GENETIC VECTORS INC
S-8 POS, EX-4.2, 2000-11-08
PHARMACEUTICAL PREPARATIONS
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                                   EXHIBIT 4.2

                              CONSULTING AGREEMENT
                              --------------------

         THIS CONSULTING AGREEMENT (the "Agreement") is made and entered into on
June __, 1996, by and between GENETIC VECTORS,  INC., a Florida corporation (the
"Corporation"), and JAMES A. JOYCE (the "Consultant").

                                    RECITALS:
                                    --------

         WHEREAS,  the  Corporation  desires to engage the  Consultant,  and the
Consultant  desires to be engaged by the Corporation,  to provide the consulting
services   described   herein  upon  the  terms  and   conditions  and  for  the
consideration set forth in this Agreement.

         NOW,  THEREFORE,  in  consideration  of the  premises  and  the  mutual
covenants  and  agreements  contained  herein,  and for other good and  valuable
consideration,  the receipt and adequacy of which are hereby  acknowledged,  the
parties hereto, intending to be legally bound, hereby agree as follows:

         1.  SERVICES  TO  BE  PROVIDED.  The  Corporation  hereby  retains  the
Consultant  to perform  certain  business  consulting  services as  described on
Schedule "A" hereto.

         2.  COMPENSATION.  As  compensation  for his services,  the Corporation
shall pay the Consultant  $5,000.00 per month (the "Consulting  Fee") during the
term  hereof.  This  Consulting  Fee  shall  begin to accrue on the date of this
Agreement,  and all accrued Consulting Fees shall be payable ten (10) days after
the closing of the  Corporation's  proposed  private  placement bridge financing
transaction.  Thereafter,  the  Corporation  shall pay the Consulting Fee to the
Consultant by the fifteenth  (15th)  business day of each month for all services
to be performed in the succeeding month.

         3.  OPTIONS.  Subject to the  vesting  schedule  described  below,  the
Consultant  is hereby  granted  options (the  "Options")  to purchase a total of
75,000 shares of the  Corporation's  $0.10 par value per share common stock (the
"Common  Stock")  at an  exercise  price of $5.00  per  share.  One third of the
Options shall become  exercisable  upon the execution of this  Agreement by both
parties,  one third of the Options shall become  exercisable upon the closing of
an initial public offering of the Common Stock by the Corporation, and one third
of the  Options  shall  become  exercisable  if the  Corporation  enters into an
employment  relationship  (as  evidenced  by  the  execution  of  an  employment
agreement)  with  a  senior-level   officer  who  has  been  introduced  to  the
Corporation  by the  Consultant.  The  Options may be  exercised  by delivery of
written notice of such exercise to the  Corporation.  Notwithstanding  any other
provision of this  Agreement,  all  unexercised  Options shall  terminate on the
fourth anniversary of this Agreement.

         4.  DEVOTION OF TIME.  The Consultant shall devote  as much of his time
as reasonably required to perform his duties hereunder.

         5.  TERM; TERMINATION.  The term  of  this Agreement  shall commence on
the date hereof and shall terminate one hundred eighty (180) days after the date
hereof.  After  the  termination  of this 180 day  term,  this  Agreement  shall
continue  on a month to month  basis on the same  terms  and  conditions  as the
initial term,  and either party may then  terminate this Agreement at the end of
any  month by  written  notice  to the other  party.  Notwithstanding  any other
provision of this  Agreement,  if the  Corporation  (a) closes an initial public
offering  within six (6) months after the termination or expiration  hereof,  or

<PAGE>

(b) enters into an employment  relationship (as evidenced by the execution of an
employment  agreement)  within two (2) years after the expiration or termination
hereof with a senior-level  officer who was introduced to the Corporation by the
Consultant,  the  Consultant's  applicable  rights to  exercise  the  Options as
granted in Section 3 hereof shall survive the expiration or  termination  hereof
for such periods of time.

         6.  INDEPENDENT  CONTRACTOR.  The parties hereto  acknowledge and agree
that the  Consultant  is an  independent  contractor  and that  nothing  in this
Agreement  is intended to cause the  Consultant  to be an  employee,  fiduciary,
agent,  legal  representative,  partner or servant  of the  Corporation  for any
purpose whatsoever. The Corporation shall in no event assume liability for or be
deemed liable hereunder as a result of any contract,  agreement,  understanding,
debt or obligation  entered into by the Consultant on the  Corporation's  behalf
without the Corporation's prior written consent.

