ARQULE INC
10-Q, EX-11.1, 2000-08-04
PHARMACEUTICAL PREPARATIONS
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<PAGE>   1
                                  ARQULE, INC.

                                                                    EXHIBIT 11.1

                                  ArQule, Inc.
            Statement Re Computation of Unaudited Net Loss Per Share
                      (In thousands, except per share data)

<TABLE>
<CAPTION>
                                                  Three Months Ended June 30,         Six Months Ended June 30,
                                                            (Unaudited)                     (Unaudited)
                                                   --------------------------         -------------------------
                                                     2000              1999              2000          1999
                                                   -------            -------          -------        -------
<S>                                                <C>                <C>              <C>             <C>
Net income / (loss)                                $   609            $(3,594)         $  (733)        (7,560)
                                                   =======            =======          =======        =======
Weighted average shares outstanding:
   Common Stock                                     13,520             12,560           13,362         12,438

Weighted average common shares outstanding          13,520             12,560           13,362         12,438
                                                   =======            =======          =======        =======
   Basic net income / (loss) per share             $  0.05            $ (0.29)         $ (0.05)       $ (0.61)
                                                   =======            =======          =======        =======

</TABLE>

<TABLE>
<CAPTION>

                                                  Three Months Ended June 30,        Six Months Ended June 30,
                                                            (Unaudited)                      (Unaudited)
                                                   ---------------------------        -------------------------
                                                    2000                1999             2000           1999
                                                   -------            --------         --------       --------
<S>                                                <C>                <C>              <C>            <C>
Net income / (loss)                                $   609            $(3,594)         $  (733)       $ (7,560)
                                                   =======            =======          =======        ========
Weighted average shares outstanding:
   Common Stock                                     13,520             12,560           13,362          12,438
   Stock option common stock equivalents               878                 --               --              --
                                                   -------            -------          -------        --------
Weighted average common shares and equivalents
  outstanding                                       14,398             12,560           13,362          12,438
                                                   =======            =======          =======        ========
   Diluted net income / (loss) per share           $  0.04            $ (0.29)         $ (0.05)       $  (0.61)
                                                   =======            =======          =======        ========
</TABLE>

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