TRIANGLE PHARMACEUTICALS INC
8-A12G/A, 1999-06-18
PHARMACEUTICAL PREPARATIONS
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                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                             ----------------------



                                   FORM 8-A/A
                                 AMENDMENT NO. 1



                FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES
                     PURSUANT TO SECTION 12(B) OR (G) OF THE
                         SECURITIES EXCHANGE ACT OF 1934



                         TRIANGLE PHARMACEUTICALS, INC.
               (Exact name of registrant as specified in charter)


             DELAWARE                       000-21589            56-1930728
(State of incorporation or organization)   (Commission         (IRS Employer
                                           File Number)     Identification No.)

     4 University Place, 4611 University Drive, Durham, North Carolina 27707


        Registrant's telephone number, including area code: (919)493-5980

        Securities to be registered pursuant to Section 12(b) of the Act:

                                      NONE
                                (Title of Class)

        Securities to be registered pursuant to Section 12(g) of the Act:

                         PREFERRED STOCK PURCHASE RIGHTS
                                (Title of Class)

                          NASDAQ NATIONAL MARKET SYSTEM
                               (Name of Exchange)


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Item 1.  DESCRIPTION OF REGISTRANT'S SECURITIES TO BE REGISTERED.

              On June 2, 1999, Triangle Pharmaceuticals, Inc. ("Triangle") and
Abbott Laboratories ("Abbott") executed a Collaboration Agreement (the
"Collaboration Agreement"), a Co-Promotion Agreement (the "Co-Promotion
Agreement"), a Common Stock Purchase Agreement (the "Stock Purchase Agreement"),
and a Stockholder Rights Agreement (the "Stockholder Agreement") (collectively,
the "Alliance Agreements").

              In connection with the Alliance Agreements, the Board of Directors
of Triangle approved an amendment (the "Amendment"), dated as of June 2, 1999 to
the Rights Agreement, dated February 1, 1999, by and between Triangle and
American Stock Transfer & Trust Company, as Rights Agent (the "Rights
Agreement"). All capitalized terms below and not defined herein have the
meanings given them in the Rights Agreement, as amended.

              The Amendment provides that (i) from the Effective Date (as such
term is defined in the Collaboration Agreement) up until such time as Abbott
holds less than the Minimum Purchaser Interest (as such term is defined in the
Stockholder Agreement), neither Abbott nor its U.S. wholly-owned subsidiaries
shall be deemed to be an Acquiring Person, that the Distribution Date will not
be deemed to occur and that the Rights will not separate from the Common Stock
of Triangle as a result of entering into the Alliance Agreements or the
consummation of the transactions contemplated thereby (other than any purchases
permitted under Section 5.3 of the Stockholder Agreement or otherwise which
cause Abbott's Beneficial Ownership (as the term "Beneficial Ownership" is
defined in the Stockholder Agreement) of shares of Triangle's Common Stock to
exceed 21% of the total shares of Common Stock of Triangle outstanding from time
to time hereafter) or as a result of the acquisition by Abbott of Beneficial
Ownership (as defined in the Stockholder Agreement) of shares of Common Stock of
Triangle not exceeding twenty-one percent (21%) of the total shares of Common
Stock of Triangle outstanding from time to time hereafter, and (ii) for the
period commencing as of the date of the Stockholder Agreement and ending on the
earlier of (x) the Effective Date and (y) termination of the Stockholder
Agreement (the "Interim Period"), neither Abbott nor its U.S. wholly-owned
subsidiaries shall be deemed to be an Acquiring Person, that the Distribution
Date will not be deemed to occur and that the Rights will not separate from the
Common Stock as a result solely of Abbott entering into the Stockholder
Agreement and being deemed the Beneficial Owner of the Shares (as defined in the
Stock Purchase Agreement); provided that Abbott does not become the Beneficial
Owner (as defined in the Stockholder Agreement) of any securities of Triangle in
addition to the Shares during the Interim Period.

              The foregoing description of the Amendment does not purport to be
complete and is qualified in its entirety by reference to the full text of the
Amendment and of the Stock Purchase Agreement and Stockholder Agreement filed
herewith or referenced as Exhibits 1 through 3 and incorporated herein by this
reference.


                                       2

<PAGE>


Item 2.  EXHIBITS.

<TABLE>
<S>           <C>
1             Amendment to Rights Agreement, dated as of June 2, 1999, by and
              between Triangle Pharmaceuticals, Inc. and American Stock Transfer
              &Trust Company, as Rights Agent.

+2            Common Stock Purchase Agreement, dated as of June 2, 1999 by and
              between Triangle Pharmaceuticals, Inc., and Abbott Laboratories.

