WORLDWIDE HEALTH SCIENCES PORTFOLIO
POS AMI, 1996-12-30
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    As filed with the Securities and Exchange Commission on December __, 1996
    
                                                            File No. 811-07723

                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549



                                    FORM N-1A


                             REGISTRATION STATEMENT
                                      UNDER
                     THE INVESTMENT COMPANY ACT OF 1940 [X]

   
                                 AMENDMENT NO. 1
    

                       WORLDWIDE HEALTH SCIENCES PORTFOLIO
               (Exact Name of Registrant as Specified in Charter)

                        The Bank of Nova Scotia Building
                     P.O. Box 501, George Town, Grand Cayman
                       Cayman Islands, British West Indies
                    (Address of Principal Executive Offices)


       Registrant's Telephone Number, Including Area Code: (809) 949-2001


                                   Thomas Otis
                 24 Federal Street, Boston, Massachusetts 02110
                     (Name and Address of Agent for Service)




<PAGE>





                                EXPLANATORY NOTE


         This Registration  Statement has been filed by the Registrant  pursuant
to Section  8(b) of the  Investment  Company Act of 1940,  as amended.  However,
interests in the Registrant are not being registered under the Securities Act of
1933, as amended (the "1933 Act"),  because such interests will be issued solely
in private  placement  transactions  that do not involve  any "public  offering"
within  the  meaning  of  Section  4(2)  of the  1933  Act.  Investments  in the
Registrant may be made only by U.S. and foreign investment companies,  common or
commingled trust funds,  organizations or trusts described in Sections 401(a) or
501(a)  of  the  Internal   Revenue  Code  of  1986,  as  amended,   or  similar
organizations or entities that are "accredited  investors" within the meaning of
Regulation D under the 1933 Act. This Registration Statement does not constitute
an offer to sell, or the  solicitation  of an offer to buy, any interests in the
Registrant.


                                    


<PAGE>


                                     PART A

         Responses  to Items 1 through 3 and 5A have been  omitted  pursuant  to
Paragraph 4 of Instruction F of the General Instructions to Form N-1A.

Item 4.  General Description of Registrant

         Worldwide Health Sciences Portfolio (the "Portfolio") is a diversified,
open-end management  investment company which was organized as a trust under the
laws of the State of New York on March 26, 1996.  Interests in the Portfolio are
issued solely in private placement  transactions that do not involve any "public
offering"  within the meaning of Section 4(2) of the  Securities Act of 1933, as
amended (the "1933 Act").  Investments in the Portfolio may be made only by U.S.
and  foreign   investment   companies,   common  or   commingled   trust  funds,
organizations  or trusts  described in Section  401(a) or 501(a) of the Internal
Revenue  Code of 1986,  as amended (the  "Code"),  or similar  organizations  or
entities  that are  "accredited  investors"  within the meaning of  Regulation D
under the 1933 Act. This Registration  Statement does not constitute an offer to
sell, or the solicitation of an offer to buy, any "security"  within the meaning
of the 1933 Act.

         The Portfolio's  investment  objective is long-term capital growth. The
Portfolio  seeks  to  achieve  its  objective  by  investing  in  a  global  and
diversified portfolio of securities of health sciences companies.

         The  Portfolio  is  intended  for  long-term  investors  who can accept
international  investment  risk and little or no  current  income.  Because  the
Portfolio  concentrates  its investments in medical research and the health care
industry,  the  Portfolio is not intended to be a complete  investment  program.
Prospective  investors  should  take into  account  their  objectives  and other
investments when  considering the purchase of an interest in the Portfolio.  The
Portfolio cannot assure achievement of its investment objective. See "Investment
Policies and Risks" for further  information.  The  investment  objective of the
Portfolio  is  nonfundamental.   Additional  information  about  the  investment
policies of the Portfolio appears in Part B.

Health Science Investments


   
         Markets  for health  sciences  products  and  services  have  undergone
significant growth over the last 25 years. In the U.S., the Department of Health
and Human Services  estimates  healthcare  expenditures  alone could increase to
over 16% of gross national product by the year 2000, compared to 7.6%, 10.3% and
14.0% in 1972,  1982 and 1992,  respectively.  Outside the U.S.,  most developed
countries are seeing  similar  growth in health care  expenditures.  In emerging
markets, health care spending is increasing as standards of living are improving
and as revenues  become  available to fund  government  and private  programs to
address  basic  health  needs.  Factors  contributing  to  this  growth  include
demographic  shifts  tending to a higher world  population  and a larger elderly
population  in  industrialized  nations,  technological  advances,  and  popular
acceptance of and worldwide  familiarity with healthcare products,  resulting in
high  consumer  demand.  In  addition  to  increased  demand for health  science
products and  services,  substantial  public and private  expenditures  on basic
medical research and advances in technology have accelerated the pace of medical
discoveries.   The  Portfolio's   investment  adviser,  Mehta  and  Isaly  Asset
Management, Inc. ("M&I" or the "Adviser"),  believes that the rate of change may
accelerate in the future,  causing  certain  segments of the business to decline
and others to experience growth. Favorable investment opportunities may be found
in companies  that  provide  products or services  designed for the  prevention,
diagnosis and treatment of physical and mental disorders.
    

         In making  portfolio  selections,  in addition to evaluating  trends in
corporate revenues,  earnings and dividends, the Adviser generally considers the
amount of capital currently being expended on research and development,  and the
nature  thereof.  The Adviser  believes  that  dollars  invested in research and
development today frequently have significant bearing on future growth.

         Portfolio  securities  generally will be selected from companies in the
following groups:

         Biotechnology  - Companies  which are producing or plan to produce as a
result of current research,  diagnostic and therapeutic drugs and reagents based
on genetic  engineering  and the use of monoclonal  antibodies or on recombinant
DNA;  also,   specialty   companies  catering  to  the  unique  requirements  of
biotechnology  companies such as those providing enzymes, media and purification
equipment.

         Diagnostics   -  Private   organizations   that   develop  or  maintain
sophisticated  diagnostic  equipment such as CAT scanners and Magnetic Resonance
Imaging as well as urological and serological assays.

         Managed  Healthcare  -  Operators  of  investor-owned  hospital  chains
(including acute care psychiatric  hospitals),  nursing centers for the elderly,
health  maintenance  organizations,  and  rehabilitation  clinics  which seek to
deliver hospital care on an efficient cost basis.

         Medical  Equipment and Supplies - Companies  engaged in the manufacture
of inpatient and  outpatient  medical (and  dental),  surgical,  laboratory  and
diagnostic products (ranging from cotton swabs through kidney dialyses equipment
to CAT scanners).

         Pharmaceuticals - Companies  involved with new types of drugs and their
delivery systems.

         By focusing on companies  such as the foregoing,  the Adviser  believes
that the opportunity for long-term capital growth exists.  Of course,  there can
be no  assurance  that  the  Portfolio  will be able  to take  advantage  of the
foregoing   opportunities,   or  that  such  investment  opportunities  will  be
favorable.

Investment Policies and Risks

         The  Portfolio  invests  in  a  global  and  diversified  portfolio  of
securities of health sciences companies. These companies principally are engaged
in the  development,  production or distribution of products or services related
to scientific  advances in  healthcare,  including  biotechnology,  diagnostics,
managed healthcare, medical equipment and supplies, and pharmaceuticals.  At the
time the Portfolio makes an investment,  50% or more of such a company's  sales,
earnings or assets will arise from or will be  dedicated to the  application  of
scientific  advances  related  to  healthcare.   The  Portfolio  may  invest  in
securities  of both  established  and emerging  companies,  some of which may be
denominated in foreign currencies.

   
         Under normal market conditions,  the Portfolio will invest at least 65%
of its assets in securities of health science  companies,  including  common and
preferred  stocks;  equity  interests  in  partnerships;  convertible  preferred
stocks;  and  other  convertible   instruments.   Convertible  debt  instruments
generally will be rated below  investment  grade (i.e.,  rated lower than Baa by
Moody's Investors  Service,  Inc. or lower than BBB by Standard & Poor's) or, if
unrated, determined by the Adviser to be of equivalent quality. Convertible debt
securities  so rated are commonly  called "junk bonds" and have risks similar to
equity  securities;  they are speculative and changes in economic  conditions or
other  circumstances  are more  likely to lead to a  weakened  capacity  to make
principal  and  interest  payments  than is the  case  with  higher  grade  debt
securities.  Such below  investment grade debt securities will not exceed 20% of
total assets. For temporary defensive purposes, the Portfolio may invest without
limit in debt  securities  of  foreign  and  United  States  companies,  foreign
governments   and  the  U.S.   Government,   and  their   respective   agencies,
instrumentalities,  political  subdivisions and authorities,  as well as in high
quality money market  instruments.  In addition,  the Portfolio may  temporarily
borrow up to 5% of the value of its total assets to satisfy redemption  requests
or settle securities transactions.
    
   
         An  investment  in the  Portfolio  entails the risk that the  principal
value of  interests  in the  Portfolio  may not  increase  or may  decline.  The
Portfolio's  investments  are  subject  to  the  risk  of  adverse  developments
affecting  particular  companies,  the health science  industries and securities
markets  generally.  The value of interests in the Portfolio may fluctuate  more
than investments in a broader range of industries. Many health science companies
are  subject to  substantial  governmental  regulations  that can  affect  their
prospects.  Changes in governmental policies,  such as reductions in the funding
of third-party  payment  programs,  may have a material effect on the demand for
particular  health care  products  and  services.  Regulatory  approvals  (often
entailing  lengthy  application  and  testing  procedures)  are  also  generally
required  before new drugs and certain  medical  devices and  procedures  may be
introduced.  Many of the products  and services of companies  engaged in medical
research  and health  care are also  subject to  relatively  high risks of rapid
obsolescence caused by progressive  scientific and technological  advances.  The
enforcement  of patent,  trademark  and other  intellectual  property  laws will
affect  the  value of many of such  companies.  The  Portfolio  will  invest  in
securities of emerging growth health science companies,  which may offer limited
products or services or which are at the research and development  stage with no
marketable or approved products or technologies.  The Portfolio may invest up to
15% of its net assets in illiquid securities, which excludes securities eligible
for resale under Rule 144A of the 1933 Act that the Portfolio's Trustees and the
Adviser  determine  are  liquid.  Holding  Rule  144A  securities  may  increase
illiquidity  if qualified  institutional  buyers become  uninterested  in buying
them.
    
   
     Investing in Foreign Securities.  Investing in securities issued by foreign
companies  and  governments  involves  considerations  and  possible  risks  not
typically  associated with investing in securities issued by the U.S. Government
and domestic  corporations.  The values of foreign  investments  are affected by
changes in  currency  rates or  exchange  control  regulations,  application  of
foreign  tax  laws  (including   withholding   tax),   changes  in  governmental
administration  or economic or monetary  policy (in this country or abroad),  or
changed  circumstances in dealings between  nations.  Foreign currency  exchange
rates may  fluctuate  significantly  over  short  periods  of time  causing  the
Portfolio's  net  asset  value to  fluctuate  as well.  Costs  are  incurred  in
connection with conversions  between various  currencies.  In addition,  foreign
brokerage  commissions,  custody fees and other costs of investing are generally
higher than in the United  States,  and foreign  securities  markets may be less
liquid,  more volatile and less subject to governmental  supervision than in the
United  States.  Investments in foreign  issuers could be adversely  affected by
other  factors  not  present  in the  United  States,  including  expropriation,
confiscatory  taxation,  lack of uniform accounting and auditing standards,  and
potential  difficulties  in enforcing  contractual  obligations.  In addition to
investing in foreign  companies of countries  which  represent  established  and
developed  economies,  the  Portfolio  may also invest some of its assets in the
emerging  economies of lesser  developed  countries such as China and India, and
countries  located in Latin  America and  Eastern  Europe.  Consistent  with its
investment  objective,  the Portfolio is not limited in the percentage of assets
it may invest in such  securities  but the number of health  science  issuers in
lesser  developed  countries is relatively  small. The relative risk and cost of
investing  in the  securities  of companies in such  emerging  economies  may be
higher  than  an  investment  in  securities  of  companies  in  more  developed
countries. As of the date hereof, the Adviser initially expects to invest 50% of
the Portfolio's assets in foreign securities.
    
   
     Derivative  Instruments.  The  Portfolio  may  purchase or sell  derivative
instruments  (which  are  instruments  that  derive  their  value  from  another
instrument,  security,  index or currency) to enhance  return,  to hedge against
fluctuations in securities prices, interest rates or currency exchange rates, or
as a  substitute  for the  purchase or sale of  securities  or  currencies.  The
Portfolio's  transactions in derivative instruments may be in the U.S. or abroad
and may  include  the  purchase  or sale of  futures  contracts  on  securities,
securities indices,  other indices,  other financial  instruments or currencies;
options on futures contracts;  exchange-traded and  over-the-counter  options on
securities,  indices  or  currencies;  and  forward  foreign  currency  exchange
contracts. The Portfolio's transactions in derivative instruments involve a risk
of loss or  depreciation  due to:  unanticipated  adverse  changes in securities
prices,  interest rates, the other financial  instruments'  prices,  or currency
exchange  rates;  the  inability  to  close  out  a  position;  default  by  the
counterparty;  imperfect  correlation  between a position and the desired hedge;
tax constraints on closing out positions;  and portfolio management  constraints
on securities subject to such transactions.  The loss on derivative  instruments
(other than purchased options) may substantially  exceed the Portfolio's initial
investment in these instruments.  In addition, the Portfolio may lose the entire
premium paid for  purchased  options that expire  before they can be  profitably
exercised by the Portfolio.  The Portfolio incurs  transaction  costs in opening
and closing positions in derivative instruments.  There can be no assurance that
the  Adviser's  use  of  derivative  instruments  will  be  advantageous  to the
Portfolio.
    
   
         To the extent that the Portfolio enters into futures contracts, options
on futures  contracts  and options on foreign  currencies  traded on an exchange
regulated by the Commodity  Futures Trading  Commission  ("CFTC"),  in each case
that are not for bona fide  hedging  purposes  (as  defined  by the  CFTC),  the
aggregate  initial  margin and premiums  required to establish  these  positions
(excluding the amount by which options are  "in-the-money") may not exceed 5% of
the liquidation value of the Portfolio's investments,  after taking into account
unrealized  profits and  unrealized  losses on any  contracts  the Portfolio has
entered into.
    
         Forward  contracts are individually  negotiated and privately traded by
currency traders and their customers.  A forward contract involves an obligation
to purchase or sell a specific  currency (or basket of currencies) for an agreed
price at a future  date,  which may be any fixed number of days from the date of
the  contract.  The  Portfolio  may  engage in  cross-hedging  by using  forward
contracts  in  one  currency  (or  basket  of   currencies)   to  hedge  against
fluctuations in the value of securities  denominated in a different  currency if
the  Adviser  determines  that  there is an  established  historical  pattern or
correlation  between the two  currencies  (or the basket of  currencies  and the
underlying  currency).  Use  of  a  different  foreign  currency  magnifies  the
Portfolio's  exposure  to  foreign  currency  exchange  rate  fluctuations.  The
Portfolio  may also use  forward  contracts  to shift its  exposure  to  foreign
currency exchange rate changes from one currency to another.

Currency Swaps. The Portfolio may enter into currency swaps for both hedging and
non-hedging  purposes.  Currency swaps involve the exchange of rights to make or
receive payments in specified currencies.  Since currency swaps are individually
negotiated, the Portfolio expects to achieve an acceptable degree of correlation
between its  portfolio  investments  and its currency swap  positions.  Currency
swaps  usually  involve  the  delivery  of the  entire  principal  value  of one
designated  currency in exchange for the other designated  currency.  Therefore,
the entire  principal  value of a currency  swap is subject to the risk that the
other party to the swap will default on its  contractual  delivery  obligations.
The use of  currency  swaps  is a highly  specialized  activity  which  involves
special  investment  techniques  and risks.  If the Adviser is  incorrect in its
forecasts  of  market  values  and  currency  exchange  rates,  the  Portfolio's
performance will be adversely affected.

Repurchase  Agreements.  The Portfolio may enter into repurchase agreements with
respect to its permitted  investments,  but currently intends to do so only with
member  banks of the  Federal  Reserve  System or with  primary  dealers in U.S.
Government  securities.  In the event of the  bankruptcy of the other party to a
repurchase  agreement,  the Portfolio might experience  delays in recovering its
cash.  To the extent that,  in the  meantime,  the value of the  securities  the
Portfolio  purchased may have decreased,  the Portfolio could experience a loss.
The  Portfolio  does not  expect to invest  more than 5% of its total  assets in
repurchase agreements under normal circumstances.

Other Investment Companies. The Portfolio reserves the right to invest up to 10%
of its total assets in the securities of other investment companies unaffiliated
with the  Adviser  or Eaton  Vance  Management  ("Eaton  Vance")  that  have the
characteristics  of  closed-end   investment   companies.   The  Portfolio  will
indirectly  bear  its  proportionate  share  of  any  management  fees  paid  by
investment companies in which it invests in addition to the advisory fee paid by
the Portfolio. The value of closed-end investment securities,  which are usually
traded on an exchange, is affected by the demand for the securities  themselves,
independent of the demand for the underlying portfolio assets and,  accordingly,
such securities can trade at a discount from their net asset values.
   
Certain  Investment  Policies.  The  Portfolio has adopted  certain  fundamental
investment  restrictions  which are enumerated in detail in Part B and which may
not be changed unless  authorized by an investor vote.  Investment  restrictions
are considered at the time of acquisition of assets and, in general, the sale of
portfolio assets  generally is not required in the event of a subsequent  change
in  circumstances.  As a matter of  fundamental  policy the  Portfolio  will not
invest 25% or more of its total assets in the  securities  of issuers in any one
industry,  other  than  U.S.  Government  securities  and  securities  of health
sciences companies. However, the Portfolio is permitted to invest 25% or more of
its total assets in (i) the securities of issuers located in any one country and
(ii)  securities  denominated  in the currency of any one country.  Under normal
market  conditions,  the  Portfolio  will hold  securities of issues in at least
three countries.
    

         Except  for  the  fundamental  investment   restrictions  and  policies
specifically  identified  above and those  enumerated in Part B, the  investment
objective  and  policies  of the  Portfolio  are not  fundamental  policies  and
accordingly may be changed by the Trustees without obtaining the approval of the
investors in the  Portfolio.  The  Portfolio's  investors  will receive  written
notice  thirty  days  prior to any  change in the  investment  objective  of the
Portfolio.  If any changes were made,  the  Portfolio  might have an  investment
objective different from the objective which an investor considered  appropriate
at the time of its initial investment.

Item 5.  Management of the Portfolio

         The  Portfolio  is  organized as a trust under the laws of the State of
New York. The Portfolio intends to comply with all applicable  federal and state
securities laws.

   
Adviser.  The  Portfolio  has  engaged  Mehta and Isaly Asset  Management,  Inc.
("M&I"),  located  at  41  Madison  Avenue,  40th  Floor,  New  York,  New  York
10010-2202,  as its  investment  adviser.  M&I was  incorporated  in Delaware on
February 24, 1989 and is principally owned by Samuel D. Isaly, who serves as the
President of M&I. The Portfolio is the only investment  company registered under
the  Investment  Company  Act of 1940 (the "1940  Act")  advised  by M&I,  which
formerly was named G/A Capital Management, Inc.
    
   
        Investment  decisions  for the  Portfolio  are  made  by the  portfolio
manager,  Samuel D. Isaly. Mr. Isaly has been active in international and health
care investing  throughout his career,  beginning at Chase Manhattan Bank in New
York in 1968. He studied international  economics,  mathematics and econometrics
at  Princeton  and  the  London  School  of  Economics.  His  company,  Gramercy
Associates,  was the first to develop an integrated worldwide system of analysis
on  the  100  leading  worldwide  pharmaceutical   companies,   with  investment
recommendations  conveyed  to 50 leading  financial  institutions  in the United
States and Europe beginning in 1982.  Gramercy Associates was absorbed into S.G.
Warburg & Company Inc. in 1986,  where Mr. Isaly became a Senior Vice President.
In July of 1989, Mr. Isaly joined with Dr. Viren Mehta to found the  partnership
of Mehta and Isaly.  The  operations  of the combined  effort are (1) to provide
investment ideas to  institutional  investors on the subject of worldwide health
care,  (2) to  undertake  cross-border  merger and  acquisition  projects in the
industry  and  (3)  to  provide  investment   management  services  to  selected
investors.  The latter activity is undertaken through the legal entity Mehta and
Isaly Asset  Management,  Inc., which is an investment  advisory firm registered
with the Securities and Exchange Commission (the "Commission").
    
