in the United  Kingdom and  accurately
          represent  the state of affairs and profits or losses of the  Business
          as at the Management Accounts Date.


<PAGE>
8.   EVENTS SINCE THE LAST ACCOUNTS DATE

     8.1  Since the Last  Accounts Date so far as the Vendor is aware:- (i) save
          for the losses  incurred in the ordinary  course of trading  there has
          been no material  adverse change in the financial or trading  position
          of the Company;

          (ii) the  business of the Company has been  carried on in the ordinary
               and  usual  course  and no  unusual  or unduly  onerous  contract
               differing from the routine  contracts  necessitated by the nature
               of its trade has been entered into by the Company;

          (iii)no asset of a value in excess  of 7500 has and no assets  with an
               aggregate  value in  excess  of  15,000  have  been  acquired  or
               disposed of on capital  account or has been agreed to be acquired
               or disposed of

          (iv) no debts or other  receivables  of the Company have been factored
               or sold or agreed to be sold;

          (v)  no resolution  of the Company in general  meeting has been passed
               other than resolutions relating to the routine business of annual
               general meetings;

          (vi) no change in the accounting  reference  period of the Company has
               been made; and



     8.2  So far as the  Vendor  is  aware  all  book  debts  shown  in the Last
          Accounts  have been  realised for an aggregate sum not being less than
          that shown in the Last Accounts.

9.   CONTRACTS AND COMMITMENTS

     9.1  So far as the Vendor is  actually  aware the  Company is not under any
          obligation, nor is it a party to any contract, which cannot readily be
          fulfilled  or  performed  by it on time and  without  undue or unusual
          expenditure of money or effort.

     9.2  So far as the Vendor is  actually  aware the Company is not a party to
          nor has any  liability  (present  or future)  under any  guarantee  or
          indemnity or letter of credit or any leasing,  hiring,  hire purchase,
          credit sale or  conditional  sale  agreement  or has entered  into any
          contract or commitments involving,  or likely to involve,  obligations
          or expenditure of an unusual or exceptional nature or magnitude.

     9.3  So far as the Vendor is  actually  aware the Company is not a party to
          any contract or  arrangement  which  restricts its freedom to carry on
          the Business, or any agency, distribution or management agreement.

     9.4  So far as the Vendor is  actually  aware  neither  the Company nor the
          Vendor is aware of any breach of, or any  invalidity,  or grounds  for
          determination,  rescission,  avoidance or repudiation of, any contract
          to which the Company is a party or of any allegation of such a thing,

     9.5  So far as the Vendor is actually  aware the Company has no outstanding
          bid or tender or sale or  service  proposal  which is  substantial  in
          relation to its Business.

     9.6  So far as the Vendor is actually  aware  except for any  guarantee  or
          warranty implied by law or contained in its standard terms of business
          (a copy of which is attached to the Disclosure Letter) the Company has
          not given any  guarantee,  indemnity,  warranty  or made any  material
          representation,  in respect of services  supplied or  contracted to be
          supplied by it or accepted  any  liability  or  obligation  that would
          apply after any such services had been supplied by it.


<PAGE>
     9.7  So far as the Vendor is  actually  aware the Company is not a party to
          any joint  venture  agreement  or  arrangements  or any  agreement  or
          arrangements  under which it is to  participate  with any other in any
          business.

     9.8  So far as the Vendor is  actually  aware the Company is not a party to
          any agreement or arrangement or under any obligation under which it is
          or may become  liable to make any  investment  (as  defined in section
          1(1) of the Financial Services Act 1986) with, or to deposit any money
          with,  or to provide  any loan or  financial  accommodation  or credit
          (other  than normal  trade  credit) to any  person,  or to  subscribe,
          convert, acquire, dispose of or underwrite any investment.

     9.9  So far as the Vendor is  actually  aware the Company is not a party to
          any contract which falls within any of the cases specified below:-

          (i)  the contract relates to matters not within the ordinary  business
               of the Company;

          (ii) the contract is of one year or greater duration; or

          (iii)the  contract  can be  terminated  by reason of any change in the
               underlying  ownership  or  control of the  Company,  and for this
               purpose  "contract"  includes any  understanding,  arrangement or
               commitment however described.


10.  INSIDER CONTRACTS

     So   far as the Vendor is aware:-

     (i)  there is not, and there has not at any time since  incorporation been,
          any contract or  arrangement  to which the Company is, or was, a party
          and in which the  Vendor,  or any  director  of the Company is, or has
          been, interested, either directly or indirectly; and

     (ii) the  Company  is not a party to,  nor have its  profits  or  financial
          position  during  that  period  been  affected  by,  any  contract  or
          arrangement which is not of an arm's length nature.