         7.  CONFIDENTIALITY.  By virtue  of the  services  performed hereunder,
the Consultant may obtain confidential or proprietary  information  belonging or
relating to the Corporation, regardless of whether any such information, data or
documents  qualify as "trade secrets" under  applicable law  (collectively,  the
"Confidential Information"). Because the secrecy of the Confidential Information
gives  the  Corporation  a  significant  competitive  business  advantage,   the
Consultant  agrees that he shall not  directly or  indirectly  disclose,  use or
cause or aid in the disclosure or use of any Confidential  Information during or
after the term of this  Agreement,  for whatever  reason,  except as required by
law,  with  the  prior  written  consent  of  the  Corporation,   or  when  such
Confidential  Information is otherwise  generally  available to the public.  The
Consultant  agrees that any violation or breach of any provision of this Section
7 will  cause  irreparable  harm to the  Corporation  and  cannot be  adequately
compensated for by money damages.  The Consultant therefore agrees that any such
violation  or breach  may be  enjoined  by any court of  competent  jurisdiction
without the posting of a bond,  without  waiving or affecting the  Corporation's
claims for money damages resulting from such violation or breach.

         8.  NONCOMPETITION  PROVISION.   During  the  term  of  this  Agreement
(including any monthly  extension of the initial term as contemplated in Section
5) and for ninety (90) days  thereafter,  the Consultant  shall not, except with
the prior  written  consent of the  Corporation,  which may be  withheld  in the
Corporation's sole discretion,  engage, as an employee, consultant, equity owner
or partner,  in any business activities anywhere in the world which are directly
competitive with those of the Corporation. Notwithstanding this restriction, the
Consultant  shall not be prohibited from engaging in any business  activities in
which his sole connection to such business  activities is the passive  ownership
of less than 10% of the outstanding equity interests of the entity involved, and
he may exceed  this 10%  ownership  threshold  with the  written  consent of the
Corporation.  This  provision  shall not affect the  Consultant's  ownership  or
service as an officer or  director of James Joyce &  Associates,  Inc.,  but the
Consultant's activities as a shareholder,  officer and director of James Joyce &
Associates, Inc. shall not be exempt from the provisions of this Section 8.

         9.  INDEMNIFICATION;  SURVIVAL. The Consultant shall indemnify and hold
the Corporation  harmless for any damages the Corporation  incurs as a result of
the Consultant's breach of Sections 6, 7 or 8 hereof. Sections 3, 6, 7, 8, 9, 13
and 14 hereof shall survive the  expiration or termination of this Agreement for
any reason.

         10. NOTICES.  Any notices given  under this  Agreement  shall be deemed
duly given if delivered in person or mailed by registered or certified  mail, if
to the Corporation to:


                                      -2-
<PAGE>

                                    Genetic Vectors, Inc.
                                    4181 Malaga Avenue
                                    Coconut Grove, Florida  33133
                                    Attn:  Mead McCabe, Jr., President


or if to the Consultant to:         James A. Joyce
                                    James Joyce & Associates, Inc.
                                    835 5th Avenue, Suite 202
                                    San Diego, California  92101


or to such other  address  as either  party may from time to time  designate  in
writing. The date of any such notice shall be deemed to be the date delivered in
person or the date so mailed.

         11. ENTIRE AGREEMENT;  AMENDMENT; GOVERNING LAW AND DISPUTE RESOLUTION.
This Agreement  contains the entire agreement  between the parties regarding the
matters   contained   herein,   and   supersedes   all  prior   agreements   and
understandings,  whether  oral  or  written,  between  the  Corporation  and the
Consultant.  This Agreement may not be amended or modified in any respect except
by a writing  executed by both of the parties  hereto.  This Agreement  shall be
governed by and construed  and  interpreted  in accordance  with the laws of the
State of Florida.  Any dispute or  controversy  which arises between the parties
hereto in  connection  with this  Agreement  shall be  conclusively  resolved by
binding  arbitration  (by an arbitrator  mutually  agreeable to both parties) in
accordance  with the Commercial  Arbitration  Rules of the American  Arbitration
Association then in effect unless the parties hereto otherwise mutually agree in
writing.  Such arbitration shall take place in Miami,  Florida.  The judgment of
the  arbitrator  or  arbitrators  shall be final and  binding on the parties and
judgment  upon the  arbitration  award may be entered in any court of  competent
jurisdiction.  The arbitrator or arbitrators shall determine the allocation,  if
any,  of  all  costs  and  expenses  of  such  arbitration,  including,  without
limitation, attorneys' fees.

         12. EXPENSES.   Upon   the    submission  of   appropriate   supporting
documentation, the Corporation shall reimburse the Consultant for all reasonable
expenses  incurred  by him in  connection  with the  provision  of his  services
hereunder; provided, however, that the Consultant shall obtain the Corporation's
prior written  approval,  which may be withheld in its sole discretion,  for any
expenses which exceed an aggregate of $500.00 during any month.

         13. PIGGYBACK REGISTRATION RIGHTS.

                        a. NOTICE REQUIREMENT.  If at any time during the period
(the  "Registration  Rights Period")  beginning on the first  anniversary of the
date of this  Agreement and ending on the fifth  anniversary of the date of this
Agreement  the  Corporation  proposes to register  any shares (the  "Shares") of
Common Stock under the  Securities  Act of 1933 (as  amended) or any  applicable
state  securities laws  (collectively  referred to as the "Securities  Laws") in
connection with an offering (an "Offering") of the Common Stock, the Corporation
shall deliver to the Consultant  notice of its intention to register such Shares
(the  "Registration  Notice") at least thirty (30) days prior to any filing of a
registration statement.