+3            Triangle Pharmaceuticals, Inc. Stockholder Rights Agreement, dated
              as of June 2, 1999 by and between Triangle Pharmaceuticals Inc.
              and Abbott Laboratories.

+             Filed as exhibits to Abbott Laboratories' Schedule 13D filed with
              the Securities and Exchange Commission on June 11, 1999 and
              incorporated herein by reference.

</TABLE>


                                    SIGNATURE

         Pursuant to the requirements of Section 12 of the Securities Exchange
Act of 1934, the registrant has duly caused this registration statement to be
signed on its behalf by the undersigned, thereto duly authorized.



                             TRIANGLE PHARMACEUTICALS, INC.


DATE:  June 18, 1999         By: /s/ James A. Klein, Jr.
                                -----------------------------------
                                Name:  James A. Klein, Jr.
                                Title:  Chief Financial Officer and Treasurer


<PAGE>


                                  EXHIBIT INDEX

<TABLE>
<CAPTION>

EXHIBIT
NUMBER                           DOCUMENT DESCRIPTION
- ------                           --------------------
<S>           <C>
1             Amendment to the Rights Agreement, dated as of June 2, 1999, by
              and between Triangle Pharmaceuticals, Inc. and American Stock
              Transfer & Trust Company as Rights Agent.

+2            Common Stock Purchase Agreement, dated as of June 2, 1999 by and
              between Triangle Pharmaceuticals, Inc. and Abbott Laboratories.

+3            Triangle Pharmaceuticals, Inc. Stockholder Rights Agreement, dated
              as of June 2, 1999 by and between Triangle Pharmaceuticals, Inc.
              and Abbott Laboratories.

+             Filed as exhibits to Abbott Laboratories' Schedule 13D filed with
              the Securities and Exchange Commission on June 11, 1999 and
              incorporated herein by reference.

</TABLE>

<PAGE>


                                    EXHIBIT 1

                          AMENDMENT TO RIGHTS AGREEMENT

              THIS AMENDMENT (the "Amendment"), is entered into as of June 2,
1999, by and between TRIANGLE PHARMACEUTICALS, INC., a Delaware corporation (the
"Company"), and AMERICAN STOCK TRANSFER & TRUST COMPANY, as Rights Agent (the
"Rights Agent").

                                    RECITALS

              A.   The Company and the Rights Agent are parties to a Rights
Agreement dated as of February 1, 1999 (the "Rights Agreement").

              B.   Abbott Laboratories, an Illinois corporation ("Abbott"), and
the Company have entered into a Collaboration Agreement made as of June 2, 1999
(the "Collaboration Agreement"), pursuant to which the parties shall collaborate
with respect to the clinical development, registration, distribution and
marketing of various drugs.

              C.   In connection with the Collaboration Agreement, Abbott and
the Company have entered into, among other agreements, (i) a Common Stock
Purchase Agreement, made as of June 2, 1999 (the "Abbott Stock Purchase
Agreement"), pursuant to which Abbott is to purchase the Shares (as such term is
defined in Section 1.4 of the Abbott Stock Purchase Agreement) and (ii) a
Stockholder Rights Agreement made as of June 2, 1999 (the "Abbott Rights
Agreement").

              D.   Pursuant to Section 3.9 of the Abbott Stock Purchase
Agreement and Section 7.1 of the Abbott Rights Agreement, the Board of Directors
of the Company has determined that an amendment to the Rights Agreement as set
forth herein is necessary and desirable to reflect the foregoing and certain
other matters and the Company and the Rights Agent desire to evidence such
amendment in writing.

              Accordingly, the parties agree that:

         1.   AMENDMENT TO DEFINITION OF "ACQUIRING PERSON" SET FORTH IN SECTION
1(A). The definition of "Acquiring Person" set forth in Section 1(a) of the
Rights Agreement is amended to read in its entirety as follows:

         (a) "Acquiring Person" shall mean any Person (as such term is
         hereinafter defined) who or which, together with all Affiliates and
         Associates (as such terms are hereinafter defined) of such Person,
         shall be the Beneficial Owner (as such term is hereinafter defined) of
         15% or more of the shares of Common Stock of the Company then
         outstanding but shall not include (1) the Company, any Subsidiary (as
         such term is hereinafter defined) of the Company, any employee benefit
         plan of the Company or any Subsidiary of the Company, or any entity
         holding shares of Common Stock for or pursuant to the terms of any such
         plan, (2) during the Interim Period (as defined below), Abbott
         Laboratories, an Illinois corporation (the "Permitted Investor"), or
         any U.S. wholly-owned subsidiaries of Abbott (collectively with the
         Permitted Investor, the