11.  POWERS OF ATTORNEY

     So far as the  Vendor  is aware  the  Company  has not  given  any power of
     attorney or other authority which is still  outstanding or effective to any
     person to enter into any contract or commitment on its behalf other than to
     its employees or directors to enter into routine  trading  contracts in the
     normal course of their duties.

12.  GRANTS AND ALLOWANCES

     So far as the Vendor is aware the  Company  has not applied for or received
     any grant,  allowance,  aid or subsidy from any supranational,  national or
     local authority or government agency during the last six years.

13.  SUPPLY OF SERVICES

     No client of the  Company  has during the 12 months  preceding  the date of
     this  Agreement ,  indicated to the Vendor an intention to cease to use the
     services of the Company.


<PAGE>
14.  LICENCES

14.1 In  respect of  products  supplied  by the Vendor to the  Company or on its
     behalf,  the  Vendor  has  obtained  all  necessary   licences,   consents,
     permissions or approvals required of the Vendor by law.

14.2 So far as the Vendor is aware the Company has obtained and  maintained  all
     other licences,  consents or other permissions or approvals required for or
     in connection  with the carrying on of the business now being carried on by
     the  Company  and,  the  Vendor  is not  aware of any  which  circumstances
     indicate that any licence, consent, permission or approval required for the
     carrying  on of the  Business is likely to be revoked or which may confer a
     right of revocation.

15.  BANK ACCOUNTS AND BORROWINGS

     15.1 The Vendor is not aware of any bank accounts maintained or used by the
          Company other than those set out in the Disclosure Letter by reference
          to the name and  address  of the bank and the number and nature of the
          account.

     15.2 So far as the Vendor is aware the  Company  does not have  outstanding
          any loan  capital and has not incurred or agreed to incur on behalf of
          the  Company  any  borrowing  which  the  Company  has not  repaid  or
          satisfied,  nor has the  Vendor on behalf  of the  Company  it lent or
          agreed to lend any money  which has not been repaid to it nor owns the
          benefit of any debt  present or future  (excluding  debts due to it in
          the  normal  course  of  trading)  nor is it a  party  to or  has  any
          obligation under:

          (i)  any loan agreement,  debenture,  acceptance credit facility, bill
               of exchange,  promissory note,  finance lease.  debt or inventory
               financing, discounting or factoring arrangement or sale and lease
               back arrangement; or

          (ii) any other  arrangement  the purpose of which is to raise money or
               provide finance or credit.

     15.3 So far as the Vendor is actually  aware, No event which is an event of
          default  under or any breach of any of the terms of any loan  capital,
          borrowing,  debenture  or  financial  facility of the Company or would
          entitle any third party to call for repayment prior to normal maturity
          has occurred or, been alleged.

     15.4 So far as the Vendor is aware the Company has not granted any security
          over its assets,  whether to its bankers or  otherwise  and whether by
          way of charge, debenture or any other instrument.


16.  INSOLVENCY

     16.1 So far as the Vendor is aware no order has been made and no resolution
          has been passed for the winding up of the Company or for a provisional
          liquidator  to be  appointed in respect of the Company and no petition
          has been presented and no meeting has been convened for the purpose of
          winding up the Company.

     16.2 No  administration  order has been made and, no  petition  for such an
          order has been presented in respect of the Company.

     16.3 No  receiver  (which   expression  shall  include  an   administrative
          receiver)  has been  appointed in respect of the Company or all or any
          of its assets.


<PAGE>
     16.4 No voluntary  arrangement has been proposed under section 1 Insolvency
          Act 1986 in respect of the Company.

     16.5 So far as the Vendor is aware no unsatisfied judgment,  order or award
          is outstanding against the Company.

     16.6 No  application  has been made in respect of the Vendor for an interim
          order under section 253 Insolvency Act 1986.

     16.7 No interim  receiver has been  appointed of the property of the Vendor
          under section 286 Insolvency Act 1986.

     16.8 No  person  has been  appointed  by the  court to  prepare a report in
          respect of the Vendor under section 273 Insolvency Act 1986.

