CORNING PHARMACEUTICAL SERVICES INC
10-12B/A, 1996-11-19
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

   
                                    Form 10/A
                           Amendment No. 2 to Form 10
    

                   General Form For Registration of Securities
                       Pursuant to Section 12(b) or (g) of
                       the Securities Exchange Act of 1934

                                  COVANCE INC.
            (formerly known as Corning Pharmaceutical Services Inc.)
             (Exact name of registrant as specified in its charter)

           Delaware                                       22-3265977 
- --------------------------------------------------------------------------
    (State or other jurisdiction of                     (I.R.S. Employer 
    incorporation or organization)                     Identification No.)

       210 Carnegie Center 
       Princeton, New Jersey                              08540-6233 
- --------------------------------------------------------------------------
(Address of principal executive offices)                  (Zip Code) 


                                  609 452 4440
              ----------------------------------------------------
              (Registrant's telephone number, including area code)

        Securities to be registered pursuant to Section 12(b) of the Act:

         Title of each class                  Name of each exchange on which 
          to be so registered                   each class is to be registered 

Common Stock, with attached Preferred            New York Stock Exchange 
        Stock Purchase Right 

Securities to be registered pursuant to Section 12(g) of the Act: 

                                      None
- --------------------------------------------------------------------------------
                                (Title of class)


<PAGE>

                                  COVANCE INC.

   
INTRODUCTION
     This Registration Statement on Form 10 relates to the registration under
the Securities Exchange Act of 1934, as amended, of the common stock, with
attached Preferred Stock Purchase Right, of the Registrant which is being issued
as described in the Information Statement, subject to completion or amendment
(the "Information Statement"), dated November 19, 1996, of Corning
Incorporated. Selected pages of the Information Statement which are related to
the Registrant and the securities being registered hereunder (the "Covance
Information") are attached hereto as Exhibit 99.1 and are incorporated herein by
reference in answer to the items of this Registration Statement set forth below.

Item 1. Business
     The information required by this item is contained under the sections "Risk
Factors--Risks Relating to Covance," "Business of Covance" and "The Relationship
Among Corning, Quest Diagnostics and Covance After the Distributions" of the
Covance Information and such sections are incorporated herein by reference.
    

Item 2. Financial Information
     The information required by this item is contained under the sections
"Capitalization of Covance", "Pro Forma Financial Information of Covance,"
"Selected Historical Financial Data of Covance" and "Management's Discussion
and Analysis of Financial Condition and Results of Operations of Covance" of the
Covance Information and such sections are incorporated herein by reference.

Item 3. Properties
     The information required by this item is contained under the sections
"Business of Covance--Facilities" and "Business of Covance--Services--
Biomanufacturing" of the Covance Information, and such sections are incorporated
herein by reference.

Item 4. Security Ownership of Certain Beneficial Owners and Management
     The information required by this item is contained under the section
"Security Ownership of Certain Beneficial Owners and Management of Covance" of
the Covance Information and such section is incorporated herein by reference.

Item 5. Directors and Executive Officers
     The information required by this item is contained under the section
"Management of Covance" of the Covance Information and such section is
incorporated herein by reference.

Item 6. Executive Compensation
     The information required by this item is contained under the section
"Management of Covance" of the Covance Information and such section is
incorporated herein by reference.

Item 7. Certain Relationships and Related Transactions
     The information required by this item is contained under the section
"Management of Covance" of the Covance Information and such section is
incorporated herein by reference.

Item 8. Legal Proceedings
     The information required by this item is contained under the section
"Business of Covance--Legal Proceedings" of the Covance Information and such
section is incorporated herein by reference.

                                       2
<PAGE>

   
Item 9. Market Price of and Dividends on the Registrant's Common Equity and
        Related Stockholder Matters
     The information required by this item is contained under the sections "Risk
Factors--Risks Relating to Covance--Absence of Dividends; Restrictions Imposed
on Dividends by the Covance Credit Facility," "Risk Factors--Risks Relating to
Covance--Absence of Prior Public Market," "Risk Factors--Risks Relating to
Covance--Potential Volatility of Stock Price," "Description of Covance Capital
Stock--Covance Common Stock--Dividend Policy," "--Covance Common Stock--Listing
and Trading" and "Management of Covance" of the Covance Information and such
sections are incorporated herein by reference.
    

Item 10. Recent Sales of Unregistered Securities
     Not applicable.

Item 11. Description of Registrant's Securities to be Registered
     The information required by this item is contained under the sections
"Description of Covance Capital Stock" and "Antitakeover Effects of Certain
Provisions of the Covance Certificate of Incorporation and By-Laws" of the
Covance Information and such sections are incorporated herein by reference.

Item 12. Indemnification of Directors and Officers
     The information required by this item is contained under the section
"Liability and Indemnification of Directors and Officers of Covance" of the
Covance Information and such section is incorporated herein by reference.

Item 13. Financial Statements and Supplementary Data
     The information required by this item is contained under the sections
"Capitalization of Covance," "Pro Forma Financial Information of Covance,"
"Selected Historical Financial Data of Covance," "Management's Discussion and
Analysis of Financial Condition and Results of Operations of Covance" and
"Financial Statements of Covance Inc." of the Covance Information and such
sections are incorporated herein by reference.

Item 14. Changes in and Disagreements with Accountants on Accounting and
         Financial Disclosure
     Not applicable.

Item 15. Financial Statements and Exhibits
     (a) Financial Statements

     The information required by this item is contained under the section
"Financial Statements of Covance Inc." of the Covance Information and such
section is incorporated herein by reference.
     (b) Exhibits

                                       3
<PAGE>


   
<TABLE>
<CAPTION>
<S>           <C>
Exhibit 
Number                                              Description 
- --------      --------------------------------------------------------------------------------------- 
 2.1          Form of Transaction Agreement among Corning Incorporated, Corning Life Sciences Inc., 
              Corning Clinical Laboratories Inc. and Covance Inc., dated [      ], 1996 
 3.1          Certificate of Incorporation of the Registrant 
 3.2          By-Laws of the Registrant 
 4.1*         Form of Common Stock certificate 
 4.2          Form of Rights Agreement between Covance Inc. and Harris Trust and Savings Bank, dated 
              December 31, 1996 
10.1          Form of Tax Sharing Agreement among Corning Incorporated, Corning Clinical Laboratories 
              Inc. and Covance Inc., dated [      ], 1996 
10.2          Form of Spin-Off Tax Indemnification Agreement between Corning Incorporated and Covance 
              Inc., dated [      ], 1996 
10.3          Form of Spin-Off Tax Indemnification Agreement between Covance Inc. and Corning 
              Clinical Laboratories Inc., dated [      ], 1996 
10.4          Form of Spin-Off Tax Indemnification Agreement between Corning Clinical Laboratories, 
              Inc. and Covance Inc., dated [      ], 1996 
10.5*         Form of Credit Agreement among Covance Inc., Nationsbank, N.A., Wachovia Bank of 
              Georgia, N.A. and the Lenders named therein, dated [      ], 1996 
10.6*         Form of Covance Inc. Employee Stock Ownership Plan 
10.7*         Form of Covance Inc. Stock Purchase Savings Plan 
10.8          Form of Covance Inc. Employees Stock Purchase Program 
10.9          Form of Covance Inc. Employee Equity Participation Program 
10.10*        Form of Covance Inc. Executive Retirement Supplemental Plan 
10.11         Form of Covance Inc. Restricted Share Plan 
10.12*        Form of Covance Inc. Directors' Restricted Stock Plan 
10.13*        Form of Covance Inc. Directors' Deferred Compensation Plan 
10.14         Form of Employment Agreement between Christopher Kuebler and Covance Inc. 
21            Subsidiaries of the Registrant 
27            Financial Data Schedules 
99.1          Selected pages of the Information Statement, subject to completion or amendment, of 
              Corning Incorporated dated November 19, 1996 (pages 2; 28-31; 108-168; F-1; F-29-F-44) 
</TABLE>
    
- ------------- 
* To be filed by amendment. 

                                      4 


<PAGE>

                                   SIGNATURES

     Pursuant to the requirements of Section 12 of the Securities Exchange Act
of 1934, the registrant has duly caused this amendment to the registration
statement to be signed on its behalf by the undersigned, thereunto duly
authorized.

                            COVANCE INC. 

   
Dated: November 19, 1996    By: /s/ Jeffrey S. Hurwitz
                            ------------------------------------------
                            Jeffrey S. Hurwitz, Corporate Senior Vice President,
                            General Counsel and Secretary 
    

                                       5


                                                                       S&S DRAFT

                  ---------------------------------------------

                              TRANSACTION AGREEMENT

                  ---------------------------------------------



                          dated as of __________, 1996

                                  by and among

                              CORNING INCORPORATED,

                           CORNING LIFE SCIENCES INC.,

                       CORNING CLINICAL LABORATORIES INC.

                                       and

                                  COVANCE INC.






<PAGE>



                                TABLE OF CONTENTS


                                                                            Page

                                    ARTICLE I
                                   DEFINITIONS

SECTION 1.01.        General.................................................  2
SECTION 1.02.        References; Interpretation..............................  7

                                   ARTICLE II
             DISTRIBUTIONS AND OTHER TRANSACTIONS; CERTAIN COVENANTS

SECTION 2.01.        Conditions Precedent....................................  7
SECTION 2.02.        The Distributions and Other Transactions................  8
SECTION 2.03.        Treatment of Fractional Shares.......................... 12
SECTION 2.04.        Certain Intercompany Financial and Other Arrangements... 12
SECTION 2.05.        Certain Indebtedness and Capital Structure.............. 13
SECTION 2.06.        Further Assurances...................................... 13
SECTION 2.07.        No Representations or Warranties........................ 13
SECTION 2.08.        Guarantees.............................................. 13
SECTION 2.09.        Certain Transactions.................................... 14
SECTION 2.10.        Insurance............................................... 14

                                   ARTICLE III
                                 INDEMNIFICATION

SECTION 3.01.        Indemnification by Corning.............................. 14
SECTION 3.02.        Indemnification by CCL.................................. 19
SECTION 3.03.        Indemnification by Covance.............................. 19
SECTION 3.04.        Adjustments for Indemnification Obligations............. 19
SECTION 3.05.        Procedures for Indemnification - Third Party Claims..... 19
SECTION 3.06.        Survival of Indemnities................................. 21
SECTION 3.07.        Payments................................................ 21

                                   ARTICLE IV
                              ACCESS TO INFORMATION

SECTION 4.01.        Provision of Corporate Records.......................... 21
SECTION 4.02.        Access to Information................................... 22
SECTION 4.03.        Reimbursement........................................... 22
SECTION 4.04.        Confidentiality......................................... 22


<PAGE>


                                       ii

                                    ARTICLE V
                               DISPUTE RESOLUTION

SECTION 5.01.        Good Faith Negotiations................................. 23
SECTION 5.02.        Procedure............................................... 23

                                   ARTICLE VI
                               GENERAL PROVISIONS

SECTION 6.01.        Expenses................................................ 24
SECTION 6.02.        Notices................................................. 24
SECTION 6.03.        Complete Agreement; Construction........................ 25
SECTION 6.04.        Ancillary Agreements.................................... 25
SECTION 6.05.        Counterparts............................................ 25
SECTION 6.06.        Survival of Agreements.................................. 25
SECTION 6.07.        Waiver.................................................. 25
SECTION 6.08.        Amendments.............................................. 26
SECTION 6.09.        Assignment.............................................. 26
SECTION 6.10.        Successors and Assigns.................................. 26
SECTION 6.11.        Termination............................................. 26
SECTION 6.12.        Subsidiaries............................................ 26
SECTION 6.13.        Third Party Beneficiaries............................... 26
SECTION 6.14.        Headings................................................ 27
SECTION 6.15.        Specific Performance.................................... 27
SECTION 6.16.        Governing Law........................................... 27
SECTION 6.17.        Public Announcements.................................... 27
SECTION 6.18.        Severability............................................ 27



<PAGE>


                                       iii

SCHEDULES

Schedule 2.08     Guarantees


EXHIBITS

Exhibit A         Forms of Contribution Agreement, Liabilities Undertaking,
                  Bill of Sale and Assignment and Instrument of Assignment
                  and Assumption
Exhibit B         Form of Plan of Liquidation and Dissolution of CLSI
Exhibit C         Certificate of Ownership and Merger and Certificate of Merger,
                  with attached Agreement and Plan of Merger and Complete
                  Liquidation (CBI into Covance)
Exhibit D         Form of Insurance Agreement
Exhibit E         Form of Services Agreement
Exhibit F         Form of Spin-off Tax Indemnification Agreements
Exhibit G         Form of Tax Sharing Agreement
Exhibit H         Forms of Amended Charter and By-Laws of CCL
Exhibit I         Forms of Amended Charter and By-Laws of Covance

<PAGE>


                  TRANSACTION AGREEMENT dated as of November __, 1996, by and
among CORNING INCORPORATED, a New York corporation ("Corning"), CORNING LIFE
SCIENCES INC., a Delaware corporation ("CLSI"), CORNING CLINICAL LABORATORIES
INC., a Delaware corporation ("CCL"), and COVANCE INC., a Delaware corporation
("Covance").


                              W I T N E S S E T H:

                  WHEREAS, Corning is  the common parent of a consolidated group
which includes CLSI, CCL and Covance;

                  WHEREAS, the Board of Directors of Corning has determined that
it is appropriate and desirable to distribute to the holders of shares of common
stock, par value $0.50 per share, of Corning (the "Corning Common Shares") all
the outstanding shares of common stock of CCL (the "CCL Common Stock") and,
immediately following such distribution, for CCL to distribute to the holders of
CCL Common Stock all the outstanding shares of common stock of Covance (the
"Covance Common Stock");

                  WHEREAS, each of Corning, CCL and Covance has determined that
it is necessary and desirable to set forth the principal corporate transactions
required to effect such distribution and to set forth other agreements that will
govern certain other matters following the distribution;

                  WHEREAS, each of Corning, CCL and Covance has determined that
it is necessary and desirable to allocate and assign responsibility for those
liabilities in respect of the activities of the businesses of such entities on
the Distribution Date (as defined herein) and those liabilities in respect of
other businesses and activities of Corning and its former subsidiaries and other
matters;

                  WHEREAS, Corning currently owns 100% of the stock of CLSI;

                  WHEREAS, CLSI currently owns 100% of the stock of CCL;

                  WHEREAS, CCL currently owns 100% of the stock of Covance;

                  WHEREAS, Covance currently owns 100% of the stock of Corning
Besselaar, Inc. ("CBI"); and



<PAGE>


                                        2

                  WHEREAS, prior to the Distribution Date, CLSI will contribute
to CCL substantially all of its assets other than the stock of CCL in exchange
for additional shares of CCL Common Stock and shares of nonvoting preferred
stock of CCL and Corning will cause CLSI to dissolve and CBI to be merged with
and into Covance.

                  NOW, THEREFORE, in consideration of the mutual agreements,
provisions and covenants contained in this Agreement, the parties hereby agree
as follows:


                                    ARTICLE I
                                   DEFINITIONS

                  SECTION 1.01. General. As used in this Agreement, the
following terms shall have the following meanings (such meanings to be equally
applicable to both the singular and plural forms of the terms defined):

                  "Action" shall mean any action, suit, arbitration, inquiry,
proceeding or investigation by or before any court, any governmental or other
regulatory or administrative agency, body or commission or any arbitration
tribunal.

                  "Affiliate" shall mean, when used with respect to a specified
person, another person that directly, or indirectly through one or more
intermediaries, will control or will be controlled by or will be under common
control with the person specified immediately following the Effective Time.

                  "Agent" shall have the meaning as defined in Section 2.02(g).

                  "Agreement Disputes" shall have the meaning as defined in
Section 5.01.

                  "Ancillary Agreements" shall mean the Insurance Agreement, the
Intellectual Property Agreement, the Services Agreement, the Spin-off Tax
Indemnification Agreements and the Tax Sharing Agreement.

                  "Assignee" shall have the meaning as defined in Section
2.02(i)(ii).

                  "CCL" shall mean Corning Clinical Laboratories Inc., a
Delaware corporation.

                  "CCL Business" shall mean all businesses and operations
conducted by (i) CLSI, MRL Nucor, Inc. and all current and former subsidiaries
of CLSI (other than CORNING Bio Inc., Covance and its Subsidiaries,
Pharmaceutical Laboratory Services, Inc., Quanterra Incorporated, California
Analytical Laboratory, Chemical Research Laboratories,


<PAGE>


                                        3

Inc., Enseco Incorporated, ERCO, Rocky Mountain Analytical Laboratory and
Wadsworth/Alert Laboratories, Inc.), including without limitation CCL (but
excluding in any event the environmental testing business previously conducted
by CCL); and (ii) any business entities acquired or established by or for CCL or
any of its Subsidiaries after the date of this Agreement.

                  "CCL Indemnitees" shall mean CCL, each Affiliate of CCL, each
of their respective directors and officers and each of the heirs, executors,
successors and assigns of any of the foregoing.

                  "CCL Liabilities" shall mean, collectively, (i) all the
Liabilities of CCL and its Subsidiaries under this Agreement and any of the
Ancillary Agreements, and (ii) all the Liabilities of the parties hereto or
their respective Subsidiaries (whenever arising whether prior to, at or
following the Effective Time) arising out of or in connection with or otherwise
relating to the management or conduct before or after the Effective Time of the
CCL Business.

                  "CCL Record Holders" shall mean all holders of CCL Common
Stock as of the Distribution Record Date, provided that the CCL Record Holders
shall be deemed to be determined immediately following the distribution of CCL
Common Stock to all Corning Record Holders.

                  "CLSI" shall mean Corning Life Sciences Inc., a Delaware
corporation.

                  "Code" shall mean the Internal Revenue Code of 1986, as
amended, and the Treasury regulations promulgated thereunder, including any
successor legislation.

                  "Commission" mean the Securities and Exchange Commission.

                  "Company Policies" shall mean all Policies, current or past,
which are or at any time were maintained by or on behalf of or for the benefit
or protection of Corning or any of its predecessors which relate to the Corning
Business, the CCL Business or the Covance Business, or current or past
directors, officers, employees or agents of any of the foregoing Businesses.

                  "Corning" shall mean Corning Incorporated, a New York
corporation.

                  "Corning Business" shall mean (i) all businesses and
operations of Corning and its subsidiaries other than the CCL Business and the
Covance Business and (ii) the environmental testing business previously
conducted by CCL and its Subsidiaries, including California Analytical
Laboratory, Chemical Research Laboratories, Inc., Enseco


<PAGE>


                                        4

Incorporated, ERCO, Quanterra Incorporated, Rocky Mountain Analytical Laboratory
and Wadsworth/Alert Laboratories, Inc.

                  "Corning Indemnitees" shall mean Corning, each Affiliate of
Corning, each of their respective directors and officers and each of the heirs,
executors, successors and assigns of any of the foregoing.

                  "Corning Liabilities" shall mean all the Liabilities of
Corning and its Subsidiaries under this Agreement and any of the Ancillary
Agreements, and all the Liabilities of Corning and its subsidiaries that are not
CCL Liabilities or Covance Liabilities including, without limitation, all
Liabilities under any employee benefit plans maintained by Corning and any stock
option employment or consulting agreements to which Corning is a party,
including any such benefit plans or agreements covering or with persons who are
or were employees of CCL or Covance and their respective Subsidiaries.
Notwithstanding the foregoing, the remaining payment obligations under the
Agreement dated June 7, 1995 among Corning, CLSI and Ralph H. Thurman and the
Consulting Agreement dated June 7, 1995 among Corning, CLSI and Ralph H. Thurman
shall be CCL Liabilities and not Corning Liabilities.

                  "Corning Record Holders" shall mean all holders of record of
Corning Common Shares as of the Distribution Record Date.

                  "Covance" shall mean Corning Pharmaceutical Services Inc., a
Delaware corporation.

                  "Covance Business" shall mean all businesses and operations
conducted by (i) all current and former subsidiaries of Covance and by CORNING
Bio Inc. and Pharmaceutical Laboratory Services, Inc. prior to the Effective
Time; and (ii) any business entities acquired or established by or for Covance
or any of its Subsidiaries after the date of this Agreement.

                  "Covance Indemnitees" shall mean Covance, each Affiliate of
Covance, each of their respective directors and officers and each of the heirs,
executors, successors and assigns of any of the foregoing.

                  "Covance Liabilities" shall mean, collectively, (i) all the
Liabilities of Covance and its Subsidiaries under this Agreement and any of the
Ancillary Agreements, and (ii) all the Liabilities of the parties hereto or
their respective Subsidiaries (whenever arising whether prior to, at or
following the Effective Time) arising out of or in connection with or otherwise
relating to the management or conduct before or after the Effective Time of the
Covance Business.



<PAGE>


                                        5

                  "Distribution Date" shall mean December 31, 1996 or such later
date as may hereafter be determined by Corning's Board of Directors as the date
as of which the Distributions shall be effected.

                  "Distribution Record Date" shall mean December 31, 1996 or
such later date as may hereafter be determined by Corning's Board of Directors
as the record date for the Distributions.

                  "Distributions" shall mean the two consecutive distributions
in the following order on the Distribution Date to (i) all Corning Record
Holders of the CCL Common Stock owned by Corning and (ii) all CCL Record Holders
of the Covance Common Stock owned by CCL.

                  "Effective Time" shall mean 11:59 p.m., New York time, on the
Distribution Date.

                  "Exchange Act" shall mean the Securities and Exchange Act of
1934, as amended.

                  "Indemnifiable Losses" shall mean any and all losses,
liabilities, claims, damages, demands, costs or expenses (including, without
limitation, reasonable attorneys' fees and any and all reasonable and necessary
out-of-pocket expenses) whatsoever, including any and all losses, liabilities,
claims, damages, demands, costs or expenses reasonably incurred in
investigating, preparing for or defending against any Actions or potential
Actions, provided, however, that such Indemnifiable Losses shall not include
Taxes or other amounts indemnified against under the Spin-off Tax
Indemnification Agreements and the Tax Sharing Agreement.

                  "Indemnifying Party" shall have the meaning as defined in
Section 3.04.

                  "Indemnitee" shall have the meaning as defined in Section 
3.04.

                  "Information Statement" shall mean the Information Statement
sent to all the Record Holders in connection with the Distributions, including
any amendment or supplement thereto.

                  "Insurance Agreement" shall mean the Insurance Agreement among
Corning, CCL and Covance, in substantially the form attached hereto as Exhibit
D.

                  "Intellectual Property Agreement" shall mean the Intellectual
Property and Licensing Agreement among Corning, CCL and Covance, in a form to be
agreed upon by the parties to this Agreement.


<PAGE>


                                        6


                  "Liabilities" shall mean any and all debts, liabilities and
obligations, absolute or contingent, matured or unmatured, liquidated or
unliquidated, accrued or unaccrued, known or unknown, whenever arising,
including, without limitation, those debts, liabilities and obligations arising
under any law, rule, regulation, Action, threatened Action, order or consent
decree of any court, any governmental or other regulatory or administrative
agency or commission or any award of any arbitration tribunal, and those arising
under any contract, guarantee, commitment or undertaking.

                  "person" shall mean any natural person, corporation, business
trust, joint venture, association, company, partnership or government, or any
agency or political subdivision thereof.

                  "Policies" shall mean insurance policies and insurance
contracts of any kind (other than life and benefits policies or contracts),
including, without limitation, primary, excess and umbrella policies,
comprehensive general liability policies, fiduciary liability, automobile,
aircraft, property and casualty, workers' compensation and employee dishonesty
insurance policies, bonds and self-insurance and captive insurance company
arrangements, together with the rights, benefits and privileges thereunder.

                  "Record Holders" shall mean the CCL Record Holders and the
Corning Record Holders, collectively.

                  "Records" shall have the meaning as defined in Section 4.01.

                  "Registration Statements" shall mean the registration
statements on Form 10 in respect of the CCL Common Stock and the Covance Common
Stock required to be filed with the Commission pursuant to Rule 12(b) under the
Exchange Act.

                  "Rules" shall have the meaning as defined in Section 5.02.

                  "Services Agreement" shall mean the Services Agreement among
Corning, CCL and Covance, in substantially the form attached hereto as Exhibit
E.

                  "Spin-off Tax Indemnification Agreement" shall mean each of
the Spin-off Tax Indemnification Agreements between or among two or more of
Corning, CCL and Covance, in substantially the form attached hereto as Exhibit
F.

                  "Subsidiary" shall mean any corporation, partnership or other
entity of which another entity (i) will own, immediately following the Effective
Time, directly or indirectly, ownership interests sufficient to elect a majority
of the board of directors (or persons performing similar functions)
(irrespective of whether at the time any other class or classes of ownership
interests of such corporation, partnership or other entity shall or might have


<PAGE>


                                        7

such voting power upon the occurrence of any contingency) or (ii) will be,
immediately following the Effective Time, a general partner or an entity
performing similar functions; provided that Bio Imaging Technologies Inc. will
be deemed to be a Subsidiary of Covance and, National Imaging Associates will be
deemed to be a Subsidiary of CCL, in each case, for all purposes of this
Agreement.

                  "Tax" shall mean all federal, state, local and foreign gross
or net income, gross receipts, withholding, franchise, transfer, estimated or
other tax or similar charges and assessments, including all interest, penalties
and additions imposed with respect to such amounts.

                  "Tax Sharing Agreement" shall mean the Tax Sharing Agreement
among Corning, CCL and Covance, in substantially the form attached hereto as
Exhibit G.

                  "Third Party Claim" shall have the meaning as defined in
Section 3.05.

                  SECTION 1.02. References; Interpretation. References to an
"Exhibit" or to a "Schedule" are, unless otherwise specified, to one of the
Exhibits or Schedules attached to this Agreement, and references to a "Section"
are, unless otherwise specified, to one of the Sections of this Agreement.


                                   ARTICLE II
             DISTRIBUTIONS AND OTHER TRANSACTIONS; CERTAIN COVENANTS

                  SECTION 2.01. Conditions Precedent. Neither the Distributions
nor the related transactions set forth in this Agreement or in the Ancillary
Agreements shall become effective unless the following conditions have been
satisfied or waived by Corning on or before the Effective Time:

                  (a)      The Registration Statements shall have been filed by
                           CCL and Covance, as applicable, with, and declared
                           effective by, the Commission and the Information
                           Statement shall have been mailed in a timely manner
                           to all holders of Corning Common Shares prior to the
                           Distribution Date.

                  (b)      Corning shall have received a favorable ruling from
                           the Internal Revenue Service to the effect that the
                           Distributions qualify as tax-free distributions under
                           Section 355 of the Code.



<PAGE>


                                        8

                  (c)      Corning shall have received a favorable response from
                           the Commission to the "no-action request" letter
                           describing the Distributions filed by Corning with
                           the Commission.

                  (d)      The New York Stock Exchange shall have approved the
                           CCL Common Stock and Covance Common Stock for listing
                           on its exchange, subject to official notice of
                           distribution.

                  (e)      The financing arrangements among and between the
                           parties contemplated in the Information Statement
                           will have been consummated. CCL and Covance each
                           shall pay all of the expenses associated with their
                           respective financings.

                  SECTION 2.02. The Distributions and Other Transactions. (a)
Certain Transactions. Prior to the Distribution Date:

                  (i) CBI shall be merged with and into Covance pursuant to the
         Certificate of Ownership and Merger between CBI and Covance and the
         Certificate of Merger between CBI and Covance, in substantially the
         forms attached hereto as Exhibit C, and in accordance with all
         applicable filing requirements under the Delaware General Corporation
         Law and the New Jersey Business Corporation Act. As a result of the
         merger, CBI will cease to exist and Covance will acquire the assets of
         CBI and assume (or take the assets of CBI subject to) the liabilities
         of CBI.

                  (ii) CLSI will contribute to CCL all of CLSI's assets other
         than the stock of CCL and CLSI's rights under certain agreements that
         CLSI agrees to transfer pursuant to Section 2.02(i) in exchange for
         200,000 additional shares of CCL Common Stock and 1,000 shares of
         nonvoting preferred stock of CCL pursuant to (A) the Contribution
         Agreement between CLSI and CCL, (B) the Liabilities Undertaking between
         CLSI and CCL (C) the Instrument of Assignment and Assumption between
         CLSI and CCL and (D) the Bill of Sale and Assignment between CLSI and
         CCL, each in substantially the forms attached hereto as Exhibit A, and
         in accordance with all applicable filing requirements under the
         Delaware General Corporation Law. As a result of such transactions, CCL
         will acquire the assets of CLSI and assume (or take the assets of CLSI
         subject to) the liabilities of CLSI other than such obligations and
         liabilities for which either Corning or Covance is responsible under
         this Agreement or the Ancillary Agreements. Following such contribution
         and assumption, CLSI shall adopt a plan of liquidation and dissolve
         pursuant to the Plan of Liquidation and Dissolution of CLSI,
         substantially in the form attached hereto as Exhibit B, and in
         accordance with all applicable filing requirements under the Delaware
         General Corporation Law. As a result of such liquidation and
         dissolution, CLSI will distribute


<PAGE>


                                        9

         to Corning its remaining assets, which will consist largely of the
         capital stock of CCL, and CLSI will cease to exist.

                  (iii) No earlier than one day following the effective date for
         the transactions described in Section 2.02(a)(ii), CCL will transfer to
         certain of its subsidiaries the following shares of common stock that
         CCL will have received from CLSI pursuant to the transactions described
         in Section 2.02(a)(ii): (A) the shares of common stock of Corning
         Nichols Institute, (B) the shares of common stock of Corning Clinical
         Laboratories Inc. (Mass.) and (C) the shares of common stock of Corning
         Clinical Laboratories Inc. (MD).

                  (iv) No earlier than three (3) days following the later of the
         effective dates for the transactions described in Sections 2.02(a)(i),
         (ii) and (iii), CCL will transfer its Covance Common Stock, its entire
         interest in Pharmaceutical Laboratory Services, Inc. and its entire
         interest in Corning Bio Inc. to Covance by delivering to Covance stock
         certificates representing each of CCL's share interests in such
         companies, accompanied by stock powers duly endorsed by CCL and with
         all required stock transfer tax stamps affixed. In connection therewith
         CCL shall deliver to Covance for cancellation the share certificate
         currently held by it representing Covance Common Stock and Covance
         shall issue to CCL new certificates representing the total number of
         newly-issued shares of Covance Common Stock sufficient in number to
         allow for an orderly and pro rata distribution of such Covance Common
         Stock to the CCL common shareholders.

                  (v) No earlier than three (3) days following the later of the
         effective dates for the transactions described in Sections 2.02(a)(i),
         (ii) and (iii), Corning will transfer its CCL Common Stock and its
         entire interest in MRL Nucor, Inc. to CCL by delivering to CCL stock
         certificates representing each of Corning's share interests in CCL and
         MRL Nucor, Inc., accompanied by stock powers duly endorsed by Corning
         and with all required stock transfer tax stamps affixed. In connection
         therewith Corning shall deliver to CCL for cancellation the share
         certificate then held by it representing CCL Common Stock and shall
         receive new certificates representing the total number of newly-issued
         shares of CCL Common Stock sufficient in number to allow for an orderly
         and pro rata distribution of such CCL Common Stock to the Corning
         common shareholders.

                  (b) Ancillary Agreements. On or prior to the Distribution
Date, each of Corning, CCL and Covance shall have executed and delivered to each
of the others, each of the Ancillary Agreements.

                  (c) Charters; By-laws. On or prior to the Distribution Date:



<PAGE>


                                       10

                  (i) All necessary actions shall have been taken to provide for
         the amendments of the Articles of Incorporation and By-laws for CCL,
         such amendments to be in substantially the forms attached hereto as
         Exhibit H.

                  (ii) All necessary actions shall have been taken to provide
         for the amendments of the Articles of Incorporation and By-laws for
         Covance, such amendments to be in substantially the forms attached
         hereto as Exhibit I.

                  (d) Benefit Plans. On or prior to the Distribution Date, any
shareholder approvals deemed necessary for employee benefit plans shall have
been obtained.

                  (e) Directors. On or prior to the Distribution Date, Corning
as the sole shareholder of CCL, and CCL, as the sole shareholder of Covance,
shall have taken all necessary action by written consent on or prior to the
Distribution Date to elect to the Board of Directors of CCL and the Board of
Directors of Covance the individuals identified in the Information Statement as
directors of CCL and Covance, respectively.

                  (f) Consents. The parties hereto shall use their commercially
reasonable efforts to obtain any required consents to assignment of agreements
hereunder, if applicable.

                  (g) Delivery of Shares to Agent. Corning shall deliver to
Harris Trust and Savings Bank (the "Agent") the share certificates representing
the CCL Common Stock and CCL shall deliver to the Agent the share certificates
representing the Covance Common Stock and Corning and CCL shall instruct the
Agent to distribute, on or as soon as practicable following the Distribution
Date, such common stock to the Corning Record Holders and the CCL Record
Holders, as the case may be, as further contemplated by the Information
Statement and herein. CCL and Covance shall provide all share certificates that
the Agent shall require in order to effect the Distributions.

                  (h) Sublease. Corning shall have entered into a sublease
agreement with National Imaging Associates, Inc. with respect to the first floor
of 10 Mountainview Road, Upper Saddle River, New Jersey.

                  (i) Transfer of Agreements. (i) CLSI hereby agrees that on or
prior to the date on which it is dissolved, subject to the limitations set forth
in this Section 2.02(i), it will assign, transfer and convey to Covance all of
CLSI's rights and obligations under (a) the Capital Contribution Agreement and
Shareholder Agreement dated February 22, 1995 among Corning BioPro Inc., CLSI,
Richard Hawkins, Dr. John Scarlett, Robert F. Amundsen and Dr. Nona Niland, (b)
any and all existing stock option agreements between CLSI, Corning Bio Inc. and
individual employees of Corning Bio Inc., (c) the Registration Agreement dated
as of February 22, 1995 by and between Corning BioPro Inc. and CLSI, (d) the
Joint Escrow Instructions dated February 22, 1995 by and between Corning BioPro
Inc., CLSI,


<PAGE>


                                       11

Robert F. Amundsen and the Escrow Agent named therein, and (e) the Joint Escrow
Instructions dated February 22, 1995 by and between Corning BioPro Inc., CLSI,
Dr. John Scarlett and the Escrow Agent named therein. CLSI hereby further agrees
that on or prior to the date on which it is dissolved, subject to the
limitations set forth in this Section 2.02(i), it will assign, transfer and
convey to Corning all of its rights and obligations under the lease agreement
dated October 5, 1995 between 2154 Trading Corporation and CLSI with respect to
10 Mountainview Road, Upper Saddle River, New Jersey. CCL hereby agrees that on
or prior to the Distribution Date or as soon as reasonably practicable
thereafter, subject to the limitations set forth in this Section 2.02(i), it
will assign, transfer and convey to Corning all of CCL's rights and obligations
under the Asset Transfer Agreement dated as of May 2, 1994, as amended, among
CCL, International Technology Corporation, IT Corporation and Quanterra
Incorporated and the related closing documents thereunder, including without
limitation the General Instrument of Assignment and Assumption dated June 28,
1994 between CCL and Quanterra Incorporated. Corning hereby agrees that on or
prior to the Distribution Date or as soon as reasonably practicable thereafter,
subject to the limitations set forth in this Section 2.02(j), it will assign,
transfer and convey to Covance all of Corning's rights and obligations under
that certain Registration Agreement dated as of February 22, 1995 by and between
Corning, Dr. Nona Niland, Dr. John Scarlett, Robert F. Amundsen and Richard
Hawkins.

                  (ii) The assignee of any agreement assigned, in whole or in
part, hereunder (an "Assignee") shall assume and agree to pay, perform, and
fully discharge all obligations of the assignor under such agreement or such
Assignee's related portion of such obligations as determined in accordance with
the terms of the relevant agreement, where determinable on the face thereof, and
otherwise as determined in accordance with the practice of the parties prior to
the Distribution.

                  (iii) Notwithstanding anything in this Agreement to the
contrary, this Agreement shall not constitute an agreement to assign any
agreement, in whole or in part, or any rights thereunder if the agreement to
assign or attempt to assign, without the consent of a third party, would
constitute a breach thereof or in any way adversely affect the rights of the
Assignee thereof. Until such consent is obtained, or if an attempted assignment
thereof would be ineffective or would adversely affect the rights of any party
hereto so that the Assignee would not, in fact, receive all such rights, the
parties will cooperate with each other in any arrangement designed to provide
for the Assignee the benefits of, and to permit the Assignee to assume
liabilities under, any such agreement.

                  (iv) Corning understands and agrees that approximately 10,968
Corning Common Shares are held to secure certain claims of CCL under that Escrow
Agreement dated as of October 9, 1994 (the "Escrow Agreement") among Corning,
The First National Bank of Boston and former shareholders of Moran Research
Labs, as amended, and will act at CCL's direction and at CCL's expense with
respect to those shares. The remaining


<PAGE>


                                       12

Corning Common Shares held under the Escrow Agreement are being held for the
benefit of Corning.

                  (j) Other Transactions. On or prior to the Distribution Date,
each of Corning, CCL and Covance shall have consummated those other transactions
in connection with the Distributions that are contemplated by the Information
Statement and the ruling request submission by Corning to the Internal Revenue
Service dated June 17, 1996, as supplemented, and not specifically referred to
in subparagraphs (a)-(i) above.

                  SECTION 2.03. Treatment of Fractional Shares. As soon as
practicable after the Distribution Date, the Agent shall determine the number of
whole shares and fractional shares of CCL and Covance allocable to each Corning
Record Holder and CCL Record Holder, respectively, as of the Distribution Record
Date, to aggregate all such fractional shares and sell the whole shares obtained
thereby, in open market transactions or otherwise, in each case at then
prevailing trading prices, and to cause to be distributed to each such holder to
which a fractional share shall be allocable such holder's ratable share of the
proceeds of such sale, after making appropriate deductions of the amount
required to be withheld for federal income tax purposes and after deducting an
amount equal to all brokerage charges, commissions and transfer taxes attributed
to such sale. In determining the manner and timing of selling the aggregated
fractional shares, the Agent shall use its independent judgment and shall
neither consult with nor communicate its plans to Corning, CCL or Covance.

                  SECTION 2.04. Certain Intercompany Financial and Other
Arrangements. (a) Intercompany Accounts. Without limiting the terms of Section
2.05, all intercompany receivables, payables and loans (other than receivables,
payables and loans otherwise specifically provided for in any of the Ancillary
Agreements or hereunder), including, without limitation, in respect of any cash
balances, any cash balances representing deposited checks or drafts for which
only a provisional credit has been allowed or any cash held in any centralized
cash management system, between Corning, CCL, Covance or any of their respective
Subsidiaries, on the one hand, and Corning, CCL, Covance or any of their
respective Subsidiaries, on the other hand, shall, as of the Effective Time, be
settled, contributed to capital or converted into ordinary trade accounts, in
each case as may be agreed in writing prior to the Effective Time by duly
authorized representatives of Corning, CCL or Covance, as applicable.

                  (b) Operations in Ordinary Course. Each of CCL and Covance
covenants and agrees that, except as otherwise provided in any Ancillary
Agreement, during the period from the date of this Agreement through the
Distribution Date, it will, and will cause any entity that is a Subsidiary of
such party at any time during such period to, conduct its business in a manner
substantially consistent with current and past operating practices and in the
ordinary course, including, without limitation, with respect to the payment and


<PAGE>


                                       13

administration of accounts payable and the administration of accounts
receivable, the purchase of capital assets and equipment and the management of
inventories.

                  SECTION 2.05. Certain Indebtedness and Capital Structure.
Corning, CCL and Covance each agree to use their respective commercially
reasonable efforts to achieve both an allocation of consolidated indebtedness of
Corning and a capital structure (including cash position) of each of CCL and
Covance so as to substantially reflect the respective capital structures after
the Distributions of CCL and Covance set forth in the Information Statement
under the headings "Capitalization of CCL" and "Capitalization of Covance".

                  SECTION 2.06. Further Assurances. In case at any time after
the Effective Time any further action is reasonably necessary or desirable to
carry out the purposes of this Agreement and the Ancillary Agreements, the
proper officers of each party to this Agreement shall take all such necessary
action. Without limiting the foregoing, Corning, CCL and Covance shall use their
commercially reasonable efforts to obtain all consents and approvals, to enter
into all amendatory agreements and to make all filings and applications that may
be required for the consummation of the transactions contemplated by this
Agreement and the Ancillary Agreements, including, without limitation, all
applicable governmental and regulatory filings.

                  SECTION 2.07. No Representations or Warranties. Each of the
parties hereto understands and agrees that, except as otherwise expressly
provided, no party hereto is, in this Agreement, in any Ancillary Agreement or
in any other agreement or document contemplated by this Agreement or otherwise,
making any representation or warranty whatsoever, including, without limitation,
as to title, value or legal sufficiency.

                  SECTION 2.08. Guarantees. (a) Except as otherwise specified in
any Ancillary Agreement, Corning, CCL and Covance shall use their commercially
reasonable efforts to have, on or prior to the Distribution Date, or as soon as
practicable thereafter, Corning and any of its Subsidiaries removed as guarantor
of or obligor for any CCL Liability or Covance Liability, including, without
limitation, in respect of those guarantees set forth on Schedule 2.08(a), and to
the extent any such guarantee is not removed, CCL or Covance, as the case may
be, will indemnify Corning for all Indemnifiable Losses related to or arising
from such guarantee, in accordance with the procedures set forth in Section 3.05
and will pay Corning a fee reflecting Corning's continuing role as guarantor.

                  (b) Except as otherwise specified in any Ancillary Agreement,
Corning, CCL and Covance shall use their commercially reasonable efforts to
have, on or prior to the Distribution Date, or as soon as practicable
thereafter, CCL and any of its Subsidiaries removed as guarantor of or obligor
for any Corning Liability or Covance Liability, including, without limitation,
in respect of those guarantees set forth on Schedule 2.08(b), and to the extent
any such guarantee is not removed, Corning or Covance, as the case may


<PAGE>


                                       14

be, will indemnify CCL for all Indemnifiable Losses related to or arising from
such guarantee, in accordance with the procedures set forth in Section 3.05 and
will pay CCL a fee reflecting CCL's continuing role as guarantor.

                  (c) Except as otherwise specified in any Ancillary Agreement,
Corning, CCL and Covance shall use their commercially reasonable efforts to
have, on or prior to the Distribution Date, or as soon as practicable
thereafter, Covance and any of its Subsidiaries removed as guarantor of or
obligor for any Corning Liability or CCL Liability, including, without
limitation, in respect of those guarantees set forth on Schedule 2.08(c), and to
the extent any such guarantee is not removed, Corning or CCL, as the case may
be, will indemnify Covance for all Indemnifiable Losses related to or arising
from such guarantee, in accordance with the procedures set forth in Section 3.05
and will pay Covance a fee reflecting Covance's continuing role as guarantor.

                  SECTION 2.09. Certain Transactions. (a) On or prior to the
Distribution Date, and in accordance to Section 2.02(b), Corning, CCL and
Covance shall enter into (i) the Tax Sharing Agreement which shall govern, among
other things, their respective rights and obligations with respect to Taxes of
CCL and Covance and each of their respective Subsidiaries for all periods
through the Distribution Date and certain other tax-related matters; and (ii)
the Spin-off Tax Indemnification Agreements which shall, among other things,
restrict CCL and Covance from engaging in certain activities that might
jeopardize the continuing tax-free treatment of the Distributions.

                  (b) Following the Distribution Date, Corning, CCL and Covance
shall each comply with and otherwise not take any action inconsistent with each
representation and statement made, or to be made, to the Commission in
connection with the "no-action request" letter describing the Distributions
filed by Corning with the Commission.

                  SECTION 2.10. Insurance. Except as contemplated by the
Insurance Agreement, any and all coverage of CCL, Covance and their respective
Subsidiaries under Company Policies has terminated or will terminate (and will
not be replaced by Corning) no later than the Effective Time.


                                   ARTICLE III
                                 INDEMNIFICATION

                  SECTION 3.01. Indemnification by Corning. (a) Except as
otherwise specifically set forth in any provision of this Agreement or of any
Ancillary Agreement, Corning shall indemnify and hold harmless the CCL
Indemnitees and the Covance Indemnitees from and against any and all
Indemnifiable Losses of the CCL Indemnitees and the Covance Indemnitees,
respectively, arising out of, by reason of or otherwise in


<PAGE>


                                       15

connection with (i) the Corning Liabilities or (ii) the breach by Corning of any
provision of this Agreement or any Ancillary Agreement.

                  (b) Corning shall indemnify and hold harmless CCL and its
Subsidiaries from and against any and all monetary payments by CCL or its
Subsidiaries (other than criminal fines or penalties imposed upon former or
current employees of CCL or its subsidiaries) to the United States government or
one of the States of the United States or any of their respective departments,
branches or agencies arising out of any investigation or claim by or on behalf
of the United States government or one of the States of the United States or any
of their respective departments, branches or agencies, whether criminal, civil
or administrative in nature which investigation or claim has been settled prior
to the Distribution Date or is pending as of the Distribution Date pursuant to
service of subpoena or other notice of such investigation to CCL or its
Subsidiaries, as well as any qui tam proceeding for which a complaint was filed
prior to the Distribution Date whether or not CCL or any Subsidiary of CCL has
been served with such complaint or otherwise been notified of the pendency of
such action, but only to the extent such investigations or claims arise out of
or are related to alleged violations of (i) the federal civil False Claims Act
(31 USC ss. 3729, et seq.) and its criminal counterpart (18 USC ss. 287), (ii)
Medicare and Medicaid fraud (42 USC ss. 1320a-7(b)(a)(1)), (iii) the Civil
Monetary Penalties Law (42 USC ss.ss. 1320a-7a and 1320a-7(b)(b)), (iv) mail
fraud and wire fraud statutes (18 USC ss.ss. 1341 and 1343), (v) false
statements (18 USC ss. 1301), (vi) conspiracy (18 USC ss. 371), (vii) money
laundering (18 USC ss. 1956, et seq.), (viii) RICO (18 USC ss. 1961), (ix) Title
II of the Health Insurance Portability and Accountability Act of 1996, (x) Title
XVIII of the Social Security Act (42 USC ss.ss. 1395- 1395ccc) (the Medicare
statute), (xi) Title XIX of the Social Security Act (42 USC ss.ss. 1396, et
seq.) (the Medicaid statute), (xii) the Programs Fraud Civil Remedies Act (31
USC ss.ss. 3801, et seq.); or (xiii) the federal Anti-Kickback Act (42 USC
ss.ss. 52, et seq.) by reason of the billing or alleged overbilling by CCL or
any past or present subsidiary of CLSI (or any of their predecessors) of any
federal program or agency, or any federally supported state health care program
or agency, or any beneficiary of any of them, for services provided to any such
beneficiary thereof by CCL, any Subsidiary of CCL or any past or present
subsidiary of CLSI (or any of their predecessors).

                  (c) In the event that CCL or its Subsidiaries make monetary
payments in excess of forty-two million dollars ($42,000,000) within the period
beginning on the Distribution Date and ending five (5) years thereafter in
respect of claims by nongovernmental persons actually relating to or arising out
of the investigations or claims referred to in Section 3.01(b) and alleging
overbillings of such person or any beneficiary of such person by CCL, its
Subsidiaries or any past or present subsidiary of CLSI (or any of their
predecessors) for services provided prior to the Distribution Date to such
person or beneficiary thereof by CCL, its Subsidiaries or any past or present
subsidiary of CLSI (or any of their predecessors), then Corning shall indemnify
and hold harmless CCL and its Subsidiaries from and against fifty percent (50%)
of up to fifty million dollars ($50,000,000)


<PAGE>


                                       16

in the aggregate of such monetary payments actually paid by CCL or any
Subsidiary of CCL in excess of such forty-two million dollars ($42,000,000) in
respect of such alleged overbillings.

