EP MEDSYSTEMS INC
S-3/A, 1998-05-18
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
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14

   As filed with the Securities and Exchange Commission on May 15, 1998
                                                            
                                             Registration No. 333-51301

             SECURITIES AND EXCHANGE COMMISSION
                   Washington, D.C. 20549
                              
                     AMENDMENT NO. 1 TO
                          FORM S-3
                   REGISTRATION STATEMENT
                            UNDER
                 THE SECURITIES ACT OF 1933
                              
                     EP MedSystems, Inc.
   (Exact name of registrant as specified in its charter)
                              
New Jersey               5047           22-3212190
- ----------          ------------        ----------------
(State of           (Primary SIC        (I.R.S. Employer
incorporation       Code Number)        Identification
                                        Number)

                      100 Stierli Court
                  Mount Arlington, NJ 07856
                       (973) 398-2800
(Address and telephone number of registrant's principal executive offices)

          James J. Caruso, Chief Financial Officer
                     EP MedSystems, Inc.
                      100 Stierli Court
                  Mount Arlington, NJ 07856
                  Telephone (973) 398-2800
  (Name, address and telephone number of agent for service)

                         Copies to:
                  Dean M. Schwartz, Esquire
            Stradley, Ronon, Stevens & Young, LLP
                  2600 One Commerce Square
                   Philadelphia, PA 19103
                  Telephone (215) 564-8000
      Approximate date of commencement of proposed  sale  to
the  public: From time to time after the effective  date  of
this Registration Statement.

      If  the only securities being registered on this  Form
are   being   offered  pursuant  to  dividend  or   interest
reinvestment plans, please check the following box.  [ ]

      If any of the securities being registered on this Form
are  to be offered on a delayed or continuous basis pursuant
to  Rule  415 under the Securities Act of 1933, as  amended,
other  than  securities  offered  only  in  connection  with
dividend or interest reinvestment plans, check the following
box.  [X]

     If this Form is filed to register additional securities
for an offering pursuant to Rule 462(b) under the Securities
Act,  please check the following box and list the Securities
Act  registration statement number of the earlier  effective
registration statement for the same offering.  [ ]

      If  this  Form  is  a post-effective  amendment  filed
pursuant  to  Rule 462(c) under the Securities  Act,  please
check  the  following  box  and  list  the  Securities   Act
registration  statement  number  of  the  earlier  effective
registration statement for the same offering.  [ ]

      If  delivery of the prospectus is expected to be  made
pursuant to Rule 434, please check the following box.  [ ]

The registrant hereby amends this Registration Statement  on
such  date  or  dates  as  may be  necessary  to  delay  its
effective  date  until the registrant shall file  a  further
amendment  which specifically states that this  Registration
Statement  shall thereafter become effective  in  accordance
with Section 8(a) of the Securities Act of 1933, as amended,
or  until  the Registration Statement shall become effective
on  such  date  as the Commission, acting pursuant  to  said
Section 8(a), may determine.

<PAGE>


                              
             SUBJECT TO COMPLETION, DATED MAY 15, 1998

PROSPECTUS

                     EP MEDSYSTEMS, INC.
              2,250,000 Shares of Common Stock
                              
This Prospectus relates to 2,250,000 shares of common stock,
no par value, stated value $.001 per share ("Common Stock"),
of  EP  MedSystems,  Inc.,  a New  Jersey  corporation  (the
"Company"),  which  may be offered  from  time  to  time  by
certain  security  holders  of  the  Company  (the  "Selling
Security   Holders"),   or   by  their   pledgees,   donees,
transferees or other  successors in interest, to or  through
underwriters  or  directly to other  purchasers  or  through
brokers  or  agents in one or more transactions  at  varying
prices  determined  at  the time of  sale  or  at  fixed  or
negotiated prices.  See "Plan of Distribution."

The  Company will not receive any of the proceeds  from  the
sale  of the 2,250,000 shares of Common Stock (the "Shares")
offered  hereby  by  the  Selling  Security  Holders.    The
expenses  of  the  registration  of  the  Shares  under  the
Securities  Act of 1933, as amended (the "Securities  Act"),
and  the  registration or qualification of the Shares  under
any  applicable state securities laws will be  paid  by  the
Company.   The  aggregate proceeds to the  Selling  Security
Holders will be the offering price of the Shares sold,  less
applicable  agents' commissions and underwriting  discounts,
if any.

All  of  the Shares were "restricted securities"  under  the
Securities  Act prior to their registration hereunder.   The
Company  sold  all  of  the Shares to the  Selling  Security
Holders  in  a  private transaction on April 9,  1998.   The
shares  of  Common Stock sold in such transaction constitute
the Shares being registered hereunder.