     16.9 No event  analogous to any of the foregoing has occurred in or outside
          England.

     16.10 No guarantee or loan capital, of the Company is overdue for payment.

17.  LITIGATION

     So far as the Vendor is aware the Company is not engaged in any litigation,
     mediation or arbitration,  administrative or criminal proceedings,  whether
     as claimant,  defendant or otherwise,  and so far as the Vendor is aware no
     litigation,   mediation   or   arbitration,   administrative   or  criminal
     proceedings  by or against the Company is pending,  threatened  or expected
     and, so far as the Vendor is aware there is no fact or circumstance  likely
     to  give  rise  to  any  such   litigation,   mediation   or   arbitration,
     administrative  or criminal  proceedings or to any proceedings  against any
     director or employee (past or present) of the Company in respect of any act
     or default for which the Company might be vicariously liable.

18.  OWNERSHIP  AND  CONDITION  OF  ASSETS

     18.1 Save for assets supplied on normal retention of the terms, each of the
          assets included in the Last Accounts or acquired by the Company (other
          than current assets sold,  realised or applied in the normal course of
          trading or  business) is owned both  legally and  beneficially  by the
          Company  free from any third  party  rights  and each of those  assets
          capable of possession is in the possession of the Company.

     18.2 Save for assets  supplied  on normal  retention  of title  terms,  the
          Company  has not agreed so far as the  Vendor is aware to acquire  any
          asset  on terms  that the  property  in it does  not pass  until  full
          payment is made.


19.  PROPERTY

     19.1 Cambrian  House is the only  property  owned,  used or occupied by the
          Company or in respect of which the Company  has any estate,  interest,
          right or  liability  at the date  hereof.  Cambrian  House is used and
          occupied for the purpose of the Business.


     19.2 So far as the Vendor is aware all necessary  permissions  and consents
          in  respect  of use for the  purpose  referred  to  above  and for any
          development  at Cambrian House have been obtained and all such use and
          development   has  been  carried  out  in  accordance  with  any  such
          permissions and consents and with applicable planning legislation.


<PAGE>
     19.3 So far as the  Vendor  is aware  there  are no  outstanding  disputes,
          actions,  claims,  demands or complaints in respect of Cambrian  House
          nor does the Vendor expect any.

     19.4 So far as the Vendor is aware no notice  affecting  Cambrian House has
          been given or received by the Vendor.

     19.5 The Company has not at any time:-

          (i)  had vested in it (whether as original tenant or undertenant or as
               an assignee or transferee or otherwise) any freehold or leasehold
               property other than Cambrian House, nor

          (ii) given any covenant or entered into any  agreement,  deed or other
               document  (whether as a tenant or  undertenant or as an assignee,
               transferee, guarantor or otherwise) in respect of any freehold or
               leasehold property other than those disclosed to the Purchaser in
               the Disclosure Letter.


20.  COMPETITION AND TRADE REGULATION LAW

     20.1 So far as the Vendor is aware,  the  Company is not and has not been a
          party to or is or has been  concerned in any agreement or  arrangement
          or is  conducting  or has  conducted  itself  (whether  by omission or
     otherwise) in any manner which:-

          (i)  has been registered under the RTPA 1976;

          (ii) contravenes  the  provisions of the Resale Prices Act 1976 or any
               secondary legislation adopted under the Fair Trading Act 1973;

          (iii)is  registrable,  unenforceable  or void  (whether in whole or in
               part) or renders it liable to civil,  criminal or  administrative
               proceedings by virtue of ally  anti-trust or similar  legislation
               in any  jurisdiction  in which the  Company  intends  to carry on
               business or where its activities may have an effect; or

          (iv) is likely to infringe the  provisions  of Chapter l or Chapter II
               of the Competition Act 1998.

     20.2 So far as the Vendor is aware, the Company has not been a party to nor
          has it been  concerned in any agreement or  arrangement  in respect of
          which any  undertaking has been given by or any order made against the
          Company  pursuant  to  the  RTPA  1976  or  in  respect  of  which  an
     undertaking  has been given by or an order made  against  the  Company
     pursuant to the Resale Prices Act 1976.


<PAGE>
21.  EMPLOYMENT

     21.1 Neither the Vendor nor its appointees to the board of directors of the
          Company  have   received  any  notices,   engaged  any   employees  or
          consultants  nor have  they  agreed  any  variations  relating  to the
          contracts  of  employment  of any employee  of, or the  contracts  for
          service of any consultant to the Company.