         (d) (i) All payments made by Corning to CCL, or to another party for
the benefit of CCL, pursuant to Section 3.01(b) and (c) shall be treated as
nontaxable capital contributions by Corning to CCL and the parties shall report
the payments consistent with such treatment for Tax purposes.

         (ii) Each amount indemnified against by Corning pursuant to Section
3.01(b) and Section 3.01(c) shall reduced by (1) the product of (x) the amount
of any Tax deduction realized by CCL, any CCL Subsidiary (CCL and the CCL
Subsidiaries shall be referred to in this Section 3.01(d) as the "CCL
Companies") or any combined or consolidated group which has as a member any of
the CCL Companies (the "CCL Group") attributable to the payment or accrual of
the underlying obligation indemnified against by Corning and (y) the maximum
marginal statutory rate at which the Tax to which such deduction relates is
imposed for the taxable year in which the underlying obligation indemnified
against by Corning is paid, and (2) the amount of any other Tax credit, benefit
or other similar item (a "Tax Benefit Item") realized by any CCL Company or the
CCL Group as a result of the payment or accrual of the underlying obligation
indemnified against by Corning.

         (iii) For purposes of Section 3.01(d)(ii), a Tax deduction or Tax
Benefit Item resulting from an amount indemnified against is realized when the
calculation of any Tax of any CCL Company or the CCL Group, taking into account
the Tax deduction or Tax Benefit Item, for a Tax year is less than the
calculation of such Tax without taking such deduction or item into account
assuming, in both cases, such Tax were calculated without regard to (1) any
carryover to such year of losses, Tax deductions or Tax Benefit Items of any CCL
Company or the CCL Group, except as provided in Section 3.01(d)(vi), and (2) any
Tax deductions or Tax Benefit Items of any CCL Company or the CCL Group in
respect of any payments described in Section 3.01(b) or Section 3.01(c) that are
not indemnified against by Corning (including, without limitation, monetary
payments up to $42,000,000 which are applied towards the threshold in Section
3.01(c)).

         (iv) Corning shall make estimated payments to CCL, or another party for
the benefit of CCL, pursuant to Section 3.01(b) and Section 3.01(c) (the
"Estimated Payments") which shall be calculated by Corning in accordance with
Section 3.02(d)(ii) and without reference to the ordering rules of Section
3.01(d)(iii). Estimated Payments shall be paid by Corning (1) if paid to a CCL
Company, as directed by CCL, within 30 days after written notice from CCL to
Corning indicating that the underlying obligation indemnified against by Corning
has been paid by a CCL Company (which notice shall include any documentation
reasonably requested by Corning establishing the amount and Tax treatment of
such payment) or, (2) if paid directly by Corning for the benefit of a CCL
Company, within 30 days after


<PAGE>


                                       17

written notice from CCL that the obligation has been settled (which notice shall
include to whom such payment should be made, the amount of the settlement, an
executed copy of the settlement or other agreement and any other documentation
reasonably requested by Corning establishing the amount and Tax treatment of
such settlement). Within 90 days following the close of the Tax year in which an
Estimated Payment is made, CCL and Corning shall recompute the amount
indemnified against under Section 3.01(d)(ii) and 3.01(d)(iii) and shall make
any adjusting payment to each other resulting from such recomputation within 30
days of their agreement as to the amount of such adjusting payment.

         (v) CCL shall consult with Corning and CCL and Corning shall determine
the Tax treatment by any CCL Company or the CCL Group of any obligation or
payment which is indemnified against by Corning under Section 3.01(b) or Section
3.01(c). The parties shall report the payments consistent with the treatment as
determined for Tax purposes.

         (vi) If any payments are made by Corning pursuant to Section 3.01(b) or
Section 3.01(c), and calculated and paid pursuant to this Section 3.01(d), and
the amount payable by Corning pursuant to such sections could have been reduced
if the computation of such indemnification payment were made at a later time
(through the utilization in a subsequent Tax year of Tax deductions or Tax
Benefit Items by any CCL Company or the CCL Group relating to settlement
payments or other amounts indemnified against by Corning but not previously
recognized because of the ordering rules in 3.01(d)(iii) or otherwise), then the
amount of such indemnification shall be recomputed by CCL at such later time by
taking into account and carrying over such previously utilized Tax deductions or
Tax Benefit Items. The amount of reduction, if any, resulting from such
recomputation shall be calculated within 60 days of the filing of any Tax return
by any CCL Company or the CCL Group for the Tax year that causes the
computation. Any amount by which the amount previously paid would be reduced
pursuant to this Section 3.01(d)(vi) shall be paid to Corning within 30 days of
such recomputation together with interest (computed at the rate or rates at
which interest on underpayments of tax is payable to the Internal Revenue
Service under the relevant provisions of the Code in effect for such period)
from the date the Tax return of the CCL Company or the CCL Group, as the case
may be, was due (without extension) for the Tax year giving rise to the
recomputation to the date of payment to Corning.

         (vii) Promptly after receipt by any CCL Company of notice of any
demand, claim or circumstances relating to the Tax treatment of an obligation or
payment which gave rise to an indemnification obligation by Corning under
Section 3.01(b) or Section 3.01(c), CCL shall give notice thereof to Corning.
Such notice shall contain factual information (to the extent known to any CCL
Company) describing the asserted tax treatment in reasonable detail and shall
include copies of any notice or other document received from any taxing
authority. At its election, Corning shall control the prosecution and
disposition (through settlement or otherwise) of any audits and any contests in
respect of any claim made by a taxing authority on audit or in a related
administrative or judicial proceeding or in respect of

<PAGE>


                                       18

any refund or credit of taxes, that relates to the tax treatment by any CCL
Company of an obligation or payment which gives rise to an indemnification
obligation by Corning under Section 3.01(b) or Section 3.01(c) or the Tax
treatment of an item determined under Section 3.01(d)(v). CCL may participate in
such audits or contests at CCL's expense to the extent that Corning in its
reasonable discretion shall deem appropriate. If asserted liabilities unrelated
to the matters contemplated herein become grouped with contests arising
hereunder, the parties shall use their respective best efforts to cause the
contest arising hereunder to be the subject of a separate proceeding. With
respect to matters arising hereunder controlled by Corning, and where deemed
necessary by Corning, CCL shall itself, and shall compel any CCL Subsidiary to,
authorize by appropriate powers of attorney such persons as Corning shall
designate to represent CCL, or such CCL Subsidiary, with respect to such
matters. Corning, in its sole discretion, shall have the power to settle,
compromise, or concede such adjustment or claim without prior written notice to
or approval of CCL and any Subsidiary of CCL. If, as a result of the settlement
of or other final decision (which Corning cannot legally or determines in its
sole discretion not to contest) with respect to any audits, contests,
administrative or judicial proceedings described herein, the amount of any
payments made by Corning pursuant to Section 3.01(b) or Section 3.01(c), and
calculated and paid pursuant to this Section 3.01(d), is different from the
amount which would be paid taking into account such settlement of or other final
decision, CCL and Corning shall recompute the amount indemnified against under
this Section 3.01(d) and shall make any adjusting payment to each other
resulting from such recomputation within 30 days of their agreement as to the
amount of such adjusting payment.

         (viii) If Corning and CCL are unable to agree on the proper calculation
or treatment of a payment or other obligation, a Tax deduction or Tax Benefit
Item or any other item described in this Section 3.01(d), then such disputed
item or items shall be resolved by a nationally recognized accounting or law
firm chosen and mutually acceptable to both parties. Such accounting or law firm
shall resolve the dispute within 30 days of having the item or items referred to
it and such resolution shall be binding on the parties. The costs, fees and
expenses of the accounting or law firm shall be borne equally by Corning and
CCL. In the event the parties are not able to agree on an accounting or law
firm, each party shall select its own nationally recognized law firm (and bear
the costs, fees and expenses thereof) and such law firms shall select a
nationally recognized accounting or law firm which accounting or law firm shall
be deemed to be mutually acceptable to both parties for the purpose of applying
this provision.

                  (e) Notwithstanding anything to the contrary in this
agreement, Corning shall not indemnify, defend or hold harmless CCL or any
Subsidiary of CCL against (x) costs and expenses relating to the investigations
or claims referred to in Sections 3.01(b) and (c) (including, without
limitation, fees and expenses of attorneys, consultants and other agents of CCL
or any Subsidiary of CCL), or (y) losses of revenues or profits that may arise
as a consequence of the claims or investigations referred to in Sections 3.01(b)
or 3.01(c) or


<PAGE>


                                       19

the settlements entered into or judgments rendered as a result thereof or as a
consequence of any exclusion from participation in any federal or state health
care program, or (z) any other consequential or incidental damages that may be
incurred by CCL or any Subsidiary of CCL, in each case which relates to the
billing of any person or any beneficiary of such person by CCL, any Subsidiary
of CCL or any past or present subsidiary of CLSI (or any of their predecessors)
for services provided to any such person or beneficiary thereof by CCL, any
Subsidiary of CCL or any past or present subsidiary of CLSI (or any of their
predecessors).

                  (f) All indemnification obligations of Corning pursuant to
this Section 3.01 may be made or assumed by an Affiliate of Corning to the
extent deemed necessary or desirable by Corning in its sole discretion.

                  SECTION 3.02. Indemnification by CCL. Except as otherwise
specifically set forth in any provision of this Agreement or of any Ancillary
Agreement, CCL shall indemnify and hold harmless the Corning Indemnitees and the
Covance Indemnitees from and against any and all Indemnifiable Losses of the
Corning Indemnitees and the Covance Indemnitees, respectively, arising out of,
by reason of or otherwise in connection with (i) the CCL Liabilities or (ii) the
breach by CCL of any provision of this Agreement or any Ancillary Agreement;
provided, however, that CCL is under no obligation to indemnify or hold harmless
Corning from and against any Indemnifiable Losses arising out of, or by reason
of or otherwise in connection with any and all monetary payments by Corning 
in respect of the investigations or claims referred to in Section 3.01(b).

                  SECTION 3.03. Indemnification by Covance. Except as otherwise
specifically set forth in any provision of this Agreement or of any Ancillary
Agreement, Covance shall indemnify and hold harmless the Corning Indemnitees and
the CCL Indemnitees from and against any and all Indemnifiable Losses of the
Corning Indemnities and the CCL Indemnitees, respectively, arising out of, by
reason of or otherwise in connection with (i) the Covance Liabilities or (ii)
the breach by Covance of any provision of this Agreement or any Ancillary
Agreement.

                  SECTION 3.04. Adjustments for Indemnification Obligations. If
the amount that any party (an "Indemnifying Party") is or may be required to pay
to any other person (an "Indemnitee") pursuant to Section 3.01, Section 3.02 or
Section 3.03, as applicable, shall, at any time subsequent to the payment
required by this Agreement, be reduced by insurance or other recovery,
settlement or otherwise, the amount of such reduction, less any expenses
incurred in connection therewith, shall promptly be repaid by the Indemnitee to
the Indemnifying Party, up to the aggregate amount of any payments received from
such Indemnifying Party pursuant to this Agreement in respect of such
Indemnifiable Loss.

                  SECTION 3.05. Procedures for Indemnification - Third Party
Claims. If a claim or demand is made against an Indemnitee by any person who is
not a party to this Agreement (a "Third Party Claim") as to which such
Indemnitee is entitled to indemnification pursuant to this Agreement, such
Indemnitee shall notify the Indemnifying Party in writing, and in reasonable
detail, of the Third Party Claim promptly (and in any


<PAGE>


                                       20

event within 15 business days) after receipt by such Indemnitee of written
notice of the Third Party Claim; provided, however, that failure to give such
notification shall not affect the indemnification provided hereunder except to
the extent the Indemnifying Party shall have been actually prejudiced as a
result of such failure (except that the Indemnifying Party shall not be liable
for any expenses incurred during the period in which the Indemnitee failed to
give such notice).

                  If a Third Party Claim is made against an Indemnitee, the
Indemnifying Party shall be entitled to participate in the defense thereof and,
in the case of an Indemnifying Party's obligation to indemnify the Indemnitee
pursuant to Section 3.01(a), Section 3.01(b), Section 3.02 or Section 3.03, if
the Indemnifying Party so chooses and acknowledges in writing its obligation to
indemnify the Indemnitee therefor, to assume the defense thereof with counsel
selected by the Indemnifying Party; provided, however, that such counsel is not
reasonably objected to by the Indemnitee. Should the Indemnifying Party so elect
to assume the defense of a Third Party Claim, the Indemnifying Party shall not
be liable to the Indemnitee for legal or other expenses subsequently incurred by
the Indemnitee in connection with the defense thereof. If the Indemnifying Party
assumes such defense, the Indemnitee shall have the right to participate in the
defense thereof and to employ counsel, at its own expense, separate from the
counsel employed by the Indemnifying Party, it being understood that the
Indemnifying Party shall control such defense. The Indemnifying Party shall be
liable for the fees and expenses of counsel employed by the Indemnitee for any
period during which the Indemnifying Party has failed to assume the defense
thereof. If the Indemnifying Party so elects to assume the defense of any Third
Party Claim, all of the Indemnitees shall cooperate with the Indemnifying Party
in the defense or prosecution thereof.

                  If the Indemnifying Party acknowledges in writing liability
for a Third Party Claim, then in no event will the Indemnitee admit any
liability with respect to, or settle, compromise or discharge, any Third Party
Claim without the Indemnifying Party's prior written consent; provided, however,
that the Indemnitee shall have the right to settle, compromise or discharge such
Third Party Claim without the consent of the Indemnifying Party if the
Indemnitee releases the Indemnifying Party from its indemnification obligation
hereunder with respect to such Third Party Claim and such settlement, compromise
or discharge would not otherwise adversely affect the Indemnifying Party. If the
Indemnifying Party acknowledges in writing liability for a Third Party Claim,
the Indemnitee will agree to any settlement, compromise or discharge of a Third
Party Claim that the Indemnifying Party may recommend which by its terms (i)
obligates the Indemnifying Party to pay the full amount of its indemnification
obligation in connection with such Third Party Claim and (ii) releases the
Indemnitee completely in connection with such Third Party Claim and which would
not otherwise adversely affect the Indemnitee; and provided further that the
Indemnitee may refuse to agree to any such proposed settlement, compromise or
discharge if the Indemnitee agrees that the Indemnifying Party's indemnification
obligation with respect to such Third Party Claim shall not exceed the amount
that would be required to be paid by or


<PAGE>


                                       21

on behalf of the Indemnifying Party in connection with such proposed settlement,
compromise or discharge.

                  Notwithstanding the foregoing, the Indemnifying Party shall
not be entitled to assume the defense of any Third Party Claim (and shall be
liable for the fees and expenses of counsel incurred by the Indemnitee in
defending such Third Party Claim) if the Third Party Claim seeks an order,
injunction or other equitable relief or relief for other than money damages
against the Indemnitee which the Indemnitee reasonably determines, after
conferring with its counsel, cannot be separated from any related claim for
money damages. If such equitable relief or other relief portion of the Third
Party Claim can be so separated from that for money damages, the Indemnifying
Party shall be entitled to assume the defense of the portion relating to money
damages.

                  The provisions contained in Section 3.01(d) shall control in
the situations described particularly in that section.

                  SECTION 3.06. Survival of Indemnities. The obligations of
Corning, CCL and Covance under this Article III shall survive the sale or other
transfer by any of them of any assets or businesses, with respect to any
Indemnifiable Loss of any Indemnitee related to such assets or businesses.

                  SECTION 3.07. Payments. All payments under this Agreement
shall be made without gross-up for Taxes.


                                   ARTICLE IV
                              ACCESS TO INFORMATION

                  SECTION 4.01. Provision of Corporate Records. From and after
the Distribution Date, upon the prior written request by Corning, CCL or Covance
for specific and identified agreements, documents, books, records or files
(collectively, "Records") relating to or affecting Corning, CCL or Covance, as
applicable, Corning, CCL or Covance, as the case may be, shall arrange, as soon
as reasonably practicable following the receipt of such request, for the
provision of appropriate copies of such Records (or other originals thereof if
the party making the request has a reasonable need for such originals) then in
the possession of Corning, CCL or Covance, as the case may be, or any of their
Subsidiaries, but only to the extent such items are not already in the
possession of the requesting party; provided, however, that nothing in this
Section 4.01 shall obligate a party to retain any records except to the extent
required by law or by an Ancillary Agreement or to provide Records if the party
reasonably determines that such provision of Records would prevent it from
claiming that the Records were privileged or otherwise not subject to disclosure
in any Action.


<PAGE>


                                       22


                  SECTION 4.02. Access to Information. (a) From and after the
Distribution Date, each of Corning, CCL and Covance shall afford to the other
and its authorized accountants, counsel and other designated representatives
reasonable access during normal business hours, subject to appropriate
restrictions for classified, privileged or confidential information, to the
personnel, properties, books and records of such party and its Subsidiaries
insofar as such access is reasonably required by the other party.

                  (b) For a period of five years following the Distribution
Date, each of Corning, CCL and Covance shall provide to the other, promptly
following such time at which such documents shall be filed with the Commission,
all documents that shall be filed by it and by any of its respective
Subsidiaries with the Commission pursuant to the periodic and interim reporting
requirements of the Exchange Act, and the rules and regulations of the
Commission promulgated thereunder.

                  SECTION 4.03. Reimbursement. Except to the extent otherwise
contemplated by any Ancillary Agreement, a party providing Records or access to
information to the other party under this Article IV shall be entitled to
receive from the recipient, upon the presentation of invoices therefor, payments
for such amounts, relating to supplies, disbursement and other out-of-pocket
expenses, as may be reasonably incurred in providing such Records or access to
information.

                  SECTION 4.04. Confidentiality. (a) Each of (i) Corning and its
Subsidiaries, (ii) CCL and its Subsidiaries and (iii) Covance and its
Subsidiaries shall not use or permit the use of (without the prior written
consent of the other) and shall hold, and shall cause its directors, officers,
employees, agents, consultants and advisors to hold, in strict confidence, all
information concerning the other parties in its possession, its custody or under
its control (except to the extent that (x) such information has been in the
public domain through no fault of such party, (y) such information has been
later lawfully acquired from other sources by such party or (z) this Agreement,
any Ancillary Agreement or any other agreement entered into pursuant hereto
permits the use or disclosure of such information) to the extent such
information (i) was obtained prior to or relates to periods prior to the
Effective Time, (ii) relates to any Ancillary Agreement or (iii) is obtained in
the course of performing services for the other party pursuant to any Ancillary
Agreement, and each party shall not (without the prior written consent of the
other) otherwise release or disclose such information to any other person,
except such party's auditors and attorneys, unless compelled to disclose such
information by judicial or administrative process or unless such disclosure is
required by law and such party has used commercially reasonable efforts to
consult with the other affected party or parties prior to such disclosure.

                  (b) To the extent that a party hereto is compelled by judicial
or administrative process to disclose otherwise confidential information under
circumstances in which any evidentiary privilege would be available, such party
agrees to assert such privilege


<PAGE>


                                       23

in good faith prior to making such disclosure. Each of the parties hereto agrees
to consult with each relevant other party in connection with any such judicial
or administrative process, including, without limitation, in determining whether
any privilege is available, and further agrees to allow each such relevant party
and its counsel to participate in any hearing or other proceeding (including,
without limitations, any appeal of an initial order to disclose) in respect of
such disclosure and assertion of privilege.


                                    ARTICLE V
                               DISPUTE RESOLUTION

                  SECTION 5.01. Good Faith Negotiations. In the event of a
controversy, dispute or claim arising out of, in connection with, or in relation
to the interpretation, performance, nonperformance, validity or breach of this
Agreement or otherwise arising out of, or in any way related to this Agreement,
including, without limitation, any claim based on contract, tort or statute
(collectively, "Agreement Disputes"), the general counsels of the relevant
parties shall negotiate in good faith for a reasonable period of time to settle
such Agreement Dispute.

                  SECTION 5.02. Procedure. If after such reasonable period such
general counsels are unable to settle such Agreement Dispute (and in any event
after 60 days have elapsed from the time the relevant parties began such
negotiations), such Agreement Dispute shall be determined, at the request of any
relevant party, by arbitration conducted in New York City, before and in
accordance with the then-existing Rules for Commercial Arbitration of the
American Arbitration Association (the "Rules"), and any judgment or award
rendered by the arbitrator shall be final, binding and nonappealable (except
upon grounds specified in 9 U.S.C. ss. 10(a) as in effect on the date hereof),
and judgment may be entered by any state or federal court having jurisdiction
thereof in accordance with Section 6.16 hereof. Unless the arbitrator otherwise
determines, the pre-trial discovery of the then-existing Federal Rules of Civil
Procedure and the then-existing Rules 46 and 47 of the Civil Rules for the
United States District Court for the Southern District of New York shall apply
to any arbitration hereunder. Any controversy concerning whether an Agreement
Dispute is an arbitrable Agreement Dispute, whether arbitration has been waived,
whether an assignee of this Agreement is bound to arbitrate, or as to the
interpretation of enforceability of this Article V shall be determined by the
arbitrator. The arbitrator shall be a retired or former judge of any United
States District Court or Court of Appeals or such other qualified person as the
relevant parties may agree to designate, provided, however, such individual has
had substantial professional experience with regard to settling sophisticated
commercial disputes. The parties intend that the provisions to arbitrate set
forth herein be valid, enforceable and irrevocable. The designation of a situs
or a governing law for this Agreement or the arbitration shall not be deemed an
election to preclude application of the Federal Arbitration Act, if it would be
applicable. In his or her award the arbitrator shall allocate, in his or her


<PAGE>


                                       24

discretion, among the parties to the arbitration all costs of the arbitration,
including, without limitation, the fees and expenses of the arbitrator and
reasonable attorneys' fees, costs and expert witness expenses of the parties.
The undersigned agree to comply with any award made in any such arbitration
proceedings that has become final in accordance with the Rules and agree to the
entry of a judgment in any jurisdiction upon any award rendered in such
proceedings becoming final under the Rules. The arbitrator shall be entitled if
appropriate, to award any remedy in such proceedings, including, without
limitation, monetary damages, specific performance and all other forms of legal
and equitable relief; provided, however, the arbitrator shall not be entitled to
award punitive damages.


                                   ARTICLE VI
                               GENERAL PROVISIONS

                  SECTION 6.01. Expenses. Except as otherwise set forth in this
Agreement or any Ancillary Agreement, each of Corning, CCL and Covance shall
bear its own costs and expenses incurred on or prior to the Distribution Date
(whether or not paid on or prior to the Distribution Date) in connection with
the preparation, execution, delivery and implementation of this Agreement and
any Ancillary Agreement, the Information Statement, the Registration Statements
and the Distributions and the consummation of the transactions contemplated
thereby and the parties to this Agreement shall agree on an equitable allocation
of costs and expenses where any item is not clearly allocable to Corning, CCL or
Covance. Except as otherwise set forth in this Agreement or any Ancillary
Agreement, each party shall bear its own costs and expenses incurred after the
Distribution Date.

                  SECTION 6.02. Notices. All notices, requests, claims, demands
and other communications hereunder shall be in writing and shall be given or
made (and shall be deemed to have been duly given or made upon receipt) by
delivery in person, by courier service, by cable, by telecopy, by telegram, by
telex or by registered or certified mail (postage prepaid, return receipt
requested) to the respective parties at the addresses (or at such other address
for a party as shall be specified in a notice given in accordance with this
Section 6.02) listed below (with copies to Shearman & Sterling at 599 Lexington
Avenue, New York, New York 10022, Attn: Creighton Condon):

         (a)      To Corning Incorporated:

                  One Riverfront Plaza
                  Corning, New York  14831
                  Telecopy:  (607) 974-8656

                  Attn:  General Counsel



<PAGE>


                                       25

         (b)      To CCL:

                  One Malcolm Avenue
                  Teterboro, New Jersey  07608
                  Telecopy:  (201) 462-4795

                  Attn:  General Counsel

         (c)      To Covance:

                  210 Carnegie Center
                  Princeton, New Jersey  08540-6233
                  Telecopy:  (609) 452-9865

                  Attn:  General Counsel

                  SECTION 6.03. Complete Agreement; Construction. This
Agreement, including the Exhibits and Schedules, and the Ancillary Agreements
shall constitute the entire agreement between the parties hereto with respect to
the subject matter hereof and shall supersede all prior agreements and
undertakings, both written and oral, between the parties with respect to the
subject matter hereof and thereof. In the event of any inconsistency between
this Agreement and any Schedule hereto, the Schedule shall prevail.
Notwithstanding any other provisions in this Agreement to the contrary, in the
event and to the extent that there shall be a conflict between the provisions of
this Agreement and the provisions of any Ancillary Agreement, such Ancillary
Agreement shall control.

                  SECTION 6.04. Ancillary Agreements. This Agreement is not
intended to address, and should not be interpreted to address, the matters
specifically and expressly covered by the Ancillary Agreements.

                  SECTION 6.05. Counterparts. This Agreement may be executed in
one or more counterparts, and by the different parties hereto in separate
counterparts, each of which when executed shall be deemed to be an original but
all of which taken together shall constitute one and the same agreement.

                  SECTION 6.06. Survival of Agreements. Except as otherwise
contemplated by this Agreement, all covenants and agreements of the parties
contained in this Agreement shall survive the Distribution Date.

                  SECTION 6.07. Waiver. The parties to this Agreement may (a)
extend the time for the performance of any of the obligations or other acts of
the other party or parties, (b) waive any inaccuracies in the representations
and warranties of the other party or parties


<PAGE>


                                       26

contained herein or in any document delivered by the other party or parties
pursuant hereto or (c) waive compliance with any of the agreements or conditions
of the other party or parties contained herein. Any such extension or waiver
shall be valid only if set forth in an instrument in writing signed by the party
to be bound thereby. Any waiver of any term or condition shall not be construed
as a waiver of any subsequent breach or a subsequent waiver of the same term or
condition, or a waiver of any other term or condition, of this Agreement. The
failure of any party to assert any of its rights hereunder shall not constitute
a waiver of any such rights.

                  SECTION 6.08. Amendments. Subject to the terms of Section 6.11
hereof, this Agreement may not be amended or modified except (a) by an
instrument in writing signed by, or on behalf of, the parties or (b) by a waiver
in accordance with Section 6.07.

                  SECTION 6.09. Assignment. This Agreement may not be assigned
by operation of law or otherwise without the express written consent of the
other parties (which consent may be granted or withheld in the sole discretion
of the parties), and any attempt to assign any rights or obligations arising
under this Agreement without such consent shall be void.

                  SECTION 6.10. Successors and Assigns. The provisions of this
Agreement shall be binding upon, inure to the benefit of and be enforceable by
the parties and their respective successors and permitted assigns.

                  SECTION 6.11. Termination. This Agreement (including, without
limitation, Article III hereof) may be terminated and the Distributions may be
amended, modified or abandoned at any time prior to the Distributions by and in
the sole discretion of Corning without the approval of CCL or Covance or the
shareholders of Corning. In the event of such termination, no party shall have
any liability of any kind to any other party or any other person. After the
Distributions, this Agreement may not be terminated except by an agreement in
writing signed by the parties; provided, however, that Article III shall not be
terminated or amended after the Distributions in respect of the third party
beneficiaries thereto without the consent of such persons.

                  SECTION 6.12. Subsidiaries. Each of the parties hereto shall
cause to be performed, and hereby guarantees the performance of, all actions,
agreements and obligations set forth herein to be performed by any Subsidiary of
such party or by any entity that is contemplated to be a Subsidiary of such
party on and after the Distribution Date.

                  SECTION 6.13. Third Party Beneficiaries. Except as provided in
Article III relating to Indemnitees, this Agreement shall be binding upon and
inure solely to the benefit of the parties hereto and their respective
Subsidiaries, Affiliates and assigns and nothing herein, express or implied, is
intended to or shall confer upon any third parties any legal or


<PAGE>


                                       27

equitable right, benefit or remedy of any nature whatsoever under or by reason
of this Agreement.

                  SECTION 6.14. Headings. The descriptive headings contained in
this Agreement are for convenience of reference only and shall not affect in any
way the meaning or interpretation of this Agreement.

                  SECTION 6.15. Specific Performance. The parties hereto agree
that irreparable damage would occur in the event any provision of this Agreement
was not performed in accordance with the terms hereof and that the parties shall
be entitled to specific performance of the terms hereof, in addition to any
other remedy at law or equity.

                   SECTION 6.16. Governing Law. This Agreement shall be governed
by, and construed in accordance with, the laws of the State of New York,
applicable to contracts executed in and to be performed entirely within that
state. Without limiting the provisions of Article V, all actions and proceedings
arising out of or relating to this Agreement shall be heard and determined in
any New York state or federal court sitting in the City of New York.

                  SECTION 6.17. Public Announcements. (a) Prior to the Effective
Time, neither CCL nor Covance shall make, or cause to be made, any press release
or public announcement in respect of this Agreement or the transactions
contemplated hereby or otherwise communicate with any news media without the
prior written consent of Corning.

                  (b) Following the Effective Time, no party to this Agreement
shall make, or cause to be made, any press release or public announcement in
respect of this Agreement or the transactions contemplated hereby or otherwise
communicate with any news media without prior consultation with the other
parties, and the parties shall cooperate as to the timing and contents of any
such press release or public announcement.

                  SECTION 6.18. Severability. If any term or other provision of
this Agreement is invalid, illegal or incapable of being enforced by any law or
public policy, all other terms and provisions of this Agreement shall
nevertheless remain in full force and effect so long as the economic or legal
substance of the transactions contemplated hereby is not affected in any manner
materially adverse to any party. Upon such determination that any term or other
provision is invalid, illegal or incapable of being enforced, the parties hereto
shall negotiate in good faith to modify this Agreement so as to effect the
original intent of the parties as closely as possible in an acceptable manner in
order that the transactions contemplated hereby are consummated as originally
contemplated to the greatest extent possible.


<PAGE>


                                       28


                  IN WITNESS WHEREOF, the parties have caused this Agreement to
be executed as of the date first written above by their respective officers
thereunto duly authorized.


                                     CORNING INCORPORATED

                                     by________________________________________
                                      Name:
                                     Title:



                                     CORNING LIFE SCIENCES INC.

                                     by________________________________________
                                      Name:
                                     Title:



                                     CORNING CLINICAL LABORATORIES INC.


                                     by________________________________________
                                      Name:
                                     Title:



                                     COVANCE INC.


                                     by________________________________________
                                      Name:
                                     Title:


                                                                      Exhibit A
                      RESTATED CERTIFICATE OF INCORPORATION
                                       OF
                                  COVANCE INC.

1.   Name. The name of the Corporation is Covance Inc.

2.   Address. The address of the Corporation's registered office in the State of
Delaware is 1209 Orange Street, in the City of Wilmington, County of New Castle.
The  name of the  Registered  Agent at such  address  is the  Corporation  Trust
Company.

3.   Corporate  Purpose.  The  purpose  of the  Corporation  is  (i) to own  and
operate,  clinical,  industrial  and  research  laboratories,  (ii)  to  provide
contract   biopharmaceutical   development   services  and  (iii)  to  research,
manufacture design,  construct, use, buy, sell, lease, hire and deal in and with
articles and property of all kinds,  to render  services of all kinds,  and (iv)
generally to engage in any lawful act or activity for which  corporations may be
organized under the General Corporation Law of Delaware.

4.   Capitalization.  The  total  number of shares  which  the  Corporation  may
henceforth have is  150,000,000,  of which  10,000,000  shares are to have a par
value of $1.00 each and 140,000,000 shares are to have a par value of $.01 each,
which shares shall be classified as follows:

     10,000,000  shares,  par value $1.00 per share,  are to be Series Preferred
     Stock; and

     140,000,000 shares, par value $.01 per share, are to be Common Stock.

     The relative voting,  dividend,  liquidation and other rights,  preferences
and limitations of the shares of each class are as follows:

         I. The  Preferred  Stock may be issued from time to time in one or more
     series, each such series to have the number of shares and designation,  and
     the shares of each such series to have such relative rights, preferences or
     limitations,  as  the  Board  of  Directors,  subject  to  the  limitations
     prescribed  by law or provided  herein,  may from time to time fix,  before
     issuance,   by  filing  an   appropriate   certificate   ("Certificate   of
     Designation")   with  the  Secretary  of  State  pursuant  to  the  General
     Corporation  Law of the State of  Delaware.  The  authority of the Board of
     Directors with respect to each series shall include, but not be limited to,
     the fixing of the following:

              (a)  The  number  of  shares  to  constitute  the  series  and the
              distinctive designation thereof;

<PAGE>

              (b)  The  dividend  rate  on the  shares  of the  series;  whether
              dividends  shall be  cumulative,  and,  if so,  from  what date or
              dates;

              (c)  Whether or not the shares of the series  shall be  redeemable
              and, if redeemable,  the terms upon which the shares of the series
              may be redeemed  and the premium,  if any,  over and above the par
              value thereof and any dividends accrued thereon which the share of
              the  series  shall be  entitled  to  receive  upon the  redemption
              thereof;

              (d)  Whether or not the  shares of the series  shall be subject to
              the operation of a retirement or sinking fund to be applied to the
              purchase or redemption of such shares for retirement  and, if such
              retirement  or sinking  fund be  established,  the  annual  amount
              thereof and the terms and  provisions  relative  to the  operation
              thereof;

              (e) Whether or not the shares of the series  shall be  convertible
              into  shares of any class or classes of stock of the  Corporation,
              with or  without  par  value,  or of any other  series of the same
              class and, if convertible,  the conversion  price or prices or the
              rate at which such conversion may be made and the method,  if any,
              of adjusting the same;  (f) The rights of the shares of the series
              in the event of voluntary or involuntary liquidation,  dissolution
              or winding-up of the Corporation;

              (g) The  restrictions,  if any, on the payment of dividends  upon,
              and the making of the  distributions to any class of stock ranking
              junior to the shares of the series, and the restrictions,  if any,
              on the  purchase  or  redemption  of the shares of any such junior
              class;

              (h) Whether the series  shall have voting  rights,  in addition to
              the voting  rights  provided by law, and, if so, the terms of such
              voting rights; and

              (i) Any other relative rights,  preferences and limitations of the
              series.

         II. Holders of shares of Preferred  Stock shall be entitled to receive,
     when and as  declared  by the  Board  of  Directors,  out of funds  legally
     available for the payment of dividends, dividends at the rates fixed by the
     Board of Directors for the respective series, before any dividends shall be
     declared and paid, or set apart for payment, on any other class of stock of
     the  Corporation  ranking  junior  to  the  Preferred  Stock  either  as to
     dividends or assets, with respect to the same dividend period.

         III. Whenever, at any time, dividends on the then outstanding Preferred
     Stock as may be  required  by the  terms of the  certificate  creating  the
     series representing the shares outstanding shall have been paid or declared
     and set apart for payment on the then outstanding Preferred Stock and after
     complying with all the provisions with respect to

<PAGE>

     any retirement or sinking fund or funds for any series of Preferred  Stock,
     the Board of  Directors may,  subject to the provisions of any  certificate
     creating  any  series of  Preferred  Stock  with  respect to the payment of
     dividends on any other class or classes of stock, declare and pay dividends
     on the Common Stock, and the Preferred Stock shall not be entitled to share
     therein.

         IV. Upon any liquidation, dissolution or winding-up of the Corporation,
     after  payment  if any is  required,  shall  have  been made in full to the
     Preferred Stock as provided in any certificate creating any series thereof,
     but not prior  thereto,  the Common Stock shall,  subject to the respective
     terms and  provisions,  if any,  of any such  certificate,  be  entitled to
     receive any and all assets  remaining  to be paid or  distributed,  and the
     Preferred Stock shall not be entitled to share therein.

         V. No holder of Common Stock or any series of Preferred Stock shall, as
     such holder,  have  any(preemptive or preferential right of subscription to
     any stock of any class of the Corporation or to any obligations convertible
     into any such stock or to any right of  subscription  to, or to any warrant
     or option for, the purchase of any stock,  other than such,  if any, as the
     Board of Directors of the  Corporation in its discretion may determine from
     time to time.

         VI. The holders of the Common Stock shall have the right to vote on all
     questions to the exclusion of all other classes of stock,  except as by law
     expressly  provided or as otherwise  expressly provided with respect to the
     holders of any other class or classes of stock.

4A.  Series A Junior Participating Preferred Stock.

         (1) Designation and Amount.  An aggregate of 1,000,000 shares of Series
     Preferred Stock, par value $1.00, of the Corporation are hereby constituted
     as a series designated as "Series A Junior  Participating  Preferred Stock"
     (the "Series A Preferred Stock").

         (2) Dividends and Distributions.

              (a) Subject to the prior and superior rights of the holders of any
     shares of any series of Preferred  Stock or any similar stock ranking prior
     and superior to the Series A Preferred Stock with respect to dividends, the
     holders of shares of Series A Preferred Stock, in preference to the holders
     of Common Stock of the Corporation, and of any other junior stock, shall be
     entitled to receive, when, as and if declared by the Board of Directors out
     of funds legally available for the purpose,  quarterly dividends payable in
     cash on the first day of  January,  April,  July and  October  in each year
     (each such date being referred to herein as a "Quarterly  Dividend  Payment
     Date"),  commencing on the first Quarterly  Dividend Payment Date after the
     first  issuance  of a share or  fraction  of a share of Series A  Preferred
     Stock,  in an amount per share  (rounded to the nearest  cent) equal to the
     greater  of  (a)  $___  or (b)  subject  to the  provision  for  adjustment
     hereinafter set forth, 100 times the aggregate per share amount of all cash
     dividends, and 100 times

<PAGE>

     the aggregate per share amount (payable in kind) of all non-cash  dividends
     or other  distributions,  other than a dividend payable in shares of Common
     Stock or a  subdivision  of the  outstanding  shares of Common  Stock  (by,
     reclassification  or  otherwise),  declared  on the Common  Stock since the
     immediately  preceding  Quarterly Dividend Payment Date or, with respect to
     the first Quarterly  Dividend Payment Date, since the first issuance of any
     share or fraction of a share of Series A Preferred  Stock. In the event the
     Corporation  shall at any time  declare or pay any  dividend  on the Common
     Stock  payable  in shares  of Common  Stock,  or  effect a  subdivision  or
     combination or consolidation of the outstanding  shares of Common Stock (by
     reclassification  or  otherwise  than by payment of a dividend in shares of
     Common  Stock) into a greater or lesser  number of shares of Common  Stock,
     then in each such case the  amount to which  holders  of shares of Series A
     Preferred Stock were entitled  immediately prior to such event under clause
     (b) of the preceding  sentence shall be adjusted by multiplying such amount
     by a  fraction,  the  numerator  of which is the number of shares of Common
     Stock outstanding immediately after such event and the denominator of which
     is the number of shares of Common Stock that were  outstanding  immediately
     prior to such event.

              (b) The  Corporation  shall declare a dividend or  distribution on
     the Series A Preferred  Stock as provided in paragraph  (a) of this Section
     immediately  after it  declares a dividend  or  distribution  of the Common
     Stock (other than a dividend  payable in shares of Common Stock);  provided
     that, in the event no dividend or distribution  shall have been declared on
     the Common Stock during the period between any Quarterly  Dividend  Payment
     Date and the next subsequent Quarterly Dividend Payment Date, a dividend of
     $__ per share on the Series A Preferred Stock shall nevertheless be payable
     on such subsequent Quarterly Dividend Payment Date.

              (c)  Dividends   shall  begin  to  accrue  and  be  cumulative  on
     outstanding  shares of Series A Preferred Stock from the Quarterly Dividend
     Payment Date next  preceding  the date of issue of such shares,  unless the
     date of issue of such  shares  is prior to the  record  date for the  first
     Quarterly  Dividend  Payment Date,  in which case  dividends on such shares
     shall begin to accrue from the date of issue of such shares,  or unless the
     date of issue is a Quarterly  Dividend  Payment Date or is a date after the
     record  date  for the  determination  of  holders  of  shares  of  Series A
     Preferred  Stock  entitled to receive a quarterly  dividend and before such
     Quarterly  Dividend  Payment Date, in either of which events such dividends
     shall  begin to  accrue  and be  cumulative  from such  Quarterly  Dividend
     Payment  Date.  Accrued  but  unpaid  dividends  shall  not bear  interest.
     Dividends paid on the shares of Series A Preferred  Stock in an amount less
     than the total amount of such  dividends at the time accrued and payable on
     such shares shall be allocated pro rata on a share-by-share basis among all
     such  shares  at the time  outstanding.  The Board of  Directors  may fix a
     record date for the determination of holder of shares of Series A Preferred
     Stock entitled to receive  payment of a dividend or  distribution  declared
     thereon, which record date shall be not more than 60 days prior to the date
     fixed for the payment thereof.


<PAGE>

         (3) Voting  Rights.  The holders of shares of Series A Preferred  Stock
     shall have the following voting rights.

              (a) Subject to the provision for adjustment hereinafter set forth,
     each share of Series A Preferred  Stock shall entitle the holder thereof to
     100 votes on all matters  submitted  to a vote of the  shareholders  of the
     Corporation.  In the event the Corporation shall at any time declare or pay
     any  dividend on the Common  Stock  payable in shares of Common  Stock,  or
     effect a subdivision  or combination or  consolidation  of the  outstanding
     shares of Common Stock by  reclassification or otherwise than by payment of
     a dividend in shares of Common  Stock)  into a greater or lesser  number of
     shares of  Common  Stock,  then in each  such case the  number of votes per
     share to which holders of shares of Series A Preferred  Stock were entitled
     immediately  prior to such event  shall be  adjusted  by  multiplying  such
     number by a  fraction,  the  numerator  of which is the number of shares of
     Common Stock  outstanding  immediately after such event and the denominator
     of which is the  number  shares  of  Common  Stock  that  were  outstanding
     immediately prior to such event.

              (b) Except as otherwise  provided herein, in any other Certificate
     of  Designation  establishing  a series of  Preferred  Stock or any similar
     stock, or by law, the holders of shares of Series A Preferred Stock and the
     holders  of  shares of Common  Stock  and any  other  capital  stock of the
     Corporation  having  general voting rights shall vote together as one class
     on all matters submitted to a vote of shareholders of the Corporation.

              (c)  Except as  otherwise  set forth  herein,  holders of Series A
     Preferred Stock shall have no voting rights.

         (4) Certain Restrictions.

              (a)   Whenever   quarterly   dividends   or  other   dividends  or
     distributions  payable  on the  Series A  Preferred  Stock as  provided  in
     Section 2 are in  arrears,  thereafter  and until all  accrued  and  unpaid
     dividends and distributions,  whether or not declared on shares of Series A
     Preferred Stock  outstanding  shall have been paid in full, the Corporation
     shall not:

                   (i)   declare   or  pay   dividends,   or  make   any   other
              distributions, on any shares of stock ranking junior (either as to
              dividends or upon  liquidation,  dissolution or winding-up) to the
              Series A Preferred Stock;

                   (ii)   declare   or  pay   dividends,   or  make  any   other
              distributions,  on any shares of stock ranking on a parity (either
              as to dividends or upon  liquidation,  dissolution  or winding-up)
              with the Series A Preferred  Stock,  except dividends paid ratably
              on the Series A Preferred Stock and all such parity stock on which
              dividends  are  payable or in arrears in  proportion  to the total
              amounts to which the holders of all such shares are then entitled;


<PAGE>

                   (iii)   redeem  or   purchase   or   otherwise   acquire  for
              consideration  shares of any stock  ranking  junior  (either as to
              dividends or upon  liquidation,  dissolution or winding-up) to the
              Series A Preferred Stock, provided that the Corporation may at any
              time  redeem,  purchase or  otherwise  acquire  shares of any such
              junior   stock  in  exchange  for  shares  of  any  stock  of  the
              Corporation  ranking  junior  (either  as  to  dividends  or  upon
              dissolution,  liquidation or winding-up) to the Series A Preferred
              Stock; or

                   (iv)   redeem  or   purchase   or   otherwise   acquire   for
              consideration  any  shares of  Series A  Preferred  Stock,  or any
              shares of stock  ranking on a parity  with the Series A  Preferred
              Stock,  except in accordance with a purchase offer made in writing
              or by publication (as determined by the Board of Directors) to all
              holders of such shares upon such terms as the Board of  Directors,
              after  consideration  of the respective  annual dividend rates and
              other relative rights and preferences of the respective series and
              classes.  shall  determine  in good faith will  result in fair and
              equitable treatment among the respective series or classes.

              (b)  The  Corporation  shall  not  permit  any  subsidiary  of the
     Corporation to purchase or otherwise  acquire for  consideration any shares
     of stock of the Corporation  unless the Corporation  could, under paragraph
     (a) of this Section 4,  purchase or  otherwise  acquire such shares at such
     time and in such manner.

         (5) Reacquired Shares. Any shares of Series A Preferred Stock purchased
     or otherwise  acquired by the Corporation in any manner whatsoever shall be
     retired and  canceled  promptly  after the  acquisition  thereof.  All such
     shares shall upon their cancellation  become authorized but unissued shares
     of Preferred Stock and may be reissued as part of a new series of Preferred
     Stock  subject to the  conditions  and  restrictions  on issuance set forth
     herein,  in  this  Restated  Certificate  of  Incorporation,  in any  other
     Certificate of Amendment  establishing  a series of Preferred  Stock or any
     similar stock or as otherwise required by law.

         (6)  Liquidation,  Dissolution,  or Winding-Up.  Upon any  liquidation,
     dissolution or winding-up of the Corporation, no distribution shall be made
     (i) to the holder of shares of stock ranking junior (either as to dividends
     or upon  liquidation,  dissolution or winding-up) to the Series A Preferred
     Stock unless,  prior  thereto,  the holders of shares of Series A Preferred
     Stock shall have received  $100 per share,  plus an amount equal to accrued
     and unpaid dividends and distributions thereon, whether or not declared, to
     the date of such  payment,  provided that the holders of shares of Series A
     Preferred Stock shall be entitled to receive an aggregate amount per share,
     subject to the provision for adjustment hereinafter set forth, equal to 100
     times the aggregate amount to be distributed per share to holders of shares
     of Common  Stock,  or (ii) to the  holders of shares of stock  ranking on a
     parity  (either  as  to  dividends  or  upon  liquidation,  dissolution  or
     winding-up) with the Series A Preferred Stock,  except  distributions  made
     ratably  on the  Series A,  Preferred  Stock and all such  parity  stock in
     proportion to the total amounts to which the holders of all such shares are
     entitled upon such  liquidation,  dissolution or wind-up.  In the event the

<PAGE>

     Corporation  shall at any time  declare or pay any  dividend  on the Common
     Stock  payable  in shares  of Common  Stock,  or  effect a  subdivision  or
     combination or consolidation of the outstanding  shares of Common Stock (by
     reclassification  or  otherwise  than by payment of a dividend in shares of
     Common  Stock) into a greater or lesser  number of shares of Common  Stock,
     then in each such case the  aggregate  amount to which holders of shares of
     Series A  Preferred  Stock were  entitled  immediately  prior to such event
     under  the  provision  in clause  (i) of the  preceding  sentence  shall be
     adjusted by multiplying  such amount by a fraction,  the numerator of which
     is the number of shares of Common Stock outstanding  immediately after such
     event and the  denominator of which is the number of shares of Common Stock
     that were outstanding immediately prior to such event.

