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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(AMENDMENT NO. 1 )*
ArQule, Inc.
----------------------------------------------------------
(Name of Issuer)
Common Stock, $.01 par value
----------------------------------------------------------
(Title of Class of Securities)
00004269E1
----------------------------------------------------------
(CUSIP Number)
*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which would
alter the disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not
be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
the Act but shall be subject to all other provisions of the Act (however, see
the Notes).
Page 1 of 22 Pages
<PAGE> 2
CUSIP NO. 00004269E1 13G PAGE 2 OF 22 PAGES
---------- --- ----
- --------------------------------------------------------------------------------
1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Atlas Venture Fund II, L.P.
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
- --------------------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware Limited Partnership
- --------------------------------------------------------------------------------
5. SOLE VOTING POWER
0 shares
NUMBER OF -------------------------------------------------------------
SHARES 6. SHARED VOTING POWER
BENEFICIALLY
OWNED BY 1,185,004 shares
EACH -------------------------------------------------------------
REPORTING 7. SOLE DISPOSITIVE POWER
PERSON
WITH 0 shares
-------------------------------------------------------------
8. SHARED DISPOSITIVE POWER
1,185,004 shares
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,185,004 shares
- --------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES* [ ]
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
10.0%
- --------------------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
PN
- --------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 2 of 22 Pages
<PAGE> 3
CUSIP NO. 00004269E1 13G PAGE 3 OF 22 PAGES
---------- --- ----
- --------------------------------------------------------------------------------
1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Atlas Venture Associates II, L.P.
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
- --------------------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware Limited Partnership
- --------------------------------------------------------------------------------
5. SOLE VOTING POWER
0 shares
NUMBER OF -------------------------------------------------------------
SHARES 6. SHARED VOTING POWER
BENEFICIALLY
OWNED BY 1,185,004 shares
EACH -------------------------------------------------------------
REPORTING 7. SOLE DISPOSITIVE POWER
PERSON
WITH 0 shares
-------------------------------------------------------------
8. SHARED DISPOSITIVE POWER
1,185,004 shares
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,185,004 shares
- --------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES* [ ]
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
10.0%
- --------------------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
PN
- --------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 3 of 22 Pages
<PAGE> 4
CUSIP NO. 00004269E1 13G PAGE 4 OF 22 PAGES
---------- --- ----
- --------------------------------------------------------------------------------
1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Christopher J. Spray
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
- --------------------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
United Kingdom
- --------------------------------------------------------------------------------
5. SOLE VOTING POWER
0 shares
NUMBER OF -------------------------------------------------------------
SHARES 6. SHARED VOTING POWER
BENEFICIALLY
OWNED BY 670,056 shares
EACH -------------------------------------------------------------
REPORTING 7. SOLE DISPOSITIVE POWER
PERSON
WITH 0 shares
-------------------------------------------------------------
8. SHARED DISPOSITIVE POWER
670,056 shares
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
670,056 shares
- --------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES* [ ]
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
5.6%
- --------------------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
IN
- --------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 4 of 22 Pages
<PAGE> 5
CUSIP NO. 00004269E1 13G PAGE 5 OF 22 PAGES
---------- --- ----
- --------------------------------------------------------------------------------
1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Barry Fidelman
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
- --------------------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- --------------------------------------------------------------------------------
5. SOLE VOTING POWER
0 shares
NUMBER OF -------------------------------------------------------------
SHARES 6. SHARED VOTING POWER
BENEFICIALLY
OWNED BY 670,056 shares
EACH -------------------------------------------------------------
REPORTING 7. SOLE DISPOSITIVE POWER
PERSON
WITH 0 shares
-------------------------------------------------------------
8. SHARED DISPOSITIVE POWER
670,056 shares
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
670,056 shares
- --------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES* [ ]
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
5.6%
- --------------------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
IN
- --------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 5 of 22 Pages
<PAGE> 6
CUSIP NO. 00004269E1 13G PAGE 6 OF 22 PAGES
---------- --- ----
- --------------------------------------------------------------------------------
1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Allan Ferguson
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
- --------------------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- --------------------------------------------------------------------------------
5. SOLE VOTING POWER
0 shares
NUMBER OF -------------------------------------------------------------
SHARES 6. SHARED VOTING POWER
BENEFICIALLY
OWNED BY 670,056 shares
EACH -------------------------------------------------------------
REPORTING 7. SOLE DISPOSITIVE POWER
PERSON
WITH 0 shares
-------------------------------------------------------------
8. SHARED DISPOSITIVE POWER
670,056 shares
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
670,056 shares
- --------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES* [ ]
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
5.6%
- --------------------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
IN
- --------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 6 of 22 Pages
<PAGE> 7
CUSIP NO. 00004269E1 13G PAGE 7 OF 22 PAGES
---------- --- ----
- --------------------------------------------------------------------------------
1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Jean-Francois Formela
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
- --------------------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
France
- --------------------------------------------------------------------------------
5. SOLE VOTING POWER
0 shares
NUMBER OF -------------------------------------------------------------
SHARES 6. SHARED VOTING POWER
BENEFICIALLY
OWNED BY 670,056 shares
EACH -------------------------------------------------------------
REPORTING 7. SOLE DISPOSITIVE POWER
PERSON
WITH 0 shares
-------------------------------------------------------------
8. SHARED DISPOSITIVE POWER
670,056 shares
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
670,056 shares
- --------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES* [ ]
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
5.6%
- --------------------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
IN
- --------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 7 of 22 Pages
<PAGE> 8
CUSIP NO. 00004269E1 13G PAGE 8 OF 22 PAGES
---------- --- ----
- --------------------------------------------------------------------------------
1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Atlas Venture Europe Fund B.V.
