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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(AMENDMENT NO. 2 )*
----------
ARQULE, INC.
- --------------------------------------------------------------------------------
(Name of Issuer)
COMMON STOCK, $.01 Par Value
- --------------------------------------------------------------------------------
(Title of Class of Securities)
00004269E1
------------------------------------
(CUSIP Number)
- --------------------------------------------------------------------------------
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:
[ ] Rule 13d-1(b)
[ ] Rule 13d-1(c)
[X] Rule 13d-1(d)
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
SEC 1745 (3-98) Page 1 of 22 pages
<PAGE> 2
- -------------------------- --------------------------
CUSIP NO. 00004269E1 13G PAGE 2 OF 22
------------- ----- ------
- -------------------------- --------------------------
- --------------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Atlas Venture Fund II, L.P.
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware Limited Partnership
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
NUMBER OF 0 shares
--------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 1,154,480 shares
--------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 shares
--------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
1,154,480 shares
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,154,480 shares
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
SEE INSTRUCTIONS) [ ]
- --------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
9.5%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
PN
- --------------------------------------------------------------------------------
Page 2 of 22 Pages
<PAGE> 3
- -------------------------- --------------------------
CUSIP NO. 00004269E1 13G PAGE 3 OF 22
------------- ----- ------
- -------------------------- --------------------------
- --------------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Atlas Venture Associates II, L.P.
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware Limited Partnership
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
NUMBER OF 0 shares
--------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 1,154,480 shares
--------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 shares
--------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
1,154,480 shares
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,154,480 shares
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
SEE INSTRUCTIONS) [ ]
- --------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
9.5%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
PN
- --------------------------------------------------------------------------------
Page 3 of 22 Pages
<PAGE> 4
- -------------------------- --------------------------
CUSIP NO. 00004269E1 13G PAGE 4 OF 22
------------- ----- ------
- -------------------------- --------------------------
- --------------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Christopher J. Spray
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
United Kingdom
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
NUMBER OF 0 shares
--------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 664,310 shares
--------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 shares
--------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
664,310 shares
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
664,310 shares
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
SEE INSTRUCTIONS) [ ]
- --------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
5.5%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IN
- --------------------------------------------------------------------------------
Page 4 of 22 Pages
<PAGE> 5
- -------------------------- --------------------------
CUSIP NO. 00004269E1 13G PAGE 5 OF 22
------------- ----- ------
- -------------------------- --------------------------
- --------------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Barry Fidelman
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
NUMBER OF 0 shares
--------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 664,310 shares
--------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 shares
--------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
664,310 shares
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
664,310 shares
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
SEE INSTRUCTIONS) [ ]
- --------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
5.5%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IN
- --------------------------------------------------------------------------------
Page 5 of 22 Pages
<PAGE> 6
- -------------------------- --------------------------
CUSIP NO. 00004269E1 13G PAGE 6 OF 22
------------- ----- ------
- -------------------------- --------------------------
- --------------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Allan Ferguson
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
NUMBER OF 12,0000 shares
--------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 676,310 shares
--------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 12,000 shares
--------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
676,310 shares
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
676,310 shares
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
SEE INSTRUCTIONS) [ ]
- --------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
5.6%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IN
- --------------------------------------------------------------------------------
Page 6 of 22 Pages
<PAGE> 7
- -------------------------- --------------------------
CUSIP NO. 00004269E1 13G PAGE 7 OF 22
------------- ----- ------
- -------------------------- --------------------------
- --------------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Jean-Francois Formela
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
France
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
NUMBER OF 0 shares
--------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 664,310 shares
--------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 shares
--------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
664,310 shares
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
664,310 shares
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
SEE INSTRUCTIONS) [ ]
- --------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
5.5%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IN
- --------------------------------------------------------------------------------
Page 7 of 22 Pages
<PAGE> 8
- -------------------------- --------------------------
CUSIP NO. 00004269E1 13G PAGE 8 OF 22
------------- ----- ------
- -------------------------- --------------------------
- --------------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Atlas Venture Europe Fund B. V.
