GENETIC VECTORS INC
S-8 POS, 2000-11-08
PHARMACEUTICAL PREPARATIONS
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    As filed with the Securities and Exchange Commission on November 8, 2000

                                                       Registration No. 333-5530

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                             -----------------------
                   POST-EFFECTIVE AMENDMENT NO. 1 TO FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933
                             -----------------------
                              GENETIC VECTORS, INC.
             (Exact Name of Registrant as Specified in Its Charter)

                                     FLORIDA
         (State or Other Jurisdiction of Incorporation or Organization)

                                   65-0324710
                      (I.R.S. Employer Identification No.)

                        5201 N.W. 77TH AVENUE, SUITE 100
                              MIAMI, FLORIDA 33166
                    (Address of Principal Executive Offices)

                    GENETIC VECTORS, INC. 1996 INCENTIVE PLAN
                       JAMES A. JOYCE CONSULTING AGREEMENT
                            (Full Title of the Plan)

                               MEAD M. MCCABE, JR.
                        5201 N.W. 77TH AVENUE, SUITE 100
                              MIAMI, FLORIDA 33166
                     (Name and Address of Agent For Service)

                                 (305) 716-0000
          (Telephone Number, Including Area Code, of Agent for Service)

                                    Copy to:
                             Clayton E. Parker, Esq.
                           Kirkpatrick & Lockhart LLP
                    201 South Biscayne Boulevard, 20th Floor
                              Miami, Florida 33131


<PAGE>


                                     PART I
                                     ------

                          INFORMATION REQUIRED IN THIS
                            SECTION 10(A) PROSPECTUS

         The documents  containing the  information  specified in Part I of Form
S-8  (plan  information  and  registrant  information)  will be sent or given to
employees as  specified by Rule  428(b)(1)  of the  Securities  Act of 1933,  as
amended (the "Act").  Such  documents  need not be filed with the Securities and
Exchange  Commission  either  as  part  of  this  Registration  Statement  or as
prospectuses or prospectus  supplements  pursuant to Rule 424. These  documents,
which include the statement of availability  required by Item 2 of Form S-8, and
the documents  incorporated by reference in this Registration Statement pursuant
to Item 3 of Form S-8 (Part II hereof), taken together,  constitute a prospectus
that meets the requirements of Section 10(a) of the Act.

                                     PART II
                                     -------

                          INFORMATION REQUIRED IN THIS
                             REGISTRATION STATEMENT

ITEM 3.  INCORPORATION OF DOCUMENTS BY REFERENCE.
         ---------------------------------------

         The following  documents have been previously filed by Genetic Vectors,
Inc. (the "Company") with the Securities and Exchange  Commission and are hereby
incorporated  by  reference  into  this  Registration   Statement  as  of  their
respective dates:

         (a) The Company's Annual  Report on  Form  10-KSB for  the fiscal years
ended December 31, 1999 and 1998.

         (b) All other reports  filed  pursuant to Section 13(a) or 15(d) of the
Securities  Exchange Act of 1934, as amended (the "Exchange Act"), since the end
of the fiscal year covered by the registrant document referred to in (a) above.

         (c) The  description  of the  Company's  Common Stock  contained in its
Registration  Statement  on Form 8-A as filed with the  Securities  and Exchange
Commission  on November 15,  1996,  as amended,  pursuant to the  Exchange  Act,
including  any  amendment  or report  filed for the  purpose  of  updating  such
description.

         All documents subsequently filed by the Company with the Securities and
Exchange  Commission  pursuant to  Sections  13(a),  13(c),  14 and 15(d) of the
Securities Exchange Act of 1934, as amended, after the date of this Registration
Statement,  but  prior  to the  filing  of a  post-effective  amendment  to this
Registration  Statement  that  indicates  that all  securities  offered  by this
Registration  Statement have been sold or which  deregisters all such securities
then remaining unsold, shall be deemed to be incorporated by reference into this
Registration  Statement.  Each  document  incorporated  by  reference  into this
Registration  Statement  shall  be  deemed  to be a part  of  this  Registration
Statement  from the date of the filing of such document with the  Securities and
Exchange  Commission  until the information  contained  therein is superseded or
updated by any  subsequently  filed document that is  incorporated  by reference
into this Registration Statement or by any document that constitutes part of the
prospectus  relating to the Genetic  Vectors,  Inc. 1996  Incentive  Plan or the
James A. Joyce Consulting Agreement that meets the requirements of Section 10(a)
of the Securities Act of 1933, as amended.


