EP MEDSYSTEMS INC
424B1, 1998-07-15
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
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             SUBJECT TO COMPLETION, DATED JULY 6, 1998

PROSPECTUS

                     EP MEDSYSTEMS, INC.
              2,250,000 Shares of Common Stock
                              
This Prospectus relates to 2,250,000 shares of common stock,
no par value, stated value $.001 per share ("Common Stock"),
of  EP  MedSystems,  Inc.,  a New  Jersey  corporation  (the
"Company"),  which  may be offered  from  time  to  time  by
certain  security  holders  of  the  Company  (the  "Selling
Security   Holders"),   or   by  their   pledgees,   donees,
transferees or other  successors in interest, to or  through
underwriters  or  directly to other  purchasers  or  through
brokers  or  agents in one or more transactions  at  varying
prices  determined  at  the time of  sale  or  at  fixed  or
negotiated prices.  See "Plan of Distribution."

The  Company will not receive any of the proceeds  from  the
sale  of the 2,250,000 shares of Common Stock (the "Shares")
offered  hereby  by  the  Selling  Security  Holders.    The
expenses  of  the  registration  of  the  Shares  under  the
Securities  Act of 1933, as amended (the "Securities  Act"),
and  the  registration or qualification of the Shares  under
any  applicable state securities laws will be  paid  by  the
Company.   The  aggregate proceeds to the  Selling  Security
Holders will be the offering price of the Shares sold,  less
applicable  agents' commissions and underwriting  discounts,
if any.

All  of  the Shares were "restricted securities"  under  the
Securities  Act prior to their registration hereunder.   The
Company  sold  all  of  the Shares to the  Selling  Security
Holders  in  a  private transaction on April 9,  1998.   The
shares  of  Common Stock sold in such transaction constitute
the Shares being registered hereunder.

The  Common  Stock is traded on the Nasdaq  National  Market
("Nasdaq") under the symbol "EPMD."  On July 2, 1998,  the
last reported sale price of the Common Stock was $2.625 per
share.

The securities offered hereby involve a high degree of risk.
                     See "Risk Factors."

THESE  SECURITIES HAVE NOT BEEN APPROVED OR  DISAPPROVED  BY
THE   SECURITIES  AND  EXCHANGE  COMMISSION,  OR  ANY  STATE
SECURITIES  COMMISSION NOR HAS THE SECURITIES  AND  EXCHANGE
COMMISSION  OR ANY STATE SECURITIES COMMISSION  PASSED  UPON
THE   ACCURACY   OR   ADEQUACY  OF  THIS   PROSPECTUS.   ANY
REPRESENTATION TO THE CONTRARY IS A CRIMINAL OFFENSE.

                                                        Proceeds to
                        Underwriting      Proceeds        Selling
            Price to    Discounts and        to          Security
           Public (1)  Commissions (2)  Company (3)     Holders (4)
           ---------   ---------------  -----------     -----------
Per Share   $2.625           --              --         $2.625
Total      $5,906,250        --              --         $5,906,250

1. Represents the last reported sale price per  share  of
Common Stock on Nasdaq on July 2, 1998.
2. Cannot be estimated at this time.
3. The Company will pay estimated expenses of $46,000  in
connection with the offering of the Shares by the  Selling
Security Holders.
4. Before   applicable   underwriting   discounts    or
commissions, which cannot be estimated at this time.

             The date of this Prospectus is July 6, 1998

<PAGE>

No  dealer,  salesperson or other person has been authorized
to give any information or to make any representations other
than  those  contained in this Prospectus and, if  given  or
made, such information or representations must not be relied
upon as having been authorized by the Company.  Neither  the
delivery  of  this  Prospectus nor any sale  made  hereunder
shall,  under any circumstances, create any indication  that
there has been no change in the affairs of the Company since
the date hereof or that the information contained herein  is
correct as of any date subsequent to the date hereof.   This
Prospectus  does  not  constitute an  offer  to  sell  or  a
solicitation  of  an  offer to buy  any  securities  offered
hereby by anyone in any jurisdiction in which such offer  or
solicitation is not authorized or in which the person making
such  offer or solicitation is not qualified to do so or  to
anyone  to  whom  it  is  unlawful to  make  such  offer  or
solicitation.
                              