<PAGE>


         "Investor Group") but only to the extent that the Permitted Investor
         may be deemed a Beneficial Owner of the Shares (as defined below) as a
         result of the Permitted Investor entering into the Abbott Stock
         Purchase Agreement (as defined below), unless the Permitted Investor
         becomes the Beneficial Owner (as defined in the Abbott Rights Agreement
         (as defined below)) of any additional securities of the Company other
         than the Shares during the Interim Period, or (3) during the Threshold
         Period (as hereinafter defined), the Investor Group. For purposes of
         this Agreement, the "Interim Period" shall mean such period commencing
         as of the date of the Abbott Stock Purchase Agreement and ending on the
         earlier of (x) the "Effective Date" as such term is defined in the
         Collaboration Agreement (as defined below) and (y) termination of the
         Abbott Stock Purchase Agreement. For purposes of this Agreement, the
         "Threshold Period" shall mean such period commencing as of the
         Effective Date under the Collaboration Agreement and ending on the
         earlier of (xx) such time as the Permitted Investor holds less than the
         Minimum Purchaser Interest in the Company (as defined in Section 1.11
         of the Abbott Rights Agreement), (yy) such time as the Investor Group's
         Beneficial Ownership (as the term Beneficial Ownership is defined in
         the Abbott Rights Agreement) exceeds the Beneficial Ownership
         Limitation (as defined in Section 5.2(a) of the Abbott Rights
         Agreement), and (zz) such time as the Permitted Investor's rights under
         Section 7.1 of the Abbott Rights Agreement have terminated pursuant to
         the terms of the Abbott Rights Agreement. Notwithstanding the
         foregoing:

                        (i)  no Person shall become an "Acquiring Person" as
         the result of an acquisition of shares of Common Stock by the Company
         which, by reducing the number of shares outstanding, (a) increases the
         proportionate number of shares beneficially owned by such Person to 15%
         or more of the shares of Common Stock of the Company then outstanding,
         or, (b) in the case of the Investor Group during the Interim Period,
         increases the proportionate number of shares which may be deemed
         beneficially owned by the Investor Group, unless the Permitted Investor
         becomes the Beneficial Owner (as defined in the Abbott Rights
         Agreement) of any additional securities of the Company other than the
         Shares during the Interim Period, or, (c) in the case of the Investor
         Group during the Threshold Period, increases the proportionate number
         of shares Beneficially Owned (as defined in the Abbott Rights
         Agreement) by the Investor Group to more than the Beneficial Ownership
         Limitation; provided, however, that if by reason of share purchases by
         the Company, (1) a Person shall become the Beneficial Owner of 15% or
         more of the shares of Common Stock of the Company then outstanding or,
         (2) in the case of the Investor Group, the Investor Group's ownership
         increases the Investor Group's Beneficial Ownership (as defined in the
         Abbott Rights Agreement) by any amount during the Interim Period or
         results in the Investor Group's Beneficial Ownership (as defined in the
         Abbott Rights Agreement) to exceed the Beneficial Ownership Limitation
         at any time during the Threshold Period, and, in the case of (1) or (2)
         above, such Person or Investor Group shall, after such share purchases
         by the Company, become the Beneficial Owner of any additional shares of
         Common Stock of the Company, then such Person, including the Investor
         Group, shall be deemed to be an "Acquiring Person" hereunder; and

                        (ii) if the Board of Directors of the Company
         determines in good faith that a Person who would otherwise be an
         "Acquiring Person" as defined pursuant to the


                                       2

<PAGE>


         foregoing provisions of this paragraph (a), has become such
         inadvertently, and such Person divests as promptly as practicable a
         sufficient number of shares of Common Stock so that such Person would
         no longer be an "Acquiring Person" (as defined pursuant to the
         foregoing provisions of this paragraph (a)), then such Person shall not
         be deemed to be an "Acquiring Person" for any purpose of this
         Agreement."

         2.   AMENDMENT TO DEFINITION OF "TRIGGERING EVENT" SET FORTH IN
SECTION 1(OO). The definition of "Triggering Event" set forth in Section 1 (oo)
of the Rights Agreement is amended to add the following sentence to the end
thereof:

         "Notwithstanding anything in this Rights Agreement to the contrary, a
         Triggering Event shall not be deemed to have occurred by virtue of the
         Abbott Stock Purchase Agreement and the Related Agreements (as such
         term is defined in the Abbott Stock Purchase Agreement) or by virtue of
         any of the transactions contemplated thereby (excluding during the
         Interim Period, any purchases which result in the Permitted Investor
         becoming the Beneficial Owner (as defined in the Abbott Rights
         Agreement) of any securities of the Company in addition to the Shares
         and excluding, during the Threshold Period, any purchases permitted by
         Section 5.3 of the Abbott Rights Agreement or otherwise which cause the
         Permitted Investor's Beneficial Ownership (as defined in Section 5.4 of
         the Abbott Rights Agreement) of shares of Common Stock to exceed 21% of
         the then total outstanding shares of Common Stock of the Company)."