<PAGE>
                                   SCHEDULE 3
                                   ----------
                          SHORT PARTICULARS OF PROPERTY
                          -----------------------------
                                     PART I
                                     ------
                                  TARVIN SANDS
                                  ------------
                         TARVIN SANDS INDUSTRIAL ESTATE
                         ------------------------------
                                   BARROW LANE
                                   -----------
                                     TARVIN
                                     ------
                                   NR CHESTER
                                   ----------
                                     CH3 8JF
                                     -------

                                     PART II
                                     -------
                                 CAMBRIAN HOUSE
                                 --------------
                                  HARWOOD ROAD
                                  ------------
                                     BRYMBO
                                     ------
                                     WREXHAM
                                     -------
                                    LL11 5EA
                                    --------


<PAGE>
                                   SCHEDULE 4
                                   ----------


LIMITATION ON CLAIMS UNDER THE PART II WARRANTIES (AND WHERE SPECIFIED, THE PART
                                  I WARRANTIES)

1.     NO  CLAIM  FOR  MATTERS  DISCLOSED  OR  DONE  AT  PURCHASER'S  REQUEST
       ----------------------------------------------------------------------

The  Purchaser  shall not be  entitled  to claim  against  the Vendor  under the
     Warranties  in  respect  of any  matter  or  thing  after  the date of this
     Agreement done or omitted to be done at the written  request of or with the
     prior written approval of the Purchaser

2.     TIME  LIMIT  ON  CLAIMS
       -----------------------

No  claim  shall  be  brought  by  the  Purchaser  for  any breach of any of the
Warranties:



     2.1. unless  in the case of the Part II  Warranties  it  shall  have  given
          notice in writing of such claim  specifying in  reasonably  sufficient
          detail the nature of the breach and so far as  practicable  the amount
          claimed  the Vendor  not later  than 18 months  after the date of this
          Agreement;

     2.2. unless  in  the  case  of  those  Part  I  Warranties  numbers  1 to 4
          (inclusive)  and any warranties in the Ancillary  Documents,  it shall
          have given notice in writing of such claim  specifying  in  reasonably
          sufficient  detail the nature of the breach and so far as  practicable
          the amount  claimed the Vendor not later than 36 months after the date
          of this Agreement;

     2.3. unless  in the case of those  Part I  Warranties  numbered  5 to 23 it
          shall  have  given  notice in  writing  of such  claim  specifying  in
          reasonably  sufficient  detail  the nature of the breach and so far as
          practicable the amount claimed the Vendor not later than 7 years after
          the date of this Agreement;

     2.4. where  notice in  writing  of such claim  shall  have been  given,  if
          proceedings in respect of such claim containing full particulars shall
          not have been  issued and served on the Vendor  within 4 months  after
          the date of such notice being received.

3.   MINIMUM CLAIM

The  Vendor  shall  only be  liable  in  respect  of any  claim  brought  by the
     Purchaser for breach of any of the  Warranties  including any warranties in
     the Ancillary Documents.:

     3.1. if the amount of the claim (or all such related claims) exceeds 2000

     3.2. if the amount of the  claim,  when  aggregated  with the amount of all
          claims for which the Vendor is liable  under  this  Agreement  exceeds
          25,000 and in the event that any such claims  exceed 25,000 the Vendor
          shall be liable  for the full  amount of the  claims  and not just the
          excess over 25,000.



4.   MAXIMUM CLAIM

     4.1. The  liability  of the  Vendor in  respect  of claims  brought  by the
          Purchaser for breaches of the  Warranties  (including  any  warranties
          contained  in the  Ancillary  Documents)  shall not  exceed the sum of
          $7,000,000 or the Sterling Equivalent.


<PAGE>
5.   NO DOUBLE CLAIM

The  Vendor  shall not be liable  for any breach of any  Warranty  if and to the
     extent  that  the loss  occasioned  by such  breach  of  warranty  has been
     recovered  pursuant to a claim brought under any other warranties  (whether
     contained  in the  Ancillary  Documents  or  otherwise)  and vice versa the
     warranties contained in the other Agreed Form documents and vice versa.

6.   REIMBURSEMENT OF SUMS RECOVERED FROM THIRD PARTIES

If   the Vendor pays at any time to the Purchaser an amount  pursuant to a claim
     under the Warranties and either before or after such payment is made by the
     Vendor the Purchaser  recovers from a third party any sum in respect of any
     matter  giving rise to such  Warranty  claim,  then  subject  always to the
     Purchaser's  right to set off such  amount  against  any other  unsatisfied
     Warranty claim,  the Purchaser shall forthwith  either reduce the amount of
     the  relevant  claim  payable by the Vendor or pay to the Vendor so much of
     the amount paid to the Purchaser as does not exceed the sum recovered  from
     such  third  party as the  case  may be,  and in each  such  case  less the
     reasonable  costs,  charges  and  expenses  incurred  by the  Purchaser  in
     recovering that sum from such third party.