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
- --------------------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
The Netherlands
- --------------------------------------------------------------------------------
5. SOLE VOTING POWER
0 shares
NUMBER OF -------------------------------------------------------------
SHARES 6. SHARED VOTING POWER
BENEFICIALLY
OWNED BY 1,185,004 shares
EACH -------------------------------------------------------------
REPORTING 7. SOLE DISPOSITIVE POWER
PERSON
WITH 0 shares
-------------------------------------------------------------
8. SHARED DISPOSITIVE POWER
1,185,004 shares
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,185,004 shares
- --------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES* [ ]
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
10.0%
- --------------------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
CO
- --------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 8 of 22 Pages
<PAGE> 9
CUSIP NO. 00004269E1 13G PAGE 9 OF 22 PAGES
---------- --- ----
- --------------------------------------------------------------------------------
1. NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Atlas InvesteringsGroep N.V.
- --------------------------------------------------------------------------------
2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3. SEC USE ONLY
- --------------------------------------------------------------------------------
4. CITIZENSHIP OR PLACE OF ORGANIZATION
The Netherlands
- --------------------------------------------------------------------------------
5. SOLE VOTING POWER
0 shares
NUMBER OF -------------------------------------------------------------
SHARES 6. SHARED VOTING POWER
BENEFICIALLY
OWNED BY 1,185,004 shares
EACH -------------------------------------------------------------
REPORTING 7. SOLE DISPOSITIVE POWER
PERSON
WITH 0 shares
-------------------------------------------------------------
8. SHARED DISPOSITIVE POWER
1,185,004 shares
- --------------------------------------------------------------------------------
9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,185,004 shares
- --------------------------------------------------------------------------------
10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES* [ ]
- --------------------------------------------------------------------------------
11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
10.0%
- --------------------------------------------------------------------------------
12. TYPE OF REPORTING PERSON*
CO
- --------------------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
Page 9 of 22 Pages
<PAGE> 10
SCHEDULE 13G
Item 1(a). NAME OF ISSUER: ArQule, Inc.
Item 1(b). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
200 Boston Avenue, Medford, Massachusetts 02155.
Item 2(a). NAMES OF PERSONS FILING: Atlas Venture Fund II, L.P., Atlas
Venture Associates II, L.P., Christopher J. Spray, Barry
Fidelman, Allan Ferguson, Jean-Francois Formela, Atlas Venture
Europe Fund B.V. and Atlas InvesteringsGroep N.V.
Atlas Venture Associates II, L.P. is the sole general partner
of Atlas Venture Fund II, L.P. Messrs. Spray, Fidelman,
Ferguson and Formela are the individual general partners of
Atlas Venture Associates II, L.P. Atlas InvesteringsGroep N.V.
is the sole shareholder of Atlas Venture Europe Fund B.V.
Item 2(b). ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE:
The address of the principal business office of Atlas Venture
Fund II, L.P., Atlas Venture Associates II, L.P. and Messrs.
Spray, Fidelman, Ferguson and Formela is Atlas Venture, 222
Berkeley Street, Boston, Massachusetts 02116. The address of
the principal business office of Atlas Venture Europe Fund B.V.
and Atlas InvesteringsGroep N.V. is Atlas InvesteringsGroep
N.V., Naarderpoort 1, 1411 MA Naarden, The Netherlands.