                                        2
<PAGE>


ITEM 4.  DESCRIPTION OF SECURITIES.
         -------------------------

         Not Applicable.


ITEM 5.  INTERESTS OF NAMED EXPERTS AND COUNSEL.
         --------------------------------------

         Not Applicable

ITEM 6.  INDEMNIFICATION OF DIRECTORS AND OFFICERS.
         -----------------------------------------

         The Florida Business  Corporation Act ("FBCA") provides that in certain
cases,  each officer and  director of the Company  shall be  indemnified  by the
Company  against  certain costs,  expenses and  liabilities  which he or she may
incur in his or her capacity as such.  FBCA ss.  607.0850  ("Indemnification  of
officers, directors, employees and agents") provides:

         (1) A  corporation  shall have power to indemnify any person who was or
is a party to any  proceeding  (other than an action by, or in the right of, the
corporation),  by  reason  of the fact  that he is or was a  director,  officer,
employee, or agent of the corporation or is or was serving at the request of the
corporation as a director,  officer,  employee, or agent of another corporation,
partnership,  joint  venture,  trust,  or  other  enterprise  against  liability
incurred in connection with such proceeding, including any appeal thereof, if he
acted in good  faith and in a manner  he  reasonably  believed  to be in, or not
opposed to, the best  interests  of the  corporation  and,  with  respect to any
criminal  action or proceeding,  had no reasonable  cause to believe his conduct
was unlawful. The termination of any proceeding by judgment,  order, settlement,
or conviction or upon a plea of nolo contendere or its equivalent  shall not, of
itself,  create a presumption that the person did not act in good faith and in a
manner  which he  reasonably  believed  to be in, or not  opposed  to,  the best
interests  of the  corporation  or,  with  respect  to any  criminal  action  or
proceeding, had reasonable cause to believe that his conduct was unlawful.

         (2) A corporation shall have power to indemnify any person,  who was or
is a party to any proceeding by or in the right of the  corporation to procure a
judgment  in its  favor  by  reason  of the fact  that he is or was a  director,
officer,  employee,  or agent of the  corporation  or is or was  serving  at the
request of the corporation as a director, officer, employee, or agent of another
corporation,  partnership,  joint venture,  trust, or other enterprise,  against
expenses and amounts paid in settlement  not  exceeding,  in the judgment of the
board of  directors,  the  estimated  expense of  litigating  the  proceeding to
conclusion,  actually and reasonably  incurred in connection with the defense or
settlement   of  such   proceeding,   including   any   appeal   thereof.   Such
indemnification  shall be authorized if such person acted in good faith and in a
manner he reasonably believed to be in, or not opposed to, the best interests of
the  corporation,  except  that no  indemnification  shall  be made  under  this
subsection  in respect of any claim,  issue,  or matter as to which such  person
shall have been adjudged to be liable  unless,  and only to the extent that, the
court in which such  proceeding  was  brought,  or any other court of  competent
jurisdiction, shall determine upon application that, despite the adjudication of
liability but in view of all  circumstances  of the case,  such person is fairly
and  reasonably  entitled to indemnity for such expenses  which such court shall
deem proper.

         (3) To the extent that a  director,  officer,  employee,  or agent of a
corporation  has been  successful  on the merits or  otherwise in defense of any
proceeding referred to in subsection (1) or subsection (2), or in defense of any
claim,  issue,  or matter  therein,  he shall be  indemnified  against  expenses
actually and reasonably incurred by him in connection therewith.

         (4) Any indemnification  under subsection (1) or subsection (2), unless
pursuant to a determination by a court, shall be made by the corporation only as
authorized in the specific case upon a determination that indemnification of the
director,  officer, employee, or agent is proper in the circumstances because he


                                        3
<PAGE>


has met the  applicable  standard  of  conduct  set forth in  subsection  (1) or
subsection (2). Such determination shall be made:

              (a) By the  board  of  directors  by a  majority  vote of a quorum
consisting of directors who were not parties to such proceeding;

              (b) If such a quorum is not obtainable or, even if obtainable,  by
majority vote of a committee duly designated by the board of directors (in which
directors  who are parties  may  participate)  consisting  solely of two or more
directors not at the time parties to the proceeding;

              (c) By independent legal counsel;

                  1. Selected by the board of directors  prescribed in paragraph
(a) or the committee prescribed in paragraph (b); or

                  2.  If a  quorum  of the  directors  cannot  be  obtained  for
paragraph  (a) and the  committee  cannot be  designated  under  paragraph  (b),
selected by majority vote of the full board of directors (in which directors who
are parties may participate); or

              (d) By the shareholders by a majority vote of a quorum  consisting
of shareholders who were not parties to such proceeding or, if no such quorum is
obtainable,  by a majority  vote of  shareholders  who were not  parties to such
proceeding.

