PATIENT INFOSYSTEMS INC
10-Q, 2000-11-20
MISC HEALTH & ALLIED SERVICES, NEC
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                              Washington D.C. 20549

                                    FORM 10Q



[ X ]    QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15 (d) OF
         THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended:             September 30, 2000
                                 ------------------------------------


                                       OR

[    ]   TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF
         THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from                       to
                               --------------------------------------

Commission file number:                          0-22319
                         --------------------------------------------
                            PATIENT INFOSYSTEMS, INC.
               (Exact name of registrant as specified in its charter)

          Delaware                                   16-1476509
          --------                                   ----------
(State or other jurisdiction of           (I.R.S. Employer Identification No.)
incorporation or organization)

                      46 Prince Street, Rochester, NY 14607
                    (Address of principal executive offices)
                                   (Zip Code)

                                 (716) 242-7200
              (Registrant's telephone number, including area code)


         Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15 (d) of the  Securities  Exchange Act of
1934  during  the  preceding  12 months  (or for such  shorter  period  that the
registrant was required to file such reports),  and (2) has been subject to such
filing requirements for the last 90 days. Yes [X] No [ ]

         As of November 13, 2000, 8,220,202 common shares were outstanding.



<PAGE>
PART I. FINANCIAL INFORMATION
Item 1. Condensed Financial Statements

<TABLE>
<CAPTION>
PATIENT INFOSYSTEMS, INC.

CNDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED)
---------------------------------------------------------------------------------------------------------------------------------

ASSETS                                                                        September 30, 2000          December 31, 1999
                                                                              ------------------          -----------------
CURRENT ASSETS:
<S>                                                                           <C>                        <C>
  Cash and cash equivalents                                                    $      127,791             $      489,521
  Accounts receivable                                                                 407,941                    650,279
  Prepaid expenses and other current assets                                           131,323                    202,064
                                                                          -------------------------------------------------------
        Total current assets                                                          667,055                  1,341,864

PROPERTY AND EQUIPMENT, net                                                           926,866                  1,291,351

Debt issuance costs (net of accumulated amortization of $472,000 and $0)              385,500                    382,500
Intangible assets (net of accumulated amortization of $120,220 and
$38,055)                                                                              502,503                    584,669
Other assets                                                                          200,000                    244,011
                                                                          -------------------------------------------------------
TOTAL ASSETS                                                                   $    2,681,924             $    3,844,395
                                                                          =======================================================
LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIT)

CURRENT LIABILITIES:
  Accounts payable                                                             $      228,893             $      496,533
  Accrued salaries and wages                                                          217,191                    190,232
  Borrowings from directors                                                           375,000                       -
  Line of credit                                                                    2,500,000                       -
  Accrued expenses                                                                    104,429                     22,767
  Deferred revenue                                                                    157,731                    218,200
                                                                          -------------------------------------------------------
        Total current liabilities                                              $    3,583,244             $      927,732
                                                                          -------------------------------------------------------
LINE OF CREDIT                                                                           -                       500,000

STOCKHOLDERS' EQUITY (DEFICIT):
  Common stock - $.01 par value:  shares authorized:
      20,000,000; issued and outstanding: September 30,
     2000 - 8,220,202; December 31, 1999 - 8,040,202                                   82,202                     80,402
  Preferred stock - $.01 par value:  shares authorized: 5,000,000
    Series C, 9% cumulative, convertible
      issued and outstanding September 30, 2000 - 100,000                               1,000                       -
  Additional paid-in capital                                                       24,016,798                 21,968,536
  Accumulated other comprehensive income                                                1,805                      1,805
  Accumulated deficit                                                             (25,003,125)               (19,634,080)
                                                                          -------------------------------------------------------
        Total stockholders' equity (deficit)                                   $     (901,320)            $    2,416,663
                                                                          -------------------------------------------------------
TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIT)                           $    2,681,924             $    3,844,395
                                                                          =======================================================

See notes to unadudited condensed consolidated financial statements.
</TABLE>
<PAGE>
<TABLE>
<CAPTION>
PATIENT INFOSYSTEMS, INC.

CONSOLIDATED STATEMENTS OF OPERATIONS (UNAUDITED)
----------------------------------------------------------------------------------------------------------------------------

                                                         Three Months Ended                     Nine Months Ended
                                                           September 30,                          September 30,
                                                      2000               1999                2000               1999
                                                      ----               ----                ----               ----

<S>                                            <C>               <C>                <C>                <C>
REVENUES
  Operations Fees                              $     385,304      $     845,964      $    1,517,598     $    2,682,720
  Development Fees                                    13,246               -                 34,446               -
  Licensing Fees                                      35,000             30,000              80,826             30,000
                                               -----------------------------------------------------------------------------
       Total revenues                                433,550            875,964           1,632,870          2,712,720
                                               -----------------------------------------------------------------------------

COSTS AND EXPENSES
  Cost of sales                                      982,638          1,447,869           3,466,670          4,162,140
  Sales and marketing                                234,942            626,725             816,965          1,921,364
  General and administrative                         590,073            422,124           1,743,360          1,381,205
  Research and development                            73,997            284,838             237,196            712,285
                                               -----------------------------------------------------------------------------
        Total costs and expenses                   1,881,650          2,781,556           6,264,191          8,176,994
                                               -----------------------------------------------------------------------------
OPERATING LOSS                                    (1,448,100)        (1,905,592)         (4,631,321)        (5,464,274)