                      TABLE OF CONTENTS
                                                     Page
Available Information                                 1
Incorporation of Certain Documents by Reference       2
Forward Looking Statements                            2
Risk Factors                                          3
The Company                                           3
Use of Proceeds                                       3
Selling Security Holders                              4
Plan of Distribution                                  5
Legal Matters                                         6
Experts                                               6

                    AVAILABLE INFORMATION
                              
The  Company has filed with the U.S. Securities and Exchange
Commission  (the "Commission") a Registration  Statement  on
Form S-3 (the "Registration Statement") under the Securities
Act  with  respect to the Shares of Common Stock offered  by
this  Prospectus.  This Prospectus, filed  as  part  of  the
Registration  Statement,  does  not  contain  all   of   the
information set forth in the Registration Statement and  the
exhibits  and schedules thereto, certain portions  of  which
have  been omitted in accordance with the Commission's rules
and  regulations.  For further information with  respect  to
the Company and the Shares offered hereby, reference is made
to  the  Registration  Statement and  to  the  exhibits  and
schedules   filed   therewith.   The  statements   in   this
Prospectus  are qualified in their entirety by reference  to
the contents of any agreement or other document incorporated
herein  by reference, a copy of which is filed as an exhibit
to either the Registration Statement or other filings by the
Company  with  the  Commission.  A copy of the  Registration
Statement   may   be  inspected  without   charge   at   the
Commission's  principal offices, and copies of  all  or  any
part of the Registration Statement may be obtained from such
office   upon  payment  of  the  fees  prescribed   by   the
Commission.

The Company is subject to the informational requirements  of
the  Securities  Exchange  Act  of  1934,  as  amended  (the
"Exchange Act"), and in accordance therewith, files reports,
proxy  statements and other information with the Commission.
Such  reports, proxy statements and other information  filed
by  the  Company may be inspected and copied (at  prescribed
rates) at the public reference facilities maintained by  the
Commission in Washington, D.C. (450 Fifth Street, N.W., Room
1024,  Judiciary Plaza, Washington, D.C. 20549) and  at  the
Commission's  Regional Offices in New York  (7  World  Trade
Center,  13th Floor, New York, New York 10048)  and  Chicago
(Citicorp  Center,  500  West Madison  Street,  Suite  1400,
Chicago,  Illinois  60661).  The Company  is  an  electronic
filer  and the Commission maintains a web site that contains
reports,   proxy  and  information  statements   and   other
information  regarding registrants that file  electronically
with  the  Commission.   The address  of  the  web  site  is
"http://www.sec.gov."   The   Company's    reports,    proxy
statements  and other information may also be  inspected  at
the  offices  of  the  National  Association  of  Securities
Dealers, Inc., 1735 K Street, N.W., Washington, D.C. 20006.

<PAGE>

       INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE
                              
The  following  documents filed with the Commission  by  the
Company are incorporated by reference into this Prospectus:

(1)  The Company's Annual Report on Form 10-KSB for the year
ended December 31, 1997;

(2)  The Company's Quarterly Report on Form 10-QSB for the
quarter ended March 31, 1998;

(3)  The Company's Current Report on Form 8-K dated April
14, 1998;

(4)  The description of the Common Stock contained in the
Company's Registration Statement on Form 8-A filed April 19,
1996; and

All  documents  filed  with the Commission  by  the  Company
pursuant  to  Section  13(a), 13(c),  14  or  15(d)  of  the
Exchange  Act subsequent to the date of this Prospectus  and
prior to the termination of the offering of the Shares shall
be   deemed  to  be  incorporated  by  reference  into  this
Prospectus and to be a part hereof from the respective dates
of  filing  such  documents.  Any statement contained  in  a
document  incorporated  or  deemed  to  be  incorporated  by
reference  herein  shall be deemed modified,  superseded  or
replaced for purposes of this Prospectus to the extent  that
a  statement  contained herein or in any subsequently  filed
document  that  also is or is deemed to be  incorporated  by
reference  herein  modifies,  supersedes  or  replaces  such
statement.    Any  statement  so  modified,  superseded   or
replaced  shall  not  be  deemed,  except  as  so  modified,
superseded  or  replaced,  to  constitute  a  part  of  this
Prospectus.

