APPLIED ANALYTICAL INDUSTRIES INC
8-K, 1999-10-27
MEDICAL LABORATORIES
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                       SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549


                                    FORM 8-K

                                 CURRENT REPORT


     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934



        Date of Report (Date of earliest event reported) October 21, 1999



                       APPLIED ANALYTICAL INDUSTRIES, INC.
             ------------------------------------------------------
             (Exact Name of Registrant as Specified in its Charter)


<TABLE>
<CAPTION>


<S>                                             <C>                                            <C>
             Delaware                                    0-21185                                   04-2687849
- -----------------------------                   ------------------------                       -------------------
(State or Other Jurisdiction                    (Commission File Number)                        (I.R.S. Employer
        of Incorporation)                                                                      Identification No.)
</TABLE>


                           2320 Scientific Park Drive
                        Wilmington, North Carolina 28405
                    ----------------------------------------
                    (Address of Principal Executive Offices)
                                   (Zip Code)


                                 (910) 254-7000
              ----------------------------------------------------
              (Registrant's Telephone Number, Including Area Code)


                             5051 New Centre Drive
                        Wilmington, North Carolina 28403
              -----------------------------------------------------
              (Former name or address, if changed from last report)

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Item 5.           Other Events.


        On October 21, 1999, Applied Analytical Industries, Inc. (the "Company")
issued a press release regarding the Company's third quarter results which,
based on preliminary information, are expected to fall below analysts' estimates
for the period ending September 30, 1999. The press release is filed as Exhibit
99.1 hereto and is incorporated by reference herein.

Item 7.           Financial Statements and Exhibits.

         (a)      Financial Statements

                  Not applicable.

         (b)      Pro Forma Financial Information

                  Not applicable.

         (c)      Exhibits

                  Exhibit 99.1  --  Press release dated October 21, 1999



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<PAGE>   3


                                   SIGNATURES

          Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

Date: October 27, 1999

                                 APPLIED ANALYTICAL INDUSTRIES, INC.


                                 By: /s/ Eugene T. Haley
                                    ------------------------------------------
                                    Eugene T. Haley
                                    Vice President and Chief Financial Officer



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<PAGE>   4


                                  EXHIBIT INDEX


         Exhibit No.                  Exhibit
         -----------                  -------

         Exhibit 99.1                 Press release dated October 21, 1999



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<PAGE>   1




APPLIED ANALYTICAL INDUSTRIES, INC. MAKES ANNOUNCEMENT
REGARDING THIRD QUARTER DEVELOPMENTS

Wilmington, NC, October 21, 1999-- Applied Analytical Industries, Inc.,
(Nasdaq:AAII) announced today that based on preliminary information, earnings
for the third quarter ended September 30, 1999, while showing improvement over
second quarter results, are expected to fall below analysts' currently published
estimates.

Dr. Fred Sancilio, president and CEO of AAI, stated, "As we discussed at the end
of the second quarter, we are signing larger and more profitable contracts, but
these larger projects have longer lead-in and start-up times. Although we signed
several of these larger contracts late in the second quarter and during the
third quarter, work on them commenced late in the third quarter and thus had
minimal impact on our third quarter results. Despite this anticipated quarterly
loss, we saw meaningful improvement in our operations quarter-over-quarter and
made significant progress on several of our product development negotiations. We
look forward to providing additional information about our quarterly results and
recent positive business developments in our proton pump inhibitor (PPI) program
and its associated intellectual property at our scheduled conference call on
November 2nd."

The telephone conference to discuss the third quarter 1999 results will be held
on Tuesday, November 2, 1999, 8:30 AM Eastern Standard Time. The call-in numbers
are:

800-289-0437 for domestic callers
913-981-5508 for international callers.

Please reference confirmation code 802504.

Information in this press release contains certain "forward-looking statements"
within the meaning of Section 27A of the Securities Act of 1933 and Section 2lE
of the Securities Exchange Act of 1934. These statements involve risks and
uncertainties that could cause actual results to differ materially, including
without limitation, the ability of acquired businesses to be integrated with
AAI's operations, actual operational performance, the ability to meet projected
revenue and earnings, the ability to acquire and maintain large client
contracts, the ability to hire and retain qualified employees and other items
that may cause the actual results to differ materially, which may be discussed
in the Company's recent Form 1O-K filings, its registration statement, as
amended, and other filings with the Securities and Exchange Commission.

                                       ###

For further information contact Meg Humphrey, VP of Strategic Planning and
Investor Relations, AAI at 704.367.5119 or [email protected].



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