Investment loss                                         -                (7,697)               -              (335,202)
Other income (expense)                               (62,667)            30,754            (142,723)           160,326
                                               -----------------------------------------------------------------------------
NET LOSS                                          (1,510,767)        (1,882,535)         (4,774,044)        (5,639,150)

CONVERTIBLE PREFERRED STOCK DIVIDENDS                (22,500)              -               (595,000)              -
                                               -----------------------------------------------------------------------------
NET LOSS ATTRIBUTABLE TO COMMON SHAREHOLDERS   $  (1,533,267)     $  (1,882,535)     $   (5,369,044)    $   (5,639,150)
                                               =============================================================================
NET LOSS PER SHARE - BASIC AND DILUTED         $       (0.19)     $       (0.23)     $        (0.66)    $        (0.70)
                                               =============================================================================
WEIGHTED AVERAGE COMMON SHARES                     8,209,040          8,033,400           8,106,779          8,030,003
                                               =============================================================================

See notes to unadudited condensed consolidated financial statements.
</TABLE>
<PAGE>
<TABLE>
<CAPTION>
PATIENT INFOSYSTEMS, INC.

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED)
-------------------------------------------------------------------------------------------------------------------------

                                                                               Nine Months             Nine Months
                                                                                  Ended                   Ended
                                                                            September 30, 2000     September 30, 1999

<S>                                                                      <C>                     <C>
OPERATING ACTIVITIES:
  Net loss                                                                $     (4,774,044)       $     (5,639,150)
  Adjustments to reconcile net loss to net cash used in
    operating activities:
      Depreciation and amortization                                                896,544                 374,130
      Loss on disposal of fixed assets                                              21,842                 335,202
      Loss on investments                                                             -                    (58,935)
      Compensation expense related to issuance of stock warrants                     1,042                    -
      Decrease in accounts receivable, net                                         242,338                  10,830
      Decrease in prepaid expenses and other current assets                         70,741                  17,740
      Decrease (Increase) in other assets                                           44,011                  (3,994)
      (Decrease) Increase in accounts payable                                     (267,640)                157,716
      Increase in accrued salaries and wages                                        26,959                  11,621
      Increase (Decrease) in accrued expenses                                       36,662                 (35,700)
      Decrease in deferred revenue                                                 (60,469)                (10,960)
                                                                                -----------             -----------
            Net cash used in operating activities                               (3,762,014)             (4,841,500)
                                                                                -----------             -----------

INVESTING ACTIVITIES:
  Property and equipment additions                                                 (17,976)               (550,807)
  Proceeds from sale of fixed assests                                               18,240                    -
  Purchases of available-for-sale  securities                                         -                    (21,073)
  Maturities of available-for-sale securities                                         -                  1,050,747
  Purchase of HealthDesk Intellectual Property, net                                   -                   (595,048)
                                                                                -----------             -----------
          Net cash provided by (used in) investing activities                          264                (116,181)
                                                                                -----------             -----------

FINANCING ACTIVITIES:
  Proceeds from issuance of common and preferred stock, net                      1,025,020                  18,576
  Borrowings from directors                                                        375,000                    -
  Line of credit borrowings                                                      2,000,000                    -
                                                                                -----------             -----------
           Net cash provided by financing activities                             3,400,020                  18,576
                                                                                -----------             -----------

NET DECREASE IN CASH AND CASH  EQUIVALENTS                                         188,270              (4,939,105)

CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD                                   489,521               6,316,955
                                                                                -----------             -----------

CASH AND CASH EQUIVALENTS AT END OF PERIOD                                $        127,791        $      1,377,850
                                                                          =================       =================
Supplemental disclosures of cash flow information
   Cash paid and received for income taxes, net                           $           -           $         32,041
                                                                          =================       =================

Supplemental  disclosures of non-cash  information
  Fair value of stock purchase warrants issued in conjunction with
    guarantees by certain board members of borrowings on the line
    of credit                                                             $        475,000        $           -
                                                                          =================       =================
  Dividends declared on Class C Convertible Preferred Stock               $         45,000        $           -
                                                                          =================       =================
  Value of beneficial conversion feature on Class C Convertible
    Preferred Stock recognized as a dividend                              $        550,000        $           -
                                                                          =================       =================

See notes to unadudited condensed consolidated financial statements.
</TABLE>
<PAGE>
PATIENT INFOSYSTEMS, INC.


Notes to Consolidated Financial Statements

1.   The unadudited  condensed  consolidated  financial statements for the three
     and nine-month periods ended  September 30, 2000 and September 30, 1999 are
     unaudited and reflect all adjustments  (consisting only of normal recurring
     adjustments) which are, in the opinion of management,  necessary for a fair
     presentation  of the  financial  position  and  operating  results  for the
     interim  periods.  Certain prior period amounts have been  reclassified  to
     conform  to  current  period   presentations.   The  unadudited   condensed
     consolidated  financial  statements  and  notes  thereto  should be read in
     conjunction  with the  Company's  Annual  Report  on Form 10-K for the year
     ended  December  31,  1999.  The  results of  operations  for the three and
     nine-month periods ended September 30, 2000 are not necessarily  indicative
     of the results for the entire year ending December 31, 2000.

2.   Intangible  assets represent the intellectual  property (i.e.:  tradenames,
     trademarks,  licenses and brandnames) acquired from HealthDesk Corporation.
     Until March 31, 2000,  this asset was being  amortized  over 15 years using
     the  straight-line  method.  As a result  of a further  evaluation  of this
     asset,  it has been decided to alter the  amortization  based upon having a
     remaining  life of 4 years  starting  April 1, 2000  using a  straight-line
     method. The net asset value for this intellectual  property was $502,503 at
     September 30, 2000 and reflects the change in amortization  effective April
     1, 2000.