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
The Netherlands
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
NUMBER OF 0 shares
--------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 1,154,480 shares
--------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 shares
--------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
1,154,480 shares
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,154,480 shares
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
SEE INSTRUCTIONS) [ ]
- --------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
9.5%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
CO
- --------------------------------------------------------------------------------
Page 8 of 22 Pages
<PAGE> 9
- -------------------------- --------------------------
CUSIP NO. 00004269E1 13G PAGE 9 OF 22
------------- ----- ------
- -------------------------- --------------------------
- --------------------------------------------------------------------------------
1 NAMES OF REPORTING PERSONS
I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Atlas InvesteringsGroep N.V.
- --------------------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
(a) [ ]
(b) [ ]
- --------------------------------------------------------------------------------
3 SEC USE ONLY
- --------------------------------------------------------------------------------
4 CITIZENSHIP OR PLACE OF ORGANIZATION
The Neterlands
- --------------------------------------------------------------------------------
5 SOLE VOTING POWER
NUMBER OF 0 shares
--------------------------------------------------
SHARES 6 SHARED VOTING POWER
BENEFICIALLY
OWNED BY 1,154,480 shares
--------------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING
PERSON 0 shares
--------------------------------------------------
WITH: 8 SHARED DISPOSITIVE POWER
1,154,480 shares
- --------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
1,154,480 shares
- --------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
SEE INSTRUCTIONS) [ ]
- --------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
9.5%
- --------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
CO
- --------------------------------------------------------------------------------
Page 9 of 22 Pages
<PAGE> 10
SCHEDULE 13G
Item 1(a). NAME OF ISSUER: ArQule, Inc.
Item 1(b). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
200 Boston Avenue, Medford, Massachusetts 02155.
Item 2(a). NAMES OF PERSONS FILING: Atlas Venture Fund II, L.P., Atlas Venture
Associates II, L.P., Christopher J. Spray, Barry Fidelman, Allan
Ferguson, Jean-Francois Formela, Atlas Venture Europe Fund B.V. and
Atlas InvesteringsGroep N.V.
Atlas Venture Associates II, L.P. is the sole general partner of
Atlas Venture Fund II, L.P. Messrs. Spray, Fidelman, Ferguson and
Formela are the individual general partners of Atlas Venture
Associates II, L.P. Atlas InvesteringsGroep N.V. is the sole
shareholder of Atlas Venture Europe Fund B.V.
Item 2(b). ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE: The
address of the principal business office of Atlas Venture Fund II,
L.P., Atlas Venture Associates II, L.P. and Messrs. Spray, Fidelman,
Ferguson and Formela is Atlas Venture, 222 Berkeley Street, Boston,
Massachusetts 02116. The address of the principal business office of
Atlas Venture Europe Fund B.V. and Atlas InvesteringsGroep N.V. is
Atlas InvesteringsGroep N.V., Naarderpoort 1, 1411 MA Naarden, The
Netherlands.
Item 2(c). CITIZENSHIP: Atlas Venture Fund II, L.P. and Atlas Venture
Associates II, L.P. are each a limited partnership organized under
the laws of the State of Delaware. Messrs. Fidelman and Ferguson are
citizens of the United States. Mr. Spray is a citizen of the United
Kingdom. Mr. Formela is a citizen of France. Atlas Venture Europe
Fund B.V. and Atlas InvesteringsGroep N.V. are each a corporation
organized under the laws of The Netherlands.
Item 2(d). TITLE OF CLASS OF SECURITIES: Common Stock, $.01 par value.
Item 2(e). CUSIP NUMBER: 00004269E1
Item 3. IF THIS STATEMENT IS FILED PURSUANT TO RULES 13D-1(b), OR 13d-2(b)
or (c), CHECK WHETHER THE PERSON FILING IS A:
Not Applicable.
Item 4. OWNERSHIP.