         (7)  Consolidation,  Merger,  etc. In case the Corporation  shall enter
     into any consolidation,  merger,  combination or other transaction in which
     the shares of Common Stock are exchanged for or changed into other stock or
     securities,  cash  and/or  any other  property,  then in any such case each
     share of  Series A  Preferred  Stock  shall at the same  time be  similarly
     exchanged or changed into an amount per share, subject to the provision for
     adjustment  hereinafter set forth,  equal to 100 times the aggregate amount
     of stock,  securities,  cash and/or any other property, as the case may be,
     into which or for which each share of Common Stock is changed or exchanged.
     In the event the Corporation  shall at any time declare or pay any dividend
     on the  Common  Stock  payable  in  shares  of  Common  Stock,  or effect a
     subdivision or combination or  consolidation  of the outstanding  shares of
     Common  Stock  (by  reclassification  or  otherwise  than by  payment  of a
     dividend  in shares of Common  Stock)  into a greater  or lesser  number of
     shares of Common Stock,  then in each such case the amount set forth in the
     preceding  sentence  with  respect to the  exchange  or change of shares of
     Series A Preferred Stock shall be adjusted by multiplying  such amount by a
     fraction,  the  numerator  of which is the number of shares of Common Stock
     outstanding  immediately  after such event and the  denominator of which is
     the  number of shares of Common  Stock  that were  outstanding  immediately
     prior to such event.

         (8)  Redemption.  The shares of Series A  Preferred  Stock shall not be
     redeemable.

         (9) Rank.  The Series A Preferred  Stock shall rank junior with respect
     to the payment of dividends and the distribution of assets to all series of
     any class of Preferred Stock or any similar stock that specifically provide
     that they shall rank prior to the Series A Preferred Stock.  Nothing herein
     shall preclude the Board from creating any series of Preferred Stock or any
     similar  stock  ranking on a parity with or prior to the Series A Preferred
     Stock as to the payment of dividends or the distribution of assets.

         (10)  Amendment.  This Restated  Certificate  of  Incorporation  of the
     Corporation shall not be amended in any manner which would materially alter
     or change  the  powers,  preferences  or  special  rights  of the  Series A
     Preferred  Stock  so  as  to  affect  such  Series  adversely  without  the
     affirmative  vote of the holders of at least  two-thirds of the outstanding
     shares of Series A Preferred Stock, voting together as a single series.


<PAGE>

5.   Directors. (a) The business and affairs of the Corporation shall be managed
by a Board of Directors  consisting  of not less than three nor more than twelve
persons.   The  exact  number  of  directors  within  the  minimum  and  maximum
limitations specified in the preceding sentence shall be fixed from time to time
by the Board of Directors  pursuant to a resolution  adopted by the  affirmative
vote of a majority of the entire Board of Directors; and such exact number shall
be eight unless otherwise determined by a resolution so adopted by a majority of
the  entire  Board  of  Directors.  As  used  in this  Restated  Certificate  of
Incorporation,  the term "entire Board of Directors"  means the total authorized
number of directors which the Corporation would have if there were no vacancies.

     As of the Distribution Date (as defined in the Transaction  Agreement dated
as of _______,  1996 among Corning  Incorporated,  Corning Life  Sciences  Inc.,
Corning Clinical  Laboratories  Inc. and Corning  Pharmaceutical  Services Inc.)
(the "Distribution Date"), the directors shall be divided into three classes, as
nearly equal in number as  possible,  with the term of office of the first class
to expire at the 1998 Annual Meeting of Stockholders,  the term of office of the
second class to expire at the 1999 Annual Meeting of Stockholders,  and the term
of  office  of  the  third  class  to  expire  at the  2000  Annual  Meeting  of
Stockholders. Commencing with the 1997 Annual Meeting of Stockholders, directors
elected to succeed those directors  whose terms have thereupon  expired shall be
elected for a term of office to expire at the third succeeding Annual Meeting of
Stockholders  after their election.  If the number of directors is changed,  any
increase or decrease shall be apportioned among the classes so as to maintain or
attain, if possible,  the equality of the number of directors in each class, but
in no case will a decrease  in the number of  directors  shorten the term of any
incumbent director.  If such equality is not possible,  the increase or decrease
shall be apportioned  among the classes in such a way that the difference in the
number of directors in any two classes shall not exceed one.

     (b) Subject to the rights of the holders of any series of  Preferred  Stock
or any other class of capital  stock of the  Corporation  (other than the Common
Stock) then  outstanding,  vacancies in any class of directors  resulting from a
newly created directorship,  death, resignation,  retirement,  disqualification,
removal from office or other cause shall,  if occurring  prior to the expiration
of the term of office of such class, be filled only by the affirmative vote of a
majority of the  remaining  directors of the entire  board of Directors  then in
office,  although less than a quorum,  or by the sole  remaining  director.  Any
director so elected  shall hold office until the next  election of the class for
which such  directors  shall have been chosen and until his successor is elected
and qualified.  No decrease in the number of directors shall shorten the term of
any incumbent director.

     (c)  Whenever  the  holders of any one or more  series of  Preferred  Stock
issued by the Corporation shall have the right,  voting separately by series, to
elect directors at an annual or special meeting of  stockholders,  the election,
term of office,  filling of vacancies and other  features of such  directorships
shall be governed by this Paragraph 5 unless expressly otherwise provided by the
resolution or resolutions providing for the creation of such series.

     (d) Subject to the rights of the holders of any series of  Preferred  Stock
or any other class of capital  stock of the  Corporation  (other than the Common
Stock) then outstanding, (i) any

<PAGE>

director,  or the entire Board of Directors,  may be removed by the stockholders
from office at any time prior to the expiration of his term of office,  but only
for  cause,  and  only by the  affirmative  vote of the  holders  of  record  of
outstanding  shares  representing  a majority of the voting  power of all of the
outstanding  shares  of  capital  stock  of the  Corporation  entitled  to  vote
generally  in the  election of  directors,  and (ii) any director may be removed
from  office  by the  affirmative  vote of a  majority  of the  entire  Board of
Directors,  at any time prior to the expiration of his term of office,  but only
for cause.

     (e)  Notwithstanding  any other  provision of the Restated  Certificate  of
Incorporation and subject to the other provisions of this Paragraph 5, the Board
of Directors  shall  determine  the rules and  procedures  that shall affect the
Directors'  power  to  manage  and  direct  the  business  and  affairs  of  the
Corporation.  Without  limiting the foregoing,  the Board of Directors (1) shall
designate and empower committees of the Board of Directors,  (2) shall elect and
empower the  officers  of the  Corporation,  (3) may  appoint and empower  other
officers and agents of the  Corporation,  and (4) shall  determine  the time and
place of, and the notice requirements for, Board meetings, as well as quorum and
voting requirements for, and the manner of taking, Board actions.

6.   Business Combinations. Section 1. Certain Definitions.

     For the purposes of this Paragraph 6:

     A. "Business Combination" shall mean:

     (i) any merger or  consolidation  of the Corporation or any Subsidiary with
(a) an  Interested  Stockholder  or (b) any other  corporation  (whether  or not
itself  an   Interested   Stockholder)   which  is,  or  after  such  merger  or
consolidation would be, an Affiliate or Associate of an Interested  Stockholder;
or

     (ii)  any  sale,  lease,  exchange,  mortgage,  pledge,  transfer  or other
disposition  (in one  transaction  or a series  of  transactions)  to or with an
Interested Stockholder or an Affiliate or Associate of an Interested Stockholder
of any assets of the  Corporation  or any  Subsidiary  having an aggregate  Fair
Market Value of $20,000,000 or more; or

     (iii) the issuance or transfer by the Corporation or any Subsidiary (in one
transaction or a series of transactions) of any securities of the Corporation or
any  Subsidiary to an interested  Stockholder or an Affiliate or Associate of an
Interested  Stockholder in exchange for cash, securities or other property (or a
combination  thereof)  having an aggregate  Fair Market Value of  $20,000,000 or
more; or

     (iv)  the  adoption  of  any  plan  or  proposal  for  the  liquidation  or
dissolution  of  the  Corporation  proposed  by or on  behalf  of an  Interested
Stockholder or an Affiliate or Associate of an Interested Stockholder; or


<PAGE>

     (v) any reclassification of securities (including any reverse stock split),
or  recapitalization  of the Corporation,  or any merger or consolidation of the
corporation with any Subsidiary or any other transaction (whether or not with or
into or otherwise  involving an  Interested  Stockholder)  which has the effect,
directly, or indirectly,  of increasing the percentage of the outstanding shares
of (a) any class of equity  securities of the  Corporation  or any Subsidiary or
(b) any class of securities of the  Corporation  or any  Subsidiary  convertible
into equity  securities of the  Corporation  or any  Subsidiary,  represented by
securities of such class which are directly or indirectly owned by an Interested
Stockholder and all of its Affiliates and Associates; or

     (vi) any agreement,  contract or other arrangement providing for any one or
more of the actions specified in clauses (i) through (v) of this Section 1A.

     B. "Affiliate" or "Associate"  shall have the respective  meanings ascribed
to such  terms in Rule  12b-2 of the  General  Rules and  Regulations  under the
Securities  Exchange Act of 1934, as amended (the "Exchange  Act"), as in effect
on January 1, 1997.

     C. "Beneficial  Owner" shall have the meaning ascribed to such term in Rule
13d-3 of the General Rules and Regulations  under the Exchange Act, as in effect
on January 1, 1997.

     D.  "Continuing  Director"  shall  mean  (i) any  member  of the  Board  of
Directors  of the  Corporation  who (a) is neither  the  Interested  Stockholder
involved in the Business  Combination as to which a vote of Continuing Directors
is provided hereunder, nor an Affiliate,  Associate, employee, agent, or nominee
of such Interested Stockholder, or the relative of any of the foregoing, and (b)
was a member of the Board of Directors of the Corporation prior to the time that
such Interested Stockholder became an Interested Stockholder, (ii) any successor
of a Continuing  Director  described in clause (i) who is recommended or elected
to succeed a  Continuing  Director  by the  affirmative  vote of a  majority  of
Continuing  Directors  then on the Board of  Directors of the  Corporation,  and
(iii) any person who is a member of the Board of Directors of the Corporation at
the Distribution Date and any successor thereto who is recommended or elected by
the affirmative vote of a majority of the Continuing Directors then on the Board
of Directors of the Corporation.

          E.  "Fair  Market  Value"  shall  mean:  (i) in the case of stock, the
highest  closing sale price during the 30 day period  immediately  preceding the
date in  question  of a share of such stock on the  Composite  Tape for New York
Stock Exchange Listed Stocks, or, if such stock is not reported on the Composite
Tape on the New York  Stock  Exchange,  or, if such  stock is not listed on such
Exchange,  on the principal United States securities  exchange  registered under
the Exchange Act on which such stock is listed,  or, if such stock is not listed
on any such exchange,  the highest closing bid quotation with respect to a share
of such stock  during the 30-day  period  preceding  the date in question on the
National Association of Securities Dealers,  Inc. Automated Quotations System or
any similar  inter-dealer  quotation system then in use, or if no such quotation
is  available,  the fair market value on the date in question of a share of such
stock as determined by a majority of the Continuing Directors in good faith; and
(ii) in the case of property other than cash or stock,  the fair market value of
such  property  on the date in  question  as  determined  by a  majority  of the
Continuing Directors in good faith.


<PAGE>

     F.  "Interested   Stockholder"  shall  mean  any  Person  (other  than  the
Corporation or any Subsidiary) who or which:

     (i) is, or was at any time within the two-year period  immediately prior to
the date in question, the Beneficial Owner of 10% or more of the voting power of
the then outstanding Voting Stock of the Corporation; or

     (ii) is an assignee of, or has otherwise succeeded to, any shares of Voting
Stock of the  Corporation of which an Interested  Stockholder was the Beneficial
Owner at any time within the two-year  period  immediately  prior to the date in
question,  if such assignment or succession shall have occurred in the course of
a transaction, or series of transactions, not involving a public offering within
the meaning of the Securities Act of 1933, as amended.

     For  the  purpose  of  determining   whether  a  Person  is  an  Interested
Stockholder,  the  outstanding  Voting Stock of the  Corporation  shall  include
unissued  shares  of Voting  Stock of the  Corporation  of which the  Interested
Stockholder  is the  Beneficial  Owner but shall not include any other shares of
Voting Stock of the Corporation which may be issuable pursuant to any agreement,
arrangement  or  understanding,  or upon  the  exercise  of  conversion  rights,
warrants  or  options,  or  otherwise,  to any Person who is not the  Interested
Stockholder.

     G. A "Person" shall mean any individual,  partnership,  firm,  corporation,
association,  trust, unincorporated organization or other entity, as well as any
syndicate or group deemed to be a person under Section 14(d) (2) of the Exchange
Act.

     H.  "Subsidiary"  shall mean any corporation of which the Corporation owns,
directly  or  indirectly,  (i) a majority  of the  outstanding  shares of equity
securities of such  corporation,  or (ii) shares having a majority of the voting
power  represented  by all of the  outstanding  shares of  Voting  Stock of such
corporation.  For  the  purpose  of  determining  whether  a  corporation  is  a
Subsidiary, the outstanding Voting Stock and shares of equity securities thereof
shall include  unissued shares of which the Corporation is the Beneficial  Owner
but,  except for the  purposes of Section IF, shall not include any other shares
which may be issuable  pursuant to any agreement,  arrangement or understanding,
or upon the exercise of conversion rights, warrants or options, or otherwise, to
any Person who is not the Corporation.

     I. "Voting  Stock" shall mean  outstanding  shares of capital  stock of the
relevant corporation entitled to vote generally in the election of directors.

          Section 2. Higher Vote for Business Combinations.

     In addition to any  affirmative  vote  required by law or by this  Restated
Certificate  of  Incorporation,  and except as otherwise  expressly  provided in
Section 3 of this  Paragraph  6, any  Business  Combination  shall  require  the
affirmative vote of the holders of record of outstanding shares  representing at
least eighty percent (80%) of the voting power of the then outstanding shares of
the Voting Stock of the Corporation, voting together as a single class, it being

<PAGE>

understood  that,  for  purposes of this  Paragraph  6, each share of the Voting
Stock of the  Corporation  shall have the number of votes granted to it pursuant
to Paragraph 4 of this Restated  Certificate of Incorporation.  Such affirmative
vote shall be required notwithstanding the fact that no vote may be required, or
that a lesser  percentage may be specified,  by law or in any agreement with any
national securities exchange or otherwise.

         Section 3. When Higher Vote is Not Required.

     The  provisions of Section 2 of this Paragraph 6 shall not be applicable to
any particular Business Combination, and such Business Combination shall require
only such  affirmative  vote, if any, of the  stockholders as is required by law
and any other provision of this Restated  Certificate of  Incorporation,  if the
conditions specified in either of the following paragraphs A and B are met:

     A. Approval by Continuing  Directors.  The Business  Combination shall have
     been  approved  by the  affirmative  vote of a majority  of the  Continuing
     Directors,  even if the Continuing  Directors do not constitute a quorum of
     the entire Board of Directors.

     B. Form of  Consideration,  Price and  Procedure  Requirements.  All of the
     following conditions shall have been met:

              (i) With  respect to each  share of each class of Voting  Stock of
         the Corporation  (including Common Stock),  the holder thereof shall be
         entitled  to receive on or before the date of the  consummation  of the
         Business Combination (the "Consummation Date"),  consideration,  in the
         form  specified  in Section 3 (B) (ii) hereof,  with an aggregate  Fair
         Market Value as of the Consummation  Date at least equal to the highest
         of the following:

              (a)  the  highest  per  share  price   (including   any  brokerage
              commissions,  transfer taxes and soliciting dealers' fees) paid by
              the  Interested  Stockholder  to which  the  Business  Combination
              relates,  or by any  Affiliate  or  Associate  of such  Interested
              Stockholder, for any shares of such class of Voting Stock acquired
              by it (1)  within the  two-year  period  immediately  prior to the
              first  public   announcement  of  the  proposal  of  the  Business
              Combination (the "Announcement Date") or (2) in the transaction in
              which it became an Interested Stockholder, whichever is higher;

              (b) the Fair Market  Value per share of such class of Voting Stock
              of the Corporation on the Announcement Date; and

              (c) the highest  preferential  amount per share,  if any, to which
              the  holders  of  shares  of such  class  of  Voting  Stock of the
              Corporation  are  entitled  in  the  event  of  any  voluntary  or
              involuntary   liquidation,   dissolution   or  winding-up  of  the
              Corporation.


<PAGE>

              (ii) The  consideration  to be received by holders of a particular
         class of outstanding Voting Stock of the Corporation  (including Common
         Stock) as  described  in Section 3(B) (i) hereof shall be in cash or if
         the  consideration  previously  paid by or on behalf of the  Interested
         Stockholder in connection with its acquisition of beneficial  ownership
         of shares of such class of Voting  Stock  consisted in whole or in part
         of  consideration  other  than  cash,  then  in the  same  form as such
         consideration.  If such payment for shares of any class of Voting Stock
         of the Corporation  has been made with varying forms of  consideration,
         the form of  consideration  for such  class of  Voting  Stock  shall be
         either cash or the form used to acquire the beneficial ownership of the
         largest  number  of shares of such  class of  Voting  Stock  previously
         acquired by the Interested Stockholder.

              (iii) After such  Interested  Stockholder has become an Interested
         Stockholder  and  prior  to the  Consummation  Date  of  such  Business
         Combination:  (a)  except  as  approved  by the  affirmative  vote of a
         majority of the Continuing Directors,  there shall have been no failure
         to declare  and pay at the regular  date  therefor  any full  quarterly
         dividends  (whether or not  cumulative)  on the  outstanding  preferred
         stock of the  Corporation,  if any;  (b) there  shall  have been (1) no
         reduction in the annual rate of  dividends  paid on the Common Stock of
         the Corporation  (except as necessary to reflect any subdivision of the
         Common Stock) except as approved by the affirmative  vote of a majority
         of the Continuing Directors, and (2) an increase in such annual rate of
         dividends as necessary to reflect any  reclassification  (including any
         reverse stock split),  recapitalization,  reorganization or any similar
         transaction  which has the effect of reducing the number of outstanding
         shares of Common  Stock,  unless the failure so to increase such annual
         rate  is  approved  by  the  affirmative  vote  of a  majority  of  the
         Continuing  Directors;  and (c) such Interested  Stockholder  shall not
         have become the  Beneficial  Owner of any  additional  shares of Voting
         Stock  of the  Corporation  except  as  part of the  transaction  which
         results  in  such   Interested   Stockholder   becoming  an  Interested
         Stockholder.

              (iv) After such  Interested  Stockholder  has become an Interested
         Stockholder,  such Interested  Stockholder  shall not have received the
         benefit,   directly  or  indirectly   (except   proportionately   as  a
         stockholder of the Corporation),  of any loans,  advances,  guarantees,
         pledges or other  financial  assistance or any tax credits or other tax
         advantages provided by the Corporation.

              (v) A proxy  or  information  statement  describing  the  proposed
         Business  Combination  and  complying  with  the  requirements  of  the
         Exchange Act and the General Rules and  Regulations  thereunder (or any
         subsequent  provisions  replacing such Act, rules or regulations) shall
         be mailed to the stockholders of the Corporation at least 45 days prior
         to the consummation of such Business  Combination  (whether or not such
         proxy or  information  statement  is required to be mailed  pursuant to
         such Act or subsequent provisions thereof).


<PAGE>

         Section 4. Powers of Continuing Directors

              A majority of the  Continuing  Directors  shall have the power and
         duty to  determine,  on the basis of  information  known to them  after
         reasonable  inquiry,  all facts necessary to determine  compliance with
         this Paragraph 6, including,  without limitation,  (A) whether a person
         is an Interested Stockholder,  (B) the number of shares of Voting Stock
         of the  Corporation  beneficially  owned by any  person,  (C) whether a
         person is an  Affiliate  or  Associate  of  another,  (D)  whether  the
         requirements  of paragraph B of Section 3 have been met with respect to
         any  Business  Combination,  and (E) whether  the assets  which are the
         subject of any Business  Combination  have, or the  consideration to be
         received for the issuance or transfer of securities by the  Corporation
         or any  Subsidiary in any Business  Combination  has, an aggregate Fair
         Market Value of $20,000,000  or more; and the good faith  determination
         of a majority of the  Continuing  Directors  on such  matters  shall be
         conclusive and binding for all the purposes of this Paragraph 6.

         Section 5. No Effect on Fiduciary Obligations

              A.  Nothing  contained  in this  Paragraph 6 shall be construed to
         relieve  the  members  of  the  Board  of  Directors  or an  Interested
         Stockholder from any fiduciary obligation imposed by law.

              B.  The fact  that  any  Business  Combination  complies  with the
         provisions  of Section 3 of this  Paragraph 6 shall not be construed to
         impose any fiduciary duty, obligation or responsibility on the Board of
         Directors,  or any member thereof, to approve such Business Combination
         or  recommend  its  adoption  or approval  to the  stockholders  of the
         Corporation,  nor shall such  compliance  limit,  prohibit or otherwise
         restrict in any manner the Board of Directors,  or any member  thereof,
         with  respect to  evaluations  of or actions and  responses  taken with
         respect to such Business Combination.

7.   Special Stockholder Meetings.  Except as otherwise required by law, special
meetings of the stockholders may be called only by the Board of Directors.

8.   Action by Unanimous Written Consent.  From and after the Distribution Date,
any action which may be taken at any annual or special  meeting of  stockholders
may be taken  without a meeting  without  prior  notice and  without a vote,  if
consent  in  writing,  setting  forth the action so taken,  shall be signed,  in
person or by proxy,  by the holders of all  outstanding  stock  entitled to vote
thereon and no action by non-unanimous written consent shall be permitted.

9.   By-Laws.  The Board of  Directors  shall  have the right to make,  alter or
repeal the By-Laws of the Corporation,  subject to the right of the stockholders
of the Corporation to alter or repeal any By-law made by the Board of Directors.

10.  Elections.  The  election of directors  of the  Corporation  need not be by
written ballot, unless the By-Laws of the Corporation otherwise provide.


<PAGE>

11.  Indemnification. (a) No director of the Corporation shall have any personal
liability to the Corporation or its stockholders for monetary damages for breach
of  fiduciary  duty as a  director,  provided  that  this  provision  shall  not
eliminate  or limit  the  liability  of a  director  (i) for any  breach  of the
director's duty of loyalty to the Corporation or its stockholders, (ii) for acts
or omissions  not in good faith or which  involve  intentional  misconduct  or a
knowing violation of law, (iii) under Section 174 of the General Corporation Law
of the State of Delaware,  or (iv) for any  transaction  from which the director
derived an improper personal benefit.

     (b) Each  person who was or is made a party or is  threatened  to be made a
party to or is  involved  in any  action,  suit or  proceeding,  whether  civil,
criminal,  administrative  or  investigative  (hereinafter a  "proceeding"),  by
reason  of the  fact  that  he or she is or was a  director  or  officer  of the
Corporation or is or was serving at the request of the Corporation as a director
or officer of another corporation or of a partnership,  joint venture,  trust or
other  enterprise,  including  service with respect to employee  benefit  plans,
whether the basis of such  proceeding  is alleged  action  either in an official
capacity as a director or officer or in any other  capacity  while  serving as a
director or officer,  shall be indemnified  and held harmless by the Corporation
to the fullest extent authorized by the General  Corporation Law of the State of
Delaware,  as the same exists or may  hereafter be amended  (but, in the case of
any  such  amendment,  only  to the  extent  that  such  amendment  permits  the
Corporation to provide  broader  indemnification  rights than said law permitted
the  Corporation  to provide  prior to such  amendment),  against all  expenses,
liability and loss (including  attorneys' fees,  judgments,  fines, excise taxes
pursuant to the Employee  Retirement Income Security Act of 1974, as amended, or
penalties and amounts paid or to be paid in settlement)  reasonably  incurred or
suffered by such person in connection therewith and such  indemnification  shall
continue  as to a person who has ceased to be a  director  or officer  and shall
inure  to  the  benefit  of  his or her  heirs,  executors  and  administrators;
provided, however, that, the Corporation shall indemnify any such person seeking
indemnification  in connection with a proceeding (or part thereof)  initiated by
such person only if such  proceeding  (or part  thereof) was  authorized  by the
Board of Directors of the Corporation.  The right to be indemnified conferred in
this  Paragraph 11 shall be a contract  right and shall  include the right to be
paid by the Corporation  the expenses  incurred in defending any such proceeding
in advance of its final  disposition;  provided,  however,  that, the payment of
such  expenses  incurred by the  director or officer in his or her capacity as a
director or officer (and not in any other capacity in which service was or is to
be  rendered by such person  while a director  or  officer,  including,  without
limitation,  service  to an  employee  benefit  plan),  in  advance of the final
disposition of proceeding,  shall be made only upon delivery to the  Corporation
of an  undertaking,  by or on behalf of such  director or officer,  to repay all
amounts so advanced if it shall  ultimately be determined  that such director or
officer is not entitled to be indemnified under this Paragraph or otherwise. The
Corporation  may,  by  action  of  its  Directors,  provide  indemnification  to
employees  and agents of the  Corporation  with the same scope and effect as the
foregoing indemnification of directors and officers.

     (c) The  indemnification  provided by this  Paragraph 11 shall not limit or
exclude any rights,  indemnities or limitations of liability to which any person
may  be  entitled,  whether  as a 

<PAGE>

matter of law, under the By-Laws of the Corporation,  by agreement,  vote of the
stockholders or disinterested directors of the Corporation or otherwise.

     (d) If a claim under paragraph (b) of this Paragraph 11 is not paid in full
by the  Corporation  within  sixty  (60)  days  after a  written  claim has been
received by the Corporation,  the claimant may at any time thereafter bring suit
against  the  Corporation  to  recover  the unpaid  amount of the claim and,  if
successful in whole or in part,  the claimant  shall be entitled to be paid also
the expense of prosecuting  such claim. It shall be a defense to any such action
(other  than an action  brought  to  enforce a claim for  expenses  incurred  in
defending any proceeding in advance of its final  disposition where the required
undertaking,  if any is required, has been tendered to the Corporation) that the
claimant has not met the  standards of conduct which make it  permissible  under
the General  Corporation  Law of the State of Delaware  for the  Corporation  to
indemnify  the claimant for the amount  claimed,  but the burden of proving such
defense  shall be on the  Corporation.  Neither the  failure of the  Corporation
(including its Board,  independent  legal counsel,  or its stockholders) to have
made  a   determination   prior  to  the   commencement   of  such  action  that
indemnification of the claimant is proper in the circumstances because he or she
has met the applicable  standard or conduct set forth in the General Corporation
Law of the State of Delaware,  nor an actual  determination  by the  Corporation
(including its Board,  independent legal counsel,  or its stockholders) that the
claimant  has not met  such  applicable  standard  of  conduct,  shall  create a
presumption that the claimant has not met the applicable standard of conduct.

     (e) The  Corporation  may maintain  insurance,  at its expense,  to protect
itself  and any  director,  officer,  employee  or agent of the  corporation  or
another  corporation,  partnership,  joint  venture,  trust or other  enterprise
against any such  expense,  liability  or loss,  whether or not the  Corporation
would have the power to indemnify such person against such expense, liability or
loss under the General Corporation Law of the State of Delaware.

12.  Amendment  or  Repeal.  The  affirmative  vote of the  holders of record of
outstanding  shares  representing  at least eighty  percent  (80%) of the voting
power of all the outstanding  Voting Stock of the Corporation  shall be required
to amend,  alter or repeal,  or adopt any provision or  provisions  inconsistent
with,  any provision of Paragraphs 6, 7 and 8 and this  Paragraph 12;  provided,
however,  that this  Paragraph  12 shall not apply to, and such  eighty  percent
(80%) vote shall not be  required  for,  any  amendment,  alteration,  repeal or
adoption of any inconsistent provision or provisions,  declared advisable by the
Board of Directors by the affirmative  vote of two-thirds of the entire Board of
Directors and a majority of the Continuing Directors.

<PAGE>

                            CERTIFICATE OF AMENDMENT
                                       OF
                          CERTIFICATE OF INCORPORATION
                                       OF
                                  COVANCE INC.


     Covance Inc.  (the  "Corporation"),  a  corporation  organized and existing
under and by virtue of the General Corporation Law of the State of Delaware,

     DOES HEREBY CERTIFY:

     FIRST:  At a  meeting  of the  Board of  Directors,  resolutions  were duly
adopted  authorizing  the  amendment  and  restatement  of  the  Certificate  of
Incorporation  of the  Corporation  as set forth in Exhibit A hereto,  declaring
said amendment to be advisable and presenting such amendment to the stockholders
of the Corporation for consideration thereof.

     SECOND:  That said  amendment was approved by the sole  stockholder  of the
Corporation by unanimous  written consent of such sole stockholder in accordance
with the General Corporation Law of the State of Delaware.

     THIRD:  That  said  amendment  was  duly  adopted  in  accordance  with the
provisions  of  Section  242 of the  General  Corporation  Law of the  State  of
Delaware.



IN WITNESS WHEREOF,  the Corporation has caused this certificate to be signed by
Jeffrey S. Hurwitz, its Senior Vice President, General Counsel and Secretary and
Diana I. Faillace,  its Vice President,  Associate General Counsel and Assistant
Secretary, this ____ day of November, 1996.


                                      By: ______________________________________
                                          Jeffrey S. Hurwitz
                                          Senior Vice President, General Counsel
                                          and Secretary
                           
                                  Attest: ______________________________________
                                          Diana I. Faillace
                                          Vice President, Associate General
                                          Counsel and Assistant Secretary

                                  COVANCE INC.

             A Delaware  corporation  (formerly known as Corning  Pharmaceutical
Services Inc.)


                          AMENDED AND RESTATED BY-LAWS


                           Effective November 6, 1996



<PAGE>

                                  COVANCE INC.

                             A Delaware corporation

                          AMENDED AND RESTATED BY-LAWS

                                TABLE OF CONTENTS

                                    ARTICLE I
                                  STOCKHOLDERS

                                                                    Page

Section         1.01       Annual Meetings..................................1
Section         1.02       Special Meetings.................................1
Section         1.03       Notice of Meetings...............................1
Section         1.04       Business Transacted at Special
                           Meetings of Stockholders.........................1
Section         1.05       Quorum...........................................1
Section         1.06       Nominations and Stockholder
                           Business.........................................2

                                   ARTICLE II
                               BOARD OF DIRECTORS

Section         2.01       General Powers...................................4
Section         2.02       Number and Term of Office........................4
Section         2.03       Annual and Regular Meetings......................4
Section         2.04       Special Meetings; Notice.........................4
Section         2.05       Telephonic Meetings..............................5
Section         2.06       Quorum and Vote..................................5
Section         2.07       Action Without a Meeting.........................5
Section         2.08       Manner of Acting.................................5
Section         2.09       Resignations.....................................5
Section         2.10       Reliance on Accounts and
                           Reports, etc.....................................5
Section         2.11       Committees.......................................5

                                   ARTICLE III
                                    OFFICERS

Section         3.01       Number and Designation...........................6
Section         3.02       Additional Officers..............................6


<PAGE>

                                                                    Page

Section         3.03       Election.........................................6
Section         3.04       Removal and Vacancies............................6
Section         3.05       Duties of the Chairman of
                           the Board of Directors...........................6
Section         3.06       Duties of the President..........................6
Section         3.07       Duties of the Vice President ....................7
Section         3.08       Duties of the Secretary..........................7
Section         3.09       Duties of the Treasurer..........................7
Section         3.10       Duties of the Controller.........................7
Section         3.11       Duties of the Assistant Secretary................7
Section         3.12       Duties of the Assistant Controller...............8
Section         3.13       Duties of the Assistant Treasurer................8

                                   ARTICLE IV
                  EXECUTION OF INSTRUMENTS; DEPOSITS; FINANCES

Section         4.01       General..........................................8
Section         4.02       Corporate Indebtedness...........................8
Section         4.03       Checks, Drafts, etc..............................8
Section         4.04       Deposits.........................................9
Section         4.05       Dividends........................................9
Section         4.06       Fiscal Year......................................9

                                    ARTICLE V
                                  CAPITAL STOCK

Section         5.01       Certificates of Stock............................9

                                   ARTICLE VI
                                  SEAL; OFFICES

Section         6.01       Seal.............................................9
Section         6.02       Offices.........................................10

                                   ARTICLE VII
                                 INDEMNIFICATION

Section         7.01       Indemnification.................................10

                                  ARTICLE VIII
                                   AMENDMENTS


Section         8.01       Amendments.......................................12


<PAGE>


                          AMENDED AND RESTATED BY-LAWS

                                       OF

                                  COVANCE INC.


                                    ARTICLE I

                                  STOCKHOLDERS

Section 1.01.  Annual  Meetings.  The annual meeting of the  stockholders of the
Corporation  for the election of directors and for the transaction of such other
business as properly  may come before such  meeting  shall be held at such place
either  within or outside the State of Delaware,  at such time and date as shall
be fixed from time to time by  resolution  of the Board of Directors  and as set
forth in the notice of the meeting.

Section 1.02.  Special  Meetings.  Special  meetings of the  stockholders may be
called at any time by the Chairman of the Board of Directors,  if any, or by the
President (or, in the absence or disability of the Chairman of the Board and the
President,  by any Vice President),  or by the Board of Directors.  Such special
meetings of the stockholders shall be held at such places, within or outside the
State of Delaware, as shall be specified in the respective notices or waivers of
notice thereof.

Section 1.03. Notice of Meetings. The Secretary or any Assistant Secretary shall
cause  written  notice  of the  date,  time  and  place of each  meeting  of the
stockholders to be given, at least ten but not more than fifty days prior to the
meeting,  to each  stockholder of record  entitled to vote. Such notice shall be
given  either  personally  or by mail or other  means of written  communication,
addressed to each  stockholder at the address of such  stockholder  appearing on
the books of the Corporation at the time such notice is dispatched. Such further
notice  shall be given as may be  required  by law.  Notice  of any  meeting  of
stockholders  need not be given to any  stockholder  who shall  sign a waiver of
such notice in writing, whether before or after the time of such meeting. Notice
of any adjourned  meeting of the  stockholders  of the  Corporation  need not be
given.

Section 1.04. Business Transacted at Special Meetings of Stockholders.  Business
transacted  at any  special  meeting  of  stockholders  shall be  limited to the
purposes stated in the notice thereof.

Section 1.05 Quorum.  Except as at the time otherwise  required by statute or by
the Restated  Certificate  of  Incorporation,  the presence at any  stockholders
meeting,  in person or by proxy, of the holders of record of shares of stock (of
any class) entitled to vote at the meeting,  aggregating a majority of the total
number  of  shares of stock of all  classes  then  issued  and  outstanding  and
entitled to vote at the meeting, shall be necessary and sufficient to constitute
a quorum for the transaction of business.

                                                                               1
<PAGE>

Section 1.06. Nominations and Stockholder Business.

(a) Annual Meeting of Stockholders.

(1)  Nominations  of  persons  for  election  to the Board of  Directors  of the
Corporation  and the proposal of business to be considered  by the  stockholders
may  be  made  at  an  annual  meeting  of  stockholders  (i)  pursuant  to  the
Corporation's  notice of meeting,  (ii) by or at the  direction  of the Board of
Directors or (iii) by any  stockholder of the  Corporation who was a stockholder
of record at the time of giving of notice provided for in this Section 1.06, who
is entitled to vote at the meeting and who complied  with the notice  procedures
set forth in this Section 1.06.

(2) For  nominations or other  business to be properly  brought before an annual
meeting by a  stockholder  pursuant to clause (iii) of paragraph  (a)(1) of this
Section 1.06, the  stockholder  must have given timely notice thereof in writing
to the Secretary of the Corporation.  To be timely, a stockholder's notice shall
be  delivered  to  the  Secretary  at the  principal  executive  offices  of the
Corporation  not  less  than 60 days nor more  than 90 days  prior to the  first
anniversary of the preceding year's annual meeting;  provided,  however, that in
the event that the date of the annual  meeting is  advanced by more than 30 days
or  delayed  by more  than 60 days  from such  anniversary  date,  notice by the
stockholder  to be timely must be so  delivered  not  earlier  than the 90th day
prior to such  annual  meeting  and not later than the close of  business on the
later of the 60th day prior to such annual meeting or the 10th day following the
day on which public announcement of the date of such meeting is first made. Such
stockholder's  notice shall set forth (i) as to each person whom the stockholder
proposes to nominate for election or  reelection  as a director all  information
relating to such person that is required to be  disclosed  in  solicitations  of
proxies for  election  of  directors,  or is  otherwise  required,  in each case
pursuant to Regulation 14A under the Securities Exchange Act of 1934, as amended
(the "Exchange Act")  (including such person's written consent to being named in
the proxy statement as a nominee and to serving as a director if elected);  (ii)
as to any other  business  that the  stockholder  proposes  to bring  before the
meeting,  a brief  description of the business  desired to be brought before the
meeting,  the  reasons  for  conducting  such  business  at the  meeting and any
material interest in such business of such stockholder and the beneficial owner,
if any, on whose  behalf the proposal is made;  and (iii) as to the  stockholder
giving  the  notice  and the  beneficial  owner,  if any,  on whose  behalf  the
nomination or proposal is made (A) the name and address of such stockholder,  as
they appear on the Corporation's books, and of such beneficial owner and (B) the
class and number of shares of the Corporation  which are owned  beneficially and
of record by such stockholder and such beneficial owner.

(3) Notwithstanding  anything in the second sentence of paragraph (a)(2) of this
Section  1.06 to the  contrary,  in the event that the number of directors to be
elected to the Board of Directors of the  Corporation  is increased and there is
no public announcement naming all of the nominees for Director or specifying the
size of the increased  Board of Directors

                                                                               2
<PAGE>

made by the  Corporation at least 70 days prior to the first  anniversary of the
preceding year's annual meeting, a stockholder's notice required by this Section
1.06 shall also be considered  timely, but only with respect to nominees for any
new position created by such increase, if it shall be delivered to the Secretary
at the principal  executive  offices of the Corporation not later than the close
of business on the 10th day following the day on which such public  announcement
is first made by the Corporation.

(b) Special Meetings of Stockholders. Only such business shall be conducted at a
special  meeting of  stockholders  as shall have been brought before the meeting
pursuant  to the  Corporation's  notice of meeting.  Nominations  of persons for
election  to the  Board  of  Directors  may be  made  at a  special  meeting  of
stockholders at which directors are to be elected pursuant to the  Corporation's
notice of meeting (i) by or at the  direction  of the Board of Directors or (ii)
by any stockholder of the Corporation who is a stockholder of record at the time
of giving of notice  provided for in this Section 1.06, who shall be entitled to
vote at the meeting and who  complies  with the notice  procedures  set forth in
this Section 1.06.  Nominations by  stockholders  of persons for election to the
Board of Directors may be made at such a special  meeting of stockholders if the
stockholder's  notice required by paragraph (a)(2) of this Section 1.06 shall be
delivered to the Secretary at the principal executive offices of the Corporation
not earlier than the 90th day prior to such special meeting,  and not later than
the close of business on the later of the 60th day prior to such special meeting
or the 10th day following the day on which public  announcement is first made of
the date of the  special  meeting and of the  nominees  proposed by the Board of
Directors to be elected at such meeting.

(c) General.

(1) Only such persons who are nominated in accordance  with the  procedures  set
forth in this Section 1.06 shall be eligible to serve as directors and only such
business  shall be  conducted  at a meeting of  stockholders  as shall have been
brought  before the meeting in accordance  with the procedures set forth in this
Section  1.06.  The  Chairman  of the  meeting  shall have the power and duty to
determine whether a nomination or any business proposed to be brought before the
meeting,  was made in accordance  with the  procedures set forth in this Section
1.06 and, if any proposed  nomination or business is not in compliance with this
Section 1.06, to declare that such defective proposal shall be disregarded.

(2)  For  purposes  of this  Section  1.06,  "public  announcement"  shall  mean
disclosure in a press release reported by the Dow Jones News Service, Associated
Press or comparable national news service or in a document publicly filed by the
Corporation with the Securities and Exchange Commission pursuant to Sections 13,
14 or 15(d) of the Exchange Act.

(3) Notwithstanding the foregoing provisions of this Section 1.06, a stockholder
shall also comply with all applicable  requirements  of the Exchange Act and the
rules and  regulations  thereunder with respect to the matters set forth in this
Section 1.06.  Nothing

                                                                               3
<PAGE>

in this  Section  1.06 shall be deemed to affect any rights of  stockholders  to
request inclusion of proposals in the Corporation's  proxy statement pursuant to
Rule 14a-8 under the Exchange Act.



                                   ARTICLE II

                               BOARD OF DIRECTORS

Section  2.01  General  Powers.  The  property,  affairs  and  business  of  the
Corporation  shall be managed by the Board of Directors.  The Board of Directors
may exercise all the powers of the Corporation,  whether derived from law or the
Restated Certificate of Incorporation, except such powers as are, by statute, by
the Restated Certificate of Incorporation or by these By-Laws,  vested solely in
the  stockholders of the  Corporation.  No Director need be a stockholder of the
Corporation.

Section 2.02 Number and Term of Office.  The Board of Directors shall consist of
such number (but in no event less than three nor more than  twelve) of Directors
as may be determined from time to time by resolution adopted by affirmative vote
of a majority of the whole Board of Directors.  Each Director (whenever elected)
shall hold office until his or her  successor  shall have been elected and shall
have  qualified,  or until  his or her  death,  or until  he or she  shall  have
resigned  in the  manner  provided  in  Section  2.09  hereof or shall have been
removed in accordance with the Restated Certificate of Incorporation.

Section  2.03 Annual and Regular  Meetings.  The annual  meeting of the Board of
Directors,  for the choosing of officers and for the  transaction  of such other
business as may come before the  meeting,  shall be held in each year as soon as
possible  after the  annual  meeting  of the  stockholders  at the place of such
annual  meeting of the  stockholders,  and notice of such annual  meeting of the
Board of  Directors  shall not be required to be given.  The Board of  Directors
from time to time may provide by resolution for the holding of regular  meetings
and fix the  time and  place  (which  may be  within  or  outside  the  State of
Delaware) thereof.  Notice of such regular meetings need not be given; provided,
however,  that in case the Board of  Directors  shall fix or change  the time or
place of regular meetings, notice of such action shall be given personally or by
mail, facsimile or similar means of communication  promptly to each Director who
shall not have been present at the meeting at which such action was taken.

Section  2.04  Special  Meetings;  Notice.  Special  meetings  of the  Board  of
Directors shall be held whenever called by the Chairman of the Board, if any, or
by the President  (or, in the absence or disability of the Chairman of the Board
and the President, by any Vice President), or by any two Directors, at such time
and place  (which may be within or outside of the State of  Delaware)  as may be
specified  in the  respective  notices  or waivers  of notice  thereof.  Special
meetings  of the Board of  Directors  may be called on two days'  notice to each
Director,  personally  or by  telephone  or facsimile or on four days' notice by
mail.  Notice of any special meeting need not be given to any Director who shall
be

                                                                               4
<PAGE>

present at such  meeting,  or to any  Director  who shall  waive  notice of such
meeting in writing,  whether  before or after the time of such meeting,  and any
business may be  transacted  thereat.  No notice need be given of any  adjourned
meeting.

Section 2.05 Telephonic Meetings.  Directors may participate in a meeting of the
Board of Directors,  or a meeting of any committee  designated by the Board,  by
means of conference  telephone or similar  communications  equipment by means of
which  all  persons  participating  in the  meeting  can hear  each  other,  and
participation in a meeting pursuant to this By-Law shall constitute  presence in
person at such meeting.

Section  2.06 Quorum and Vote.  At all meetings of the Board of  Directors,  the
presence of a majority of the total authorized number of Directors under Section
2.02 hereof shall be necessary  and  sufficient  to  constitute a quorum for the
transaction of business.  Except when otherwise required by statute, the vote of
a majority of the total number of  Directors  present and acting at a meeting at
which a quorum is  present  shall be the act of the Board of  Directors.  In the
absence of a quorum, a majority of the Directors present may adjourn the meeting
from time to time, until a quorum shall be present.

Section 2.07 Action  Without a Meeting.  Any action  required or permitted to be
taken at any meeting of the Board of  Directors or any meeting of a Committee of
the Board of  Directors  may be taken  without a meeting,  if  written  consents
thereto are signed by all  members of the Board or  Committee  and such  written
consents are filed with the minutes of proceedings of the Board.

Section 2.08 Manner of Acting.  The Directors shall act only as a Board, and the
individual  Directors  shall  have no power  as such,  except  as  permitted  by
statute.

Section 2.09  Resignations.  Any Director may resign at any time by delivering a
written resignation to the Chairman of the Board, if any, the President,  a Vice
President, the Secretary or any Assistant Secretary.  Unless otherwise specified
therein, such resignation shall take effect upon delivery.

Section 2.10 Reliance on Accounts and Reports,  etc. A Director,  or a member of
any committee designated by the Board of Directors, in the performance of his or
her duties,  shall be fully protected in relying in good faith on the records of
the  Corporation  and upon such  information,  opinions,  reports or  statements
presented to the Corporation by any of its officers or employees,  or committees
of the Board of  Directors  or by any other person as to matters the Director or
member reasonably believes are within such other person's professional or expert
competence and who has been selected with reasonable care by or on behalf of the
Corporation.

Section 2.11  Committees.  The Board may establish such  committees  having such
responsibilities  and  composition  as it shall from time to time by  resolution
determine.


                                                                               5
<PAGE>

                                   ARTICLE III

                                    OFFICERS

Section 3.01 Number and  Designation.  The officers of the Corporation  shall be
chosen by the Board of  Directors  and may  include a Chairman  of the Board,  a
President, a Vice President, a Secretary, a Controller and a Treasurer who shall
hold office  until  their  successors  are chosen and  qualify or their  earlier
resignation  or  removal.  The Board of  Directors  may also  choose  additional
Corporate  Vice  Presidents  and  Vice  Presidents,  and one or  more  Assistant
Secretaries,  Assistant Controllers and Assistant Treasurers. Any one or more of
such  Corporate  Vice  Presidents  and  Vice  Presidents  may be  designated  as
Corporate Executive Vice President,  Executive Vice President,  Corporate Senior
Vice  President or Senior Vice  President.  Any number of offices may be held by
the same person,  except that no person shall simultaneously hold the offices of
Chairman or President and Secretary, Treasurer or Controller. The Chairman shall
be a member of the Board of  Directors.  The Board may also  designate  any Vice
Presidents as Chief Financial Officer and as General Counsel.

Section 3.02 Additional Officers.  The Board of Directors may appoint such other
officers and agents as it shall deem  necessary who shall hold their offices for
such terms and shall  exercise  such powers and perform  such duties as shall be
determined  from time to time by the Board of Directors.  The Board of Directors
may also  delegate  its  Chairman  or the  President  to appoint and remove such
additional officers as the Chairman or the President,  as the case may be, shall
designate  in  writing,  with such  limited  authority  as shall be set forth in
writing, and such appointments shall be reported to the Board of Directors.

Section  3.03  Election.  The Board of  Directors  at its first  meeting or such
subsequent  meetings  as shall be held prior to its first  annual  meeting,  and
thereafter  annually at its annual  meeting,  shall  choose the  officers of the
Corporation.  If any officers are not chosen at an annual meeting, such officers
may be chosen at any subsequent regular or special meeting.