3.   On March 31,  2000,  the Company  completed a private  placement of 100,000
     shares of newly issued Series C 9% Cumulative  Convertible  Preferred Stock
     ("Series C"),  raising  $1,000,000 in total  proceeds.  These shares can be
     converted  into  Common  Stock at a rate of 8 shares of  Common  Stock to 1
     share of Series C Preferred  Stock.  Each Series C share has voting  rights
     equivalent to 8 shares of Common Stock (800,000 shares).  The proceeds from
     this issuance have been used to support the Company's operations.

     The fair market value of the Company's Common Stock at the time of issuance
     of Series C Preferred Stock was $1.9375 per share.  The Series C Shares are
     convertible  at a price equal to $1.25 per share of Common Stock  resulting
     in a discount,  or beneficial conversion feature, of $0.6875 per share. The
     incremental  fair  value of  $550,000  for the  100,000  shares of Series C
     Preferred  issued is  deemed  to be the  equivalent  of a  preferred  stock
     dividend.  The Company recorded the deemed dividend at the date of issuance
     by  offsetting  charges  and  credits  to  additional  paid in  capital  of
     $550,000,  without  any effect on total  stockholders'  equity.  The amount
     increased the loss applicable to common  stockholders in the calculation of
     basic  net loss per  share  for the  three  and  nine-month  periods  ended
     September 30, 2000.  Form 10-Q/A  amendments to the Company's three and six
     month  periods  ended March 31, 2000 and June 30,  2000  respectively  were
     filed  simultaneously  with this Form 10-Q to  reflect  the  adjustment  to
     paid-in capital, reclassifications consistent with current presentation and
     net less per share for such periods.  No  adjustment  was made to any other
     information in such filings.

4.   In December 1999, the Company  established a credit facility for $1,500,000
     guaranteed by Derace Schaffer and John Pappajohn, directors of the Company.
     In consideration for their guarantees,  the Company granted to Dr. Schaffer
     and Mr.  Pappajohn  warrants to purchase an aggregate of 375,000  shares of
     common  stock for  $1.5625  per share.  In March  2000,  the  facility  was
     increased by $1,000,000 under substantially the same terms, also guaranteed
     by the same Board  members.  Because this line of credit is due and payable
     on March 31, 2001,  amounts  outstanding at September 30, 2000 and December
     31, 1999 are reported as current and long-term  liabilities,  respectively.
     Additional  warrants to purchase an aggregate  of 250,000  shares of Common
     Stock for $2.325 per share,  were  granted to Dr.  Derace  Schaffer and Mr.
     John Pappajohn for their guarantee of this  additional line of credit.  The
     warrants are included in the debt issuance costs in the balance sheet.  The
     estimated fair value of the warrants at September 30, 2000 is approximately
     $857,500 based on the application of the Black Scholes option pricing model
     which  incorporates  current stock price,  expected stock price volatility,
     expected interest rates, and the expected holding period of the warrant.

     In August 2000,  the Company  borrowed  $125,000  and in September  2000 an
     additional $62,500 from Mr. John Pappajohn.  Proceeds from these loans were
     used to support the  Company's  operations.  The interest on these loans is
     9.5% per year.

     In August 2000,  the Company  borrowed  $125,000  and in September  2000 an
     additional $62,500 from Dr. Derace Schaffer. Proceeds from these loans were
     used to support the  Company's  operations.  The interest on these loans is
     9.5% per year.

     The loans from Mr. Pappajohn and Dr. Schaffer are demand Notes and intended
     to be secured by the assets of The Company.

5.   The  calculations  for the basic and diluted loss per share were based upon
     loss attributable to common  stockholders of $1,533,267 and $1,882,535 with
     a weighted  average  number of common shares of 8,209,040 and 8,033,400 for
     the three-month  periods ended September 30, 2000 and 1999 respectively and
     $5,369,044 and $5,639,150  with a weighted  average number of common shares
     of 8,106,779 and 8,030,003 for the nine-month  periods ended  September 30,
     2000 and 1999  respectively.  Options and  warrants  to purchase  shares of
     Common  Stock were  outstanding  but not  included  in the  computation  of
     diluted loss per share for the three and  six-month  periods ended June 30,
     2000 and 1999  because the effect would have been  antidilutive  due to the
     net loss in those periods.

6.   In June 1998, the Financial  Accounting  Standards  Board  ("FASB")  issued
     Statement of Financial  Accounting  Standards ("SFAS") No. 133, "Accounting
     for Derivative Instruments and Hedging Activities".  In June 2000, the FASB
     issued SFAS No. 138, which amends certain provisions of SFAS 133 to clarify
     four areas causing  difficulties in implementation.  The amendment included
     expanding  the normal  purchase and sale  exemption  for supply  contracts,
     permitting  the  offsetting  of  certain   intercompany   foreign  currency
     derivatives  and thus  reducing  the  number  of third  party  derivatives,
     permitting hedge  accounting for  foreign-currency  denominated  assets and
     liabilities,  and  redefining  interest  rate  risk to  reduce  sources  of
     ineffectiveness. We have appointed a team to implement SFAS 133 on a global
     basis  for the  Company.  This  team  has  been  implementing  an SFAS  133
     compliant  risk  management  information  system,  globally  educating both
     financial and non-financial  personnel,  inventorying  embedded derivatives
     and addressing  various other SFAS 133 related  issues.  We will adopt SFAS
     133 and the  corresponding  amendments  under  SFAS 138 on January 1, 2001.
     SFAS 133, as amended by SFAS 138, is not expected to have a material impact
     on the Company's  condensed  consolidated  financial  position,  results of
     operations or cash flows.