         (5) Evaluation of the  reasonableness  of expenses and authorization of
indemnification  shall  be made in the same  manner  as the  determination  that
indemnification is permissible.  However, if the determination of permissibility
is made by independent  legal  counsel,  persons  specified by paragraph  (4)(c)
shall evaluate the reasonableness of expenses and may authorize indemnification.

         (6) Expenses incurred by an officer or director in defending a civil or
criminal  proceeding  may be paid by the  corporation  in  advance  of the final
disposition of such proceeding upon receipt of an undertaking by or on behalf of
such director or officer to repay such amount if he is  ultimately  found not to
be entitled to  indemnification  by the  corporation  pursuant to this  section.
Expenses incurred by other employees and agents may be paid in advance upon such
terms or conditions that the board of directors deems appropriate.

         (7) The  indemnification  and advancement of expenses provided pursuant
to this  section  are not  exclusive,  and a  corporation  may make any other or
further  indemnification  or  advancement  of expenses of any of its  directors,
officers, employees, or agents, under any bylaw, agreement, vote of shareholders
or  disinterested  directors,  or  otherwise,  both as to action in his official
capacity  and as to  action in  another  capacity  while  holding  such  office.
However,  indemnification  or advancement of expenses shall not be made to or on
behalf of any director, officer, employee, or agent if a judgment or other final
adjudication establishes that his actions, or omissions to act, were material to
the cause of action so adjudicated and constitute:

              (a) A violation of the criminal law, unless the director, officer,
employee, or agent had reasonable cause to believe his conduct was lawful or had
no reasonable cause to believe his conduct was unlawful;

              (b) A transaction from which the director,  officer,  employee, or
agent derived an improper personal benefit;

              (c) In the case of a  director,  a  circumstance  under  which the
liability provisions ofss. 607.0834 are applicable; or

              (d) Willful  misconduct  or  a  conscious  disregard  for the best
interests  of  the  corporation  in a  proceeding  by or in  the  right  of  the
corporation  to procure a judgment in its favor or in a proceeding  by or in the
right of a shareholder.


                                        4
<PAGE>


         (8)  Indemnification  and  advancement  of expenses as provided in this
section  shall  continue  as,  unless  otherwise  provided  when  authorized  or
ratified,  to a person who has ceased to be a director,  officer,  employee,  or
agent and shall inure to the benefit of the heirs, executors, and administrators
of such a person, unless otherwise provided when authorized or ratified.

         (9)  Unless  the  corporation's   articles  of  incorporation   provide
otherwise,   notwithstanding   the   failure   of  a   corporation   to  provide
indemnification,  and despite any contrary  determination of the board or of the
shareholders in the specific case, a director,  officer,  employee,  or agent of
the  corporation  who  is  or  was  a  party  to  a  proceeding  may  apply  for
indemnification or advancement of expenses, or both, to the court conducting the
proceeding, to the circuit court, or to another court of competent jurisdiction.
On  receipt  of an  application,  the court,  after  giving  any notice  that it
considers  necessary,  may order  indemnification  and  advancement of expenses,
including  expenses  incurred  in  seeking   court-ordered   indemnification  or
advancement of expenses, if it determines that

              (a) The  director,  officer,  employee,  or agent is  entitled  to
mandatory  indemnification  under  subsection (3), in which case the court shall
also order the corporation to pay the director  reasonable  expenses incurred in
obtaining court-ordered indemnification or advancement of expenses;

              (b) The  director,  officer,  employee,  or agent is  entitled  to
indemnification  or advancement of expenses,  or both, by virtue of the exercise
by the corporation of its power pursuant to subsection (7); or

              (c) The  director,  officer,  employee,  or  agent is  fairly  and
reasonably  entitled to indemnification or advancement of expenses,  or both, in
view of all the relevant  circumstances,  regardless  of whether such person met
the  standard  of  conduct  set forth in  subsection  (1),  subsection  (2),  or
subsection (7).

