UPJOHN CO
10-Q, 1995-08-11
PHARMACEUTICAL PREPARATIONS
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                                FORM 10-Q

                     SECURITIES AND EXCHANGE COMMISSION
                          Washington, D.C.  20549

          [X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d)
                  OF THE SECURITIES EXCHANGE ACT OF 1934

               For the Quarterly Period Ended June 30, 1995

                                    OR

          [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d)
                  OF THE SECURITIES EXCHANGE ACT OF 1934

          For the Transition Period From           to          

         _______________________________________________________


                    Commission File Number 1-4147



                           THE UPJOHN COMPANY             
         (Exact name of registrant as specified in its charter)


                    Delaware                  38-1123360  
            (State of incorporation)      (I. R. S. Employer
                                          Identification No.)


              7000 Portage Road, Kalamazoo, Michigan  49001
                 (Address of principal executive offices)


                Registrant's telephone number 616-323-4000


Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange
Act of 1934 during the preceding twelve months, and (2) has been subject
to such filing requirements for the past 90 days.  YES   X      NO      


The number of shares of Common Stock, $1 Par Value, outstanding as of
August 8, 1995


                           was 171,198,305.


                          Page 1 of 17 pages
             The exhibit index is set forth on page 13.

<PAGE>
PART I - FINANCIAL INFORMATION
Item 1.  Financial Statements
<TABLE>
                            THE UPJOHN COMPANY AND SUBSIDIARIES
                            CONSOLIDATED STATEMENTS OF EARNINGS
                 (All Dollar Amounts in Thousands, Except Per-Share Data)
<CAPTION>

                                                           Unaudited                   
                                          ----------------------------------------------
                                           For Three Months          For Six Months
                                             Ended June 30,          Ended June 30,    
                                          -------------------    -----------------------
                                            1995       1994         1995         1994 
                                          --------   --------    ----------   ----------
<S>                                       <C>        <C>         <C>          <C>
Net sales                                 $834,729   $818,654    $1,643,446   $1,619,350
Other revenue                               16,104     14,236        74,123       24,507
                                          --------   --------    ----------   ----------
    Operating revenue                      850,833    832,890     1,717,569    1,643,857
    
Cost of products sold                      221,542    217,790       446,828      420,558
Research & development                     146,761    148,310       290,809      303,091
Marketing & administrative                 330,376    316,529       628,153      617,982
                                          --------   --------    ----------   ----------
    Operating income                       152,154    150,261       351,779      302,226

Interest income                             20,885     14,098        40,690       27,356
Interest expense                            (7,045)    (6,253)      (12,988)     (12,671)
Foreign exchange losses                     (1,439)      (350)       (1,147)      (2,079)
All other, net                              (1,295)    (2,687)       (1,557)        (374)
                                          --------   --------    ----------   ----------
Earnings from continuing operations 
 before income taxes                       163,260    155,069       376,777      314,458
Provision for income taxes                  47,400     37,000       109,300       72,500
                                          --------   --------    ----------   ----------
Earnings from continuing operations        115,860    118,069       267,477      241,958
Earnings from discontinued operation
 (net of tax)                                           2,016                     12,880
                                          --------   --------    ----------   ----------
Net earnings                               115,860    120,085       267,477      254,838
Dividends on preferred stock 
 (net of tax)                                3,118      3,089         6,186        6,126
                                          --------   --------    ----------   ----------
Net earnings on common stock              $112,742   $116,996    $  261,291   $  248,712
                                          ========   ========    ==========   ==========
Earnings per common share:
 Primary  - Earnings from continuing
            operations                        $.66       $.66         $1.51        $1.36
          - Discontinued operation                        .01                        .07
                                              ----       ----         -----        -----
          - Net earnings                      $.66       $.67         $1.51        $1.43
                                              ====       ====         =====        =====
 Fully    - Earnings from continuing 
 Diluted    operations                        $.63       $.64         $1.46        $1.32
          - Discontinued operation                        .01                        .07
                                              ----       ----         -----        -----
          - Net earnings                      $.63       $.65         $1.46        $1.39
                                              ====       ====         =====        =====

</TABLE>


                                  See accompanying notes.
<PAGE>

                      THE UPJOHN COMPANY AND SUBSIDIARIES
                CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

                       For the Six Months Ended June 30
                       (All Dollar Amounts in Thousands)