     In September 2000, the Financial Accounting Standards Board issued SFAS No.
     140,  "Accounting  for  Transfers  and  Servicing of  Financial  Assets and
     Extinguishment of Liabilities," which supercedes SFAS No. 125,  "Accounting
     for  Transfers  and Servicing of Financial  Assets and  Extinguishments  of
     Liabilities."  This  standard is effective for  transfers  occurring  after
     March 31, 2001, with certain disclosure requirements effective for the year
     ending December 31, 2000. The Company does not believe the adoption of this
     standard  will  have  a  significant  impact  on  the  Company's  condensed
     consolidated financial position, results of operations or cash flows.

     In December 1999, the Securities and Exchange Commission (SEC) issued Staff
     Accounting  Bulletin No. 101 (SAB 101),  "Revenue  Recognition in Financial
     Statements,"  which provides guidance on the recognition,  presentation and
     disclosure of revenue in financial  statements filed with the SEC. SAB 101,
     as  amended,  is  required  to be adopted by the  Company no later than the
     fourth  quarter of fiscal  year 2000.  Although  the  Company has not fully
     assessed  the  implications  of SAB 101,  management  does not  believe the
     adoption  of SAB  101  will  have a  significant  impact  on the  Company's
     condensed  consolidated  financial position,  results of operations or cash
     flows.


7.   The accompanying unaudited condensed consolidated financial statements have
     been prepared on a going concern basis,  which contemplates the realization
     of assets and the  satisfaction  of  liabilities  in the  normal  course of
     business.  As shown in the accompanying  unaudited  condensed  consolidated
     financial  statements,  the  Company  incurred  an  operating  loss for the
     nine-month  period  ended  September  30,  2000  of  $4,631,321  and had an
     accumulated  deficit of  $19,634,080  at December 31, 1999.  These factors,
     among others may indicate  that the Company will be unable to continue as a
     going concern for a reasonable period of time.

     The unaudited condensed  consolidated  financial  statements do not include
     any adjustments relating to the recoverability of assets and classification
     of  liabilities  that might be  necessary  should the  Company be unable to
     continue as a going concern. The Company's  continuation as a going concern
     is dependant upon its ability to generate  sufficient cash flow to meet its
     obligations.  Management is currently  assessing  the  Company's  operating
     structure for the purpose of reducing ongoing expenses,  increasing sources
     of  revenue  and is  negotiating  the  terms of  additional  debt or equity
     financing.

8.   Subsequent  Event - In October 2000, the Company  borrowed  $125,000 and in
     November 2000 an additional $25,000 from Mr. John Pappajohn.  Proceeds from
     these  demand  loans were used to support  the  Company's  operations.  The
     interest on these loans is 9.5% per year.

     In October 2000, the Company  borrowed  $125,000 from Dr. Derace  Schaffer.
     Proceeds  from  these  demand  loans  were used to  support  the  Company's
     operations. The interest on these loans is 9.5% per year.

     The Company anticipates that it will need to borrow additional funds before
     it can  secure  additional  capital  through  the  issuance  of  additional
     securities.  The Company's current directors have no obligation to continue
     to provide  funds  There can be no  assurances  given that the  company can
     borrow  the  additional  amounts  needed  or  that  the  Company  can  sell
     additional securities.


<PAGE>


Item 2.  Management's Discussion and Analysis of Financial Condition and Results
         of Operations.

     Management's  discussion  and analysis  provides a review of the  Company's
operating  results for the three and nine month periods ended September 30, 2000
and September 30, 1999 and its  financial  condition at September 30, 2000.  The
focus of this  review is on the  underlying  business  reasons  for  significant
changes and trends affecting the revenues,  net earnings and financial condition
of the Company.  This review should be read in conjunction with the accompanying
unaudited condensed consolidated financial statements.

     In an effort to give investors a well-rounded view of the Company's current
condition and future opportunities,  this Quarterly Report on Form 10-Q includes
forecasts by the  Company's  management  about future  performance  and results.
Because they are forward-looking,  these forecasts involve uncertainties.  These
uncertainties include the Company's working capital shortfalls,  risks of market
acceptance of or preference for the Company's systems and services,  competitive
forces, the impact of, and changes in, government regulations,  general economic
factors in the healthcare  industry and other factors discussed in the Company's
filings with the  Securities  and Exchange  Commission  including  the Company's
Annual Report on Form 10-K for the year ended December 31, 1999.

Results of Operations

     Revenues

     Revenues  consist of revenues from  operations,  development  and licensing
fees.  Revenues  decreased from $875,964 during the three months ended September
30, 1999 to $433,550  during the three months ended  September 30, 2000, or 51%.
Revenues  decreased from  $2,712,720  during the nine months ended September 30,
1999 to $1,632,870 during the nine months ended September 30, 2000, or 40%.