7.   SPECIFIC LIMITATIONS

The  Purchaser  shall not  be  entitled  to  claim  for  breach  of  the Part II
     Warranties if and to the extent that:

     7.1. the claim would not have arisen but for any act, omission, transaction
          or  arrangement  (or  any  combination  of  any of  the  same)  of the
          Purchaser  or any  subsidiary  of the  Purchaser or the Company or any
          successor  in  title to the  Shares  or  their  respective  directors,
          employees or agents after  Completion  otherwise  than in the ordinary
          course of business,  including any change in the accounting  policy or
          practice of the Company having effect after Completion;

     7.2. the claim arises or is increased as a result of the passing of, or any
          change  in or any  change in the  interpretation  of,  any law,  rule,
          regulation or  administrative  practice of any government,  government
          department, local or state agency, authority regulatory or fiscal body
          after the date of this Agreement and having retrospective effect;

8.   SET OFF

     8.1. The liability of the Vendor shall be reduced if and to the extent that
          provision is made in the Last  Accounts for the  circumstances  giving
          rise to such liability.

9.   DEEMED REDUCTION OF PURCHASE PRICE

The  amount of any  successful  claim against the Vendor under this Agreement or
     pursuant to any  warranties  contained  in the  Ancillary  Documents  shall
     constitute or be deemed to constitute a reduction in the price paid for the
     Shares,  and  under  any of the  Ancillary  Documents  shall be  deemed  to
     constitute a reduction in the relevant consideration thereunder.

10.  RETENTION OF RECORDS

The  Purchaser  will procure that the Company will retain and preserve all books
     records  documents  and  information  (including  information  recorded  or
     retained  in any  electronic  form) of or  relating  to the Company and its
     business which are or may be relevant in connection  with any claim brought
     by the Purchaser  against the Vendor under this  Agreement] for three years
     after the Last Accounts Date.


<PAGE>
     10.1.The  Purchaser  shall  inform the Vendor in writing of any event which
          comes to the  notice of the  Purchaser  whereby  it  appears  that the
          Vendor is or is likely to become  liable  for a claim  under a Part II
          Warranty as soon as reasonably  practicable  after the date upon which
          such event comes to the notice of the Purchaser. Subject always to the
          indemnity  referred to below,  the Purchaser  shall (and shall procure
          that the  Company  shall)  take such  reasonable  action and give such
          assistance  in  connection  with any claim under a Part II Warranty as
          the Vendor may reasonably request in writing to avoid dispute, resist,
          litigate,   compromise,   defend  or  appeal   against  any  claim  or
          adjudication  in respect  thereof at the  request of the  Vendor.  The
          conduct of any proceedings of whatsoever  nature arising in connection
          with any such claim shall be  delegated  entirely to the Vendor and in
          that  connection the Purchaser  shall give or cause to be given to the
          Vendor such  assistance as it may reasonably  require in disputing any
          such claim.  The Vendor hereby fully and  effectively  indemnifies the
          Purchaser and as a separate indemnity the Company from and against all
          reasonable  costs and expenses and liabilities  incurred by or awarded
          against them in compliance with their obligations under this clause.

     10.2.The  Purchaser  shall not make any  admission or compromise in respect
          of any claim  under a Part II  Warranty  save  with the prior  written
          consent of the Vendor (such consent not to be unreasonably withheld or
          delayed).

     10.3.If any  claim  under a Part  II  Warranty  arises  by  reason  of some
          liability which at the time the Vendor is notified shall be contingent
          only,  then the  Vendor  shall  not be under  any  obligation  to make
          payment to the Purchaser or the company  thereunder until such time as
          such contingent  liability  ceases to be so contingent,  provided that
          the time limits set out in Clause 2 above shall only begin to run from
          the date such contingent liability ceases to be so contingent.

     10.4.The Purchaser  shall in respect of any and all claims under Part II of
          the  Warranties  be under a duty to the Vendor to mitigate its loss in
          accordance with normal common law principals.