                                                             Unaudited
                                                         1995         1994  
                                                       --------     --------
Net cash provided by operations                        $252,639     $311,471
                                                       --------     --------
Cash provided (required) by investment activities:
  Property, plant and equipment additions               (96,651)    (113,920)
  Proceeds from sale of property, plant and equipment     5,230       25,479
  Proceeds from sale of investments                     158,888       78,304
  Purchase of investments                              (293,870)    (189,850)
  Proceeds from sale of discontinued operation                         7,943
  Other                                                   6,038       (5,476)
                                                       --------     --------
Net cash required by investment activities             (220,365)    (197,520)
                                                       --------     --------
Cash provided (required) by financing activities:
  Proceeds from issuance of debt                         11,693        6,367
  Repayment of debt                                     (13,447)     (13,566)
  Debt maturing in three months or less                 (21,669)       3,814
  Dividends paid to shareholders                       (131,855)    (131,839)
  Purchase of treasury stock                           (102,599)     (23,021)
  Other                                                  12,546        1,582
                                                       --------     --------
Net cash required by financing activities              (245,331)    (156,663)
                                                       --------     --------
Effect of exchange rate changes on cash                  14,625        2,167
                                                       --------     --------
Net change in cash and cash equivalents                (198,432)     (40,545)
Cash and cash equivalents, beginning of year            502,346      291,750
                                                       --------     --------
Cash and cash equivalents, end of period               $303,914     $251,205
                                                       ========     ========


                            See accompanying notes.
<PAGE>


                      THE UPJOHN COMPANY AND SUBSIDIARIES
                          CONSOLIDATED BALANCE SHEETS

                       (All Dollar Amounts in Thousands)


                                                      June 30,   December 31,
                                                        1995         1994    
                                                    -----------  ------------
                                                    (unaudited)

                    ASSETS
Current assets:
  Cash and cash equivalents                         $  303,914   $  502,346
  Trade accounts receivable, less allowances 
     of $35,538 and $36,088                            671,767      650,522
  Inventories                                          502,172      458,676
  Deferred income taxes                                157,397      151,783
  Other                                                506,630      367,111
                                                    ----------   ----------
          Total current assets                       2,141,880    2,130,438
                                                    ----------   ----------
Investments, at cost                                   598,254      647,092
                                                    ----------   ----------
Property, plant and equipment, at cost               3,203,532    3,079,537
Less:  Allowance for depreciation                   (1,351,189)  (1,280,866)
                                                    ----------   ----------
         Net property, plant and equipment           1,852,343    1,798,671
                                                    ----------   ----------
Other noncurrent assets                                651,109      586,260
                                                    ----------   ----------
Total assets                                        $5,243,586   $5,162,461
                                                    ==========   ==========



                            See accompanying notes.

<PAGE>
                      THE UPJOHN COMPANY AND SUBSIDIARIES
                          CONSOLIDATED BALANCE SHEETS

                       (All Dollar Amounts in Thousands)

                                                     June 30,    December 31,
                                                       1995          1994
                                                    -----------  ------------
                                                    (unaudited)

      LIABILITIES AND SHAREHOLDERS' EQUITY
Current liabilities:
  Short-term debt, including current 
    maturities of long-term debt                    $   60,285   $   42,090
  Accounts payable                                     131,703      179,802
  Compensation and vacation                            102,016      110,699
  Dividends payable                                     63,400       64,060
  Income taxes payable                                 226,702      189,015
  Other                                                494,967      533,274
                                                    ----------   ----------
          Total current liabilities                  1,079,073    1,118,940
                                                    ----------   ----------
Long-term debt                                         515,005      520,977
                                                    ----------   ----------
Guarantee of ESOP debt                                 267,200      274,800
                                                    ----------   ----------
Postretirement benefit cost                            374,607      369,217
                                                    ----------   ----------
Other noncurrent liabilities                           403,443      396,671
                                                    ----------   ----------  
Deferred income taxes                                  101,879       99,238
                                                    ----------   ----------
Shareholders' equity:
  Preferred stock, one dollar par value; 
    authorized 12,000,000 shares; issued 
    Series B convertible 7,263 shares 
    (1994: 7,322 shares) at stated value               292,719      295,079
  Common stock, one dollar par value; authorized
     600,000,000 shares, issued 190,589,607 shares     190,590      190,590
  Capital in excess of par value                        62,828       64,636
  Retained earnings                                  2,891,048    2,757,260
  Note receivable from ESOP Trust (ESOT)               (33,520)     (33,520)
  ESOP deferred compensation                          (239,910)    (243,962)
  Currency translation adjustments                      34,463      (33,057)
  Less treasury stock at cost 17,655,515 shares     
     (1994: 17,447,880 shares)                        (695,839)    (614,408)
                                                    ----------   ----------
          Total shareholders' equity                 2,502,379    2,382,618
                                                    ----------   ----------
Total liabilities and shareholders' equity          $5,243,586   $5,162,461
                                                    ==========   ==========


                         See accompanying notes.

<PAGE>
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS - UNAUDITED
(All Dollar Amounts in Thousands, Except Per-Share Data):

A - INTERIM CONSOLIDATED FINANCIAL STATEMENTS:

The consolidated financial information presented herein is unaudited, other
than the consolidated balance sheet at December 31, 1994, which is derived
from audited financial statements.  The interim financial statements and notes
thereto do not include all disclosures required by generally accepted
accounting principles and should be read in conjunction with the financial
statements and notes thereto included in the company's latest annual report on
Form 10-K.