<TABLE>
<CAPTION>
                                                      Three Months Ended                          Nine Months Ended
                                                         September 30,                              September 30,
Revenues                                              2000           1999                        2000           1999
--------                                              ----           ----                        ----           ----
<S>                                              <C>            <C>                         <C>            <C>
Operations Fees
  Disease Management and Compliance               $ 164,935      $ 319,787                   $ 493,559      $ 875,240
  Surveys                                            54,089        286,236                     315,976      1,067,411
  Demand Management                                 146,603        205,424                     619,859        597,427
  Other                                              19,677         34,517                      88,204        142,642
                                              ------------------------------            -------------------------------
Total Operations Fees                               385,304        845,964                   1,517,598      2,682,720
Development Fees                                     13,246           -                         34,446           -
Licensing Fees                                       35,000         30,000                      80,826         30,000
                                              ------------------------------            -------------------------------
Total Revenues                                    $ 433,550      $ 875,964                  $1,632,870      $2,712,720
                                              ------------------------------            -------------------------------
</TABLE>


     Operations  revenues are generated as the Company provides  services to its
customers.  Operations  revenues decreased from $845,964 during the three months
ended September 30, 1999 to $385,304 during the three months ended September 30,
2000. Operations revenues decreased from $2,682,720 during the nine months ended
September  30, 1999 to  $1,517,598  during the nine months ended  September  30,
2000.  Operations  revenues continue to be the primary source of revenue for the
Company.  Operations  revenues  declined  because the Company had fewer projects
after two of the Company's primary customers  eliminated  products for which the
Company  provided  services  and a major  pharmaceutical  client  completed  two
initiatives. These clients have not provided the Company with new assignments to
replace the completed  projects.  Demand Management  revenues increased over the
nine-month period due to increases in the membership of the existing clients and
the addition of a new customer.  Demand Management  revenues  decreased over the
three-month period ended September 30, 2000 due to the elimination of a Medicaid
product by one of the Company's customers. The Company continues to provide this
customer with Demand Management services for it's commercial product.

     Development  revenue  represents  the amounts that the Company  charges its
customers for the development of its customized programs. There were $13,246 and
$34,446  of  development  revenues  in the three and  nine-month  periods  ended
September 30, 2000  respectively.  The Company has entered into new  development
agreements but  anticipates  that revenue from program  development  will remain
immaterial in the future.

     License revenues recognized from the Case Management Support System for the
three and  nine-month  period ended  September 30, 2000 were $35,000 and $80,826
respectively.  The Company has not entered into any new licensing agreements for
its Case  Management  Support  System and the  revenue  for the  current  period
reflects ongoing revenue from the existing agreements.

     Costs and Expenses

     Cost of sales include salaries and related  benefits,  services provided by
third  parties,  and  other  expenses  associated  with the  implementation  and
delivery of the  Company's  standard  and  customized  population,  demand,  and
disease management programs.  Cost of sales for the three months ended September
30, 2000 was $982,638 as compared to $1,447,869 for the three-month period ended
September 30, 1999. For the nine months ended  September 30, 2000, cost of sales
was  $3,466,670,  as compared to $4,162,140 for the nine months ended  September
30,  1999.  The  decrease  in these costs  primarily  reflects a response to the
decreased level of population and disease management  operational activities and
other cost  reductions  undertaken  by the Company's  management.  The Company's
gross margin continues to be negative. The Company anticipates that revenue must
substantially  increase before it will begin to recognize economies of scale. No
assurance  can be given that  revenues  will  increase or that, if they do, they
will exceed expenses.

     Sales  and  marketing  expenses  consist  primarily  of  salaries,  related
benefits,  travel costs,  sales materials and other marketing  related expenses.
Sales and marketing  expenses for the three months ended September 30, 2000 were
$234,942 as compared to $626,725 for the three-month  period ended September 30,
1999. For the nine months ended September 30, 2000, sales and marketing expenses
were $816,965, as compared to $1,921,364 for the nine months ended September 30,
1999.  Spending in this area has decreased due to the resignation or termination
of several members of the sales staff. The Company anticipates  expansion of the
Company's sales and marketing staff and, if funds become available, that it will
continue to invest in the sales and marketing process in future periods.

     General  and  administrative   expenses  include  the  costs  of  corporate
operations,  finance and accounting, human resources and other general operating
expenses of the  Company.  General  and  administrative  expenses  for the three
months ended  September 30, 2000 were $590,073,  as compared to $422,124 for the
three-month period ended September 30, 1999. For the nine months ended September
30, 2000,  general and  administrative  expense was  $1,743,360,  as compared to
$1,381,205 for the nine months ended September 30, 1999. These expenditures have
been  incurred to maintain  the  corporate  infrastructure  necessary to support
anticipated  program  operations.  The  increase  in  these  costs  was  due  to
amortization  of  $857,500  in debt  issuance  cost for the  establishment  of a
$2,500,000  line of  credit.  This cost is a non-cash  item  related to the fair
market  value of warrants to purchase the  Company's  common  stock,  which were
issued to two directors in  consideration  for their  guarantee of the debt. The
amortization  expense  recorded  was  $192,750  and  $472,000  for the three and
nine-month periods ended September 30, 2000. Without this amortization,  general
and  administrative  expenses decreased to $397,323 and $1,271,360 for the three
and nine-month  periods ended  September 30, 2000.  This full impact of the cost
reduction efforts was only partially  reflected in these costs due to a one-time
write-off  of $87,685 in trade  receivables  during the nine month  period ended
September 30, 2000,  which is no longer  considered  collectable.  When the debt
issuance  costs are  fully  amortized,  the  Company  expects  the  General  and
Administrative costs to remain relatively constant in future periods.