<PAGE>
                                   SCHEDULE 5
                                   ----------
                          INTELLECTUAL PROPERTY RIGHTS
                          ----------------------------
                                     PART 1
                                     ------
                                 RETAINED RIGHTS
                                 ---------------


PATENT NO.    COUNTRY    ISSUE DATE                 TITLE
-----------  ----------  ----------  -----------------------------------

5549860      USA         27.08.1996  Method of forming a vascular
                                     prosthesis (CABG)
EP0495869B1  EU& German  03.01.1996  Polymer products (CABG)
             National
5,863,627    USA         26.01.1999  Hydrolytically and Proteolytically
                                     [stable] silicon co-polymers
5,254662     USA         19.10.1993  Biostable Polyurethene Products


NATURE                         TITLE
Proprietary  Trade  Secret     Chronoflex  AR  family  of  solution  based
                               polycarbonate  urethanes

<TABLE>
<CAPTION>
                                               Part 2
                                               ------
                                         Transferred Rights
                                         ------------------


[PATENT NO.  COUNTRY            ISSUE DATE      TITLE
<S>          <C>                <C>             <C>

63-78318     Japan                 01.02. 1993  Arterial Prosthesis (vascular graft -
                                                process patent)
0286220B1    EU includes           31.03. 1993  Methods and apparatus for making
             Austria,                           polymer materials (vascular graft -
             Belgium,                           process patent)
             Denmark,
             France,
             Germany, Great
             Britain, Ireland,
             Italy, Japan,
             Luxembourg,
             Netherlands,
             Portugal, Spain,
             Sweden,
             Switzerland]


<PAGE>
5132066      USA                    21.07.1992  Method of forming a bio
                                                compatible vascular prosthesis
                                                (vascular graft - process patent)
5756035      USA                    31.04.1993  Method of making an access graft
                                                and a vascular prosthesis
6,117,535    USA                    26.05.1998  Bio compatible devices (process for
                                                fibre covering)
EP0807425A1  EU including           12.09.2000  Making an access graft
             [Austria,
             Belgium,
             Denmark,
             France,
             Germany, Great
             Britain, Ireland,
             Italy, Japan,
             Luxembourg,
             Netherlands,
             Portugal, Spain,
             Sweden,
             Switzerland]

TRADE MARK  COUNTRY  REGISTERED NO.  SPECIFICATION  RENEWAL DATE
----------  -------  --------------  -------------  ------------
Myolink
VascuLink
</TABLE>



All  unregistered  rights  anywhere  in  the  world  relating  to the trademarks
Vasculink  and  Myolink.

The  results  of  all  pre-clinical and clinical trials relating to the vascular
access  graft  produced  by the Company under the name Vasculink, the peripheral
bypass  graft  developed  by the Company under the name Myolink and the coronary
bypass graft developed by the Company under the name Cardiopass ("the Products")
together  with  any  copyright  relating  to  such  results.

Any and all copyright and design right in design document for the Products.  Any
and  all  design  rights  relating  to  the  Products.


<PAGE>
                                     Part 3
                                     ------
                                 Existing Rights
                                 ---------------

Implied  licence  to  use  Chronoflex  in  respect  of  the  Business.



<PAGE>
                                   SCHEDULE 6
                                   ----------
                            PARENT COMPANY GUARANTEES
                            -------------------------

GUARANTEED  PARTY                     NATURE  OF  OBLIGATION
-----------------                     ----------------------

Black  Arrow  Finance                 Guarantee  of  Company's  obligations
Polybiomed                            Guarantee of obligations of Company
                                      to Polybiomed Limited - share options


OPTIONS  GRANTED  TO  SIGNING DISTRIBUTION   ACHIEVEMENT OF   TERMINATION  OF
--------------------  --------------------   --------------   ---------------
                      AGREEMENT              SALES            AGREEMENT DUE TO
                      ---------              -----            ----------------
                                                              STRATEGIC ALLIANCE
                                                              ------------------
                                                              BY  CTI
                                                              -------
[  *  ]




*CERTAIN INFORMATION ON THIS PAGE HAS BEEN OMITTED AND FILED SEPARATELY WITH THE
COMMISSION.  CONFIDENTIAL  TREATMENT  HAS  BEEN  REQUESTED  WITH  RESPECT TO THE
OMITTED  PORTIONS.


<PAGE>
                                   SCHEDULE 7
                                   ----------
                                 Trade Creditors

[  *  ]





*CERTAIN INFORMATION ON THIS PAGE HAS BEEN OMITTED AND FILED SEPARATELY WITH THE
COMMISSION.  CONFIDENTIAL  TREATMENT  HAS  BEEN  REQUESTED  WITH  RESPECT TO THE
OMITTED  PORTIONS.


<PAGE>


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