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<PAGE> 1
Filed Pursuant to Rule 424(b)(3)
Registration Statement No. 333-34075
Supplement
to
Prospectus dated September 22, 1997
The table of Selling Shareholders on pages 12, 13 and 14 is hereby
replaced in its entirely with the following table:
<TABLE>
<CAPTION>
Shares Shares of
Common Common
Stock Stock
Beneficially Shares Beneficially
Owned Prior Offered Owned After
to the Offering Hereby the Offering
--------------- ------ ------------
<S> <C> <C> <C>
Name of Selling Shareholders
- ----------------------------
Bruce Addis 152 152 --
Lourdes P. Aguda 29 29 --
Ellen Beaumont 125 125 --
Walter Blair 43,395 43,395 --
John E. Bramfitt and Pamela I. Bramfitt, 13,009 13,009 --
Co-Trustees FBO Bramfitt Family Trust
U/A/D/ 01/20/93
John H. Bunch 280 280 --
Jeffrey P. Callister 23,486 23,486 --
Cedar-Sinai Medical Center 3,557 3,557 --
Laura Dietch 1,874 1,874 --
Catherine Diez-Luckie 6,749 6,749 --
Neal Eigler 252,136 252,136 --
Hartmut & Maria Eysell, JT TEN 1,124 1,124 --
Glenn K. Furata 8,302 8,202 100
Mark D. Milani, Trusteee of the 22,500 22,500 --
Gabriela M. Hess Trust U/T/A/
dated November 30, 1994
Robert Hess and Rosemarie Hess, 583,524 583,524 --
Trustees FBO Hess Family Trust
U/A/D/ dated 8/3/89
Mark D. Milani, Trustee of the 22,500 22,500 --
Verona K. Hess 1994 Trust U/T/A/
dated November 30, 1994
William B. Hess 1,124 1,124 --
Jerome Jackson 8,191 8,191 --
Litvack-Curtis Children's Trust, 33,751 33,751 --
Robert Harabedian, Trustee
Frank Litvack 593,468 593,468 --
Judy Litvack Ravinsky 373 373 --
Yoh Chie Lu 8,749 8,749 --
</TABLE>
<PAGE> 2
<TABLE>
<S> <C> <C> <C>
Paul McCormick 1,640 1,640 --
Nathan Ramaswami 111 111 --
Lisa Rauh 27 27 --
Nancy Shanley 936 936 --
Fred Zuber 243 243 --
Fukuda Denshi Co., Ltd. 125,647 125,647 --
Arnhold & S. Bleichroeder, Inc. 803 803 --
(for Michelle Drasher)
Arnhold & S. Bleichroeder, Inc. 36,162 36,162 --
(for First Eagle Fund, NV)
Arnhold & S. Bleichroeder, Inc. 4,017 4,017 --
(for Gary Fuhrman)
Arnhold & S. Bleichroeder, Inc. 4,017 4,017 --
(for Harold Levy)
Stephen Aiello 601 601 --
AS Fansea 401 401 --
Howard Berlin 3,013 3,013 --
John Bohan 401 401 --
David L. Cohen 3,214 3,214 --
Bryan C. Donohue, M.D. 1,004 1,004 --
Michael Dovey 1,004 1,004 --
Paine Webber in Trust of the Jonathan Edelson IRA 803 803 --
Evelin Eigler, Trustee of the Seldon Baker Trust 1,003 1,003 --
Stuart M. Essig 1,004 1,004 --
John S. Geis 4,017 4,017 --
Claudio Gibelli 2,008 2,008 --
GSAM Oracle Fund, Inc. 24,108 24,108 --
Hare & Co. 26,116 26,116 --
William M. Helvey, M.D. 1,004 1,004 --
John B. Henneman, III 401 401 --
Steven Hochberg 803 803 --
Hoegh Invest AS 2,611 2,611 --
Alice Jack 1,004 1,004 --
Earl L. and Julia Ender Jackson 1,004 1,004 --
as Community Property
FBO Ronald P. Karlsberg Cardiovascular Group 901 601 300
of Southern California 401(k)
Profit Sharing Plan DTD 1/1/89
Gerald T. Keusch 601 601 --
Kurt H. Kruger 803 803 --
Jack Litvack, Cyst Investment Corp. 3,004 1,004 2,000
Patrick A. McBrayer 401 401 --
J. Casey McGlynn 160 160 --
David Moyne 803 803 --
David B. Musket 5,745 5,745 --
Cowen & Co., 903 903 --
Custodian FBO David B. Musket SEP IRA
August J. Neudecker 4,017 4,017 --
Och-Ziff Capital Management, L.P. 30,134 30,134 --
</TABLE>
<PAGE> 3
<TABLE>
<S> <C> <C> <C>
Daniel P. Paduano 3,013 3,013 --
Munro W. Pitt 602 602 --
ProMed Partners, L.P. 13,560 13,560 --
Prudential Securities 2,009 2,009 --
C/F Colin Morris A/C AA-R54811
Randall Rose 16,072 16,072 --
Clinton T. Rubin (SUNY - Stony Brook) 401 401 --
J. Curt Schnackenberg 1,004 1,004 --
Lorraine A. Schwarz 1,004 1,004 --
Dieter Stoeckel 560 360 200
Lawrence J, Tedesco, Sr. 441 441 --
The Travelers Indemnity Company 44,197 44,197 --
The Travelers Insurance Company 85,383 85,383 --
The Travelers Life and Annuity Company 5,021 5,021 --
The Phoenix Insurance Company 6,026 6,026 --
Westfield Performance Fund, L.P. 20,089 20,089 --
WS Investment Company 96A 1,445 1,445 --
James Whiting 538 538 --
Wilson, Sonsini, Goodrich & Rosati Profit Sharing 401 401 --
Plan, Mario M. Rosati and Douglas
M. Laurice, Trustees, FBO J. Casey McGlynn
Wood Grundy (London) Ltd. 125 125 --
Ashtree Corporation 1,799 1,799 --
Jim Lane 1,799 1,799 --
Paine Webber Inc., as custodian of the IRA 1,079 1,079 --
account of Jason F. Fensterstock
Paine Webber Inc., as custodian of the IRA 1,799 1,799 --
account of Joyce Fensterstock
Paine Webber Inc., as custodian of the IRA 899 899 --
IRA account of Blair Fensterstock
Richard Yancy 899 899 --
Stephen Case 899 899 --
Brad Stephens 539 539 --
Edward Kosinski 1,799 1,799 --
Janet Tweed-Arkush 539 539 --
Gary Schonwald 899 899 --
JIBJEB Partners 899 899 --
John Friedman 2,116 2,116 --
Steven Casey 473 473 --
Khalid Quadir 76 76 --
Edward Casey 539 539 --
Auldgate Investments 4,192 4,192 --
--------- --------- -----
Total: 2,148,132 2,145,532 2,600
========= ========== =====
</TABLE>
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