     Research and development expenses consist primarily of salaries and related
benefits and  administrative  costs  associated  with the development of certain
components of the Company's integrated  information capture and delivery system,
the  Company's  standardized  disease  management  programs  and  the  Company's
Internet based technology  products.  Research and development  expenses for the
three months ended September 30, 2000 were $73,997,  as compared to $284,838 for
the three months ended  September 30, 1999. For the nine months ended  September
30, 2000,  research  and  development  expenses  were  $237,196,  as compared to
$712,285 for the nine months ended September 30, 1999. This reduction reflects a
shift in technology staffing to support existing operations rather than research
and development  activities.  It is anticipated  that as the Company evolves its
technology  infrastructure,  that modest  increases in research and  development
expense will be required.

     The  Company  recorded  no  investment  loss  for the  three  months  ended
September  30, 2000 as compared to a loss of $7,697 for the  three-month  period
ended  September 30, 1999.  There was no  investment  loss recorded for the nine
months  ended  September  30, 2000 as  compared to $335,202  for the nine months
ended  September 30, 1999. In 1999, the Company's  investment  loss included its
investment in Patient  Infosystems Canada, Inc. and a one-time write-off of it's
investment in the Pulse Group.

     The Company  recorded a loss of $62,667 and $142,723 in other  expenses for
the three and  nine-month  periods  ended  September 30, 2000  respectively,  as
compared to a gain of $30,754 and $160,326 for the three and nine-month  periods
ended September 30, 1999 respectively The Company generates interest income from
cash  balances  and  investments  and pays  interest on debt.  The net  interest
expense  recorded was $58,080 and $121,580 for the three and nine-month  periods
ended  September  30, 2000 as compared to a net gain of $30,754 and $160,326 for
the same periods of 1999 due to the  reduction of cash for which the Company was
paid interest and the increase of interest  expenses on debt. The balance of the
loss of $4,587 and $21,143 for the three and nine-month periods ending September
30, 2000 primarily  relate to a loss on the sale or abandonment of certain fixed
assets.

     The Company had a net loss  attributable to the Common  shareholders  after
preferred stock dividends of $1,533,267 for the three months ended September 30,
2000,  as  compared  to a net loss of  $1,882,535  for the  three  months  ended
September 30, 1999.  This represents a net loss per share of $0.19 for the third
quarter  of 2000,  as  compared  to a net loss of $0.23  per  share in the third
quarter  of 1999.  The net loss  attributable  to  Common  shareholders  for the
nine-month  period  ended  September  30,  2000 is  $5,369,044  as  compared  to
$5,639,150 for the same period of 1999.  This represents a net loss per share of
$0.66 for the first three  quarters of 2000,  as compared to a net loss of $0.70
per share in the first three  quarters of 1999.  The preferred  stock  dividends
include accrued dividends of $45,000 and a beneficial conversion feature for the
100,000 shares of Series C Stock of $550,000.

     Liquidity and Capital Resources

     At  September  30,  2000 the  Company  had a  working  capital  deficit  of
$2,916,189 as compared to working capital of $414,132 at December 31, 1999. Also
at  September  30,  2000,  the Company had a  stockholders  deficit of $901,320.
Through  September 30, 2000 these  amounts  reflect the effects of the Company's
continuing losses as well as borrowings  against Notes totaling $375,000 and its
$2,500,000  line of credit,  $500,000 of which was  considered to be a long-term
liability at December 31, 1999 and Notes  totaling  $375,000  held by Dr. Derace
Schaffer and Mr. John  Pappajohn  who are  Directors  of the Company.  Since its
inception,  the Company has primarily  funded its  operations,  working  capital
needs and capital  expenditures from the sale of equity securities.  The Company
completed an initial public  offering of its common stock on January 8, 1997, at
which time it generated net proceeds to the Company of $16,314,048.

     On March 31,  2000,  the Company  completed a private  placement of 100,000
shares  of newly  issued  Series C 9%  Cumulative  Convertible  Preferred  Stock
("Series  C"),  raising  $1,000,000  in  total  proceeds.  These  shares  can be
converted  into Common Stock at a rate of 8 shares of Common Stock to 1 share of
Series C Preferred Stock.  Each Series C share has voting rights equivalent to 8
shares of Common Stock  (800,000  shares).  The proceeds from this issuance have
been used to support the Company's operations.

     The fair market value of the Company's Common Stock at the time of issuance
of Series C  Preferred  Stock was  $1.9375  per  share.  The Series C Shares are
convertable  at a price equal to $1.25 per share of Common Stock  resulting in a
discount,   or  beneficial   conversion  feature,  of  $0.6875  per  share.  The
incremental  fair value of $550,000 for the 100,000 shares of Series C Preferred
issued  is  deemed to be the  equivalent  of a  preferred  stock  dividend.  The
Comapany  recorded  the deemed  dividend at the date of  issuance by  offsetting
charges and  credits to  additional  paid-in  capital of  $550,000,  without any
effect on total  stockholders'  equity. The amount increased the loss applicable
to common  stockholders  in the  calculation of basic net loss per share for the
three and nine-month periods ended September 30, 2000. Form 10-Q/A amendments to
the Company's three and six month periods ended March 31, 2000 and June 30, 2000
respectively  were  filed  simultaneously  with this Form  10-Q to  reflect  the
adjustment  to  paid-in  capital,   reclassifications  consistent  with  current
presentation and net loss per share for such periods.  No adjustment was made to
any other information included in such filings.