The  Common  Stock is traded on the Nasdaq  National  Market
("Nasdaq") under the symbol "EPMD."  On April 28, 1998,  the
last reported sale price of the Common Stock was $2.8125 per
share.

The securities offered hereby involve a high degree of risk.
                     See "Risk Factors."

THESE  SECURITIES HAVE NOT BEEN APPROVED OR  DISAPPROVED  BY
THE   SECURITIES  AND  EXCHANGE  COMMISSION,  OR  ANY  STATE
SECURITIES  COMMISSION NOR HAS THE SECURITIES  AND  EXCHANGE
COMMISSION  OR ANY STATE SECURITIES COMMISSION  PASSED  UPON
THE   ACCURACY   OR   ADEQUACY  OF  THIS   PROSPECTUS.   ANY
REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.

                                                        Proceeds to
                        Underwriting      Proceeds        Selling
            Price to    Discounts and        to          Security
           Public (1)  Commissions (2)  Company (3)     Holders (4)
           ---------   ---------------  -----------     -----------
Per Share   $2.8125          --              --         $2.8125
Total      $6,328,125        --              --         $6,328,125

1. Represents the last reported sale price per  share  of
Common Stock on Nasdaq  on April 28, 1998.
2. Cannot be estimated at this time.
3. The Company will pay estimated expenses of $46,000  in
connection with the offering of the Shares by the  Selling
Security Holders.
4. Before   applicable   underwriting   discounts    or
commissions, which cannot be estimated at this time.

             The date of this Prospectus is May   , 1998

<PAGE>

No  dealer,  salesperson or other person has been authorized
to give any information or to make any representations other
than  those  contained in this Prospectus and, if  given  or
made, such information or representations must not be relied
upon as having been authorized by the Company.  Neither  the
delivery  of  this  Prospectus nor any sale  made  hereunder
shall,  under any circumstances, create any indication  that
there has been no change in the affairs of the Company since
the date hereof or that the information contained herein  is
correct as of any date subsequent to the date hereof.   This
Prospectus  does  not  constitute an  offer  to  sell  or  a
solicitation  of  an  offer to buy  any  securities  offered
hereby by anyone in any jurisdiction in which such offer  or
solicitation is not authorized or in which the person making
such  offer or solicitation is not qualified to do so or  to
anyone  to  whom  it  is  unlawful to  make  such  offer  or
solicitation.
                              

                      TABLE OF CONTENTS
                                                     Page
Available Information                                 1
Incorporation of Certain Documents by Reference       2
Forward Looking Statements                            2
Risk Factors                                          3
The Company                                           3
Use of Proceeds                                       3
Selling Security Holders                              4
Plan of Distribution                                  5
Legal Matters                                         6
Experts                                               6

                    AVAILABLE INFORMATION
                              
The  Company has filed with the U.S. Securities and Exchange
Commission  (the "Commission") a Registration  Statement  on
Form S-3 (the "Registration Statement") under the Securities
Act  with  respect to the Shares of Common Stock offered  by
this  Prospectus.  This Prospectus, filed  as  part  of  the
Registration  Statement,  does  not  contain  all   of   the
information set forth in the Registration Statement and  the
exhibits  and schedules thereto, certain portions  of  which
have  been omitted in accordance with the Commission's rules
and  regulations.  For further information with  respect  to
the Company and the Shares offered hereby, reference is made
to  the  Registration  Statement and  to  the  exhibits  and
schedules   filed   therewith.   The  statements   in   this
Prospectus  are qualified in their entirety by reference  to
the contents of any agreement or other document incorporated
herein  by reference, a copy of which is filed as an exhibit
to either the Registration Statement or other filings by the
Company  with  the  Commission.  A copy of the  Registration
Statement   may   be  inspected  without   charge   at   the
Commission's  principal offices, and copies of  all  or  any
part of the Registration Statement may be obtained from such
office   upon  payment  of  the  fees  prescribed   by   the
Commission.