Section  3.04  Removal and  Vacancies.  Any officer  elected or appointed by the
Board of  Directors  may be  removed  at any time by the  affirmative  vote of a
majority of the Board of Directors,  either with or without  cause.  Any vacancy
occurring  in any  office  of the  Corporation  shall be  filled by the Board of
Directors.

Section 3.05 Duties of the Chairman of the Board of  Directors.  The Chairman of
the Board of Directors,  if present, shall preside at all stockholders' meetings
and all  meetings  of the Board at which he is present and shall have such other
duties  as shall  be  assigned  to him or her by the  Board  of  Directors.  The
Chairman may be the Chief Executive Officer of the Corporation.

                                                                               6
<PAGE>

Section 3.06 Duties of the President.  The President shall have direct charge of
the business of the Corporation,  subject to the general control of the Board of
Directors,  and may be the Chief  Executive  Officer and/or the Chief  Operating
Officer of the Corporation. In the absence of the Chairman of the Board or if no
Chairman of the Board has been chosen,  the President shall also have the duties
of the Chairman of the Board.

Section  3.07  Duties  of the Vice  President.  In the event of the  absence  or
disability  of the  Chairman  of the  Board  and the  President,  the  Corporate
Executive  Vice  President,  Executive  Vice  President,  Corporate  Senior Vice
President or Senior Vice  President,  if any, or if absent,  any Vice  President
designated  by the  Board of  Directors,  shall  perform  all the  duties of the
President,  and when so acting,  shall have all the powers of, and be subject to
all the restrictions  upon, the President.  Except where by law the signature of
the President is required,  each of the Vice  Presidents  shall possess the same
power as the  President to sign all  certificates,  contracts,  obligations  and
other  instruments of the  Corporation.  Any Vice  President  shall perform such
other  duties and may  exercise  such  other  powers as from time to time may be
assigned  to him or her by these  By-Laws  or by the Board of  Directors  or the
President. An Executive Vice President may be the Chief Operating Officer of the
Corporation.

Section 3.08 Duties of the Secretary.  The Secretary  shall, if present,  act as
Secretary  of, and keep the minutes of, all the  proceedings  of the meetings of
the stockholders and of the Board of Directors and of any committee of the Board
of Directors  in one or more books to be kept for that  purpose;  shall  perform
such other  duties as shall be  assigned to him or her by the  President  or the
Board of Directors;  and, in general,  shall perform all duties  incident to the
office of Secretary.

Section 3.09 Duties of the  Treasurer.  The Treasurer  shall keep or cause to be
kept full and accurate records of all receipts and disbursements in the books of
the  Corporation and shall have the care and custody of all funds and securities
of the Corporation. He or she shall disburse the funds of the Corporation as may
be ordered by the Board of  Directors,  shall  render to the  President  and the
Board of  Directors,  whenever  they request it, an account of all of his or her
transactions as Treasurer and shall perform such other duties as may be assigned
to him or her by the President or the Board of Directors; and, in general, shall
perform all duties incident to the office of Treasurer.

Section  3.10  Duties  of the  Controller.  The  Controller  shall be the  chief
accounting officer of the Corporation.  The Controller shall keep or cause to be
kept all books of account and accounting  records of the  Corporation  and shall
keep and  maintain,  or cause to be kept and  maintained,  adequate  and correct
accounts of the properties and business  transactions  of the  Corporation.  The
Controller  shall  prepare  or  cause  to  be  prepared  appropriate   financial
statements  for the  Corporation  and shall  perform such other duties as may be
assigned  to him or her by the  President  or the Board of  Directors;  and,  in
general, shall perform all duties incident to the office of Controller.


                                                                               7
<PAGE>

Section 3.11 Duties of the Assistant Secretary. The Assistant Secretary, if any,
shall,  in the absence or disability of the  Secretary,  exercise the powers and
perform the duties of the  Secretary,  and shall  perform  such other  duties as
shall be assigned to him or her by the President or the Board of Directors.

Section 3.12 Duties of the Assistant Controller.  The Assistant  Controller,  if
any, shall, in the absence or disability of the Controller,  exercise the powers
and perform the duties of the Controller, and shall perform such other duties as
shall be assigned to him or her by the President or the Board of Directors.

Section 3.13 Duties of the Assistant Treasurer. The Assistant Treasurer, if any,
shall,  in the absence or disability of the  Treasurer,  exercise the powers and
perform the duties of the  Treasurer,  and shall  perform  such other  duties as
shall be assigned to him or her by the President or the Board of Directors.


                                   ARTICLE IV

                  EXECUTION OF INSTRUMENTS; DEPOSITS; FINANCES

Section 4.01 General.  Subject to the provisions of Sections 4.02, 4.03 and 4.04
hereof, all deeds,  documents,  transfers,  contracts,  and agreements and other
instruments  requiring  execution  by the  Corporation  shall be  signed  by the
Chairman of the Board, the President,  a Vice President or the Treasurer,  or as
the Board of Directors may otherwise  from time to time authorize by resolution.
Any such authorization may be general or confined to specific instances.

Section 4.02  Corporate  Indebtedness.  No loan shall be contracted on behalf of
the Corporation,  and no evidences of indebtedness  shall be issued in its name,
unless  authorized by the Board of Directors.  Such  authorizations of the Board
may be general or confined to specific instances.  Loans authorized by the Board
of  Directors  may be  effected at any time for the  Corporation  from any bank,
trust company or other institution, or from any firm, corporation or individual.
All bonds, debentures,  notes and other obligations or evidences of indebtedness
of the  Corporation  issued for such loans as the Board shall authorize shall be
made,  executed and  delivered as the Board of Directors  shall  authorize.  All
notes and other  obligations or evidences of  indebtedness  permitted  hereunder
without  authorization  of  the  Board  of  Directors  shall  be  signed  by the
President, a Vice President or the Treasurer. When so authorized by the Board of
Directors, any part of or all the properties, including contract rights, assets,
business  or  goodwill  of the  Corporation,  whether  then owned or  thereafter
acquired,  may be mortgaged,  pledged,  hypothecated  or conveyed or assigned in
trust as security  for the payment of such  bonds,  debentures,  notes and other
obligations or evidences of indebtedness to the Corporation, and of the interest
thereon, by instruments executed and delivered in the name of the Corporation.


                                                                               8
<PAGE>

Section  4.03 Checks,  Drafts,  etc.  All checks,  drafts,  bills of exchange or
orders for the payment of money, issued in the name of the Corporation, shall be
signed only by the  Treasurer or such other person or persons and in such manner
as may  from  time  to time be  designated  by the  Board  of  Directors,  which
designation  may be general or  confined to  specific  instances;  and unless so
designated,  no person  shall  have any power or  authority  thereby to bind the
Corporation or to pledge its credit or to render it liable.

Section 4.04 Deposits. All funds of the Corporation not otherwise employed shall
be deposited  from time to time to the credit of the  Corporation in such banks,
trust companies or other  depositories as the Board of Directors may select. The
Board of Directors may make such special rules and  regulations  with respect to
such bank accounts, not inconsistent with the provisions of these By-Laws, as it
may deem expedient. For the purpose of deposit and for the purpose of collection
for the  account of the  Corporation,  checks,  drafts and other  orders for the
payment  of money  which are  payable to the order of the  Corporation  shall be
endorsed,  assigned  and  delivered  by the  Treasurer  or such other  person or
persons and in such manner as may from time to time be  designated  by the Board
of Directors.

Section 4.05 Dividends. Dividends upon the stock of the Corporation,  subject to
the  provisions of the Restated  Certificate  of  Incorporation,  if any, may be
declared by the Board of Directors at any regular or special  meeting,  pursuant
to law. Such  declaration may be continuing or limited to a specific  payment or
distribution. Dividends may be paid in cash, in property, or in shares of stock,
subject to the provisions of the Restated Certificate of Incorporation.

Section  4.06  Fiscal  Year.  The fiscal  year of the  Corporation  shall be the
calendar year, unless otherwise fixed by resolution of the Board of Directors.


                                    ARTICLE V

                                  CAPITAL STOCK

Section 5.01  Certificates  of Stock.  Every holder of stock in the  Corporation
shall  be  entitled  to have a  certificate  signed  by,  or in the  name of the
Corporation  by, the Chairman of the Board of  Directors,  or the President or a
Vice  President,  and by the  Treasurer  or an  Assistant  Treasurer,  or by the
Secretary or an Assistant Secretary of the Corporation, certifying the number of
shares owned by such holder in the Corporation.


                                                                               9
<PAGE>


                                   ARTICLE VI

                                  SEAL; OFFICES

Section 6.01 Seal. The corporate  seal shall have inscribed  thereon the name of
the Corporation,  the year of its  incorporation  and the words "Corporate Seal,
Delaware."  The seal may be used by  causing  it or a  facsimile  thereof  to be
impressed or affixed or reproduced or otherwise.

Section 6.02 Offices. The Corporation may have offices at such other places both
within or outside the State of Delaware as the Board of Directors  may from time
to time determine or as the business of the Corporation may require.


                                   ARTICLE VII

                                 INDEMNIFICATION

Section 7.01 Indemnification.  (a) No director of the Corporation shall have any
personal  liability to the Corporation or its  stockholders for monetary damages
for breach of fiduciary duty as a director,  provided that this provision  shall
not  eliminate  or limit the  liability  of a director (i) for any breach of the
director's duty of loyalty to the Corporation or its stockholders, (ii) for acts
or omissions  not in good faith or which  involve  intentional  misconduct  or a
knowing violation of law, (iii) under Section 174 of the General Corporation Law
of the State of Delaware,  or (iv) for any  transaction  from which the director
derived an improper personal benefit.

     (b) Each  person who was or is made a party or is  threatened  to be made a
party to or is  involved  in any  action,  suit or  proceeding,  whether  civil,
criminal,  administrative  or  investigative  (hereinafter a  "proceeding"),  by
reason  of the  fact  that  he or she is or was a  director  or  officer  of the
Corporation or is or was serving at the request of the Corporation as a director
or officer of another corporation or of a partnership,  joint venture,  trust or
other  enterprise,  including  service with respect to employee  benefit  plans,
whether the basis of such  proceeding  is alleged  action  either in an official
capacity as a director or officer or in any other  capacity  while  serving as a
director or officer,  shall be indemnified  and held harmless by the Corporation
to the fullest extent authorized by the General  Corporation Law of the State of
Delaware,  as the same exists or may  hereafter be amended  (but, in the case of
any  such  amendment,  only  to the  extent  that  such  amendment  permits  the
Corporation to provide  broader  indemnification  rights than said law permitted
the  Corporation  to provide  prior to such  amendment),  against all  expenses,
liability and loss (including  attorneys' fees,  judgments,  fines, excise taxes
pursuant to the Employee  Retirement Income Security Act of 1974, as amended, or
penalties and amounts paid or to be paid in settlement)  reasonably  incurred or
suffered by such person in connection therewith and such  indemnification  shall
continue  as to a person who has ceased to be a  director  or officer  and shall
inure to the benefit of his or her heirs,

                                                                              10
<PAGE>

executors and  administrators;  provided,  however,  that, the Corporation shall
indemnify  any  such  person  seeking   indemnification  in  connection  with  a
proceeding  (or part thereof)  initiated by such person only if such  proceeding
(or part thereof) was  authorized by the Board of Directors of the  Corporation.
The right to be  indemnified  conferred in this Section 7.01 shall be a contract
right and shall  include the right to be paid by the  Corporation  the  expenses
incurred in defending any such  proceeding in advance of its final  disposition;
provided,  however,  that, the payment of such expenses incurred by the director
or officer in his or her capacity as a director or officer (and not in any other
capacity  in which  service  was or is to be  rendered  by such  person  while a
director  or  officer,  including,  without  limitation,  service to an employee
benefit plan), in advance of the final disposition of proceeding,  shall be made
only upon delivery to the Corporation of an undertaking, by or on behalf of such
director or officer,  to repay all amounts so advanced if it shall ultimately be
determined that such director or officer is not entitled to be indemnified under
this Article or  otherwise.  The  Corporation  may, by action of its  Directors,
provide indemnification to employees and agents of the Corporation with the same
scope and effect as the foregoing indemnification of directors and officers.

     (c) The  indemnification  provided by this  Section 7.01 shall not limit or
exclude any rights,  indemnities or limitations of liability to which any person
may be entitled,  whether as a matter of law, under the Restated  Certificate of
Incorporation  of the  Corporation,  by agreement,  vote of the  stockholders or
disinterested directors of the Corporation or otherwise.

     (d) If a claim under paragraph (b) of this Section 7.01 is not paid in full
by the  Corporation  within  sixty  (60)  days  after a  written  claim has been
received by the Corporation,  the claimant may at any time thereafter bring suit
against  the  Corporation  to  recover  the unpaid  amount of the claim and,  if
successful in whole or in part,  the claimant  shall be entitled to be paid also
the expense of prosecuting  such claim. It shall be a defense to any such action
(other  than an action  brought  to  enforce a claim for  expenses  incurred  in
defending any proceeding in advance of its final  disposition where the required
undertaking,  if any is required, has been tendered to the Corporation) that the
claimant has not met the  standards of conduct which make it  permissible  under
the General  Corporation  Law of the State of Delaware  for the  Corporation  to
indemnify  the claimant for the amount  claimed,  but the burden of proving such
defense  shall be on the  Corporation.  Neither the  failure of the  Corporation
(including its Board,  independent  legal counsel,  or its stockholders) to have
made  a   determination   prior  to  the   commencement   of  such  action  that
indemnification of the claimant is proper in the circumstances because he or she
has met the applicable  standard or conduct set forth in the General Corporation
Law of the State of Delaware,  nor an actual  determination  by the  Corporation
(including its Board,  independent legal counsel,  or its stockholders) that the
claimant  has not met  such  applicable  standard  of  conduct,  shall  create a
presumption that the claimant has not met the applicable standard of conduct.

         (e) The Corporation may maintain insurance,  at its expense, to protect
itself  and any  director,  officer,  employee  or agent of the  corporation  or
another  corporation, 

                                                                              11
<PAGE>

partnership,  joint venture, trust or other enterprise against any such expense,
liability  or loss,  whether  or not the  Corporation  would  have the  power to
indemnify such person against such expense,  liability or loss under the General
Corporation Law of the State of Delaware.


                                  ARTICLE VIII

                                   AMENDMENTS

Section 8.01  Amendments.  These By-Laws may only be altered or repealed and new
By- Laws adopted by resolution of the Board of Directors.


                                                                              12



================================================================================


                                RIGHTS AGREEMENT

                                ----------------


                                  COVANCE INC.

                                       and

                          HARRIS TRUST AND SAVINGS BANK


                                  Rights Agent

                                ----------------


                          Dated as of December 31, 1996



================================================================================
<PAGE>


                                TABLE OF CONTENTS
                                                                           Page

Section 1.             Certain Definitions...................................1

Section 2.             Appointment of Rights Agent...........................3

Section 3.             Issue of Right Certificates...........................3

Section 4.             Form of Right Certificates............................5

Section 5.             Countersignature and Registration.....................5

Section 6.             Transfer, Split Up, Combination and
                           Exchange of Right Certificates;
                           Mutilated, Destroyed, Lost or
                           Stolen Right Certificates.........................6

Section 7.             Exercise of Rights; Purchase Price;
                           Expiration Date of Rights.........................7

Section 8.             Cancellation and Destruction of
                           Right Certificates................................7

Section 9.             Availability of Preferred Shares......................8

Section 10.            Preferred Shares Record Date..........................8

Section 11.            Adjustment of Purchase Price, Number of
                           Shares or Number of Rights........................8

Section 12.            Certificate of Adjusted Purchase Price
                           or Number of Shares...............................14
<PAGE>

                                                                           Page

Section 13.            Consolidation, Merger or Sale or Transfer
                           of Assets or Earning Power........................14

Section 14.            Fractional Rights and Fractional Shares...............15

Section 15.            Rights of Action......................................16

Section 16.            Agreement of Right Holders............................17

Section 17.            Right Certificate Holder Not Deemed a
                           Stockholder.......................................17

Section 18.            Concerning the Rights Agent...........................17

Section 19.            Merger or Consolidation or Change of
                           Name of Rights Agent..............................18

Section 20.            Duties of Rights Agent................................18

Section 21.            Change of Rights Agent................................20

Section 22.            Issuance of New Right Certificates....................21

Section 23.            Redemption............................................21

Section 24.            Exchange..............................................21

Section 25.            Notice of Certain Events..............................23

Section 26.            Notices...............................................23

Section 27.            Supplements and Amendments............................24

Section 28.            Successors............................................24

Section 29.            Benefits of this Agreement............................24


<PAGE>

                                                                           Page

Section 30.            Severability..........................................25

Section 31.            Governing Law.........................................25

Section 32.            Counterparts..........................................25

Section 33.            Descriptive Headings..................................25

Signatures...................................................................25

Exhibit A - Form of Right Certificate
Exhibit B - Form of Summary of Rights to Purchase Preferred Shares

<PAGE>

         AGREEMENT,  dated as of December  31,  1996,  between  Covance  Inc., a
Delaware  corporation  (the  "Company"),  and Harris Trust and Savings Bank (the
"Rights Agent").

         The Board of  Directors  of the Company has  authorized  and declared a
dividend of one preferred share purchase right (a "Right") for each Common Share
(as  hereinafter  defined) of the Company  outstanding on December 31, 1996 (the
"Record Date"),  each Right representing the right to purchase one one-hundredth
of a Preferred Share (as hereinafter defined), upon the terms and subject to the
conditions  herein  set forth,  and has  further  authorized  and  directed  the
issuance  of one Right with  respect  to each  Common  Share  that shall  become
outstanding  between the Record Date and the earliest of the Distribution  Date,
the Redemption Date and the Final Expiration Date (as such terms are hereinafter
defined).

         Accordingly, in consideration of the premises and the mutual agreements
herein set forth, the parties hereby agree as follows:

         Section 1. Certain  Definitions.  For purposes of this  Agreement,  the
following terms have the meanings indicated:

         (a)  "Acquiring  Person"  shall  mean  any  Person  (as  such  term  is
hereinafter  defined) who or which,  together with all Affiliates and Associates
(as such terms are hereinafter  defined) of such Person, shall be the Beneficial
Owner (as such term is hereinafter  defined) of 20% or more of the Common Shares
of the  Company  then  outstanding,  but  shall not  include  the  Company,  any
Subsidiary  (as such term is hereinafter  defined) of the Company,  any employee
benefit  plan of the Company or any  Subsidiary  of the  Company,  or any entity
holding  Common  Shares  for  or  pursuant  to  the  terms  of  any  such  plan.
Notwithstanding  the foregoing,  no Person shall become an "Acquiring Person" as
the result of an acquisition of Common Shares by the Company which,  by reducing
the number of shares outstanding,  increases the proportionate  number of shares
beneficially  owned by such  Person to 20% or more of the  Common  Shares of the
Company then outstanding;  provided,  however, that if a Person shall become the
Beneficial  Owner  of 20% or more  of the  Common  Shares  of the  Company  then
outstanding  by reason of share  purchases by the Company and shall,  after such
share  purchases by the Company,  become the Beneficial  Owner of any additional
Common  Shares  of the  Company,  then  such  Person  shall be  deemed  to be an
"Acquiring Person".  Notwithstanding the foregoing, if the Board of Directors of
the Company  determines  in good faith that a Person who would  otherwise  be an
"Acquiring  Person",  as defined  pursuant to the  foregoing  provisions of this
paragraph  (a),  has  become  such  inadvertently,  and such  Person  divests as
promptly as practicable a sufficient number of Common Shares so that such Person
would no longer be an "Acquiring  Person," as defined  pursuant to the foregoing
provisions of this  paragraph (a), then such Person shall not be deemed to be an
"Acquiring Person" for any purposes of this Agreement.

         (b)  "Affiliate"  and  "Associate"  shall have the respective  meanings
ascribed to such terms in Rule 12b-2 of the General Rules and Regulations  under
the  Securities  Exchange Act of 1934, as amended (the  "Exchange  Act"),  as in
effect on the date of this Agreement.

<PAGE>

         (c) A Person  shall be deemed  the  "Beneficial  Owner" of and shall be
deemed to "beneficially own" any securities:

         (i) which such Person or any of such Person's  Affiliates or Associates
     beneficially owns, directly or indirectly;

         (ii) which such Person or any of such Person's Affiliates or Associates
     has (A) the right to acquire (whether such right is exercisable immediately
     or only after the passage of time) pursuant to any  agreement,  arrangement
     or  understanding   (other  than  customary  agreements  with  and  between
     underwriters  and selling  group members with respect to a bona fide public
     offering  of  securities),  or upon  the  exercise  of  conversion  rights,
     exchange rights, rights (other than these Rights),  warrants or options, or
     otherwise;  provided,  however,  that a  Person  shall  not be  deemed  the
     Beneficial Owner of, or to beneficially own,  securities  tendered pursuant
     to a tender or exchange offer made by or on behalf of such Person or any of
     such Person's  Affiliates or Associates until such tendered  securities are
     accepted for purchase or exchange; or (B) the right to vote pursuant to any
     agreement,  arrangement or understanding;  provided, however, that a Person
     shall not be deemed the Beneficial  Owner of, or to  beneficially  own, any
     security  if the  agreement,  arrangement  or  understanding  to vote  such
     security (1) arises solely from a revocable  proxy or consent given to such
     Person in response to a public proxy or consent  solicitation made pursuant
     to,  and  in  accordance   with,  the  applicable   rules  and  regulations
     promulgated  under the Exchange Act and (2) is not also then  reportable on
     Schedule  13D  under  the  Exchange  Act (or any  comparable  or  successor
     report); or

         (iii) which are  beneficially  owned,  directly or  indirectly,  by any
     other Person with which such Person or any of such  Person's  Affiliates or
     Associates has any  agreement,  arrangement  or  understanding  (other than
     customary  agreements  with and  between  underwriters  and  selling  group
     members with respect to a bona fide public  offering of securities) for the
     purpose of acquiring, holding, voting (except to the extent contemplated by
     the proviso to Section  1(c)(ii)(B))  or disposing of any securities of the
     Company.

         Notwithstanding  anything in this definition of Beneficial Ownership to
the  contrary,  the phrase  "then  outstanding,"  when used with  reference to a
Person's  Beneficial  Ownership of  securities  of the  Company,  shall mean the
number of such securities  then issued and outstanding  together with the number
of such securities not then actually  issued and  outstanding  which such Person
would be deemed to own beneficially hereunder.

         (d) "Business Day" shall mean any day other than a Saturday,  a Sunday,
or a day on which banking  institutions  in State of Delaware are  authorized or
obligated by law or executive order to close.

<PAGE>

         (e) "Close of business" on any given date shall mean 5:00 P.M., Chicago
time, on such date; provided,  however,  that if such date is not a Business Day
it shall mean 5:00 P.M., Chicago time, on the next succeeding Business Day.

         (f) "Common  Shares" when used with reference to the Company shall mean
the shares of common stock,  par value $.01 per share,  of the Company.  "Common
Shares" when used with reference to any Person other than the Company shall mean
the capital stock (or equity  interest)  with the greatest  voting power of such
other  Person or, if such other Person is a Subsidiary  of another  Person,  the
Person or Persons which ultimately control such first-mentioned Person.

         (g)  "Distribution  Date" shall have the meaning set forth in Section 3
hereof.

         (h) "Final Expiration Date" shall have the meaning set forth in Section
7 hereof.

         (i) "Person"  shall mean any  individual,  firm,  corporation  or other
entity, and shall include any successor (by merger or otherwise) of such entity.

         (j)   "Preferred   Shares"   shall  mean  shares  of  Series  A  Junior
Participating Preferred Stock, par value $1.00 per share, of the Company.

         (k)  "Redemption  Date"  shall have the  meaning set forth in Section 7
hereof.

         (l)  "Shares  Acquisition  Date"  shall  mean the first  date of public
announcement by the Company or an Acquiring  Person that an Acquiring Person has
become such.

         (m)  "Subsidiary"  of any Person  shall mean any  corporation  or other
entity of which a majority of the voting power of the voting  equity  securities
or equity interest is owned, directly or indirectly, by such Person.

         Section 2. Appointment of Rights Agent. The Company hereby appoints the
Rights Agent to act as agent for the Company and the holders of the Rights (who,
in accordance with Section 3 hereof,  shall prior to the Distribution  Date also
be the holders of the Common Shares) in accordance with the terms and conditions
hereof,  and the Rights Agent hereby accepts such  appointment.  The Company may
from time to time  appoint  such  co-Rights  Agents as it may deem  necessary or
desirable.

         Section 3. Issue of Right  Certificates.  (a) Until the  earlier of (i)
the tenth day after the Shares  Acquisition  Date or (ii) the tenth business day
(or such later  date as may be  determined  by action of the Board of  Directors
prior to such time as any Person becomes an Acquiring  Person) after the date of
the  commencement  by any Person (other than the Company,  any Subsidiary of the
Company,  any employee  benefit plan of the Company or of any  Subsidiary of the
Company or any entity  holding Common Shares for or pursuant to the terms of any
such  plan) of, or of the first  public  announcement  of the  intention  of any
Person

<PAGE>

(other than the Company,  any  Subsidiary of the Company,  any employee  benefit
plan of the Company or of any  Subsidiary  of the Company or any entity  holding
Common  Shares for or  pursuant  to the terms of any such plan) to  commence,  a
tender or exchange  offer the  consummation  of which would result in any Person
becoming the Beneficial  Owner of Common Shares  aggregating  20% or more of the
then outstanding  Common Shares (including any such date which is after the date
of this  Agreement and prior to the issuance of the Rights;  the earlier of such
dates being herein referred to as the "Distribution  Date"), (x) the Rights will
be  evidenced  (subject  to  the  provisions  of  Section  3(b)  hereof)  by the
certificates  for Common Shares  registered in the names of the holders  thereof
(which  certificates  shall also be deemed to be Right  Certificates) and not by
separate  Right  Certificates,  and (y) the right to receive Right  Certificates
will be transferable  only in connection with the transfer of Common Shares.  As
soon as practicable  after the  Distribution  Date, the Company will prepare and
execute,  the Rights Agent will countersign,  and the Company will send or cause
to be sent (and the Rights  Agent  will,  if  requested,  send) by  first-class,
insured,  postage-prepaid mail, to each record holder of Common Shares as of the
close of business on the Distribution  Date, at the address of such holder shown
on the records of the Company, a Right Certificate, in substantially the form of
Exhibit A hereto (a "Right  Certificate"),  evidencing one Right for each Common
Share so held. As of the Distribution  Date, the Rights will be evidenced solely
by such Right Certificates.

         (b) On the  Record  Date,  or as soon as  practicable  thereafter,  the
Company will send a copy of a Summary of Rights to Purchase Preferred Shares, in
substantially  the form of  Exhibit  B hereto  (the  "Summary  of  Rights"),  by
first-class,  postage-prepaid mail, to each record holder of Common Shares as of
the close of business on the Record Date, at the address of such holder shown on
the records of the  Company.  With  respect to  certificates  for Common  Shares
outstanding as of the Record Date, until the Distribution  Date, the Rights will
be evidenced by such certificates registered in the names of the holders thereof
together  with a copy of the  Summary  of  Rights  attached  thereto.  Until the
Distribution Date (or the earlier of the Redemption Date or the Final Expiration
Date),  the  surrender  for  transfer  of  any  certificate  for  Common  Shares
outstanding on the Record Date,  with or without a copy of the Summary of Rights
attached  thereto,  shall also constitute the transfer of the Rights  associated
with the Common Shares represented thereby.

         (c) Certificates for Common Shares which become outstanding (including,
without limitation, reacquired Common Shares referred to in the last sentence of
this  paragraph  (c)) after the  Record  Date but prior to the  earliest  of the
Distribution  Date, the Redemption Date or the Final  Expiration Date shall have
impressed on, printed on, written on or otherwise  affixed to them the following
legend:

     This  certificate  also evidences and entitles the holder hereof to certain
     rights as set forth in a Rights  Agreement  between Covance Inc. and Harris
     Trust  and  Savings  Bank,  dated as of  December  31,  1996  (the  "Rights
     Agreement"), the terms of which are hereby incorporated herein by reference
     and a copy of  which  is on  file at the  principal  executive  offices  of
     Covance  Inc.  Under  certain  circumstances,  as set  forth in the  Rights
     Agreement,  such Rights will be evidenced by separate certificates and will
     no

<PAGE>

     longer be evidenced  by this  certificate.  Covance  Inc.  will mail to the
     holder of this  certificate a copy of the Rights  Agreement  without charge
     after receipt of a written request therefor.  Under certain  circumstances,
     as set forth in the  Rights  Agreement,  Rights  issued to any  Person  who
     becomes an Acquiring Person (as defined in the Rights Agreement) may become
     null and void.


With respect to such  certificates  containing the foregoing  legend,  until the
Distribution  Date, the Rights associated with the Common Shares  represented by
such  certificates  shall  be  evidenced  by such  certificates  alone,  and the
surrender  for  transfer  of any such  certificate  shall  also  constitute  the
transfer of the Rights associated with the Common Shares represented thereby. In
the event that the Company  purchases  or acquires  any Common  Shares after the
Record Date but prior to the Distribution  Date, any Rights associated with such
Common  Shares shall be deemed  cancelled  and retired so that the Company shall
not be entitled to exercise any Rights  associated  with the Common Shares which
are no longer outstanding.

         Section 4. Form of Right Certificates.  The Right Certificates (and the
forms of election to purchase  Preferred  Shares and of assignment to be printed
on the reverse thereof) shall be substantially  the same as Exhibit A hereto and
may have such marks of identification or designation and such legends, summaries
or endorsements  printed thereon as the Company may deem  appropriate and as are
not inconsistent with the provisions of this Agreement, or as may be required to
comply with any  applicable  law or with any rule or  regulation  made  pursuant
thereto or with any rule or regulation of any stock exchange on which the Rights
may  from  time to time be  listed,  or to  conform  to  usage.  Subject  to the
provisions  of Section 22  hereof,  the Right  Certificates  shall  entitle  the
holders  thereof to purchase  such number of one  one-hundredths  of a Preferred
Share as shall be set forth  therein  at the price  per one  one-hundredth  of a
Preferred Share set forth therein (the "Purchase Price"), but the number of such
one  one-hundredths of a Preferred Share and the Purchase Price shall be subject
to adjustment as provided herein.

         Section 5.  Countersignature  and Registration.  The Right Certificates
shall be  executed on behalf of the  Company by its  Chairman of the Board,  its
Vice Chairman,  its Chief  Executive  Officer,  its  President,  any of its Vice
Presidents, or its Treasurer,  either manually or by facsimile signature,  shall
have affixed  thereto the Company's  seal or a facsimile  thereof,  and shall be
attested by the  Secretary  or an Assistant  Secretary  of the  Company,  either
manually or by facsimile  signature.  The Right  Certificates  shall be manually
countersigned  by the Rights Agent and shall not be valid for any purpose unless
countersigned.  In case any  officer of the Company who shall have signed any of
the Right  Certificates  shall cease to be such  officer of the  Company  before
countersignature  by the Rights  Agent and issuance and delivery by the Company,
such Right Certificates,  nevertheless, may be countersigned by the Rights Agent
and issued and delivered by the Company with the same force and effect as though
the person who signed such Right  Certificates had not ceased to be such officer
of the Company; and any Right Certificate may be signed on behalf of the Company
by  any  person  who,  at the  actual  date  of  the  execution  of  such  Right
Certificate, shall be a proper officer of

<PAGE>

the  Company  to  sign  such  Right  Certificate,  although  at the  date of the
execution of this Rights Agreement any such person was not such an officer.

         Following the Distribution Date, the Rights Agent will keep or cause to
be kept, at its principal  office,  books for  registration  and transfer of the
Right  Certificates  issued  hereunder.  Such  books  shall  show the  names and
addresses of the  respective  holders of the Right  Certificates,  the number of
Rights  evidenced on its face by each of the Right  Certificates and the date of
each of the Right Certificates.

         Section  6.  Transfer,  Split Up,  Combination  and  Exchange  of Right
Certificates;  Mutilated, Destroyed, Lost or Stolen Right Certificates.  Subject
to the provisions of Section 14 hereof,  at any time after the close of business
on the  Distribution  Date,  and at or prior to the  close  of  business  on the
earlier  of the  Redemption  Date  or  the  Final  Expiration  Date,  any  Right
Certificate or Right Certificates  (other than Right  Certificates  representing
Rights that have become void pursuant to Section  11(a)(ii)  hereof or that have
been  exchanged  pursuant  to Section 24 hereof) may be  transferred,  split up,
combined or  exchanged  for another  Right  Certificate  or Right  Certificates,
entitling the registered holder to purchase a like number of one  one-hundredths
of a Preferred Share as the Right Certificate or Right Certificates  surrendered
then  entitled  such  holder to  purchase.  Any  registered  holder  desiring to
transfer,  split  up,  combine  or  exchange  any  Right  Certificate  or  Right
Certificates  shall make such request in writing  delivered to the Rights Agent,
and  shall  surrender  the  Right  Certificate  or  Right   Certificates  to  be
transferred,  split up,  combined or  exchanged at the  principal  office of the
Rights Agent.  Thereupon,  the Rights Agent shall countersign and deliver to the
person entitled thereto a Right Certificate or Right  Certificates,  as the case
may be, as so requested.  The Company may require payment of a sum sufficient to
cover any tax or governmental  charge that may be imposed in connection with any
transfer, split up, combination or exchange of Right Certificates.

         Upon receipt by the Company and the Rights Agent of evidence reasonably
satisfactory  to them of the loss,  theft,  destruction or mutilation of a Right
Certificate,  and,  in case of  loss,  theft or  destruction,  of  indemnity  or
security  reasonably  satisfactory  to  them,  and,  at the  Company's  request,
reimbursement  to the Company and the Rights  Agent of all  reasonable  expenses
incidental  thereto,  and upon surrender to the Rights Agent and cancellation of
the Right  Certificate  if  mutilated,  the Company  will make and deliver a new
Right  Certificate  of like  tenor  to the  Rights  Agent  for  delivery  to the
registered holder in lieu of the Right Certificate so lost, stolen, destroyed or
mutilated.

         Section 7.  Exercise  of Rights;  Purchase  Price;  Expiration  Date of
Rights.  (a) The  registered  holder of any Right  Certificate  may exercise the
Rights  evidenced  thereby (except as otherwise  provided herein) in whole or in
part at any time  after  the  Distribution  Date  upon  surrender  of the  Right
Certificate,  with the form of election to purchase on the reverse  side thereof
duly executed,  to the Rights Agent at the principal office of the Rights Agent,
together  with payment of the  Purchase  Price for each one  one-hundredth  of a
Preferred  Share  as to  which  the  Rights  are  exercised,  at or prior to the
earliest  of (i) the  close  of  business  on  December  31,  2006  (the  "Final
Expiration Date"), (ii) the time at which the Rights are

<PAGE>

redeemed as provided in Section 23 hereof (the "Redemption  Date"), or (iii) the
time at which such Rights are exchanged as provided in Section 24 hereof.

         (b) The Purchase Price for each one  one-hundredth of a Preferred Share
purchasable  pursuant to the exercise of a Right shall  initially  be $100,  and
shall be subject to adjustment from time to time as provided in Section 11 or 13
hereof and shall be payable in lawful  money of the United  States of America in
accordance with paragraph (c) below.

         (c)  Upon  receipt  of a  Right  Certificate  representing  exercisable
Rights,  with the form of election to purchase  duly  executed,  accompanied  by
payment of the Purchase Price for the shares to be purchased and an amount equal
to any  applicable  transfer tax required to be paid by the holder of such Right
Certificate in accordance  with Section 9 hereof by certified  check,  cashier's
check or money order payable to the order of the Company, the Rights Agent shall
thereupon  promptly (i) (A) requisition from any transfer agent of the Preferred
Shares  certificates  for the number of Preferred Shares to be purchased and the
Company hereby irrevocably authorizes its transfer agent to comply with all such
requests,  or (B)  requisition  from the depositary  agent  depositary  receipts
representing such number of one one-hundredths of a Preferred Share as are to be
purchased (in which case  certificates for the Preferred  Shares  represented by
such  receipts  shall be  deposited by the  transfer  agent with the  depositary
agent) and the Company hereby  directs the depositary  agent to comply with such
request, (ii) when appropriate,  requisition from the Company the amount of cash
to be paid in lieu of issuance of fractional  shares in accordance  with Section
14 hereof,  (iii) after receipt of such  certificates  or  depositary  receipts,
cause the same to be delivered to or upon the order of the registered  holder of
such Right Certificate, registered in such name or names as may be designated by
such holder and (iv) when  appropriate,  after receipt,  deliver such cash to or
upon the order of the registered holder of such Right Certificate.

         (d) In case  the  registered  holder  of any  Right  Certificate  shall
exercise less than all the Rights  evidenced  thereby,  a new Right  Certificate
evidencing Rights equivalent to the Rights remaining unexercised shall be issued
by the Rights Agent to the registered holder of such Right Certificate or to his
duly authorized assigns, subject to the provisions of Section 14 hereof.

         Section 8.  Cancellation  and  Destruction of Right  Certificates.  All
Right Certificates surrendered for the purpose of exercise,  transfer, split up,
combination  or exchange  shall,  if surrendered to the Company or to any of its
agents,  be delivered to the Rights Agent for cancellation or in cancelled form,
or, if surrendered  to the Rights Agent,  shall be cancelled by it, and no Right
Certificates  shall be issued in lieu thereof  except as expressly  permitted by
any of the provisions of this Rights Agreement. The Company shall deliver to the
Rights  Agent for  cancellation  and  retirement,  and the Rights Agent shall so
cancel and retire,  any other  Right  Certificate  purchased  or acquired by the
Company otherwise than upon the exercise thereof. The Rights Agent shall deliver
all  cancelled  Right  Certificates  to the  Company,  or shall,  at the written
request of the Company,  destroy such cancelled Right Certificates,  and in such
case shall deliver a certificate of destruction thereof to the Company.

<PAGE>

         Section 9. Availability of Preferred Shares.  The Company covenants and
agrees  that  it  will  cause  to be  reserved  and  kept  available  out of its
authorized  and unissued  Preferred  Shares or any Preferred  Shares held in its
treasury,  the number of Preferred  Shares that will be sufficient to permit the
exercise in full of all  outstanding  Rights in  accordance  with Section 7. The
Company  covenants  and  agrees  that it will  take  all such  action  as may be
necessary to ensure that all Preferred  Shares delivered upon exercise of Rights
shall,  at the time of delivery of the  certificates  for such Preferred  Shares
(subject to payment of the Purchase Price),  be duly and validly  authorized and
issued and fully paid and nonassessable shares.

         The Company further  covenants and agrees that it will pay when due and
payable any and all federal and state  transfer  taxes and charges  which may be
payable in respect of the issuance or delivery of the Right  Certificates  or of
any  Preferred  Shares  upon the  exercise  of Rights.  The  Company  shall not,
however,  be required to pay any transfer tax which may be payable in respect of
any transfer or delivery of Right  Certificates  to a person other than,  or the
issuance or delivery of  certificates  or depositary  receipts for the Preferred
Shares  in a name  other  than  that of,  the  registered  holder  of the  Right
Certificate evidencing Rights surrendered for exercise or to issue or to deliver
any  certificates or depositary  receipts for Preferred Shares upon the exercise
of any  Rights  until  any such tax  shall  have  been  paid (any such tax being
payable by the holder of such Right  Certificate  at the time of  surrender)  or
until it has been established to the Company's  reasonable  satisfaction that no
such tax is due.

         Section 10. Preferred Shares Record Date. Each person in whose name any
certificate for Preferred Shares is issued upon the exercise of Rights shall for
all  purposes  be deemed to have  become the  holder of record of the  Preferred
Shares  represented  thereby on, and such  certificate  shall be dated, the date
upon which the Right Certificate evidencing such Rights was duly surrendered and
payment of the  Purchase  Price (and any  applicable  transfer  taxes) was made;
provided, however, that if the date of such surrender and payment is a date upon
which the Preferred Shares transfer books of the Company are closed, such person
shall be deemed to have  become  the record  holder of such  shares on, and such
certificate  shall be  dated,  the next  succeeding  Business  Day on which  the
Preferred  Shares transfer books of the Company are open.  Prior to the exercise
of the Rights evidenced thereby,  the holder of a Right Certificate shall not be
entitled  to any  rights of a holder of  Preferred  Shares  for which the Rights
shall be  exercisable,  including,  without  limitation,  the right to vote,  to
receive dividends or other  distributions or to exercise any preemptive  rights,
and shall not be  entitled  to  receive  any  notice of any  proceedings  of the
Company, except as provided herein.

         Section 11. Adjustment of Purchase Price, Number of Shares or Number of
Rights. The Purchase Price, the number of Preferred Shares covered by each Right
and the number of Rights outstanding are subject to adjustment from time to time
as provided in this Section 11.

         (a) (i) In the event the  Company  shall at any time  after the date of
this  Agreement  (A)  declare a  dividend  on the  Preferred  Shares  payable in
Preferred Shares,  (B) subdivide the outstanding  Preferred Shares,  (C) combine
the outstanding  Preferred  Shares into

<PAGE>

a smaller  number of  Preferred  Shares or (D) issue any  shares of its  capital
stock  in a  reclassification  of  the  Preferred  Shares  (including  any  such
reclassification  in  connection  with a  consolidation  or  merger in which the
Company  is the  continuing  or  surviving  corporation),  except  as  otherwise
provided in this Section 11(a),  the Purchase Price in effect at the time of the
record date for such  dividend  or of the  effective  date of such  subdivision,
combination  or  reclassification,  and the number and kind of shares of capital
stock  issuable  on such date,  shall be  proportionately  adjusted  so that the
holder of any Right  exercised  after such time shall be entitled to receive the
aggregate  number and kind of shares of capital  stock which,  if such Right had
been exercised  immediately  prior to such date and at a time when the Preferred
Shares  transfer  books of the Company were open,  he would have owned upon such
exercise and been entitled to receive by virtue of such  dividend,  subdivision,
combination or reclassification;  provided,  however, that in no event shall the
consideration  to be paid  upon  the  exercise  of one  Right  be less  than the
aggregate par value of the shares of capital stock of the Company  issuable upon
exercise of one Right.

         (ii) Subject to Section 24 of this  Agreement,  in the event any Person
becomes an  Acquiring  Person,  each holder of a Right shall  thereafter  have a
right to receive,  upon  exercise  thereof at a price equal to the then  current
Purchase  Price  multiplied by the number of one  one-hundredths  of a Preferred
Share for which a Right is then  exercisable,  in  accordance  with the terms of
this Agreement and in lieu of Preferred Shares,  such number of Common Shares of
the  Company as shall  equal the result  obtained  by (x)  multiplying  the then
current Purchase Price by the number of one  one-hundredths of a Preferred Share
for which a Right is then  exercisable  and dividing  that product by (y) 50% of
the  then  current  per  share  market  price  of the  Company's  Common  Shares
(determined  pursuant to Section 11(d) hereof) on the date of the  occurrence of
such event.  In the event that any Person shall  become an Acquiring  Person and
the Rights  shall then be  outstanding,  the  Company  shall not take any action
which would  eliminate or diminish  the benefits  intended to be afforded by the
Rights.

         From and after the  occurrence  of such  event,  any Rights that are or
were acquired or beneficially owned by any Acquiring Person (or any Associate or
Affiliate of such Acquiring  Person) shall be void and any holder of such Rights
shall  thereafter  have no right to exercise  such Rights under any provision of
this Agreement.  No Right Certificate shall be issued pursuant to Section 3 that
represents Rights  beneficially  owned by an Acquiring Person whose Rights would
be void  pursuant  to the  preceding  sentence  or any  Associate  or  Affiliate
thereof;  no Right  Certificate shall be issued at any time upon the transfer of
any Rights to an Acquiring  Person  whose  Rights would be void  pursuant to the
preceding  sentence or any  Associate or Affiliate  thereof or to any nominee of
such  Acquiring  Person,  Associate  or  Affiliate;  and any  Right  Certificate
delivered to the Rights  Agent for transfer to an Acquiring  Person whose Rights
would be void pursuant to the preceding sentence shall be cancelled.

         (iii) In the event that there  shall not be  sufficient  Common  Shares
issued but not  outstanding or authorized but unissued to permit the exercise in
full of the Rights in  accordance  with the  foregoing  subparagraph  (ii),  the
Company  shall take all such action as may be necessary to authorize  additional
Common Shares for issuance upon exercise of the Rights. In the event the Company
shall,  after good  faith  effort,  be unable to take all such

<PAGE>

action as may be necessary to  authorize  such  additional  Common  Shares,  the
Company shall substitute, for each Common Share that would otherwise be issuable
upon exercise of a Right, a number of Preferred  Shares or fraction thereof such
that the current per share market price of one  Preferred  Share  multiplied  by
such number or fraction  is equal to the current per share  market  price of one
Common  Share as of the date of  issuance of such  Preferred  Shares or fraction
thereof.

         (b) In case the  Company  shall fix a record  date for the  issuance of
rights,  options or warrants to all holders of Preferred  Shares  entitling them
(for a period  expiring  within 45  calendar  days  after such  record  date) to
subscribe  for or purchase  Preferred  Shares (or shares having the same rights,
privileges  and  preferences  as the  Preferred  Shares  ("equivalent  preferred
shares"))  or  securities   convertible  into  Preferred  Shares  or  equivalent
preferred  shares at a price per Preferred  Share or equivalent  preferred share
(or  having a  conversion  price  per  share,  if a  security  convertible  into
Preferred Shares or equivalent  preferred shares) less than the then current per
share market price of the Preferred Shares (as defined in Section 11(d)) on such
record date,  the Purchase Price to be in effect after such record date shall be
determined by multiplying the Purchase Price in effect immediately prior to such
record  date by a  fraction,  the  numerator  of which  shall be the  number  of
Preferred  Shares  outstanding  on such record date plus the number of Preferred
Shares  which the  aggregate  offering  price of the total  number of  Preferred
Shares and/or equivalent preferred shares so to be offered (and/or the aggregate
initial  conversion price of the convertible  securities so to be offered) would
purchase at such current market price and the  denominator of which shall be the
number of Preferred  Shares  outstanding  on such record date plus the number of
additional Preferred Shares and/or equivalent preferred shares to be offered for
subscription  or purchase  (or into which the  convertible  securities  so to be
offered are initially  convertible);  provided,  however, that in no event shall
the  consideration  to be paid upon the  exercise  of one Right be less than the
aggregate par value of the shares of capital stock of the Company  issuable upon
exercise  of one  Right.  In  case  such  subscription  price  may be  paid in a
consideration part or all of which shall be in a form other than cash, the value
of such  consideration  shall be as  determined  in good  faith by the  Board of
Directors of the Company,  whose determination shall be described in a statement
filed with the Rights Agent.  Preferred  Shares owned by or held for the account
of the  Company  shall not be deemed  outstanding  for the  purpose  of any such
computation.  Such adjustment shall be made successively  whenever such a record
date is fixed; and in the event that such rights, options or warrants are not so
issued,  the  Purchase  Price shall be adjusted to be the  Purchase  Price which
would then be in effect if such record date had not been fixed.