(a) Amount Beneficially Owned:
Each of Atlas Venture Fund II, L.P., Atlas Venture Associates II,
L.P., Atlas Venture Europe Fund B.V. and Atlas InvesteringsGroep
N.V. (individually an "Entity" and collectively the "Entities") may
be deemed to own beneficially 1,154,480 shares of Common Stock as of
December 31, 1998. Each of Messrs. Spray, Fidelman and Formela may
be deemed to own beneficially 664,310
Page 10 of 22 Pages
<PAGE> 11
shares of Common Stock as of December 31, 1998. Mr. Ferguson may be
deemed to own beneficially 676,310 shares (including 12,000 options)
of Common Stock as of December 31, 1998.
As of December 31, 1998, Atlas Venture Fund II, L.P. is the record
owner of 664,310 shares of Common Stock, Atlas InvesteringsGroep
N.V. is the record owner of 114,859 shares of Common Stock and Atlas
Venture Europe Fund B.V. is the record owner of 375,311 shares of
Common Stock (referred to as the "Record Shares"). By virtue of the
affiliate relationships among the Entities, each Entity may be
deemed to own beneficially all of the Record Shares. Hence, each
Entity may be deemed to own beneficially 1,154,480 shares of Common
Stock. In their capacities as individual general partners of Atlas
Venture Associates II, L.P., each of Messrs. Spray, Fidelman and
Formela may be deemed to own beneficially 664,310 shares of Common
Stock. Mr. Ferguson may be deemed to own beneficially 676,310 shares
(including 12,000 options) of Common Stock.
(b) Percent of Class:
Atlas Venture Fund II, L.P. 9.5%
Atlas Venture Associates II, L.P. 9.5%
Christopher J. Spray 5.5%
Barry Fidelman 5.5%
Allan Ferguson 5.6%
Jean-Francois Formela 5.5%
Atlas Venture Europe Fund B.V. 9.5%
Atlas InvesteringsGroep N.V. 9.5%
The foregoing percentages are calculated based on the 12,165,403 shares of
Common Stock reported to be outstanding in a Quarterly Report on Form 10-Q
for ArQule, Inc. for the Quarter Ended September 30, 1998, as adjusted
pursuant to Rule 13d-3(d)(1).
(c) Number of shares as to which such person has:
(i) sole power to vote or to direct the vote:
Allan Ferguson 12,000 shares
0 shares as to each other reporting person
Page 11 of 22 Pages
<PAGE> 12
(ii) shared power to vote or to direct the vote:
Atlas Venture Fund II, L.P. 1,154,480 shares
Atlas Venture Associates II, L.P. 1,154,480 shares
Christopher J. Spray 664,310 shares
Barry Fidelman 664,310 shares
Allan Ferguson 676,310 shares
Jean-Francois Formela 664,310 shares
Atlas Venture Europe Fund B.V. 1,154,480 shares
Atlas InvesteringsGroep N.V. 1,154,480 shares
(iii) sole power to dispose or to direct the disposition of:
Allan Ferguson 12,000 shares
0 shares as to each other reporting person
(iv) shared power to dispose or to direct the disposition of:
Atlas Venture Fund II, L.P. 1,154,480 shares
Atlas Venture Associates II, L.P. 1,154,480 shares
Christopher J. Spray 664,310 shares
Barry Fidelman 664,310 shares
Allan Ferguson 676,310 shares
Jean-Francois Formela 664,310 shares
Atlas Venture Europe Fund B.V. 1,154,480 shares
Atlas InvesteringsGroep N.V. 1,154,480 shares
Each of the reporting persons expressly disclaims beneficial
ownership of any shares of Common Stock of ArQule, Inc., except in
the case of (i) Atlas Venture Fund II, L.P. for the 664,310 shares
which it holds of record, (ii) Allan Ferguson for the 12,000 shares
which he holds of record, (iii) Atlas InvesteringsGroep N.V. for the
114,859 shares which it holds of record, and (iv) Atlas Venture
Europe Fund B.V. for the 375,311 shares which it holds of record.