The Company is subject to the informational requirements  of
the  Securities  Exchange  Act  of  1934,  as  amended  (the
"Exchange Act"), and in accordance therewith, files reports,
proxy  statements and other information with the Commission.
Such  reports, proxy statements and other information  filed
by  the  Company may be inspected and copied (at  prescribed
rates) at the public reference facilities maintained by  the
Commission in Washington, D.C. (450 Fifth Street, N.W., Room
1024,  Judiciary Plaza, Washington, D.C. 20549) and  at  the
Commission's  Regional Offices in New York  (7  World  Trade
Center,  13th Floor, New York, New York 10048)  and  Chicago
(Citicorp  Center,  500  West Madison  Street,  Suite  1400,
Chicago,  Illinois  60661).  The Company  is  an  electronic
filer  and the Commission maintains a web site that contains
reports,   proxy  and  information  statements   and   other
information  regarding registrants that file  electronically
with  the  Commission.   The address  of  the  web  site  is
"http://www.sec.gov."   The   Company's    reports,    proxy
statements  and other information may also be  inspected  at
the  offices  of  the  National  Association  of  Securities
Dealers, Inc., 1735 K Street, N.W., Washington, D.C. 20006.

<PAGE>


       INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE
                              
The  following  documents filed with the Commission  by  the
Company are incorporated by reference into this Prospectus:

(1)  The Company's Annual Report on Form 10-KSB for the year
ended December 31, 1997;

(2)  The Company's Quarterly Report on Form 10-QSB for the
quarter ended March 31, 1998;

(3)  The Company's Current Report on Form 8-K dated April
14, 1998;

(4)  The description of the Common Stock contained in the
Company's Registration Statement on Form 8-A filed April 19,
1996; and

All  documents  filed  with the Commission  by  the  Company
pursuant  to  Section  13(a), 13(c),  14  or  15(d)  of  the
Exchange  Act subsequent to the date of this Prospectus  and
prior to the termination of the offering of the Shares shall
be   deemed  to  be  incorporated  by  reference  into  this
Prospectus and to be a part hereof from the respective dates
of  filing  such  documents.  Any statement contained  in  a
document  incorporated  or  deemed  to  be  incorporated  by
reference  herein  shall be deemed modified,  superseded  or
replaced for purposes of this Prospectus to the extent  that
a  statement  contained herein or in any subsequently  filed
document  that  also is or is deemed to be  incorporated  by
reference  herein  modifies,  supersedes  or  replaces  such
statement.    Any  statement  so  modified,  superseded   or
replaced  shall  not  be  deemed,  except  as  so  modified,
superseded  or  replaced,  to  constitute  a  part  of  this
Prospectus.

The  Company  will provide without charge  to  each  person,
including  any beneficial owner of Common Stock, to  whom  a
copy  of  this  Prospectus is delivered, upon such  person's
written  or  oral  request, a copy of any  and  all  of  the
documents  incorporated  by  reference  herein  (other  than
exhibits  to  such  documents,  unless  such  exhibits   are
specifically incorporated by reference into the  information
that  this  Prospectus incorporates).   Requests  should  be
directed  to  EP MedSystems, Inc. 100 Stierli  Court,  Mount
Arlington,   NJ   07856,  Attention:  Corporate   Secretary,
telephone: (973) 398-2800.

                 FORWARD-LOOKING STATEMENTS
                              
In  addition  to  historical  information,  this  Prospectus
contains forward-looking statements relating to such matters
as   anticipated  financial  and  operational   performance,
business  prospects, technological developments, results  of
clinical  trials,  new  products, research  and  development
activities  and  similar  matters.  The  Private  Securities
Litigation  Reform Act of 1995 provides a  safe  harbor  for
forward-looking  statements.   The  Company  notes  that   a
variety  of factors could cause the Company's actual results
and  experience  to differ materially from  the  anticipated
results  or  other expectations expressed in  the  Company's
forward-looking  statements.  When used in this  Prospectus,
the  words  or phrases "believes," "anticipates," "expects,"
"intends," "will likely result," "estimates," "projects"  or
similar  expressions are intended to identify such  forward-
looking  statements,  but are not  the  exclusive  means  of
identifying    such   statements.    Such    forward-looking
statements  are only predictions, and the actual  events  or
results may differ materially from the results discussed  in
the forward-looking statements.  Factors that could cause or
contribute to such differences include, but are not  limited
to,  those matters discussed herein in the section  entitled
"Risk Factors."

The  Company  cautions  readers  to  review  the  cautionary
statements set forth in this Prospectus and in the Company's
other   reports  filed  with  the  Securities  and  Exchange
Commission and cautions that other factors may prove  to  be
important in affecting the Company's business and results of
operations.   Readers  are  cautioned  not  to  place  undue
reliance  on  these forward-looking statements, which  speak
only  as of the date of this report.  The Company undertakes
no  obligation  to  publicly  revise  these  forward-looking
statements  to  reflect events or circumstances  that  arise
after the date of this report.
                              