         (c) In case the  Company  shall fix a record  date for the  making of a
distribution  to all  holders  of  the  Preferred  Shares  (including  any  such
distribution  made in  connection  with a  consolidation  or merger in which the
Company is the continuing or surviving corporation) of evidences of indebtedness
or assets (other than a regular quarterly cash dividend or a dividend payable in
Preferred Shares) or subscription  rights or warrants  (excluding those referred
to in Section  11(b)  hereof),  the  Purchase  Price to be in effect  after such
record date shall be  determined  by  multiplying  the Purchase  Price in effect
immediately  prior to such  record date by a fraction,  the  numerator  of which
shall be the then current per share market

<PAGE>

price of the  Preferred  Shares on such record date,  less the fair market value
(as  determined  in good faith by the Board of Directors  of the Company,  whose
determination  shall be described in a statement filed with the Rights Agent) of
the portion of the assets or evidences of  indebtedness  so to be distributed or
of such  subscription  rights or warrants  applicable to one Preferred Share and
the  denominator  of which shall be such  current per share  market price of the
Preferred Shares; provided, however, that in no event shall the consideration to
be paid upon the exercise of one Right be less than the  aggregate  par value of
the shares of capital  stock of the  Company to be issued  upon  exercise of one
Right. Such adjustments  shall be made successively  whenever such a record date
is fixed;  and in the event that such  distribution is not so made, the Purchase
Price shall again be  adjusted to be the  Purchase  Price which would then be in
effect if such record date had not been fixed.

         (d) (i) For the purpose of any computation hereunder,  the "current per
share  market  price" of any  security  (a  "Security"  for the  purpose of this
Section  11(d)(i))  on any date  shall be deemed to be the  average of the daily
closing  prices per share of such Security for the 30  consecutive  Trading Days
(as such term is hereinafter  defined) immediately prior to such date; provided,
however,  that in the  event  that the  current  per share  market  price of the
Security is determined  during a period following the announcement by the issuer
of such Security of (A) a dividend or distribution  on such Security  payable in
shares of such Security or securities  convertible into such shares,  or (B) any
subdivision,  combination or  reclassification of such Security and prior to the
expiration  of 30 Trading Days after the  ex-dividend  date for such dividend or
distribution,   or  the  record  date  for  such  subdivision,   combination  or
reclassification,  then,  and in each such case,  the current  per share  market
price shall be  appropriately  adjusted to reflect the current  market price per
share  equivalent of such Security.  The closing price for each day shall be the
last sale price,  regular way, or, in case no such sale takes place on such day,
the average of the closing bid and asked prices,  regular way, in either case as
reported in the principal consolidated transaction reporting system with respect
to securities  listed or admitted to trading on the New York Stock  Exchange or,
if the  Security  is not  listed or  admitted  to  trading on the New York Stock
Exchange, as reported in the principal consolidated transaction reporting system
with respect to securities listed on the principal national  securities exchange
on which the  Security is listed or  admitted to trading or, if the  Security is
not listed or admitted to trading on any national securities exchange,  the last
quoted  price or, if not so  quoted,  the  average of the high bid and low asked
prices in the  over-the-counter  market, as reported by the National Association
of Securities Dealers, Inc. Automated Quotations System ("NASDAQ") or such other
system  then in use,  or, if on any such date the  Security is not quoted by any
such organization,  the average of the closing bid and asked prices as furnished
by a professional  market maker making a market in the Security  selected by the
Board of Directors of the Company.  The term  "Trading  Day" shall mean a day on
which the principal national securities exchange on which the Security is listed
or  admitted  to  trading is open for the  transaction  of  business  or, if the
Security  is not  listed or  admitted  to  trading  on any  national  securities
exchange, a Business Day.

              (ii) For the purpose of any  computation  hereunder,  the "current
per  share  market  price"  of the  Preferred  Shares  shall  be  determined  in
accordance  with the  method  set forth in Section  11(d)(i).  If the  Preferred
Shares are not publicly  traded,  the  "current  per share

<PAGE>

market price" of the  Preferred  Shares shall be  conclusively  deemed to be the
current per share market price of the Common  Shares as  determined  pursuant to
Section  11(d)(i)  (appropriately  adjusted  to reflect any stock  split,  stock
dividend or similar transaction occurring after the date hereof),  multiplied by
one hundred.  If neither the Common Shares nor the Preferred Shares are publicly
held or so listed or traded,  "current  per share  market  price" shall mean the
fair value per share as  determined  in good faith by the Board of  Directors of
the Company,  whose  determination  shall be described in a statement filed with
the Rights Agent.

         (e) No adjustment in the Purchase  Price shall be required  unless such
adjustment  would require an increase or decrease of at least 1% in the Purchase
Price;  provided,  however, that any adjustments which by reason of this Section
11(e) are not  required  to be made  shall be  carried  forward  and taken  into
account in any subsequent  adjustment.  All  calculations  under this Section 11
shall be made to the  nearest  cent or to the  nearest  one  one-millionth  of a
Preferred  Share or one ten-  thousandth  of any other  share or security as the
case may be.  Notwithstanding  the first  sentence of this  Section  11(e),  any
adjustment  required by this  Section 11 shall be made no later than the earlier
of (i)  three  years  from  the  date of the  transaction  which  requires  such
adjustment  or (ii) the date of the  expiration  of the  right to  exercise  any
Rights.

         (f) If as a result of an  adjustment  made  pursuant  to Section  11(a)
hereof,  the holder of any Right  thereafter  exercised shall become entitled to
receive any shares of capital stock of the Company other than Preferred  Shares,
thereafter  the number of such other shares so  receivable  upon exercise of any
Right shall be subject to adjustment  from time to time in a manner and on terms
as nearly  equivalent  as  practicable  to the  provisions  with  respect to the
Preferred  Shares  contained in Section  11(a) through (c),  inclusive,  and the
provisions  of Sections  7, 9, 10 and 13 with  respect to the  Preferred  Shares
shall apply on like terms to any such other shares.

         (g) All  Rights  originally  issued by the  Company  subsequent  to any
adjustment  made to the Purchase  Price  hereunder  shall  evidence the right to
purchase,  at the adjusted Purchase Price, the number of one one-hundredths of a
Preferred  Share  purchasable  from time to time  hereunder upon exercise of the
Rights, all subject to further adjustment as provided herein.

         (h) Unless the Company shall have exercised its election as provided in
Section  11(i),  upon each  adjustment of the Purchase  Price as a result of the
calculations made in Sections 11(b) and (c), each Right outstanding  immediately
prior to the making of such adjustment  shall  thereafter  evidence the right to
purchase, at the adjusted Purchase Price, that number of one one-hundredths of a
Preferred  Share  (calculated  to the nearest one  one-millionth  of a Preferred
Share)  obtained by (i) multiplying  (x) the number of one  one-hundredths  of a
share  covered  by a  Right  immediately  prior  to this  adjustment  by (y) the
Purchase Price in effect  immediately  prior to such  adjustment of the Purchase
Price and (ii) dividing the product so obtained by the Purchase  Price in effect
immediately after such adjustment of the Purchase Price.

<PAGE>

         (i) The Company may elect on or after the date of any adjustment of the
Purchase  Price  to  adjust  the  number  of  Rights,  in  substitution  for any
adjustment in the number of one  one-hundredths of a Preferred Share purchasable
upon  the  exercise  of a  Right.  Each of the  Rights  outstanding  after  such
adjustment  of the number of Rights shall be  exercisable  for the number of one
one-hundredths   of  a  Preferred  Share  for  which  a  Right  was  exercisable
immediately  prior to such  adjustment.  Each Right held of record prior to such
adjustment  of  the  number  of  Rights  shall  become  that  number  of  Rights
(calculated to the nearest one ten-thousandth) obtained by dividing the Purchase
Price in effect  immediately  prior to adjustment  of the Purchase  Price by the
Purchase Price in effect immediately after adjustment of the Purchase Price. The
Company shall make a public announcement of its election to adjust the number of
Rights,  indicating  the record  date for the  adjustment,  and, if known at the
time, the amount of the adjustment to be made.  This record date may be the date
on which the Purchase Price is adjusted or any day thereafter, but, if the Right
Certificates have been issued,  shall be at least 10 days later than the date of
the public  announcement.  If Right  Certificates  have been  issued,  upon each
adjustment of the number of Rights  pursuant to this Section 11(i),  the Company
shall, as promptly as practicable,  cause to be distributed to holders of record
of Right Certificates on such record date Right Certificates evidencing, subject
to Section 14  hereof,  the  additional  Rights to which such  holders  shall be
entitled as a result of such adjustment, or, at the option of the Company, shall
cause  to  be  distributed  to  such  holders  of  record  in  substitution  and
replacement for the Right Certificates held by such holders prior to the date of
adjustment,  and upon surrender thereof,  if required by the Company,  new Right
Certificates  evidencing  all the Rights to which such holders shall be entitled
after such adjustment.  Right Certificates so to be distributed shall be issued,
executed  and  countersigned  in the  manner  provided  for  herein and shall be
registered  in the names of the holders of record of Right  Certificates  on the
record date specified in the public announcement.

         (j)  Irrespective  of any adjustment or change in the Purchase Price or
the number of one one-hundredths of a Preferred Share issuable upon the exercise
of the Rights,  the Right  Certificates  theretofore  and thereafter  issued may
continue to express the Purchase Price and the number of one one-hundredths of a
Preferred  Share which were expressed in the initial Right  Certificates  issued
hereunder.

         (k) Before  taking any action that would cause an  adjustment  reducing
the Purchase Price below one one-hundredth of the then par value, if any, of the
Preferred  Shares  issuable upon exercise of the Rights,  the Company shall take
any corporate  action which may, in the opinion of its counsel,  be necessary in
order  that  the  Company   may  validly  and  legally   issue  fully  paid  and
nonassessable Preferred Shares at such adjusted Purchase Price.

         (l) In any  case  in  which  this  Section  11  shall  require  that an
adjustment  in the  Purchase  Price be made  effective as of a record date for a
specified  event,  the Company may elect to defer until the  occurrence  of such
event the issuing to the holder of any Right exercised after such record date of
the Preferred  Shares and other  capital stock or securities of the Company,  if
any,  issuable upon such exercise over and above the Preferred  Shares and other
capital stock or securities of the Company,  if any, issuable upon such exercise
on the

<PAGE>

basis of the  Purchase  Price in  effect  prior  to such  adjustment;  provided,
however,  that the  Company  shall  deliver  to such  holder a due bill or other
appropriate instrument evidencing such holder's right to receive such additional
shares upon the occurrence of the event requiring such adjustment.

         (m) Anything in this Section 11 to the  contrary  notwithstanding,  the
Company  shall be entitled to make such  reductions  in the Purchase  Price,  in
addition to those adjustments  expressly  required by this Section 11, as and to
the extent that it in its sole  discretion  shall  determine  to be advisable in
order that any  consolidation or subdivision of the Preferred  Shares,  issuance
wholly for cash of any Preferred  Shares at less than the current  market price,
issuance wholly for cash of Preferred  Shares or securities which by their terms
are  convertible  into  or  exchangeable  for  Preferred  Shares,  dividends  on
Preferred Shares payable in Preferred  Shares or issuance of rights,  options or
warrants referred to hereinabove in Section 11(b), hereafter made by the Company
to holders of its Preferred Shares shall not be taxable to such stockholders.

         (n) In the event that at any time after the date of this  Agreement and
prior to the  Distribution  Date,  the  Company  shall  (i)  declare  or pay any
dividend  on the  Common  Shares  payable  in  Common  Shares  or (ii)  effect a
subdivision,   combination   or   consolidation   of  the   Common   Shares  (by
reclassification  or otherwise  than by payment of  dividends in Common  Shares)
into a greater or lesser number of Common Shares,  then in any such case (A) the
number of one  one-hundredths  of a Preferred Share purchasable after such event
upon proper exercise of each Right shall be determined by multiplying the number
of one  one-hundredths of a Preferred Share so purchasable  immediately prior to
such event by a fraction,  the numerator of which is the number of Common Shares
outstanding  immediately  before such event and the  denominator of which is the
number of Common Shares  outstanding  immediately after such event, and (B) each
Common  Share  outstanding  immediately  after such event shall have issued with
respect  to it that  number  of  Rights  which  each  Common  Share  outstanding
immediately  prior to such event had issued with respect to it. The  adjustments
provided for in this Section  11(n) shall be made  successively  whenever such a
dividend is declared or paid or such a subdivision, combination or consolidation
is effected.

         Section 12. Certificate of Adjusted Purchase Price or Number of Shares.
Whenever  an  adjustment  is made as  provided  in Section 11 or 13 hereof,  the
Company shall promptly (a) prepare a certificate  setting forth such adjustment,
and a brief statement of the facts accounting for such adjustment, (b) file with
the  Rights  Agent and with each  transfer  agent for the  Common  Shares or the
Preferred Shares a copy of such certificate and (c) mail a brief summary thereof
to each holder of a Right Certificate in accordance with Section 25 hereof.

         Section  13.  Consolidation,  Merger or Sale or  Transfer  of Assets or
Earning Power. In the event, directly or indirectly,  at any time after a Person
has become an Acquiring Person, (a) the Company shall consolidate with, or merge
with and into,  any other  Person,  (b) any Person  shall  consolidate  with the
Company,  or  merge  with  and into the  Company  and the  Company  shall be the
continuing or surviving  corporation of such merger and, in

<PAGE>

connection  with such merger,  all or part of the Common Shares shall be changed
into or  exchanged  for stock or other  securities  of any other  Person (or the
Company)  or cash  or any  other  property,  or (c) the  Company  shall  sell or
otherwise  transfer (or one or more of its Subsidiaries  shall sell or otherwise
transfer), in one or more transactions,  assets or earning power aggregating 50%
or more of the  assets or  earning  power of the  Company  and its  Subsidiaries
(taken as a whole) to any other  Person other than the Company or one or more of
its  wholly-owned  Subsidiaries,  then, and in each such case,  proper provision
shall be made so that (i) each holder of a Right  (except as otherwise  provided
herein) shall thereafter have the right to receive, upon the exercise thereof at
a price equal to the then current Purchase Price multiplied by the number of one
one-hundredths  of a Preferred Share for which a Right is then  exercisable,  in
accordance  with the terms of this  Agreement  and in lieu of Preferred  Shares,
such  number of Common  Shares of such other  Person  (including  the Company as
successor  thereto or as the  surviving  corporation)  as shall equal the result
obtained by (A) multiplying the then current Purchase Price by the number of one
one-hundredths  of a Preferred  Share for which a Right is then  exercisable and
dividing  that  product by (B) 50% of the then current per share market price of
the Common  Shares of such other Person  (determined  pursuant to Section  11(d)
hereof)  on the date of  consummation  of such  consolidation,  merger,  sale or
transfer;  (ii) the issuer of such Common Shares shall thereafter be liable for,
and shall assume, by virtue of such consolidation, merger, sale or transfer, all
the obligations and duties of the Company pursuant to this Agreement;  (iii) the
term "Company" shall thereafter be deemed to refer to such issuer; and (iv) such
issuer shall take such steps (including,  but not limited to, the reservation of
a sufficient number of its Common Shares in accordance with Section 9 hereof) in
connection  with  such  consummation  as may be  necessary  to  assure  that the
provisions  hereof shall  thereafter be applicable,  as nearly as reasonably may
be, in relation to the Common Shares thereafter deliverable upon the exercise of
the Rights.  The Company shall not  consummate any such  consolidation,  merger,
sale or transfer  unless  prior  thereto the Company and such issuer  shall have
executed  and  delivered  to  the  Rights  Agent  a  supplemental  agreement  so
providing. The Company shall not enter into any transaction of the kind referred
to in this Section 13 if at the time of such  transaction  there are any rights,
warrants,   instruments   or  securities   outstanding   or  any  agreements  or
arrangements  which, as a result of the consummation of such transaction,  would
eliminate or substantially  diminish the benefits intended to be afforded by the
Rights.  The provisions of this Section 13 shall  similarly  apply to successive
mergers or consolidations or sales or other transfers.

         Section 14.  Fractional Rights and Fractional  Shares.  (a) The Company
shall not be  required  to issue  fractions  of Rights  or to  distribute  Right
Certificates  which  evidence  fractional  Rights.  In lieu  of such  fractional
Rights,  there shall be paid to the registered holders of the Right Certificates
with regard to which such  fractional  Rights would  otherwise  be issuable,  an
amount in cash equal to the same fraction of the current market value of a whole
Right.  For the purposes of this Section  14(a),  the current  market value of a
whole  Right  shall be the  closing  price of the  Rights  for the  Trading  Day
immediately  prior to the date on which such  fractional  Rights would have been
otherwise issuable.  The closing price for any day shall be the last sale price,
regular  way,  or, in case no such sale takes place on such day,  the average of
the closing bid and asked prices, regular way, in either case as reported in the
principal  consolidated  transaction reporting system with respect to securities
listed or

<PAGE>

admitted  to trading on the New York  Stock  Exchange  or, if the Rights are not
listed or admitted to trading on the New York Stock Exchange, as reported in the
principal  consolidated  transaction reporting system with respect to securities
listed on the  principal  national  securities  exchange on which the Rights are
listed or  admitted  to trading  or, if the Rights are not listed or admitted to
trading on any national securities exchange, the last quoted price or, if not so
quoted, the average of the high bid and low asked prices in the over-the-counter
market,  as  reported  by NASDAQ or such other  system then in use or, if on any
such date the Rights are not quoted by any such organization, the average of the
closing bid and asked prices as furnished by a professional  market maker making
a market in the Rights selected by the Board of Directors of the Company.  If on
any such date no such market  maker is making a market in the  Rights,  the fair
value of the  Rights on such date as  determined  in good  faith by the Board of
Directors of the Company shall be used.

         (b) The Company  shall not be required to issue  fractions of Preferred
Shares (other than fractions which are integral  multiples of one  one-hundredth
of a Preferred Share) upon exercise of the Rights or to distribute  certificates
which  evidence  fractional  Preferred  Shares (other than  fractions  which are
integral  multiples of one  one-hundredth  of a Preferred  Share).  Fractions of
Preferred Shares in integral multiples of one one-hundredth of a Preferred Share
may, at the  election of the  Company,  be  evidenced  by  depositary  receipts,
pursuant to an  appropriate  agreement  between  the  Company  and a  depositary
selected by it; provided,  that such agreement shall provide that the holders of
such depositary  receipts shall have all the rights,  privileges and preferences
to which  they  are  entitled  as  beneficial  owners  of the  Preferred  Shares
represented by such depositary receipts.  In lieu of fractional Preferred Shares
that are not integral  multiples of one  one-hundredth of a Preferred Share, the
Company shall pay to the registered  holders of Right  Certificates  at the time
such Rights are exercised as herein provided an amount in cash equal to the same
fraction of the current market value of one Preferred Share. For the purposes of
this Section 14(b),  the current market value of a Preferred  Share shall be the
closing  price of a  Preferred  Share  (as  determined  pursuant  to the  second
sentence of Section  11(d)(i)  hereof) for the Trading Day immediately  prior to
the date of such exercise.

         (c) The  holder of a Right by the  acceptance  of the  Right  expressly
waives his right to receive any fractional  Rights or any fractional shares upon
exercise of a Right (except as provided above).

         Section 15.  Rights of Action.  All rights of action in respect of this
Agreement,  excepting  the  rights of action  given to the  Rights  Agent  under
Section 18 hereof, are vested in the respective  registered holders of the Right
Certificates (and, prior to the Distribution Date, the registered holders of the
Common Shares); and any registered holder of any Right Certificate (or, prior to
the Distribution Date, of the Common Shares),  without the consent of the Rights
Agent  or of the  holder  of any  other  Right  Certificate  (or,  prior  to the
Distribution Date, of the Common Shares), may, in his own behalf and for his own
benefit,  enforce, and may institute and maintain any suit, action or proceeding
against  the Company to enforce,  or  otherwise  act in respect of, his right to
exercise the Rights  evidenced by such Right  Certificate in the manner provided
in such Right Certificate and in this Agreement.

<PAGE>

Without  limiting  the  foregoing  or any  remedies  available to the holders of
Rights,  it is  specifically  acknowledged  that the holders of Rights would not
have an  adequate  remedy at law for any  breach of this  Agreement  and will be
entitled to specific performance of the obligations under, and injunctive relief
against actual or threatened violations of the obligations of any Person subject
to, this Agreement.

         Section 16.  Agreement of Right  Holders.  Every holder of a Right,  by
accepting  the same,  consents  and agrees with the Company and the Rights Agent
and with every other holder of a Right that:

         (a) prior to the  Distribution  Date,  the Rights will be  transferable
only in connection with the transfer of the Common Shares;

         (b)  after  the   Distribution   Date,  the  Right   Certificates   are
transferable  only on the registry  books of the Rights Agent if  surrendered at
the principal  office of the Rights Agent,  duly  endorsed or  accompanied  by a
proper instrument of transfer; and

         (c) the Company  and the Rights  Agent may deem and treat the person in
whose  name the Right  Certificate  (or,  prior to the  Distribution  Date,  the
associated  Common  Shares  certificate)  is  registered  as the absolute  owner
thereof and of the Rights evidenced  thereby  (notwithstanding  any notations of
ownership or writing on the Right  Certificates or the associated  Common Shares
certificate  made by anyone other than the Company or the Rights  Agent) for all
purposes  whatsoever,  and neither  the  Company  nor the Rights  Agent shall be
affected by any notice to the contrary.

         Section  17.  Right  Certificate  Holder Not Deemed a  Stockholder.  No
holder,  as such, of any Right  Certificate  shall be entitled to vote,  receive
dividends or be deemed for any purpose the holder of the Preferred Shares or any
other  securities  of the  Company  which  may at any  time be  issuable  on the
exercise of the Rights represented  thereby, nor shall anything contained herein
or in any Right  Certificate be construed to confer upon the holder of any Right
Certificate,  as such,  any of the rights of a stockholder of the Company or any
right to vote for the  election of  directors  or upon any matter  submitted  to
stockholders  at any  meeting  thereof,  or to give or  withhold  consent to any
corporate  action,  or to receive notice of meetings or other actions  affecting
stockholders  (except as provided in Section 25 hereof), or to receive dividends
or subscription  rights,  or otherwise,  until the Right or Rights  evidenced by
such  Right  Certificate  shall  have  been  exercised  in  accordance  with the
provisions hereof.

         Section 18.  Concerning the Rights Agent.  The Company agrees to pay to
the  Rights  Agent  reasonable  compensation  for all  services  rendered  by it
hereunder and, from time to time, on demand of the Rights Agent,  its reasonable
expenses and counsel fees and other disbursements incurred in the administration
and execution of this  Agreement and the exercise and  performance of its duties
hereunder.  The Company  also agrees to  indemnify  the Rights Agent for, and to
hold it harmless  against,  any loss,  liability,  or expense,  incurred without
negligence, bad faith or willful misconduct on the part of the Rights Agent, for
anything done or omitted by the Rights Agent in connection  with the  acceptance
and 

<PAGE>

administration of this Agreement,  including the costs and expenses of defending
against any claim of liability in the premises.

         The Rights Agent shall be protected  and shall incur no liability  for,
or in respect of any action taken, suffered or omitted by it in connection with,
its  administration  of this Agreement in reliance upon any Right Certificate or
certificate for the Preferred Shares or Common Shares or for other securities of
the  Company,   instrument  of  assignment  or  transfer,   power  of  attorney,
endorsement,   affidavit,  letter,  notice,  direction,   consent,  certificate,
statement,  or other  paper or  document  believed by it to be genuine and to be
signed, executed and, where necessary,  verified or acknowledged,  by the proper
person or  persons,  or  otherwise  upon the  advice of  counsel as set forth in
Section 20 hereof.

         Section 19. Merger or  Consolidation or Change of Name of Rights Agent.
Any corporation into which the Rights Agent or any successor Rights Agent may be
merged or with which it may be consolidated,  or any corporation  resulting from
any merger or  consolidation  to which the Rights Agent or any successor  Rights
Agent shall be a party, or any  corporation  succeeding to the stock transfer or
corporate trust powers of the Rights Agent or any successor Rights Agent,  shall
be the successor to the Rights Agent under this Agreement  without the execution
or  filing  of any paper or any  further  act on the part of any of the  parties
hereto;  provided,  that such corporation would be eligible for appointment as a
successor Rights Agent under the provisions of Section 21 hereof. In case at the
time such  successor  Rights Agent shall  succeed to the agency  created by this
Agreement,  any of the Right  Certificates shall have been countersigned but not
delivered, any such successor Rights Agent may adopt the countersignature of the
predecessor  Rights Agent and deliver such Right  Certificates so countersigned;
and in case at that  time any of the  Right  Certificates  shall  not have  been
countersigned,   any  successor   Rights  Agent  may   countersign   such  Right
Certificates  either in the name of the predecessor  Rights Agent or in the name
of the  successor  Rights Agent;  and in all such cases such Right  Certificates
shall  have  the full  force  provided  in the  Right  Certificates  and in this
Agreement.

         In case at any time the name of the Rights  Agent  shall be changed and
at such time any of the Right Certificates shall have been countersigned but not
delivered,  the Rights Agent may adopt the countersignature under its prior name
and deliver Right Certificates so countersigned; and in case at that time any of
the Right Certificates shall not have been  countersigned,  the Rights Agent may
countersign such Right  Certificates  either in its prior name or in its changed
name;  and in all such cases such Right  Certificates  shall have the full force
provided in the Right Certificates and in this Agreement.

         Section 20. Duties of Rights  Agent.  The Rights Agent  undertakes  the
duties and  obligations  imposed by this Agreement upon the following  terms and
conditions,  by all of which the Company and the holders of Right  Certificates,
by their acceptance thereof, shall be bound:

         (a) The Rights Agent may consult  with legal  counsel (who may be legal
counsel  for the  Company),  and the opinion of such  counsel  shall be full and
complete

<PAGE>

authorization  and  protection  to the Rights  Agent as to any  action  taken or
omitted by it in good faith and in accordance with such opinion.

         (b) Whenever in the  performance of its duties under this Agreement the
Rights Agent shall deem it  necessary  or  desirable  that any fact or matter be
proved or  established  by the Company  prior to taking or suffering  any action
hereunder,  such fact or matter  (unless  other  evidence in respect  thereof be
herein  specifically  prescribed)  may be deemed to be  conclusively  proved and
established by a certificate signed by any one of the Chairman of the Board, the
Chief Executive Officer, the President, any Vice President, the Treasurer or the
Secretary of the Company and delivered to the Rights Agent; and such certificate
shall be full authorization to the Rights Agent for any action taken or suffered
in good faith by it under the provisions of this Agreement in reliance upon such
certificate.

         (c) The Rights  Agent shall be liable  hereunder to the Company and any
other Person only for its own negligence, bad faith or willful misconduct.

         (d) The Rights Agent shall not be liable for or by reason of any of the
statements  of fact or  recitals  contained  in this  Agreement  or in the Right
Certificates (except its countersignature  thereof) or be required to verify the
same, but all such  statements and recitals are and shall be deemed to have been
made by the Company only.

         (e) The Rights Agent shall not be under any  responsibility  in respect
of the validity of this  Agreement or the execution and delivery  hereof (except
the due  execution  hereof by the Rights Agent) or in respect of the validity or
execution of any Right Certificate (except its  countersignature  thereof);  nor
shall it be  responsible  for any  breach  by the  Company  of any  covenant  or
condition contained in this Agreement or in any Right Certificate;  nor shall it
be responsible for any change in the exercisability of the Rights (including the
Rights becoming void pursuant to Section  11(a)(ii) hereof) or any adjustment in
the terms of the  Rights  (including  the  manner,  method  or  amount  thereof)
provided  for in  Section  3,  11,  13,  23 or 24,  or the  ascertaining  of the
existence of facts that would require any such change or adjustment (except with
respect to the exercise of Rights evidenced by Right  Certificates  after actual
notice  that such change or  adjustment  is  required);  nor shall it by any act
hereunder  be  deemed  to  make  any   representation  or  warranty  as  to  the
authorization  or reservation of any Preferred  Shares to be issued  pursuant to
this Agreement or any Right  Certificate  or as to whether any Preferred  Shares
will,  when  issued,   be  validly   authorized  and  issued,   fully  paid  and
nonassessable.

         (f) The Company agrees that it will perform,  execute,  acknowledge and
deliver or cause to be performed, executed,  acknowledged and delivered all such
further and other acts, instruments and assurances as may reasonably be required
by the Rights Agent for the carrying  out or  performing  by the Rights Agent of
the provisions of this Agreement.

         (g) The  Rights  Agent is  hereby  authorized  and  directed  to accept
instructions  with respect to the  performance of its duties  hereunder from any
one of the  Chairman  of the  Board,  the Vice  Chairman,  the  Chief  Executive
Officer,  the President,  any Vice President,  the

<PAGE>

Secretary or the  Treasurer of the  Company,  and to apply to such  officers for
advice or instructions in connection with its duties, and it shall not be liable
for any  action  taken  or  suffered  by it in good  faith  in  accordance  with
instructions  of any such officer or for any delay in acting  while  waiting for
those instructions.

         (h) The Rights Agent and any stockholder, director, officer or employee
of the  Rights  Agent  may  buy,  sell  or deal in any of the  Rights  or  other
securities of the Company or become pecuniarily interested in any transaction in
which the  Company  may be  interested,  or  contract  with or lend money to the
Company or otherwise  act as fully and freely as though it were not Rights Agent
under this Agreement. Nothing herein shall preclude the Rights Agent from acting
in any other capacity for the Company or for any other legal entity.

         (i) The Rights  Agent may  execute  and  exercise  any of the rights or
powers hereby vested in it or perform any duty hereunder  either itself or by or
through its attorneys or agents, and the Rights Agent shall not be answerable or
accountable for any act, default, neglect or misconduct of any such attorneys or
agents or for any loss to the  Company  resulting  from any such  act,  default,
neglect or misconduct,  provided  reasonable care was exercised in the selection
and continued employment thereof.

         Section 21. Change of Rights  Agent.  The Rights Agent or any successor
Rights Agent may resign and be discharged  from its duties under this  Agreement
upon 30 days' notice in writing mailed to the Company and to each transfer agent
of the Common Shares or Preferred Shares by registered or certified mail, and to
the  holders of the Right  Certificates  by  first-class  mail.  The Company may
remove the Rights  Agent or any  successor  Rights Agent upon 30 days' notice in
writing,  mailed to the Rights Agent or successor  Rights Agent, as the case may
be, and to each  transfer  agent of the  Common  Shares or  Preferred  Shares by
registered or certified  mail, and to the holders of the Right  Certificates  by
first-class  mail.  If the  Rights  Agent  shall  resign or be  removed or shall
otherwise become  incapable of acting,  the Company shall appoint a successor to
the Rights Agent.  If the Company shall fail to make such  appointment  within a
period  of 30 days  after  giving  notice of such  removal  or after it has been
notified  in writing of such  resignation  or  incapacity  by the  resigning  or
incapacitated  Rights Agent or by the holder of a Right  Certificate (who shall,
with such notice,  submit his Right  Certificate for inspection by the Company),
then the registered  holder of any Right  Certificate  may apply to any court of
competent  jurisdiction for the appointment of a new Rights Agent. Any successor
Rights Agent,  whether  appointed by the Company or by such a court,  shall be a
corporation  organized and doing business under the laws of the United States or
of the State of Illinois (or of any other state of the United  States so long as
such  corporation  is authorized to do business as a banking  institution in the
State of Illinois, in good standing,  having an office in the State of Illinois,
which  is  authorized  under  such  laws to  exercise  corporate  trust or stock
transfer powers and is subject to supervision or examination by federal or state
authority  and  which  has at the  time of its  appointment  as  Rights  Agent a
combined  capital and surplus of at least $50 million.  After  appointment,  the
successor Rights Agent shall be vested with the same powers,  rights, duties and
responsibilities  as if it had been  originally  named as Rights  Agent  without
further act or deed; but the predecessor Rights Agent shall deliver and transfer
to the successor Rights Agent any property at the time held by

<PAGE>

it hereunder, and execute and deliver any further assurance,  conveyance, act or
deed  necessary for the purpose.  Not later than the effective  date of any such
appointment   the  Company  shall  file  notice  thereof  in  writing  with  the
predecessor  Rights  Agent  and each  transfer  agent of the  Common  Shares  or
Preferred Shares, and mail a notice thereof in writing to the registered holders
of the Right  Certificates.  Failure  to give any  notice  provided  for in this
Section 21,  however,  or any defect  therein,  shall not affect the legality or
validity of the resignation or removal of the Rights Agent or the appointment of
the successor Rights Agent, as the case may be.

         Section 22. Issuance of New Right Certificates.  Notwithstanding any of
the provisions of this  Agreement or of the Rights to the contrary,  the Company
may, at its option, issue new Right Certificates  evidencing Rights in such form
as may be approved by its Board of Directors to reflect any adjustment or change
in the  Purchase  Price  and the  number  or kind or  class of  shares  or other
securities  or  property  purchasable  under  the  Right  Certificates  made  in
accordance with the provisions of this Agreement.

         Section 23. Redemption.  (a) The Board of Directors of the Company may,
at its option, at any time prior to such time as any Person becomes an Acquiring
Person,  redeem  all but not  less  than all the then  outstanding  Rights  at a
redemption price of $.01 per Right,  appropriately adjusted to reflect any stock
split,  stock dividend or similar  transaction  occurring  after the date hereof
(such redemption price being hereinafter referred to as the "Redemption Price").
The  redemption of the Rights by the Board of Directors may be made effective at
such time,  on such basis and with such  conditions as the Board of Directors in
its sole discretion may establish.

         (b)  Immediately  upon the  action  of the  Board of  Directors  of the
Company  ordering the redemption of the Rights pursuant to paragraph (a) of this
Section 23, and without any further action and without any notice,  the right to
exercise the Rights will terminate and the only right  thereafter of the holders
of Rights shall be to receive the Redemption  Price.  The Company shall promptly
give public notice of any such redemption;  provided,  however, that the failure
to give, or any defect in, any such notice shall not affect the validity of such
redemption.  Within 10 days after such action of the Board of Directors ordering
the  redemption of the Rights,  the Company shall mail a notice of redemption to
all the holders of the then  outstanding  Rights at their last addresses as they
appear upon the registry books of the Rights Agent or, prior to the Distribution
Date, on the registry  books of the transfer  agent for the Common  Shares.  Any
notice  which is mailed in the manner  herein  provided  shall be deemed  given,
whether or not the holder  receives the notice.  Each such notice of  redemption
will state the method by which the payment of the Redemption Price will be made.
Neither the Company nor any of its Affiliates or Associates may redeem,  acquire
or  purchase  for value any  Rights at any time in any  manner  other  than that
specifically  set forth in this  Section 23 or in  Section 24 hereof,  and other
than in connection with the purchase of Common Shares prior to the  Distribution
Date.

         Section 24. Exchange. (a) The Board of Directors of the Company may, at
its option, at any time after any Person becomes an Acquiring  Person,  exchange
all or part of the 

<PAGE>

then  outstanding  and  exercisable  Rights (which shall not include Rights that
have become void  pursuant to the  provisions of Section  11(a)(ii)  hereof) for
Common Shares at an exchange ratio of one Common Share per Right,  appropriately
adjusted  to reflect any stock  split,  stock  dividend  or similar  transaction
occurring after the date hereof (such exchange ratio being hereinafter  referred
to as the  "Exchange  Ratio").  Notwithstanding  the  foregoing,  the  Board  of
Directors  shall not be empowered to effect such  exchange at any time after any
Person  (other than the Company,  any  Subsidiary  of the Company,  any employee
benefit plan of the Company or any such Subsidiary, or any entity holding Common
Shares  for or  pursuant  to the  terms of any  such  plan),  together  with all
Affiliates and Associates of such Person, becomes the Beneficial Owner of 50% or
more of the Common Shares then outstanding.

         (b)  Immediately  upon the  action  of the  Board of  Directors  of the
Company  ordering the exchange of any Rights  pursuant to paragraph  (a) of this
Section 24 and without any further  action and without any notice,  the right to
exercise such Rights shall  terminate and the only right  thereafter of a holder
of such Rights  shall be to receive  that number of Common  Shares  equal to the
number of such Rights held by such holder  multiplied by the Exchange Ratio. The
Company  shall  promptly  give  public  notice of any such  exchange;  provided,
however,  that the  failure to give,  or any defect in,  such  notice  shall not
affect the validity of such exchange.  The Company  promptly shall mail a notice
of any  such  exchange  to all of the  holders  of such  Rights  at  their  last
addresses as they appear upon the registry books of the Rights Agent. Any notice
which is mailed in the manner herein provided shall be deemed given,  whether or
not the holder receives the notice.  Each such notice of exchange will state the
method by which the  exchange  of the Common  Shares for Rights will be effected
and, in the event of any partial  exchange,  the number of Rights  which will be
exchanged.  Any partial  exchange shall be effected pro rata based on the number
of Rights (other than Rights which have become void  pursuant to the  provisions
of Section 11(a)(ii) hereof) held by each holder of Rights.

         (c) In the event  that  there  shall not be  sufficient  Common  Shares
issued but not  outstanding or authorized but unissued to permit any exchange of
Rights as  contemplated  in  accordance  with this Section 24, the Company shall
take all such action as may be necessary to authorize  additional  Common Shares
for issuance upon exchange of the Rights. In the event the Company shall,  after
good faith  effort,  be unable to take all such  action as may be  necessary  to
authorize such additional Common Shares, the Company shall substitute,  for each
Common Share that would otherwise be issuable upon exchange of a Right, a number
of Preferred  Shares or fraction  thereof such that the current per share market
price of one Preferred  Share  multiplied by such number or fraction is equal to
the  current  per  share  market  price  of one  Common  Share as of the date of
issuance of such Preferred Shares or fraction thereof.

         (d) The  Company  shall not be required  to issue  fractions  of Common
Shares or to distribute certificates which evidence fractional Common Shares. In
lieu of such fractional  Common Shares,  the Company shall pay to the registered
holders of the Right  Certificates  with regard to which such fractional  Common
Shares would  otherwise be issuable an amount in cash equal to the same fraction
of the current  market value of a whole Common 

<PAGE>

Share.  For the purposes of this  paragraph  (d), the current  market value of a
whole Common Share shall be the closing  price of a Common Share (as  determined
pursuant to the second sentence of Section  11(d)(i) hereof) for the Trading Day
immediately prior to the date of exchange pursuant to this Section 24.

         Section 25.  Notice of Certain  Events.  (a) In case the Company  shall
propose (i) to pay any dividend  payable in stock of any class to the holders of
its  Preferred  Shares or to make any other  distribution  to the holders of its
Preferred Shares (other than a regular  quarterly cash dividend),  (ii) to offer
to the holders of its Preferred Shares rights or warrants to subscribe for or to
purchase any additional  Preferred Shares or shares of stock of any class or any
other securities, rights or options, (iii) to effect any reclassification of its
Preferred Shares (other than a  reclassification  involving only the subdivision
of outstanding  Preferred  Shares),  (iv) to effect any  consolidation or merger
into or with, or to effect any sale or other  transfer (or to permit one or more
of its  Subsidiaries  to  effect  any  sale or other  transfer),  in one or more
transactions,  of 50% or more of the assets or earning  power of the Company and
its  Subsidiaries  (taken as a whole)  to, any other  Person,  (v) to effect the
liquidation, dissolution or winding up of the Company, or (vi) to declare or pay
any  dividend  on the  Common  Shares  payable  in Common  Shares or to effect a
subdivision,   combination   or   consolidation   of  the   Common   Shares  (by
reclassification  or otherwise  than by payment of dividends in Common  Shares),
then,  in each such  case,  the  Company  shall  give to each  holder of a Right
Certificate,  in  accordance  with Section 26 hereof,  a notice of such proposed
action,  which  shall  specify  the record  date for the  purposes of such stock
dividend,  or  distribution  of rights or  warrants,  or the date on which  such
reclassification,    consolidation,   merger,   sale,   transfer,   liquidation,
dissolution,  or  winding  up is to take  place  and the  date of  participation
therein by the holders of the Common Shares and/or Preferred Shares, if any such
date is to be fixed, and such notice shall be so given in the case of any action
covered by clause  (i) or (ii)  above at least 10 days prior to the record  date
for determining holders of the Preferred Shares for purposes of such action, and
in the case of any such other action,  at least 10 days prior to the date of the
taking of such  proposed  action  or the date of  participation  therein  by the
holders of the Common Shares and/or  Preferred  Shares,  whichever  shall be the
earlier.

         (b) In case the event  set  forth in  Section  11(a)(ii)  hereof  shall
occur,  then the Company shall as soon as  practicable  thereafter  give to each
holder of a Right Certificate, in accordance with Section 26 hereof, a notice of
the  occurrence  of such event,  which notice shall  describe such event and the
consequences of such event to holders of Rights under Section 11(a)(ii) hereof.

         Section 26. Notices. Notices or demands authorized by this Agreement to
be given or made by the Rights  Agent or by the holder of any Right  Certificate
to or on the Company shall be sufficiently  given or made if sent by first-class
mail, postage prepaid, addressed (until another address is filed in writing with
the Rights Agent) as follows:

<PAGE>

                           Covance Inc.
                           210 Carnegie Center
                           Princeton, New Jersey 08540
                           Attention:  Corporate Secretary


Subject to the provisions of Section 21 hereof,  any notice or demand authorized
by this  Agreement  to be given or made by the  Company  or by the holder of any
Right Certificate to or on the Rights Agent shall be sufficiently  given or made
if sent by first-class mail,  postage prepaid,  addressed (until another address
is filed in writing with the Company) as follows:


                           Harris Trust and Savings Bank
                           311 West Monroe, 11th Floor
                           P.O. Box 755
                           Chicago, Illinois  60690


Notices  or  demands  authorized  by this  Agreement  to be given or made by the
Company or the  Rights  Agent to the  holder of any Right  Certificate  shall be
sufficiently  given  or  made  if sent by  first-class  mail,  postage  prepaid,
addressed  to such holder at the address of such holder as shown on the registry
books of the Company.

         Section 27.  Supplements and  Amendments.  The Company may from time to
time  supplement or amend this Agreement  without the approval of any holders of
Right Certificates in order to cure any ambiguity,  to correct or supplement any
provision contained herein which may be defective or inconsistent with any other
provisions  herein,  or to make any other  provisions with respect to the Rights
which the  Company may deem  necessary  or  desirable,  any such  supplement  or
amendment  to be  evidenced  by a writing  signed by the  Company and the Rights
Agent; provided, however, that from and after such time as any Person becomes an
Acquiring Person,  this Agreement shall not be amended in any manner which would
adversely affect the interests of the holders of Rights.

         Section  28.  Successors.  All the  covenants  and  provisions  of this
Agreement  by or for the benefit of the  Company or the Rights  Agent shall bind
and inure to the benefit of their respective successors and assigns hereunder.

         Section 29. Benefits of this Agreement. Nothing in this Agreement shall
be construed to give to any person or  corporation  other than the Company,  the
Rights Agent and the registered holders of the Right Certificates (and, prior to
the Distribution  Date, the Common Shares) any legal or equitable right,  remedy
or claim  under this  Agreement;  but this  Agreement  shall be for the sole and
exclusive benefit of the Company, the Rights Agent and the registered holders of
the Right Certificates (and, prior to the Distribution Date, the Common Shares).

<PAGE>

         Section  30.  Severability.   If  any  term,  provision,   covenant  or
restriction  of this Agreement is held by a court of competent  jurisdiction  or
other  authority  to be invalid,  void or  unenforceable,  the  remainder of the
terms, provisions,  covenants and restrictions of this Agreement shall remain in
full force and effect and shall in no way be affected, impaired or invalidated.

         Section 31.  Governing Law. This  Agreement and each Right  Certificate
issued  hereunder  shall be deemed to be a  contract  made under the laws of the
State of Delaware  and for all  purposes  shall be governed by and  construed in
accordance  with the laws of such State  applicable  to contracts to be made and
performed entirely within such State.

         Section 32. Counterparts.  This Agreement may be executed in any number
of counterparts and each of such  counterparts  shall for all purposes be deemed
to be an original,  and all such counterparts shall together  constitute but one
and the same instrument.

         Section 33. Descriptive  Headings.  Descriptive headings of the several
Sections of this  Agreement  are  inserted  for  convenience  only and shall not
control or affect the meaning or construction of any of the provisions hereof.

         IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
duly executed and attested, all as of the day and year first above written.



Attest:                                  COVANCE INC.


By:______________________________        By______________________________
   Title:                                   Title:



Attest:                                  HARRIS TRUST AND SAVINGS BANK


By:______________________________        By:______________________________
   Title:                                   Title:

<PAGE>

                                                                       Exhibit A

Form of Right Certificate


Certificate No. R-                  Rights



         NOT  EXERCISABLE  AFTER  DECEMBER 31, 2006 OR EARLIER IF
         REDEMPTION  OR EXCHANGE  OCCURS.  THE RIGHTS ARE SUBJECT
         TO REDEMPTION  AT $.01 PER  RIGHT AND TO EXCHANGE ON THE
         TERMS SET FORTH IN THE RIGHTS AGREEMENT.


                                Right Certificate

                                  COVANCE INC.


         This certifies that          , or registered assigns, is the registered
owner of the number of Rights set forth above,  each of which entitles the owner
thereof,  subject  to  the  terms,  provisions  and  conditions  of  the  Rights
Agreement,  dated as of December  31,  1996 (the  "Rights  Agreement"),  between
Covance  Inc.,  a Delaware  corporation  (the  "Company"),  and Harris Trust and
Savings  Bank (the  "Rights  Agent"),  to purchase  from the Company at any time
after the  Distribution  Date (as such term is defined in the Rights  Agreement)
and prior to 5:00 P.M.,  New York time,  on December  31, 2006 at the  principal
office of the Rights  Agent,  or at the office of its successor as Rights Agent,
one  one-hundredth  of a fully  paid  non-assessable  share  of  Series A Junior
Participating  Preferred  Stock,  par  value  $1.00 per  share  (the  "Preferred
Shares"), of the Company, at a purchase price of $100 per one one-hundredth of a
Preferred Share (the "Purchase Price"),  upon presentation and surrender of this
Right  Certificate  with the Form of  Election to Purchase  duly  executed.  The
number of Rights  evidenced  by this  Right  Certificate  (and the number of one
one-hundredths of a Preferred Share which may be purchased upon exercise hereof)
set forth  above,  and the Purchase  Price set forth  above,  are the number and
Purchase  Price as of  December  31,  1996,  based on the  Preferred  Shares  as
constituted  at such date.  As provided in the Rights  Agreement,  the  Purchase
Price and the number of one  one-hundredths  of a  Preferred  Share which may be
purchased  upon the exercise of the Rights  evidenced by this Right  Certificate
are subject to modification and adjustment upon the happening of certain events.

         This Right  Certificate is subject to all of the terms,  provisions and
conditions of the Rights Agreement,  which terms,  provisions and conditions are
hereby  incorporated  herein by  reference  and made a part  hereof and to which
Rights Agreement  reference is hereby made for a full description of the rights,
limitations  of rights,  obligations,  duties and  immunities  hereunder  of the
Rights Agent, the Company and the holders of the Right  Certificates.  Copies of
the  Rights  Agreement  are on file at the  principal  executive  offices of the
Company and the above-mentioned offices of the Rights Agent.


<PAGE>

         This Right Certificate, with or without other Right Certificates,  upon
surrender at the  principal  office of the Rights  Agent,  may be exchanged  for
another  Right  Certificate  or  Right  Certificates  of  like  tenor  and  date
evidencing  Rights  entitling the holder to purchase a like aggregate  number of
Preferred  Shares as the  Rights  evidenced  by the Right  Certificate  or Right
Certificates  surrendered  shall have entitled such holder to purchase.  If this
Right  Certificate  shall be exercised in part,  the holder shall be entitled to
receive upon surrender  hereof another Right  Certificate or Right  Certificates
for the number of whole Rights not exercised.