   
         For its services, M&I receives a fee computed daily and payable monthly
at an annual rate of 1.00% of the Portfolio's average daily net assets up to $30
million of such assets,  0.90% of the next $20 million of such assets, and 0.75%
on such assets in excess of $50 million. The fee rate declines for net assets of
$500  million  and  greater.  Beginning  September  1, 1997,  M&I may  receive a
performance  based adjustment of up to 0.25% of the net assets of the Portfolio.
M&I has agreed to pay Eaton Vance  Distributors,  Inc. ("EVD") the equivalent of
one-third of its advisory  fee  receipts  out of M&I's own  resources  for EVD's
activities as placement agent of the Portfolio.
    
   
         The Adviser furnishes for the use of the Portfolio office space and all
necessary  office   facilities,   equipment  and  personnel  for  servicing  the
investments  of the  Portfolio.  The  Adviser  places the  portfolio  securities
transactions  of the Portfolio with many  broker-dealer  firms and uses its best
efforts  to  obtain   execution  of  such   transactions  at  prices  which  are
advantageous to the Portfolio and at reasonably  competitive  commission  rates.
Subject to the  foregoing,  the Adviser may  consider  sales of shares of one or
more  investment  companies  sponsored  by the  Adviser,  Eaton  Vance  or their
affiliates or shares of any investment  company  investing in the Portfolio as a
factor  in the  selection  of  firms  to  execute  portfolio  transactions.  The
Portfolio and M&I have adopted Codes of Ethics  relating to personal  securities
transactions.  The Codes permit M&I personnel to invest in securities (including
securities  that  may be  purchased  or held by the  Portfolio)  for  their  own
accounts, subject to certain restrictions and reporting procedures.
    
   
Administrator.  Eaton Vance,  its affiliates and its predecessor  companies have
been managing  assets of individuals  and  institutions  since 1924 and managing
investment  companies  since  1931.  Eaton Vance acts as  investment  adviser to
investment  companies  and various  individual  and  institutional  clients with
assets  under  management  of over $16  billion.  Eaton Vance is a  wholly-owned
subsidiary of Eaton Vance Corp., a publicly-held  holding company that,  through
its subsidiaries  and affiliates,  engages  primarily in investment  management,
administration  and marketing  activities.  The  Portfolio's  placement agent is
Eaton Vance Distributors, Inc.("EVD"), which is a wholly-owned subsidiary of
Eaton Vance.
    
         Acting  under the general  supervision  of the Board of Trustees of the
Portfolio,  Eaton Vance administers the business affairs of the Portfolio. Eaton
Vance's services include monitoring and providing reports to the Trustees of the
Portfolio concerning the investment  performance achieved by the Adviser for the
Portfolio, recordkeeping, preparation and filing of documents required to comply
with  federal and state  securities  laws,  supervising  the  activities  of the
custodian of the Portfolio,  providing  assistance in connection  with Trustees'
and  interestholders'  meetings and other  administrative  services necessary to
conduct the business of the Portfolio. Eaton Vance also furnishes for the use of
the Portfolio  office space and all necessary office  facilities,  equipment and
personnel for administering  the business affairs of the Portfolio.  Eaton Vance
does  not  provide  any  investment  management  or  advisory  services  to  the
Portfolio.

         Under its  administration  agreement  with the  Portfolio,  Eaton Vance
receives  a  monthly  administration  fee in the  amount of 1/48 of 1% (equal to
0.25%  annually)  of the average  daily net assets of the  Portfolio  up to $500
million,  which fee  declines at  intervals  above $500  million.  The  combined
investment  advisory and administration fees payable by the Portfolio are higher
than similar fees charged by most other investment companies.
   
         The Portfolio will be  responsible  for the payment of all of its costs
and  expenses  not  expressly  stated to be  payable  by the  Adviser  under the
investment  advisory  agreement  or by  Eaton  Vance  under  the  administration
agreement. Such costs and expenses to be borne by the Portfolio include, without
limitation:  custody fees and expenses, including those incurred for determining
net asset value and keeping  accounting  books and records;  expenses of pricing
and valuation  services;  membership dues in investment  company  organizations;
brokerage  commissions  and fees;  fees and  expenses of  registering  under the
securities laws; expenses of reports to investors;  proxy statements,  and other
expenses  of  investors'  meetings;  insurance  premiums;  printing  and mailing
expenses;  interest,  taxes and corporate fees;  legal and accounting  expenses;
compensation  and  expenses of Trustees not  affiliated  with Eaton Vance or the
Adviser;  and investment  advisory and  administration  fees. The Portfolio will
also bear  expenses  incurred in  connection  with any  litigation  in which the
Portfolio  is a party and any legal  obligation  to  indemnify  its officers and
Trustees with respect thereto, to the extent not covered by insurance.
    
Transfer Agent.  IBT Fund Services  (Canada) Inc., 1 First Canadian Place,  King
Street West,  Suite 2800,  P.O.  Box 231,  Toronto,  Ontario,  Canada M5X 1C8, a
subsidiary of Investors Bank & Trust Company, the Portfolio's custodian,  serves
as transfer  agent and  dividend-paying  agent of the Portfolio and computes the
daily net asset value of interests in the Portfolio.

Item 6.  Capital Stock and Other Securities

         The  Portfolio  is  organized as a trust under the laws of the State of
New York and intends to be treated as a  partnership  for federal tax  purposes.
Under the  Declaration of Trust,  the Trustees are authorized to issue interests
in the  Portfolio.  Each  investor is entitled  to a vote in  proportion  to the
amount of its investment in the Portfolio.  Investments in the Portfolio may not
be  transferred,  but  an  investor  may  withdraw  all or  any  portion  of its
investment at any time at net asset value.  Investors in the Portfolio will each
be liable for all obligations of the Portfolio. However, the risk of an investor
in the  Portfolio  incurring  financial  loss on  account of such  liability  is
limited  to  circumstances  in which  both  adequate  insurance  exists  and the
Portfolio itself is unable to meet its obligations.

         The Declaration of Trust provides that the Portfolio will terminate 120
days after the  complete  withdrawal  of any  investor in the  Portfolio  unless
either  the  remaining  investors,  by  unanimous  vote  at a  meeting  of  such
investors, or a majority of the Trustees of the Portfolio, by written instrument
consented to by all investors,  agree to continue the business of the Portfolio.
This  provision  is  consistent  with  the  treatment  of  the  Portfolio  as  a
partnership for federal income tax purposes.
   
         An interest in the Portfolio has no preemptive or conversion rights and
is fully paid and nonassessable, except as set forth above. The Portfolio is not
required and has no current intention to hold annual meetings of investors,  but
the Portfolio may hold special meetings of investors when in the judgment of the
Trustees it is necessary or  desirable to submit  matters for an investor  vote.
Changes in fundamental  policies or restrictions  will be submitted to investors
for  approval.  The  investment  objective  and  all  nonfundamental  investment
policies  of the  Portfolio  may be changed  by the  Trustees  of the  Portfolio
without obtaining the approval of the investors in the Portfolio. Investors have
under certain  circumstances  (e.g.,  upon application and submission of certain
specified  documents to the  Trustees by a specified  number of  investors)  the
right to  communicate  with other  investors  in  connection  with  requesting a
meeting of  investors  for the purpose of  removing  one or more  Trustees.  Any
Trustee may be removed by the  affirmative  vote of holders of two-thirds of the
interests in the Portfolio.  Upon liquidation of the Portfolio,  investors would
be entitled to share pro rata in the net assets of the  Portfolio  available for
distribution to investors.
    
         Information  regarding pooled investment  entities or funds that invest
in the Portfolio may be obtained by contacting Eaton Vance  Distributors,  Inc.,
24 Federal Street, Boston, MA 02110, (617) 482-8260.
   
         As of November 29, 1996, EV Traditional Worldwide Health Sciences Fund,
Inc.,  controlled the Portfolio by virtue of owning  approximately  88.0% of the
outstanding interests in the Portfolio.
    
         The net asset value of the  Portfolio is  determined  each day on which
the New York Stock  Exchange (the  "Exchange")  is open for trading  ("Portfolio
Business Day"). This determination is made each Portfolio Business Day as of the
close of regular  trading on the Exchange  (currently  4:00 p.m., New York time)
(the "Portfolio Valuation Time").

         Each investor in the  Portfolio may add to or reduce its  investment in
the Portfolio on each Portfolio Business Day as of the Portfolio Valuation Time.
The value of each  investor's  interest in the  Portfolio  will be determined by
multiplying the net asset value of the Portfolio by the  percentage,  determined
on the prior Portfolio  Business Day, which represented that investor's share of
the  aggregate  interest  in  the  Portfolio  on  such  day.  Any  additions  or
withdrawals,  which are to be effected on that day, will then be effected.  Each
investor's  percentage of the aggregate  interests in the Portfolio will then be
recomputed as the  percentage  equal to a fraction (i) the numerator of which is
the value of such  investor's  investment  in the  Portfolio  as of the close of
regular trading on the Exchange (normally 4:00 p.m., New York time), on such day
plus  or  minus,  as the  case  may  be,  that  amount  of any  additions  to or
withdrawals  from the  investor's  investment in the Portfolio  effected on such
day, and (ii) the  denominator  of which is the aggregate net asset value of the
Portfolio as of the close of such trading on such day plus or minus, as the case
may be, the amount of the net  additions to or  withdrawals  from the  aggregate
investment in the Portfolio by all investors in the Portfolio. The percentage so
determined  will  then be  applied  to  determine  the  value of the  investor's
interest in the Portfolio for the current Portfolio Business Day.

         The Portfolio  will allocate at least  annually among its investors its
net  investment  income,  net  realized  capital  gains,  and any other items of
income,  gain, loss,  deduction or credit. The Portfolio's net investment income
consists of all income accrued on the  Portfolio's  assets,  less all actual and
accrued  expenses of the  Portfolio,  determined  in accordance  with  generally
accepted accounting principles.

         Under  the  anticipated  method  of  operation  of the  Portfolio,  the
Portfolio  will not be subject to any federal income tax. (See Part B, Item 20.)
However,  each  investor in the  Portfolio  will take into account its allocable
share of the  Portfolio's  ordinary  income and capital gain in determining  its
federal income tax liability.  The determination of each such share will be made
in  accordance  with the  governing  instruments  of the  Portfolio,  which  are
intended  to  comply  with the  requirements  of the  Code  and the  regulations
promulgated thereunder.
   
         It is intended that the  Portfolio's  assets and income will be managed
in such a way that an  investor  in the  Portfolio  that  seeks to  qualify as a
regulated  investment  company  under  the  Code  will be able  to  satisfy  the
requirements for such qualification.
    
Item 7.  Purchase of Interests in the Portfolio

         Interests  in the  Portfolio  are issued  solely in  private  placement
transactions  that do not involve any  "public  offering"  within the meaning of
Section 4(2) of the 1933 Act. See "General Description of Registrant" above.

         An investment in the Portfolio  will be made without a sales load.  All
investments  received by the Portfolio will be effected as of the next Portfolio
Valuation  Time.  The net asset  value of the  Portfolio  is  determined  at the
Portfolio  Valuation Time on each Portfolio  Business Day. The Portfolio will be
closed for business and will not  determine its net asset value on the following
business holidays:  New Year's Day, Presidents' Day, Good Friday,  Memorial Day,
Independence Day, Labor Day, Thanksgiving Day and Christmas Day. The Portfolio's
net asset value is computed in accordance  with  procedures  established  by the
Portfolio's Trustees.

         The  Portfolio's  net asset value is  determined  by IBT Fund  Services
(Canada) Inc. (as agent for the Portfolio)  based on market or fair value in the
manner authorized by the Trustees of the Portfolio,  with special provisions for
valuing debt obligations,  short-term  investments,  foreign securities,  direct
investments,  hedging instruments and assets not having readily available market
quotations,  if any.  The  net  asset  value  is  computed  by  subtracting  the
liabilities  of the Portfolio  from the value of its total  assets.  For further
information  regarding the valuation of the Portfolio's assets, see Part B, Item
19.

         There is no minimum initial or subsequent  investment in the Portfolio.
The Portfolio  reserves the right to cease accepting  investments at any time or
to reject any investment order.
   
         The placement  agent for the  Portfolio is EVD. The principal  business
address of EVD is 24 Federal Street,  Boston,  Massachusetts 02110. EVD receives
no  compensation  from the Portfolio for serving as the placement  agent for the
Portfolio.
    
Item 8.  Redemption or Decrease of Interest

         An  investor  in the  Portfolio  may  withdraw  all of  (redeem) or any
portion of (decrease)  its interest in the Portfolio if a withdrawal  request in
proper form is furnished by the investor to the Portfolio.  All withdrawals will
be  effected  as of  the  next  Portfolio  Valuation  Time.  The  proceeds  of a
withdrawal will be paid by the Portfolio  normally on the Portfolio Business Day
the  withdrawal is effected,  but in any event within seven days.  The Portfolio
reserves the right to pay the proceeds of a withdrawal  (whether a redemption or
decrease) by a distribution in kind of portfolio  securities  (instead of cash).
The  securities  so  distributed  would be  valued  at the same  amount  as that
assigned to them in  calculating  the net asset value for the interest  (whether
complete or partial) being withdrawn.  If an investor received a distribution in
kind upon such withdrawal,  the investor could incur brokerage and other charges
in  converting  the  securities  to  cash.  The  Portfolio  has  filed  with the
Securities and Exchange Commission (the "Commission") a notification of election
on Form N-18F-1  committing to pay in cash all requests for  withdrawals  by any
investor,  limited in amount  with  respect to such  investor  during any 90 day
period to the  lesser of (a)  $250,000  or (b) 1% of the net asset  value of the
Portfolio at the beginning of such period.

         Investments in the Portfolio may not be transferred.

         The right of any  investor  to  receive  payment  with  respect  to any
withdrawal may be suspended or the payment of the withdrawal  proceeds postponed
during  any period in which the  Exchange  is closed  (other  than  weekends  or
holidays) or trading on the Exchange is restricted  or, to the extent  otherwise
permitted  by the 1940 Act, if an emergency  exists,  or during any other period
permitted by order of the Commission for the protection of investors.

Item 9.  Pending Legal Proceedings

         Not applicable.


<PAGE>








                                     PART B

Item 10.  Cover Page

         Not applicable.

Item 11.  Table of Contents
   
                                                                           Page
         General Information and History..........................          B-1
         Investment Objectives and Policies.......................          B-1
         Management of the Portfolio..............................          B-9
         Control Persons and Principal Holder of Securities.......         B-12
         Investment Advisory and Other Services...................         B-12
         Brokerage Allocation and Other Practices................          B-15
         Capital Stock and Other Securities......................          B-17
         Purchase, Redemption and Pricing of Securities..........          B-19
         Tax Status..............................................          B-20
         Underwriters............................................          B-22
         Calculation of Performance Data.........................          B-22
         Financial Statements.....................................         B-22
    
Item 12.  General Information and History

     Effective  June 24,  1996,  the  Portfolio's  name was changed from "Global
Health Sciences Portfolio" to "Worldwide Health Sciences Portfolio."

Item 13.  Investment Objectives and Policies

         Part A contains additional  information about the investment  objective
and policies of Worldwide Health Sciences Portfolio.  This Part B should be read
in  conjunction  with  Part A.  Capitalized  terms  used in this  Part B and not
otherwise defined have the meanings given them in Part A.

Foreign Investments.  Under normal market conditions,  the Portfolio will invest
in  securities  of  issuers  located  in at  least  three  different  countries.
Investing in securities issued by companies whose principal business  activities
are  outside  the United  States may  involve  significant  risks not present in
domestic  investments.  For example,  there is generally less publicly available
information  about  foreign  companies,  particularly  those not  subject to the
disclosure  and reporting  requirements  of the U.S.  securities  laws.  Foreign
issuers are generally not bound by uniform accounting,  auditing,  and financial
reporting  requirements and standards of practice comparable to those applicable
to domestic issuers.  Investments in foreign securities also involve the risk of
possible  adverse  changes  in  investment  or  exchange  control   regulations,
expropriation  or confiscatory  taxation,  limitation on the removal of funds or
other assets of the Portfolio,  political or financial instability or diplomatic
and other developments which could affect such investments.  Further,  economies
of  particular  countries  or  areas  of  the  world  may  differ  favorably  or
unfavorably  from the economy of the United States.  It is  anticipated  that in
most cases the best available market for foreign securities will be on exchanges
or in  over-the-counter  markets located  outside of the United States.  Foreign
stock markets, while growing in volume and sophistication,  are generally not as
developed as those in the United States,  and securities of some foreign issuers
(particularly those located in developing countries) may be less liquid and more
volatile than  securities of comparable  U.S.  companies.  In addition,  foreign
brokerage commissions are generally higher than commissions on securities traded
in the  United  States  and may be  non-negotiable.  In  general,  there is less
overall  governmental  supervision and regulation of foreign securities markets,
broker-dealers, and issuers than in the United States.

Foreign Currency Transactions.  Because investments in companies whose principal
business  activities are located outside of the United States will frequently be
denominated  in foreign  currencies,  and because  assets of the  Portfolio  may
temporarily be held in bank deposits in foreign currencies during the completion
of investment programs,  the value of the assets of the Portfolio as measured in
U.S.  dollars may be affected  favorably  or  unfavorably  by changes in foreign
currency  exchange rates and exchange  control  regulations.  Currency  exchange
rates can also be  affected  unpredictably  by  intervention  by U.S. or foreign
governments  or central  banks,  or the  failure to  intervene,  or by  currency
controls or political  developments  in the U.S. or abroad.  The  Portfolio  may
conduct its foreign currency exchange  transactions on a spot (i.e., cash) basis
at the spot rate prevailing in the foreign  currency  exchange market or through
entering into swaps, forward contracts,  options or futures on currency. On spot
transactions,  foreign exchange dealers do not charge a fee for conversion,  but
they do realize a profit  based on the  difference  (the  "spread")  between the
prices at which they are buying and selling various  currencies.  Thus, a dealer
may  offer to sell a  foreign  currency  to the  Portfolio  at one  rate,  while
offering a lesser rate of exchange  should the  Portfolio  desire to resell that
currency to the dealer.

Emerging  Companies.  The investment risk associated with emerging  companies is
higher than that normally  associated  with larger,  older  companies due to the
greater  business  risks  associated  with small size,  the  relative age of the
company,  limited  product  lines,   distribution  channels  and  financial  and
managerial  resources.  Further,  there is  typically  less  publicly  available
information concerning smaller companies than for larger, more established ones.
The securities of small companies are often traded only over-the-counter and may
not be traded  in the  volumes  typical  of  trading  on a  national  securities
exchange.  As a result, in order to sell this type of holding, the Portfolio may
need to discount the securities  from recent prices or dispose of the securities
over a long  period of time.  The  prices of this type of  security  may be more
volatile  than those of larger  companies  which are often  traded on a national
securities exchange.

Currency  Swaps.  Currency  swaps require  maintenance  of a segregated  account
described under "Asset Coverage for Derivative Instruments" below. The Portfolio
will not enter into any currency swap unless the credit quality of the unsecured
senior  debt  or  the  claims-paying  ability  of the  other  party  thereto  is
considered to be investment  grade by the Adviser.  If there is a default by the
other party to such a transaction,  the Portfolio will have contractual remedies
pursuant to the agreements related to the transaction. The swap market has grown
substantially  in recent  years  with a large  number  of banks  and  investment
banking firms acting both as  principals  and as agents  utilizing  standardized
swap documentation. As a result, the swap market has become relatively liquid in
comparison  with the markets for other similar  instruments  which are traded in
the interbank market.

Forward Foreign  Currency  Exchange  Transactions.  The Portfolio may enter into
forward foreign currency  exchange  contracts in several  circumstances.  First,
when the Portfolio enters into a contract for the purchase or sale of a security
denominated in a foreign currency, or when the Portfolio anticipates the receipt
in a foreign currency of dividend or interest  payments on such a security which
it holds,  the  Portfolio  may desire to "lock in" the U.S.  dollar price of the
security or the U.S. dollar equivalent of such dividend or interest payment,  as
the case may be. By entering  into a forward  contract for the purchase or sale,
for a fixed amount of dollars, of the amount of foreign currency involved in the
underlying transactions, the Portfolio will attempt to protect itself against an
adverse  change in the  relationship  between  the U.S.  dollar and the  subject
foreign  currency  during the period  between the date on which the  security is
purchased or sold, or on which the dividend or interest payment is declared, and
the date on which such payments are made or received.