<PAGE>


                        RISK FACTORS
                              
An  investment in the Company's Common Stock is  speculative
in nature, involves a high degree of risk and should only be
made  by  an investor who can afford the loss of his  entire
investment. Prospective purchasers should carefully consider
the  risk  factors contained in the section titled  "Factors
That  May Impact Future Operations" in the Company's  Annual
Report on Form 10-KSB and other periodic reports filed under
the Exchange Act, as well as the other information set forth
in  this  Prospectus, before purchasing the  Shares  offered
hereby.  Such risk factors could cause the Company's  actual
results  to  differ materially from those expressed  in  the
Company's  forward-looking statements in this Prospectus  or
have  a material adverse effect upon the Company's business,
results of operations, prospects and financial condition.

                         THE COMPANY

EP  MedSystems, Inc.  designs, manufactures  and  markets  a
broad-based    line   of   products    for    the    cardiac
electrophysiology   ("EP")  market  for   the   purpose   of
diagnosing,  monitoring,  managing  and  treating  irregular
heartbeats known as arrhythmias.  This product line includes
the  EP  WorkMate,  a computerized monitoring  and  analysis
workstation  (the  "EP  WorkMate"),  the  EP-3  computerized
electrophysiology stimulator (the "EP-3 Stimulator" or  "EP-
3")  and  the PaceBase/TeleTrace III receiver, an integrated
ECG  monitoring device and computerized transmission  system
for automation of pacemaker and arrhythmia follow-up testing
and   data  archiving.   The  Company's  product  line  also
includes  diagnostic electrophysiology catheters,  temporary
pacing catheters and related disposable supplies.

The  Company  has also developed a new product for  internal
cardioversion  of  atrial fibrillation known  as  the  ALERT
System (the "ALERT System"), which uses a patented electrode
catheter   to   deliver  measured,  variable,   low   energy
electrical impulses directly to the inside of the  heart  in
order  to  convert  atrial fibrillation to  a  normal  heart
rhythm.   As  of  April  28,  1998,  the  ALERT  System   is
undergoing clinical trials in the United States.

The Company was incorporated in New Jersey in January, 1993.
The  Company's principal offices are located at 100  Stierli
Court,  Mount Arlington, NJ 07856, and its telephone  number
is 973-398-2800.


                       USE OF PROCEEDS
                              
The  Company will not receive any of the proceeds  from  the
sale of the Shares by the Selling Security Holders.  The net
proceeds from the sale of the Shares will be received by the
Selling Security Holders.

<PAGE>


                  SELLING SECURITY HOLDERS
The  following table sets forth information as of April  17,
1998  with respect to each of the Selling Security  Holders,
including their respective names, record holdings of  shares
of  the Company's Common Stock owned before the offering  of
the  Shares,  the  number of shares of  Common  Stock  being
offered for each of their respective accounts and the number
of  shares of Common Stock to be owned of record by each  of
them immediately following the sale of the shares.

                           Shares of      Shares of         Common
                            Common          Common         Stock to
       Name of            Stock Owned    Stock Being       be Owned
   Selling Security         Before         Offered        After the
        Holder             Offering        (1) (2)         Offering
- ----------------------    -----------    -----------      ---------
SC Fundamental Value                                         
Fund, LP (3)                376,800        339,500          37,300
10 East 50th Street                                            
New York, NY 10022                                             
                                                               
SC Fundamental Value                                         
BVI, Ltd. (3)               373,200        335,500          37,700
c/o SC BVI Partners                                            
10 East 50th Street                                            
New York, NY 10022                                             
                                                               
H & Q Life Sciences                                         
Investors (3) (4)           430,000        430,000            0
50 Rowes Wharf                                                 
Boston, MA 02110-6679                                          
                                                               
H & Q Healthcare                                         
Investors (3) (4)           645,000        645,000            0
50 Rowes Wharf                                                 
Boston, MA 02110-6679                                          
                                                               
Special Situations                                         
Fund III LP (3)             411,000        375,000          36,000
153 East 53rd Street                                           
New York, NY 10022                                             
                                                               
Special Situations                                         
Cayman Fund (3)             137,000        125,000          12,000
153 East 53rd Street                                     
New York, NY 10022                                       

(1)   Assumes the sale of all the Shares offered by each  of
the Selling Security Holders.

(2)    On  April  9,  1998,  the  Selling  Security  Holders
purchased  2,250,000 Shares of Common Stock in  a  private
placement of such securities conducted by the Company.  The
aggregate offering proceeds from the sale of the Shares was
$5,062,500, based on a per share price of $2.25. The Company
intends  to use the proceeds of the private placement  for
working capital and general corporate purposes.