     In December 1999, the Company  established a credit facility for $1,500,000
guaranteed by Derace Schaffer and John Pappajohn,  directors of the Company.  In
consideration for their guarantees,  the Company granted to Dr. Schaffer and Mr.
Pappajohn  warrants to purchase an aggregate  of 375,000  shares of common stock
for $1.5625 per share.  In March 2000,  the facility was increased by $1,000,000
under  substantially  the same terms, also guaranteed by the same Board members.
Because  this line of  credit is due and  payable  on March  31,  2001,  amounts
outstanding  at September 30, 2000 and December 31, 1999 are reported as current
and  long-term  liabilities,  respectively.  Additional  warrants to purchase an
aggregate of 250,000  shares of Common Stock for $2.325 per share,  were granted
to Dr.  Derace  Schaffer  and Mr. John  Pappajohn  for their  guarantee  of this
additional line of credit.

     In August 2000,  the Company  borrowed  $125,000  and in September  2000 an
additional $62,500 from Mr. John Pappajohn.  Proceeds from these loans were used
to support the  Company's  operations.  The  interest on these loans is 9.5% per
year.

     In August 2000,  the Company  borrowed  $125,000  and in September  2000 an
additional $62,500 from Dr. Derace Schaffer. Proceeds from these loans were used
to support the  Company's  operations.  The  interest on these loans is 9.5% per
year.

     The loans from Mr. Pappajohn and Dr. Schaffer are demand Notes and intended
to be secured by the assets of The Company.

     The Company anticipates that it will need to borrow additional funds before
it can secure additional capital through the issuance of additional  securities.
The Company's  current directors have no obligation to continue to provide funds
There can be no  assurances  given that the  company  can borrow the  additional
amounts needed or that the Company can sell additional securities.

     The  Company has  expended  substantial  amounts to expand its  operational
capabilities  and  strengthen  its  infrastructure,  which at the same  time has
increased its  administrative  and technical  costs. In addition,  the Company's
cash has been  steadily  depleted as a result of operating  losses.  The Company
anticipates  that  its  losses  will  continue  or  increase  and the  Company's
available  capital has been limited to loans from certain of its directors which
loans may not  continue  to be  available.  Accordingly,  the  Company  has been
required,  and will for the foreseeable future continue to be required,  to seek
additional  capital to maintain its  operations.  The Company is continuing  its
efforts to raise additional  capital  privately  through the sale of convertible
preferred  stock or  otherwise.  However,  no  assurance  can be given  that the
Company will be able to obtain  additional  financing on favorable  terms, if at
all. In  addition,  any  additional  financing,  which  includes the issuance of
additional  securities of the Company, may be dilutive to the Company's existing
stockholders.  If the Company is unable to identify  additional capital, it will
be required to cease operations.

     Nasdaq Listing Status

     The  Company's  securities  were  delisted  from the  Nasdaq  Stock  Market
effective September 14, 2000. The Company's securities were immediately eligible
to trade on the OTC Bulletin Board.

     Inflation

     Inflation did not have a significant  impact on the Company's  costs during
the three and  nine-month  periods  ended  September  30, 2000 and September 30,
1999.  The  Company  continues  to monitor the impact of  inflation  in order to
minimize its effects through pricing strategies,  productivity  improvements and
cost reductions.



<PAGE>



     Forward Looking Statements

     When used in this and in future  filings by the Company with the Securities
and Exchange Commission,  in the Company's press releases and in oral statements
made with the approval of an authorized  executive  officer of the Company,  the
words or phrases "will likely result,"  "expects," "plans," "will continue," "is
anticipated,"  "estimated,"  "project,"  or  "outlook"  or  similar  expressions
(including  confirmations by an authorized  executive  officer of the Company of
any such  expressions  made by a third party with  respect to the  Company)  are
intended  to  identify  "forward-looking  statements"  within the meaning of the
Private Securities  Litigation Reform Act of 1995. The Company wishes to caution
readers not to place undue reliance on any such forward-looking statements, each
of which speak only as of the date made.  Such statements are subject to certain
risks and  uncertainties  that could cause actual  results to differ  materially
from  historical  earnings and those presently  anticipated or projected.  These
uncertainties  include  risks of  market  acceptance  of or  preference  for the
Company's systems and services,  competitive  forces, the impact of, and changes
in, government regulations,  general economic factors in the healthcare industry
and other factors  discussed in the Company's  filings with the  Securities  and
Exchange  Commission.  The Company  has no  obligation  to publicly  release the
result of any revisions,  which may be made to any forward-looking statements to
reflect anticipated or unanticipated events or circumstances occurring after the
date of such statements.

     Accounting Pronouncements

     In June 1998, the Financial  Accounting  Standards  Board  ("FASB")  issued
Statement of Financial  Accounting  Standards ("SFAS") No. 133,  "Accounting for
Derivative  Instruments and Hedging  Activities".  In June 2000, the FASB issued
SFAS No. 138, which amends certain  provisions of SFAS 133 to clarify four areas
causing  difficulties in  implementation.  The amendment  included expanding the
normal  purchase  and  sale  exemption  for  supply  contracts,  permitting  the
offsetting  of  certain  intercompany  foreign  currency  derivatives  and  thus
reducing the number of third party derivatives,  permitting hedge accounting for
foreign-currency  denominated  assets and liabilities,  and redefining  interest
rate risk to reduce  sources of  ineffectiveness.  We have  appointed  a team to
implement  SFAS  133 on a  global  basis  for the  Company.  This  team has been
implementing an SFAS 133 compliant risk management information system,  globally
educating  both financial and  non-financial  personnel,  inventorying  embedded
derivatives and addressing  various other SFAS 133 related issues. We will adopt
SFAS 133 and the  corresponding  amendments  under  SFAS 138 on January 1, 2001.
SFAS 133, as amended by SFAS 138, is not  expected to have a material  impact on
the Company's condensed consolidated  financial position,  results of operations
or cash flows.