Item 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.
Not Applicable
Item 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.
Not Applicable.
Item 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE
SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY.
Not Applicable.
Page 12 of 22 Pages
<PAGE> 13
Item 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.
Not Applicable.
The reporting persons expressly disclaim membership in a "group" as
defined in Rule 13d-1(b)(1)(ii)(J).
Item 9. NOTICE OF DISSOLUTION OF GROUP.
Not Applicable.
Item 10. CERTIFICATIONS.
Not Applicable. This statement on Schedule 13G is not filed pursuant
to Rule 13d-1(b) or Rule 13d-1(c).
Page 13 of 22 Pages
<PAGE> 14
SIGNATURES
After reasonable inquiry and to the best of our knowledge and belief, we
certify that the information set forth in this statement is true, complete and
correct. We also hereby agree to file this statement jointly pursuant to the
Agreement listed on EXHIBIT 1 hereto.
Dated: February 10, 1999
ATLAS VENTURE FUND II, L.P. ATLAS INVESTERINGSGROEP N.V.
By: Atlas Venture Associates II, L.P.
By: *
---------------------------
Michiel de Haan,
Managing Director
By: *
---------------------------
Christopher J. Spray,
General Partner *
---------------------------
Christopher J. Spray
ATLAS VENTURE ASSOCIATES II, L.P.
*
---------------------------
By: * Barry Fidelman
---------------------------
Christopher J. Spray,
General Partner
*
---------------------------
Allan Ferguson
ATLAS VENTURE EUROPE FUND B.V.
By: Atlas InvesteringsGroep N.V. *
---------------------------
Jean-Francois Formela
By: *
---------------------------
Michiel de Haan,
Managing Director
* The undersigned attorney-in-fact, by signing her name below, does hereby
sign this statement on behalf of the above indicated filers pursuant to
Powers of Attorney filed hereto as EXHIBIT 2.
/s/ Jeanne Larkin Henry
---------------------------
Jeanne Larkin Henry
Attorney-in-fact
Page 14 of 22 Pages
<PAGE> 1
EXHIBIT 1
AGREEMENT
Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the
undersigned hereby agree that only one statement containing the information
required by Schedule 13G need be filed with respect to the ownership by each of
the undersigned of shares of Common Stock of ArQule, Inc.
This agreement may be executed in any number of counterparts, each of which
shall be deemed an original.
EXECUTED this 10th day of February, 1999.
ATLAS VENTURE FUND II, L.P. ATLAS INVESTERINGSGROEP N.V.
By: Atlas Venture Associates II, L.P.
By: *
----------------------------
Michiel de Haan,
Managing Director
By: *
---------------------------------
Christopher J. Spray,
General Partner *
----------------------------
Christopher J. Spray
ATLAS VENTURE ASSOCIATES II, L.P.
*
----------------------------
By: * Barry Fidelman
---------------------------------
Christopher J. Spray,
General Partner
*
----------------------------
Allan Ferguson
ATLAS VENTURE EUROPE FUND B.V.
By: Atlas InvesteringsGroep N.V. *
----------------------------
Jean-Francois Formela
By: *
---------------------------------
Michiel de Haan,
Managing Director
* The undersigned attorney-in-fact, by signing her name below, does hereby
sign this statement on behalf of the above indicated filers pursuant to
Powers of Attorney filed hereto as EXHIBIT 2.