(3)   SC Fundamental Value Fund, LP and SC Fundamental Value
BVI,  Ltd.  share  common management.  H&Q  Life  Sciences
Investors  and  H&Q  Healthcare  Investors  share   common
management.  The management companies of Special Situations
Fund III LP and Special Situations Cayman Fund share certain
common ownership.

(4)  H&Q Life Sciences Investors and H&Q Healthcare
Investors are significant shareholders of the Company by
virtue of their holding in the aggregate greater than 10% of
the issued and outstanding common stock.

Except  as  described  above, none of the  Selling  Security
Holders has held any position or office or has had any other
material  relationship  with the  Company,  or  any  of  its
affiliates, within the past three years.

<PAGE>

                    PLAN OF DISTRIBUTION

All  of  the Shares offered hereby may be sold from time  to
time  by the Selling Security Holders, or by their permitted
assigns or permitted transferees.  The sale of the Shares by
the  Selling Security Holders may be effected from  time  to
time in transactions through Nasdaq, or on one or more other
securities  markets and exchanges on which  the  Shares  are
then  listed, in privately negotiated transactions,  through
the  writing  of  options on the Shares,  or  otherwise,  or
through  a  combination of such methods of  sale,  at  fixed
prices  that may be changed, at market prices prevailing  at
the  time  of  sale, at prices relating to  such  prevailing
market prices or at negotiated prices.  In addition, any  of
the  Shares  that  qualify for sale  pursuant  to  Rule  144
promulgated  under  the  Securities  Act  may  be  sold   in
transactions complying with such Rule, rather than  pursuant
to this Prospectus.

The  Selling Security Holders may effect the above-mentioned
transactions  by  selling the Shares to or  through  broker-
dealers, and such broker-dealers may receive compensation in
the  form of discounts, concessions or commissions from  the
Selling Security Holders and/or the purchasers of the Shares
for  whom such broker-dealers may act as agents or  to  whom
they may sell as principals, or both (which compensation  as
to  a particular broker-dealer may be in excess of customary
commissions).   Any broker-dealer may act as a broker-dealer
on behalf of the Selling Security Holders in connection with
the  offering  of  certain  of the  Shares  by  the  Selling
Security  Holders.  Any broker-dealers who act in connection
with  the sale of the Shares hereunder may be deemed  to  be
"underwriters" within the meaning of Section  2(11)  of  the
Securities  Act, and any commissions received  by  them  and
profit  on  any  resale of the Shares as  principal  may  be
deemed  to  be underwriting discounts and commissions  under
the  Securities Act.  In order to comply with the securities
laws  of  certain states, if applicable, the Shares will  be
sold  in  such  jurisdictions,  if  required,  only  through
registered  or  licensed broker-dealers.   In  addition,  in
certain states, the Shares may not be sold unless the Shares
have been registered or qualified for sale in such state  or
an exemption from registration or qualification is available
and the conditions of such exemption have been satisfied.

None  of  the  proceeds from the sale of the Shares  by  the
Selling  Security Holders will be received by  the  Company.
There  can be no assurance that the Selling Security Holders
will  sell  any  or  all  of  the  Shares  offered  by  them
hereunder.

Under  applicable rules and regulations under  the  Exchange
Act,  any person engaged in distribution of Shares of Common
Stock offered hereby may not simultaneously engage in market
making  activities for the Common Stock for a period of  two
business   days   prior   to  the   commencement   of   such
distribution.  In addition, each Selling Security Holder and
any  other person who participates in a distribution of  the
Shares  will  be  subject to applicable  provisions  of  the
Exchange  Act  and  the  rules and  regulations  thereunder,
including Rule 10b-2, 10b-6 and 10b-7, which provisions  may
limit  the  timing of purchases and affect the marketability
of  the Shares of Common Stock and the ability of any person
to  engage  in  market making activities for the  shares  of
Common Stock.

The  Company has the right to suspend use of this Prospectus
for a discrete period of time under certain circumstances.

At  the time a particular offering of Shares is made, to the
extent required, a Prospectus Supplement will be distributed
which will set forth the number of Shares being offered  and
the  terms of the offering, including the purchase price  or
public   offering   price,  the  name  or   names   of   any
underwriters, dealers or agents, the purchase price paid  by
any  underwriter  for  Shares  purchased  from  the  Selling
Security Holders, any discounts commissions and other  items
constituting compensation from the Selling Security  Holders
and  any  discounts, commissions or concessions  allowed  or
reallowed or paid to dealers.

