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<PAGE> 1
Filed Pursuant to Rule 424(b)(3)
Registration Statement No. 333-34075
Supplement
to
Prospectus dated September 22, 1997
The table of Selling Shareholders on pages 12, 13 and 14 is hereby
replaced in its entirely with the following table:
<TABLE>
<CAPTION>
Shares Shares of
Common Common
Stock Stock
Beneficially Shares Beneficially
Owned Prior Offered Owned After
to the Offering Hereby the Offering
--------------- -------------- ---------------
<S> <C> <C> <C>
NAME OF SHAREHOLDERS
Bruce Addis 151 151
Lourdes P. Aguda 29 29
Ellen Beaumont 124 124
Walter Blair 69,896 69,896
John E. Bramfitt and Pamela I. Bramfitt, 13,004 13,004
Co-Trustees FBO Bramfitt Family Trust
U/A/D/ 01/20/93
John H. Bunch 279 279
Jeffrey P. Callister 23,479 23,479
Laura Dietch 5,621 5,621
Catherine Diez-Luckie 24,824 24,824
Neal Eigler 252,068 252,068
Hartmut & Maria Eysell, JT TEN 1,122 1,122
Glenn K. Furuta 19,779 19,679 100
Mark D. Milani, Trusteee of the 22,493 22,493
Gabriela M. Hess Trust U/T/A/
dated November 30, 1994
Robert Hess and Rosemarie Hess, 583,370 583,370
Trustees FBO Hess Family Trust
U/A/D/ dated 8/3/89
Mark D. Milani, Trustee of the 22,493 22,493
Verona K. Hess 1994 Trust U/T/A/
dated November 30, 1994
William B. Hess 1,122 1,122
Jerome Jackson 8,188 8,188
Litvack-Curtis Children's Trust, 33,741 33,741
Robert Harabedian, Trustee
Frank Litvack 596,868 596,868
Judy Litvack Ravinsky 372 372
Yoh Chie Lu 8,745 8,745
Paul McCormick 8,433 8,433
Nathan Ramaswami 111 111
Lisa Rauh 28 28
Nancy Shanley 936 936
Fred Zuber 242 242
Fukuda Denshi Co., Ltd. 125,613 125,613
Arnhold & S. Bleichroeder, Inc. 802 802
(for Michelle Drasher)
Arnhold & S. Bleichroeder, Inc. 36,151 36,151
(for First Eagle Fund, NV)
Arnhold & S. Bleichroeder, Inc. 4,015 4,015
(for Gary Fuhrman)
Arnhold & S. Bleichroeder, Inc. 4,015 4,015
(for Harold Levy)
</TABLE>
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<PAGE> 2
<TABLE>
<S> <C> <C> <C>
Stephen Aiello 600 600
AS Fansea 400 400
Howard Berlin 3,012 3,012
John Bohan 400 400
David L. Cohen 3,211 3,211
Bryan C. Donohue, M.D. 3,009 3,009
Michael Dovey 1,003 1,003
Paine Webber in Trust of the Jonathan Edelson IRA 802 802
Evelin Eigler, Trustee of the Seldon Baker Trust 1,002 1,002
Stuart M. Essig 1,003 1,003
John S. Geis 4,015 4,015
Claudio Gibelli 2,006 2,006
GSAM Oracle Fund, Inc. 24,101 24,101
Hare & Co. 26,108 26,108
William M. Helvey, M.D. 1,003 1,003
John B. Henneman, III 400 400
Steven Hochberg 802 802
Hoegh Invest AS 2,609 2,609
Alice Jack 1,003 1,003
Earl L. and Julia Ender Jackson 1,003 1,003
as Community Property
FBO Ronald P. Karlsberg Cardiovascular Group 900 600 300
of Southern California 401(k)
Profit Sharing Plan DTD 1/1/89
Gerald T. Keusch 600 600
Kurt H. Kruger 802 802
Jack Litvack, Cyst Investment Corp. 3,003 1,003 2,000
Patrick A. McBrayer 400 400