In the opinion of management, the interim financial statements reflect all
adjustments of a normal recurring nature necessary for a fair statement of the
results for interim periods.  The current period's results of operations are
not necessarily indicative of results that ultimately may be achieved for the
year.

In December 1994, the company sold its interests in the Asgrow Seed Company. 
Where appropriate, these financial statements have been restated to reflect
this sale as a discontinued operation.

B - EARNINGS PER COMMON SHARE:

Earnings per share are computed by dividing net earnings available to the
common shareholder by the sum of the weighted average number of shares of
common stock outstanding plus common stock equivalents principally in the form
of employee stock option awards and, in the case of fully diluted earnings per
share, the number of common shares into which the preferred stock would be
assumed to be converted.  Also in the fully diluted computation, net earnings
are adjusted by the difference between dividends on preferred and common stock
under the if-converted assumption.  

C - INVENTORIES:
                                                    June 30,     December 31,
                                                      1995           1994
                                                    --------     ------------
   Estimated replacement cost
     (FIFO basis):
   Pharmaceutical finished products                 $226,570       $216,165
   Raw materials, supplies and work in process       420,344        382,501
                                                    --------       --------
                                                     646,914        598,666
   Less reduction to LIFO cost                      (144,742)      (139,990)
                                                    --------       --------
                                                    $502,172       $458,676
                                                    ========       ========

Inventories valued on the LIFO method had an estimated replacement cost (FIFO
basis) of $375,873 at June 30, 1995, and $360,124 at December 31, 1994.

D - DEBT:

Long-term debt consisted of the following:                                    
                                                    June 30,     December 31,
                                                      1995           1994
                                                    --------     ------------
   7.5% Industrial Revenue Bonds due 2023           $ 40,000       $ 40,000
   5.35-7.95% Medium-Term Notes due 1997-1999        266,000        266,000
   5.875% Notes due 2000                             200,000        200,000
   Other                                              13,207         18,103
   Current maturities                                 (4,202)        (3,126)
                                                    --------       --------
                                                    $515,005       $520,977
                                                    ========       ========

The Medium-Term Notes were issued under 1993 and 1991 shelf registrations
filed with the Securities and Exchange Commission.  At June 30, 1995, $134,000
remained available for issuance under these registrations.

E - CONTINGENT LIABILITIES:

The consolidated balance sheets include accruals for estimated product and
environmental liabilities.  The latter includes exposures related to
discontinued operations, including the industrial chemical facility at North
Haven, Connecticut, and environmental exposures at several "Superfund" or
comparable sites.  

The company has committed to make a series of investments, as certain progress
goals are met, in a company that intends to manufacture a hemoglobin-based
oxygen carrier.  These investments could aggregate $179,000 over a period of
years.  As of June 30, 1995, the company has invested $96,000.  Also pursuant
to the agreement, the company has committed to conduct clinical development.

F - LITIGATION:

There are various legal proceedings against the company, including a
substantial number of product liability suits claiming damages as a result of
the use of the company's products including approximately 100 cases involving
HALCION, and over 100 lawsuits in Australia involving DEPO-MEDROL.

The company is involved in several administrative and judicial proceedings
relating to environmental matters, including actions brought by the U.S. EPA
and state environmental agencies for cleanup at approximately 40 "Superfund"
or comparable sites.  The company's estimate of the ultimate cost to be
incurred in connection with these environmental situations could change due to
cleanup procedures to be employed, if any; the cost of cleanup; and the
company's share of a site's cost.    

Upjohn has been named, along with at least 30 other defendants (both
manufacturers and wholesalers), in a number of federal civil antitrust
lawsuits some of which have been or are in the process of being consolidated
and transferred to the Federal District Court for the Northern District of
Illinois for purposes of discovery.  These suits, brought by retail pharmacies
and chains, generally allege unlawful conspiracy, price discrimination and
price fixing and, in some cases, unfair competition, and specifically allege
that Upjohn and the other named defendants violated:  (1) the Robinson Patman
Act by giving substantial discounts to hospitals, nursing homes, mail-order
pharmacies, and HMOs without according the same discounts to retail
drugstores, and (2) Section 1 of the Sherman Antitrust Act by entering into
illegal vertical combinations with other manufacturers and wholesalers to
restrict certain discounts and rebates so they benefited only favored
customers.  The Federal District Court for the Northern District of Illinois
has certified a class consisting of retail pharmacies, and the same court has
pending before it a suit with approximately 2,500 named retail pharmacies. 
The suits seek treble damages and an injunction prohibiting the alleged
illegal practices.  In addition, similar actions have been brought in Alabama,
California, Colorado, Minnesota, New York, Washington, and Wisconsin state
courts.  The California State court has recently certified a class of
consumers seeking damages resulting from the same alleged conspiracy by the
defendant pharmaceutical companies.

Based on information currently available and the company's experience with
lawsuits of the nature of those currently filed or anticipated to be filed
which have resulted from business activities to date, the amounts accrued for
product and environmental liabilities arising from the litigation and
proceedings referred to above are considered to be adequate.  Although the
company cannot predict the outcome of individual lawsuits, at this time the
company believes the ultimate liability should not have a material effect on
consolidated financial position; and unless there is a significant deviation
from the historical pattern of resolution of such issues, the ultimate
liability should not have a material adverse effect on the company's results
of operations or liquidity.