         Additionally,  when  management  of the  Portfolio  believes  that  the
currency  of a  particular  foreign  country  may suffer a  substantial  decline
against the U.S.  dollar,  it may enter into a forward  contract to sell,  for a
fixed amount of dollars, the amount of foreign currency  approximating the value
of  some or all of the  securities  held by the  Portfolio  denominated  in such
foreign  currency.  The precise matching of the forward contract amounts and the
value of the  securities  involved  will not  generally be possible  because the
future  value  of  such  securities  in  foreign  currencies  will  change  as a
consequence  of market  movements in the value of those  securities  between the
date on which the contract is entered into and the date it matures.  The precise
projection  of  short-term  currency  market  movements  is  not  possible,  and
short-term hedging provides a means of fixing the dollar value of only a portion
of the Portfolio's foreign assets.

Special Risks  Associated  With Currency  Transactions.  Transactions in forward
contracts, as well as futures and options on foreign currencies,  are subject to
the  risk  of  governmental  actions  affecting  trading  in or  the  prices  of
currencies underlying such contracts,  which could restrict or eliminate trading
and could have a substantial  adverse  effect on the value of positions  held by
the  Portfolio.  In  addition,  the value of such  positions  could be adversely
affected by a number of other complex political and economic factors  applicable
to the countries issuing the underlying currencies.

         Furthermore,  unlike trading in most other types of instruments,  there
is no systematic  reporting of last sale information with respect to the foreign
currencies  underlying  forward contracts,  futures contracts and options.  As a
result, the available  information on which the Portfolio's trading systems will
be based may not be as complete as the  comparable  data on which the  Portfolio
makes  investment and trading  decisions in connection with securities and other
transactions.  Moreover,  because  the  foreign  currency  market  is a  global,
twenty-four  hour  market,  events  could occur on that market which will not be
reflected in the forward,  futures or options  markets until the following  day,
thereby  preventing  the  Portfolio  from  responding to such events in a timely
manner.

         Settlements of over-the-counter forward contracts or of the exercise of
foreign  currency  options  generally must occur within the country  issuing the
underlying currency,  which in turn requires parties to such contracts to accept
or make  delivery of such  currencies  in  conformity  with any United States or
foreign  restrictions  and  regulations  regarding  the  maintenance  of foreign
banking relationships, fees, taxes or other charges.

         Unlike currency futures contracts and exchange-traded  options, options
on foreign  currencies and forward  contracts are not traded on contract markets
regulated by the Commodities  Futures Trading  Commission  ("CFTC") or (with the
exception  of certain  foreign  currency  options) the  Securities  and Exchange
Commission ("Commission").  To the contrary, such instruments are traded through
financial  institutions  acting as market-makers.  (Foreign currency options are
also  traded  on  the   Philadelphia   Stock  Exchange   subject  to  Commission
regulation). In an over-the-counter trading environment, many of the protections
associated with  transactions  on exchanges will not be available.  For example,
there are no daily price fluctuation  limits, and adverse market movements could
therefore  continue to an unlimited  extent over a period of time.  Although the
purchaser  of an option  cannot  lose more than the amount of the  premium  plus
related transaction costs, this entire amount could be lost. Moreover, an option
writer could lose amounts  substantially in excess of its initial investment due
to the margin and collateral requirements associated with such option positions.
Similarly,  there is no limit on the  amount  of  potential  losses  on  forward
contracts to which the Portfolio is a party.

         In  addition,  over-the-counter  transactions  can only be entered into
with a financial institution willing to take the opposite side, as principal, of
the Portfolio's  position  unless the institution  acts as broker and is able to
find  another  counterparty  willing  to  enter  into the  transaction  with the
Portfolio.  Where no such counterparty is available,  it will not be possible to
enter into a desired  transaction.  There also may be no liquid secondary market
in the trading of over-the-counter contracts, and the Portfolio may be unable to
close out options purchased or written, or forward contracts entered into, until
their exercise, expiration or maturity. This in turn could limit the Portfolio's
ability  to  realize  profits or to reduce  losses on open  positions  and could
result in greater losses.

         Furthermore,  over-the-counter  transactions  are  not  backed  by  the
guarantee of an exchange's clearing corporation. The Portfolio will therefore be
subject  to the  risk  of  default  by,  or the  bankruptcy  of,  the  financial
institution  serving as its counterparty.  One or more of such institutions also
may decide to discontinue  its role as  market-maker  in a particular  currency,
thereby  restricting  the  Portfolio's  ability  to enter into  desired  hedging
transactions.  The Portfolio will enter into over-the-counter  transactions only
with parties whose  creditworthiness has been reviewed and found satisfactory by
the Adviser.

         The  purchase and sale of  exchange-traded  foreign  currency  options,
however,  are  subject to the risks of the  availability  of a liquid  secondary
market described above, as well as the risks regarding adverse market movements,
margining  of  options  written,  the  nature of the  foreign  currency  market,
possible  intervention  by  governmental  authorities  and the  effect  of other
political and economic events. In addition,  exchange-traded  options on foreign
currencies involve certain risks not presented by the  over-the-counter  market.
For example,  exercise and  settlement of such options must be made  exclusively
through the Options Clearing Corporation ("OCC"),  which has established banking
relationships in applicable foreign countries for this purpose. As a result, the
OCC may, if it determines that foreign governmental  restrictions or taxes would
prevent the orderly  settlement of foreign currency option  exercises,  or would
result  in undue  burdens  on the OCC or its  clearing  member,  impose  special
procedures  for  exercise  and  settlement,  such as  technical  changes  in the
mechanics of delivery of  currency,  the fixing of dollar  settlement  prices of
prohibitions on exercise.

Risks  Associated  With  Derivative  Instruments.  Entering  into  a  derivative
instrument  involves a risk that the  applicable  market  will move  against the
Portfolio's  position and that the Portfolio  will incur a loss.  For derivative
instruments other than purchased options, this loss may exceed the amount of the
initial  investment  made or the premium  received by the Portfolio.  Derivative
instruments  may sometimes  increase or leverage the  Portfolio's  exposure to a
particular market risk. Leverage enhances the Portfolio's  exposure to the price
volatility of derivative  instruments it holds. The Portfolio's success in using
derivative  instruments to hedge portfolio assets depends on the degree of price
correlation between the derivative  instruments and the hedged asset.  Imperfect
correlation  may  be  caused  by  several  factors,  including  temporary  price
disparities among the trading markets for the derivative instrument,  the assets
underlying the derivative instrument and the Portfolio assets.  Over-the-counter
("OTC")  derivative  instruments  involve  an  enhanced  risk that the issuer or
counterparty will fail to perform its contractual  obligations.  Some derivative
instruments  are not readily  marketable  or may become  illiquid  under adverse
market conditions. In addition, during periods of market volatility, a commodity
exchange  may  suspend  or  limit  trading  in  an  exchange-traded   derivative
instrument,  which may make the contract  temporarily  illiquid and difficult to
price.  Commodity  exchanges may also establish  daily limits on the amount that
the price of a futures  contract  or futures  option can vary from the  previous
day's settlement price.  Once the daily limit is reached,  no trades may be made
that day at the price  beyond the limit.  This may  prevent the  Portfolio  from
closing out positions and limiting its losses. The staff of the Commission takes
the position that  purchased  OTC options,  and assets used as cover for written
OTC options,  are subject to the Portfolio's 15% limit on illiquid  investments.
However, with respect to options written with primary dealers in U.S. Government
securities pursuant to an agreement requiring a closing purchase  transaction at
a formula  price,  the amount of  illiquid  securities  may be  calculated  with
reference  to the  formula  price.  The  Portfolio's  ability to  terminate  OTC
derivative  instruments may depend on the cooperation of the  counterparties  to
such contracts.  For thinly traded  derivative  instruments,  the only source of
price quotations may be the selling dealer or counterparty. In addition, certain
provisions of the Internal Revenue Code of 1986, as amended ("Code"),  limit the
extent to which the Portfolio may purchase and sell derivative instruments.  The
Portfolio will engage in transactions  in futures  contracts and related options
only to the extent such transactions are consistent with the requirements of the
Code for maintaining  the  qualification  of each of the Portfolio's  investment
company  investors  as a regulated  investment  company  for federal  income tax
purposes. See "Tax Status."
   
    

Limitations on Futures Contracts and Options.  If the Portfolio has not complied
with the 5% CFTC  test set  forth in the  Fund's  prospectus,  to  evidence  its
hedging intent,  the Portfolio  expects that, on 75% or more of the occasions on
which it takes a long  futures  or  option  on  futures  position,  it will have
purchased or will be in the process of purchasing, equivalent amounts of related
securities  at the time when the  futures or  options  position  is closed  out.
However,  in particular  cases,  when it is  economically  advantageous  for the
Portfolio to do so, a long futures or options  position may be terminated (or an
option may expire) without a corresponding purchase or securities.

         The Portfolio may enter into futures contracts,  and options on futures
contracts, traded on an exchange regulated by the CFTC and on foreign exchanges,
but,  with respect to foreign  exchange-traded  futures  contracts an options on
such futures contracts, only if the Adviser determines that trading on each such
foreign  exchange does not subject the Portfolio to risks,  including credit and
liquidity  risks,  that are materially  greater than the risks  associated  with
training on CFTC-regulated exchanges.

         In order to hedge its current or anticipated  portfolio positions,  the
Portfolio may use futures  contracts on  securities  held in its portfolio or on
securities with  characteristics  similar to those of the securities held by the
Portfolio.  If, in the opinion of the Adviser,  there is a sufficient  degree of
correlation  between price trends for the  securities  held by the Portfolio and
futures contracts based on other financial  instruments,  securities  indices or
other indices,  the Portfolio may also enter into such futures contracts as part
of its hedging strategy.

         All call and put options on securities written by the Portfolio will be
covered.  This means that, in the case of a call option,  the Portfolio will own
the securities  subject to the call option or an offsetting  call option so long
as the call option is  outstanding.  In the case of a put option,  the Portfolio
will own an offsetting put option or will have deposited with its custodian cash
or liquid  securities  with a value at least equal to the exercise  price of the
put  option.  The  Portfolio  may only write a put option on a security  that it
intends ultimately to acquire for its investment portfolio.

Repurchase  Agreements.  Under  a  repurchase  agreement  the  Portfolio  buys a
security at one price and  simultaneously  promises  to sell that same  security
back to the seller at a higher price. At no time will the Portfolio  commit more
than 15% of its net assets to  repurchase  agreements  which mature in more than
seven days and other illiquid securities.  The Portfolio's repurchase agreements
will  provide  that  the  value  of the  collateral  underlying  the  repurchase
agreement will always be at least equal to the repurchase  price,  including any
accrued  interest  earned  on the  repurchase  agreement,  and will be marked to
market daily.

Reverse Repurchase  Agreements.  The Portfolio may enter into reverse repurchase
agreements.  Under a reverse  repurchase  agreement,  the Portfolio  temporarily
transfers  possession of a portfolio instrument to another party, such as a bank
or broker-dealer,  in return for cash. At the same time, the Portfolio agrees to
repurchase the  instrument at an agreed upon time  (normally  within seven days)
and price,  which reflects an interest  payment.  The Portfolio  expects that it
will enter into reverse repurchase agreements when it is able to invest the cash
so  acquired  at a rate  higher  than the  cost of the  agreement,  which  would
increase the income earned by the Portfolio. The Portfolio could also enter into
reverse  repurchase  agreements as a means of raising cash to satisfy redemption
requests without the necessity of selling portfolio assets.

         When the  Portfolio  enters into a reverse  repurchase  agreement,  any
fluctuations in the market value of either the securities transferred to another
party or the  securities in which the proceeds may be invested  would affect the
market value of the  Portfolio's  assets.  As a result,  such  transactions  may
increase fluctuations in the market value of the Portfolio's assets. While there
is a risk that large  fluctuations in the market value of the Portfolio's assets
could affect the  Portfolio's  net asset value,  this risk is not  significantly
increased by entering into reverse repurchase agreements,  in the opinion of the
Adviser.  Because  reverse  repurchase  agreements  may be  considered to be the
practical equivalent of borrowing funds, they constitute a form of leverage.  If
the Portfolio reinvests the proceeds of a reverse repurchase agreement at a rate
lower than the cost of the agreement, entering into the agreement will lower the
Portfolio's yield.

         At all times that a reverse  repurchase  agreement is outstanding,  the
Portfolio  will  maintain  cash  or  high  grade  liquid  debt  securities  in a
segregated  account  at its  custodian  bank with a value at least  equal to its
obligation  under  the  agreement.  Securities  and  other  assets  held  in the
segregated  account may not be sold while the reverse  repurchase  agreement  is
outstanding,  unless other suitable  assets are  substituted.  While the Adviser
does not  consider  reverse  repurchase  agreements  to  involve  a  traditional
borrowing  of money,  reverse  repurchase  agreements  will be  included  in the
Portfolio's borrowing restrictions.

Portfolio  Turnover.  The  Portfolio  cannot  accurately  predict its  portfolio
turnover  rate,  but it is  anticipated  that  the  annual  turnover  rate  will
generally not exceed 100% (excluding turnover of securities having a maturity of
one year or less). A 100% annual turnover rate would occur, for example,  if all
the  securities in the  portfolio  were replaced once in a period of one year. A
high turnover rate (100% or more)  necessarily  involves greater expenses to the
Portfolio.  The Portfolio  engages in portfolio  trading  (including  short-term
trading)  if it believes  that a  transaction  including  all costs will help in
achieving its investment  objective either by increasing  income or by enhancing
the Portfolio's net asset value. Short-term trading may be advisable in light of
a change  in  circumstances  of a  particular  company  or  within a  particular
industry, or in light of general market, economic or political conditions.  High
portfolio  turnover  may also  result  in the  realization  of  substantial  net
short-term capital gains.

Lending Portfolio  Securities.  If the Adviser decides to make securities loans,
the Portfolio may seek to increase its income by lending portfolio securities to
broker-dealers or other institutional  borrowers. The financial condition of the
borrower  will be monitored by the Adviser on an ongoing  basis.  The  Portfolio
would  continue to receive the  equivalent of the interest or dividends  paid by
the issuer on the  securities  loaned and would also  receive a fee, or all or a
portion of the interest on investment  of the  collateral.  The Portfolio  would
have the right to call a loan and obtain the securities loaned at any time on up
to five business  days' notice.  The Portfolio  would not have the right to vote
any  securities  having voting rights during the existence of a loan,  but could
call the loan in  anticipation of an important vote to be taken among holders of
the  securities  or the  giving or  withholding  of their  consent on a material
matter  affecting the investment.  Securities  lending  involves  administrative
expenses  including  finders'  fees. If the Adviser  decides to make  securities
loans,  it is intended that the value of the securities  loaned would not exceed
1/3 of the Portfolio's total assets. As of the present time, the Trustees of the
Portfolio have not made a determination to engage in this activity,  and have no
present intention of making such a determination during the current fiscal year.
   
Asset  Coverage   Requirements.   Transactions   involving  reverse   repurchase
agreements,  the lending of Portfolio  securities or forward contracts,  futures
contracts  and options  (other than options that the  Portfolio  has  purchased)
expose the Portfolio to an obligation to another  party.  The Portfolio will not
enter  into  any such  transactions  unless  it owns  either  (1) an  offsetting
("covered")  position in  securities,  currencies,  or other  options or futures
contracts or forward  contracts,  or (2) cash,  receivables  and short-term debt
securities  with a  value  sufficient  at  all  times  to  cover  its  potential
obligations not covered as provided in (1) above. The Portfolio will comply with
Commission  guidelines  regarding  cover  for  these  instruments  and,  if  the
guidelines  so require,  set aside cash,  or liquid  securities  in a segregated
account with its  custodian in the  prescribed  amount.  The  securities  in the
segregated account will be market to market daily.
    
   
         Assets  used as cover or held in a  segregated  account  cannot be sold
while the position requiring coverage or segregation is outstanding, unless they
are replaced with other  appropriate  assets.  As a result,  the commitment of a
large portion of the  Portfolio's  assets to cover or segregated  accounts could
impede  portfolio  management  or the  Portfolio's  ability  to meet  redemption
requests or other current obligations.
    
Investment Restrictions

         The Portfolio has adopted the following  investment  restrictions which
may not be changed  without the  approval  of the holders of a "majority  of the
outstanding  voting  securities" of the Portfolio,  which as used in this Part B
means the lesser of (a) 67% or more of the outstanding  voting securities of the
Portfolio  present or  represented  by proxy at a meeting if the holders of more
than 50% of the  outstanding  voting  securities of the Portfolio are present or
represented  at the  meeting  or (b)  more  than 50% of the  outstanding  voting
securities  of the  Portfolio.  The  term  "voting  securities"  as used in this
paragraph has the same meaning as in the 1940 Act.
As a matter of fundamental policy, the Portfolio may not:

     (1) Borrow  money or issue  senior  securities  except as  permitted by the
         Investment Company Act of 1940;

         (2) Purchase any  securities  on margin (but the  Portfolio  may obtain
         such  short-term  credits  as may be  necessary  for the  clearance  of
         purchases and sales of securities);

         (3)  Underwrite securities of other issuers;

         (4) Invest in real estate  including  interests in real estate  limited
         partnerships  (although it may purchase and sell  securities  which are
         secured by real estate and securities of companies which invest or deal
         in real estate) or purchase or sell commodities or commodity  contracts
         with respect to physical commodities;

         (5) Make  loans to any  person  except by (a) the  acquisition  of debt
         securities  and  making  portfolio   investments,   (b)  entering  into
         repurchase agreements and (c) lending portfolio securities;

         (6) With respect to 75% of its total assets, invest more than 5% of its
         total  assets  (taken at current  value) in the  securities  of any one
         issuer, or invest in more than 10% of the outstanding voting securities
         of any one issuer,  except obligations issued or guaranteed by the U.S.
         Government,  its agencies or instrumentalities and except securities of
         other investment companies; or

         (7) Invest in the  securities of any one  industry,  except the medical
         research  and health care  industry  (and except  securities  of health
         sciences  companies  or  securities  issued or  guaranteed  by the U.S.
         Government,  its agencies or  instrumentalities)  if as a result 25% or
         more  of  the  Portfolio's  total  assets  would  be  invested  in  the
         securities of such industry.

         Notwithstanding   the  investment  policies  and  restrictions  of  the
Portfolio,  the  Portfolio  may invest part of its assets in another  investment
company consistent with the 1940 Act.
   
        The  Portfolio  has adopted  the  following  nonfundamental  investment
policies  which may be changed by the  Portfolio  without  the  approval  of its
investors.  The  Portfolio may not (i) invest more than 15% of its net assets in
investments which are not readily marketable,  including  repurchase  agreements
with  remaining  maturities  in excess of seven days and  restricted  securities
(restricted  securities  for the  purposes  of this  limitation  do not  include
securities eligible for resale pursuant to Rule 144A under the Securities Act of
1933 and commercial  paper issued  pursuant to Section 4(2) of said Act that the
Board of Trustees of the Portfolio,  or its delegate,  determines to be liquid);
(ii)  invest  in  warrants  if as a  result  more  than 2% of the  value  of the
Portfolio's total assets would be invested in warrants which are not listed on a
recognized stock exchange, or more than 5% of the Portfolio's total assets would
be invested in warrants  regardless of whether listed on such  exchanges;  (iii)
purchase  or retain  the  securities  of any issuer if to the  knowledge  of the
Portfolio any officer, director or trustee of the Portfolio or of its investment
adviser own  beneficially  more than 1/2 of 1% of the outstanding  securities of
such issuer and together they own beneficially more than 5% of the securities of
such issuer;  (iv) invest in companies for the purpose of exercising  control or
management;  or (v)  invest in or sell put  options,  call  options,  straddles,
spreads or any combination thereof,  except that the Portfolio may write covered
call options or enter into  closing  purchase  transactions  and except that the
Portfolio may enter into futures contracts and related options.
    