The  Company  will provide without charge  to  each  person,
including  any beneficial owner of Common Stock, to  whom  a
copy  of  this  Prospectus is delivered, upon such  person's
written  or  oral  request, a copy of any  and  all  of  the
documents  incorporated  by  reference  herein  (other  than
exhibits  to  such  documents,  unless  such  exhibits   are
specifically incorporated by reference into the  information
that  this  Prospectus incorporates).   Requests  should  be
directed  to  EP MedSystems, Inc. 100 Stierli  Court,  Mount
Arlington,   NJ   07856,  Attention:  Corporate   Secretary,
telephone: (973) 398-2800.

                 FORWARD-LOOKING STATEMENTS
                              
In  addition  to  historical  information,  this  Prospectus
contains forward-looking statements relating to such matters
as anticipated  financial  and  operational  performance,
business prospects, technological developments, results of
clinical  trials,  new  products, research  and  development
activities  and  similar  matters.  The  Private  Securities
Litigation  Reform Act of 1995 provides a  safe  harbor  for
forward-looking  statements.   The  Company  notes  that   a
variety  of factors could cause the Company's actual results
and  experience  to differ materially from  the  anticipated
results  or  other expectations expressed in  the  Company's
forward-looking  statements.  When used in this  Prospectus,
the  words  or phrases "believes," "anticipates," "expects,"
"intends," "will likely result," "estimates," "projects"  or
similar  expressions are intended to identify such  forward-
looking  statements,  but are not  the  exclusive  means  of
identifying    such   statements.    Such    forward-looking
statements  are only predictions, and the actual  events  or
results may differ materially from the results discussed  in
the forward-looking statements.  Factors that could cause or
contribute to such differences include, but are not  limited
to,  those matters discussed herein in the section  entitled
"Risk Factors."

The  Company  cautions  readers  to  review  the  cautionary
statements set forth in this Prospectus and in the Company's
other   reports  filed  with  the  Securities  and  Exchange
Commission and cautions that other factors may prove  to  be
important in affecting the Company's business and results of
operations.   Readers  are  cautioned  not  to  place  undue
reliance  on  these forward-looking statements, which  speak
only  as of the date of this report.  The Company undertakes
no  obligation  to  publicly  revise  these  forward-looking
statements  to  reflect events or circumstances  that  arise
after the date of this report.
                              
<PAGE>


                        RISK FACTORS
                              
An  investment in the Company's Common Stock is  speculative
in nature, involves a high degree of risk and should only be
made  by  an investor who can afford the loss of his  entire
investment. Prospective purchasers should carefully consider
the  risk  factors contained in the section titled  "Factors
That  May Impact Future Operations" in the Company's  Annual
Report on Form 10-KSB and other periodic reports filed under
the Exchange Act, as well as the other information set forth
in  this  Prospectus, before purchasing the  Shares  offered
hereby.  Such risk factors could cause the Company's  actual
results  to  differ materially from those expressed  in  the
Company's  forward-looking statements in this Prospectus  or
have  a material adverse effect upon the Company's business,
results of operations, prospects and financial condition.

                         THE COMPANY

EP  MedSystems, Inc.  designs, manufactures  and  markets  a
broad-based    line   of   products    for    the    cardiac
electrophysiology   ("EP")  market  for   the   purpose   of
diagnosing,  monitoring,  managing  and  treating  irregular
heartbeats known as arrhythmias.  This product line includes
the  EP  WorkMate,  a computerized monitoring  and  analysis
workstation  (the  "EP  WorkMate"),  the  EP-3  computerized
electrophysiology stimulator (the "EP-3 Stimulator" or  "EP-
3")  and  the PaceBase/TeleTrace III receiver, an integrated
ECG  monitoring device and computerized transmission  system
for automation of pacemaker and arrhythmia follow-up testing
and   data  archiving.   The  Company's  product  line  also
includes  diagnostic electrophysiology catheters,  temporary
pacing catheters and related disposable supplies.