For several years, the company has been in the process of evaluating existing
environmental conditions at the North Haven, Connecticut facility.  This
evaluation, conducted in compliance with a corrective action order issued by
the U.S. EPA on September 29, 1989, is largely complete.  The U.S. EPA and the
company have entered into an Administrative Order on Consent (effective as of
June 18, 1994) under which the company will conduct a Corrective Measures
Study and will implement interim measures appropriate for site stabilization
pending final remedial work as may be necessary.

G - DERIVATIVE FINANCIAL INSTRUMENTS:

The company utilizes derivative financial instruments in conjunction with its
foreign currency risk management programs and does not use such instruments
for trading purposes.  These programs include the creation of designated
hedges of the net foreign currency transaction exposures of certain
significant international subsidiary operations.  There were no hedges of
anticipated transactions at June 30, 1995.

The company's program to hedge net foreign currency transaction exposures is
designed to protect operating results and cash flows from potential adverse
effects of foreign currency fluctuations related to intercompany and selected
third-party transactions.  The hedging activities seek to limit this risk by
offsetting the gains and losses on the underlying exposures with losses and
gains on the instruments utilized to create the hedge.  This program utilizes
over-the-counter forward exchange contracts with terms consistent with the
underlying exposures.  These contracts generally have maturities that do not
exceed twelve months and require the company to exchange currencies at agreed-
upon rates at maturity.

At June 30, 1995, the notional amount of the company's outstanding foreign
exchange forward contracts held related to the net transaction exposure
hedging program was $151,332.  

The counterparties to these contracts consist of a limited number of major
international financial institutions.  The company does not expect any losses
from credit exposure due to review and control procedures established by
corporate policy.

H - RESTRUCTURING:

The company accrued restructuring charges as of September 30, 1993, that
included costs of $136,109 related to a worldwide work-force reduction of
approximately 1,500 employees.  The majority of these employees were employed
in marketing, administrative, and manufacturing functions.  As of June 30,
1995, approximately 1,300 employees had terminated under this restructuring
program.  Of the amount originally accrued for work-force reduction,
approximately $8,600 remains as current and noncurrent liabilities of the
company.  There have been no adjustments made to increase or decrease the
liabilities originally accrued for the purpose of work-force reduction.

Item 2.  Management's Discussion and Analysis of Financial Condition and
Results of Operations:

RESULTS OF OPERATIONS


                                (Dollars in Millions, except per share)
                            -----------------------------------------------
                               Second Quarter             Six Months
                            --------------------    -----------------------
                                  Percent                    Percent
                            1995  Change   1994      1995    Change    1994
                            ----  -------  ----      ----    -------   ----

Total revenue              $850.8    2%   $832.9   $1,717.6     4%   $1,643.9
Operating income            152.2    1     150.3      351.8    16       302.2
Earnings from continuing
  operations before income
  taxes                     163.3    5     155.1      376.8    20       314.5
Earnings from continuing
  operations                115.9   (2)    118.1      267.5    11       242.0
Net earnings                115.9   (4)    120.1      267.5     5       254.8
Earnings per common share
  from continuing 
  operations:
  - Primary                  $.66    -      $.66      $1.51    11       $1.36
  - Fully diluted            $.63   (1)     $.64      $1.46    11       $1.32

All sales data and financial results for the second quarter and six months of
1994 have been restated to reflect the sale of the Asgrow Seed Company as a
discontinued operation.  

Second-quarter 1995 international sales were up 18 percent to $422 million
from $357 million in the second quarter of 1994.  International sales
represented 51 percent of the consolidated total as compared to 44 percent one
year earlier.  Domestic sales of $413 million declined 11 percent from $462
million for the same comparative period.  Total consolidated sales for the
second quarter were $835 million, up from $819 million in the second quarter
of 1994 as the result of a three percent increase in price, a four percent
increase from foreign exchange, offset by a five percent decline in volume. 
For the six months ended June 30, 1995, international sales of $822 million
were up 21 percent from $678 million while domestic sales of $821 million were
down 13 percent from $941 million.  International sales represented slightly
over 50% of the consolidated total for the 1995 year-to-date period.  

Total revenue for the first six months of 1995 benefited from the first
quarter sale of the company's rights under a product co-marketing agreement. 
This sale added $26 million (15 cents per share) to net earnings for the six
months ended June 30, 1995.  This agreement increased earnings per share by 2
cents and 3 cents, respectively, in the second quarter and first six months of
1994.

An increase in the effective tax rate reduced primary earnings per share by 5
cents and 13 cents for the second quarter and first six months of 1995,
respectively.  Also affecting year-to-year comparisons, the discontinued
Asgrow Seed Company contributed $2 million (1 cent per share) and $13 million
(7 cents per share) to net earnings in the second quarter and first six months
of 1994, respectively.  