         Whenever an investment  policy or investment  restriction  set forth in
Part A or this Part B states a maximum percentage of assets that may be invested
in any  security  or  other  asset  or  describes  a  policy  regarding  quality
standards,   such   percentage   limitation  or  standard  shall  be  determined
immediately  after  and as a  result  of the  Portfolio's  acquisition  of  such
security or other asset.  Accordingly,  any later increase or decrease resulting
from a change in values, assets or other circumstances,  other than a subsequent
rating change below investment  grade made by a rating service,  will not compel
the  Portfolio to dispose of such security or other asset.  Nevertheless,  under
normal market  conditions  the Portfolio  must take actions  necessary to comply
with its  policy  of  investing  at least  65% of its  total  assets  in  equity
securities of health science companies.  Moreover,  the Portfolio must always be
in compliance with the borrowing policy set forth above.
   
    

Item 14.  Management of the Portfolio

The  Portfolio's  Trustees and officers are listed  below.  Except as indicated,
each  individual  has held the office shown or other offices in the same company
for the last five years.  Unless  otherwise  noted, the business address of each
Trustee and officer is 24 Federal Street, Boston,  Massachusetts 02110, which is
also the address of Eaton Vance  Management  ("Eaton  Vance");  of Eaton Vance's
wholly-owned  subsidiary,  Boston  Management  and  Research  ("BMR");  of Eaton
Vance's parent, Eaton Vance Corp. ("EVC");  and of Eaton Vance's trustee,  Eaton
Vance,  Inc. ("EV").  Eaton Vance and EV are both  wholly-owned  subsidiaries of
EVC. Those Trustees who are "interested persons" of the Portfolio,  Eaton Vance,
BMR,  EVC,  EV or the  Adviser,  as  defined  in the 1940 Act by virtue of their
affiliation with any one or more of the Portfolio,  Eaton Vance, BMR, EVC, EV or
the Adviser, are indicated by an asterisk (*).

TRUSTEES
   
JAMES B. HAWKES (55), President and Trustee*
President  of  Eaton  Vance,  BMR,  EVC and EV,  and a  Director  of EVC and EV.
Director or Trustee and officer of various investment companies managed by Eaton
Vance or BMR.
    
   
     DONALD R.  DWIGHT  (65),  Trustee  President  of Dwight  Partners,  Inc. (a
corporate  relations and  communications  company) founded in 1988.  Director or
Trustee of various investment  companies managed by Eaton Vance or BMR. Address:
Clover Mill Lane, Lyme, New Hampshire 03768.
    
     SAMUEL L. HAYES, III (61),  Trustee Jacob H. Schiff Professor of Investment
Banking  at  Harvard  University  Graduate  School of  Business  Administration.
Director or Trustee of various  investment  companies  managed by Eaton Vance or
BMR. Address:  Harvard  University  Graduate School of Business  Administration,
Soldiers Field Road, Boston, Massachusetts 02134
   
     NORTON H.  REAMER  (61),  Trustee  President  and  Director,  United  Asset
Management  Corporation  (a  holding  company  owning  institutional  management
firms). Chairman,  President and Director, UAM Funds (mutual funds). Director or
Trustee of various investment  companies managed by Eaton Vance or BMR. Address:
One International Place, Boston, Massachusetts 02110
    
   
     JOHN L. THORNDIKE (70), Trustee Director,  Fiduciary Company  Incorporated.
Director or Trustee of various  investment  companies  managed by Eaton Vance or
BMR. Address: 175 Federal Street, Boston, Massachusetts 02110
    
JACK L. TREYNOR (66), Trustee
Investment Adviser and Consultant.  Director or Trustee of various investment
companies managed by Eaton Vance or BMR.
Address:  504 Via Almar, Palos Verdes Estates, California  90274

OFFICERS
   
     SAMUEL D. ISALY (51),  Vice  President  President  of Mehta and Isaly Asset
Management,  Inc. since 1989;  Senior Vice President of S.G. Warburg & Co., Inc.
from 1986 through  1989;  and  President of Gramercy  Associates,  a health care
industry consulting firm, from 1983 through 1986. Address: Mehta and Isaly Asset
Management, Inc., 41 Madison Avenue, 40th Floor, New York, New York 10010.
    
   

JAMES L. O'CONNOR (51), Treasurer
Vice  President  of Eaton  Vance,  BMR and EV.  Officer  of  various  investment
companies managed by Eaton Vance or BMR.
    
   

THOMAS OTIS (65), Secretary
Vice President and Secretary of Eaton Vance, BMR, EVC and EV. Officer of various
investment companies managed by Eaton Vance or BMR.
    
   
JANET E. SANDERS (61),  Assistant  Secretary and Assistant  Treasurer  Vice
President of Eaton Vance,  BMR and EV. Officer of various  investment  companies
managed by Eaton Vance or BMR.
    
   
A. JOHN MURPHY (34), Assistant Secretary
Assistant  Vice  President  of BMR,  Eaton  Vance  and EV since  March 1,  1994;
employee of Eaton Vance since March  1993.  State  Regulations  Supervisor,  The
Boston Company  (1991-1993) and Registration  Specialist,  Fidelity Management &
Research Co.  (1986-1991).  Officer of various  investment  companies managed by
Eaton Vance or BMR.
    
   
ERIC G. WOODBURY (39), Assistant Secretary
Vice  President  of BMR,  Eaton  Vance  and EV since  February  1993;  formerly,
associate  attorney  at Dechert  Price & Rhoads  and  Gaston & Snow.  Officer of
various investment companies managed by Eaton Vance or BMR.
    
   
         Messrs.  Hayes  (Chairman),  Reamer and  Thorndike  are  members of the
Special Committee of the Board of Trustees of the Portfolio.  The purpose of the
Special Committee is to consider,  evaluate and make recommendations to the full
Board of Trustees  concerning  (i) all  contractual  arrangements  with  service
providers to the Portfolio,  including investment  advisory,  custodial and fund
accounting  services,  and (ii) all other  matters in which  Eaton  Vance or its
affiliates  has any actual or potential  conflict of interest with the Portfolio
or its interestholders.
    
   
         The  Nominating  Committee is  compromised of four Trustees who are not
"interested  persons" as that term is defined under the 1940 Act ("noninterested
Trustees").  The  Committee  has  four-year  staggered  terms,  with one  member
rotating off the  Committee to be replaced by another  noninterested  Trustee of
the  Portfolio.  The  purpose  of the  Committee  is to  recommend  to the Board
nominees for the position of noninterested Trustee and to assure that at least a
majority  of the  Board  of  Trustees  is  independent  of Eaton  Vance  and its
affiliates.
    
         Messrs.  Treynor  (Chairman)  and  Dwight  are  members  of  the  Audit
Committee  of the Board of Trustees.  The Audit  Committee's  functions  include
making   recommendations   to  the  Trustees  regarding  the  selection  of  the
independent  certified public  accountants,  and reviewing with such accountants
and the  Treasurer of the  Portfolio  matters  relative to trading and brokerage
policies and  practices,  accounting  and  auditing  practices  and  procedures,
accounting records, internal accounting controls, and the functions performed by
the custodian and transfer agent of the Portfolio.
   
         The fees and  expenses  of those  Trustees  who are not  members of the
Eaton Vance organization (the noninterested Trustees) are paid by the Portfolio.
(The  Trustees  who are  members  of the Eaton  Vance  organization  receive  no
compensation from the Portfolio.) For the fiscal year ending August 31, 1997, it
is estimated  that the  noninterested  Trustees of the  Portfolio  will earn the
following  compensation in their  capacities as Trustees of the Portfolio,  and,
during the year ended  September  30, 1996,  the  noninterested  Trustees of the
Portfolio  earned the following  compensation in their capacities as Trustees of
the funds in the Eaton Vance fund complex(1):
    
                          Estimated
                          Aggregate
                          Compensation               Total Compensation
Name                      from Portfolio             From Fund Complex
- ----                      --------------             --------------------
   
Donald R.
Dwight                  $ 256                          $142,500(2)

Samuel L.
Hayes, III                325                          153,750(3)

Norton H.
Reamer                    308                          142,500

John L.
Thorndike                 338                          147,500

Jack L.
Treynor                   318                          147,500
    
   
(1)      The Eaton Vance fund complex consists of 228 registered investment
         companies or series thereof.
(2)      Includes $42,500 of deferred compensation.
(3)      Includes $37,500 of deferred compensation.
    
   
         Trustees of the  Portfolio who are not  affiliated  with the Adviser or
Eaton Vance may elect to defer  receipt of all or a  percentage  of their annual
fees in accordance with the terms of a Trustees Deferred  Compensation Plan (the
"Plan"). Under the Plan, an eligible Trustee may elect to have his deferred fees
invested by the  Portfolio in the shares of one or more funds in the Eaton Vance
Family of Funds,  and the  amount  paid to the  Trustees  under the Plan will be
determined based upon the performance of such investments. Deferral of Trustees'
fees  in  accordance  with  the  Plan  will  have  a  negligible  effect  on the
Portfolio's assets, liabilities, and net income per share, and will not obligate
the Portfolio to retain the services of any Trustee or obligate the Portfolio to
pay any particular level of compensation to the Trustee.  The Portfolio does not
have a  retirement  plan  for  its  Trustees.  The  Portfolio  does  not  have a
retirement plan for its Trustees.
    
         The  Portfolio's  Declaration  of Trust provides that it will indemnify
its  Trustees  and  officers  against   liabilities  and  expenses  incurred  in
connection  with  litigation  in which  they may be  involved  because  of their
offices with the  Portfolio,  unless,  as to  liability to the  Portfolio or its
investors,  it is finally adjudicated that they engaged in willful  misfeasance,
bad faith,  gross  negligence  or reckless  disregard of the duties  involved in
their  offices,  or  unless  with  respect  to any other  matter  it is  finally
adjudicated  that they did not act in good faith in the  reasonable  belief that
their  actions  were in the  best  interests  of the  Portfolio.  In the case of
settlement,  such  indemnification  will  not be  provided  unless  it has  been
determined   by  a  court  or  other  body   approving  the   settlement,   such
indemnification will not be provided unless it has been determined by a court or
other body  approving the  settlement or other  disposition,  or by a reasonable
determination,  based upon a review of  readily  available  facts,  by vote of a
majority  of  noninterested  Trustees  or in a written  opinion  of  independent
counsel, that such officers or Trustees have not engaged in willful misfeasance,
bad faith, gross negligence or reckless disregard of their duties.

   
Item 15.  Control Persons and Principle Holders of Securities
    
   
         As of November 29, 1996, EV Traditional Worldwide Health Sciences Fund,
Inc. (the  "Traditional  Fund") and EV Marathon  Worldwide Health Sciences Fund,
Inc. (the "Marathon Fund") owned approximately 88.0% and 11.8%, respectively, of
the value of the outstanding interests in the Portfolio. Because the Traditional
Fund controls the Portfolio,  the Traditional  Fund may take actions without the
approval of any other investor.  Each of the  Traditional  Fund and the Marathon
Fund has informed the Portfolio that whenever it is requested to vote on matters
pertaining to the fundamental policies of the Portfolio,  it will hold a meeting
of shareholders and will cast its vote as instructed by its interestholders.  It
is anticipated  that any other investor in the Portfolio  which is an investment
company  registered  under  the  1940 Act  would  follow  the same or a  similar
practice.  The Traditional  Fund is an open-end  management  investment  company
organized as a  corporation  under the laws of Maryland.  The Marathon Fund is a
series of Eaton Vance Growth Trust, an open-end  management  investment  company
organized  as  a  business  trust  under  the  laws  of  the   Commonwealth   of
Massachusetts.
    
Item 16.  Investment Advisory and Other Services
   
     The Adviser.  The Portfolio engages Mehta and Isaly Asset Management,  Inc.
("M&I" or the  "Adviser") as its  investment  adviser  pursuant to an investment
advisory  agreement dated June 24, 1996. As investment adviser to the Portfolio,
the Adviser manages the Portfolio's  investments,  subject to the supervision of
the Board of Trustees of the  Portfolio.  The  Adviser is also  responsible  for
effecting all security  transactions  on behalf of the Portfolio,  including the
allocation of principal transactions and portfolio brokerage and the negotiation
of commissions. See "Brokerage Allocation and Other Practices."
    
   
       For a description of the compensation that the Portfolio pays M&I under
the investment advisory agreement,  see "Management of the Portfolio" in Part A.
The advisory fee rate on average  daily net assets is reduced to 0.70% on assets
of $500  million but less than $1 billion,  to 0.65% on assets of $1 billion but
less than $1.5  billion,  to 0.60% on  assets of $1.5  billion  but less than $2
billion, to 0.55% on assets of $2 billion but less than $3 billion, and 0.50% on
assets of $3 billion and over.
    

         The performance fee adjustment to the advisory fee is as follows: after
12 months,  the basic  advisory fee is subject to upward or downward  adjustment
depending  upon  whether and to what extent the  investment  performance  of the
Portfolio  differs  by at least  one  percentage  point  from the  record of the
Standard  & Poor's  Index of 500  Common  Stocks  over  the  same  period.  Each
percentage  point  difference is multiplied by a performance  adjustment rate of
0.025%. The maximum  adjustment  plus/minus is 0.25%. One twelfth (1/12) of this
adjustment  is  applied  each  month to the  average  daily  net  assets  of the
Portfolio over the entire performance  period. This adjustment shall be based on
a rolling  period of up to and  including  the most recent 36 months.  Portfolio
performance shall be total return as computed under Rule 482 under the 1933 Act.

         The Portfolio's  investment advisory agreement with the Adviser remains
in effect until February 28, 1997; it may be continued  indefinitely  thereafter
so long as such  continuance  is approved at least annually (i) by the vote of a
majority of the Trustees of the Portfolio who are not interested  persons of the
Adviser or the Portfolio cast in person at a meeting specifically called for the
purpose  of voting on such  approval  and (ii) by the Board of  Trustees  of the
Portfolio or by vote of a majority of the outstanding  voting  securities of the
Portfolio.  The agreement may be terminated at any time without penalty on sixty
days'  written  notice by the Board of Trustees of the Portfolio or the Board of
Directors  of the  Adviser or by vote of a majority  of the  outstanding  voting
securities of the Portfolio.  The agreement will terminate  automatically in the
event of its  assignment.  The  agreement  provides  that the Adviser may render
services to others.  The agreement also provides that, in the absence of willful
misfeasance, bad faith, gross negligence or reckless disregard of obligations or
duties under the agreement on the part of the Adviser,  the Adviser shall not be
liable to the Portfolio or to any  interestholder for any act or omission in the
course of or connected  with rendering  services or for any losses  sustained in
the purchase, holding or sale of any security.

                  The Administrator. See "Management of the Portfolio" in Part A
for a description of the services Eaton Vance performs as  administrator  of the
Portfolio.  Under Eaton Vance's  administration  agreement  with the  Portfolio,
Eaton Vance receives a monthly  administration fee from the Portfolio.  This fee
is computed by applying the annual asset rate  applicable to that portion of the
average daily net assets of the Portfolio  throughout the month in each Category
as indicated below:
                                                            Annual
Category Average Daily Net Assets                           Asset Rate
- -----------       --------------------------------          -------------

1                 less than $500 million                     0.25%
2                 $500 million but less than $1 billion      0.23333
3                 $1 billion but less than $1.5 billion      0.21667
4                 $1.5 billion but less than $2 billion      0.20
5                 $2 billion but less than $3 billion        0.18333
6                 $3 billion and over                        0.16667
   
         Eaton Vance's  administration  agreement with the Portfolio will remain
in effect until February 28, 1997. The administration agreement may be continued
from  year to year  after  such  date so long as such  continuance  is  approved
annually  by the  vote of a  majority  of the  Trustees  of the  Portfolio.  The
administration  agreement may be terminated at any time without penalty on sixty
days' written notice by the Board of Trustees of either party  thereto,  or by a
vote of a majority of the outstanding  voting  securities of the Portfolio.  The
administration  agreement  will  terminate  automatically  in the  event  of its
assignment.  The administration agreement provides that, in the absence of Eaton
Vance's willful  misfeasance,  bad faith, gross negligence or reckless disregard
of its obligations or duties to the Portfolio under such agreement,  Eaton Vance
will  not be  liable  to the  Portfolio  or to any  interestholder  for any loss
incurred.  The agreement was initially  approved by the Trustees,  including the
non-interested Trustees, of the Portfolio at a meeting held on June 24, 1996.
    
         To the extent  necessary to comply with U.S. tax laws,  Eaton Vance has
employed IBT Trust Company  (Cayman) Ltd. to serve as the  sub-administrator  of
the Portfolio. The sub-administrator  maintains the Portfolio's principal office
and certain of its records and provides administrative  assistance in connection
with meetings of the Portfolio's Trustees and interestholders.
   
         Eaton Vance and EV are both wholly-owned  subsidiaries of EVC. BMR is a
wholly-owned   subsidiary  of  Eaton  Vance.   Eaton  Vance  and  BMR  are  both
Massachusetts business trusts, and EV is the trustee of Eaton Vance and BMR. The
Directors  of EV are Landon T. Clay,  M.  Dozier  Gardner,  James B.  Hawkes and
Benjamin A.  Rowland,  Jr. The  Directors of EVC consist of the same persons and
John G.L. Cabot and Ralph Z. Sorenson. Mr. Clay is chairman, Mr. Gardner is Vice
Chairman and Mr. Hawkes is president and chief  executive  officer of EVC, Eaton
Vance,  BMR and EV. All of the issued and outstanding  shares of Eaton Vance and
of EV are owned by EVC.  All of the  issued  and  outstanding  shares of BMR are
owned by Eaton Vance.  All shares of the outstanding  Voting Common Stock of EVC
are  deposited in a Voting  Trust which  expires  December 31, 1997,  the Voting
Trustees of which are Messrs.  Clay,  Gardner,  Hawkes and Rowland and Thomas E.
Faust, Jr. The Voting Trustees have unrestricted  voting rights for the election
of Directors of EVC. All of the  outstanding  voting trust receipts issued under
said  Voting  Trust are owned by certain of the  officers of Eaton Vance and BMR
who are also  officers or officers and Directors of EVC and EV. As of January 1,
1997, Messrs.  Clay,  Gardner and Hawkes each owned 24% and Messrs.  Rowland and
Faust owned 15% and 13%,  respectively,  of such voting trust receipts. Mr. Otis
is an  officer or Trustee  of the  Portfolio  and is a member of the EVC,  Eaton
Vance, BMR and EV organizations.  Messrs. Murphy,  O'Connor and Woodbury and Ms.
Sanders are officers of the  Portfolio  and are also members of the Eaton Vance,
BMR and/or EV  organizations.  Eaton Vance will  receive the fees paid under the
administration agreement.
    
         EVC  owns all of the  stock of  Energex  Energy  Corporation,  which is
engaged in oil and gas exploration  and  development.  In addition,  Eaton Vance
owns all of the stock of Northeast  Properties,  Inc.,  which is engaged in real
estate  investment.  EVC also  owns 24% of the  Class A shares  of Lloyd  George
Management (B.V.I.) Limited, a registered  investment  adviser.  EVC owns all of
the stock of Fulcrum  Management,  Inc.  and MinVen  Inc.,  which are engaged in
precious metal mining venture  investment and management.  EVC, BMR, Eaton Vance
and EV may also enter into other businesses.

         Custodian.  Investors  Bank & Trust Company  ("IBT"),  89 South Street,
Boston, Massachusetts,  acts as custodian for the Portfolio. IBT has the custody
of all  securities  of the  Portfolio  purchased in the United  States,  and its
subsidiary, IBT Fund Services (Canada) Inc., 1 First Canadian Place, King Street
West,  Toronto,  Ontario,  Canada,  maintains the Portfolio's general ledger and
computes  the  daily net  asset  value of  interests  in the  Portfolio.  In its
capacity  as  custodian,  IBT  attends to details in  connection  with the sale,
exchange,  substitution,  or transfer of or other dealings with the  Portfolio's
investments,  receives  and  disburses  all funds,  and performs  various  other
ministerial duties upon receipt of proper instructions from the Portfolio.

         Portfolio  securities,  if any,  purchased by the Portfolio in the U.S.
are maintained in the custody of IBT or of other domestic banks or depositories.
Portfolio securities purchased outside of the U.S. are maintained in the custody
of foreign banks and trust  companies  that are members of IBT's Global  Custody
Network, or foreign depositories used by such foreign banks and trust companies.
Each of the  domestic  and  foreign  custodial  institutions  holding  portfolio
securities  has been  approved  by the Board of  Trustees  of the  Portfolio  in
accordance with regulations under the 1940 Act.