Item 2(c). CITIZENSHIP: Atlas Venture Fund II, L.P. and Atlas Venture
Associates II, L.P. are each a limited partnership organized
under the laws of the State of Delaware. Messrs. Fidelman and
Ferguson are citizens of the United States. Mr. Spray is a
citizen of the United Kingdom. Mr. Formela is a citizen of
France. Atlas Venture Europe Fund B.V. and Atlas
InvesteringsGroep N.V. are each a corporation organized under
the laws of The Netherlands.
Item 2(d). TITLE OF CLASS OF SECURITIES: Common Stock, $.01 par value.
Item 2(e). CUSIP NUMBER: 00004269E1
Item 3. IF THIS STATEMENT IS FILED PURSUANT TO RULES 13d-1(b), OR
13d-2(b), CHECK WHETHER THE PERSON FILING IS A:
(a) [ ] Broker or Dealer registered under Section 15 of the
Securities Exchange Act of 1934 (the "Act").
(b) [ ] Bank as defined in Section 3(a)(6) of the Act.
(c) [ ] Insurance Company as defined in Section 3(a)(19) of
the Act.
(d) [ ] Investment Company registered under Section 8 of
the Investment Company Act of 1940.
Page 10 of 22 Pages
<PAGE> 11
(e) [ ] Investment Adviser registered under Section 203 of
the Investment Advisers Act of 1940.
(f) [ ] Employee Benefit Plan, Pension Fund which is
subject to the provisions of the Employee
Retirement Income Security Act of 1974 or Endowment
Fund; see Rule 13d-1(b)(1)(ii)(F) of the Act.
(g) [ ] Parent Holding Company, in accordance with
Rule 13d-1(b)(ii)(G) of the Act.
(h) [ ] Group, in accordance with Rule 13d-1(b)(1)(ii)(H)
of the Act.
None.
Item 4. OWNERSHIP.
(a) Amount Beneficially Owned:
Each of Atlas Venture Fund II, L.P., Atlas Venture Associates
II, L.P., Atlas Venture Europe Fund B.V. and Atlas
InvesteringsGroep N.V. (individually an "Entity" and
collectively the "Entities") may be deemed to own beneficially
1,185,004 shares of Common Stock as of December 31, 1997. Each
of Messrs. Spray, Fidelman, Ferguson and Formela may be deemed
to own beneficially 670,056 shares of Common Stock as of
December 31, 1997.
As of December 31, 1997, Atlas Venture Fund II, L.P. is the
record owner of 670,056 shares of Common Stock, Atlas
InvesteringsGroep N.V. is the record owner of 127,759 shares of
Common Stock and Atlas Venture Europe Fund B.V. is the record
owner of 387,189 shares of Common Stock (referred to as the
"Record Shares"). By virtue of the affiliate relationships
among the Entities, each Entity may be deemed to own
beneficially all of the Record Shares. Hence, each Entity may
be deemed to own beneficially 1,185,004 shares of Common Stock.
In their capacities as individual general partners of Atlas
Venture Associates II, L.P., each of Messrs. Spray, Fidelman,
Ferguson and Formela may be deemed to own beneficially 670,056
shares of Common Stock.
(b) Percent of Class:
Atlas Venture Fund II, L.P. 10.0%
Atlas Venture Associates II, L.P. 10.0%
Christopher J. Spray 5.6%
Barry Fidelman 5.6%
Allan Ferguson 5.6%
Jean-Francois Formela 5.6%
Atlas Venture Europe Fund B.V. 10.0%
Atlas InvesteringsGroep N.V. 10.0%
Page 11 of 22 Pages
<PAGE> 12
The foregoing percentages are calculated based on the 11,888,909 shares
of Common Stock reported to be outstanding in a Quarterly Report on
Form 10-Q for ArQule, Inc. for the Quarter Ended September 30, 1997.
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote:
0 shares for each reporting person
(ii) shared power to vote or to direct the vote:
Atlas Venture Fund II, L.P. 1,185,004 shares
Atlas Venture Associates II, L.P. 1,185,004 shares
Christopher J. Spray 670,056 shares
Barry Fidelman 670,056 shares
Allan Ferguson 670,056 shares
Jean-Francois Formela 670,056 shares
Atlas Venture Europe Fund B.V. 1,185,004 shares
Atlas InvesteringsGroep N.V. 1,185,004 shares
(iii) sole power to dispose or to direct the dispositions of:
0 shares for each reporting person
(iv) shared power to dispose or to direct the disposition of:
Atlas Venture Fund II, L.P. 1,185,004 shares
Atlas Venture Associates II, L.P. 1,185,004 shares
Christopher J. Spray 670,056 shares
Barry Fidelman 670,056 shares
Allan Ferguson 670,056 shares
Jean-Francois Formela 670,056 shares
Atlas Venture Europe Fund B.V. 1,185,004 shares
Atlas InvesteringsGroep N.V. 1,185,004 shares
Each of the reporting persons expressly disclaims beneficial ownership
of any shares of Common Stock of ArQule, Inc., except in the case of
(i) Atlas Venture Fund II, L.P. for the 670,056 shares which it holds
of record , (ii) Atlas InvesteringsGroep N.V. for the 127,759 shares
which it holds of record, and (iii) Atlas Venture Europe Fund B.V. for
the 387,189 shares which it holds of record.