The table below provides a year-to-year comparison of consolidated net sales
by major pharmaceutical product group:

                                         (Dollars in Millions)
                            -------------------------------------------------
                               Second Quarter               Six Months
                            --------------------    -------------------------
                                  Percent                    Percent
                            1995  Change   1994      1995    Change     1994
                            ----  -------  ----      ----    -------    ----

Central nervous system     $110.5   (2)   $112.4   $  214.7    (5)   $  225.2
Steroids, anti-
inflammatory and 
  analgesic                  90.2  (15)    106.7      174.1   (16)      208.1
Reproductive and women's
  health                    141.7   13     125.5      267.2     9       244.7
Critical care, transplant
  and cancer                116.3   12     104.1      232.4    17       198.1
Infectious disease          121.5   16     104.3      260.2    21       215.7
Animal health                87.6   16      75.8      171.4    12       153.5
Other products and 
  materials                 166.9  (12)    189.9      323.4   (14)      374.1
                           ------         ------   --------          --------
Consolidated net sales     $834.7    2    $818.7   $1,643.4     1    $1,619.4
                           ======         ======   ========          ========

PRODUCT SALES

The second quarter 1995 worldwide decline in sales of central nervous system
agents was the net result of continuing international sales growth recorded
for both XANAX/alprazolam, the anti-anxiety agent, and HALCION/triazolam, the
sleep inducing agent, being offset by ongoing generic competition against
XANAX in the U.S.  The second quarter 1995 U.S. sales decline in XANAX was
significantly less in both dollars and as a percent of prior year sales than
that experienced during either the second quarter of 1994 or the first quarter
of 1995.

A significant decline in the U.S. sales of ANSAID (flurbiprofen), resulting
from generic competition first encountered in late 1994, led to the overall
decline in the steroid, anti-inflammatory and analgesic product group for both
the second quarter and first six months of 1995.  MOTRIN IB, the over-the-
counter nonsteroidal analgesic agent, also recorded significant sales declines
for both measurement periods in 1995.  These declines have been attributed to
trade efforts to reduce inventories and to intense competition resulting from
increased promotional activity within this market segment.  Strong sales
increases of specialty and commodity steroids in Europe mitigated the decline
in this product group for the quarter.

Good U.S. sales performance in the second quarter of 1995 by DEPO-PROVERA, the
injectable contraceptive, continued to lead the growth in the reproductive and
women's health products group.  A U.S. Food and Drug Administration moratorium
protecting the exclusivity of DEPO-PROVERA expires in October 1995.  This
sales growth was partially offset by the continuing decline in the sales of
OGEN, the estrogen replacement therapy, that has been subject to generic
substitution.   

The sales increases in the critical care, transplant and cancer products group
was led by foreign sales of SOLU-MEDROL, the injectable steroid, and other
MEDROL products.  Strong international sales growth in the DALACIN (CLEOCIN in
the U.S.) family of antibiotic products led the growth in the infectious
disease products category while sales of VANTIN, the broad-spectrum oral
antibiotic, were down slightly in the U.S.

The second quarter increase in sales of animal health products was led by
Lincomycin and Spectinomycin antibiotic products in international markets. 
International sales also benefitted from the performance of the antibiotic
EXCENEL (NAXCEL in U.S. markets).  U.S. sales of NAXCEL increased primarily as
the result of a favorable comparison to the prior year second quarter.
 
Continuing generic competition for MICRONASE Tablets (glyburide), the oral
anti-diabetes agent that lost U.S. market exclusivity in the second quarter of
1994, resulted in the decline in sales of other products and materials for
both the quarter and first six months of 1995.  GLYNASE PresTab, the oral
anti-diabetes agent, continued to record good growth.  U.S. FDA moratoriums on
the approval of Abbreviated New Drug Applications protecting the exclusivity
for GLYNASE expired at the end of March 1995.

COSTS AND EXPENSES

Consolidated operating expenses, stated as a percent of sales, were as
follows:

                                          Second Quarter     Six Months
                                          --------------    -------------
                                          1995      1994    1995     1994
                                          ----      ----    ----     ----
Cost of products sold                     26.5%     26.6%   27.2%    26.0%
Research and development                  17.6      18.1    17.7     18.7
Marketing and administrative              39.6      38.7    38.2     38.2
Operating income                          18.2      18.4    21.4     18.7

Cost of products sold as a percent of sales was slightly below prior-year
levels for the quarter but was up for the year-to-date period as the result of
a change in product and geographic mix.  These rates are higher than in prior
years because the company's generic and other products carry lower gross
margins than the products that have recently lost patent protection.  Also, as
noted above, a higher percentage of total sales were realized in international
markets.  The company's product line generally carries lower gross margins in
international markets.  

Expenditures for research and development were down somewhat both in dollars
and as a percent of sales for the second quarter and first six months of 1995. 
This is the result of a favorable comparison due to the timing of certain
expenditures related to major clinical trials.  It is expected that, in
dollars, research and development expenditures for the current year will
approximate those incurred for the full year 1994.