The  expenses  of the registration of the Shares  under  the
Securities Act, and the registration or qualification of the
Shares  under any applicable state securities laws  will  be
paid  by the Company.  The Company and each Selling Security
Holder have agreed to indemnify each other and certain other
persons  against certain liabilities in connection with  the
offering  of  the  Shares, including liabilities  under  the
Securities Act.

<PAGE>

                        LEGAL MATTERS

The  validity of the Shares offered hereby has  been  passed
upon  for  the Company by Stradley Ronon, Stevens  &  Young,
LLP, Philadelphia, PA.

                           EXPERTS

The   consolidated  financial  statements  of  the   Company
incorporated  by  reference in this  Registration  Statement
have been audited by Arthur Andersen LLP, Independent Public
Accountants,  as  indicated  in their  report  with  respect
thereto and are incorporated herein by reference in reliance
upon  the  authority of said firm as experts in giving  said
report.
                              
                                       
                              
                     EP MedSystems, Inc.
                              
                     2,250,000 SHARES OF
                        COMMON STOCK
                              
                         PROSPECTUS
                              
                         May    , 1998

<PAGE>


                           PART II
         INFORMATION NOT REQUIRED IN THE PROSPECTUS


Item 14.  Other Expenses of Issuance and Distribution

The following table sets forth the estimated expenses of the
registrant  in connection with the issuance and distribution
of   the  Shares  (all  amounts  are  estimated  except  the
Commission registration fee).  Selling commissions and  fees
and  stock  transfer taxes are payable individually  by  the
Selling Security Holders.

                                                  
Securities and Exchange Commission                
registration fee                          $  1,867
Blue sky filing fees and expenses           10,000
Legal fees and expenses                     30,000
Accountants' fees and expenses               3,000
Cost of printing                               500
Miscellaneous expenses                         633
                                           -------
          Total                            $46,000
                                           =======

Item 15.  Indemnification of Directors and Officers

Reference  is  made  to  Section 14A:3-5  of  the  New  Jersey
Business  Corporation Act, as amended, (the "BCA") which  sets
forth  the  extent  to which a corporation may  indemnify  its
directors,  officers and employees.  More  specifically,  such
law  empowers  a  corporation to indemnify a  corporate  agent
against  his  or  her  expenses and  liabilities  incurred  in
connection  with  any  proceeding  (other  than  a  derivative
lawsuit) involving the corporate agent by reason of his or her
being  or  having been a corporate agent if (a) the  corporate
agent  acted in good faith or in a manner he or she reasonably
believed to be in or not opposed to the best interests of  the
corporation, and (b) with respect to any criminal  proceeding,
the corporate agent had no reasonable cause to believe his  or
her  conduct was unlawful.  For purposes of such law the  term
"corporate  agent"  includes any present or  former  director,
officer,  employee or agent of the corporation, and  a  person
serving  as  a  "corporate  agent"  at  the  request  of   the
corporation   for   any  other  enterprise,   or   the   legal
representative   of  any  such  director,  officer,   trustee,
employee or agent.  For purposes of this section, "proceeding"
means  any  pending, threatened or completed civil,  criminal,
administrative or arbitrative action, suit, or proceeding, and
any  appeal  therein  and any inquiry or  investigation  which
could lead to such action, suit or proceeding.

With  respect  to  any derivative action, the  corporation  is
empowered  to indemnify a corporate agent against his  or  her
expenses  (but  not  his  or  her  liabilities)  incurred   in
connection  with any proceeding involving the corporate  agent
by reason of his or her being or having been a corporate agent
if  the  agent acted in good faith and in a manner he  or  she
reasonably  believed  to  be in or not  opposed  to  the  best
interests  of  the  corporation.  However, only  a  court  can
empower  a corporation to indemnify a corporate agent  against
expenses  with  respect to any claim, issue or  matter  as  to
which the agent was adjudged liable to the corporation.

The  corporation may indemnify a corporate agent in a specific
case  if a determination is made by any of the following  that
the  applicable standard of conduct was met: (i) the Board  of
Directors,  or a committee thereof, acting by a majority  vote
of  a  quorum consisting of disinterested directors;  (ii)  by
independent  legal  counsel, if  there  is  not  a  quorum  of
disinterested   directors  or  if  the  disinterested   quorum
empowers  counsel to make the determination; or (iii)  by  the
stockholders.