         Subject to the provisions of the Rights Agreement, the Rights evidenced
by this  Certificate (i) may be redeemed by the Company at a redemption price of
$.01 per Right or (ii) may be exchanged in whole or in part for Preferred Shares
or shares of the Company's Common Stock, no par value.

         No fractional  Preferred Shares will be issued upon the exercise of any
Right or Rights  evidenced  hereby  (other  than  fractions  which are  integral
multiples of one one-hundredth of a Preferred Share,  which may, at the election
of the Company, be evidenced by depositary receipts), but in lieu thereof a cash
payment will be made, as provided in the Rights Agreement.

         No  holder  of this  Right  Certificate  shall be  entitled  to vote or
receive  dividends  or be deemed for any  purpose  the  holder of the  Preferred
Shares  or of any  other  securities  of the  Company  which  may at any time be
issuable on the  exercise  hereof,  nor shall  anything  contained in the Rights
Agreement or herein be construed to confer upon the holder hereof,  as such, any
of the  rights  of a  stockholder  of the  Company  or any right to vote for the
election  of  directors  or upon any matter  submitted  to  stockholders  at any
meeting thereof,  or to give or withhold consent to any corporate  action, or to
receive notice of meetings or other actions  affecting  stockholders  (except as
provided  in the Rights  Agreement),  or to receive  dividends  or  subscription
rights,  or  otherwise,  until  the  Right or  Rights  evidenced  by this  Right
Certificate shall have been exercised as provided in the Rights Agreement.

         This Right Certificate shall not be valid or obligatory for any purpose
until it shall have been countersigned by the Rights Agent.

         WITNESS the facsimile  signature of the proper  officers of the Company
and its corporate seal. Dated as of .

ATTEST:                                    COVANCE INC.


   ______________________________        By ______________________________
   Name:                                    Name:
   Title:                                   Title:

                                      A-6

<PAGE>

Countersigned:


HARRIS TRUST AND SAVINGS BANK



By ______________________________    
   Name:
   Title:                            

                                       A-6

<PAGE>

                    Form of Reverse Side of Right Certificate


                               FORM OF ASSIGNMENT


(To be executed by the registered holder if such
holder desires to transfer the Right Certificate.)


                  FOR VALUE RECEIVED                   hereby sells, assigns and
transfers unto
(Please print name and address of transferee)

this Right Certificate, together with all right, title and interest therein, and
does hereby irrevocably  constitute and appoint Attorney, to transfer the within
Right Certificate on the books of the within-named  Company,  with full power of
substitution.


Dated: ________________________

                                       Signature



Signature Guaranteed:

         Signatures must be guaranteed by a member firm of a registered national
securities exchange, a member of the National Association of Securities Dealers,
Inc., or a commercial bank or trust company having an office or correspondent in
the United States.

- -------------------------------------------

         The  undersigned  hereby  certifies  that the Rights  evidenced by this
Right  Certificate  are not  beneficially  owned by an  Acquiring  Person  or an
Affiliate or Associate thereof (as defined in the Rights Agreement).

                                      Signature


- -------------------------------------------



                                       A-6


<PAGE>

             Form of Reverse Side of Right Certificate -- continued


                          FORM OF ELECTION TO PURCHASE

                  (To be executed if holder desires to exercise
                  Rights represented by the Right Certificate.)


To:  COVANCE INC.

         The undersigned hereby irrevocably elects to exercise            Rights
represented by this Right  Certificate to purchase the Preferred Shares issuable
upon the  exercise  of such  Rights  and  requests  that  certificates  for such
Preferred Shares be issued in the name of:

Please insert social security
or other identifying number


                         (Please print name and address)


If such  number of Rights  shall not be all the Rights  evidenced  by this Right
Certificate,  a new Right  Certificate for the balance  remaining of such Rights
shall be registered in the name of and delivered to:

Please insert social security
or other identifying number


                         (Please print name and address)

Dated:


                                    Signature

Signature Guaranteed:

                Signatures  must be  guaranteed by a member firm of a registered
national securities exchange, a member of the National Association of Securities
Dealers,  Inc.,  or a  commercial  bank or trust  company  having  an  office or
correspondent in the United States.


                                       A-6

<PAGE>

             Form of Reverse Side of Right Certificate -- continued

- ------------------------------------------

                The undersigned  hereby  certifies that the Rights  evidenced by
this Right  Certificate are not beneficially  owned by an Acquiring Person or an
Affiliate or Associate thereof (as defined in the Rights Agreement).


                                   Signature

- ------------------------------------------



NOTICE

         The  signature  in the  Form  of  Assignment  or Form  of  Election  to
Purchase,  as the case may be, must conform to the name as written upon the face
of this Right Certificate in every particular, without alteration or enlargement
or any change whatsoever.

         In  the  event  the  certification  set  forth  above  in the  Form  of
Assignment  or the Form of  Election  to  Purchase,  as the case may be,  is not
completed,  the Company and the Rights Agent will deem the  beneficial  owner of
the Rights  evidenced by this Right  Certificate to be an Acquiring Person or an
Affiliate or  Associate  thereof (as defined in the Rights  Agreement)  and such
Assignment or Election to Purchase will not be honored.

                                       A-6


<PAGE>

                                                                       Exhibit B






                                                      DRAFT of November 15, 1996

                              TAX SHARING AGREEMENT

         This TAX SHARING AGREEMENT (this "Agreement") is dated as of [ ], 1996,
by and among CORNING INCORPORATED, a New York corporation ("Corning"), CORNING
CLINICAL LABORATORIES INC., a Delaware corporation ("CCL"), and CORNING
PHARMACEUTICAL SERVICES INC., a Delaware corporation ("CPS").

                               W I T N E S S E T H
                  WHEREAS, Corning is the common parent of an affiliated group
of corporations which includes CCL and CPS and which group and the members
thereof file consolidated federal income tax returns as well as certain
consolidated, combined or unitary state tax returns;

                  WHEREAS, the Board of Directors of Corning has determined that
it is appropriate and desirable to effect the Distributions as defined in and
pursuant to a Transaction Agreement dated as of even date herewith between
Corning, Corning Life Sciences Inc., a Delaware corporation ("CLSI"), CCL, and
CPS (the "Transaction Agreement"), subject to the satisfaction or waiver of the
conditions set forth in the Transaction Agreement; and

                  WHEREAS, the parties hereto desire to set forth their
agreements with regard to their respective liabilities for federal, state, local
and foreign taxes for periods before and after the Distributions and to provide
for certain other tax matters.

                  NOW, THEREFORE, in consideration of the mutual agreements,
provisions and covenants contained in this Agreement, the parties hereby agree
as follows:

                                    ARTICLE 1
                                   DEFINITIONS

         SECTION 1.01. General. As used in this Agreement, the following terms
shall have the following meanings (such meanings to be equally applicable to
both the singular and plural forms of the terms defined):

<PAGE>

         "Affiliate" shall mean, when used with respect to a specified person,
another person that directly, or indirectly through one or more intermediaries,
will control, or will be controlled by or will be under common control with the
person specified immediately following the Distribution Date.

         "Agreement"  shall have the meaning described in the above preamble.

         "Carryback Item"  shall have the meaning as described in Section
5.01(b) below.

         "CCL"  shall have the meaning as described in the preamble to this
Agreement.

         "CCL Companies" shall mean, collectively, CCL and each Subsidiary of
CCL, other than CPS and any Subsidiary of CPS.

         "CCL Distribution" shall mean the distribution by Corning to the
Corning shareholders of the stock of CCL as more particularly described in the
Transaction Agreement.

         "CCL Domestic Companies" shall mean, collectively, each CCL Company
incorporated or organized under the laws of one of the respective States of the
United States.

         "CCL Group" shall mean the affiliated group of corporations as defined
in Section 1504(a) of the Code of which CCL is the common parent, not including
CPS or any member of the CPS Group and determined as if the capital stock of CCL
is widely held.

         "CCL Returns"  shall have the meaning as described in Section 2.03
below.

         "CCL Return Period" shall mean a taxable period to which this Agreement
applies and for which a CCL Return is filed.

         "CCL Separate Liability" shall have the meaning as described in
Section 4.01.

         "CI Consolidated Return" shall mean any consolidated federal income tax
return or amendment thereof of the CI Group which includes one or more of the
CCL Domestic Companies or the CPS Domestic Companies.

         "CI Consolidated Return Period" shall mean a taxable period to which
this Agreement applies and for which a CI Consolidated Return is filed.

         "CI Group" shall mean the affiliated group of corporations as defined
in Section 1504(a) of the Code of which Corning is the common parent.

                                       2

<PAGE>

         "CI Group Benefit Amount" shall have the meaning as described in
Section 4.04(b) hereof.

         "CI State, Local and Foreign Returns" shall have the meaning as
described in Section 2.02 below.

         "CI State, Local and Foreign Return Period" shall mean a taxable period
to which this Agreement applies and for which a CI State, Local and Foreign
Return is filed.

         "Code"  shall mean the Internal Revenue Code of 1986, as amended.

         "Corning"  shall have the meaning as described in the preamble to this
Agreement.

         "Corning Subsidiary" shall mean any subsidiary of Corning other than
any of the CPS Companies and the CCL Companies.

         "CPS"  shall have the meaning as described in the preamble to this
Agreement.

         "CPS Companies"  shall mean, collectively, CPS and each Subsidiary of
CPS.

         "CPS Distribution" shall mean the distribution by CCL to the CCL
shareholders of the stock of CPS as more particularly described in the
Transaction Agreement.

         "CPS Domestic Companies" shall mean, collectively, each CPS Company
incorporated or organized under the laws of one of the respective States of the
United States. "CPS Group" shall mean the affiliated group of corporations as
defined in Section 1504(a) of the Code of which CPS is the common parent and
determined as if the capital stock of CPS is widely held.

         "CPS Returns"  shall have the meaning as described in Section 2.04
below.

         "CPS Return Period" shall mean a taxable period to which this Agreement
applies and for which a CPS Return is filed.

         "CPS Separate Liability" shall have the meaning as described in Section
4.01 below.

         "Distributions" shall mean the CCL Distribution, the CPS Distribution
and any transfers relating to the CCL Distribution or the CPS Distribution.

         "Distribution Date" shall have the meaning as described in the
Transaction Agreement.

         "IRS" shall mean the Internal Revenue Service.

         "IRS Penalty Rate" small mean the rate of interest imposed from time to
time on underpayments of income tax pursuant to Code section 6621.

                                       3

<PAGE>

         "IRS Ruling" shall mean the ruling issued by the IRS which states the
tax treatment of the Distributions and related transactions.

         "person" shall mean any natural person, corporation, business trust,
joint venture, association, company, partnership or government, or any agency or
political subdivision thereof.

         "Separate CPS/CCL Liability" shall have the meaning as described in
Section 4.02 below.

         "Separate Returns" shall have the meaning as described in Section 2.04
below.

         "Spin-Off Tax Indemnification Agreements" shall mean the Spin-Off Tax
Indemnification Agreements dated of even date herewith between or among two or
more of Corning, CCL and CPS.

         "Subsidiary" shall have the meaning as described in the Transaction
Agreement.

         "Tax" or "Taxes" shall mean all federal, state, local and foreign gross
or net income, gross receipts, withholding, franchise, transfer, estimated or
other tax or similar charges and assessments, including all interest, penalties
and additions imposed with respect to such amounts.

         "Temporary Differences" attributable to any entity shall mean (a) any
single item of income or deduction in a CI Consolidated Return in respect of any
tax period that should reverse in one or more subsequent tax periods assuming
proper tax treatment and no change in law or in the tax accounting policies of
such entity (each an "Originating Temporary Difference") or (b) the partial or
complete reversal of an Originating Temporary Difference.

         "Transaction Agreement" shall have the meaning as described on page 1
of this Agreement.

         SECTION 1.02. CLSI. For all tax periods ending before or on the
Distribution Date, references herein to CCL shall include CLSI, which will be
merged into CCL prior to the Distribution Date pursuant to the Transaction
Agreement.

                                       4

<PAGE>

                                    ARTICLE 2
                                TAX RETURN FILING

         SECTION 2.01. CI Consolidated Returns. Corning shall prepare and file
with the IRS all CI Consolidated Returns and amendments thereto required to be
filed by the CI Group for all tax periods beginning before or on the
Distribution Date. Such returns shall include all income, gains, losses,
deductions and credits of the CCL Domestic Companies and the CPS Domestic
Companies. Corning shall make all decisions relating to the preparation and
filing of such returns, subject to the approval of CCL and CPS, which approval
shall not be withheld unless no reasonable basis exists for the decisions made
by Corning in respect of such return. CCL and CPS further agree to, and
respectively agree to compel the CCL Domestic Companies and the CPS Domestic
Companies to, file or join in the filing of such authorizations, elections,
consents and other documents, and take such other actions as may be necessary or
appropriate, in the opinion of Corning, to carry out the purposes and intent of
this Section 2.01, provided that such actions are not inconsistent with this
Agreement or the Spin-Off Tax Indemnification Agreements. CCL and CPS each shall
furnish Corning at least sixty (60) days before the due date (including
extensions) of any such CI Consolidated Return with its completed section of
such CI Consolidated Return, prepared in accordance with this Agreement, in
accordance with instructions from Corning and in a manner consistent with prior
returns, except to the extent otherwise required by the Spin-Off Tax
Indemnification Agreements. CCL and CPS each shall also furnish Corning work
papers and other such information and documentation as is reasonably requested
by Corning with respect to the CCL Companies and the CPS Companies. At Corning's
request, major items of income, deduction, gain and loss selected by Corning for
inclusion in the CI Consolidated Returns and relating to CCL Domestic Companies
and CPS Domestic Companies shall have been reviewed and approved prior to
submission to Corning by a nationally recognized accounting firm or law firm
with expertise sufficient to address the issues presented mutually acceptable to
Corning and the party or parties submitting such information. Corning and the
other party or parties submitting such information shall each pay an equal share
of the cost of such review.

                                       5

<PAGE>

         SECTION 2.02. CI State, Local and Foreign Returns. For any taxable
period beginning before or on the Distribution Date, Corning will prepare and
file all combined, consolidated or unitary state, local or foreign income or
franchise tax returns which are required to be filed by Corning or a Corning
Subsidiary and which include the operations conducted before or as of the
Distribution Date by (i) any of the CCL Companies or the CPS Companies, and (ii)
Corning or any Corning Subsidiary (herein, together with such returns filed for
previous periods, "CI State, Local and Foreign Returns"). Corning will timely
advise CCL and CPS of the inclusion of any of the CCL Companies and the CPS
Companies in any CI State, Local and Foreign Returns and the jurisdictions in
which such returns will be filed, which inclusion will not be inconsistent with
prior CI State, Local and Foreign Returns unless required by applicable law. CCL
and CPS will, and respectively will compel each of the CCL Companies and CPS
Companies whose tax information is included in any CI State, Local and Foreign
Return to, evidence its agreement to be included in such return on the
appropriate form and take such other action as may be appropriate, in the
opinion of Corning, to carry out the purposes and intent of this Section 2.02,
provided that such actions are not inconsistent with this Agreement or the
Spin-Off Tax Indemnification Agreements. CCL and CPS each shall furnish Corning
at least sixty (60) days before the due date (including extensions) of any such
CI State, Local and Foreign Return with a final copy of the information
necessary for Corning to complete such CI State, Local and Foreign Return,
prepared in accordance with instructions from Corning and in a manner consistent
with prior returns, except to the extent otherwise required by the Spin-Off Tax
Indemnification Agreements. CCL and CPS each shall also furnish Corning work
papers and other such information and documentation as is reasonably requested
by Corning.

         2.03 CCL Returns. For any taxable period beginning before or on the
Distribution Date, CCL will prepare and file all combined, consolidated or
unitary state, local or foreign income or franchise tax returns which are
required to be filed separately by CCL or any Subsidiary of CCL, and which
include the operations conducted before or as of the

                                       6

<PAGE>

Distribution Date by any of the CCL Companies and any of the CPS Companies
(herein, together with such returns filed for previous periods, "CCL Returns").
CCL will timely advise CPS of the inclusion of any of the CPS Companies in any
CCL Returns and the jurisdictions in which such returns will be filed, which
inclusion will not be inconsistent with prior CCL Returns unless required by
applicable law. CPS will, and will compel each of the CPS Companies whose tax
information is included in any CCL Return to, evidence its agreement to be
included in such return on the appropriate form and take such other action as
may be appropriate, in the opinion of CCL, to carry out the purposes and intent
of this Section 2.03, provided that such actions are not inconsistent with this
Agreement or the Spin-Off Tax Indemnification Agreements. CPS shall furnish CCL
at least sixty (60) days before any CCL Return is due (with extensions) with a
final copy of the information necessary for CCL to complete such CCL Return,
prepared in accordance with instructions from CCL and in a manner consistent
with prior returns, except to the extent otherwise required by the Spin-Off Tax
Indemnification Agreements. CPS shall also furnish CCL work papers and other
such information and documentation as is requested by CCL.

         2.04 Separate Returns. For any taxable period ending before, on or
after the Distribution Date, each of Corning, CCL and CPS will prepare and file
all respective separate combined, consolidated or unitary state, local or
foreign income or franchise tax returns which are required to be filed
separately by such party and not otherwise described in Section 2.01, 2.02 or
2.03 above (herein, together with such returns filed for previous periods,
"Separate Returns").

                                    ARTICLE 3
                                  TAX LIABILITY

         SECTION 3.01. Corning Liability. Except to the extent otherwise
provided herein and in the Spin-Off Tax Indemnification Agreements, for each CI
Consolidated Return Period and each CI State, Local and Foreign Return Period,
Corning shall be liable for and indemnify

                                       7

<PAGE>

CCL and CPS against all taxes due in respect of all CI Consolidated Returns and
all CI State, Local and Foreign Returns, subject to reimbursement from CCL and
CPS respectively as contemplated by Article 4.

         SECTION 3.02. State, local and foreign and separate return liability.
Except to the extent otherwise provided herein and in the Spin-Off Tax
Indemnification Agreements, (a) Corning will pay all taxes due on CI State,
Local and Foreign Returns, subject to appropriate reimbursement by CCL and CPS
respectively for liabilities for state, local and foreign returns as
contemplated by Article 4; (b) CCL will pay all taxes due on returns required to
be filed by CCL by Sections 2.03 and 2.04 hereof, subject to appropriate
reimbursement by CPS as contemplated by Article 4; and (c) CPS will pay all
taxes due on returns required to be filed by CPS by Section 2.04 hereof.

         SECTION 3.03. Taxes resulting from the failure of either Distribution.
In the event that either the CCL Distribution or the CPS Distribution shall fail
to qualify for the tax treatment stated in the IRS Ruling, for reasons other
than those indemnified against in the Spin-Off Tax Indemnification Agreements,
any and all Taxes imposed upon or incurred by Corning, CCL or CPS as a result of
such failure (including any liability of Corning, CCL or CPS arising from Taxes
imposed on shareholders of Corning, CCL or CPS to the extent any such
shareholders successfully seek recourse against Corning, CCL or CPS on account
of such failure, or any liability for such Taxes which Corning, CCL or CPS may
assume or otherwise provide for) shall be allocated among Corning, CCL and CPS
in such a manner as will take into account the extent to which the actions or
inactions before, on or after the Distribution Date of each of Corning, CCL, CPS
and their respective Affiliates may have contributed to such failure, and
Corning, CCL and CPS each shall indemnify and hold harmless the other from and
against the Taxes so allocated to Corning, CCL and CPS, respectively. In
determining the extent to which Corning, CCL and CPS may have contributed to
such failure, all facts and circumstances shall be taken into account. If it is
determined that none of Corning, CCL or CPS contributed to the failure of such
Distribution to qualify for the tax

                                       8

<PAGE>

treatment stated in the IRS Ruling, the liability of Corning, CCL and CPS under
this Section 3.03 shall be borne by each corporation in proportion to their
relative average market capitalization as determined by the average closing
price for each of Corning, CCL and CPS common stock during the 20 trading-day
period immediately following the Distribution Date. Any payments to be made by
any of Corning, CCL or CPS to another pursuant to this Section 3.03 shall be
made in immediately available funds within ten (10) days of the receipt of
notice that a payment requiring indemnification under this Section 3.03 has been
made (or is required to be made), or if there is disagreement among the parties
as to the amount or existence of liability under this Section 3.03, within ten
(10) days of the resolution of such disagreement.

                                    ARTICLE 4
                               SEPARATE LIABILITY

         SECTION 4.01. Separate Federal Liability Computation. For all tax
periods beginning after December 31, 1995, for which CI Consolidated Returns
have not been filed by Corning as of the Distribution Date and in respect of
which Corning is required to file a CI Consolidated Return, CCL and CPS
respectively shall compute the CCL Separate Liability and the CPS Separate
Liability for the portion of such periods in which the CCL Domestic Companies
and the CPS Domestic Companies respectively are members of the CI Group. "CCL
Separate Liability" in respect of any CI Consolidated Return Period means the
federal income tax liability (including CCL's share of Corning's alternative
minimum tax if Corning is subject to alternative minimum tax for such CI
Consolidated Return Period, not to exceed Corning's consolidated alternative
minimum tax for such period) computed as of December 31, 1996, as if CCL had
filed a consolidated federal income tax return for the CCL Group in respect of
such CI Consolidated Return Period. "CPS Separate Liability" in respect of any
CI Consolidated Return Period means the federal income tax liability (including
CPS's share of Corning's alternative minimum tax if Corning is subject to
alternative minimum tax for such CI Consolidated Return Period, not to exceed
Corning's consolidated alternative minimum tax for such period) computed as of
December 31, 1996, as if CPS had filed a consolidated federal

                                       9

<PAGE>

income tax return for the CPS Group in respect of such CI Consolidated Return
Period. If, in computing the CCL Separate Liability or the CPS Separate
Liability, CCL or CPS calculates that the CCL Group or the CPS Group,
respectively, would experience a net operating loss resulting in no federal
income tax liability as of December 31, 1996, the CCL Separate Liability or the
CPS Separate Liability, as the case may be, shall be equal to a credit amount
calculated by Corning and equal to the reduction in the Federal income tax
liability of the CI Group by reason of the use of such net operating loss of the
CCL Group or the CPS Group, as the case may be, in the CI Consolidated Return
that Corning projects to be filed in respect of such period. Except as may
otherwise be required by the Spin-Off Tax Indemnification Agreements,
computations in respect of the CCL Separate Liability and the CPS Separate
Liability shall be consistent with prior CI Group returns, shall follow the tax
elections and other tax positions adopted or prescribed by Corning and shall
take into account the adjustments and modifications set forth in Section 4.03;
provided, however, that the Tax Director and/or General Counsel of each of
Corning and CCL or CPS, as the case may be, shall negotiate reasonable
modifications or alternatives to such requirements in the event that either CCL
or CPS, as the case may be, reasonably determines that such elections,
positions, adjustments or modifications would have a materially detrimental
effect on the tax obligations of CCL or CPS, as the case may be, in respect of
the current or any subsequent tax period.

         SECTION 4.02. Separate CPS/CCL Liability Computation. For all tax
periods beginning after December 31, 1995, for which CCL Returns have not been
filed by CCL as of the Distribution Date and in respect of which CCL is required
to prepare and file a CCL Return, CPS shall compute the Separate CPS/CCL
Liability for the portion of such periods in which the CPS Companies
respectively are subsidiaries of CCL. "Separate CPS/CCL Liability" in respect of
any tax period means the state, local and foreign tax liability computed as of
December 31, 1996, as if CPS had filed consolidated combined or unitary state,
local and foreign tax returns with the CPS Companies in respect of such tax
period. Except as may otherwise be required by the Spin-Off Tax Indemnification
Agreements, computations in respect of the Separate CPS/CCL Liability shall be
consistent with any prior CCL Returns,

                                       10

<PAGE>

shall follow the tax elections, positions, adjustments and modifications adopted
or prescribed by CCL and take into account adjustments and modifications similar
to those set forth in Section 4.03; provided, however, that the Tax Director
and/or General Counsel of each of CCL and CPS shall negotiate reasonable
modifications or alternatives to such requirements in the event that CPS
reasonably determines that such elections, positions, adjustments or
modifications would have a materially detrimental effect on the tax obligations
of CPS in respect of the current or any subsequent tax period.

         SECTION 4.03.  Adjustments.  In computing the liabilities under
Sections 4.01 and 4.02, CCL and CPS respectively shall take into account the
following adjustments and modifications:

                  (i)   Dividends from any member of the CI Group shall be
         eliminated;

                  (ii)  Gains or losses on intercompany transactions and
         intercompany distributions between any members of the CI Group shall be
         deferred and recognized pursuant to Treas. Reg. ss. 1.1502-13 and
         1.1502-14 and Code Section 267 and the regulations thereunder;

                  (iii) All carryforwards of tax credits (except the minimum tax
         credit), net operating losses, capital losses, charitable contributions
         and other similar items shall be determined consistent with prior CI
         Consolidated Returns;

                  (iv)  All ordinary income shall be subject to tax at the
         highest tax rate applicable to taxable ordinary income of corporations;

                  (v) Any exemption or similar item that must be prorated or
         apportioned among the component members of a controlled group of
         corporations shall not be taken into account; and

                  (vi)  Other adjustments specified by Corning shall be made.

         SECTION 4.04. Payments. In respect of each period for which liabilities
are required to be calculated pursuant to Section 4.01, CCL and Corning shall
provide for payments in respect of the CCL Separate Liability and CPS and
Corning shall provide for payments in

                                       11

<PAGE>

respect of the CPS Separate Liability, in each case effective as of December 31,
1996. In respect of each period for which liabilities are required to be
calculated pursuant to Section 4.02, CPS and CCL shall provide for payments in
respect of the Separate CPS/CCL Liability, effective as of December 31, 1996.

         SECTION 4.05. Discrepancies. (a) To the extent that the liabilities
calculated pursuant to Section 4.01 are not equal to the liabilities reported on
the actual tax returns filed in respect of the periods contemplated therein: (i)
Corning shall be liable for and shall indemnify and hold harmless the other
parties hereto against all liabilities and claims and shall receive all benefits
and refunds arising in respect of such differences that do not relate to
Temporary Differences attributable to CCL or CPS and (ii) CCL or CPS, as the
case may be, shall be liable for, make payment to Corning in respect of, and
indemnify and hold harmless the other parties hereto against all liabilities and
claims and shall receive all benefits and refunds arising in respect of such
differences that relate to Temporary Differences attributable to CCL or CPS,
respectively, in accordance with Section 7.01(b). 

         (b) To the extent that the liabilities calculated pursuant to Section
4.02 are not equal to the liabilities reported on the actual tax returns filed
in respect of the periods contemplated therein, CPS shall be liable for, make
payment to CCL in respect of, and indemnify and hold harmless the other parties
hereto against all liabilities and claims where such actual liabilities are
greater than the liabilities calculated under Section 4.02 and shall receive all
benefits and refunds arising in respect of such differences attributable to CPS
where such actual liabilities are less than the liabilities calculated under
Section 4.02.

         (c) Payments to be made to Corning ,CCL or CPS in respect of
obligations arising under this Section 4.04 shall be made no later than five
days before the due date (without extensions) of the actual return to be filed.

         SECTION 4.06. State and local returns. The liabilities of CCL and the
CCL Companies and CPS and the CPS Companies with respect to CI State, Local and
Foreign Returns in respect of tax periods beginning before or on the
Distribution Date shall be computed as of December 31, 1996, under the
principles set forth in Section 4.01 and

                                       12

<PAGE>

compensation in respect to such liabilites shall be provided to Corning in
accordance with the principles of Sections 4.04 and 4.05.

                                    ARTICLE 5
                  POST-DISTRIBUTION CARRYBACKS OF TAX BENEFITS

         SECTION 5.01(a). CI Consolidated Returns; Net Operating Losses. If for
any taxable period beginning on or after the Distribution Date, a CCL Company or
a CPS Company incurs a net operating loss that may be carried back to a CI
Consolidated Return Period, the CCL Company or the CPS Company shall make an
election to relinquish the entire carryback period with respect to any such net
operating loss. If for any taxable period beginning on or after the Distribution
Date, a CCL Company or a CPS Company is entitled to a foreign tax credit or a
deduction in respect of such foreign taxes, such CCL Company or CPS Company must
take the deduction in lieu of the foreign tax credit, unless the foreign tax
credit can be fully utilized on a return other than a CI Consolidated Return.

                  (b) Other Tax Benefits. If for any taxable period beginning on
or after the date of the CCL Distribution, a CCL Company or a CPS Company incurs
a net capital loss, business credit or other Tax attribute that must be carried
back to a CI Consolidated Return (each a "Carryback Item"), such CCL Company or
CPS Company may file a refund claim reflecting such Carryback Item only after
having obtained a written consent from Corning. In the event that such CCL
Company or CPS Company does not obtain such written consent or shall not be
eligible to file such claim under applicable law, Corning may, at the written
request and expense of such CCL Company or CPS Company, file amended returns or
refund claims reflecting such Carryback Item. Such CCL Company or CPS Company
shall be compensated for the use of such Carryback Item as follows:

                           (i) Corning shall, within thirty (30) days after
receipt thereof, pay to such CCL Company or CPS Company respectively any refunds
actually received by Corning resulting from the filing of an amended return or
refund claim with respect to such Carryback Item attributable to such company,
whether such amended return or refund claim was filed by

                                       13

<PAGE>

Corning or the CCL Company or the CPS Company, together with interest received
net of taxes with respect thereto. With respect to CCL, in the event that
Corning would have received a refund (including interest) with respect to such
claim had such refund not been offset against deficiencies, interest, or
penalties assessed against the CI Group or any member thereof (other than
deficiencies, interest or penalties (A) attributable to the operations of such
CCL Company and with respect to which such entity would otherwise be responsible
under the terms of this Agreement, (B) attributable to a taxable period of the
CI Group for which the statute of limitations has expired, (C) against which CCL
is obligated to indemnify Corning pursuant to the Spin-Off Tax Indemnity
Agreements or (D) in respect of which CCL is obligated to share payment pursuant
to Section 3.03 hereof), Corning shall pay to such CCL Company, within thirty
(30) days after receipt of notice of such offset, an amount equal to the amount
of such offset, together with interest that would have been paid to Corning if
such refund had not been offset. With respect to CPS, in the event that Corning
would have received a refund (including interest) with respect to such claim had
such refund not been offset against deficiencies, interest, or penalties
assessed against the CI Group or any member thereof (other than deficiencies,
interest or penalties (A) attributable to the operations of such CPS Company and
with respect to which such entity would otherwise be responsible under the terms
of this Agreement, (B) attributable to a taxable period of the CI Group for
which the statute of limitations has expired, (C) against which CPS is obligated
to indemnify Corning pursuant to the Spin-Off Tax Indemnity Agreements or (D) in
respect of which CPS is obligated to share payment pursuant to Section 3.03
hereof), Corning shall pay to such CPS Company, within thirty (30) days after
receipt of notice of such offset, an amount equal to the amount of such offset,
together with interest that would have been paid to Corning if such refund had
not been offset.

                           (ii) If, for any taxable period, Corning is required
to and does make a repayment to the IRS of any portion of a refund described in
this Article 5 attributable to the denial of the CCL Company or CPS Company
Carryback Item, then such CCL Company or CPS Company shall pay to Corning in
immediately available funds within ten (10) days

                                       14

<PAGE>

following the date Corning notifies such CCL Company or CPS Company of such
repayment, the amount of such repayment including interest thereon.

                           (iii) If Corning elects not to file amended returns
or refund claims reflecting a Carryback Item as to which CCL or CPS might
receive a tax benefit, Corning shall notify such CCL Company or CPS Company of
its decision and state the amount including interest which it has determined to
be the appropriate compensation for its claim, and Corning shall pay such CCL
Company or CPS Company within ten (10) days of the receipt by Corning of written
notification that the CCL Company or the CPS Company agrees with its
determination, or upon irreconcilable disagreement between such parties, upon
receipt by Corning of a written determination of a nationally recognized
accounting firm or law firm with expertise sufficient to address the issues
presented and mutually agreeable to such parties.

              (iv) Notwithstanding anything to the contrary in this Article,
before Corning files a claim for refund or a CCL Company or a CPS Company is
permitted to file a claim for refund which reflects a Carryback Item and which
would affect a CI Consolidated Return, the validity and amount of any such
Carryback Item shall be reviewed and approved by Corning and such CCL Company or
CPS Company, as applicable, and, upon irreconcilable disagreement between such
parties, by a nationally recognized accounting firm or law firm with expertise
sufficient to address the issues presented and mutually agreeable to such
parties. Each CCL Company and each CPS Company, as applicable, agrees to
reimburse Corning for its reasonable expenses incurred in reviewing, filing and
securing any refund claim made at the request of such CCL Company or CPS
Company.

                                    ARTICLE 6
                  POST-DISTRIBUTION CARRYOVERS OF TAX BENEFITS

         SECTION 6.01. CI Group items. Corning shall notify CCL and CPS as soon
as practicable after the Distribution Date of any consolidated carryover item
which may be partially or totally attributed to and carried over by a CCL
Company or a CPS Company and will notify CCL and CPS of subsequent adjustments
which may affect such carryover item.

                                       15

<PAGE>

         SECTION 6.02. CCL Group Items. CCL shall notify Corning and CPS as soon
as practicable after the Distribution Date of any consolidated carryover item
which may be partially or totally attributed to and carried over by a CPS
Company and will notify Corning and CPS of subsequent adjustments which may
affect such carryover item.
                                    ARTICLE 7
                                AUDIT ADJUSTMENTS

         SECTION 7.01. CI Consolidated, State, Local and Foreign Returns. Except
as provided in the Spin-Off Tax Indemnification Agreements and in Section 3.03
hereof, if any tax liability or refund in respect of the CI Group arises as a
result of an audit by the IRS or other taxing authority and such tax liability
or refund relates to a CI Consolidated Return or a CI State, Local and Foreign
Return filed in respect of any period commencing before or on the Distribution
Date and such liability:

         (a) does not relate to Temporary Differences attributable to CCL or
         CPS, Corning shall be liable for and shall pay any tax liabilities and
         any interest and underpayment penalties associated therewith and
         Corning shall receive any such tax refunds and any interest associated
         therewith. Any penalties or additions to tax associated with tax
         liabilities that are not underpayment penalties shall be allocated
         among Corning, CCL and CPS in the proportion to which such penalties
         are assessed to Corning, CCL and CPS, respectively, or in the event
         such penalties are not clearly assessed to any individual party or
         parties, in such a manner as will take into account the extent to which
         each may have contributed to such penalties. Corning, CCL and CPS each
         shall indemnify and hold harmless the other from and against the
         penalties so allocated to Corning, CCL and CPS, respectively; or

         (b) does relate to Temporary Differences attributable to CCL or CPS,
         and such taxing authority:

                  (i) acknowledges directly or indirectly to Corning's sole
                  satisfaction that Corning may utilize such Temporary
                  Differences in computing tax liability,

                                       16

<PAGE>

                  benefit or refunds in respect of post-Distribution Date tax
                  periods, Corning shall be liable for and shall pay any such
                  tax liability and any interest and underpayment penalties
                  associated with such tax liability and shall receive any such
                  benefit or refunds and any interest associated therewith; or

                  (ii) does not acknowledge directly or indirectly to Corning's
                  sole satisfaction that Corning may utilize such Temporary
                  Differences in computing tax liability, benefit or refunds in
                  respect of post-Distribution Date tax periods, the party
                  hereto against which the issue giving rise to such tax
                  liability is directed shall be liable for and shall pay any
                  such tax liability and any interest and underpayment penalties
                  associated with such tax liability and shall receive any such
                  benefit or refunds and any interest associated therewith; and

         any liability and any penalties or additions to tax associated with
         such tax liability that are not underpayment penalties shall be
         allocated among Corning, CCL and CPS in the proportion to which such
         penalties have been assessed by such taxing authority to Corning, CCL
         and CPS, respectively, or in the event such penalties have not been
         clearly assessed to any individual party or parties, in such a manner
         as will take into account the extent to which each may have contributed
         to such penalties, and Corning, CCL and CPS each shall indemnify and
         hold harmless the other from and against the penalties so allocated to
         Corning, CCL and CPS, respectively.

         SECTION 7.02. Non-CI Consolidated, State, Local and Foreign Returns. If
any tax liability or refunds arise in respect of any member of the CI Group
(determined before giving effect to the Distributions) as a result of an audit
by the IRS or other taxing authority and such tax liability or refund does not
relate to a CI Consolidated Return or a CI State, Local and Foreign Return, the
party hereto against which the issue giving rise to such tax liability is
directed or in favor of which such return is applicable shall be liable for and
shall pay any such tax liability and any interest and penalties associated
therewith and shall receive any such refund and any interest associated
therewith, and shall indemnify and hold harmless the other parties hereto from
and against all such liabilities and any interest and penalties related thereto.

                                       17

<PAGE>

         SECTION 7.03. Other Audit Liabilities and Refunds. Except as otherwise
provided in this Article 7 or Articles 3 or 4 hereof or in the Spin-Off Tax
Indemnification Agreements, (a) CCL or CPS, as the case may be, shall be liable
for and shall pay all tax liabilities and any interest and penalties associated
therewith, and shall receive any tax refunds and any interest associated
therewith, that arise as a result of an audit by the IRS or other taxing
authority and that relate to the business or operations of CCL or Subsidiaries
of CCL and CPS or Subsidiaries of CPS, respectively, and CCL and CPS each shall
indemnify and hold harmless Corning and each other from and against the
penalties so allocated to CCL and CPS, respectively; and (b) Corning shall be
liable for and shall pay all tax liabilities and any interest and penalties
associated therewith, and shall receive any tax refunds and any interest
associated therewith, that arise as a result of an audit by the IRS or other
taxing authority and that relate to the business or operations of Corning or
Corning Subsidiaries.

         SECTION 7.04. Expenses. Any out-of-pocket expenses (e.g., travel
expenses, accountants' fees, attorneys' fees, experts' fees, etc.) incurred by
the CI Group in connection with proposed or actual liabilities or refunds of the
type contemplated in this Article 7 shall be paid by the entities to which such
liabilities or refunds are allocated hereunder. In cases where such expenses
relate to more than one member of the CI Group or more than one party hereto,
the parties affected shall determine how such expenses shall be allocated.

                                    ARTICLE 8
                                    CONTESTS

         SECTION 8.01. CI Group Contests; Notification and communication. If a
notice of audit is given, an audit is begun, an audit adjustment is (or has
been) proposed, or any other claim is (or has been) made by any taxing authority
with respect to a tax liability that, pursuant to the terms hereof, may be
attributable to a CCL Company or a CPS Company with regard to a CI Consolidated
Return or a CI State, Local and Foreign Return, Corning shall promptly

                                       18

<PAGE>

notify CCL and CPS of such event (unless a CCL Company and a CPS Company
previously was notified directly by the relevant tax authority). Thereafter,
Corning or CCL or CPS, as the case may be, shall keep the others, on a timely
basis, informed of all material developments in connection with audits,
administrative proceedings, litigation and other similar matters that may affect
their respective tax liabilities. Failure or delay in providing notification
hereunder shall not relieve any party hereto of any obligation hereunder in
respect of any particular tax liability, except to the extent that such failure
or delay restricts the ability of such party to contest such liability
administratively or in the courts and otherwise materially and adversely
prejudices such party.

         SECTION 8.02. Group Contests; Control and Management of Claims. (a) As
among the parties hereto, Corning shall control the prosecution of any audits
and any contests in respect of any claim made by a taxing authority on audit or
in a related administrative or judicial proceeding or in respect of any refund
or credit of taxes, and shall make and prosecute other claims for refunds with
respect to any tax liability, that relates to a CI Consolidated Return Period or
a CI State, Local and Foreign Return Period. CCL or CPS, as the case may be, may
participate in such audits or contests to the extent that Corning in its sole
discretion shall deem appropriate, provided, however, that Corning shall have
the sole right to control, at Corning's expense, the prosecution of any audit,
refund claim or related administrative or judicial proceeding with respect to
those matters which could affect the CI Group's tax liability.

         (b) With respect to a tax liability or refund that, pursuant to the
provisions hereof, may be attributable to a CCL Company or a CPS Company
relating to a CI Consolidated Return Period or a CI State, Local and Foreign
Return Period, if Corning elects not to exercise its rights of control under
subsection (a) hereof, and if CCL or CPS so requests, Corning shall contest,
control and allow CCL or CPS, as the case may be, to participate to the extent
that Corning in its sole discretion shall deem appropriate, all at CCL's or
CPS's respective expense, or in the alternative shall permit CCL or CPS at its
own expense to contest and control a claim made by a taxing authority on audit
or in a related administrative or judicial

                                       19

<PAGE>

proceeding or by appropriate claim for refund or credit of taxes (or to make and
prosecute other claims for refund. CCL or CPS, as the case may be, shall pay all
out-of-pocket and other costs relating to such contests, including but not
limited to fees for attorneys, accountants, expert witnesses or other
consultants.

         (c) If asserted liabilities unrelated to the matters contemplated
herein become grouped with contests arising hereunder, the parties shall use
their respective best efforts to cause the contest arising hereunder to be the
subject of a separate proceeding.

         (d) With respect to matters arising hereunder controlled by Corning,
and where deemed necessary by Corning, CCL and CPS respectively shall compel the
relevant CCL Company or CPS Company to authorize by appropriate powers of
attorney such persons as Corning shall designate to represent such CCL Company
or CPS Company with respect to such matters. The parties hereto shall reasonably
cooperate with one another in a timely manner with respect to any matter arising
hereunder.

         (e) With respect to a particular adjustment or claim made with respect
to a CCL Company or a CPS Company that, pursuant to the provisions hereof, may
be attributable to a CCL Company or a CPS Company, to the extent, and for so
long as, Corning, in the exercise of its reasonable judgment, is satisfied that
CCL and the CCL Companies or CPS and the CPS Companies can and will meet all
their obligations under this Agreement, Corning shall not settle, compromise, or
concede such adjustment or claim without the written consent of CCL or CPS, as
the case may be, which consent shall not be unreasonably withheld.

         (f) Group contests and the control and management of matters hereunder
relating solely to CCL Returns shall be subject to the provisions of this
Section 8.02, applied as if CCL was Corning and CPS was CCL for purposes
thereof.

                                    ARTICLE 9

                                       20

<PAGE>

                 INFORMATION AND COOPERATION; BOOKS AND RECORDS

         SECTION 9.01(a). Each of CCL and CPS shall deliver to Corning, as soon
as practicable after Corning's request, and CPS shall deliver to CCL, as soon as
practicable after CCL's request, such information and data concerning the
operations conducted before or as of the Distribution Date by the CCL Companies
and the CPS Companies respectively and make available such knowledgeable
employees of the CCL Companies and CPS Companies respectively as Corning or CCL,
as the case may be, may reasonably request, including providing the information
and data required by Corning's, CCL's or CPS's customary internal tax and
accounting procedures, in order to enable each of Corning or CCL, as the case
may be, to complete and file all tax forms or reports that it may be required to
file with respect to the activities of the CCL Companies and the CPS Companies
for taxable periods ending on, prior to or including the Distribution Date, to
respond to audits by any taxing authorities with respect to such activities, to
prosecute or defend any administrative or judicial proceeding and to otherwise
enable Corning or CCL, as the case may be, to satisfy its accounting and tax
requirements. CCL and CPS shall provide office space to IRS and other tax
auditors when they are conducting on-site audits, and to employees and
representatives of Corning or CCL, as the case may be, as long as a CI
Consolidated Return Period or a CI State, Local and Foreign Return Period or a
CCL Return Period, as the case may be, is open to assessment of additional taxes
or an assessment with respect to such period is being contested. Corning shall
deliver to CCL or CPS as soon as practical after CCL's or CPS's request, and CCL
shall deliver to CPS as soon as practical after CPS's request, such information
and data concerning any tax attributes which were allocated to a CCL Company or
a CPS Company that is reasonably necessary in order to enable CCL or CPS to
complete and file all tax forms or reports that it may be required to file with
respect to such activities of the CCL Companies or the CPS Companies from and
after the Distribution Date, to respond to audits by any tax authorities with
respect to such activities, to prosecute or defend claims for taxes in any
administrative or judicial proceeding, and to otherwise enable CCL or CPS to
satisfy its

                                       21

<PAGE>

accounting and tax requirements. In addition, Corning shall make available to
CCL and CPS, and CCL shall make available to CPS, its knowledgeable employees
for such purpose.

          (b). Each CCL Company and each CPS Company shall retain all books,
records, documentation or other information relating to any CI Consolidated
Return or CI State, Local and Foreign Return, and each CPS Company shall retain
all books, records, documentation or other information relating to any CCL
Return Period, until the expiration of the applicable statute of limitations
(including any extension or waiver thereof). Upon the expiration of any statute
of limitations, the foregoing information may be destroyed or disposed of
provided that (i) the CCL Company or the CPS Company provides sixty (60) days
prior written notice to Corning or CCL, as the case may be, describing in
reasonable detail the documentation to be destroyed or disposed of and (ii)
Corning or CCL, as the case may be, agrees in writing to such destruction or
disposal. If Corning or CCL, as the case may be, objects to the proposed
destruction or disposal, then the CCL Company or the CPS Company shall promptly
deliver such materials to Corning or CCL, as the case may be, or continue to
retain such materials.

                                   ARTICLE 10
                               GENERAL PROVISIONS

         SECTION 10.01.  Effectiveness. The effectiveness of this Agreement and
the obligations and rights created hereunder are subject and conditioned upon
the completion of the Distributions pursuant to the terms of the Transaction
Agreement.

                  SECTION 10.02. Notices. All notices, requests, claims, demands
         and other communications hereunder shall be in writing and shall be
         given or made (and shall be deemed to have been duly given or made upon
         receipt) by delivery in person, by courier service (including overnight
         delivery), by cable, by telecopy confirmed by

                                       22

<PAGE>

         return telecopy, by telegram, by telex or by registered or certified
         mail (postage prepaid, return receipt requested) to the respective
         parties at the addresses (or at such other address for a party as shall
         be specified in a notice given in accordance with this Section 10.01)
         listed below:

         (a)      To Corning Incorporated:
                  One Riverfront Plaza
                  Corning, New York  14831
                  Telecopy: (607) 974-8656
                  Attn: each of the General Counsel and Tax Director

         (b)      To CCL:
                  One Malcolm Avenue
                  Teterboro, New Jersey 07608
                  Telecopy: (201) 462-4795
                  Attn: each of the General Counsel and Tax Director

         (c)      To CPS:
                  210 Carnegie Center
                  Princeton, New Jersey 08540-6233
                  Telecopy:(609) 452-9865
                  Attn: each of the General Counsel and Tax Director

         SECTION 10.03. Complete Agreement; Construction. This Agreement is
intended to provide rights, obligations and covenants in respect of Taxes and,
together with the Spin-Off Tax Indemnification Agreements, shall supersede all
prior agreements and undertakings, both written and oral, between the parties
with respect to the subject matter hereof and thereof. In the event provisions
of this Agreement are inconsistent with provisions in a Spin-Off Tax
Indemnification Agreement, the provisions in the Spin-Off Tax Indemnification
Agreement shall control, except in cases where this construction would provide a
duplicate benefit.

         SECTION 10.04. Counterparts. This Agreement may be executed in one or
more counterparts, and by the different parties hereto in separate counterparts,
each of which when

                                       23

<PAGE>

executed shall be deemed to be an original but all of which taken together shall
constitute one and the same agreement.