         (10) For purposes of this section, the term "corporation"  includes, in
addition to the resulting  corporation,  any constituent  corporation (including
any constituent of a constituent) absorbed in a consolidation or merger, so that
any  person  who  is  or  was a  director,  officer,  employee,  or  agent  of a
constituent  corporation,  or is or was serving at the request of a  constituent
corporation as a director,  officer,  employee, or agent of another corporation,
partnership,  joint venture, trust, or other enterprise, is in the same position
under this section with respect to the resulting or surviving  corporation as he
would  have  with  respect  to  such  constituent  corporation  if its  separate
existence had continued.

         (11) For purposes of this section;

              (a) The term "other enterprises" includes employee benefit plans;

              (b) The term "expenses" includes counsel fees, including those for
appeal;

              (c) The term "liability"  includes  obligations to pay a judgment,
settlement,  penalty, fine (including an excise tax assessed with respect to any
employee  benefit  plan),  and expenses  actually and  reasonably  incurred with
respect to a proceeding;

              (d) The term  "proceeding"  includes any threatened,  pending,  or
completed action,  suit, or other type of proceeding,  whether civil,  criminal,
administrative, or investigative and whether formal or informal;

              (e) The term "agent" includes a volunteer;

              (f) The term "serving at the request of the corporation"  includes
any service as a director,  officer,  employee, or agent of the corporation that
imposes duties on such persons, including duties relating to an employee benefit
plan and its participants or benefices; and

              (g) The term "not opposed to the best interest of the corporation"
describes  the  actions  of a person  who acts in good  faith and in a manner he
reasonably  believes  to be in  the  best  interests  of  the  participants  and
beneficiaries of an employee benefit plan.


                                        5
<PAGE>


         (12) A corporation shall have power to purchase and maintain  insurance
on behalf of any person who is or was a director, officer, employee, or agent of
the  corporation  or is or was  serving at the request of the  corporation  as a
director, officer, employee, or agent of another corporation, partnership, joint
venture,  trust or other enterprise  against any liability  asserted against him
and  incurred by him in any such  capacity or arising out of his status as such,
whether or not the  corporation  would have the power to  indemnify  him against
such liability under the provisions of this section.

         The Company  maintains an insurance  policy that  provides  protection,
within the maximum  liability  limits of the policy and subject to a  deductible
amount for each claim, to the Company under its indemnification  obligations and
to the  directors  and officers of the Company  with respect to certain  matters
that are not  covered  by the  Company's  indemnification  obligations.

ITEM 7.  EXEMPTION FROM REGISTRATION CLAIMED.
         -----------------------------------

         Not applicable.










                                        6
<PAGE>


ITEM 8.  EXHIBITS.
         --------


         EXHIBIT NO.       DESCRIPTION                     LOCATION
         -----------       -----------                     --------

            4.1            Genetic Vectors, Inc.           Provided herewith
                           1996 Incentive Plan

            4.2            Consulting Agreement,           Provided herewith
                           dated June 1996, by and
                           between the Company and
                           James A. Joyce

            5.1            Opinion of Kirkpatrick          Previously filed
                           & Lockhart LLP                  with Form S-8 on
                           re: legality                    May 28, 1998

            23.1           Consent of Kirkpatrick          Provided herewith
                           & Lockhart LLP

            23.2           Consent of BDO Seidman, LLP     Provided herewith

            24.1           Power of Attorney               Previously filed
                                                           with Form S-8 on
                                                           May 28, 1998


ITEM 9.  UNDERTAKINGS.
         ------------

(a)      The undersigned registrant will:

         (1)  File, during any period in which offers or sales are being made, a
         post-effective amendment to this Registration Statement to:

              (i)   Include any prospectus  required by Section  10(a)(3) of the
                    Act;

              (ii)  Reflect in the  prospectus any facts or events arising after
                    the  effective  date of the  Registration  Statement (or the
                    most  recent   post-effective   amendment   thereof)  which,
                    individually  or in the  aggregate,  represent a fundamental
                    change  in the  information  set  forth in the  Registration
                    Statement.  Notwithstanding  the foregoing,  any increase or
                    decrease  in  volume  of  securities  offered  (if the total
                    dollar  value of  securities  offered  would not exceed that
                    which was registered) and any deviation from the low or high
                    end of the estimated maximum offering range may be reflected
                    in the form of prospectus filed with the Commission pursuant
                    to Rule 424(b) if, in the  aggregate,  the changes in volume
                    and price represent no more than a 20% change in the maximum
                    aggregate  offering price set forth in the  "Calculation  of
                    Registration  Fee"  table  in  the  effective   registration
                    statement;