                            II-1


A  corporate agent is entitled to mandatory indemnification to
the  extent  that  the agent is successful on  the  merits  or
otherwise in any proceeding, or in defense of any claim, issue
or  matter  in  the  proceeding.  If a  corporation  fails  or
refuses   to   indemnify  a  corporate  agent,   whether   the
indemnification  is  permissive or mandatory,  the  agent  may
apply   to   a  court  to  grant  him  or  her  the  requested
indemnification.   In advance of the final  disposition  of  a
proceeding,  the Board of Directors may direct the corporation
to  pay  an agent's expenses if the agent agrees to repay  the
expenses in the event that it is ultimately determined that he
is not entitled to indemnification.

The  Company's Certificate of Incorporation and Bylaws provide
that  the  Company  may  indemnify  its  directors,  officers,
Scientific Advisory Board members, employees and other  agents
to  the  fullest extent permitted by New Jersey law; provided,
that  such  persons  acted  in good  faith  and  in  a  manner
reasonably believed to be in the best interest of the  Company
and,   with  respect  to  any  criminal  proceeding,  had   no
reasonable  cause  to believe such conduct was  unlawful.  The
Company  also  maintains liability insurance for its  officers
and  directors. There can be no assurance, however,  that  the
Company  will be able to maintain such insurance on reasonable
terms.

In  addition, Section 14A:2-7 of the BCA provides that  a  New
Jersey  corporation  may  include within  its  Certificate  of
Incorporation provisions eliminating or limiting the  personal
liability of its directors and officers in shareholder actions
brought  to  obtain damages for alleged breaches of  fiduciary
duties,  as  long  as the alleged acts or  omissions  did  not
involve  a  breach of a duty of loyalty to the corporation  or
its  shareholders,  were  performed in  good  faith,  did  not
involve  a  knowing violation of law or result in an  improper
personal benefit.

The  Company's Certificate of Incorporation and Bylaws provide
that  a  director of the Company will not be personally liable
to  the Company or its shareholders for damages for breach  of
any  duty owed to the Company or its shareholders, except  for
liabilities arising from any breach of duty based upon an  act
or  omission  (i)  in breach of the duty  of  loyalty  to  the
Company,  (ii)  not  in  good faith  or  involving  a  knowing
violation  of  law  or  (iii) resulting  in  receipt  by  such
director or officer of an improper personal benefit.

                            II-2

                              
Item 16.  Exhibits.

Exhibit Number      Description
- -------------       -----------
      4.1           Common Stock Purchase Agreement, dated  April  9,
                    1998,  among  the  Company and each of the Selling
                    Security Holders  (filed  as  Exhibit 4.1 to  the
                    Company's  Current Report  on   Form 8-K dated April
                    14, 1998 and  incorporated herein by reference).

      4.2           Registration Rights Agreement,  dated  April  9,
                    1998,  among  the  Company and each of the Selling
                    Security Holders  (filed  as  Exhibit 4.2 to  the  
                    Company's  Current Report  on  Form  8-K dated April
                    14, 1998 and  incorporated herein by reference).

      5.1           Opinion of Stradley Ronon, Stevens & Young, LLP,
                    regarding the legality of the Shares.  (Previously
                    filed and incorporated herein by reference).

     23.1           Consent of Arthur Andersen LLP.

     23.2           Consent of Stradley Ronon, Stevens & Young,  LLP
                    (contained in Exhibit 5.1).



                            II-3

<PAGE>
      
                        
Item 17.  Undertakings
                              
The undersigned registrant hereby undertakes:
     1.   To file, during any period in which offers or sales are
     being made, a post-effective amendment to this registration
     statement:
     
          a)   To include any prospectus required by Section 10(a)(3)
               of the Securities Act of 1933, as amended (the "Securities
               Act");

          b)   To reflect in the prospectus any facts or events
               arising after the effective date of the registration
               statement (or the most recent post-effective amendment
               thereof) which, individually or in the aggregate, represent
               a fundamental change in the information set forth in the
               registration statement; and

          c)   To include any material information with respect to the
               plan of distribution not previously disclosed in the
               registration statement or any material change to such
               information in the registration statement.
     
                Provided,  however, that the registrant
     does  not  need to make post-effective  amendments
     with  respect  to  the information  set  forth  in
     paragraphs a) and b) above if such information  is
     contained  in  periodic  reports  filed  with  the
     Commission  by the registrant under  the  Exchange
     Act   and   such   periodic  reports   have   been
     incorporated  by  reference in  this  registration
     statement.
     
     2.   That, for the purpose of determining any liability
     under the Securities Act, each such post-effective amendment
     shall be deemed to be a new registration statement relating
     to the securities offered therein, and the offering of such
     securities at that time shall be deemed to be the initial
     bona fide offering thereof.
     