     In September 2000, the Financial Accounting Standards Board issued SFAS No.
140,   "Accounting   for  Transfers  and  Servicing  of  Financial   Assets  and
Extinguishment of Liabilities,"  which supercedes SFAS No. 125,  "Accounting for
Transfers and Servicing of Financial Assets and Extinguishments of Liabilities."
This standard is effective for transfers  occurring  after March 31, 2001,  with
certain disclosure requirements effective for the year ending December 31, 2000.
The  Company  does  not  believe  the  adoption  of this  standard  will  have a
significant impact on the Company's condensed  consolidated  financial position,
results of operations or cash flows.

     In December 1999, the Securities and Exchange Commission (SEC) issued Staff
Accounting  Bulletin  No.  101 (SAB  101),  "Revenue  Recognition  in  Financial
Statements,"  which  provides  guidance  on the  recognition,  presentation  and
disclosure  of revenue in financial  statements  filed with the SEC. SAB 101, as
amended,  is  required  to be  adopted  by the  Company no later than the fourth
quarter of fiscal year 2000.  Although  the Company has not fully  assessed  the
implications  of SAB 101,  management  does not believe the  adoption of SAB 101
will have a significant impact on the Company's condensed consolidated financial
position, results of operations or cash flows.
<PAGE>


Item 3.  Quantitative and Qualitative Disclosures About Market Risk

     The Company is exposed to changes in interest  rates  primarily in its cash
transactions.  The interest paid on the Company's  outstanding line of credit is
based upon the prime rate.  The Company has the option of reducing  its interest
expenses by rolling the outstanding line of credit balance into notes that carry
a rate equal to LIBOR plus 1.75%.

     In relation to the operations of Patient Infosystems  Canada,  fluctuations
of foreign  currency can impact the Company's net  operating  results.  However,
management  believes that due to the relative size of its  operations in Canada,
such  impact  would  be  considered  immaterial  to the  consolidated  financial
statements.  The Company  currently has no  significant  investments  in foreign
currency instruments.

     The  balances  the Company has in cash or cash  equivalents  are  generally
available without legal restrictions to fund ordinary business  operations.  The
Company  regularly  invests excess  operating  cash, if any, in  certificates of
deposit and U.S. government bonds and other bonds that are subject to changes in
short-term  interest rates.  Accordingly,  the Company  believes that the market
risk arising from its holding of these  financial  instruments  is minimal.  The
Company did not make any purchases of available-for-sale securities in the three
months ended September 30, 2000.


<PAGE>


PART II - OTHER INFORMATION

Item 2.  Changes in Securities and Use of Proceeds

     Series C Preferred Stock

     On March 31,  2000,  the Company  received  $1,000,000  in proceeds  from a
private sale of 100,000  shares of Series C  Convertible  Preferred  Stock.  The
Series C Convertible  Preferred carries a 9% cumulative  dividend  provision and
can be converted into Common Stock at a rate of 8 shares of Common to 1 share of
Preferred.  Each share of Series C Convertible Preferred Stock has voting rights
equal to the number of shares of Common Stock into which it can be converted.


Item 5.  Other Information

     Series D Preferred Stock

     On September 9, 2000, the Company  issued a term sheet to specific  private
investors  for the sale of  700,000  shares  of Series D  Convertible  Preferred
Stock.  Proceeds  of the  proposed  sale  would  be  $7,000,000.  The  Series  D
Convertible  Preferred  Stock would accrue a 9%  cumulative  dividend and can be
converted  into  Common  Stock at a rate of 10  shares  of  Common to 1 share of
Preferred Stock.  Each share of Series D Convertible  Preferred Stock would have
voting rights equal to the number of shares of Common Stock into which it can be
converted. No assurance can be given that any funds will be invested or that the
terms of the Series D  Convertible  Preferred  Stock will not change  before the
shares are sold.

     Intended Asset Aquisition

     On August  31,  2000,  the  Company  executed a Letter of Intent to acquire
substantially all the assets of American CareSource  Corporation and Health Data
Solutions  (collectively  known as "ACS/HDS").  The Company is  negotiating  the
terms of a  definitive  agreement  to  complete  this  acquisition  through  the
issuance of 7,500,000 shares of the Company's  Common Stock,  which is currently
unregistered.

     Health Data Solutions provides modular software solutions that automate all
aspects of claims processing,  including formatting,  re-pricing,  adjudication,
data transfer/EDI, payments, and data warehousing. The software can be hosted on
the client's  hardware,  accessed via the Internet as an ASP, or operated by HDS
in a fully outsourced environment.

     American CareSource provides  coordination and case management of ancillary
services  through a national  network of  contracted  providers  in 30 different
ancillary service categories.



<PAGE>




Item 6.  Exhibits and Reports on Form 8-K


Exhibits:
--------

(a) (10.40)   Form of Promissory Notes payable to Dr. Schaffer and Mr. Pappajohn

    (11)      Statements of Computation of Per Share Earnings

    (27)      Financial Data Schedule


(b) No reports on Form 8-K were filed during the quarter ended September 30,2000


<PAGE>


SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.

Dated:  November  20, 2000



                                                       PATIENT INFOSYSTEMS, INC.
                                                             (Registrant)


Date: November  20, 2000            /s/ Roger L. Chaufournier
      ------------------            --------------------------------------------
                                    Roger L. Chaufournier
                                    Director, President and
                                    Chief Executive Officer

Date: November  20, 2000            /s/ Kent A. Tapper
      ------------------            --------------------------------------------
                                    Kent A. Tapper
                                    Principal Accounting Officer




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