The increase in marketing and administrative expense, as a percent of second
quarter sales, is primarily the result of additional marketing investments 
required in the emerging international markets of Central Europe, Latin
American, and the Asian and Pacific region.  This increase offset the
significant dollar savings realized in the U.S. from expense controls and from
the 1993 restructuring.  For the year-to-date, this measure was flat as a
percent of sales because first quarter savings in the U.S. had exceeded the
expense growth in international markets.

The increase in operating income as a percent of sales for the current year-
to-date is the direct result of the revenue realized from the sale of rights
under the product co-marketing agreement discussed above.  Excluding revenue
and direct expense related to this agreement, operating income would have been
18.8 percent of sales, up from 18.2 percent for the prior year-to-date period.

NONOPERATING INCOME AND EXPENSE

Net interest income increased in 1995 due largely to investment of the
proceeds from the sale of the discontinued Asgrow Seed Company.  Second
quarter and six months 1994 minority equity in earnings (losses) of $1.9
million and ($.2) million, respectively, have been reclassified to "All other,
net" for consistency with the current year presentation.  These measures for
the equivalent periods in 1995 were immaterial.

INCOME TAXES

The estimated annual effective tax rate for 1995 is 29 percent, compared to 24
percent in 1994 (the effective rate for the first six months of 1994 was 23
percent after the restatement to reflect the exclusion of Asgrow Seed
Company).  The higher rate for 1995 resulted from changes in the U.S. tax law,
which significantly reduced tax benefits from operations in Puerto Rico.

FINANCIAL CONDITION

The following ratios are presented as indicators of financial condition and
performance:

                                               June 30,     December 31,
                                                 1995           1994
                                               --------     ------------

Working capital (in millions)                  $1,063          $1,011
Current ratio                                    1.98            1.90
Debt to total capitalization                    25.2%           26.0%
Return on average equity -
  continuing operations                         21.9%           21.9%

The increase in working capital at June 30, 1995, with a corresponding
improvement in the current ratio, resulted from increased inventories at the
end of the second quarter consisting of higher quantities of products facing
U.S. generic competition on the basis price and substitution.  In
international markets, inventory levels were up as the result of exchange
fluctuations.  Accounts receivable are also up due to the effects of exchange,
primarily in Europe and Japan, as well as due to a change to self-distribution
in Japan.  The proceeds from the sale of the Asgrow Seed Company also
contributed to the relatively high level of working capital.  A common stock
repurchase program that will utilize approximately $300 million is currently
in the process of implementation.  The ratio of debt to total capitalization
benefited from the increase in total shareholders equity.  The return on
average equity-continuing operations includes the benefit from the sale of the
company's rights under the co-marketing agreement noted above.

Cash from operations in the first six months of 1995 of $253 million decreased
from $311 million due to the increases in inventories and accounts receivable,
noted above.  The current year measure was reduced by approximately $24
million in spending against restructuring reserves established in 1993
compared to $49 million in the first six months of 1994.  There is not
expected to be significant cash spending related to restructuring for the
remainder of the year.  Cash required for the purchase of treasury stock is up
for the first six months of 1995.

See Note G for a discussion of the company's use of derivative financial
instruments.

OTHER ITEMS

In early July 1995, the U.S FDA approved CAVERJECT Sterile Powder (alprostadil
for injection) for the diagnosis and treatment of erectile dysfunction. 
CAVERJECT had already been approved for sale in 25 countries around the world.

All company operations continue to be subject to increased environmental
regulation and legislation, as well as more stringent cleanup requirements and
legal actions (see Notes E and F to the Consolidated Financial Statements). 

The company is unable to predict what effect these matters or any pending or
future legislation, regulations, or government actions may have on its
business.

PART II - OTHER INFORMATION

Item 1. Legal Proceedings

        The Office of Criminal Investigation, U.S. Food and Drug
        Administration, in conjunction with the U.S. Attorney's Office in
        Grand Rapids, Michigan, is conducting a review of the FDA's prior
        Establishment Inspection Report on HALCION, including an assessment of
        the conclusions of the report, the approval of the drug and related
        FDA processes and procedures generally, to determine if there have
        been violations of law and what further action, if any, is
        appropriate.  The company cannot predict the outcome of this review.

Item 6. Exhibits and Reports on Form 8-K.

        (a)(i)     Exhibit A - Report of Independent Accountants (page 14).

        (a)(ii)    Exhibit 11 - Statement regarding computation of earnings
                   per share (page 15).

        (a)(iii)   Exhibit 12 - Ratio of Earnings to Fixed Charges (page 16).
 
        (a)(iv)    Exhibit 15 - Awareness of Coopers & Lybrand (page 17).

        (b)        There were no reports on Form 8-K during the quarter ended
                   June 30, 1995.

SIGNATURE:

Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.