J. Casey McGlynn 159 159
David Moyne 802 802
David B. Musket 5,742 5,742
Cowen & Co., 903 903
Custodian FBO David B. Musket SEP IRA
August J. Neudecker 4,015 4,015
Och-Ziff Capital Management, L.P. 30,126 30,126
Daniel P. Paduano 3,012 3,012
Munro W. Pitt 601 601
ProMed Partners, L.P. 13,555 13,555
Prudential Securities 2,007 2,007
C/F Colin Morris A/C AA-R54811
Randall Rose 16,066 16,066
Clinton T. Rubin (SUNY - Stony Brook) 400 400
J. Curt Schnackenberg 1,003 1,003
Lorraine A. Schwarz 1,003 1,003
Dieter Stoeckel 559 359 200
Lawrence J, Tedesco, Sr. 440 440
The Travelers Indemnity Company 44,185 44,185
The Travelers Insurance Company 85,359 85,359
The Travelers Life and Annuity Company 5,018 5,018
The Phoenix Insurance Company 6,024 6,024
Westfield Performance Fund, L.P. 20,082 20,082
WS Investment Company 96A 1,443 1,443
James Whiting 537 537
Wilson, Sonsini, Goodrich & Rosati Profit Sharing 400 400
Plan, Mario M. Rosati and Douglas
M. Laurice, Trustees, FBO J. Casey McGlynn
Federico Gutierrez 84 84
David B. Modesitt 479 479
Sheldon King 3,372 3,372
Martin Leon M.D. 5,622 5,622
Paul Teirstein M.D. 2,812 2,812
</TABLE>
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<PAGE> 3
<TABLE>
<S> <C> <C> <C>
Wood Grundy (London) Ltd. 132 132
Ashtree Corporation 1,805 1,805
Jim Lane 1,805 1,805
Paine Webber Inc., as custodian of the IRA 1,082 1,082
account of Jason F. Fensterstock
Paine Webber Inc., as custodian of the IRA 1,805 1,805
account of Joyce Fensterstock
Paine Webber Inc., as custodian of the IRA 902 902
IRA account of Blair Fensterstock
Richard Yancy 902 902
Stephen Case 902 902
Brad Stephens 540 540
Edward Kosinski 1,805 1,805
Janet Tweed-Arkush 540 540
Gary Schonwald 902 902
JIBJEB Partners 902 902
John Friedman 2,104 2,104
Steven Casey 470 470
Khalid Quadir 74 74
Edward Casey 540 540
Auldgate Investments 4,192 4,192
Adzich, Vaso 299 299
Ayrapetian, Angela 130 130
Bachrach, Alan 1,123 1,123
Baldwin, Scott 1,798 1,798
Bauer, Laura L. 224 224
Calvarese, Barry 14,057 14,057
Chernomorsky, Ary S. 1,034 1,034
Cooper, Irvin 1,685 1,685
Elam, Eric W. 188 188
Goldenberg, Tsvi 2,248 2,248
Hammack, Amy L. 103 103
Herd, Allison 261 261
Holmes, M.D., David 3,372 3,372
Khaira, Gurpreet 56 56
Krasney, Karen 575 575
Kuhn, Larry 1,685 1,685
Lin, Stuart H. 188 188
Maharaj, Kishore 74 74
McCormic, Frank P. 289 289
McKenzie, Jim 1,701 1,701
Mendoza, Graciela Ortega 111 111
Meyer, Barry D. 579 579
Park, Kinam 1,859 1,859
Pena, Uriel 88 88
Pinon, Hortensia 289 289
Ramzipoor, Kamal 1,909 1,909
Reitman, Martha 1,348 1,348
Sudaria, Rodolfo 149 149
Surgener, David L. 224 224
Trinidad, Jocelyn 74 74
Viravouth, Chandavone 74 74
Wilson, Sally J. 1,920 1,920
--------------- -------------- ---------------
Total: 2,268,239 2,265,639 2,600
=============== ============== ===============
</TABLE>
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