     3.    To  remove from registration by means of a  post-
     effective amendment any of the Securities being registered
     that remain unsold after the termination of the offering.

     4.   The undersigned registrant hereby undertakes that, for
     purposes of determining any liability under the Securities
     Act, each filing of the registrant's annual report pursuant
     to Section 13(a) or Section 15(d) of the Exchange Act that
     is incorporated by reference in this registration statement
     shall be deemed to be a new registration statement relating
     to the securities offered therein, and the offering of such
     securities at that time shall be deemed to be the initial
     bona fide offering thereof.
     
     5.   Insofar as indemnification for liabilities arising
     under the Securities Act may be permitted to directors,
     officers and controlling persons of the registrant pursuant
     to the foregoing provisions, or otherwise, the registrant
     has been advised that in the opinion of the Securities and
     Exchange Commission such indemnification is against public
     policy as expressed in the Securities Act and is, therefore,
     unenforceable.   In  the  event  that   a   claim   for
     indemnification against such liabilities (other than the
     payment by the registrant of expenses incurred or paid by a
     director, officer or controlling person of the registrant in
     the successful defense of any action, suit or proceeding) is
     asserted by such director, officer or controlling person in
     connection  with  the securities being registered,  the
     registrant will, unless in the opinion of its counsel the
     matter has been settled by controlling precedent, submit to
     a court of appropriate jurisdiction the question  whether
     such indemnification by it is against public policy  as
     expressed in the Securities Act and will be governed by the
     final adjudication of such issue.


                            II-4

<PAGE>

                         SIGNATURES
Pursuant to the requirements of the Securities Act of  1933,
as  amended, the registrant certifies that it has reasonable
grounds to believe that it meets all of the requirements for
filing on Form S-3 and has duly caused this Amendment No.  1
to  Registration Statement to be signed on its behalf by the
undersigned, thereto duly authorized, in the City  of  Mount
Arlington, State of New Jersey, on May 15, 1998.

                              EP MedSystems, Inc.

                              By:  /s/ David A. Jenkins
                                       David A. Jenkins
                                   Chairman of the Board and
                                   Chief Executive Officer

Pursuant to the requirements of the Securities Act of  1933,
as  amended, this Amendment No. 1 to Registration  Statement
has  been  signed by the following persons in the capacities
and on the dates indicated.

     Signature                               Date
     ----------------                        -------------
/s/  David A. Jenkins                        May  15, 1998
     David A. Jenkins, Chairman,             
     President and Chief Executive Officer
     (Principal Executive Officer)           
                                             
/s/  James J. Caruso                         May  15, 1998
     James J. Caruso, Chief Financial
     Officer and Secretary 
     (Principal Accounting Officer)          
                                             
/s/  David W. Mortara, Ph.D.                 May 15, 1998
     David W. Mortara, Ph.D.                 
     Director                                
                                             
/s/  Lester J. Swenson                       May  15, 1998
     Lester J. Swenson                       
     Director                                
                                             
/s/  Anthony J. Varrichio                    May  15, 1998
     Anthony J. Varrichio                    
     Director                                
                              
                            II-5

<PAGE>

                    EXHIBIT INDEX

Exhibit No.         Description
- -----------         -----------
    4.1             Common Stock Purchase Agreement, dated April  9,
                    1998,  between the Company and each of the Selling
                    Security Holders  (filed  as  Exhibit 4.1 to  the
                    Company's  Current Report  on  Form  8-K dated April
                    14, 1998 and  incorporated herein by reference).

    4.2             Registration Rights Agreement,  dated  April  9,
                    1998,  between the Company and each of the Selling
                    Security Holders  (filed  as  Exhibit 4.2 to  the
                    Company's  Current Report  on  Form  8-K dated April
                    14, 1998 and  incorporated herein by reference).

    5.1             Opinion of Stradley Ronon, Stevens & Young,  LLP
                    regarding the legality of the Shares. (Previously
                    filed  and incorporated herein by reference).

   23.1             Consent of Arthur Andersen LLP.

   23.2             Consent of Stradley Ronon, Stevens & Young, LLP
                   (contained in Exhibit 5.1)

<PAGE>


                                                EXHIBIT 23.1

Consent   of   Arthur   Andersen  LLP,  Independent   Public
Accountants

As  independent public accountants, we hereby consent to the
incorporation by reference in this registration statement of
our  report dated March 11, 1998, included in EP MedSystems,
Inc.'s Form 10-KSB for the year ended December 31, 1997  and
to  all  references to our firm included or incorporated  by
reference in this registration statement.


                                     /s/ Arthur Andersen LLP

New York, New York
May 14, 1998



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