         IBT charges fees which are competitive within the industry.  These fees
for the Portfolio  relate to (1) custody services based upon a percentage of the
market values of Portfolio  securities;  (2) bookkeeping and valuation  services
provided at an annual rate;  (3) activity  charges,  primarily the result of the
number  of  portfolio  transactions;  and  (4)  reimbursement  of  out-of-pocket
expenses.  These  fees are then  reduced by a credit  for cash  balances  of the
Portfolio at the custodian equal to 75% of the 91-day U.S. Treasury Bill auction
rate applied to the  Portfolio's  average daily  collected  balances.  Landon T.
Clay, a Director of EVC and an officer, Trustee or Director of other entities in
the Eaton Vance  organization,  owns  approximately  13% of the voting  stock of
Investors   Financial  Services  Corp.,  the  holding  company  parent  of  IBT.
Management  believes that such  ownership  does not create an affiliated  person
relationship between the Portfolio and IBT under the 1940 Act.
   
         IBT also  provides  services  in  connection  with the  preparation  of
interestholder reports and electronic filing of such reports with the Commission
for which it receives a separate fee.
    

         Independent  Accountants.  Coopers  &  Lybrand  Chartered  Accountants,
Toronto,  Ontario,  Canada,  are the  independent  accountants of the Portfolio,
providing  audit   services,   tax  return   preparation,   and  assistance  and
consultation with respect to the preparation of filings with the Commission.

Item 17.  Brokerage Allocation and Other Practices

         Decisions  concerning the execution of portfolio security  transactions
by the  Portfolio,  including the selection of the market and the  broker-dealer
firm, are made by the Adviser.

         The Adviser places the portfolio security transactions of the Portfolio
and of certain other  accounts  managed by the Adviser for  execution  with many
broker-dealer  firms.  The Adviser uses its best efforts to obtain  execution of
portfolio  transactions  at prices that are  advantageous  to the  Portfolio and
(when a  disclosed  commission  is  being  charged)  at  reasonably  competitive
commission  rates.  In seeking  such  execution,  the Adviser  will use its best
judgment in evaluating the terms of a transaction,  and will give  consideration
to various relevant factors,  including without  limitation the size and type of
the  transaction,  the general  execution and  operational  capabilities  of the
broker-dealer,  the nature and  character  of the market for the  security,  the
confidentiality,  speed and  certainty of effective  execution  required for the
transaction, the reputation,  reliability, experience and financial condition of
the   broker-dealer,   the  value  and  quality  of  services  rendered  by  the
broker-dealer  in this and other  transactions,  and the  reasonableness  of the
commission,   if  any.   Transactions   on  stock  exchanges  and  other  agency
transactions  involve  the  payment by the  Portfolio  of  negotiated  brokerage
commissions.  Such commissions vary among different  broker-dealer  firms, and a
particular  broker-dealer  may charge  different  commissions  according to such
factors as the difficulty and size of the transaction and the volume of business
done with such broker-dealer. Transactions in foreign securities usually involve
the payment of fixed  brokerage  commissions,  which are  generally  higher than
those in the United States.  There is generally no stated commission in the case
of  securities  traded in the  over-the-counter  markets,  but the price paid or
received by the  Portfolio  usually  includes an  undisclosed  dealer  markup or
markdown. In an underwritten offering the price paid by the Portfolio includes a
disclosed  fixed  commission or discount  retained by the underwriter or dealer.
Although commissions paid on portfolio transactions will, in the judgment of the
Adviser,  be  reasonable  in  relation  to the value of the  services  provided,
commissions  exceeding  those  which  another  firm might  charge may be paid to
broker-dealers  who were  selected  to  execute  transactions  on  behalf of the
Portfolio  and the Adviser's  other clients in part for providing  brokerage and
research services to the Adviser.
   
         As  authorized in Section 28(e) of the 1934 Act, a broker or dealer who
executes  a  portfolio  transaction  on behalf of the  portfolio  may  receive a
commission  which is in excess of the  amount of  commission  another  broker or
dealer  would  have  charged  for  effecting  that  transaction  if the  Adviser
determine in good faith that such  commission  was reasonable in relation to the
value of the brokerage and research services provided. This determination may be
made on the basis of either that  particular  transaction or on the basis of the
overall  responsibilities which the Adviser and its affiliates have for accounts
over   which  they   exercise   investment   discretion.   In  making  any  such
determination,  the Adviser will not attempt to place a specific dollar value on
the brokerage and research services provided or to determine what portion of the
commission  should be related to such services.  Brokerage and research services
may include advice as to the value of securities,  the advisability of investing
in,  purchasing,  or selling  securities,  and the availability of securities or
purchasers or sellers of securities;  furnishing analyses and reports concerning
issuers, industries, securities, economic factors and trends, portfolio strategy
and the  performance  of accounts;  and effecting  securities  transactions  and
performing functions incidental thereto (such as clearance and settlement);  and
the "Research Services" referred to in the next paragraph.
    
         It is a common  practice in the  investment  advisory  industry for the
advisers of investment  companies,  institutions  and other investors to receive
research,  statistical  and  quotation  services,  data,  information  and other
services,  products and materials  which assist such advisers in the performance
of their investment  responsibilities  ("Research Services") from broker-dealers
which execute  portfolio  transactions for the clients of such advisers and from
third parties with which such broker-dealers have arrangements.  Consistent with
this  practice,  the Adviser may receive  Research  Services from  broker-dealer
firms with which the Adviser places the portfolio  transactions of the Portfolio
and from third parties with which these broker-dealers have arrangements.  These
Research  Services  may  include  such  matters as general  economic  and market
reviews,  industry and company reviews,  evaluations of securities and portfolio
strategies  and  transactions,  recommendations  as to the  purchase and sale of
securities  and other  portfolio  transactions,  financial,  industry  and trade
publications, news and information services, pricing and quotation equipment and
services,  and research oriented  computer  hardware,  software,  data bases and
services.  Any particular  Research Service obtained through a broker-dealer may
be used by the  Adviser in  connection  with  client  accounts  other than those
accounts which pay commissions to such broker-dealer.  Any such Research Service
may be  broadly  useful  and of value to the  Adviser  in  rendering  investment
advisory  services to all or a  significant  portion of its  clients,  or may be
relevant and useful for the management of only one client's  account or of a few
clients'  accounts,  or may be useful for the  management of merely a segment of
certain  clients'  accounts,  regardless of whether any such account or accounts
paid  commissions to the  broker-dealer  through which such Research Service was
obtained.  The  advisory fee paid by the  Portfolio  is not reduced  because the
Adviser receives such Research  Services.  The Adviser  evaluates the nature and
quality of the various Research  Services obtained through  broker-dealer  firms
and  attempts to  allocate  sufficient  commissions  to such firms to ensure the
continued  receipt of Research Services which the Adviser believes are useful or
of value to it in rendering investment advisory services to its clients.
   
         Subject to the requirement  that the Adviser shall use its best efforts
to  seek  to  execute  portfolio  security  transactions  of  the  Portfolio  at
advantageous prices and at reasonably  competitive  commission rates or spreads,
the  Adviser is  authorized  to  consider  as a factor in the  selection  of any
broker-dealer  firm with whom Portfolio  orders may be placed the fact that such
firm has sold or is selling  shares of investment  companies  sponsored by Eaton
Vance. This policy is not inconsistent  with a rule of the National  Association
of Securities Dealers, Inc. ("NASD"),  which rule provides that no firm which is
a member of the NASD shall favor or disfavor the  distribution  of shares of any
particular  investment company or group of investment  companies on the basis of
brokerage commissions received or expected by such firm from any source.
    
         Securities  considered  as  investments  for the  Portfolio may also be
appropriate  for  other  investment  accounts  managed  by  the  Adviser  or its
affiliates.   The  Adviser   will  attempt  to  allocate   equitably   portfolio
transactions  among the  Portfolio and the  portfolios  of its other  investment
accounts  whenever  decisions  are made to  purchase or sell  securities  by the
Portfolio and one or more of such other accounts simultaneously.  In making such
allocations,  the main factors to be considered  are the  respective  investment
objectives  of the  Portfolio  and such other  accounts,  the  relative  size of
portfolio  holdings of the same or comparable  securities,  the  availability of
cash for investment by the Portfolio and such  accounts,  the size of investment
commitments  generally  held by the Portfolio and such accounts and the opinions
of the persons  responsible  for  recommending  investments to the Portfolio and
such accounts. While this procedure could have a detrimental effect on the price
or amount of the securities  available to the Portfolio from time to time, it is
the opinion of the Trustees of the Portfolio  that the benefits  available  from
the  Adviser's  organization  outweigh  any  disadvantage  that may  arise  from
exposure to simultaneous transactions.

Item 18.  Capital Stock and Other Securities

         Under the Portfolio's Declaration of Trust, the Trustees are authorized
to issue  interests in the Portfolio.  Investors are entitled to participate pro
rata in distributions of taxable income, loss, gain and credit of the Portfolio.
Upon  dissolution of the Portfolio,  the Trustees shall  liquidate the assets of
the  Portfolio and apply and  distribute  the proceeds  thereof as follows:  (a)
first,  to the payment of all debts and  obligations  of the  Portfolio to third
parties  including,  without  limitation,  the retirement of  outstanding  debt,
including  any debt  owned to holders of record of  interests  in the  Portfolio
("Holders") or their  affiliates,  and the expenses of  liquidation,  and to the
setting up of any reserves for  contingencies  which may be  necessary;  and (b)
second,  in accordance with the Holders'  positive Book Capital Account balances
after adjusting Book Capital  Accounts for certain  allocations  provided in the
Declaration  of Trust  and in  accordance  with the  requirements  described  in
Treasury  Regulations  Section   1.704-1(b)(2)(ii)(b)(2).   Notwithstanding  the
foregoing, if the Trustees shall determine that an immediate sale of part or all
of the  assets of the  Portfolio  would  cause  undue loss to the  Holders,  the
Trustees,  in order to avoid such loss, may, after having given  notification to
all  the  Holders,  to  the  extent  not  then  prohibited  by  the  law  of any
jurisdiction  in which the Portfolio is then formed or qualified and  applicable
in the circumstances, either defer liquidation of and withhold from distribution
for a reasonable  time any assets of the  Portfolio  except  those  necessary to
satisfy the  Portfolio's  debts and  obligations or distribute  the  Portfolio's
assets  to the  Holders  in  liquidation.  Interests  in the  Portfolio  have no
preference,  preemptive,  conversion  or  similar  rights and are fully paid and
nonassessable,  except as set forth below. Interests in the Portfolio may not be
transferred.  Certificates  representing an investor's interest in the Portfolio
are issued only upon the written request of a Holder.

         Each  Holder is  entitled  to vote in  proportion  to the amount of its
interest in the Portfolio.  Holders do not have  cumulative  voting rights.  The
Portfolio is not required and has no current  intention to hold annual  meetings
of Holders but the Portfolio  will hold meetings of Holders when in the judgment
of the Portfolio's  Trustees it is necessary or desirable to submit matters to a
vote of Holders at a meeting.  Any action  which may be taken by Holders  may be
taken  without a  meeting  if  Holders  holding  more than 50% of all  interests
entitled to vote (or such larger proportion  thereof as shall be required by any
express  provision of the Declaration of Trust of the Portfolio)  consent to the
action in writing  and the  consents  are filed with the  records of meetings of
Holders.

         The Portfolio's  Declaration of Trust may be amended by vote of Holders
of more than 50% of all  interests in the Portfolio at any meeting of Holders or
by an  instrument  in writing  without a meeting,  executed by a majority of the
Trustees and consented to by the Holders of more than 50% of all interests.  The
Trustees may also amend the Declaration of Trust (without the vote or consent of
Holders) to change the Portfolio's name or the state or other jurisdiction whose
law shall be the  governing  law, to supply any omission or to cure,  correct or
supplement any ambiguous,  defective or inconsistent  provision,  to conform the
Declaration  of  Trust  to  applicable  federal  law  or  regulations  or to the
requirements  of the Code,  or to  change,  modify  or  rescind  any  provision,
provided  that such change,  modification  or  rescission  is  determined by the
Trustees to be necessary  or  appropriate  and not to have a materially  adverse
effect  on  the  financial  interests  of  the  Holders.  No  amendment  of  the
Declaration  of Trust which would change any rights with respect to any Holder's
interest  in  the  Portfolio  by  reducing  the  amount  payable   thereon  upon
liquidation of the Portfolio may be made, except with the vote or consent of the
Holders of two-thirds of all interests.  References in the  Declaration of Trust
and in Part A or this  Part B to a  specified  percentage  of, or  fraction  of,
interests in the Portfolio,  means Holders whose  combined Book Capital  Account
balances  represent such  specified  percentage or fraction of the combined Book
Capital Account balance of all, or a specified group of, Holders.

         The  Portfolio  may merge or  consolidate  with any other  corporation,
association,  trust  or  other  organization  or may  sell  or  exchange  all or
substantially  all of its  assets  upon such terms and  conditions  and for such
consideration  when and as  authorized  by the Holders of (a) 67% or more of the
interests in the Portfolio present or represented at the meeting of Holders,  if
Holders of more than 50% of all interests are present or  represented  by proxy,
or (b) more than 50% of all  interests,  whichever is less. The Portfolio may be
terminated (i) by the affirmative vote of Holders of not less than two-thirds of
all interests at any meeting of Holders or by an instrument in writing without a
meeting,  executed by a majority of the Trustees and  consented to by Holders of
not less than  two-thirds of all  interests,  or (ii) by the Trustees by written
notice to the Holders.

         In accordance with the Declaration of Trust,  there normally will be no
meetings of the investors for the purpose of electing  Trustees unless and until
such time as less than a  majority  of the  Trustees  holding  office  have been
elected by investors.  In such an event,  the Trustees of the Portfolio  then in
office will call an investors' meeting for the election of Trustees.  Except for
the foregoing  circumstances,  and unless  removed by action of the investors in
accordance  with the  Portfolio's  Declaration  of  Trust,  the  Trustees  shall
continue to hold office and may appoint successor Trustees.

         The  Declaration  of Trust  provides  that no person  shall  serve as a
Trustee if  investors  holding  two-thirds  of the  outstanding  interests  have
removed  him from that  office  either by a written  declaration  filed with the
Portfolio's custodian or by votes cast at a meeting called for that purpose. The
Declaration  of Trust further  provides that under  certain  circumstances,  the
investors  may call a  meeting  to remove a Trustee  and that the  Portfolio  is
required to provide  assistance in  communicating  with  investors  about such a
meeting.

         The  Portfolio  is  organized as a trust under the laws of the State of
New York.  Investors in the  Portfolio  will be held  personally  liable for its
obligations  and  liabilities,  subject,  however,  to  indemnification  by  the
Portfolio in the event that there is imposed upon an investor a greater  portion
of the  liabilities  and  obligations  of the Portfolio  than its  proportionate
interest in the Portfolio. The Portfolio intends to maintain fidelity and errors
and omissions insurance deemed adequate by the Trustees.  Therefore, the risk of
an investor incurring financial loss on account of investor liability is limited
to  circumstances  in which both inadequate  insurance  exists and the Portfolio
itself is unable to meet its obligations.

         The  Declaration  of Trust  further  provides that  obligations  of the
Portfolio  are not  binding  upon the  Trustees  individually  but only upon the
property  of the  Portfolio  and that the  Trustees  will not be liable  for any
action or failure to act,  but nothing in the  Declaration  of Trust  protects a
Trustee  against any liability to which he would  otherwise be subject by reason
of willful  misfeasance,  bad faith, gross negligence,  or reckless disregard of
the duties involved in the conduct of his office.

Item 19.  Purchase, Redemption and Pricing of Securities

         Interests  in the  Portfolio  are issued  solely in  private  placement
transactions  that do not involve any  "public  offering"  within the meaning of
Section 4(2) of the  Securities  Act of 1933.  See "Purchase of Interests in the
Portfolio" and  "Redemption or Decrease of Interest" in Part A. See Part A, Item
7 regarding the pricing of interests in the Portfolio.

         To the extent sales prices are available, securities that are traded on
a recognized  stock  exchange,  whether U.S. or foreign,  are valued at the last
sale price on that exchange prior to the time when assets are valued or prior to
the close of trading on the New York Stock Exchange. In the event that there are
no sales, the last available sale price will be used. If a security is traded on
more than one  exchange,  the latest  price on the  exchange  where the stock is
primarily  traded will be used.  If there is no sale that day or if the security
is  not  listed,  the  security  is  valued  at its  last  sale  quotation.  The
calculation   of  the   Portfolio's   net  asset   value  may  not  take   place
contemporaneously  with the times  noted  above for  determining  the  prices of
certain portfolio securities, including foreign securities. If events materially
effecting the value of such securities  occur between the time when their prices
are determined and the time the Portfolio's net asset value is calculated,  such
securities  will be  valued at fair  value as  determined  in good  faith by the
Trustees of the Portfolio.  Also, for any security for which  application of the
preceding  methods of valuation results in a price for a security that is deemed
not to be representative of the market value of such security, the security will
be valued at fair value under the supervision and responsibility of the Board of
Trustees.

         Futures contracts and call options written on portfolio securities will
be priced at the latest  sales  price on the  principal  exchange  on which such
options are normally  traded or, if there have been no sales on such exchange on
that day, at the closing asked price.  Short-term  investments having a maturity
of 60 days or less are valued on the basis of amortized  cost.  All other assets
and  securities  held by the Portfolio  (including  restricted  securities)  are
valued at fair value as  determined  in good  faith  under the  supervision  and
responsibility  of the Board of Trustees.  Any assets that are  denominated in a
foreign  currency are translated in U.S. dollars of the last quoted spot rate of
exchange prevailing on each valuation date.

Item 20.  Tax Status

         The  Portfolio  has been  advised by tax  counsel  that,  provided  the
Portfolio  is operated at all times  during its  existence  in  accordance  with
certain  organizational  and  operational  documents,  the  Portfolio  should be
classified  as a  partnership  under the Code and it should  not be a  "publicly
traded   partnership"   within  the  meaning  of  Section   7704  of  the  Code.
Consequently,  the Portfolio does not expect that it will be required to pay any
federal income tax.
   
         Under  Subchapter  K of the Code, a  partnership  is  considered  to be
either an  aggregate  of its  members or a separate  entity  depending  upon the
factual and legal  context in which the  question  arises.  Under the  aggregate
approach,  each  partner  is  treated as an owner of an  undivided  interest  in
partnership assets and operations. Under the entity approach, the partnership is
treated  as a  separate  entity in which  partners  have no direct  interest  in
partnership assets and operations. The Portfolio has been advised by tax counsel
that,  in the case of a Holder that seeks to qualify as a  regulated  investment
company (a "RIC"),  the aggregate  approach  should apply,  and each such Holder
should accordingly be deemed to own a proportionate  share of each of the assets
of the  Portfolio  and to be  entitled  to the  gross  income  of the  Portfolio
attributable  to that share for purposes of all  requirements of Sections 851(b)
and  852(b)(5)  of the Code.  Further,  the  Portfolio  has been  advised by tax
counsel that each Holder that seeks to qualify as a regulated investment company
(a "RIC"),  should be deemed to hold its proportionate  share of the Portfolio's
assets for the period  the  Portfolio  has held the assets or for the period the
Holder has been an investor in the  Portfolio,  whichever is shorter.  Investors
should consult their tax advisers  regarding whether the entity or the aggregate
approach  applies  to  their  investment  in the  Portfolio  in  light  of their
particular tax status and any special tax rules applicable to them.
    
         In order to enable a Holder that is otherwise  eligible to qualify as a
RIC, the Portfolio  intends to satisfy the  requirements  of Subchapter M of the
Code relating to sources of income and diversification of assets as if they were
applicable to the Portfolio and to allocate and permit  withdrawals  in a manner
that will enable a Holder which is a RIC to comply with those requirements.  The
Portfolio will allocate at least annually to each Holder it's distributive share
of the Portfolio's net investment  income,  net realized  capital gains, and any
other items of income,  gain, loss,  deduction or credit in a manner intended to
comply  with the Code and  applicable  Treasury  regulations.  Tax  counsel  has
advised the Portfolio  that the  Portfolio's  allocations  of taxable income and
loss should have "economic effect" under applicable Treasury regulations.