         SECTION 10.05. Waiver. The parties to this Agreement may (a) extend the
time for the performance of any of the obligations or other acts of the other
party or parties, (b) waive any inaccuracies in the representations and
warranties of the other party or parties contained herein or in any document
delivered by the other party or parties pursuant hereto or (c) waive compliance
with any of the agreements or conditions of the other party or parties contained
herein. Any such extension or waiver shall be valid only if set forth in an
instrument in writing signed by the party to be bound thereby. Any waiver of any
term or condition shall not be construed as a waiver of any subsequent breach or
a subsequent waiver of the same term or condition, or a waiver of any other term
or condition, of this Agreement. The failure of any party to assert any of its
rights hereunder shall not constitute a waiver of any such rights.

         SECTION 10.06. Amendments. This Agreement may not be amended or
modified except (a) by an instrument in writing signed by, or on behalf of, the
parties or (b) by a waiver in accordance with Section 10.05.

         SECTION 10.07. Successors and Assigns. The provisions of this Agreement
shall be binding upon, inure to the benefit of and be enforceable by the parties
and their respective successors and permitted assigns. This Agreement cannot be
assigned by Corning, CCL or CPS, in each case without the consent of the other
two parties hereto.

         SECTION 10.08. Subsidiaries. Each of the parties hereto shall cause to
be performed, and hereby guarantees the performance of, all actions, agreements
and obligations set forth herein to be performed by any subsidiary of such party
or by any entity that is contemplated to be a subsidiary of such party on and
after the Distribution Date.

                                       24

<PAGE>

         SECTION 10.09. Third Party Beneficiaries. This Agreement shall be
binding upon and inure solely to the benefit of the parties hereto and their
respective subsidiaries, and nothing herein, express or implied, is intended to
or shall confer upon any third parties any legal or equitable right, benefit or
remedy of any nature whatsoever under or by reason of this Agreement.

         SECTION 10.10. Headings. The descriptive headings contained in this
Agreement are for convenience of reference only and shall not affect in any way
the meaning or interpretation of this Agreement.

         SECTION 10.11. Specific Performance. The parties hereto agree that
irreparable damage would occur in the event any provision of this Agreement was
not performed in accordance with the terms hereof and that the parties shall be
entitled to specific performance of the terms hereof, in addition to any other
remedy at law or equity.

         SECTION 10.12. Governing Law. This Agreement shall be governed by, and
construed in accordance with, the laws of the State of New York, applicable to
contracts executed in and to be performed entirely within that state.

         SECTION 10.13. Arbitration. Any conflict or disagreement arising out of
the interpretation, implementation, or compliance with the provisions of this
Agreement shall be finally settled pursuant to the provisions of Article V
(Dispute Resolution) of the Transaction Agreement, which provisions are
incorporated herein by reference.

         SECTION 10.14. Severability. If any term or other provision of this
Agreement is invalid, illegal or incapable of being enforced by any law or
public policy, all other terms and provisions of this Agreement shall
nevertheless remain in full force and effect so long as the economic or legal
substance of the transactions contemplated hereby is not affected in any manner
materially adverse to any party. Upon such determination that any term or other

                                       25

<PAGE>

provision is invalid, illegal or incapable of being enforced, the parties hereto
shall negotiate in good faith to modify this Agreement so as to effect the
original intent of the parties as closely as possible in an acceptable manner in
order that the transactions contemplated hereby are consummated as originally
contemplated to the greatest extent possible.

                                       26

<PAGE>

                  IN WITNESS WHEREOF, the parties have caused this Agreement to
be executed as of the date first written above by their respective officers
thereunto duly authorized.

                                        CORNING INCORPORATED,

                                        by ____________________________________
                                           Name:
                                           Title:

                                        CORNING CLINICAL LABORATORIES INC.,

                                        by ____________________________________
                                           Name:
                                           Title:

                                        CORNING PHARMACEUTICAL SERVICES INC.,

                                        by ____________________________________
                                           Name:
                                           Title:

MPE
taxshar.009

                                       27



                                                        Draft of August 23, 1996

               CORNING/CPS SPIN-OFF TAX INDEMNIFICATION AGREEMENT

                  This SPIN-OFF TAX INDEMNIFICATION AGREEMENT ("Agreement") is
made and entered into this __ day of ______, 1996, by and among CORNING
INCORPORATED, a New York corporation ("Corning") and CORNING PHARMACEUTICAL
SERVICES INC., a Delaware corporation ("CPS").

                                   WITNESSETH

                  WHEREAS, Corning is the common parent of an affiliated group
of corporations within the meaning of Code1 Section 1504 which includes CPS;

                  WHEREAS, Corning has determined to effect the Distributions
pursuant to a Transaction Agreement and Plan of Reorganization (the "Transaction
Agreement") dated of even date herewith;

                  WHEREAS, the IRS has issued the IRS Ruling which states the 
tax treatment of the Distributions and the Other Transactions; and

                  WHEREAS, the parties hereto are entering into this Agreement
to indemnify Corning as hereinafter provided in the event the Distributions or
the Other Transactions fail to qualify for the tax treatment stated in the IRS
Ruling due to actions by CPS.

                  NOW, THEREFORE, in consideration of the mutual agreements,
provisions and covenants contained in this Agreement, the parties hereby agree
as follows:

                    ARTICLE 1: Representations and Covenants

                  SECTION 1.01. Representations. (a) CPS has reviewed the
materials submitted to the IRS in connection with the IRS Ruling and, to the
best of CPS's knowledge, these materials, including, without limitation, any
statements and representations concerning CPS, its business, operations capital
structure and/or organization, are complete and accurate in all material
respects. CPS shall, and shall cause each member of the CPS Group, to comply
with each such representation and statement concerning CPS and the CPS Group
made in the materials so submitted, the IRS Ruling and any subsequent IRS
ruling, including without limitation, statements as to the creation, funding and
operation of employee compensation

- --------

1 Capitalized terms not defined herein have the meaning given to them in Annex
A.

<PAGE>

plans by CPS. With respect to any representation or statement made by or on
behalf of CPS in connection with the IRS Ruling and any subsequent IRS ruling
and to the extent such representation or statement relates to future actions or
events under their control, neither CPS nor any member of the CPS Group will
take any action during the Restricted Period that would have caused such
representation or statement to be untrue if CPS had planned or intended to take
such action at the time such representation or statement was made by or on
behalf of CPS.

                  (b) CPS hereby represents and warrants to Corning that CPS has
no present intention to undertake any of the transactions set forth in Section
1.02 (a) (iii) or to cease to engage in the active conduct of the trade or
business (within the meaning of Section 355(b)(2) of the Code) of providing
pharmaceutical services.

                  SECTION 1.02. Covenants. (a) CPS covenants and agrees with
Corning that during the Restricted Period:

                  (i) CPS will continue to engage in the pharmaceutical services
business in the U.S. and will continue to maintain in the U.S. a substantial
portion of its assets and business operations as they existed prior to the
Distributions, provided that the foregoing shall not be deemed to prohibit CPS
from entering into or acquiring other businesses or operations which may or may
not be consistent with its business and operations as they existed prior to the
Distributions so long as CPS continues to engage in such pharmaceutical services
business in the U.S. and continues to so maintain such substantial portion in
the U.S.;

                  (ii) CPS will continue to manage and to own (A) directly
assets which represent at least fifty percent (50%) of the Gross Assets which
CPS managed and owned directly immediately after the Distributions, and (B)
directly or indirectly through one or more entities, assets which represent at
least 50% of the Gross Assets which CPS owned indirectly through one or more
entities immediately after the Distributions;

                  (iii) except as provided in Section 1.02(c), neither CPS, nor
any of its Affiliates nor any of their respective, directors, officers or other
representatives will undertake, authorize, approve, recommend, permit,
facilitate, or enter into any contract, or consummate any transaction with
respect to: (A) the issuance of CPS Common Stock (including options, warrants,
rights or securities exercisable for, or convertible into, CPS Common Stock) in
a single transaction or in a series of related or unrelated transactions or
otherwise or in the aggregate which would exceed (or could exceed if any such
options, warrants or rights were exercised or such securities were converted)
fifty percent (50%) when expressed as a percentage of the outstanding shares of
CPS Common Stock immediately following the Distributions; (B) the issuance of
any class or series of capital stock or any other instrument (other than CPS
Common Stock and options, warrants, rights or securities exercisable for, or
convertible into, CPS Common Stock) that would constitute equity for federal tax
purposes (such classes or series of capital stock and other instruments being
referred to herein as

                                       2
<PAGE>

"Disqualified CPS Stock"); (C) the issuance of any options, rights, warrants,
securities or similar arrangements exercisable for, or convertible into,
Disqualified CPS Stock; (D) any redemptions, repurchases or other acquisitions
of capital stock or other equity interests in CPS in a single transaction or a
series of related or unrelated transactions, unless such redemptions,
repurchases or other acquisitions (1) satisfy the following requirements: (a)
there is a "sufficient business purpose" (within the meaning of Section
4.05(1)(b) of Revenue Procedure 96-30) for the transaction, (b) the stock to be
purchased, redeemed or otherwise acquired is widely held, (c) the stock
purchases or other acquisitions will be made on the open market, and (d) the
amount of stock purchases, redemption, or other acquisitions in a single
transaction or in a series of related or unrelated transactions will not exceed
an amount of stock representing twenty percent (20%) of the outstanding stock of
CPS immediately following the Distributions; or (2) are made in connection with
employee equity compensation plans of CPS and do not result, individually or in
the aggregate, in the acquisition of more than ten percent (10%) of the voting
power in respect of the outstanding stock of CPS immediately following the
Distributions, (E) the dissolution, merger , or complete or partial liquidation
of CPS or any announcement of such action; or (F) the waiver, amendment,
termination or modification of any provision of the CPS Rights Plan in
connection with, or in order to permit or facilitate, any acquisition or
proposed acquisition of Beneficial Ownership of capital stock or other equity
interest in CPS.

                  (b) In addition to the other representations, warranties,
covenants and agreements set forth in this Agreement, CPS and the CPS Group will
take, or refrain from taking, as the case may be, such actions as Corning may
reasonably request during the Ruling Period as necessary to insure that the
Distributions and the Other Transactions qualify for the tax treatment stated in
the IRS Ruling, including, without limitation, such actions as Corning
determines may be necessary to obtain and preserve the IRS Ruling or any
subsequent IRS ruling on which the parties can rely. Without limiting the
generality of the foregoing, CPS and the CPS Group shall cooperate with Corning
if Corning determines to obtain additional IRS rulings pertaining to whether any
actual or proposed change in facts and circumstances affects the tax status of
the Distributions or the Other Transactions.

                  (c) Following the six-month anniversary of the Distribution
Date, CPS and its Affiliates may take any action or engage in conduct otherwise
prohibited by Section 1.02 so long as prior to such action or conduct, as the
case may be, Corning or CPS receives (A) a ruling from the IRS in form and
substance reasonably satisfactory to Corning and upon which Corning can rely to
the effect that the proposed action or conduct, as the case may be, will not
cause the Distributions or the Other Transactions to fail to qualify for the tax
treatment stated in the IRS Ruling or otherwise to be taxable for federal income
tax purposes, or (B) an Opinion of Counsel in form and substance reasonably
satisfactory to Corning and upon which Corning can rely to the effect that the
proposed action or conduct, as the case may be, will not cause the Distributions
or the Other Transactions to fail to qualify for the tax treatment stated in the
IRS Ruling or otherwise to be taxable for federal income tax purposes.

                                       3
<PAGE>

                      ARTICLE 2: CPS Indemnity Obligations

                  SECTION 2.01. Tax Indemnities. (a) If CPS, or another member
of the CPS Group (collectively the "Indemnifying Party") shall take any action
prohibited by Article 1 or shall violate a representation or covenant contained
in Article 1, and either of the Distributions or any of the Other Transactions
shall fail to qualify for the tax treatment stated in the IRS Ruling primarily
as a result of such action or violation, then the Indemnifying Party shall
(jointly or severally) indemnify and hold harmless Corning and each member of
the Corning Group (collectively the "Indemnified Party") against any and all
Taxes imposed upon or incurred by the Indemnified Party as a result of the
failure, including, without limitation, any liability of the Indemnified Party
arising from Taxes imposed on shareholders of Corning to the extent any
shareholder or shareholders of Corning successfully seek recourse against the
Indemnified Party on account of any such failure, or any liability for such
Taxes which the Indemnified Party may assume or otherwise provide for.

                  (b) Notwithstanding anything to the contrary set forth in this
Agreement, if, during the Restricted Period, any Person or Group of Affiliated
Persons or Associated Persons acquires Beneficial Ownership of twenty percent
(20%) or more of CPS Common Stock (or any other class of outstanding CPS stock)
or commences a tender or other purchase offer for the capital stock of CPS upon
consummation of which such Person or Group of Affiliated Persons or Associated
Persons would acquire Beneficial Ownership of twenty percent (20%) or more of
the CPS Common Stock (or any other class of outstanding CPS stock) and either of
the Distributions or any of the Other Transactions shall fail to qualify for the
tax treatment stated in the IRS Ruling primarily as a result of such acquisition
or tender or other purchase offer; then the Indemnifying Party shall indemnify
and hold harmless the Indemnified Party against any and all Taxes imposed upon
or incurred by the Indemnified Party and/or its shareholders as a result of the
failure of either Distribution or the Other Transactions to so qualify.

                  (c) The Indemnified Party shall be indemnified and held
harmless under Section 2.01(a) without regard to the fact that the Indemnified
Party may have received a supplemental ruling from the IRS or an Opinion of
Counsel as contemplated by Section 1.02(c). The Indemnified Party shall be
indemnified and held harmless under Section 2.01(b) without regard to whether an
acquisition of Beneficial Ownership results from a transaction which is not
prohibited under Article 1.

                                       4
<PAGE>

                   ARTICLE 3: Calculation of Indemnity Amounts

                  SECTION 3.01.  Amount of Indemnified Liability.
The amount indemnified against under Article 2 ("Indemnified Liability") for a
tax based on or determined with reference to income shall be deemed to be the
amount of the tax computed by multiplying (i) the taxing jurisdiction's highest
marginal tax rate applicable to taxable income of corporations such as the
Indemnified Party on income of the character subject to tax and indemnified
against under Article 2 for the taxable period in which the Distributions occur,
times (ii) the gain or income of the Indemnified Party which is subject to tax
in the taxing jurisdiction and indemnified against under Article 2. In the case
of an Indemnified Liability attributable to a payment owed to a shareholder or
shareholders of Corning, the amount of the Indemnified Liability shall be equal
to the amount so owed, including without limitation, interest, costs, additions,
expenses and penalties. All amounts payable under this Agreement shall be paid
on an after-tax basis. If an Indemnified Liability is of a type that constitutes
a deduction from income in any taxable period in determining the Indemnified
Party's liability for a tax based upon or determined with reference to income,
the amount of the Indemnified Liability shall be reduced by the reduction in the
tax liability of the Indemnified Party.

                          ARTICLE 4: Procedural Matters

                  SECTION 4.01. General. (a) If either the Indemnified Party or
the Indemnifying Party receives any written notice of deficiency, claim or
adjustment or any other written communication from a taxing authority that may
result in an Indemnified Liability, the party receiving such notice or
communication shall promptly give written notice thereof to the other party,
provided that any delay by the Indemnified Party in so notifying an Indemnifying
Party shall not relieve the Indemnifying Party of any liability hereunder,
except to the extent (i) such delay restricts the ability of the Indemnifying
Party to contest the resulting Indemnified Liability administratively or in the
courts in accordance with Section 4.02 and (ii) the Indemnifying Party is
materially and adversely prejudiced by such delay.

                  (b) The parties hereto undertake and agree that from and after
such time as they obtain knowledge that any representative of a taxing authority
has begun to investigate or inquire into either Distribution or any of the Other
Transactions (whether or not such investigation or inquiry is a formal or
informal investigation or inquiry), the party obtaining such knowledge shall (i)
notify the other party thereof, provided that any delay by the Indemnified Party
in so notifying the Indemnifying Party shall not relieve the Indemnifying Party
of any liability hereunder (except to the extent (A) such delay restricts the
ability of the Indemnifying Party to contest the resulting Indemnified Liability
administratively or in the courts in accordance with Section 4.02 and (B) the
Indemnifying Party is materially and adversely prejudiced by such delay), (ii)
consult with the other party from time to time as to the conduct of such
investigation or inquiry, (iii) provide the other party with copies of all
correspondence with such taxing authority or any representative thereof
pertaining to such investigation or inquiry, and (iv) arrange for a
representative of the other party to be present at

                                       5
<PAGE>

all meetings with such taxing authority or any representative thereof pertaining
to such investigation or inquiry.

                  SECTION 4.02. Contests. (a) Provided that (i) the Indemnifying
Party shall furnish the Indemnified Party with evidence reasonably satisfactory
to the Indemnified Party of its ability to pay the full amount of the
Indemnified Liability and (ii) the Indemnifying Party acknowledges in writing
that the asserted liability is an Indemnified Liability, the Indemnifying Party
shall assume and direct the defense or settlement of any hearing, arbitration,
suit or other proceeding (each a "Proceeding") commenced, filed or otherwise
initiated or convened to investigate or resolve the existence and extent of such
liability.

                  (b) If the Indemnified Liability is grouped with other
unrelated asserted liabilities or issues in the Proceeding, the parties shall
use their respective best efforts to cause the Indemnified Liability to be the
subject of a separate proceeding. If such severance is not possible, the
Indemnifying Party shall assume and direct and be responsible only for the
matters relating to the Indemnified Liability.

                  (c) If at any time during a Proceeding controlled by the
Indemnifying Party pursuant to Section 4.02(a) the Indemnifying Party fails to
provide evidence reasonably satisfactory to the Indemnified Party of its ability
to pay the full amount of the Indemnified Liability or the Indemnified Party
reasonably determines, after due investigation, that the Indemnifying Party
could not pay the full amount of the Indemnified Liability, then the Indemnified
Party may assume control of the Proceedings upon seven (7) days written notice.

                  (d) The Indemnifying Party shall pay all out-of-pocket
expenses and other costs related to the Indemnified Liability, including but not
limited to fees for attorneys, accountants, expert witnesses or other
consultants retained by the Indemnifying Party and/or the Indemnified Party,
other than fees for attorneys, accountants, expert witnesses or other
consultants retained solely by the Indemnified Party and incurred at any time
during which the Indemnifying Party is controlling and directing the Proceeding
in respect of which such fees are incurred. To the extent that any such expenses
and other costs have been or are paid by an Indemnified Party, the Indemnifying
Party shall promptly reimburse the Indemnified Party therefor.

                  (e) The Indemnifying Party shall not pay (unless otherwise
required by a proper notice of levy and after prompt notification to the
Indemnified Party of receipt of notice and demand for payment), settle,
compromise or conceded any portion of the Indemnified Liability without the
written consent of the Indemnified Party, which consent shall not be
unreasonably withheld. The Indemnifying Party shall, on a timely basis, keep the
Indemnified Party informed of all developments in the Proceeding and provide the
Indemnified Party with copies of all pleadings, briefs, orders, and other
written papers.

                                       6
<PAGE>

                  (f) Any Proceeding which is not controlled or which is no
longer controlled by the Indemnifying Party pursuant to Section 4.02 shall be
controlled and directed exclusively by the Indemnified Party, and any related
out-of-pocket expenses and other costs incurred by the Indemnified Party,
including but not limited to, fees for attorneys, accountants, expert witnesses
or other consultants, shall be reimbursed by the Indemnifying Party. The
Indemnified Party will not be required to pursue the claim in the federal
district court, Court of Claims or any state court if as a prerequisite to such
Court's jurisdiction, the Indemnified Party is required to pay the asserted
liability unless the funds necessary to invoke such jurisdiction are provided by
the Indemnifying Party.

                  SECTION 4.03.  Time and Manner of Payment.  The
Indemnifying Party shall pay to the Indemnified Party the amount of the
Indemnified Liability and any expenses or other costs indemnified against (less
any amount paid directly by the Indemnifying Party to the taxing authority) no
less than (7) business days prior to the date payment of the Indemnified
Liability is to be made by any party to the taxing authority. Such payment shall
be paid by wire transfer of immediately available funds to an account designated
by the Indemnified Party by written notice to the Indemnifying Party prior to
the due date of such payment. If the Indemnifying Party delays making payment
beyond the due date hereunder, such party shall pay interest on the amount
unpaid at the IRS Penalty Rate for each day and the actual number of days for
which any amount due hereunder is unpaid.

                  SECTION 4.04. Refunds. In connection with this Agreement,
should an Indemnified Party receive a refund in respect of amounts paid by an
Indemnifying Party to any taxing authority on its behalf, or should any such
amounts that would otherwise be refundable to the Indemnifying Party be applied
by the taxing authority to obligations of the Indemnified Party unrelated to an
Indemnified Liability, then such Indemnified Party shall, promptly following
receipt (or notification of credit), remit such refund and any related interest
to the Indemnifying Party.

                  SECTION 4.05. Cooperation. The parties shall cooperate with
one another in a timely manner in any administrative or judicial proceeding
involving any matter that may result in an Indemnified Liability.

                          ARTICLE 5: General Provisions

                  SECTION 5.01. Notices. All notices, requests, claims and other
communications hereunder shall be in writing and shall be given or made (and
shall be deemed to have been duly given or made upon receipt) by delivery in
person, by courier service, by cable, by telecopy, by telegram, by telex or by
registered or certified mail (postage prepaid, return receipt requested) to the
respective parties at the addresses (or at such other address for a party as
shall be specified in a notice given in accordance with this Section 5.01)
listed below:

                                       7

<PAGE>

                  To Corning:
                           One Riverfront Plaza
                           Corning, New York  14831
                           Telecopy:
                           Attn: General Counsel

                  To CPS:
                           Carnegie Center
                           Princeton, New Jersey  08540-6233
                           Telecopy:
                           Attn: General Counsel

                  SECTION 5.02.  Miscellaneous.  This Agreement, including the
attachments, shall constitute the entire agreement between the parties hereto
with respect to the subject matter hereof and shall supersede all prior
agreements and undertakings, both written and oral, between the parties with
respect to the subject matter hereof and thereof. This Agreement may be executed
in one or more counterparts, and by the different parties hereto in separate
counterparts, each of which when executed shall be deemed to be an original but
all of which taken together shall constitute one and the same agreement. This
Agreement may not be amended or modified except (a) by an instrument in writing
signed by, or on behalf of, the parties or (b) by a waiver in accordance with
Section 5.03. This Agreement shall be binding upon and inure solely to the
benefit of the parties hereto and their respective subsidiaries, and nothing
herein, express or implied, is intended to or shall confer upon any third
parties any legal or equitable right, benefit or remedy of any nature whatsoever
under or by reason of this Agreement.

                  SECTION 5.03. Waiver. The parties to this Agreement may (a)
extend the time for the performance of any of the obligations or other acts of
the other party or parties, (b) waive any inaccuracies in the representations
and warranties of the other party or parties contained herein or in any document
delivered by the other party or parties pursuant hereto or (c) waive compliance
with any of the agreements or conditions of the other party or parties contained
herein. Any such extension or waiver shall be valid only if set forth in an
instrument in writing signed by the party to be bound thereby. Any waiver of any
term or condition shall not be construed as a waiver of any subsequent breach or
a subsequent waiver of the same term or condition, or a waiver of any other term
or condition, of this Agreement. The failure of any party to assert any of its
rights hereunder shall not constitute a waiver of any such rights.

                  SECTION 5.04.  Successors and Assigns.  The provisions of
this Agreement shall be binding upon, inure to the benefit of and be enforceable
by the parties and their respective successors and permitted assigns.
Notwithstanding the previous sentence, CPS shall not assign this Agreement or
any rights, interests or obligations hereunder, or delegate performance of any
of its obligations hereunder, without the consent of Corning.

                                       8
<PAGE>

                  SECTION 5.05.  Specific Performance.  The parties hereto
agree that irreparable damage would occur in the event any provision of this
Agreement was not performed in accordance with the terms hereof and that the
parties shall be entitled to specific performance of the terms hereof, in
addition to any other remedy at law or equity.

                  SECTION 5.06.  Governing Law and Severability.
This Agreement shall be governed by, and construed in accordance with, the laws
of the State of New York, applicable to contracts executed in and to be
performed entirely within that state. If any term or other provision of this
Agreement is invalid, illegal or incapable of being enforced by any law or
public policy, all other terms and provisions of this Agreement shall
nevertheless remain in full force and effect so long as the economic or legal
substance of the transactions contemplated hereby is not affected in any manner
materially adverse to any party. Upon such determination that any term or other
provision is invalid, illegal or incapable of being enforced, the parties hereto
shall negotiate in good faith to modify this Agreement so as to effect the
original intent of the parties as closely as possible in an acceptable manner in
order that the transactions contemplated hereby are consummated as originally
contemplated to the greatest extent possible.

         IN WITNESS WHEREOF, the parties have caused this Agreement to be
executed as of the date first written above by their respective officers
thereunto duly authorized.

CORNING INCORPORATED                        CORNING PHARMACEUTICAL
                                               SERVICES INC.

By__________________________________        By_________________________________
Name:                                         Name:
Title:                                        Title:

                                       9

<PAGE>

                                                        Draft of August 12, 1996

                                     ANNEX A
                                   DEFINITIONS

"Affiliate" shall mean, when used with respect to a specified Person, another
Person that directly, or indirectly through one or more intermediaries, controls
or is controlled by or is under common control with such Person.

"Affiliated Person" shall have the meaning ascribed to such term in the
Investment Company Act of 1940, as amended, and the rules and regulations
promulgated thereunder.

"Associated Person" shall have the meaning ascribed to such term in the
Securities Exchange Act of 1934, as amended, and the rules and regulations
promulgated thereunder.

"Beneficial Ownership" shall have the meaning ascribed to such term in the
Securities Exchange Act of 1934, as amended, and the rules and regulations
promulgated thereunder.

"CCL Common Stock" shall mean the common stock, [$0.50] par value [with attached
Preferred Stock Purchase Rights] of CCL.

"CCL Distribution" shall mean the distribution by Corning to the Corning
shareholders of the CCL Common Stock.

"CCL Group" shall mean the affiliated group of corporations as defined in
Section 1504(a) of the Code of which CCL (or any successor thereto) is the
common parent, excluding CPS and the other members of the CPS Group.

"CCL Rights Plan" shall mean the Preferred Share Purchase Rights Plan of CCL as
governed by the Rights Agreement, dated as of __________, 1996, between CCL and
____________________, as Rights Agent.

"Code" shall mean the Internal Revenue Code of 1986, as amended, and the
Treasury regulations promulgated thereunder, including any comparable successor
legislation.

"Corning Group" shall mean the affiliated group of corporations as defined in
Section 1504(a) of the Code of which Corning (or any successor thereto) is the
common parent, excluding for tax periods of the Corning Group commencing
subsequent to the Distribution Date, CCL and the other members of the CCL Group
and CPS and other members of the CPS Group.

<PAGE>

"CPS Common Stock" shall mean the common stock, [$0.50] par value [with attached
Preferred Stock Purchase Rights] of CPS.

"CPS Distribution" shall mean the distribution by CCL to the CCL shareholders of
the CPS Common Stock.

"CPS Group" shall mean the affiliated group of corporations as defined in
Section 1504(a) of the Code of which CPS (or any successor thereto) is the
common parent.

"CPS Rights Plan" shall mean the Preferred Share Purchase Rights Plan of CPS as
governed by the Rights Agreement, dated as of __________, 1996, between CPS and
____________________, as Rights Agent.

"Distributions" shall mean the each of the CCL Distribution and the CPS
Distribution, including any transfers relating to the CCL Distribution or the
CPS Distribution.

"Distribution Date" shall mean such date as has been or hereafter will be
determined by Corning's Board of Directors as the date as of which the
Distributions shall be effected.

"Gross Assets" shall mean, when used with respect to a specified Person, the
fair market value of such Person's assets unencumbered by any liabilities.

"Group" shall have the meaning ascribed to such term in the Securities Exchange
Act of 1934, as amended, and the rules and regulations promulgated thereunder.

"IRS" shall mean the U.S. Internal Revenue Service.

"IRS Penalty Rate" shall mean the rate of interest imposed from time to time on
underpayments of income tax pursuant to Code section 6621.

"IRS Ruling" shall mean the private letter ruling (together with any
supplements) issued by the IRS in respect of the Ruling Request.

"Opinion of Counsel" shall mean an opinion of independent tax counsel of
recognized national standing and experienced in the issues to be addressed and
otherwise reasonably acceptable to Corning, which sets forth an Unqualified Tax
Opinion in form and substance satisfactory to Corning. In no event shall Corning
be required to conclude that an opinion is satisfactory if there is any risk,
however remote, that the transaction which is the subject of the opinion will
cause either of the Distributions to be taxable to any extent under the Code.

"Other Transactions" shall mean the transactions related to the Distributions
and described in Parts I through IV of the Ruling Request.

                                       2

<PAGE>

"Person" shall mean any natural person, corporation, business trust, joint
venture, association, company, partnership or government, or any agency or
political subdivision thereof.

"Restricted Period" shall mean the two year period following the Distribution
Date.

"Ruling Period" shall mean the period commencing on the Distribution Date and
ending on the later of (i) the third anniversary of the close of the taxable
year of Corning in which the Distributions occur, and (ii) the first anniversary
of the date on which there shall have expired all statutes of limitations in
respect of taxable periods for which Taxes might be imposed or otherwise
assessed in respect of the Distributions and the Other Transactions.

"Ruling Request" shall mean the request for rulings, as amended and
supplemented, under Section 355 of the Code, as filed on behalf of Corning on
June 17, 1996, in respect of the Distributions.

"Taxes" shall mean all federal, state, local and foreign gross or net income,
gross receipts, withholding, franchise, transfer, estimated or other taxes or
similar charges and assessments, including all interest, penalties and additions
imposed with respect to such amounts.

"Unqualified Tax Opinion" shall mean (a) an unqualified "will" opinion of tax
counsel to the effect that a transaction does not disqualify either of the
Distributions from qualifying for tax-free treatment for the shareholders of
Corning and CCL and any member of the Corning Group and the CCL Group under Code
section 355 and any other applicable sections of the Code, assuming that the
Distributions would have qualified for tax-free treatment if such transaction
did not occur. An Unqualified Tax Opinion may rely upon, and assume the accuracy
of, any representations contained in any application for a letter ruling from
the IRS, and any representations contained in an officer's certificate delivered
by an officer of Corning, CCL or CPS to such counsel.

                                       3


                                                     Draft of September 30, 1996

                 CPS/CCL SPIN-OFF TAX INDEMNIFICATION AGREEMENT

                  This SPIN-OFF TAX INDEMNIFICATION AGREEMENT ("Agreement") is
made and entered into this __ day of ______, 1996, by and among CORNING
PHARMACEUTICAL SERVICES INC., a Delaware corporation ("CPS") and CORNING
CLINICAL LABORATORIES INC., a Delaware corporation ("CCL").

                                   WITNESSETH

                  WHEREAS, Corning Incorporated, a New York corporation
("Corning"), is the common parent of an affiliated group of corporations within
the meaning of Code1 Section 1504 which includes CPS and CCL;

                  WHEREAS, Corning has determined to effect the Distributions
pursuant to a Transaction Agreement (the "Transaction Agreement") dated of even
date herewith;

                  WHEREAS, the IRS has issued the IRS Ruling which states the
tax treatment of the Distributions and the Other Transactions; and

                  WHEREAS, the parties hereto are entering into this Agreement
to indemnify CPS as hereinafter provided in the event the CPS Distribution or
the Other Transactions fail to qualify for the tax treatment stated in the IRS
Ruling due to actions by CCL.

                  NOW, THEREFORE, in consideration of the mutual agreements,
provisions and covenants contained in this Agreement, the parties hereby agree
as follows:

                    ARTICLE 1: Representations and Covenants

                  SECTION 1.01. Representations. (a) CCL has reviewed the
materials submitted to the IRS in connection with the IRS Ruling and, to the
best of CCL's knowledge, these materials, including, without limitation, any
statements and representations concerning CCL, its business, operations capital
structure and/or organization, are complete and accurate in all material
respects. CCL shall, and shall cause each member of the CCL Group, to comply
with each such representation and statement concerning CCL and the CCL Group
made in the materials so submitted, the IRS Ruling and any subsequent IRS
ruling, including without limitation, statements as to the creation, funding and
operation of employee

- --------
1 Capitalized terms not defined herein have the meaning given to them in Annex
A.

<PAGE>

compensation plans by CCL. With respect to any representation or statement made
by or on behalf of CCL in connection with the IRS Ruling and any subsequent IRS
ruling and to the extent such representation or statement relates to future
actions or events under their control, neither CCL nor any member of the CCL
Group will take any action during the Restricted Period that would have caused
such representation or statement to be untrue if CCL had planned or intended to
take such action at the time such representation or statement was made by or on
behalf of CCL.

                  (b) CCL hereby represents and warrants to CPS that CCL has no
present intention to undertake any of the transactions set forth in Section 1.02
(a) (iii) or to cease to engage in the active conduct of the trade or business
(within the meaning of Section 355(b)(2) of the Code) of providing clinical
laboratory testing services.

                  SECTION 1.02. Covenants. (a) CCL covenants and agrees with CPS
that during the Restricted Period:

                  (i) CCL will continue to engage in the clinical laboratory
testing business in the U.S. and will continue to maintain in the U.S. a
substantial portion of its assets and business operations as they existed prior
to the Distributions, provided that the foregoing shall not be deemed to
prohibit CCL from entering into or acquiring other businesses or operations
which may or may not be consistent with its business and operations as they
existed prior to the Distributions so long as CCL continues to engage in such
clinical business in the U.S. and continues to so maintain such substantial
portion in the U.S.;

                  (ii) CCL will continue to manage and to own (A) directly
assets which represent at least fifty percent (50%) of the Gross Assets which
CCL managed and owned directly immediately after the Distributions, and (B)
directly or indirectly through one or more entities, assets which represent at
least 50% of the Gross Assets which CCL owned indirectly through one or more
entities immediately after the Distributions;

                  (iii) except as provided in Section 1.02(c), neither CCL, nor
any of its Affiliates nor any of their respective, directors, officers or other
representatives will undertake, authorize, approve, recommend, permit,
facilitate, or enter into any contract, or consummate any transaction with
respect to: (A) the issuance of CCL Common Stock (including options, warrants,
rights or securities exercisable for, or convertible into, CCL Common Stock) in
a single transaction or in a series of related or unrelated transactions or
otherwise or in the aggregate which would exceed (or could exceed if any such
options, warrants or rights were exercised or such securities were converted)
fifty percent (50%) when expressed as a percentage of the outstanding shares of
CCL Common Stock immediately following the Distributions; (B) the issuance of
any class or series of capital stock or any other instrument (other than CCL
Common Stock and options, warrants, rights or securities exercisable for, or
convertible into, CCL Common Stock) that would constitute equity for federal tax
purposes (such classes or series of capital stock and other instruments being
referred to herein as

                                       2

<PAGE>

"Disqualified CCL Stock"); (C) the issuance of any options, rights, warrants,
securities or similar arrangements exercisable for, or convertible into,
Disqualified CCL Stock; (D) any redemptions, repurchases or other acquisitions
of capital stock or other equity interests in CCL in a single transaction or a
series of related or unrelated transactions, unless such redemptions,
repurchases or other acquisitions (1) satisfy the following requirements: (a)
there is a "sufficient business purpose" (within the meaning of Section
4.05(1)(b) of Revenue Procedure 96-30) for the transaction, (b) the stock to be
purchased, redeemed or otherwise acquired is widely held, (c) the stock
purchases or other acquisitions will be made on the open market, and (d) the
amount of stock purchases, redemption, or other acquisitions in a single
transaction or in a series of related or unrelated transactions will not exceed
an amount of stock representing twenty percent (20%) of the outstanding stock of
CCL immediately following the Distributions; or (2) are made in connection with
employee equity compensation plans of CCL and do not result, individually or in
the aggregate, in the acquisition of more than ten percent (10%) of the voting
power in respect of the outstanding stock of CCL immediately following the
Distributions, (E) the dissolution, merger , or complete or partial liquidation
of CCL or any announcement of such action; or (F) the waiver, amendment,
termination or modification of any provision of the CCL Rights Plan in
connection with, or in order to permit or facilitate, any acquisition or
proposed acquisition of Beneficial Ownership of capital stock or other equity
interest in CCL.

                  (b) Following the six-month anniversary of the Distribution
Date, CCL and its Affiliates may take any action or engage in conduct otherwise
prohibited by Section 1.02 so long as prior to such action or conduct, as the
case may be, Corning or CCL receives (A) a ruling from the IRS in form and
substance reasonably satisfactory to Corning to the effect that the proposed
action or conduct, as the case may be, will not cause the CPS Distribution or
the Other Transactions to fail to qualify for the tax treatment stated in the
IRS Ruling or otherwise to be taxable for federal income tax purposes, or (B) an
Opinion of Counsel in form and substance reasonably satisfactory to Corning to
the effect that the proposed action or conduct, as the case may be, will not
cause the CPS Distribution or the Other Transactions to fail to qualify for the
tax treatment stated in the IRS Ruling or otherwise to be taxable for federal
income tax purposes.

                      ARTICLE 2: CCL Indemnity Obligations

                  SECTION 2.01. Tax Indemnities. (a) If CCL, or another member
of the CCL Group (collectively the "Indemnifying Party") shall take any action
prohibited by Article 1 or shall violate a representation or covenant contained
in Article 1, and the CPS Distribution or any of the Other Transactions shall
fail to qualify for the tax treatment stated in the IRS Ruling primarily as a
result of such action or violation, then the Indemnifying Party shall (jointly
or severally) indemnify and hold harmless CPS and each member of the CPS Group
(collectively the "Indemnified Party") against any and all Taxes imposed upon or
incurred by the Indemnified Party as a result of the failure, including, without
limitation, any liability of the

                                       3

<PAGE>

Indemnified Party arising from Taxes imposed on shareholders of CPS to the
extent any shareholder or shareholders of CPS successfully seek recourse against
the Indemnified Party on account of any such failure, or any liability for such
Taxes which the Indemnified Party may assume or otherwise provide for.

                  (b) Notwithstanding anything to the contrary set forth in this
Agreement, if, during the Restricted Period, any Person or Group of Affiliated
Persons or Associated Persons acquires Beneficial Ownership of twenty percent
(20%) or more of CCL Common Stock (or any other class of outstanding CCL stock)
or commences a tender or other purchase offer for the capital stock of CCL upon
consummation of which such Person or Group of Affiliated Persons or Associated
Persons would acquire Beneficial Ownership of twenty percent (20%) or more of
the CCL Common Stock (or any other class of outstanding CCL stock) and the CPS
Distribution or any of the Other Transactions shall fail to qualify for the tax
treatment stated in the IRS Ruling primarily as a result of such acquisition or
tender or other purchase offer; then the Indemnifying Party shall indemnify and
hold harmless the Indemnified Party against any and all Taxes imposed upon or
incurred by the Indemnified Party and/or its shareholders as a result of the
failure of either Distribution or the Other Transactions to so qualify.

         (c) The Indemnified Party shall be indemnified and held harmless under
Section 2.01(a) without regard to the fact that the Indemnified Party may have
received a supplemental ruling from the IRS or an Opinion of Counsel as
contemplated by Section 1.02(c). The Indemnified Party shall be indemnified and
held harmless under Section 2.01(b) without regard to whether an acquisition of
Beneficial Ownership results from a transaction which is not prohibited under
Article 1.

                   ARTICLE 3: Calculation of Indemnity Amounts

                  SECTION 3.01. Amount of Indemnified Liability. The amount
indemnified against under Article 2 ("Indemnified Liability") for a tax based on
or determined with reference to income shall be deemed to be the amount of the
tax computed by multiplying (i) the taxing jurisdiction's highest marginal tax
rate applicable to taxable income of corporations such as the Indemnified Party
on income of the character subject to tax and indemnified against under Article
2 for the taxable period in which the Distributions occur, times (ii) the gain
or income of the Indemnified Party which is subject to tax in the taxing
jurisdiction and indemnified against under Article 2. In the case of an
Indemnified Liability attributable to a payment owed to a shareholder or
shareholders of CPS, the amount of the Indemnified Liability shall be equal to
the amount so owed, including without limitation, interest, costs, additions,
expenses and penalties. All amounts payable under this Agreement shall be paid
on an after-tax basis. If an Indemnified Liability is of a type that constitutes
a deduction from income in any taxable period in determining the Indemnified
Party's liability for a tax based upon or determined with reference to income,
the amount of the Indemnified Liability shall be reduced by the reduction in the
tax liability of the Indemnified Party.

                                       4

<PAGE>

                         ARTICLE 4: Procedural Matters

                  SECTION 4.01. General. (a) If either the Indemnified Party or
the Indemnifying Party receives any written notice of deficiency, claim or
adjustment or any other written communication from a taxing authority that may
result in an Indemnified Liability, the party receiving such notice or
communication shall promptly give written notice thereof to the other party,
provided that any delay by the Indemnified Party in so notifying an Indemnifying
Party shall not relieve the Indemnifying Party of any liability hereunder,
except to the extent (i) such delay restricts the ability of the Indemnifying
Party to contest the resulting Indemnified Liability administratively or in the
courts in accordance with Section 4.02 and (ii) the Indemnifying Party is
materially and adversely prejudiced by such delay.

                  (b) The parties hereto undertake and agree that from and after
such time as they obtain knowledge that any representative of a taxing authority
has begun to investigate or inquire into either Distribution or any of the Other
Transactions (whether or not such investigation or inquiry is a formal or
informal investigation or inquiry), the party obtaining such knowledge shall (i)
notify the other party thereof, provided that any delay by the Indemnified Party
in so notifying the Indemnifying Party shall not relieve the Indemnifying Party
of any liability hereunder (except to the extent (A) such delay restricts the
ability of the Indemnifying Party to contest the resulting Indemnified Liability
administratively or in the courts in accordance with Section 4.02 and (B) the
Indemnifying Party is materially and adversely prejudiced by such delay), (ii)
consult with the other party from time to time as to the conduct of such
investigation or inquiry, (iii) provide the other party with copies of all
correspondence with such taxing authority or any representative thereof
pertaining to such investigation or inquiry, and (iv) arrange for a
representative of the other party to be present at all meetings with such taxing
authority or any representative thereof pertaining to such investigation or
inquiry.

                  SECTION 4.02. Contests. (a) Provided that (i) the Indemnifying
Party shall furnish the Indemnified Party with evidence reasonably satisfactory
to the Indemnified Party of its ability to pay the full amount of the
Indemnified Liability and (ii) the Indemnifying Party acknowledges in writing
that the asserted liability is an Indemnified Liability, the Indemnifying Party
shall assume and direct the defense or settlement of any hearing, arbitration,
suit or other proceeding (each a "Proceeding") commenced, filed or otherwise
initiated or convened to investigate or resolve the existence and extent of such
liability.

                  (b) If the Indemnified Liability is grouped with other
unrelated asserted liabilities or issues in the Proceeding, the parties shall
use their respective best efforts to cause the Indemnified Liability to be the
subject of a separate proceeding. If such severance is not possible, the
Indemnifying Party shall assume and direct and be responsible only for the
matters relating to the Indemnified Liability.

                                       5

<PAGE>

                  (c) If at any time during a Proceeding controlled by the
Indemnifying Party pursuant to Section 4.02(a) the Indemnifying Party fails to
provide evidence reasonably satisfactory to the Indemnified Party of its ability
to pay the full amount of the Indemnified Liability or the Indemnified Party
reasonably determines, after due investigation, that the Indemnifying Party
could not pay the full amount of the Indemnified Liability, then the Indemnified
Party may assume control of the Proceedings upon seven (7) days written notice.

                  (d) The Indemnifying Party shall pay all out-of-pocket
expenses and other costs related to the Indemnified Liability, including but not
limited to fees for attorneys, accountants, expert witnesses or other
consultants retained by the Indemnifying Party and/or the Indemnified Party,
other than fees for attorneys, accountants, expert witnesses or other
consultants retained solely by the Indemnified Party and incurred at any time
during which the Indemnifying Party is controlling and directing the Proceeding
in respect of which such fees are incurred. To the extent that any such expenses
and other costs have been or are paid by an Indemnified Party, the Indemnifying
Party shall promptly reimburse the Indemnified Party therefor.

                  (e) The Indemnifying Party shall not pay (unless otherwise
required by a proper notice of levy and after prompt notification to the
Indemnified Party of receipt of notice and demand for payment), settle,
compromise or conceded any portion of the Indemnified Liability without the
written consent of the Indemnified Party, which consent shall not be
unreasonably withheld. The Indemnifying Party shall, on a timely basis, keep the
Indemnified Party informed of all developments in the Proceeding and provide the
Indemnified Party with copies of all pleadings, briefs, orders, and other
written papers.

                  (f) Any Proceeding which is not controlled or which is no
longer controlled by the Indemnifying Party pursuant to Section 4.02 shall be
controlled and directed exclusively by the Indemnified Party, and any related
out-of-pocket expenses and other costs incurred by the Indemnified Party,
including but not limited to, fees for attorneys, accountants, expert witnesses
or other consultants, shall be reimbursed by the Indemnifying Party. The
Indemnified Party will not be required to pursue the claim in the federal
district court, Court of Claims or any state court if as a prerequisite to such
Court's jurisdiction, the Indemnified Party is required to pay the asserted
liability unless the funds necessary to invoke such jurisdiction are provided by
the Indemnifying Party.

                  SECTION 4.03. Time and Manner of Payment. The Indemnifying
Party shall pay to the Indemnified Party the amount of the Indemnified Liability
and any expenses or other costs indemnified against (less any amount paid
directly by the Indemnifying Party to the taxing authority) no less than (7)
business days prior to the date payment of the Indemnified Liability is to be
made by any party to the taxing authority. Such payment shall be paid by wire
transfer of immediately available funds to an account designated by the
Indemnified Party by written notice to the Indemnifying Party prior to the due
date of such payment. If the Indemnifying Party delays making payment beyond the
due date hereunder, such party shall

                                       6

<PAGE>

pay interest on the amount unpaid at the IRS Penalty Rate for each day and the
actual number of days for which any amount due hereunder is unpaid.

                  SECTION 4.04. Refunds. In connection with this Agreement,
should an Indemnified Party receive a refund in respect of amounts paid by an
Indemnifying Party to any taxing authority on its behalf, or should any such
amounts that would otherwise be refundable to the Indemnifying Party be applied
by the taxing authority to obligations of the Indemnified Party unrelated to an
Indemnified Liability, then such Indemnified Party shall, promptly following
receipt (or notification of credit), remit such refund and any related interest
to the Indemnifying Party.

                  SECTION 4.05. Cooperation. The parties shall cooperate with
one another in a timely manner in any administrative or judicial proceeding
involving any matter that may result in an Indemnified Liability.