Item 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.
Not Applicable
Item 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER
PERSON.
Not Applicable.
Page 12 of 22 Pages
<PAGE> 13
Item 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH
ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING
COMPANY.
Not Applicable.
Item 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.
Not Applicable. The reporting persons expressly disclaim
membership in a "group" as defined in Rule 13d-1(b)(ii)(H).
Item 9. NOTICE OF DISSOLUTION OF GROUP.
Not Applicable.
Item 10. CERTIFICATION.
Not Applicable. This statement on Schedule 13G is not filed
pursuant to Rule 13d-1(b).
Page 13 of 22 Pages
<PAGE> 14
SIGNATURES
After reasonable inquiry and to the best of our knowledge and belief,
we certify that the information set forth in this statement is true, complete
and correct. We also hereby agree to file this statement jointly pursuant to the
Agreement listed on EXHIBIT 1 hereto.
Dated: February 6, 1998
ATLAS VENTURE FUND II, L.P. ATLAS INVESTERINGSGROEP N.V.
By: Atlas Venture Associates II, L.P.
By: *
-----------------------------------
Michiel de Haan,
Managing Director
By: *
---------------------------------
Christopher J. Spray,
General Partner *
-----------------------------------
Christopher J. Spray
ATLAS VENTURE ASSOCIATES II, L.P.
*
-----------------------------------
By: * Barry Fidelman
---------------------------------
Christopher J. Spray,
General Partner
*
-----------------------------------
Allan Ferguson
ATLAS VENTURE EUROPE FUND B.V.
By: Atlas InvesteringsGroep N.V. *
-----------------------------------
Jean-Francois Formela
By: *
---------------------------------
Michiel de Haan,
Managing Director
* The undersigned attorney-in-fact, by signing her name below, does hereby
sign this statement on behalf of the above indicated filers pursuant to
Powers of Attorney filed hereto as EXHIBIT 2.
/s/ Jeanne Larkin Henry
---------------------------------
Jeanne Larkin Henry
Attorney-in-fact
Page 14 of 22 Pages
<PAGE> 15
Exhibit 1
---------
AGREEMENT
Pursuant to Rule 13d-1(f)(1) under the Securities Exchange Act of 1934,
the undersigned hereby agree that only one statement containing the information
required by Schedule 13G need be filed with respect to the ownership by each of
the undersigned of shares of Common Stock of ArQule, Inc.
This agreement may be executed in any number of counterparts, each of
which shall be deemed an original.
EXECUTED this 6th day of February, 1998.
ATLAS VENTURE FUND II, L.P. ATLAS INVESTERINGSGROEP N.V.
By: Atlas Venture Associates II, L.P.
By: *
-----------------------------------
Michiel de Haan,
Managing Director
By: *
---------------------------------
Christopher J. Spray,
General Partner *
-----------------------------------
Christopher J. Spray
ATLAS VENTURE ASSOCIATES II, L.P.
*
-----------------------------------
By: * Barry Fidelman
---------------------------------
Christopher J. Spray,
General Partner
*
-----------------------------------
Allan Ferguson
ATLAS VENTURE EUROPE FUND B.V.
By: Atlas InvesteringsGroep N.V. *
-----------------------------------
Jean-Francois Formela
By: *
---------------------------------
Michiel de Haan,
Managing Director
* The undersigned attorney-in-fact, by signing her name below, does hereby
sign this statement on behalf of the above indicated filers pursuant to
Powers of Attorney filed hereto as EXHIBIT 2.