                                           THE UPJOHN COMPANY
                                           (Registrant)
        


DATE:  08/11/95                            /S/R. C. SALISBURY             
                                           R. C. Salisbury
                                           Executive Vice President
                                           and Chief Financial Officer



DATE:  08/11/95                            /S/K. M. CYRUS                 
                                           K. M. Cyrus
                                           Corporate Executive Vice President,
                                           Secretary and General Counsel 


                                 EXHIBIT A






To the Shareholders and 
  Board of Directors
The Upjohn Company

We have reviewed the consolidated balance sheet of The Upjohn Company and
Subsidiaries as of June 30, 1995, the related condensed consolidated
statements of earnings and cash flows for the six-month periods ended June 30,
1995 and 1994.  These financial statements are the responsibility of The
Upjohn Company's management.

We conducted our review in accordance with standards established by the
American Institute of Certified Public Accountants.  A review of interim
financial information consists principally of applying analytical procedures
to financial data and making inquiries of persons responsible for financial
and accounting matters.  It is substantially less in scope that an audit
conducted in accordance with generally accepted auditing standards, the
objective of which is the expression of an opinion regarding the financial
statements taken as a whole.  Accordingly, we do not express such an opinion.

Based on our review, we are not aware of any material modifications that
should be made to the accompanying condensed consolidated financial statements
referred to above, for them to be in conformity with generally accepted
accounting principles.

We have previously audited, in accordance with generally accepted auditing
standards, the consolidated balance sheet as of December 31, 1994, and the
related consolidated statements of earnings, shareholders' equity, and cash
flows for the year ended (not presented herein); and in our report, dated
January 26, 1995, we expressed an unqualified opinion on those consolidated
financial statements.  In our opinion, the information set forth in the
accompanying consolidated balance sheet as of December 31, 1994, is fairly
stated, in all material respects, in relation to the consolidated balance
sheet from which it has been derived.



                                            COOPERS & LYBRAND L.L.P.



Chicago, Illinois
July 18, 1995

<TABLE>
                        THE UPJOHN COMPANY AND SUBSIDIARIES              EXHIBIT 11
                COMPUTATION OF EARNINGS PER COMMON SHARE - PRIMARY
                       (In millions, except per-share data)

<CAPTION>
                                               Three Months         Six Months
                                               Ended June 30,      Ended June 30,
                                                1995     1994      1995    1994 
                                               ------   ------    ------  ------
<S>                                            <C>      <C>       <C>     <C>
Earnings from continuing operations            $115.9   $118.1    $267.5  $242.0
Discontinued operation                                     2.0              12.8
                                               ------   ------    ------  ------
Net earnings                                    115.9    120.1     267.5   254.8
Dividends on preferred stock, net of tax          3.1      3.1       6.2     6.1
                                               ------   ------    ------  ------
Net earnings on common shares - primary        $112.8   $117.0    $261.3  $248.7
                                               ======   ======    ======  ======
Average number of common shares outstanding     171.8    173.0     172.4   173.2
Number of common shares issuable assuming 
  exercise of stock options                       1.1       .1        .8      .1
Contingently issuable incentive common shares      .3       .3        .3      .3
                                               ------   ------    ------  ------
Total shares - primary                          173.2    173.4     173.5   173.6
                                               ======   ======    ======  ======
Primary earnings per common share:
  Earnings from continuing operations          $  .66   $  .66    $ 1.51  $ 1.36
  Discontinued operation                                   .01               .07
                                               ------   ------    ------  ------
  Net earnings                                 $  .66   $  .67    $ 1.51  $ 1.43
                                               ======   ======    ======  ======


             COMPUTATION OF EARNINGS PER COMMON SHARE - FULLY DILUTED

Earnings from continuing operations            $115.9   $118.1    $267.5  $242.0
Discontinued operation                                     2.0              12.8
                                               ------   ------    ------  ------
Net earnings                                    115.9    120.1     267.5   254.8
Less ESOP contribution assumed to be required 
  if preferred shares are converted into 
  common shares                                   1.3      1.3       2.6     2.5
                                               ------   ------    ------  ------
Net earnings on common shares - fully diluted  $114.6   $118.8    $264.9  $252.3
                                               ======   ======    ======  ======
Average number of common shares outstanding     171.8    173.0     172.4   173.2
Number of common shares issuable assuming 
  exercise of stock options                       1.3       .2       1.3      .2
Contingently issuable incentive common shares      .3       .3        .3      .3
Number of common shares issuable assuming 
  conversion of preferred shares                  7.3      7.3       7.3     7.3
                                               ------   ------    ------  ------
Total shares - fully diluted                    180.7    180.8     181.3   181.0
                                               ======   ======    ======  ======
Fully diluted earnings per common share:
  Earnings from continuing operations          $  .63   $  .64    $ 1.46  $ 1.32
  Discontinued operation                                   .01               .07
                                               ------   ------    ------  ------
  Net earnings                                 $  .63   $  .65    $ 1.46  $ 1.39
                                               ======   ======    ======  ======
</TABLE>