              (iii) Include any additional or changed material  information with
                    respect to the plan of distribution not previously disclosed
                    in the Registration Statement or any material change to such
                    information in the Registration Statement;

                  PROVIDED, HOWEVER, that paragraphs (a)(1)(i) and (a)(1)(ii) do
                  not apply if the Registration Statement is on Form S-3 or Form
                  S-8,  and  the  information  required  to  be  included  in  a
                  post-effective  amendment by those  paragraphs is contained in
                  periodic  reports filed by the registrant  pursuant to Section
                  13 or Section  15(d) of the  Securities  Exchange  Act of 1934
                  that  are   incorporated  by  reference  in  the  Registration
                  Statement.


                                        7
<PAGE>


         (2) For purposes of determining any liability under the Securities Act,
         treat each  post-effective  amendment as a new  registration  statement
         relating to the securities  offered  therein,  and the offering of such
         securities  at that time  shall be deemed to be the  initial  bona fide
         offering thereof.

         (3) File a post-effective  amendment to remove from registration any of
         the securities that remain unsold at the end of the offering.











                                        8
<PAGE>


                                   SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933, as amended,
the registrant certifies that it has reasonable grounds to believe that it meets
all of the  requirements  for  filing  on  Form  S-8 and has  duly  caused  this
Registration Statement to be signed on its behalf by the undersigned,  thereunto
duly  authorized,  in the City of  Miami,  State of  Florida  on this 8th day of
November, 2000.

                                  GENETIC VECTORS, INC.

                                  By: /s/ Mead M. McCabe, Jr.
                                     -------------------------------------------
                                     Printed Name:  Mead M. McCabe, Jr.
                                     Title:  Chief Executive Officer

         Pursuant  to the  requirements  of the  Securities  Act of  1933,  this
Registration  Statement  has  been  signed  by  the  following  persons  in  the
capacities  indicated,  which  together  constitute  a majority  of the board of
directors of the Company.

Date: November 8, 2000            By: /s/ Mead M. McCabe, Sr.
                                     -------------------------------------------
                                     Printed Name:  Mead M. McCabe, Sr., Ph.D.
                                     Title:  Chairman of the Board of Directors

Date: November 8, 2000            By: /s/ Mead M. McCabe, Jr.
                                     -------------------------------------------
                                     Printed Name:  Mead M. McCabe, Jr.
                                     Title:  Chief Executive Officer, Secretary,
                                             Chief Financial Officer
                                             and Director(Principal Financial
                                             and Accounting Officer)

Date: November 8, 2000            By: /s/ Jack Fell, Ph.D.
                                     -------------------------------------------
                                     Printed Name: Jack Fell, Ph.D.
                                     Title:  Director

Date: November 8, 2000            By: /s/ Mark E. Burroughs
                                     -------------------------------------------
                                     Printed Name: Mark E. Burroughs
                                     Title:  Director

Date: November 8, 2000            By: /s/ Michael C. Foley
                                     -------------------------------------------
                                     Printed Name: Michael C. Foley
                                     Title:  Director

Date: November 8, 2000            By: /s/ Eric Wilkinson
                                      ------------------------------------------
                                      Printed Name:  Eric Wilkinson
                                      Title:  Director


                                        9
<PAGE>


                                  EXHIBIT LIST
                                  ------------


         EXHIBIT NO.       DESCRIPTION                     LOCATION
         -----------       -----------                     --------

            4.1            Genetic Vectors, Inc.           Provided herewith
                           1996 Incentive Plan

            4.2            Consulting Agreement,           Provided herewith
                           dated June 1996, by and
                           between the Company and
                           James A. Joyce

            5.1            Opinion of Kirkpatrick          Previously filed
                           & Lockhart LLP                  with Form S-8 on
                           re: legality                    May 28, 1998

            23.1           Consent of Kirkpatrick          Provided herewith
                           & Lockhart LLP

            23.2           Consent of BDO Seidman, LLP     Provided herewith

            24.1           Power of Attorney               Previously filed
                                                           with Form S-8 on
                                                           May 28, 1998



                                       10



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