/s/ Jeanne Larkin Henry
---------------------------------
Jeanne Larkin Henry
Attorney-in-fact
Page 15 of 22 Pages
<PAGE> 16
Exhibit 2
---------
POWER OF ATTORNEY
KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears
below hereby constitutes and appoints each and any of Christopher J. Spray and
Jeanne Larkin Henry his true and lawful attorney-in-fact and agent, with full
power of substitution and resubstitution, for him and in his name, place and
stead, in any and all capacities (until revoked in writing) to sign any and all
instruments, certificates and documents required to be executed on behalf of
himself individually or on behalf of each or any of Atlas Venture Fund, L.P.,
Atlas Venture Associates, L.P., Atlas Venture Partners III, B.V., Atlas Venture
Fund II, L.P., Atlas Venture Associates II, L.P., Atlas Venture Europe Fund
B.V., Atlas InvesteringsGroep N.V., and Atlas Venture Beheer II B.V. pursuant to
sections 13 and 16 of the Securities Exchange Act of 1934, as amended (the
"Exchange Act"), and any and all regulations promulgated thereunder, and to file
the same, with all exhibits thereto, and any other documents in connection
therewith, with the Securities and Exchange Commission, and with any other
entity when and if such is mandated by the Exchange Act or by the By-laws of the
National Association of Securities Dealers, granting unto said attorney-in-fact
and agent full power and authority to do and perform each and every act and
thing requisite and necessary fully to all intents and purposes as he might or
could do in person thereby ratifying and confirming all that said
attorney-in-fact and agent, or his substitute or substitutes, may lawfully do or
cause to be done by virtue hereof.
[REMAINDER OF PAGE LEFT BLANK INTENTIONALLY]
[SIGNATURE PAGE FOLLOWS IMMEDIATELY]
Page 16 of 22 Pages
<PAGE> 17
IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 31st
day of January, 1997.
/s/ Christopher J. Spray
-----------------------------------
Christopher J. Spray
Commonwealth of Massachusetts)
) ss:
County of Suffolk )
On this 31st day of January, 1997, before me personally came Christopher
J. Spray, known to me to be the person described and who executed the foregoing
instrument that he acknowledged that he executed the same.
[Notary Seal] /s/ Elizabeth A. LeBlanc
-----------------------------------
Notary Public
My commission expires: July 3, 1998
Page 17 of 22 Pages
<PAGE> 18
IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 31st
day of January, 1997.
/s/ Barry Fidelman
-----------------------------------
Barry Fidelman
Commonwealth of Massachusetts)
) ss:
County of Suffolk )
On this 31st day of January, 1997, before me personally came Barry
Fidelman, known to me to be the person described and who executed the foregoing
instrument that he acknowledged that he executed the same.
[Notary Seal] /s/ Elizabeth A. LeBlanc
-----------------------------------
Notary Public
My commission expires: July 3, 1998
Page 18 of 22 Pages
<PAGE> 19
IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 31st
day of January, 1997.
/s/ Michiel de Haan
-----------------------------------
Michiel de Haan
Commonwealth of Massachusetts)
) ss:
County of Suffolk )
On this 31st day of January, 1997, before me personally came Michiel de
Haan, known to me to be the person described and who executed the foregoing
instrument that he acknowledged that he executed the same.
[Notary Seal] /s/ Elizabeth A. LeBlanc
-----------------------------------
Notary Public
My commission expires: July 3, 1998
Page 19 of 22 Pages
<PAGE> 20
IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 31st
day of January, 1997.
/s/ Evert Smid
-----------------------------------
Evert Smid
Commonwealth of Massachusetts)
) ss:
County of Suffolk )
On this 31st day of January, 1997, before me personally came Evert Smid,
known to me to be the person described and who executed the foregoing instrument
that he acknowledged that he executed the same.
[Notary Seal] /s/ Elizabeth A. LeBlanc
-----------------------------------
Notary Public
My commission expires: July 3, 1998
Page 20 of 22 Pages
<PAGE> 21
IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 31st
day of January, 1997.
/s/ Allan R. Ferguson
-----------------------------------
Allan R. Ferguson
Commonwealth of Massachusetts)
) ss:
County of Suffolk )
On this 31st day of January, 1997, before me personally came Allan R.
Ferguson, known to me to be the person described and who executed the foregoing
instrument that he acknowledged that he executed the same.
[Notary Seal] /s/ Elizabeth A. LeBlanc
-----------------------------------
Notary Public
My commission expires: July 3, 1998
Page 21 of 22 Pages
<PAGE> 22
IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 31st
day of January, 1997.
/s/ Jean-Francois Formela
-----------------------------------
Jean-Francois Formela
Commonwealth of Massachusetts)
) ss:
County of Suffolk )
On this 31st day of January, 1997, before me personally came Jean-Francois
Formela, known to me to be the person described and who executed the foregoing
instrument that he acknowledged that he executed the same.
[Notary Seal] /s/ Elizabeth A. LeBlanc
-----------------------------------
Notary Public
My commission expires: July 3, 1998
Page 22 of 22 Pages