/s/ Jeanne Larkin Henry
-------------------------------
Jeanne Larkin Henry
Attorney-in-fact
Page 15 of 22 Pages
<PAGE> 1
EXHIBIT 2
POWER OF ATTORNEY
KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears
below hereby constitutes and appoints each and any of Christopher J. Spray and
Jeanne Larkin Henry his true and lawful attorney-in-fact and agent, with full
power of substitution and resubstitution, for him and in his name, place and
stead, in any and all capacities (until revoked in writing) to sign any and all
instruments, certificates and documents required to be executed on behalf of
himself individually or on behalf of each or any of Atlas Venture Fund, L.P.,
Atlas Venture Associates, L.P., Atlas Venture Partners III, B.V., Atlas Venture
Fund II, L.P., Atlas Venture Associates II, L.P., Atlas Venture Europe Fund
B.V., Atlas InvesteringsGroep N.V., and Atlas Venture Beheer II B.V. pursuant to
sections 13 and 16 of the Securities Exchange Act of 1934, as amended (the
"Exchange Act"), and any and all regulations promulgated thereunder, and to file
the same, with all exhibits thereto, and any other documents in connection
therewith, with the Securities and Exchange Commission, and with any other
entity when and if such is mandated by the Exchange Act or by the By-laws of the
National Association of Securities Dealers, granting unto said attorney-in-fact
and agent full power and authority to do and perform each and every act and
thing requisite and necessary fully to all intents and purposes as he might or
could do in person thereby ratifying and confirming all that said
attorney-in-fact and agent, or his substitute or substitutes, may lawfully do or
cause to be done by virtue hereof.
[REMAINDER OF PAGE LEFT BLANK INTENTIONALLY]
[SIGNATURE PAGE FOLLOWS IMMEDIATELY]
Page 16 of 22 Pages
<PAGE> 2
IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 31st
day of January, 1997.
/s/ Christopher J. Spray
------------------------------------
Christopher J. Spray
Commonwealth of Massachusetts)
) ss:
County of Suffolk )
On this 31st day of January, 1997, before me personally came Christopher J.
Spray, known to me to be the person described and who executed the foregoing
instrument that he acknowledged that he executed the same.
[Notary Seal] /s/ Elizabeth A. Leblanc
------------------------------------
Notary Public
My commission expires: July 3, 1998
Page 17 of 22 Pages
<PAGE> 3
IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 31st
day of January, 1997.
/s/ Barry Fidelman
-----------------------------------
Barry Fidelman
Commonwealth of Massachusetts)
) ss:
County of Suffolk )
On this 31st day of January, 1997, before me personally came Barry
Fidelman, known to me to be the person described and who executed the foregoing
instrument that he acknowledged that he executed the same.
[Notary Seal] /s/ Elizabeth A. Leblanc
------------------------------------
Notary Public
My commission expires: July 3, 1998
Page 18 of 22 Pages
<PAGE> 4
IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 31st
day of January, 1997.
/s/ Michiel de Haan
---------------------------------
Michiel de Haan
Commonwealth of Massachusetts)
) ss:
County of Suffolk )
On this 31st day of January, 1997, before me personally came Michiel de
Haan, known to me to be the person described and who executed the foregoing
instrument that he acknowledged that he executed the same.
[Notary Seal] /s/ Elizabeth A. Leblanc
---------------------------------
Notary Public
My commission expires: July 3, 1998
Page 19 of 22 Pages
<PAGE> 5
IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 31st
day of January, 1997.
/s/ Allan R. Ferguson
----------------------------------
Allan R. Ferguson
Commonwealth of Massachusetts)
) ss:
County of Suffolk )
On this 31st day of January, 1997, before me personally came Allan R.
Ferguson, known to me to be the person described and who executed the foregoing
instrument that he acknowledged that he executed the same.
[Notary Seal] /s/ Elizabeth A. Leblanc
----------------------------------
Notary Public
My commission expires: July 3, 1998
Page 21 of 22 Pages
<PAGE> 6
IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 31st
day of January, 1997.
/s/ Jean-Francois Formela
----------------------------------
Jean-Francois Formela
Commonwealth of Massachusetts)
) ss:
County of Suffolk )
On this 31st day of January, 1997, before me personally came Jean-Francois
Formela, known to me to be the person described and who executed the foregoing
instrument that he acknowledged that he executed the same.
[Notary Seal] /s/ Elizabeth A. Leblanc
----------------------------------
Notary Public
My commission expires: July 3, 1998