<TABLE>
                                                                             EXHIBIT 12

                   THE UPJOHN COMPANY AND CONSOLIDATED SUBSIDIARIES
                   COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES

                             (Dollar amounts in thousands)
<CAPTION>


                             Six Months                 Year Ended December 31,
                               Ended       ----------------------------------------------
                           June 30, 1995    1994     1993     1992     1991    1990
                           -------------    ----     ----     ----     ----    ----
<S>                           <C>        <C>      <C>      <C>      <C>      <C>
Earnings from continuing 
 operations before income 
 taxes                        $376,777   $643,296 $480,037 $671,903 $715,553 $651,800

Less: Asgrow                                                          21,786   26,940

Less: Equity in undistributed
 net income of companies 
 owned less than 50%                99      2,264    3,119    2,212    1,455    1,742
                              --------   -------- -------- -------- -------- --------
                               376,678    641,032  476,918  669,691  692,312  623,118

Add: Amortization of previously 
 capitalized interest            2,475      4,417    4,009    3,799    3,109    2,922

Fixed charges included in the 
 above:
   Interest and amortization of 
   debt expense                 26,313     51,496   58,381   58,155   46,851   53,502

 Rental expense representative 
 of an interest factor           6,451     12,903   12,221   11,495   10,563    9,426
                              --------   -------- -------- -------- -------- --------
Earnings from continuing 
 operations before income 
 taxes and fixed charges      $411,917   $709,848 $551,529 $743,140 $752,835 $688,968
                              ========   ======== ======== ======== ======== ========
Interest incurred and 
 amortization of debt expense $ 31,239   $ 63,599 $ 74,080 $ 69,163 $ 59,920 $ 61,146

Rental expense representative 
 of an interest factor           6,451     12,903   12,221   11,495   10,563    9,426
                              --------   -------- -------- -------- -------- --------
Total fixed charges           $ 37,690   $ 76,502 $ 86,301 $ 80,658 $ 70,483 $ 70,572
                              ========   ======== ======== ======== ======== ========
Ratio of earnings to fixed 
 charges                         10.93       9.28     6.39     9.21    10.68     9.76
                                 =====       ====     ====     ====    =====    =====
</TABLE>

                                 EXHIBIT 15




August 11, 1995




Securities and Exchange Commission
500 North Capital Street
Washington, D.C.  20459

RE:  The Upjohn Company
     Registration on Form 10-Q

We are aware that our report dated July 18, 1995, on our review of interim
financial information of The Upjohn Company and Subsidiaries for the six-month
period ended June 30, 1995 and 1994, included in this Form 10-Q is
incorporated by reference in the Company's prospectus in Form S-3 Registration
Statement (No. 33-31641), the prospectus in Form S-3 Registration Statement
(No. 33-42210), the prospectus in Form S-3 Registration Statement (No. 33-
60304), the prospectus in Form S-8 Registration Statement (No. 33-14461), as
amended and supplemented; in the Form S-8 Registration Statement (No. 33-
15021); and in Form S-8 Registration Statement (No. 33-51659).  Pursuant to
Rule 436(c) under the Securities Act of 1933, this report should not be
considered a part of the registration statement prepared or certified by us
within the meaning of Sections 7 and 11 of the Act.

Very truly yours,



COOPERS & LYBRAND L.L.P.



<TABLE> <S> <C>

<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED
FROM THE EARNINGS STATEMENT AND THE BALANCE SHEET AND IS
QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL
STATEMENTS.
</LEGEND>
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   6-MOS
<FISCAL-YEAR-END>                          DEC-31-1995
<PERIOD-END>                               JUN-30-1995
<CASH>                                         303,914
<SECURITIES>                                         0
<RECEIVABLES>                                  707,305
<ALLOWANCES>                                    35,538
<INVENTORY>                                    502,172
<CURRENT-ASSETS>                             2,141,880
<PP&E>                                       3,203,532
<DEPRECIATION>                               1,351,189
<TOTAL-ASSETS>                               5,243,586
<CURRENT-LIABILITIES>                        1,079,073
<BONDS>                                        515,005<F1>
<COMMON>                                       190,590
                                0
                                    292,719
<OTHER-SE>                                   2,019,070
<TOTAL-LIABILITY-AND-EQUITY>                 5,243,586
<SALES>                                      1,643,446
<TOTAL-REVENUES>                             1,717,569
<CGS>                                          446,828
<TOTAL-COSTS>                                  446,828
<OTHER-EXPENSES>                               290,809<F2>
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                              12,988
<INCOME-PRETAX>                                376,777
<INCOME-TAX>                                   109,300
<INCOME-CONTINUING>                            267,477
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                   267,477
<EPS-PRIMARY>                                     1.51
<EPS-DILUTED>                                     1.46
<FN>
<F1>EXCLUDES COMPANY'S GUARANTEE OF ESOP DEBT:  267,200
<F2>ONLY INCLUDES R&D EXPENSE
</FN>
        

</TABLE>


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