The  Company  has also developed a new product for  internal
cardioversion  of  atrial fibrillation known  as  the  ALERT
System (the "ALERT System"), which uses a patented electrode
catheter   to   deliver  measured,  variable,   low   energy
electrical impulses directly to the inside of the  heart  in
order  to  convert  atrial fibrillation to  a  normal  heart
rhythm.   As  of  July 6, 1998,  the  ALERT  System is
undergoing clinical trials in the United States.

The Company was incorporated in New Jersey in January, 1993.
The  Company's principal offices are located at 100  Stierli
Court,  Mount Arlington, NJ 07856, and its telephone  number
is 973-398-2800.


                       USE OF PROCEEDS
                              
The  Company will not receive any of the proceeds  from  the
sale of the Shares by the Selling Security Holders.  The net
proceeds from the sale of the Shares will be received by the
Selling Security Holders.

<PAGE>


                  SELLING SECURITY HOLDERS
The  following table sets forth information as of April  17,
1998  with respect to each of the Selling Security  Holders,
including their respective names, record holdings of  shares
of  the Company's Common Stock owned before the offering  of
the  Shares,  the  number of shares of  Common  Stock  being
offered for each of their respective accounts and the number
of  shares of Common Stock to be owned of record by each  of
them immediately following the sale of the shares.

                           Shares of      Shares of         Common
                            Common          Common         Stock to
       Name of            Stock Owned    Stock Being       be Owned
   Selling Security         Before         Offered        After the
        Holder             Offering        (1) (2)         Offering
- ----------------------    -----------    -----------      ---------
SC Fundamental Value                                         
Fund, LP (3)                376,800        339,500          37,300
10 East 50th Street                                            
New York, NY 10022                                             
                                                               
SC Fundamental Value                                         
BVI, Ltd. (3)               373,200        335,500          37,700
c/o SC BVI Partners                                            
10 East 50th Street                                            
New York, NY 10022                                             
                                                               
H & Q Life Sciences                                         
Investors (3) (4)           430,000        430,000            0
50 Rowes Wharf                                                 
Boston, MA 02110-6679                                          
                                                               
H & Q Healthcare                                         
Investors (3) (4)           645,000        645,000            0
50 Rowes Wharf                                                 
Boston, MA 02110-6679                                          
                                                               
Special Situations                                         
Fund III LP (3)             411,000        375,000          36,000
153 East 53rd Street                                           
New York, NY 10022                                             
                                                               
Special Situations                                         
Cayman Fund (3)             137,000        125,000          12,000
153 East 53rd Street                                     
New York, NY 10022                                       

(1)   Assumes the sale of all the Shares offered by each  of
the Selling Security Holders.

(2)    On  April  9,  1998,  the  Selling  Security  Holders
purchased  2,250,000 Shares of Common Stock in  a  private
placement of such securities conducted by the Company.  The
aggregate offering proceeds from the sale of the Shares was
$5,062,500, based on a per share price of $2.25. The Company
intends  to use the proceeds of the private placement  for
working capital and general corporate purposes.

(3)   SC Fundamental Value Fund, LP and SC Fundamental Value
BVI,  Ltd.  share  common management.  H&Q  Life  Sciences
Investors  and  H&Q  Healthcare  Investors  share   common
management.  The management companies of Special Situations
Fund III LP and Special Situations Cayman Fund share certain
common ownership.

(4)  H&Q Life Sciences Investors and H&Q Healthcare
Investors are significant shareholders of the Company by
virtue of their holding in the aggregate greater than 10% of
the issued and outstanding common stock.

Except  as  described  above, none of the  Selling  Security
Holders has held any position or office or has had any other
material  relationship  with the  Company,  or  any  of  its
affiliates, within the past three years.

<PAGE>

                    PLAN OF DISTRIBUTION

All  of  the Shares offered hereby may be sold from time  to
time  by the Selling Security Holders, or by their permitted
assigns or permitted transferees.  The sale of the Shares by
the  Selling Security Holders may be effected from  time  to
time in transactions through Nasdaq, or on one or more other
securities  markets and exchanges on which  the  Shares  are
then  listed, in privately negotiated transactions,  through
the  writing  of  options on the Shares,  or  otherwise,  or
through  a  combination of such methods of  sale,  at  fixed
prices  that may be changed, at market prices prevailing  at
the  time  of  sale, at prices relating to  such  prevailing
market prices or at negotiated prices.  In addition, any  of
the  Shares  that  qualify for sale  pursuant  to  Rule  144
promulgated  under  the  Securities  Act  may  be  sold   in
transactions complying with such Rule, rather than  pursuant
to this Prospectus.