         3.   AMENDMENT TO SECTION 1. The following definitions are hereby added
to the end of Section 1 as Sections 1(pp), 1(qq), 1(rr) and 1(ss):

         "(pp) "Abbott Rights Agreement" shall mean that certain Stockholder
         Rights Agreement made as of June 2, 1999, by and between the Company
         and Abbott Laboratories.

         (qq) "Abbott Stock Purchase Agreement" shall mean that certain Common
         Stock Purchase Agreement made as of June 2, 1999, by and between the
         Company and Abbott Laboratories.

         (rr) "Collaboration Agreement" shall mean that certain Collaboration
         Agreement made as of June 2, 1999, by and between the Company and
         Abbott Laboratories.

         (ss) "Shares" shall have the meaning assigned to such term in the
         Abbott Stock Purchase Agreement."

         4.   AMENDMENT OF SECTION 3(A). The first sentence of Section 3(a) of
the Rights Agreement is amended to read in its entirety as follows:

         "Until the earlier of (i) the Close of Business on the Shares
         Acquisition Date and (ii) the Close of Business on the tenth Business
         Day (or such later date as may be determined by action of the Company's
         Board of Directors prior to such time as any Person becomes an
         Acquiring Person and of which the Company will give the Rights Agent
         prompt written notice) after the date that a tender or exchange offer


                                       3

<PAGE>


         by any Person (other than the Company, any Subsidiary of the Company,
         any employee benefit plan of the Company or of any Subsidiary of the
         Company or any entity holding shares of Common Stock for or pursuant to
         the terms of any such plan) is first published or sent or given within
         the meaning of Rule 14d-4(a) of the Exchange Act Regulations or any
         successor rule or of the first public announcement of the intention of
         any Person (other than the Company, any Subsidiary of the Company, any
         employee benefit plan of the Company or of any Subsidiary of the
         Company or any entity holding shares of Common Stock for or pursuant to
         the terms of any such plan) to commence, a tender or exchange offer, if
         upon consummation thereof such Person would be the Beneficial Owner of
         15% or more of the shares of Company Common Stock then outstanding, or,
         in the case of the Investor Group during the Interim Period, the
         Investor Group purchases any securities of the Company which result in
         the Permitted Investor becoming the Beneficial Owner (as defined in the
         Abbott Rights Agreement) of any securities of the Company in addition
         to the Shares, or in the case of the Investor Group during the
         Threshold Period, the Permitted Investor's Beneficial Ownership (as
         defined in the Abbott Rights Agreement) would exceed the Beneficial
         Ownership Limitation (as defined in the Abbott Rights Agreement), (the
         earlier of (i) and (ii) above being the "Distribution Date"), (x) the
         Rights will be evidenced (subject to the provisions of Section 3(b)
         hereof) by the certificates for shares of Common Stock registered in
         the names of the holders thereof (which certificates shall also be
         deemed to be Rights Certificates) and not by separate Rights
         Certificates, and (y) the right to receive Rights Certificates will be
         transferable only in connection with the transfer of shares of Common
         Stock."

         5.   MISCELLANEOUS. This Amendment shall be deemed to be a contract
made under the laws of the State of Delaware and for all purposes shall be
governed by and construed in accordance with the laws of such State applicable
to contracts to be made and performed entirely within such State. This Amendment
may be executed in any number of counterparts, each of such counterparts shall
for all purposes be deemed to be an original, and all such counterparts shall
together constitute but one and the same instrument. If any term, provision,
covenant or restriction of this Amendment is held by a court of competent
jurisdiction or other authority to be invalid, void or unenforceable, the
remainder of the terms, provisions, covenants and restrictions of this Amendment
shall remain in full force and effect and shall in no way be affected, impaired
or invalidated.


                                        4

<PAGE>


         IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
duly executed and attested, all as of the day and year first above written.


ATTEST:                           TRIANGLE PHARMACEUTICALS, INC.



By: /s/ Chris A. Rallis               By: /s/ David Barry
   -----------------------------         ----------------------------
    Name:  Chris A. Rallis          Name:  David Barry
         -----------------------         -------------------------
    Title: General Counsel          Title: Chief Executive Officer
          ----------------------          ------------------------


ATTEST:                           AMERICAN STOCK TRANSFER & TRUST
                                  COMPANY



By: /s/ Barry S. Rosenthal        By: /s/ Herbert J. Lemmer
   -----------------------------     --------------------------
    Name:  Barry S. Rosenthal     Name:  Herbert J. Lemmer
         -----------------------       ------------------------
    Title: Vice President         Title: Vice President
          ----------------------        -----------------------


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