         To the extent the cash proceeds of any  withdrawal  (or,  under certain
circumstances,  such  proceeds  plus  the  value  of any  marketable  securities
distributed to an investor) ("liquid proceeds") exceed a Holder's adjusted basis
of his interest in the Portfolio,  the Holder will generally  realize a gain for
federal income tax purposes.  If, upon a complete withdrawal  (redemption of the
entire interest), the Holder's adjusted basis of his interest exceeds the liquid
proceeds  of such  withdrawal,  the  Holder  will  generally  realize a loss for
federal income tax purposes.  The tax  consequences  of a withdrawal of property
(instead of or in addition to liquid proceeds) will be different and will depend
on the specific factual circumstances.  A Holder's adjusted basis of an interest
in the Portfolio will generally be the aggregate prices paid therefor (including
the  adjusted  basis of  contributed  property and any gain  recognized  on such
contribution),  increased by the amounts of the Holder's  distributive  share of
items of income  (including  interest income exempt from federal income tax) and
realized net gain of the Portfolio,  and reduced, but not below zero, by (i) the
amounts of the Holder's  distributive share of items of Portfolio loss, and (ii)
the amount of any cash distributions (including distributions of interest income
exempt from federal income tax and cash  distributions  on withdrawals  from the
Portfolio)  and the basis to the Holder of any property  received by such Holder
other than in  liquidation,  and (iii) the  Holder's  distributive  share of the
Portfolio's  nondeductible  expenditures  not  properly  chargeable  to  capital
account.  Increases  or  decreases  in  a  Holder's  share  of  the  Portfolio's
liabilities  may also result in  corresponding  increases  or  decreases in such
adjusted  basis.  Distributions  of liquid  proceeds  in  excess  of a  Holder's
adjusted  basis in its  interest  in the  Portfolio  immediately  prior  thereto
generally will result in the  recognition of gain to the Holder in the amount of
such excess.

         Foreign  exchange  gains  and  losses  realized  by the  Portfolio  and
allocated to the RIC in connection with the  Portfolio's  investments in foreign
securities and certain options, futures or forward contracts or foreign currency
may be treated as ordinary  income and losses under  special tax rules.  Certain
options,  futures or forward  contracts of the  Portfolio  may be required to be
marked  to  market  (i.e.,  treated  as if  closed  out) on the last day of each
taxable year, and any gain or loss realized with respect to these  contracts may
be  required to be treated as 60%  long-term  and 40%  short-term  gain or loss.
Positions of the  Portfolio in securities  and  offsetting  options,  futures or
forward  contracts may be treated as "straddles" and be subject to other special
rules that may, upon allocation of the Portfolio's  income,  gain or loss to the
RIC,  affect the amount,  timing and  character  of the RIC's  distributions  to
shareholders.  Certain uses of foreign currency and foreign currency derivatives
such as options,  futures,  forward  contracts  and swaps and  investment by the
Portfolio in the stock of certain "passive foreign investment  companies" may be
limited  or a tax  election  may be made,  if  available,  in order to enable an
investor  that  is a  RIC  to  preserve  its  qualification  as a RIC  or  avoid
imposition of a tax on such an investor.

         The Portfolio  anticipates  that it will be subject to foreign taxes on
its income (including,  in some cases,  capital gains) from foreign  securities.
Tax conventions  between certain  countries and the U.S. may reduce or eliminate
such taxes.

         An entity that is treated as a partnership  under the Code, such as the
Portfolio, is generally treated as a partnership under state and local tax laws,
but certain states may have difference  entity  classification  criteria and may
therefore  reach  a  different  conclusion.  Entities  that  are  classified  as
partnerships  are not treated as separate  taxable entities under most state and
local tax laws,  and the income of a  partnership  is considered to be income of
partners both in timing and in character.  The exemption of interest  income for
federal income tax purposes does not  necessarily  result in exemption under the
income  or tax  laws of any  state or local  taxing  authority.  The laws of the
various states and local taxing authorities vary with respect to the taxation of
such interest income,  as well as to the status of a partnership  interest under
state and local tax laws,  and each Holder of an interest  in the  Portfolio  is
advised to consult his own tax adviser.

         The  foregoing  discussion  does not  address  the  special  tax  rules
applicable  to  certain  classes  of  investors,  such as  tax-exempt  entities,
insurance companies and financial  institutions.  Investors should consult their
own tax  advisers  with  respect  to  special  tax rules that may apply in their
particular  situations,  as well as the state, local or foreign tax consequences
of investing in the Portfolio.

Item 21.  Underwriters
   
         The  placement  agent for the  Portfolio  is Eaton Vance  Distributors,
Inc.,  which is a  wholly-owned  subsidiary of Eaton Vance and which receives no
compensation  from  the  Portfolio  for  serving  in this  capacity.  Investment
companies,  common and commingled  trust funds,  and similar  organizations  and
entities may continuously invest in the Portfolio.
    
Item 22.  Calculation of Performance Data

         Not applicable.

Item 23.  Financial Statements

         The following  financial  statements included herein have been included
in  reliance  upon the report of  Coopers & Lybrand  Chartered  Accountants,  as
experts in accounting and auditing.
   
         Statement of Assets and Liabilities as of August 31, 1996
         Report of Independent Accountants

    
<PAGE>


                              Financial Statements
   
                       WORLDWIDE HEALTH SCIENCES PORTFOLIO
                       STATEMENT OF ASSETS AND LIABILITIES
                                 August 31, 1996

Assets:
        Cash..................................................         $100,020
        Deferred organization expenses........................           12,000
                                                                         ------
                  Total assets................................         $112,020

Liabilities:
        Accrued organization expenses.........................           12,000
                                                                         ------
Net assets....................................................         $100,020
                                                                       ========

NOTES:
   
(1) Worldwide Health Sciences Portfolio (the "Portfolio") was organized as a New
York Trust on March 26, 1996 and has been inactive  since that date,  except for
matters relating to its  organization and registration as an investment  company
under the  Investment  Company Act of 1940 and the sale of interests  therein at
the purchase  price of $100,000 to Boston  Management  & Research,  $10 to Eaton
Vance  Management  and $10 EV  Marathon  Worldwide  Health  Sciences  Fund  (the
"Initial Interests").
    
(2)  Organization  expenses  are  being  deferred  and  will be  amortized  on a
straight-line  basis over a period not to exceed five years,  commencing  on the
effective date of the Portfolio's initial offering of its interests.  The amount
paid by the Portfolio on any withdrawal by the holders of the Initial  Interests
of any of the respective  Initial  Interests will be reduced by a portion of any
unamortized organization expenses, determined by the proportion of the amount of
the Initial Interests withdrawn to the Initial Interests then outstanding.

(3) At 4:00 p.m., New York City time, on each business day of the Portfolio, the
value of an investor's  interest in the Portfolio is equal to the product of (i)
the aggregate net asset value of the Portfolio multiplied by (ii) the percentage
representing  that investor's  share of the aggregate  interest in the Portfolio
effective for that day.




<PAGE>


                        REPORT OF INDEPENDENT ACCOUNTANTS

   
To the Trustees and Investors of
      Worldwide Health Sciences Portfolio:

         We have audited the accompanying statement of assets and liabilities of
Worldwide  Health  Sciences  Portfolio (a New York Trust) as of August 31, 1996.
This financial  statement is the  responsibility of the Portfolio's  management.
Our responsibility is to express an opinion on this financial statement based on
our audit.

         We conducted our audit in accordance with generally  accepted  auditing
standards.  Those standards require that we plan and perform the audit to obtain
reasonable  assurance about whether the financial  statement is free of material
misstatement.  An audit includes examining, on a test basis, evidence supporting
the amounts and disclosures in the financial  statement.  An audit also includes
assessing the  accounting  principles  used and  significant  estimates  made by
management,  as well as evaluating the overall financial statement presentation.
We believe that our audit provides a reasonable basis for our opinion.

         In our opinion,  the  financial  statement  referred to above  presents
fairly,  in all material  respects,  the financial  position of Worldwide Health
Sciences  Portfolio as of August 31, 1996, in conformity with generally accepted
accounting principles.
    

                                    /s/ Coopers & Lybrand Chartered Accountants
   
Toronto, Ontario
September 2, 1996
    


<PAGE>










                                     PART C

Item 24.  Financial Statements and Exhibits

     (a) Financial  Statements The financial  statements called for by this Item
are included in Part B and listed in Item 23 hereof.

     (b)  Exhibits 
   
     1. (a)  Declaration  of Trust  dated  March 26,  1996  filed
electronically  as Exhibit No. 1(a) to the  Registrant's  original  Registration
Statement   filed  with  the   Commission  on  July  22,  1996   (Accession  No.
0001003291-96-000048)  and  incorporated  herein  by  reference  (the  "Original
Registration Statement").

         (b)  Amendment  to Declaration of Trust  dated  June  24,  1996  filed
electronically  as Exhibit No. 1(b) to the Original  Registration  Statement and
incorporated herein by reference.

     2. By-Laws of the Registrant adopted March 26, 1996 filed electronically as
Exhibit No. 2 to the Original Registration  Statement and incorporated herein by
reference.

     5. Investment  Advisory Agreement between the Registrant and M&I dated June
24,  1996 filed  electronically  as Exhibit No. 5 to the  Original  Registration
Statement and incorporated herein by reference.

     6.  Placement  Agent  Agreement with Eaton Vance  Distributors,  Inc. dated
November 1, 1996 filed herewith.
    
     7. The  Securities  and Exchange  Commission  has granted the Registrant an
exemptive order that permits the Registrant to enter into deferred  compensation
arrangements  with  its  independent  Trustees.  See In the  Matter  of  Capital
Exchange Fund, Inc., Release No. IC-20671 (November 1, 1994).
   
     8.  Custodian  Agreement with Investors Bank & Trust Company dated June 24,
1996  filed  electronically  as  Exhibit  No.  8 to  the  Original  Registration
Statement and incorporated herein by reference.

     9. (a)  Accounting  and  Interestholder  Services  Agreement  with IBT Fund
Services (Canada) Inc. dated June 25, 1996 filed herewith.

        (b) Administration Agreement between the Registrant and Eaton Vance
Management dated June 24, 1996 filed  electronically  as Exhibit No. 9(b) to the
Original Registration Statement and incorporated herein by reference.

        (c) Sub-Administration Agreement among  the  Registrant,   Eaton  Vance
Management  and IBT Trust  Company  (Cayman)  Ltd.  dated  June 24,  1996  filed
herewith.

     13.  Investment  representation  letter of Boston  Management  and Research
dated May 31,  1996  filed  electronically  as  Exhibit  No. 13 to the  Original
Registration Statement and incorporated herein by reference.
    
Item 25.  Persons Controlled by or under Common Control with Registrant

         Not applicable.

Item 26.  Number of Holders of Securities
   
                        (1)                                    (2)
                                                           Number of
                  Title of Class                     Record Holders as of
                  -----------------                   November 29, 1996
                                                       -----------------------

                  Interests                                   4
    
Item 27.  Indemnification
   
         Reference is hereby made to Article V of the  Registrant's  Declaration
of Trust,  filed  electronically  as Exhibit 1(a) to the  Original  Registration
Statement and incorporated herein by reference.
    
         The Trustees and officers of the  Registrant  and the  personnel of the
Registrant's  investment  adviser  are  insured  under an errors  and  omissions
liability  insurance  policy.  The  Registrant and its officers are also insured
under the fidelity bond required by Rule 17g-1 under the Investment  Company Act
of 1940.

Item 28.  Business and Other Connections

         To the knowledge of the Portfolio, none of the directors or officers of
the Portfolio's  investment  adviser,  except as set forth on their Forms ADV as
filed  with the  Securities  and  Exchange  Commission,  is engaged in any other
business,  profession,  vocation or employment of a substantial  nature,  except
that certain  directors  and officers may also hold various  positions  with and
engage in business for affiliates of the investment adviser.

Item 29.  Principal Underwriters

         Not applicable.

Item 30.  Location of Accounts and Records

         All applicable accounts,  books and documents required to be maintained
by the Registrant by Section 31(a) of the Investment Company Act of 1940 and the
Rules  promulgated   thereunder  are  in  the  possession  and  custody  of  the
Registrant's custodian, Investors Bank & Trust Company, 89 South Street, Boston,
MA 02111,  with the  exception  of certain  corporate  documents  and  portfolio
trading  documents,  which are in the possession and custody of the Registrant's
administrator  at  24  Federal  Street,  Boston,  MA  02110.  Certain  corporate
documents are also  maintained by IBT Trust Company  (Cayman)  Ltd., The Bank of
Nova Scotia Building,  P. O. Box 501, George Town, Grand Cayman, Cayman Islands,
British West  Indies,  and certain  investor  account and  Portfolio  accounting
records are held by IBT Fund Services  (Canada)  Inc., 1 First  Canadian  Place,
King Street West, Suite 2800, P.O. Box 231,  Toronto,  Ontario,  Canada M5X 1C8.
The  Registrant is informed that all  applicable  accounts,  books and documents
required to be maintained by registered  investment  advisers are in the custody
and possession of the Registrant's investment adviser.

Item 31.  Management Services

         Not applicable.

Item 32.  Undertakings

         Not applicable.


<PAGE>














                                   SIGNATURES


   
         Pursuant to the requirements of the Investment Company Act of 1940, the
Registrant has duly caused this Registration Statement on Form N-1A to be signed
on its behalf by the undersigned, thereunto duly authorized in Hamilton, Bermuda
on the 16th day of December, 1996.

                                            WORLDWIDE HEALTH SCIENCES PORTFOLIO


                                            By:      /s/ James B. Hawkes
                                                     James B. Hawkes, President


    
<PAGE>


                                INDEX TO EXHIBITS

   
Exhibit No.       Description of Exhibit
- -----------       -----------------------
6                  Placement Agent Agreement with Eaton Vance Distributors
                   dated November 1, 1996.

9                 (a) Accounting and Interestholder Services Agreement with IBT
                      Fund Services (Canada)Inc. dated June 24, 1996.

9                 (c) Sub-Administration Agreement among the Registrant, Eaton
                      Vance Management and IBT Trust Company (Cayman) Ltd.
                      dated June 24, 1996.

    









                            PLACEMENT AGENT AGREEMENT



                                November 1, 1996


Eaton Vance Distributors, Inc.
24 Federal Street
Boston, Massachusetts  02110

Gentlemen:

         This is to confirm that, in consideration of the agreements hereinafter
contained,  the undersigned,  Worldwide Health Sciences Portfolio (the "Trust"),
an open-end  diversified  management  investment  company  registered  under the
Investment Company Act of 1940, as amended (the "1940 Act"),  organized as a New
York trust, has agreed that Eaton Vance  Distributors,  Inc.  ("EVD"),  formerly
named EV  Distributors,  Inc.,  shall be the  placement  agent  (the  "Placement
Agent") of Interests in the Trust ("Trust Interests").

         1.  Services as Placement Agent.

         1.1 EVD will act as Placement Agent of the Trust  Interests  covered by
the Trust's registration  statement then in effect under the 1940 Act. In acting
as Placement  Agent under this Placement  Agent  Agreement,  neither EVD nor its
employees or any agents thereof shall make any offer or sale of Trust  Interests
in a manner which would require the Trust  Interests to be registered  under the
Securities Act of 1933, as amended (the "1933 Act").

         1.2 All  activities  by EVD and its agents and  employees  as Placement
Agent of Trust  Interests  shall  comply  with all  applicable  laws,  rules and
regulations,  including,  without limitation,  all rules and regulations adopted
pursuant  to the  1940  Act by  the  Securities  and  Exchange  Commission  (the
"Commission").

         1.3 Nothing  herein  shall be  construed to require the Trust to accept
any offer to  purchase  any Trust  Interests,  all of which  shall be subject to
approval by the Board of Trustees.

         1.4 The Portfolio shall furnish from time to time for use in connection
with the sale of Trust Interests such  information with respect to the Trust and
Trust Interests as EVD may reasonably request.  The Trust shall also furnish EVD
upon request with: (a) unaudited semiannual  statements of the Trust's books and
accounts  prepared  by the  Trust,  and (b) from  time to time  such  additional
information  regarding the Trust's financial or regulatory  condition as EVD may
reasonably request.

         1.5 The Trust represents to EVD that all registration  statements filed
by the  Trust  with the  Commission  under  the 1940 Act with  respect  to Trust
Interests have been prepared in conformity with the requirements of such statute
and the rules and  regulations  of the  Commission  thereunder.  As used in this
Agreement  the  term  "registration   statement"  shall  mean  any  registration
statement  filed with the Commission as modified by any amendments  thereto that
at any time shall have been  filed  with the  Commission  by or on behalf of the
Trust. The Trust represents and warrants to EVD that any registration  statement
will contain all  statements  required to be stated  therein in conformity  with
both such  statute and the rules and  regulations  of the  Commission;  that all
statements  of fact  contained in any  registration  statement  will be true and
correct  in all  material  respects  at the time of filing of such  registration
statement or amendment thereto; and that no registration  statement will include
an untrue statement of a material fact or omit to state a material fact required
to be stated therein or necessary to make the statements  therein not misleading
to a purchaser of Trust  Interests.  The Trust may but shall not be obligated to
propose from time to time such amendment to any registration statement as in the
light of future  developments  may, in the opinion of the  Trust's  counsel,  be
necessary or  advisable.  If the Trust shall not propose such  amendment  and/or
supplement  within fifteen days after receipt by the Trust of a written  request
from EVD to do so, EVD may, at its option,  terminate this Agreement.  The Trust
shall not file any amendment to any  registration  statement  without giving EVD
reasonable notice thereof in advance; provided,  however, that nothing contained
in this  Agreement  shall in any way limit the Trust's right to file at any time
such amendment to any  registration  statement as the Trust may deem  advisable,
such right being in all respects absolute and unconditional.

         1.6 The Trust  agrees to  indemnify,  defend and hold EVD,  its several
officers  and  directors,  and any person who controls EVD within the meaning of
Section 15 of the 1933 Act or Section 20 of the  Securities  and Exchange Act of
1934 (the  "1934  Act")  (for  purposes  of this  paragraph  1.6,  collectively,
"Covered  Persons")  free and  harmless  from and  against  any and all  claims,
demands,  liabilities  and  expenses  (including  the cost of  investigating  or
defending such claims,  demands or liabilities  and any counsel fees incurred in
connection therewith) which any Covered Person may incur under the 1933 Act, the
1934  Act,  common  law or  otherwise,  arising  out of or based  on any  untrue
statement of a material fact contained in any  registration  statement,  private
placement memorandum or other offering material ("Offering Material") or arising
out of or based on any omission to state a material  fact  required to be stated
in any Offering  Material or necessary  to make the  statements  in any Offering
Material  not  misleading;  provided,  however,  that the Trust's  agreement  to
indemnify  Covered  Persons  shall not be deemed to cover any  claims,  demands,
liabilities or expenses arising out of any financial and other statements as are
furnished in writing to the Trust by EVD in its capacity as Placement  Agent for
use in the  answers  to  any  items  of  any  registration  statement  or in any
statements  made in any  Offering  Material,  or arising  out of or based on any
omission or alleged  omission to state a material  fact in  connection  with the
giving of such information required to be stated in such answers or necessary to
make the answers not misleading; and further provided that the Trust's agreement
to indemnify EVD and the Trust's representations and warranties hereinbefore set
forth in this  paragraph  1.6 shall not be deemed to cover any  liability to the
Trust or its investors to which a Covered  Person would  otherwise be subject by
reason of willful misfeasance,  bad faith or gross negligence in the performance
of its duties,  or by reason of a Covered  Person's  reckless  disregard  of its
obligations and duties under this Agreement. The Trust should be notified of any
action brought  against a Covered  Person,  such  notification  to be given by a
writing addressed to the Trust, 24 Federal Street Boston,  Massachusetts  02110,
with a copy to the Adviser of the Portfolio,  Boston Management and Research, at
the same address,  promptly after the summons or other first legal process shall
have been duly and completely served upon such Covered Person. The failure to so
notify  the Trust of any such  action  shall  not  relieve  the  Trust  from any
liability  except to the extent the Trust  shall  have been  prejudiced  by such
failure,  or from any  liability  that the Trust may have to the Covered  Person
against  whom such action is brought by reason of any such untrue  statement  or
omission, otherwise than on account of the Trust's indemnity agreement contained
in this paragraph.  The Trust will be entitled to assume the defense of any suit
brought to enforce any such claim,  demand or  liability,  but in such case such
defense shall be conducted by counsel of good  standing  chosen by the Trust and
approved by EVD, which approval shall not be unreasonably withheld. In the event
the Trust  elects to assume the  defense of any such suit and retain  counsel of
good  standing  approved by EVD, the  defendant or defendants in such suit shall
bear the fees and expenses of any  additional  counsel  retained by any of them;
but in case the Trust does not elect to assume  the  defense of any such suit or
in case EVD  reasonably  does not  approve of counsel  chosen by the Trust,  the
Trust will reimburse the Covered Person named as defendant in such suit, for the
fees  and  expenses  of  any  counsel   retained  by  EVD  or  it.  The  Trust's
indemnification   agreement   contained  in  this   paragraph  and  the  Trust's
representations  and warranties in this Agreement shall remain  operative and in
full force and effect  regardless of any  investigation  made by or on behalf of
Covered  Persons,  and shall survive the delivery of any Trust  Interests.  This
agreement  of  indemnity  will inure  exclusively  to Covered  Persons and their
successors.  The Trust agrees to notify EVD promptly of the  commencement of any
litigation or  proceedings  against the Trust or any of its officers or Trustees
in connection with the issue and sale of any Trust Interests.