                        b. REGISTRATION  OBLIGATION.  If the Consultant delivers
written notice of his intent to exercise his  registration  rights  hereunder to
the Corporation no later than thirty (30) days after the Consultant receives the


                                      -3-
<PAGE>

Registration  Notice, the Corporation shall, subject to the terms and conditions
of this Section 13, use its best efforts to register under the  Securities  Laws
the number of Shares that the Consultant requests by inclusion of such Shares in
the  applicable   registration   statement.   The  Consultant's  notice  to  the
Corporation shall include the number of Shares that he intends to register along
with any other  information that the Corporation may request in the Registration
Notice.

                        c. REGISTRATION  EXPENSES. The Corporation shall pay all
expenses related to each registration of Shares hereunder.

                        d.  EXCLUSIONS  FROM   REGISTRATION   OBLIGATIONS.   The
Corporation  shall not be obligated to register any of the  Consultant's  Shares
pursuant to this  Section 13 if (i) in the judgment of the lead  underwriter  or
underwriters (collectively,  the "Underwriters") for an Offering, such inclusion
of the Consultant's  Shares in that Offering would jeopardize the success of the
Offering,  (ii) the  Consultant  does not provide the  information  described in
Sections 13(b) or 13(e) hereof in a timely manner, or (iii) an Offering is to be
effected on a form that is not appropriate for the inclusion of the Consultant's
Shares.

                        e. INFORMATION;  INDEMNIFICATION. In connection with any
registrations  of Shares  hereunder,  the Consultant  shall promptly provide all
information  requested by the  Corporation.  The Consultant  shall indemnify and
hold the Corporation and the Underwriters harmless for any liability that any of
them  suffers  as  a  result  of  (i)  erroneous  information  supplied  by  the
Consultant, or (ii) the omission of any information by the Consultant.

                        f. MISCELLANEOUS.  The Consultant shall have no right to
dictate  any of the terms or  conditions  of any  Offering,  including,  without
limitation,  the  acceleration  or  delay of the  timing  of the  Offering,  the
jurisdictions  in which the  Offering  will be made or the  price of the  Shares
offered  thereby.  All of these terms and conditions  shall be determined by the
Corporation and the  Underwriters.  The Consultant  agrees and acknowledges that
the Corporation is under no obligation to, and makes no  representation  that it
will,   effect  any   Offerings   during   the   Registration   Rights   Period.
Notwithstanding any other provision of this Agreement, the Consultant shall only
be  entitled  to  participate  in a  total  of  two  (2)  Offerings  during  the
Registration Rights Period.

         14. REGISTRATION ON FORM S-8.  Except as otherwise provided herein, the
Consultant shall be entitled to have his Options  registered on any registration
statement on Securities  and Exchange  Commission  Form S-8 ("Form S-8") that is
filed by the Company within the five (5) year period  following the date of this
Agreement.  The rights  granted in this Section 14 shall not be available to the
Consultant  if, in the Company's  reasonable  discretion,  the Consultant is not
eligible to utilize Form S-8 under  applicable  SEC rules.  The Company makes no
representation  or guarantee to the  Consultant  that he will be eligible to use
Form  S-8.  The  Company  shall  use its  best  efforts  to have a  registration
statement on Form S-8 in place on or before the second  anniversary  of the date
hereof.

         15. SEVERABILITY.  If any  provision  of  this  Agreement is held to be
invalid, illegal or unenforceable in any respect, such invalidity, illegality or
unenforceability  shall not affect any other provision hereof and all such other
provisions shall remain in full force and effect.

         16. ASSIGNMENT. This Agreement is personal in nature and the Consultant
shall  not  assign or  transfer  this  Agreement  or any  rights or  obligations
hereunder without the prior written consent of the Corporation.


                                      -4-
<PAGE>

         17. WAIVER.  The failure of either party hereto at any time or times to
require  performance  hereunder  shall in no way affect such party's  right at a
later  time to  require  such  performance.  No waiver  by  either  party of any
condition,  or of the  breach  of any  term  contained  herein,  by  conduct  or
otherwise, in any one or more instances, shall be deemed to be or construed as a
further  or  continuing  waiver of such  condition  or breach or a waiver of any
other condition or breach of any other term of this Agreement.

         IN WITNESS WHEREOF, the parties have executed this Consulting Agreement
as of the date first above written.


                                   GENETIC VECTORS, INC.


                                   By: /s/ Mead M. McCabe, Jr.
                                      ------------------------
                                           Mead M. McCabe, Jr.

                                   Its: President
                                        ----------------------


                                   /s/ James A. Joyce
                                   ---------------------------
                                       James A. Joyce


<PAGE>


                                   EXHIBIT "A"
                                   -----------

                       DESCRIPTION OF CONSULTING SERVICES
                       ----------------------------------

         General management consulting services,  including, without limitation,
business development, corporate planning and employee recruitment.



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