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- -------- UNITED STATES SECURITIES AND EXCHANGE COMMISSION -----------------------------
FORM 4 WASHINGTON, D.C. 20549 OMB APPROVAL
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/ / CHECK THIS BOX IF NO STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OMB NUMBER: 3235-0287
LONGER SUBJECT TO EXPIRES: SEPTEMBER 30, 1998
SECTION 16. FORM 4 OR Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, ESTIMATED AVERAGE BURDEN
FORM 5 OBLIGATIONS MAY Section 17(a) of the Public Utility Holding Company Act of 1935 or HOURS PER RESPONSE .... 0.5
CONTINUE. SEE Section 30(f) of the Investment Company Act of 1940 -----------------------------
INSTRUCTION 1(b).
(Print or Type Responses)
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1. Name and Address of Reporting Person* 2. Issuer Name and Ticker or Trading Symbol 6. Relationship of Reporting Person(s)
to Issuer (Check all applicable)
X Director 10% Owner
Fleming Standish M. Triangle Pharmaceuticals, Inc. (VIRS) ---- ----
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(Last) (First) (Middle) 3. IRS or Identification 4. Statement for ---- title ---- (specify
Number of Reporting Month/Year below) below)
c/o Forward Ventures Person, if an entity ----------------- ------------------
9255 Towne Centre Drive, Suite 300 (Voluntary) March 1999
- -------------------------------------------- --------------------- 7. Individual or Joint/Group Filing
(Street) 5. If Amendment, (check applicable line)
Date of Original X Form filed by One Reporting Person
San Diego California 92121 (Month/Year) ___Form filed by More than One
Reporting person
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(City) (State) (Zip) TABLE I - NON-DERIVATIVE SECURITIES BENEFICIALLY OWNED
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1. Title of Security 2. Trans- 3. Trans- 4. Securities Acquired (A) 5. Amount of 6. Owner- 7. Nature
(Instr. 3) action action or Disposed of (D) Securities ship of In-
Date Code (Instr. 3, 4 and 5) Beneficially Form: direct
(Instr. 8) Owned at Direct Bene-
(Month/ End of (D) or ficial
Day/ ------------------------------------------- Month Indirect Owner-
Year) (A) or (I) ship
Code V Amount (D) Price (Instr. 3 (Instr. 4) (Instr. 4)
and 4)
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Common Stock 3/2/99 J(1) V 4,147 A 87,975 D
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Common Stock 3/2/99 J(1) V 2,047 A 2,047(2) I By family
trust
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Common Stock 3/2/99 J(1) V 2,047 A 2,775*(3) I By children's
trust
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Common Stock 3/2/99 J(1) V 2,175 A 2,175*(4) I By limited
partnership
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Common Stock 3/2/99 J(1) V 100,000 D 925,000*(5) I By general
partnership
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Common Stock 233,663*(6) I By general
partnership
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Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. (Over)
* If this form is filed by more than one reporting person, SEE Instruction 5(b)(v). SEC 1474 (7-97)
POTENTIAL PERSONS WHO ARE TO RESPOND TO THE COLLECTION OF INFORMATION
CONTAINED IN THIS FORM ARE NOT REQUIRED TO RESPOND UNLESS THE FORM
DISPLAYS A CURRENTLY VALID OMB NUMBER.
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FORM 4 (CONTINUED) TABLE II - DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
(E.G., PUTS, CALLS, WARRANTS, OPTIONS, CONVERTIBLE SECURITIES)
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1. Title of Derivative Security 2. Conver- 3. Trans- 4. Transac- 5. Number of Deriv- 6. Date Exer-
(Instr. 3) sion or action tion Code ative Securities Ac- cisable and Ex-
Exercise Date (Instr. 8) quired (A) or Dis- piration Date
Price of (Month/ posed of (D) (Month/Day/
Deriv- Day/ (Instr. 3, 4, and 5) Year)
ative Year)
Security
Date Expira-
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Code V (A) (D) cisable Date
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7. Title and Amount of Under- 8. Price 9. Number 10. Owner- 11. Nature
lying Securities of of Deriv- ship of In-
(Instr. 3 and 4) Deriv- ative Form direct
ative Securi- of De- Bene-
Secur- ties rivative ficial
ity Bene- Secu- Own-
(Instr. ficially rity: ership
5) Owned Direct (Instr. 4)
at End (D) or
Amount or of Indi-
Title Number of Month rect (I)
Shares (Instr. 4) (Instr. 4)
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Explanation of Responses:
* Mr Fleming disclaims beneficial ownership of these shares other than to
the extent of his individual partnership and member pecuniary interests.
(1) Represents a distribution of 100,000 shares made by Forward Ventures II,
L.P., of which Forward II Associates, L.P. is the general partner, of
which Mr. Fleming is a general partner.
In prior reports, Mr. Fleming has reported beneficial ownership of the
distributed shares.
(2) Represents shares held by the Fleming Family Trust, of which Mr. Fleming
is a co-trustee.
(3) Represents all shares held by the Fleming Family Children's Trust, of which
Mr. Fleming is a co-trustee.
(4) Represents all shares held by Forward II Associates, L.P. (to the extent of
its own partnership interest in Forward Ventures II, L.P).
(5) Represents all shares held by Forward Ventures II, L.P.
(6) Represents all shares held by Forward Ventures III, L.P., of which Forward
III Associates, L.L.C. is the general partner, of which Mr. Fleming is a
managing member.
/s/ STANDISH M. FLEMING 4/12/99
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**Signature of Reporting Person Date
**Intentional misstatements or omissions of facts constitute
Federal Criminal Violations. SEE 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed.
If space is insufficient, SEE Instruction 6 for procedure.
POTENTIAL PERSONS WHO ARE TO RESPOND TO THE COLLECTION OF INFORMATION
CONTAINED IN THIS FORM ARE NOT REQUIRED TO RESPOND UNLESS THE FORM DISPLAYS A
CURRENTLY VALID OMB NUMBER.
Page 2
SEC 1474 (7-97)