         1.7 EVD agrees to  indemnify,  defend and hold the Trust,  its  several
officers and trustees,  and any person who controls the Trust within the meaning
of Section 15 of the 1933 Act or  Section  20 of the 1934 Act (for  purposes  of
this paragraph 1.7, collectively,  "Covered Persons") free and harmless from and
against any and all claims,  demands,  liabilities  and expenses  (including the
costs of  investigating or defending such claims,  demands,  liabilities and any
counsel fees incurred in connection  therewith)  that Covered  Persons may incur
under the 1933 Act,  the 1934 Act or common  law or  otherwise,  but only to the
extent that such  liability or expense  incurred by a Covered  Person  resulting
from  such  claims  or  demands  shall  arise  out of or be based on any  untrue
statement of a material fact  contained in  information  furnished in writing by
EVD in its  capacity as  Placement  Agent to the Trust for use in the answers to
any of the items of any registration statement or in any statements in any other
Offering  Material or shall arise out of or be based on any  omission to state a
material fact in connection with such information furnished in writing by EVD to
the Trust  required  to be  stated in such  answers  or  necessary  to make such
information not misleading.  EVD shall be notified of any action brought against
a Covered Person, such notification to be given by a writing addressed to EVD at
24 Federal Street,  Boston,  Massachusetts 02110,  promptly after the summons or
other first legal process shall have been duly and  completely  served upon such
Covered Person.  EVD shall have the right of first control of the defense of the
action with counsel of its own choosing satisfactory to the Trust if such action
is based solely on such alleged  misstatement  or omission on EVD's part, and in
any other event each Covered  Person shall have the right to  participate in the
defense or  preparation  of the  defense of any such  action.  The failure to so
notify EVD of any such action shall not relieve EVD from any liability except to
the extent the Trust shall have been  prejudiced  by such  failure,  or from any
liability  that EVD may have to Covered  Persons by reason of any such untrue or
alleged untrue  statement,  or omission or alleged  omission,  otherwise than on
account of EVD's indemnity agreement contained in this paragraph.

         1.8 No Trust  Interests  shall be  offered  by either  EVD or the Trust
under any of the  provisions of this Agreement and no orders for the purchase or
sale of Trust Interests  hereunder shall be accepted by the Trust if and so long
as the effectiveness of the registration  statement or any necessary  amendments
thereto  shall be suspended  under any of the  provisions of the 1933 Act or the
1940 Act; provided,  however,  that nothing contained in this paragraph shall in
any way restrict or have an application to or bearing on the Trust's  obligation
to redeem Trust Interests from any investor in accordance with the provisions of
the Trust's registration statement or Declaration of Trust, as amended from time
to time.

         1.9 The Trust agrees to advise EVD as soon as reasonably practical by a
notice in writing delivered to EVD or its counsel:

          a) of any request by the  Commission  for  amendments to the 
registration statement then in effect or for additional information;

         (b) in the event of the  issuance by the  Commission  of any stop order
suspending the effectiveness of the registration statement then in effect or the
initiation  by  service  of  process  on the  Trust of any  proceeding  for that
purpose;

         (c) of the  happening of any event that makes untrue any statement of a
material fact made in the registration statement then in effect or that requires
the  making  of a change  in such  registration  statement  in order to make the
statements therein not misleading; and

         (d) of all action of the  Commission  with respect to any  amendment to
any  registration  statement  that  may  from  time to time be  filed  with  the
Commission.

         For purposes of this paragraph 1.9, informal requests by or acts of the
Staff of the  Commission  shall  not be deemed  actions  of or  requests  by the
Commission.

         1.10  EVD  agrees  on  behalf  of  itself  and its  employees  to treat
confidentially and as proprietary information of the Trust all records and other
information  not  otherwise  publicly  available  relative  to the Trust and its
prior,  present  or  potential  investors  and  not  to  use  such  records  and
information for any purpose other than performance of its  responsibilities  and
duties hereunder,  except after prior notification to and approval in writing by
the Trust,  which  approval  shall not be  unreasonably  withheld and may not be
withheld where EVD may be exposed to civil or criminal contempt  proceedings for
failure  to  comply,   when  requested  to  divulge  such  information  by  duly
constituted authorities, or when so requested by the Trust.

         2.  Duration and Termination of this Agreement.

         This Agreement  shall become  effective upon the date of its execution,
and, unless terminated as herein provided, shall remain in full force and effect
through and  including  February  28, 1998 and shall  continue in full force and
effect  indefinitely  thereafter,  but  only so long as such  continuance  after
February 28, 1998 is specifically approved at least annually (i) by the Board of
Trustees  of the  Trust  or by  vote of a  majority  of the  outstanding  voting
securities of the Trust and (ii) by the vote of a majority of those  Trustees of
the Trust who are not interested persons of EVD or the Trust cast in person at a
meeting called for the purpose of voting on such approval.

         Either party hereto may, at any time on sixty (60) days' prior  written
notice to the  other,  terminate  this  agreement  without  the  payment  of any
penalty, by action of Trustees of the Trust or the Directors of EVD, as the case
may be,  and the  Trust  may,  at any time  upon  such  written  notice  to EVD,
terminate  this  Agreement  by  vote of a  majority  of the  outstanding  voting
securities of the Trust.  This Agreement  shall terminate  automatically  in the
event of its assignment.

         3.  Representations and Warranties.

         EVD and the Trust each hereby represents and warrants to the other that
it has all requisite authority to enter into,  execute,  deliver and perform its
obligations under this Agreement and that, with respect to it, this Agreement is
legal, valid and binding, and enforceable in accordance with its terms.

         4.  Limitation of Liability.

         EVD expressly acknowledges the provision in the Declaration of Trust of
the Trust (Sections 5.2 and 5.6) limiting the personal liability of the Trustees
and officers of the Trust,  and EVD hereby agrees that it shall have recourse to
the Trust for  payment of claims or  obligations  as  between  the Trust and EVD
arising out of this Agreement and shall not seek  satisfaction  from any Trustee
or officer of the Trust.

         5.  Certain Definitions.

         The terms "assignment" and "interested  persons" when used herein shall
have the respective  meanings specified in the Investment Company Act of 1940 as
now in effect or as hereafter  amended subject,  however,  to such exemptions as
may be granted by the Securities and Exchange Commission by any rule, regulation
or order.  The term "vote of a majority of the  outstanding  voting  securities"
shall mean the vote, at a meeting of Holders, of the lesser of (a) 67 per centum
or more of the  Interests in the Trust  present or  represented  by proxy at the
meeting if the Holders of more than 50 per centum of the  outstanding  Interests
in the Trust are present or  represented  by proxy at the  meeting,  or (b) more
than  50 per  centum  of the  outstanding  Interests  in the  Trust.  The  terms
"Holders" and  "Interests"  when used herein shall have the respective  meanings
specified in the Declaration of Trust of the Trust.

         6.  Concerning Applicable Provisions of Law, etc.

         This Agreement  shall be subject to all  applicable  provisions of law,
including the  applicable  provisions of the 1940 Act and to the extent that any
provisions herein contained conflict with any such applicable provisions of law,
the latter shall control.

         The laws of the  Commonwealth  of  Massachusetts  shall,  except to the
extent  that any  applicable  provisions  of federal  law shall be  controlling,
govern  the  construction,  validity  and  effect  of  this  Agreement,  without
reference to principles of conflicts of law.

         If the  contract  set forth  herein  is  acceptable  to you,  please so
indicate by executing the enclosed copy of this Agreement and returning the same
to the undersigned, whereupon this Agreement shall constitute a binding contract
between  the  parties  hereto  effective  at the closing of business on the date
hereof.

                                            Yours very truly,

                                            WORLDWIDE HEALTH SCIENCES  PORTFOLIO




                                           By: /s/ James B. Hawkes
                                              President

Accepted:

EATON VANCE DISTRIBUTORS, INC.


By:  /s/ Wharton P. Whitaker
         President



                ACCOUNTING AND INTERESTHOLDER SERVICES AGREEMENT


         AGREEMENT  made as of this 24th day of June,  1996,  between  Worldwide
Health Sciences Portfolio, a New York trust (the "Trust"), and IBT Fund Services
(Canada) Inc., an Ontario corporation ("IBT").

         WHEREAS,  the Trust is registered  under the Investment  Company Act of
1940 as an open-end  management  investment company and desires to engage IBT to
provide certain trust accounting and interestholder  recordkeeping services with
respect to the Trust and IBT has indicated its willingness to so act, subject to
the terms and conditions of this Agreement.

         NOW  THEREFORE,  in  consideration  of the  premises  and of the mutual
agreements contained herein, the parties hereto agree as follows:

     1. IBT Appointed.  The Trust hereby appoints IBT to provide the services as
hereinafter  described  and  IBT  agrees  to act as  such  upon  the  terms  and
conditions hereinafter set forth.

     2. Definitions.  Whenever used herein, the terms listed below will have the
following meaning:

     2.1 Authorized Person.  Authorized Person will mean any of the persons duly
authorized to give Proper  Instructions  or otherwise act on behalf of the Trust
by  appropriate  resolution  of its  Board,  and set forth in a  certificate  as
required by Section 3 hereof.

     2.2 Board. Board will mean the Board of Trustees of the Trust.

     2.3 Portfolio Security.  Portfolio Security will mean any security owned by
the Trust.

     2.4 Interests. Interests will mean participation interests of the Trust.

         3. Certification as to Authorized  Persons.  The Secretary or Assistant
Secretary  of the Trust will at all times  maintain  on file with IBT his or her
certification to IBT, in such form as may be acceptable to IBT, of (i) the names
and  signatures  of the  Authorized  Persons  and  (ii) the  names of the  Board
members,  it being  understood  that upon the  occurrence  of any  change in the
information  set  forth  in the most  recent  certification  on file  (including
without  limitation any person named in the most recent  certification who is no
longer an Authorized Person as designated  therein),  the Secretary or Assistant
Secretary of the Trust, will sign a new or amended  certification  setting forth
the change and the new,  additional or omitted names or signatures.  IBT will be
entitled to rely and act upon the most recent Officers'  Certificate given to it
by the Trust.

         4.  Maintenance of Records.  IBT will maintain  records with respect to
the services  provided by IBT  hereunder and will furnish the Trust daily with a
statement of condition of the Trust.  The books and records of IBT pertaining to
its  actions  under  this  Agreement  and  reports  by IBT  or  its  independent
accountants  concerning its accounting systems and internal  accounting controls
will be open to  inspection  and audit at  reasonable  times by  officers  of or
auditors  employed  by the  Trust,  and the  staff  of The U.S.  Securities  and
Exchange Commission,  and will be preserved by IBT in accordance with procedures
established by the Trust.

         IBT shall keep the books of account  and  render  statements  or copies
from time to time as  reasonably  requested by the  Treasurer  or any  executive
officer of the Trust.

         IBT,  as  fund  accounting   agent,   shall  assist  generally  in  the
preparation  of reports of a financial  nature to Holders and others,  audits of
accounts, and other ministerial matters of like nature.

         5. Duties of Bank with Respect to Books of Account and  Calculations of
Net Asset Value.  Inasmuch as the Trust is treated as a partnership  for federal
income tax  purposes,  the Bank shall as Agent keep and  maintain  the books and
records of the Trust in  accordance  with the  Procedures  for  Allocations  and
Distributions adopted by the Trustees of the Trust, as such Procedures may be in
effect from time to time. A copy of the current  Procedures  is attached to this
Agreement,  and the  Trust  agrees  promptly  to  furnish  all  revisions  to or
restatements of such Procedures to the Bank.

         The Bank shall as Agent keep such books of account  (including  records
showing the adjusted tax costs of the Trust's  portfolio  securities) and render
as at the close of  business  on each day a detailed  statement  of the  amounts
received or paid out and of securities  received or delivered for the account of
the Trust  during  said day and such other  statements,  including a daily trial
balance and  inventory of the Trust's  portfolio  securities;  and shall furnish
such other financial  information and data as from time to time requested by the
Treasurer  or any  executive  officer  of  the  Trust;  and  shall  compute  and
determine,  as of the close of  business of the New York Stock  Exchange,  or at
such other time or times as the Board may determine,  the net asset value of the
Trust and the net asset value of each interest in the Trust,  such  computations
and determinations to be made in accordance with the governing  documents of the
Trust and the votes and instructions of the Board and of the investment  adviser
at the time in force  and  applicable,  and  promptly  notify  the Trust and its
investment adviser and such other persons as the Trust may request of the result
of such computation and determination.  In computing the net asset value IBT may
rely upon security quotations received by telephone or otherwise from sources or
pricing services designated by the Trust by proper instructions, and may further
rely upon  information  furnished to it by any  authorized  officer of the Trust
relative (a) to  liabilities of the Trust not appearing on its books of account,
(b) to the  existence,  status and proper  treatment of any reserve or reserves,
(c) to any  procedures  or  policies  established  by the  Board  regarding  the
valuation of portfolio  securities or other  assets,  and (d) to the value to be
assigned to any bond,  note,  debenture,  Treasury bill,  repurchase  agreement,
subscription right, security, participation interests or other asset or property
for which market  quotations are not readily  available.  IBT shall also compute
and  determine at such time or times as the Trust may  designate  the portion of
each item which has  significance  for a holder of an  interest  in the Trust in
computing and determining its U.S. federal income tax liability  including,  but
not limited to, each item of income, expense and realized and unrealized gain or
loss of the Trust which is attributable  for Federal income tax purposes to each
such holder.

         6.  Interestholder Services. IBT shall keep appropriate records of the
holdings  of each  interestholder  on a daily  basis.  IBT shall  also keep each
interestholder's subscription agreement with the Portfolio.

         7.  Compensation  of  IBT.  For the  services  to be  rendered  and the
facilities provided by IBT hereunder,  the Trust shall pay to IBT a fee from the
assets of the Trust computed and paid monthly, in accordance with a fee schedule
agreed upon and attached hereto,  as the same may be changed by mutual agreement
of the parties from time to time.

         8.       Concerning IBT.

                  8.1  Performance of Duties and Standard of Care. IBT shall not
be liable for any error of judgment or mistake of law or for any act or omission
in the performance of its duties hereunder, except for willful misfeasance,  bad
faith or gross negligence in the performance of its duties,  or by reason of its
reckless disregard of its obligations and duties hereunder.

         IBT will be entitled to receive and act upon the advice of  independent
counsel of its own  selection,  which may be counsel for the Trust,  and will be
without  liability  for any action  taken or thing done or omitted to be done in
accordance with this Agreement in good faith in conformity with such advice.  In
the  performance  of its  duties  hereunder,  IBT will be  protected  and not be
liable,  and  will  be  indemnified  and  held  harmless  by the  Trust  for any
reasonable action taken or omitted to be taken by it in good faith reliance upon
the  terms  of  this  Agreement,  any  Officers'  Certificate,  and  or  written
instructions  received  from an  Authorized  Person,  resolution  of the  Board,
telegram,  notice, request,  certificate or other instrument reasonably believed
by IBT to be genuine  and for any other loss to the Trust  except in the case of
IBT's gross negligence,  willful  misfeasance or bad faith in the performance of
its duties or reckless disregard of its obligations and duties hereunder.

         Notwithstanding anything in this Agreement to the contrary, in no event
shall IBT be liable hereunder or to any third party:

     (a) for any  losses  or  damages  of any kind  resulting  from acts of God,
earthquakes,  fires, floods, storms or other disturbances of restrictions,  acts
of war,  civil  war or  terrorism,  insurrection,  nuclear  fusion,  fission  or
radiation, the interruption,  loss or malfunction or utilities,  transportation,
or computers (hardware or software) and computer facilities,  the unavailability
of energy sources and other similar  happenings or events except as results from
IBT's own gross negligence,  willful misfeasance or bad faith in the performance
of its duties; or

     (b) for  special,  punitive  or  consequential  damages  arising  from  the
provision of services hereunder, even if IBT has been advised of the possibility
of such damages.

                  8.2 Subcontractors. IBT, subject to approval of the Trust, may
subcontract for the performance of IBT's  obligations  hereunder with any one or
more  persons,  provided,  however,  that unless the Trust  otherwise  expressly
agrees in writing,  IBT shall be as fully  responsible to the Trust for the acts
and omissions of any subcontractor as it would be for its own acts or omissions.
In the event IBT obtains a judgment,  settlement or other monetary  recovery for
the wrongful conduct of the  subcontractor,  the Trust shall be entitled to such
recovery  if such  conduct  resulted  in a loss to the Trust  and IBT  agrees to
pursue such claims  vigorously.  To the extent  possible,  such  sub-contractors
shall provide services outside the United States.

                  8.3  Activities  of IBT. The  services  provided by IBT to the
Trust  are  not  to  be  deemed  to be  exclusive,  IBT  being  free  to  render
administrative,  fund accounting  and/or other services to other parties.  It is
understood that members of the Board,  officers,  and  shareholders of the Trust
are or may become  similarly  interested in the Trust and that IBT and/or any of
its affiliates may become  interested in the Trust as a shareholder of the Trust
or otherwise.

                8.4 Insurance.  IBT need not maintain any special insurance for
 the benefit of the  Trust,  but  will  maintain  customary  insurance  for 
its  obligations hereunder.

         9.  Termination.  This  Agreement may be terminated at any time without
penalty upon sixty days written notice delivered by either party to the other by
means of  registered  mail,  and upon the  expiration  of such sixty days,  this
Agreement will  terminate.  At any time after the termination of this Agreement,
the Trust will have access to the records of IBT relating to the  performance of
its duties  hereunder and IBT shall cooperate in the transfer of such records to
its successor.

         10.  Confidentiality.  Both parties  hereto  agree that any  non-public
information  obtained  hereunder  concerning the other party is confidential and
may not be disclosed to any other person without the consent of the other party,
except as may be required by applicable  law or at the request of a governmental
agency.  The  parties  further  agree  that a  breach  of this  provision  would
irreparably  damage the other party and  accordingly  agree that each of them is
entitled,  without bond or other  security,  to an injunction or  injunctions to
prevent breaches of this provision.

     11.  Notices.  Any  notice or other  instrument  in writing  authorized  or
required  by  this  Agreement  to be  given  to  either  party  hereto  will  be
sufficiently  given if  addressed to such party and mailed or delivered to it at
its office at the address set forth below; namely:

(a)  In the case of notices sent to the Trust to:

C/O The Bank of Nova Scotia Trust Company (Cayman) Ltd.
The Bank of Nova Scotia Building
P. O. Box 501
George Town
Grand Cayman, Cayman Island
British West Indies

(b)  In the case of notices sent to IBT to:

IBT Fund Services (Canada), Inc.
Suite 5850, One First Canadian Place
P. O. Box 231
Toronto, Ontario M5X 1A4
Attention:  Robert Donahoe

or at such other place as such party may from time to time designate in writing.

     12. Amendments.  This Agreement may not be altered or amended, except by an
instrument in writing,  executed by both parties,  and in the case of the Trust,
duly authorized and approved by its respective Board.

     13. Governing Law. This Agreement will be governed by the laws of Ontario.

     14.  Counterparts.  This  Agreement  may  be  executed  in  any  number  of
counterparts,  each of  which  shall  be  deemed  to be an  original,  but  such
counterparts shall, together, constitute only one instrument.

         IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
executed by their  respective  officers  thereunto duly authorized as of the day
and year first written above.


                                            Worldwide Health Sciences Portfolio


                                             By:/s/ James B. Hawkes
                                                     Name:  James B. Hawkes
                                                     Title:  President


ATTEST:


/s/ H. Day Brigham, Jr.


                                         IBT Fund Services (Canada), Inc.