The  Selling Security Holders may effect the above-mentioned
transactions  by  selling the Shares to or  through  broker-
dealers, and such broker-dealers may receive compensation in
the  form of discounts, concessions or commissions from  the
Selling Security Holders and/or the purchasers of the Shares
for  whom such broker-dealers may act as agents or  to  whom
they may sell as principals, or both (which compensation  as
to  a particular broker-dealer may be in excess of customary
commissions).   Any broker-dealer may act as a broker-dealer
on behalf of the Selling Security Holders in connection with
the  offering  of  certain  of the  Shares  by  the  Selling
Security  Holders.  Any broker-dealers who act in connection
with  the sale of the Shares hereunder may be deemed  to  be
"underwriters" within the meaning of Section  2(11)  of  the
Securities  Act, and any commissions received  by  them  and
profit  on  any  resale of the Shares as  principal  may  be
deemed  to  be underwriting discounts and commissions  under
the  Securities Act.  In order to comply with the securities
laws  of  certain states, if applicable, the Shares will  be
sold  in  such  jurisdictions,  if  required,  only  through
registered  or  licensed broker-dealers.   In  addition,  in
certain states, the Shares may not be sold unless the Shares
have been registered or qualified for sale in such state  or
an exemption from registration or qualification is available
and the conditions of such exemption have been satisfied.

None  of  the  proceeds from the sale of the Shares  by  the
Selling  Security Holders will be received by  the  Company.
There  can be no assurance that the Selling Security Holders
will  sell  any  or  all  of  the  Shares  offered  by  them
hereunder.

Each Selling Security Holder and any  other person who
participates in a distribution of the Shares  will  be
subject to applicable  provisions  of  the Exchange  Act
and  the  rules and  regulations  thereunder, including
the anti-manipulation rules of Regulation M, which provisions
may limit  the  timing of purchases and affect the marketability
of the Shares of Common Stock and the ability of any person to 
engage  in  market making activities for the shares of Common Stock.

The  Company has the right to suspend use of this Prospectus
under certain circumstances for a period of not more than
sixty days in any twelve month period.  The Company expects
it might exercise such right if a preliminary corporate development
would exist which may materially affect the Company's stock price
and such development has not been appropriately publicly disclosed.

At  the time a particular offering of Shares is made, to the
extent required, a Prospectus Supplement will be distributed
which will set forth the number of Shares being offered  and
the  terms of the offering, including the purchase price  or
public   offering   price,  the  name  or   names   of   any
underwriters, dealers or agents, the purchase price paid  by
any  underwriter  for  Shares  purchased  from  the  Selling
Security Holders, any discounts commissions and other  items
constituting compensation from the Selling Security  Holders
and  any  discounts, commissions or concessions  allowed  or
reallowed or paid to dealers.

The  expenses  of the registration of the Shares  under  the
Securities Act, and the registration or qualification of the
Shares  under any applicable state securities laws  will  be
paid  by the Company.  The Company and each Selling Security
Holder have agreed to indemnify each other and certain other
persons  against certain liabilities in connection with  the
offering  of  the  Shares, including liabilities  under  the
Securities Act.

<PAGE>

                        LEGAL MATTERS

The  validity of the Shares offered hereby has  been  passed
upon  for  the Company by Stradley Ronon, Stevens  &  Young,
LLP, Philadelphia, PA.

                           EXPERTS

The   consolidated  financial  statements  of  the   Company
incorporated  by  reference in this  Registration  Statement
have been audited by Arthur Andersen LLP, Independent Public
Accountants,  as  indicated  in their  report  with  respect
thereto and are incorporated herein by reference in reliance
upon  the  authority of said firm as experts in giving  said
report.
                              
                                       
                              
                     EP MedSystems, Inc.
                              
                      2,250,000 SHARES OF
                        COMMON STOCK
                              
                          PROSPECTUS
                              
                         July 6, 1998




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