         
                                         By:/s/ Robert V. Donahoe II
                                         Name:  Robert V. Donahoe II
                                         Title: Director
                                         signed in Toronto, Ontario, Canada


ATTEST:

/s/ Neal Nenadovic



DATE:  June 24, 1996









                          SUB-ADMINISTRATION AGREEMENT

THIS AGREEMENT is made as of the 24th day of June, 1996.

     AMONG:  

     (1)  Eaton  Vance   Management,   a   Massachusetts   business  trust  (the
"Administrator),

     (2) Worldwide  Health  Sciences  Portfolio,  a New York trust the principal
office of which is at IBT Trust Company  (Cayman),  Ltd, The Bank of Nova Scotia
Building,  George Town,  Grand Cayman,  Cayman Island,  British West Indies (the
"Trust"),

     AND 

     (3) IBT Trust Company  (Cayman),  Ltd., a company duly  incorporated in the
Cayman  Islands  the  Registered  Office of which is at The Bank of Nova  Scotia
Building,  George  Town,  Grand  Cayman,  Cayman  Islands,  British  West Indies
aforesaid (the "Sub-Administrator").

WHEREAS:

         (A)      The Trust is  registered  under the United  States  Investment
                  Company Act of 1940 as a management investment company.

         (B)      The  Administrator  pursuant  to an  Administration  Agreement
                  dated   June  24,   1996  has   agreed  to   provide   general
                  administration  services to the Trust,  and the  Administrator
                  and the Trust wish to appoint the Sub-Administrator as general
                  administrator  of the Trust outside the United States upon the
                  terms and conditions hereinafter appearing.

AGREEMENT:

     1. (a) In this  Agreement  the words  standing  in the first  column of the
table next hereinafter contained shall bear the meanings set opposite to them in
the second column thereof, if not inconsistent with the subject or context:

Words                            Meanings

"Declaration of Trust"         The Declaration of Trust of the Trust for the
                               time being in force.

"Trustees"                     The  Trustees of the Trust for the time  being,
                               or as the case may be, the Trustees assembled as
                               a board.

"Registration Statement"      The Registration Statement of the Trust as amended
                              and filed with the Securities and Exchange
                              Commission.

         (b)      Unless the context otherwise  requires and except as varied or
                  otherwise  specified in this agreement,  words and expressions
                  contained in this agreement  shall bear the same meaning as in
                  the  Registration  Statement  PROVIDED THAT any  alteration or
                  amendment of the Registration Statement shall not be effective
                  for the purposes of this  Agreement  unless the  administrator
                  shall by  endorsement  hereon or  otherwise  have  assented in
                  writing thereto.

     (c) The headings are intended for convenience only and shall not affect the
construction of this Agreement.




                          APPOINTMENT OF ADMINISTRATOR

2.       The  Administrator  and the Trust hereby appoint the  Sub-Administrator
         and the Sub-Administrator hereby agrees to act as general administrator
         of the Trust,  acting solely outside the United  States,  in accordance
         with the terms and conditions hereof with effect from the date hereof.

                           DUTIES AS SUB-ADMINISTRATOR

3.       The Sub-Administrator shall from time to time deliver such information,
         explanations  and  reports  to the Trust as the  Trust  may  reasonably
         require regarding the conduct of the business of the Trust.

4.      The  Sub-Administrator  shall provide the principal office of the Trust;
and

         (a)      conduct on behalf of the Trust all the day to day  business of
                  the Trust  outside the United  States,  other than  investment
                  activities,  and provide or procure such office accommodation,
                  secretarial  staff and other facilities as may be required for
                  the purposes of fulfilling its duties under this Agreement;

          (b)     receive and approve notices of  subscriptions and redemptions
                  of Trust interests;

          (c)     review  and  arrange   execution  and  filing  with  the  U.S.
                  Securities and Exchange  Commission  (the "SEC") of amendments
                  to the  Trust's  Registration  Statement,  and  of  any  other
                  regulatory filings required to be made by the Trust which have
                  been prepared by the Administrator or the Trust;

         (d)      deal   with  and  reply  to  all   correspondence   and  other
                  communications addressed to the Trust at its principal office,
                  whether  in   relation  to  the   subscription,   purchase  or
                  redemption of interests in the Trust or otherwise PROVIDE THAT
                  in the event of any  dispute  in  connection  with the  issue,
                  ownership, redemption or otherwise of any interests the matter
                  shall be referred to the  Trustees  acting  outside the United
                  States,  and the  Sub-Administrator  shall take such action as
                  may reasonably be required by the Trust;

         (e)      at any time during business hours to permit any duly appointed
                  agent or  representative of the Administrator or the Trust, at
                  the expense of the  Administrator or the Trust, to inspect the
                  Register of Holders or any other  documents  or records in the
                  possession  of the  Sub-Administrator  and give such  agent or
                  representative   during   business   hours  all   information,
                  explanations  and  assistance as such agent or  representative
                  may reasonably require, and permit representatives of the U.S.
                  Securities  and  Exchange  Commission  to  examine  books  and
                  records of the Trust;

         (f)      maintain  and  safeguard  the Register of Holders of Interests
                  and other documents in connection  therewith and enter on such
                  Register  all  original  issues  and  allotments  of  and  all
                  increases, decreases and redemptions of such interests, all in
                  accordance with the provisions of the Declaration of Trust and
                  Trustee  instructions and to prepare all such lists of Holders
                  of  Interests  of the Trust and account  numbers of Holders as
                  may be required by the Trust.





                        DEALINGS OF THE SUB-ADMINISTRATOR

5.       Nothing herein  contained  shall prevent the  Sub-Administrator  or any
         firm,   person   or   company   associated   in  any   way   with   the
         Sub-Administrator from contracting with or entering into any financial,
         banking or other  transaction  with the Trust,  any  shareholder or any
         company or body of persons any of whose  securities  are held by or for
         the account of the Trust or from being interested in such transaction.

6.       Nothing herein  contained  shall prevent the  Sub-Administrator  or any
         associate  of the  Sub-Administrator  from acting as  administrator  or
         general corporate  manager or in any other capacity  whatsoever for any
         other company or body of persons on such terms as the Sub-Administrator
         or  such  associate  may  arrange,  and the  Sub-Administrator  or such
         associate  shall not be deemed to be  affected  with notice of or to be
         under any duty to  disclose  to the  Trust any fact or thing  which may
         come to its  knowledge  or that of any of its servants or agents in the
         course  of so doing or in any  manner  whatever  otherwise  than in the
         course of carrying out its duties hereunder.

                                AGENTS AND ADVICE

 7.       The  Sub-Administrator  shall be at liberty in the performance of
          its duties and in the exercise of any of the powers  vested in it
          hereunder to act by responsible officers or a responsible officer
          for the time  being and to  employ  and pay an agent who may (but
          need not) be an associate of the  Sub-Administrator to perform or
          concur in performing any of the services required to be performed
          hereunder  and may act or rely upon the  opinion or advice or any
          information obtained from any broker, lawyer,  valuer,  surveyor,
          auctioneer or other expert,  whether  reporting to the Trust,  to
          the  Administrator  to the  Sub-Administrator,  or  not,  and the
          Sub-Administrator   shall  not  be   responsible   for  any  loss
          occasioned by its so acting.  Any officer or agent acting for the
          Sub-Administrator  on behalf of the Trust shall act only  outside
          the United States,  to the extent required by U.S. tax law. It is
          understood and agreed that until IBT Trust Company (Cayman), Ltd.
          has received its  administrator's  license in the Cayman Islands,
          The Bank of Nova Scotia Trust Company (Cayman) Ltd. shall perform
          the  functions  of  the   Sub-Administrator  set  forth  in  this
          Agreement.

8.       The  Sub-Administrator may at the expense of the Adminstrator refer any
         legal question to the legal advisers of the  Administrator or the Trust
         for the time being  (whose  name shall from time to time be notified by
         or  on   behalf   of   the   Administrator   or   the   Trust   to  the
         Sub-Administrator)  or legal advisers that it may select with the prior
         approval of the  Administrator  or the Trust and may authorize any such
         legal  adviser  to  take  the  opinion  of  counsel  on any  matter  of
         difficulty  and may act on any opinion given by such legal  advisers or
         counsel without being  responsible  for the correctness  thereof or for
         any result which may follow from so doing.

                                  REMUNERATION

9.       In  consideration  of the services  performed by the  Sub-Administrator
         hereunder the  Sub-Administrator  shall be entitled to receive from the
         Administrator  fees  as  are  agreed  upon  by  the  Administrator  and
         Sub-Administrator and set forth in Schedule A of this Agreement.

           REIMBURSEMENT BY THE ADMINISTRATOR TO THE SUB-ADMINISTRATOR

10.      In  addition  to the fees set out in clause 9 above  the  Administrator
         shall  reimburse  to the  Sub-Administrator  all  reasonable  costs and
         expenses  incurred by the  Sub-Administrator  in the performance of its
         duties hereunder.


<PAGE>


                             LIABILITY AND INDEMNITY

11.  (a) The Sub-Administrator, its subsidiaries, agents, advisors,
 shareholders,  directors,  officers,  servants  and  employees
 shall  not be liable  to the  Administrator  or the Trust or a
 Holder  of  Interests  in the  Trust,  or any of its or  their
 successors  or  assigns,   except  for  loss  arising  to  the
 Administrator  or the Trust by reason of act of, or  omissions
 due to negligence  or willful  default on the part of any such
 persons as aforesaid.

     (b) The  Administrator  and the  Trust  shall  indemnify,  defend  and hold
harmless the Sub-Administrator and each of its subsidiaries,  agents,  advisors,
shareholders,  directors,  officers, servants and employees from and against any
loss, liability,  damage, cost or expense (including legal fees and expenses and
any  amounts  paid in  settlement),  resulting  from  its or  their  actions  or
capacities   hereunder  or  otherwise  concerning  the  business  or  activities
undertaken on behalf of the  Administrator  or the Trust under this Agreement or
sustained by any of them including  (without  restricting  the generality of the
foregoing)  loss  sustained  as a  result  of  delay,  mis-delivery  or error in
transmission of any cable, telefax, telex or telegraphic communication.  Subject
as aforesaid all actions taken by the  Sub-Administrator  shall be taken in good
faith  and in the  reasonable  belief  that such  actions  are taken in the best
interests of the Trust  PROVIDED  THAT  termination  of any action,  proceeding,
demand, claim or lawsuit by judgment,  order or settlement shall not, or itself,
create a  presumption  that the conduct in question was not  undertaken  in good
faith with due care and in a manner reasonably  believed to be in or not opposed
to the best interest of the Trust. The right of indemnification  hereunder shall
remain in full force and effect  regardless of the  expiration or termination of
this Agreement.

                 RIGHT TO ADVISE AND MANAGE THE FUNDS OR OTHERS

12.      The  Administrator  or the Trust  acknowledge that an important part of
         the Sub-Administrator's  business is, and that it derives profits from,
         managing the affairs of its  affiliates and other entities and that the
         Sub-Administrator  will be managing such affiliates and entities during
         the same  period  that it is  managing  the  affairs of the Trust.  The
         Sub-Administrator  and its  officers  and  employees  shall  be free to
         manage such other  affiliates and entities and to retain for its own or
         their benefit all profits and revenues derived therefrom  PROVIDED THAT
         the  Sub-Administrator  shall not  knowingly  prefer  affiliates of the
         Sub-Administrator  or other entities to the detriment of the affairs of
         the Trust.

                                  RESTRICTIONS

13.      None of the parties hereto shall do or commit any act,  matter or thing
         which would or might  prejudice  or bring into  disrepute in any manner
         the business or  reputation  of the other or any  director,  officer or
         employee of the other.

14.      Except  as  required  by  the  law  and  save  as  contemplated  by the
         Declaration of Trust, none of the parties hereto shall either before or
         after the  termination  of this  Agreement  disclose  to any person not
         authorized by the other party to receive the same information  relating
         to such  party or to the  affairs  of such  party of  which  the  party
         disclosing  the same shall have become  possessed  during the period of
         this agreement,  and both parties shall use all reasonable endeavors to
         prevent any such disclosure as aforesaid.


<PAGE>


                                   TERMINATION

     15. The  Sub-Administrator  shall be  entitled  to resign  its  appointment
hereunder:

     (a) by  giving  not less than two (2)  months'  notice  in  writing  to the
Administrator and the Trust;

         (b)      if the  Administrator  or the Trust shall commit any breach of
                  its obligations under this Agreement and shall fail within ten
                  days of  receipt  of notice  served  by the  Sub-Administrator
                  requiring it so to do, to make good such breach; and

         (c)      at  any  time  without  such  notice  as  is  referred  to  in
                  sub-paragraphs (a) and (b) of this clause if the Administrator
                  or the Trust  shall go into  liquidation  (other  than for the
                  purpose  of   reconstruction   or   amalgamation   upon  terms
                  previously approved in writing by the Sub-Administrator) or if
                  a receiver  of any of the assets of the  Administrator  or the
                  Trust is appointed.

     16. The  Administator  or the Trust may  terminate the  appointment  of the
Sub-Administrator:

          (a)  by giving no less than two (2)  months'  notice in writing to the
               Sub-Administrator;

         (b)      if  the  Sub-Administrator  shall  commit  any  breach  of its
                  obligations  under this  Agreement  and shall fail  within ten
                  days of receipt of notice served by the  Administrator  or the
                  Trust requiring it so to do, to make good such breach; and

         (c)      at  any  time  without  such  notice  as  is  referred  to  in
                  sub-paragraphs   (a)   and   (b)  or   this   clause   if  the
                  Sub-Administrator  goes into  liquidation  (except a voluntary
                  liquidation for the purpose of  reconstruction or amalgamation
                  upon terms previously approved in writing by the Administrator
                  and the Trust) or if a  receiver  is  appointed  of any of the
                  assets of the Sub-Administrator.

17.      On termination of the  appointment of the  Sub-Administrator  under the
         provisions of the preceding clauses,  such termination shall be without
         prejudice to any  antecedent  liability of the  Sub-Administrator,  the
         Administrator or the Trust. The Sub-Administrator  shall be entitled to
         receive  all  fees  and  other  moneys  accrued  up to the date of such
         termination  but shall not be  entitled to  compensation  in respect of
         such termination.

18.      The Sub-Administrator shall, on the termination of its appointment:

     (a) Forthwith  hand over to the  Administrator  or the Trust or as it shall
direct all books of account,  registers,  correspondence  and records of all and
every  description  relating  to the  affairs  of  the  Trust  which  are in the
Sub-Administrator's  possession  but  not  including  any  promotional  material
bearing  the style or any trade  mark or  symbol of the  Sub-Administrator.  The
Sub-Administrator  shall  also in  such  circumstance  deliver  or  cause  to be
delivered to the succeeding  Sub-Administrator  or as the  Administrator  or the
Trust shall direct all funds or other  properties of the Trust deposited with or
otherwise  held by the  Sub-Administrator  or to its order  hereunder and do all
such further acts as the  Administrator  or the Trust may reasonably  require of
it.



<PAGE>


     (b)  have  the  right  by  written  request  to  require  the  Trust in its
Registration  Statement and any other  material made  available to investors and
prospective   investors   to   (as   may   reasonably   be   approved   by   the
Sub-Administrator)  indicate that the  Sub-Administrator and its delegate(s) (if
any) have ceased to be its Sub-Administrator.

                         REPRESENTATIONS AND WARRANTIES


     19. (a) The Sub-Administrator  represents and warrants to the Administrator
and the Trust as follows:

                  (i)      The Sub-Administrator has full power and authority to
                           enter  into  and  perform  this  Agreement  and  this
                           Agreement  has been duly  authorized by all requisite
                           corporate  action,  executed  and  delivered by or on
                           behalf of the  Sub-Administrator  and  constitutes  a
                           valid and binding agreement of the Sub-Administrator.

                  (ii)     Neither the  execution,  delivery nor  performance of
                           this Agreement by the  Sub-Administrator  will result
                           in a breach of violation of any statute, law, rule or
                           of the material  provisions of any debenture or other
                           material agreement binding upon the Sub-Administrator
                           and no consent, approval, authorization or license by
                           any court or governmental  agency is required for the
                           execution,  delivery or performance of this Agreement
                           by the  Sub-Administrator,  except  such as have been
                           obtained by the Sub-Administrator.

     (b)  the   Administrator  and  the  Trust  represent  and  warrant  to  the
Sub-Administrator as follows:

                  (i)      The  Administrator  and the Trust have full power and
                           authority  to enter into and perform  this  Agreement
                           and this  Agreement  has been duly  authorized by all
                           requisite corporate action, executed and delivered by
                           or on behalf of the  Administrator  and the Trust and
                           constitutes  a valid  and  binding  agreement  of the
                           Administrator and the Trust.

                  (ii)     Neither the  execution,  delivery nor  performance of
                           this  Agreement  by the  Administrator  and the Trust
                           will result in a breach of  violation of any statute,
                           law,  rule  or of  the  material  provisions  of  any
                           debentures or other material  agreement  binding upon
                           the  Administrator  and  the  Trust  and no  consent,
                           approval,  authorization  or  license by any court or
                           governmental  agency is required  for the  execution,
                           delivery  or  performance  of this  Agreement  by the
                           trust  except  such  as  have  been  obtained  by the
                           Administrator and the Trust.

                             INDEPENDENT CONTRACTOR

20.      For all purposes of this Agreement,  the Sub-Administrator  shall be an
         independent  contractor  and not an employee or dependent  agent of the
         Administrator  or the Trust,  nor shall anything herein be construed as
         making the Administrator or the Trust a partner or co-venturer with the
         Sub-Administrator or any of its affiliates or other clients.  Except as
         provided  in  this  Agreement,  the  Sub-Administrator  shall  have  no
         authority  to bind,  obligate or  represent  the  Administrator  or the
         Trust.


<PAGE>


                               COMPLETE AGREEMENT

     21.  This  Agreement  constitutes  the entire  agreement  among the parties
relating to the subject matter hereof.


                                   ASSIGNMENT

22.      This  Agreement  shall be  binding  upon the  parties  hereto and their
         respective  successors and assigns but may not be assigned by any party
         without the express  written consent of the other party which shall not
         be reasonably withheld or delayed.

     23. This Agreement may not be amended except by the written consent of each
of the parties hereto.

                                     NOTICES

24.      Any notice  delivered  under  this  agreement  shall be in writing  and
         signed by a duly authorized officer of the party giving such notice and
         shall be delivered  personally or sent by registered or certified mail,
         postage prepaid,  to the registered  office of the party for whom it is
         intended.  A notice  so  posted  shall be  deemed  to be  served at the
         expiration  of  seventy-two  (72) hours  after  posting  and in proving
         service  by post it  shall be  sufficient  to  prove  that an  envelope
         containing the notice was duly addressed, stamped and posted.

                                  GOVERNING LAW

25.      This  Agreement  shall be governed by and construed in accordance  with
         the laws of the Cayman  Islands and the parties  hereto agree to submit
         to the non-exclusive jurisdiction of the Courts of the Cayman Islands.

IN WITNESS WHEREOF this Agreement has been duly executed for an on behalf of the
parties hereto in manner binding upon them the day and year first above written:
written.

Signed by
for and on behalf of the said
Eaton Vance Management                               /s/ H. Day Brigham, Jr.
                                                              Vice President

in the presence of:
Signed by
for and on behalf of the said
Worldwide Health Sciences Portfolio:                /s/ James B. Hawkes
                                                        President

                                                    signed in Hamilton, Bermuda

SIGNED by
for and on behalf of the said
IBT Trust Company (Cayman), Ltd.:                    /s/ Robert V. Donahoe, II
                                                     Director
                                                    signed in Toronto, Ontario

<PAGE>


                        IBT Trust Company (Cayman), Ltd.
                  Fee Schedule for Sub-Administration Services
                                   Eaton Vance



     Annual Offshore Sub-Administration Fee          $ 1,500

         This fee will be charged  annually for the following  Principal  Office
and Sub-Administrative services.


         Principal Office

         The following services will be provided for the Portfolio (Hub):

                  o Register Portfolio/Fund with Inspector of Financial Services
                  o Safekeeping  of original  contracts,  agreements,  and board
                  minutes o Provide  officers to Fund o Ensure  compliance  with
                  Cayman Islands Law

         Administrative Services

The following services will be provided for the Portfolio (Hub):

                  o Authorize  expense budget and amendments o Authorize expense
                  payments  o  Mail  Board  materials  o  Maintain   shareholder
                  register o Authorize Subscriptions and redemptions o Authorize
                  Fund distributions (if Applicable)
                  o Distribute annual, semi-annual, quarterly reports to
                    shareholders





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