                          ARTICLE 5: General Provisions

                  SECTION 5.01. Notices. All notices, requests, claims and other
communications hereunder shall be in writing and shall be given or made (and
shall be deemed to have been duly given or made upon receipt) by delivery in
person, by courier service, by cable, by telecopy, by telegram, by telex or by
registered or certified mail (postage prepaid, return receipt requested) to the
respective parties at the addresses (or at such other address for a party as
shall be specified in a notice given in accordance with this Section 5.01)
listed below:

                  To CPS:
                           210 Carnegie Center
                           Princeton, New Jersey  08540
                           Telecopy:
                           Attn: General Counsel

                  To CCL:
                           One Malcolm Avenue
                           Teterboro, New Jersey 07608-1070210
                           Telecopy:
                           Attn: General Counsel

                  SECTION 5.02. Miscellaneous. This Agreement, including the
attachments, shall constitute the entire agreement between the parties hereto
with respect to the subject matter hereof and shall supersede all prior
agreements and undertakings, both written and oral, between the parties with
respect to the subject matter hereof and thereof. This Agreement may be executed
in one or more counterparts, and by the different parties hereto in separate
counterparts, each of which when executed shall be deemed to be an original but
all of which

                                       7

<PAGE>

taken together shall constitute one and the same agreement. This Agreement may
not be amended or modified except (a) by an instrument in writing signed by, or
on behalf of, the parties or (b) by a waiver in accordance with Section 5.03.
This Agreement shall be binding upon and inure solely to the benefit of the
parties hereto and their respective subsidiaries, and nothing herein, express or
implied, is intended to or shall confer upon any third parties any legal or
equitable right, benefit or remedy of any nature whatsoever under or by reason
of this Agreement.

                  SECTION 5.03. Waiver. The parties to this Agreement may (a)
extend the time for the performance of any of the obligations or other acts of
the other party or parties, (b) waive any inaccuracies in the representations
and warranties of the other party or parties contained herein or in any document
delivered by the other party or parties pursuant hereto or (c) waive compliance
with any of the agreements or conditions of the other party or parties contained
herein. Any such extension or waiver shall be valid only if set forth in an
instrument in writing signed by the party to be bound thereby. Any waiver of any
term or condition shall not be construed as a waiver of any subsequent breach or
a subsequent waiver of the same term or condition, or a waiver of any other term
or condition, of this Agreement. The failure of any party to assert any of its
rights hereunder shall not constitute a waiver of any such rights.

                  SECTION 5.04. Successors and Assigns. The provisions of this
Agreement shall be binding upon, inure to the benefit of and be enforceable by
the parties and their respective successors and permitted assigns.
Notwithstanding the previous sentence, CCL shall not assign this Agreement or
any rights, interests or obligations hereunder, or delegate performance of any
of its obligations hereunder, without the consent of CPS.

                  SECTION 5.05. Specific Performance. The parties hereto agree
that irreparable damage would occur in the event any provision of this Agreement
was not performed in accordance with the terms hereof and that the parties shall
be entitled to specific performance of the terms hereof, in addition to any
other remedy at law or equity.

                  SECTION 5.06. Governing Law and Severability. This Agreement
shall be governed by, and construed in accordance with, the laws of the State of
New York, applicable to contracts executed in and to be performed entirely
within that state. If any term or other provision of this Agreement is invalid,
illegal or incapable of being enforced by any law or public policy, all other
terms and provisions of this Agreement shall nevertheless remain in full force
and effect so long as the economic or legal substance of the transactions
contemplated hereby is not affected in any manner materially adverse to any
party. Upon such determination that any term or other provision is invalid,
illegal or incapable of being enforced, the parties hereto shall negotiate in
good faith to modify this Agreement so as to effect the original intent of the
parties as closely as possible in an acceptable manner in order that the
transactions contemplated hereby are consummated as originally contemplated to
the greatest extent possible.

                                       8

<PAGE>

         IN WITNESS WHEREOF, the parties have caused this Agreement to be
executed as of the date first written above by their respective officers
thereunto duly authorized.

CORNING PHARMACEUTICAL                      CORNING CLINICAL
   SERVICES                                    LABORATORIES INC.

By__________________________________        By_________________________________
Name:                                         Name:
Title:                                        Title:




                                       9

<PAGE>

                                                        Draft of August 12, 1996

                                     ANNEX A
                                   DEFINITIONS

"Affiliate" shall mean, when used with respect to a specified Person, another
Person that directly, or indirectly through one or more intermediaries, controls
or is controlled by or is under common control with such Person.

"Affiliated Person" shall have the meaning ascribed to such term in the
Investment Company Act of 1940, as amended, and the rules and regulations
promulgated thereunder.

"Associated Person" shall have the meaning ascribed to such term in the
Securities Exchange Act of 1934, as amended, and the rules and regulations
promulgated thereunder.

"Beneficial Ownership" shall have the meaning ascribed to such term in the
Securities Exchange Act of 1934, as amended, and the rules and regulations
promulgated thereunder.

"CCL Common Stock" shall mean the common stock, [$0.50] par value [with attached
Preferred Stock Purchase Rights] of CCL.

"CCL Distribution" shall mean the distribution by Corning to the Corning
shareholders of the CCL Common Stock.

"CCL Group" shall mean the affiliated group of corporations as defined in
Section 1504(a) of the Code of which CCL (or any successor thereto) is the
common parent, excluding CPS and the other members of the CPS Group.

"CCL Rights Plan" shall mean the Preferred Share Purchase Rights Plan of CCL as
governed by the Rights Agreement, dated as of __________, 1996, between CCL and
____________________, as Rights Agent.

"Code" shall mean the Internal Revenue Code of 1986, as amended, and the
Treasury regulations promulgated thereunder, including any comparable successor
legislation.

"Corning Group" shall mean the affiliated group of corporations as defined in
Section 1504(a) of the Code of which Corning (or any successor thereto) is the
common parent, excluding for tax periods of the Corning Group commencing
subsequent to the Distribution Date, CCL and the other members of the CCL Group
and CPS and other members of the CPS Group.

<PAGE>

"CPS Common Stock" shall mean the common stock, [$0.50] par value [with attached
Preferred Stock Purchase Rights] of CPS.

"CPS Distribution" shall mean the distribution by CCL to the CCL shareholders of
the CPS Common Stock.

"CPS Group" shall mean the affiliated group of corporations as defined in
Section 1504(a) of the Code of which CPS (or any successor thereto) is the
common parent.

"CPS Rights Plan" shall mean the Preferred Share Purchase Rights Plan of CPS as
governed by the Rights Agreement, dated as of __________, 1996, between CPS and
____________________, as Rights Agent.

"Distributions" shall mean the each of the CCL Distribution and the CPS
Distribution, including any transfers relating to the CCL Distribution or the
CPS Distribution.

"Distribution Date" shall mean such date as has been or hereafter will be
determined by Corning's Board of Directors as the date as of which the
Distributions shall be effected.

"Gross Assets" shall mean, when used with respect to a specified Person, the
fair market value of such Person's assets unencumbered by any liabilities.

"Group" shall have the meaning ascribed to such term in the Securities Exchange
Act of 1934, as amended, and the rules and regulations promulgated thereunder.

"IRS" shall mean the U.S. Internal Revenue Service.

"IRS Penalty Rate" shall mean the rate of interest imposed from time to time on
underpayments of income tax pursuant to Code section 6621.

"IRS Ruling" shall mean the private letter ruling (together with any
supplements) issued by the IRS in respect of the Ruling Request.

"Opinion of Counsel" shall mean an opinion of independent tax counsel of
recognized national standing and experienced in the issues to be addressed and
otherwise reasonably acceptable to Corning, which sets forth an Unqualified Tax
Opinion in form and substance satisfactory to Corning. In no event shall Corning
be required to conclude that an opinion is satisfactory if there is any risk,
however remote, that the transaction which is the subject of the opinion will
cause either of the Distributions to be taxable to any extent under the Code.

"Other Transactions" shall mean the transactions related to the Distributions
and described in Parts I through IV of the Ruling Request.

                                       2

<PAGE>

"Person" shall mean any natural person, corporation, business trust, joint
venture, association, company, partnership or government, or any agency or
political subdivision thereof.

"Restricted Period" shall mean the two year period following the Distribution
Date.

"Ruling Period" shall mean the period commencing on the Distribution Date and
ending on the later of (i) the third anniversary of the close of the taxable
year of Corning in which the Distributions occur, and (ii) the first anniversary
of the date on which there shall have expired all statutes of limitations in
respect of taxable periods for which Taxes might be imposed or otherwise
assessed in respect of the Distributions and the Other Transactions.

"Ruling Request" shall mean the request for rulings, as amended and
supplemented, under Section 355 of the Code, as filed on behalf of Corning on
June 17, 1996, in respect of the Distributions.

"Taxes" shall mean all federal, state, local and foreign gross or net income,
gross receipts, withholding, franchise, transfer, estimated or other taxes or
similar charges and assessments, including all interest, penalties and additions
imposed with respect to such amounts.

"Unqualified Tax Opinion" shall mean (a) an unqualified "will" opinion of tax
counsel to the effect that a transaction does not disqualify either of the
Distributions from qualifying for tax-free treatment for the shareholders of
Corning and CCL and any member of the Corning Group and the CCL Group under Code
section 355 and any other applicable sections of the Code, assuming that the
Distributions would have qualified for tax-free treatment if such transaction
did not occur. An Unqualified Tax Opinion may rely upon, and assume the accuracy
of, any representations contained in any application for a letter ruling from
the IRS, and any representations contained in an officer's certificate delivered
by an officer of Corning, CCL or CPS to such counsel.

                                       3


                                                        Draft of August 23, 1996

                 CCL/CPS SPIN-OFF TAX INDEMNIFICATION AGREEMENT

                  This SPIN-OFF TAX INDEMNIFICATION AGREEMENT ("Agreement") is
made and entered into this __ day of ______, 1996, by and among CORNING CLINICAL
LABORATORIES INC., a Delaware corporation ("CCL") and CORNING PHARMACEUTICAL
SERVICES INC., a Delaware corporation ("CPS").

                                   WITNESSETH

                  WHEREAS, Corning Incorporated, a New York corporation
("Corning") is the common parent of an affiliated group of corporations within
the meaning of Code1 Section 1504 which includes CPS;

                  WHEREAS, Corning has determined to effect the Distributions
pursuant to a Transaction Agreement (the "Transaction Agreement") dated of even
date herewith;

                  WHEREAS, the IRS has issued the IRS Ruling which states the
tax treatment of the Distributions and the Other Transactions; and

                  WHEREAS, the parties hereto are entering into this Agreement
to indemnify CCL as hereinafter provided in the event the Distributions or the
Other Transactions fail to qualify for the tax treatment stated in the IRS
Ruling due to actions by CPS.

                  NOW, THEREFORE, in consideration of the mutual agreements,
provisions and covenants contained in this Agreement, the parties hereby agree
as follows:

                    ARTICLE 1: Representations and Covenants

                  SECTION 1.01. Representations. (a) CPS has reviewed the
materials submitted to the IRS in connection with the IRS Ruling and, to the
best of CPS's knowledge, these materials, including, without limitation, any
statements and representations concerning CPS, its business, operations capital
structure and/or organization, are complete and accurate in all material
respects. CPS shall, and shall cause each member of the CPS Group, to comply
with each such representation and statement concerning CPS and the CPS Group
made in the materials so submitted, the IRS Ruling and any subsequent IRS
ruling, including without limitation, statements as to the creation, funding and
operation of employee compensation

- --------

1 Capitalized terms not defined herein have the meaning given to them in Annex
A.

<PAGE>

plans by CPS. With respect to any representation or statement made by or on
behalf of CPS in connection with the IRS Ruling and any subsequent IRS ruling
and to the extent such representation or statement relates to future actions or
events under their control, neither CPS nor any member of the CPS Group will
take any action during the Restricted Period that would have caused such
representation or statement to be untrue if CPS had planned or intended to take
such action at the time such representation or statement was made by or on
behalf of CPS.

                  (b) CPS hereby represents and warrants to CCL that CPS has no
present intention to undertake any of the transactions set forth in Section 1.02
(a) (iii) or to cease to engage in the active conduct of the trade or business
(within the meaning of Section 355(b)(2) of the Code) of providing
pharmaceutical services.

                  SECTION 1.02. Covenants. (a) CPS covenants and agrees with CCL
that during the Restricted Period:

                  (i) CPS will continue to engage in the pharmaceutical services
business in the U.S. and will continue to maintain in the U.S. a substantial
portion of its assets and business operations as they existed prior to the
Distributions, provided that the foregoing shall not be deemed to prohibit CPS
from entering into or acquiring other businesses or operations which may or may
not be consistent with its business and operations as they existed prior to the
Distributions so long as CPS continues to engage in such pharmaceutical services
business in the U.S. and continues to so maintain such substantial portion in
the U.S.;

                  (ii) CPS will continue to manage and to own (A) directly
assets which represent at least fifty percent (50%) of the Gross Assets which
CPS managed and owned directly immediately after the Distributions, and (B)
directly or indirectly through one or more entities, assets which represent at
least 50% of the Gross Assets which CPS owned indirectly through one or more
entities immediately after the Distributions;

                  (iii) except as provided in Section 1.02(c), neither CPS, nor
any of its Affiliates nor any of their respective, directors, officers or other
representatives will undertake, authorize, approve, recommend, permit,
facilitate, or enter into any contract, or consummate any transaction with
respect to: (A) the issuance of CPS Common Stock (including options, warrants,
rights or securities exercisable for, or convertible into, CPS Common Stock) in
a single transaction or in a series of related or unrelated transactions or
otherwise or in the aggregate which would exceed (or could exceed if any such
options, warrants or rights were exercised or such securities were converted)
fifty percent (50%) when expressed as a percentage of the outstanding shares of
CPS Common Stock immediately following the Distributions; (B) the issuance of
any class or series of capital stock or any other instrument (other than CPS
Common Stock and options, warrants, rights or securities exercisable for, or
convertible into, CPS Common Stock) that would constitute equity for federal tax
purposes (such classes or series of capital stock and other instruments being
referred to herein as

                                       2

<PAGE>

"Disqualified CPS Stock"); (C) the issuance of any options, rights, warrants,
securities or similar arrangements exercisable for, or convertible into,
Disqualified CPS Stock; (D) any redemptions, repurchases or other acquisitions
of capital stock or other equity interests in CPS in a single transaction or a
series of related or unrelated transactions, unless such redemptions,
repurchases or other acquisitions (1) satisfy the following requirements: (a)
there is a "sufficient business purpose" (within the meaning of Section
4.05(1)(b) of Revenue Procedure 96-30) for the transaction, (b) the stock to be
purchased, redeemed or otherwise acquired is widely held, (c) the stock
purchases or other acquisitions will be made on the open market, and (d) the
amount of stock purchases, redemption, or other acquisitions in a single
transaction or in a series of related or unrelated transactions will not exceed
an amount of stock representing twenty percent (20%) of the outstanding stock of
CPS immediately following the Distributions; or (2) are made in connection with
employee equity compensation plans of CPS and do not result, individually or in
the aggregate, in the acquisition of more than ten percent (10%) of the voting
power in respect of the outstanding stock of CPS immediately following the
Distributions, (E) the dissolution, merger , or complete or partial liquidation
of CPS or any announcement of such action; or (F) the waiver, amendment,
termination or modification of any provision of the CPS Rights Plan in
connection with, or in order to permit or facilitate, any acquisition or
proposed acquisition of Beneficial Ownership of capital stock or other equity
interest in CPS.

                  (b) In addition to the other representations, warranties,
covenants and agreements set forth in this Agreement, CPS and the CPS Group will
take, or refrain from taking, as the case may be, such actions as CCL may
reasonably request during the Ruling Period as necessary to insure that the
Distributions and the Other Transactions qualify for the tax treatment stated in
the IRS Ruling, including, without limitation, such actions as CCL determines
may be necessary to obtain and preserve the IRS Ruling or any subsequent IRS
ruling on which the parties can rely. Without limiting the generality of the
foregoing, CPS and the CPS Group shall cooperate with CCL if CCL determines to
obtain additional IRS rulings pertaining to whether any actual or proposed
change in facts and circumstances affects the tax status of the Distributions or
the Other Transactions.

                  (c) Following the six-month anniversary of the Distribution
Date, CPS and its Affiliates may take any action or engage in conduct otherwise
prohibited by Section 1.02 so long as prior to such action or conduct, as the
case may be, CCL or CPS receives (A) a ruling from the IRS in form and substance
reasonably satisfactory to CCL and upon which CCL can rely to the effect that
the proposed action or conduct, as the case may be, will not cause the
Distributions or the Other Transactions to fail to qualify for the tax treatment
stated in the IRS Ruling or otherwise to be taxable for federal income tax
purposes, or (B) an Opinion of Counsel in form and substance reasonably
satisfactory to CCL and upon which CCL can rely to the effect that the proposed
action or conduct, as the case may be, will not cause the Distributions or the
Other Transactions to fail to qualify for the tax treatment stated in the IRS
Ruling or otherwise to be taxable for federal income tax purposes.

                                       3

<PAGE>

                      ARTICLE 2: CPS Indemnity Obligations

                  SECTION 2.01. Tax Indemnities. (a) If CPS, or another member
of the CPS Group (collectively the "Indemnifying Party") shall take any action
prohibited by Article 1 or shall violate a representation or covenant contained
in Article 1, and either of the Distributions or any of the Other Transactions
shall fail to qualify for the tax treatment stated in the IRS Ruling primarily
as a result of such action or violation, then the Indemnifying Party shall
(jointly or severally) indemnify and hold harmless CCL and each member of the
CCL Group (collectively the "Indemnified Party") against any and all Taxes
imposed upon or incurred by the Indemnified Party as a result of the failure,
including, without limitation, any liability of the Indemnified Party arising
from Taxes imposed on shareholders of CCL to the extent any shareholder or
shareholders of CCL successfully seek recourse against the Indemnified Party on
account of any such failure, or any liability for such Taxes which the
Indemnified Party may assume or otherwise provide for.

                  (b) Notwithstanding anything to the contrary set forth in this
Agreement, if, during the Restricted Period, any Person or Group of Affiliated
Persons or Associated Persons acquires Beneficial Ownership of twenty percent
(20%) or more of CPS Common Stock (or any other class of outstanding CPS stock)
or commences a tender or other purchase offer for the capital stock of CPS upon
consummation of which such Person or Group of Affiliated Persons or Associated
Persons would acquire Beneficial Ownership of twenty percent (20%) or more of
the CPS Common Stock (or any other class of outstanding CPS stock) and either of
the Distributions or any of the Other Transactions shall fail to qualify for the
tax treatment stated in the IRS Ruling primarily as a result of such acquisition
or tender or other purchase offer; then the Indemnifying Party shall indemnify
and hold harmless the Indemnified Party against any and all Taxes imposed upon
or incurred by the Indemnified Party and/or its shareholders as a result of the
failure of either Distribution or the Other Transactions to so qualify.

                (c) The Indemnified Party shall be indemnified and held harmless
under Section 2.01(a) without regard to the fact that the Indemnified Party may
have received a supplemental ruling from the IRS or an Opinion of Counsel as
contemplated by Section 1.02(c). The Indemnified Party shall be indemnified and
held harmless under Section 2.01(b) without regard to whether an acquisition of
Beneficial Ownership results from a transaction which is not prohibited under
Article 1.

                                       4

<PAGE>

                   ARTICLE 3: Calculation of Indemnity Amounts

                  SECTION 3.01. Amount of Indemnified Liability. The amount
indemnified against under Article 2 ("Indemnified Liability") for a tax based on
or determined with reference to income shall be deemed to be the amount of the
tax computed by multiplying (i) the taxing jurisdiction's highest marginal tax
rate applicable to taxable income of corporations such as the Indemnified Party
on income of the character subject to tax and indemnified against under Article
2 for the taxable period in which the Distributions occur, times (ii) the gain
or income of the Indemnified Party which is subject to tax in the taxing
jurisdiction and indemnified against under Article 2. In the case of an
Indemnified Liability attributable to a payment owed to a shareholder or
shareholders of CCL, the amount of the Indemnified Liability shall be equal to
the amount so owed, including without limitation, interest, costs, additions,
expenses and penalties. All amounts payable under this Agreement shall be paid
on an after-tax basis. If an Indemnified Liability is of a type that constitutes
a deduction from income in any taxable period in determining the Indemnified
Party's liability for a tax based upon or determined with reference to income,
the amount of the Indemnified Liability shall be reduced by the reduction in the
tax liability of the Indemnified Party.

                          ARTICLE 4: Procedural Matters

                  SECTION 4.01. General. (a) If either the Indemnified Party or
the Indemnifying Party receives any written notice of deficiency, claim or
adjustment or any other written communication from a taxing authority that may
result in an Indemnified Liability, the party receiving such notice or
communication shall promptly give written notice thereof to the other party,
provided that any delay by the Indemnified Party in so notifying an Indemnifying
Party shall not relieve the Indemnifying Party of any liability hereunder,
except to the extent (i) such delay restricts the ability of the Indemnifying
Party to contest the resulting Indemnified Liability administratively or in the
courts in accordance with Section 4.02 and (ii) the Indemnifying Party is
materially and adversely prejudiced by such delay.

                  (b) The parties hereto undertake and agree that from and after
such time as they obtain knowledge that any representative of a taxing authority
has begun to investigate or inquire into either Distribution or any of the Other
Transactions (whether or not such investigation or inquiry is a formal or
informal investigation or inquiry), the party obtaining such knowledge shall (i)
notify the other party thereof, provided that any delay by the Indemnified Party
in so notifying the Indemnifying Party shall not relieve the Indemnifying Party
of any liability hereunder (except to the extent (A) such delay restricts the
ability of the Indemnifying Party to contest the resulting Indemnified Liability
administratively or in the courts in accordance with Section 4.02 and (B) the
Indemnifying Party is materially and adversely prejudiced by such delay), (ii)
consult with the other party from time to time as to the conduct of such
investigation or inquiry, (iii) provide the other party with copies of all
correspondence with such taxing authority or any representative thereof
pertaining to such investigation or inquiry, and (iv) arrange for a
representative of the other party to be present at

                                       5

<PAGE>

all meetings with such taxing authority or any representative thereof pertaining
to such investigation or inquiry.

                  SECTION 4.02. Contests. (a) Provided that (i) the Indemnifying
Party shall furnish the Indemnified Party with evidence reasonably satisfactory
to the Indemnified Party of its ability to pay the full amount of the
Indemnified Liability and (ii) the Indemnifying Party acknowledges in writing
that the asserted liability is an Indemnified Liability, the Indemnifying Party
shall assume and direct the defense or settlement of any hearing, arbitration,
suit or other proceeding (each a "Proceeding") commenced, filed or otherwise
initiated or convened to investigate or resolve the existence and extent of such
liability.

                  (b) If the Indemnified Liability is grouped with other
unrelated asserted liabilities or issues in the Proceeding, the parties shall
use their respective best efforts to cause the Indemnified Liability to be the
subject of a separate proceeding. If such severance is not possible, the
Indemnifying Party shall assume and direct and be responsible only for the
matters relating to the Indemnified Liability.

                  (c) If at any time during a Proceeding controlled by the
Indemnifying Party pursuant to Section 4.02(a) the Indemnifying Party fails to
provide evidence reasonably satisfactory to the Indemnified Party of its ability
to pay the full amount of the Indemnified Liability or the Indemnified Party
reasonably determines, after due investigation, that the Indemnifying Party
could not pay the full amount of the Indemnified Liability, then the Indemnified
Party may assume control of the Proceedings upon seven (7) days written notice.

                  (d) The Indemnifying Party shall pay all out-of-pocket
expenses and other costs related to the Indemnified Liability, including but not
limited to fees for attorneys, accountants, expert witnesses or other
consultants retained by the Indemnifying Party and/or the Indemnified Party,
other than fees for attorneys, accountants, expert witnesses or other
consultants retained solely by the Indemnified Party and incurred at any time
during which the Indemnifying Party is controlling and directing the Proceeding
in respect of which such fees are incurred. To the extent that any such expenses
and other costs have been or are paid by an Indemnified Party, the Indemnifying
Party shall promptly reimburse the Indemnified Party therefor.

                  (e) The Indemnifying Party shall not pay (unless otherwise
required by a proper notice of levy and after prompt notification to the
Indemnified Party of receipt of notice and demand for payment), settle,
compromise or conceded any portion of the Indemnified Liability without the
written consent of the Indemnified Party, which consent shall not be
unreasonably withheld. The Indemnifying Party shall, on a timely basis, keep the
Indemnified Party informed of all developments in the Proceeding and provide the
Indemnified Party with copies of all pleadings, briefs, orders, and other
written papers.

                                       6

<PAGE>

                  (f) Any Proceeding which is not controlled or which is no
longer controlled by the Indemnifying Party pursuant to Section 4.02 shall be
controlled and directed exclusively by the Indemnified Party, and any related
out-of-pocket expenses and other costs incurred by the Indemnified Party,
including but not limited to, fees for attorneys, accountants, expert witnesses
or other consultants, shall be reimbursed by the Indemnifying Party. The
Indemnified Party will not be required to pursue the claim in the federal
district court, Court of Claims or any state court if as a prerequisite to such
Court's jurisdiction, the Indemnified Party is required to pay the asserted
liability unless the funds necessary to invoke such jurisdiction are provided by
the Indemnifying Party.

                  SECTION 4.03. Time and Manner of Payment. The Indemnifying
Party shall pay to the Indemnified Party the amount of the Indemnified Liability
and any expenses or other costs indemnified against (less any amount paid
directly by the Indemnifying Party to the taxing authority) no less than (7)
business days prior to the date payment of the Indemnified Liability is to be
made by any party to the taxing authority. Such payment shall be paid by wire
transfer of immediately available funds to an account designated by the
Indemnified Party by written notice to the Indemnifying Party prior to the due
date of such payment. If the Indemnifying Party delays making payment beyond the
due date hereunder, such party shall pay interest on the amount unpaid at the
IRS Penalty Rate for each day and the actual number of days for which any amount
due hereunder is unpaid.

                  SECTION 4.04. Refunds. In connection with this Agreement,
should an Indemnified Party receive a refund in respect of amounts paid by an
Indemnifying Party to any taxing authority on its behalf, or should any such
amounts that would otherwise be refundable to the Indemnifying Party be applied
by the taxing authority to obligations of the Indemnified Party unrelated to an
Indemnified Liability, then such Indemnified Party shall, promptly following
receipt (or notification of credit), remit such refund and any related interest
to the Indemnifying Party.

                  SECTION 4.05. Cooperation. The parties shall cooperate with
one another in a timely manner in any administrative or judicial proceeding
involving any matter that may result in an Indemnified Liability.

                         ARTICLE 5: General Provisions

                  SECTION 5.01. Notices. All notices, requests, claims and other
communications hereunder shall be in writing and shall be given or made (and
shall be deemed to have been duly given or made upon receipt) by delivery in
person, by courier service, by cable, by telecopy, by telegram, by telex or by
registered or certified mail (postage prepaid, return receipt requested) to the
respective parties at the addresses (or at such other address for a party as
shall be specified in a notice given in accordance with this Section 5.01)
listed below:

                                       7

<PAGE>

                  To CCL:
                           One Malcolm Avenue
                           Teterboro, New Jersey  07608-1070210
                           Telecopy:
                           Attn: General Counsel

                  To CPS:
                           Carnegie Center
                           Princeton, New Jersey  08540-6233
                           Telecopy:
                           Attn: General Counsel

                  SECTION 5.02. Miscellaneous. This Agreement, including the
attachments, shall constitute the entire agreement between the parties hereto
with respect to the subject matter hereof and shall supersede all prior
agreements and undertakings, both written and oral, between the parties with
respect to the subject matter hereof and thereof. This Agreement may be executed
in one or more counterparts, and by the different parties hereto in separate
counterparts, each of which when executed shall be deemed to be an original but
all of which taken together shall constitute one and the same agreement. This
Agreement may not be amended or modified except (a) by an instrument in writing
signed by, or on behalf of, the parties or (b) by a waiver in accordance with
Section 5.03. This Agreement shall be binding upon and inure solely to the
benefit of the parties hereto and their respective subsidiaries, and nothing
herein, express or implied, is intended to or shall confer upon any third
parties any legal or equitable right, benefit or remedy of any nature whatsoever
under or by reason of this Agreement.

                  SECTION 5.03. Waiver. The parties to this Agreement may (a)
extend the time for the performance of any of the obligations or other acts of
the other party or parties, (b) waive any inaccuracies in the representations
and warranties of the other party or parties contained herein or in any document
delivered by the other party or parties pursuant hereto or (c) waive compliance
with any of the agreements or conditions of the other party or parties contained
herein. Any such extension or waiver shall be valid only if set forth in an
instrument in writing signed by the party to be bound thereby. Any waiver of any
term or condition shall not be construed as a waiver of any subsequent breach or
a subsequent waiver of the same term or condition, or a waiver of any other term
or condition, of this Agreement. The failure of any party to assert any of its
rights hereunder shall not constitute a waiver of any such rights.

                  SECTION 5.04. Successors and Assigns. The provisions of this
Agreement shall be binding upon, inure to the benefit of and be enforceable by
the parties and their respective successors and permitted assigns.
Notwithstanding the previous sentence, CPS shall not assign this Agreement or
any rights, interests or obligations hereunder, or delegate performance of any
of its obligations hereunder, without the consent of CCL.

                                       8

<PAGE>


                  SECTION 5.05. Specific Performance. The parties hereto agree
that irreparable damage would occur in the event any provision of this Agreement
was not performed in accordance with the terms hereof and that the parties shall
be entitled to specific performance of the terms hereof, in addition to any
other remedy at law or equity.

                  SECTION 5.06. Governing Law and Severability. This Agreement
shall be governed by, and construed in accordance with, the laws of the State of
New York, applicable to contracts executed in and to be performed entirely
within that state. If any term or other provision of this Agreement is invalid,
illegal or incapable of being enforced by any law or public policy, all other
terms and provisions of this Agreement shall nevertheless remain in full force
and effect so long as the economic or legal substance of the transactions
contemplated hereby is not affected in any manner materially adverse to any
party. Upon such determination that any term or other provision is invalid,
illegal or incapable of being enforced, the parties hereto shall negotiate in
good faith to modify this Agreement so as to effect the original intent of the
parties as closely as possible in an acceptable manner in order that the
transactions contemplated hereby are consummated as originally contemplated to
the greatest extent possible.

         IN WITNESS WHEREOF, the parties have caused this Agreement to be
executed as of the date first written above by their respective officers
thereunto duly authorized.

CORNING CLINICAL                            CORNING PHARMACEUTICAL
   LABORATORIES INC.                           SERVICES INC.

By__________________________________        By_________________________________
Name:                                         Name:
Title:                                        Title:

<PAGE>

                                                        Draft of August 12, 1996

                                     ANNEX A
                                   DEFINITIONS

"Affiliate" shall mean, when used with respect to a specified Person, another
Person that directly, or indirectly through one or more intermediaries, controls
or is controlled by or is under common control with such Person.

"Affiliated Person" shall have the meaning ascribed to such term in the
Investment Company Act of 1940, as amended, and the rules and regulations
promulgated thereunder.

"Associated Person" shall have the meaning ascribed to such term in the
Securities Exchange Act of 1934, as amended, and the rules and regulations
promulgated thereunder.

"Beneficial Ownership" shall have the meaning ascribed to such term in the
Securities Exchange Act of 1934, as amended, and the rules and regulations
promulgated thereunder.

"CCL Common Stock" shall mean the common stock, [$0.50] par value [with attached
Preferred Stock Purchase Rights] of CCL.

"CCL Distribution" shall mean the distribution by Corning to the Corning
shareholders of the CCL Common Stock.

"CCL Group" shall mean the affiliated group of corporations as defined in
Section 1504(a) of the Code of which CCL (or any successor thereto) is the
common parent, excluding CPS and the other members of the CPS Group.

"CCL Rights Plan" shall mean the Preferred Share Purchase Rights Plan of CCL as
governed by the Rights Agreement, dated as of __________, 1996, between CCL and
____________________, as Rights Agent.

"Code" shall mean the Internal Revenue Code of 1986, as amended, and the
Treasury regulations promulgated thereunder, including any comparable successor
legislation.

"Corning Group" shall mean the affiliated group of corporations as defined in
Section 1504(a) of the Code of which Corning (or any successor thereto) is the
common parent, excluding for tax periods of the Corning Group commencing
subsequent to the Distribution Date, CCL and the other members of the CCL Group
and CPS and other members of the CPS Group.

<PAGE>

"CPS Common Stock" shall mean the common stock, [$0.50] par value [with attached
Preferred Stock Purchase Rights] of CPS.

"CPS Distribution" shall mean the distribution by CCL to the CCL shareholders of
the CPS Common Stock.

"CPS Group" shall mean the affiliated group of corporations as defined in
Section 1504(a) of the Code of which CPS (or any successor thereto) is the
common parent.

"CPS Rights Plan" shall mean the Preferred Share Purchase Rights Plan of CPS as
governed by the Rights Agreement, dated as of __________, 1996, between CPS and
____________________, as Rights Agent.

"Distributions" shall mean the each of the CCL Distribution and the CPS
Distribution, including any transfers relating to the CCL Distribution or the
CPS Distribution.

"Distribution Date" shall mean such date as has been or hereafter will be
determined by Corning's Board of Directors as the date as of which the
Distributions shall be effected.

"Gross Assets" shall mean, when used with respect to a specified Person, the
fair market value of such Person's assets unencumbered by any liabilities.

"Group" shall have the meaning ascribed to such term in the Securities Exchange
Act of 1934, as amended, and the rules and regulations promulgated thereunder.

"IRS" shall mean the U.S. Internal Revenue Service.

"IRS Penalty Rate" shall mean the rate of interest imposed from time to time on
underpayments of income tax pursuant to Code section 6621.

"IRS Ruling" shall mean the private letter ruling (together with any
supplements) issued by the IRS in respect of the Ruling Request.

"Opinion of Counsel" shall mean an opinion of independent tax counsel of
recognized national standing and experienced in the issues to be addressed and
otherwise reasonably acceptable to Corning, which sets forth an Unqualified Tax
Opinion in form and substance satisfactory to Corning. In no event shall Corning
be required to conclude that an opinion is satisfactory if there is any risk,
however remote, that the transaction which is the subject of the opinion will
cause either of the Distributions to be taxable to any extent under the Code.

"Other Transactions" shall mean the transactions related to the Distributions
and described in Parts I through IV of the Ruling Request.

                                       2

<PAGE>

"Person" shall mean any natural person, corporation, business trust, joint
venture, association, company, partnership or government, or any agency or
political subdivision thereof.

"Restricted Period" shall mean the two year period following the Distribution
Date.

"Ruling Period" shall mean the period commencing on the Distribution Date and
ending on the later of (i) the third anniversary of the close of the taxable
year of Corning in which the Distributions occur, and (ii) the first anniversary
of the date on which there shall have expired all statutes of limitations in
respect of taxable periods for which Taxes might be imposed or otherwise
assessed in respect of the Distributions and the Other Transactions.

"Ruling Request" shall mean the request for rulings, as amended and
supplemented, under Section 355 of the Code, as filed on behalf of Corning on
June 17, 1996, in respect of the Distributions.

"Taxes" shall mean all federal, state, local and foreign gross or net income,
gross receipts, withholding, franchise, transfer, estimated or other taxes or
similar charges and assessments, including all interest, penalties and additions
imposed with respect to such amounts.

"Unqualified Tax Opinion" shall mean (a) an unqualified "will" opinion of tax
counsel to the effect that a transaction does not disqualify either of the
Distributions from qualifying for tax-free treatment for the shareholders of
Corning and CCL and any member of the Corning Group and the CCL Group under Code
section 355 and any other applicable sections of the Code, assuming that the
Distributions would have qualified for tax-free treatment if such transaction
did not occur. An Unqualified Tax Opinion may rely upon, and assume the accuracy
of, any representations contained in any application for a letter ruling from
the IRS, and any representations contained in an officer's certificate delivered
by an officer of Corning, CCL or CPS to such counsel.

                                       3


                                  COVANCE INC.
                          EMPLOYEE STOCK PURCHASE PLAN

                  The Covance Inc. Employee Stock Purchase Plan (the "Plan") is
intended to provide the eligible employees of Covance Inc. (the "Company") a
convenient means of purchasing shares of the Company's [Class A] common stock,
par value $.__ per share (the "Stock"). As initially adopted, the Plan is not
intended to qualify as an "employee stock purchase plan" under section 423 of
the Internal Revenue Code of 1986, as amended (the "Code"). The Company may in
the future determine that the Plan should qualify under section 423 of the Code.
At such time, the Company shall re-adopt the Plan as a Code section 423 Plan and
the Plan will then be administered, interpreted and construed in a manner
consistent with the requirements of section 423 of the Code. Specifically,
Article X of the Plan shall not become effective until the Company re-adopts the
Plan as a Code section 423 Plan.

                                    ARTICLE I
                                   DEFINITIONS

         1.1 "Account" means the bookkeeping account established on behalf of
each Participant by the Committee to record payroll deduction contributions made
by such Participant and shares of Stock purchased on his behalf.

         1.2 "Board" means the Board of Directors of the Company.

         1.3 "Business Day" means each day on which the New York Stock Exchange
is open for business.

         1.4 "Compensation" means all regular salary, wages or earnings,
including overtime, commissions and bonuses and amounts that would have been
treated as taxable wages but for their exclusion under Code section 401(k) or
125, but excluding amounts realized from the exercise of qualified or
non-qualified stock options, severance payments and reimbursement of expenses.

         1.5 "Committee" means the committee appointed pursuant to Article VIII
to administer the Plan.

         1.6 "Employee" means any person who is employed by the Company on a
full-time basis or a part-time basis consisting of at least 20 regularly
scheduled hours per week. For the purpose of determining whether an individual
is an Employee, the definition of Company shall also include the Company's
subsidiaries, if any, as defined under Code section 424(f).

         1.7 "Effective Date" means January 1, 1997.

         1.8 "Entry Date" means the first date of any Offering Period.


                                      - 1 -


<PAGE>



         1.9 "Offering Commencement Date" means the first Business Day of each
Offering Period.

         1.10 "Offering Period" means each calendar quarter, or such shorter
period that the Committee may prescribe.

         1.11 "Offering Termination Date" means the last Business Day of each
Offering Period.

         1.12 "Participant" means an Employee who has met the eligibility
requirements of Article II and who has elected to participate pursuant to an
election under Section 3.1.

         1.13 "Plan Year" means the 12-month period ending December 31.

         1.14 "Shares" means shares of Stock that have been allocated to a
Participant's Account.

                                   ARTICLE II
                                   ELIGIBILITY

         2.1 Eligibility. Except as provided in Section 2.2, all individuals who
are Employees shall be eligible to participate in the Plan as of the Entry Date
which coincides with or next follows the date on which the individual became an
Employee.

         2.2 Eligibility Restrictions. An Employee shall not be eligible to
participate in the Plan for any period of time during which he is employed by
the Company or any subsidiary outside of the United States if he is not paid
from the Company's United States payroll during that time.

                                   ARTICLE III
                                  PARTICIPATION

         3.1 Commencement of Participation. An eligible Employee may become a
Participant in the Plan on any Entry Date by completing an enrollment and
payroll deduction form and delivering it to the Company in accordance with
procedures established by the Committee.

         3.2 Payroll Deduction. At the time a Participant files his enrollment
and payroll deduction form, he shall elect to have after-tax deductions made
from his Compensation in an amount stated as a whole percentage of his
Compensation, ranging from one percent (1%) to ten percent (10%).

         3.3 Participants' Accounts. All payroll deductions made from a
Participant's Compensation shall be credited to his Account and used to purchase
shares of Stock in accordance with Article V. Contributions credited to a
Participant's Account shall not accrue interest or earnings during the period
prior to being used to purchase shares of Stock in accordance with Article V.



                                      - 2 -


<PAGE>


         3.4 Changes in Payroll Deductions. The percentage designated by a
Participant as his rate of contribution under Section 3.2 shall automatically
apply to increases and decreases in his Compensation. A Participant may elect to
change the rate of his contributions to any rate permissible under Section 3.2
at any time in accordance with the procedures established by the Committee.

                                   ARTICLE IV
                                    OFFERINGS

         4.1 Offerings. The Plan shall be implemented through offerings of the
Company's Stock made at the beginning of each Offering Period. Each Offering
Period shall begin on the Offering Commencement Date and shall end on the
Offering Termination Date.

         4.2 Purchase Price. The "Purchase Price" per share of Stock with
respect to each Offering Period shall be the lesser of:

                  4.2.1    Eighty-five (85) percent of the mean between the
                           highest and lowest quoted selling prices of the Stock
                           on the New York Stock Exchange (or on such other
                           national securities exchange upon which the Stock may
                           then be listed, hereinafter referred to as the
                           "Exchange") on the Offering Termination Date, or if
                           no sale of Stock occurred on such date, the official
                           closing price on the preceding Business Day; or

                  4.2.2.   Eighty-five (85) percent of the mean between the
                           highest and lowest quoted selling prices of the Stock
                           on the Exchange on the Offering Commencement Date, or
                           if no sale of Stock occurred on such date, the
                           official closing price on the preceding Business Day.

         4.3 Maximum Offering. The maximum number of shares of Stock which shall
be issued under the Plan, subject to adjustment upon changes in capitalization
of the Company as provided in Section 9.3, shall be 1,000,000 shares. If the
total number of shares which would be purchased during any Offering Period
exceeds the maximum number of available shares, the Committee shall make a pro
rata allocation of the available shares in a manner that it determines to be
equitable and the balance of payroll deductions credited to the Accounts of
Participants shall be returned to such Participants as soon as administratively
practicable.

                                    ARTICLE V
                                PURCHASE OF STOCK

         5.1 Automatic Exercise. On each Offering Termination Date, each
Participant shall automatically and without any act on his part be deemed to
have purchased Stock to the full extent of the payroll deductions credited to
his Account during the Offering Period ending on such Offering Termination Date.

         5.2 Fractional Shares. Fractional shares of Stock may be purchased
under the Plan.



                                      - 3 -


<PAGE>



         5.3 Acquisition of Stock. The Company may acquire Stock for use under
the Plan from authorized but unissued shares, treasury shares, in the open
market or in privately negotiated transactions.

         5.4 Accounting for Purchased Stock. All shares of Stock purchased
pursuant to Section 5.1 shall be allocated as Shares to the appropriate
Participant's Account as of the Offering Termination Date on which such shares
are purchased.

                                   ARTICLE VI
                                   ACCOUNTING

         6.1 General. The Committee shall establish procedures to account for
payroll deductions made by a Participant, the number of Shares of Stock
purchased on a Participant's behalf and the number of Shares allocated to a
Participant's Account.

         6.2 Allocation of Stock. Shares of Stock allocated to a Participant's
Account shall be registered in the name of the Company or its nominee for the
benefit of the Participant on whose behalf such shares were purchased.

         6.3 Accounting for Distributions. Shares of Stock distributed or sold
from a Participant's Account shall be debited from his Account on a first-in
first-out basis.

         6.4 Account Statements. Each Participant shall receive at least
quarterly statements of all payroll deductions and shares of Stock allocated to
his Account together with all other transactions affecting his Account.

                                   ARTICLE VII
                          WITHDRAWALS AND DISTRIBUTIONS


         7.1 Withdrawal of Shares. A Participant may elect to withdraw any
number of Shares allocated to his Account by providing notification to the
Company in accordance with procedures established by the Committee. As soon as
administratively practicable following notification of a Participant's election
to withdraw Shares, the Committee shall cause a certificate representing the
number of Shares to be withdrawn to be delivered to the Participant.

         7.2 Distribution Upon Termination. When a Participant terminates his
employment with the Company, any payroll deductions allocated to his Account and
not yet applied to purchase Stock in accordance with Section 5.1 shall be used
to purchase Stock on the next Offering Termination Date that immediately follows
his termination of employment. As soon as administratively practicable following
that Offering Termination Date, a certificate representing all of the
Participant's Shares shall be distributed to him (or his executor, in the event
that he is not alive on the date of distribution).

                                      - 4 -


<PAGE>


                                  ARTICLE VIII
                                 ADMINISTRATION

         8.1 Appointment of Committee. The Board shall appoint a Committee to
administer the Plan, which shall consist of no fewer than three members. The
Board may from time to time appoint members to the Committee in substitution for
or in addition to members previously appointed and may fill vacancies, however
caused, in the Committee.

         8.2 Authority of Committee. The Committee shall have the exclusive
power and authority to administer the Plan, including without limitation the
right and power to interpret the provisions of the Plan and make all
determinations deemed necessary or advisable for the administration of the Plan.
All such actions, interpretations and determinations which are done or made by
the Committee in good faith shall be final, conclusive and binding on the
Company, the Participants and all other parties and shall not subject the
Committee to any liability.

         8.3 Committee Procedures. The Committee may select one of its members
as its Chairman and shall hold its meetings at such times and places as it shall
deem advisable and may hold telephone meetings. A majority of its members shall
constitute a quorum. All determinations of the Committee shall be made by a
majority of its members. Any decision or determination reduced to writing and
signed by a majority of the members of the Committee shall be as fully effective
as if it had been made by a majority vote at a meeting duly called and held. The
Committee may appoint a secretary and shall make such rules and regulations for
the conduct of its business as it shall deem advisable.

         8.4 Expenses. The Company will pay all expenses incident to the
operation of the Plan, including the costs of recordkeeping, accounting fees,
legal fees and the costs of delivery of stock certificates to Participants.

                                   ARTICLE IX
                                  MISCELLANEOUS

         9.1 Transferability. Neither payroll deductions credited to a
Participant's Account nor any rights with regard to the purchase of Stock under
the Plan may be assigned, transferred, pledged or otherwise disposed of in any
way by the Participant other than by will or the laws of descent and
distribution.

         9.2 Status as Owner. Each Participant shall be deemed to legally own
all shares of Stock allocated to his Account and shall be entitled to exercise
all rights associated with ownership of the shares, including, without
limitation, the right to vote such shares in all matters for which Stock is
entitled to vote, receive dividends, if any, and tender such shares in response
to a tender offer.

         9.3 Adjustment Upon Changes in Capitalization. In the event of a
reorganization, recapitalization, stock split, spin-off, split-off, split-up,
stock dividend, combination of shares, merger, consolidation or any other change
in the corporate structure of the Company, or a sale by the Company of all or
part of its assets, the Board may make appropriate adjustments in the number and
kind of

                                      - 5 -
<PAGE>

shares which are subject to purchase under the Plan and in the exercise
price applicable to outstanding options.

         9.4 Amendment and Termination. The Board shall have complete power and
authority to terminate or amend the Plan, including without limitation, the
power and authority to make any amendment that may be deemed to affect the
interests of any Participant adversely. The Plan and all rights of Employees
hereunder shall terminate: (i) at any time, at the discretion of the Board, in
which case any cash balance in Participants' Accounts shall be refunded to such
Participants as soon as administratively possible; or (ii) on the Offering
Termination Date on which Participants become entitled to purchase a number of
shares of Stock that exceeds the maximum number of shares available under the
Plan.

         9.5 No Employment Rights. The Plan does not, directly or indirectly,
create in any Employee any right with respect to continuation of employment by
the Company and it shall not be deemed to interfere in any way with the
Company's right to terminate, or otherwise modify, an Employee's terms of
employment at any time.

         9.6 Withholding. To the extent any payments or distributions under this
Plan are subject to Federal, state or local taxes, the Company is authorized to
withhold all applicable taxes. The Company may satisfy its withholding
obligation by (i) withholding shares of Stock allocated to a Participant's
Account, (ii) deducting cash from a Participant's Account, or (iii) deducting
cash from a Participant's other compensation. A Participant's election to
participate in the Plan authorizes the Company to take any of the actions
described in the preceding sentence.

         9.7 Holding of Funds. The Company shall not be obligated to hold
payroll deductions made under the Plan in trust or to otherwise segregate such
amounts.

         9.8 Choice of Law. Except to the extent superseded by Federal law, the
laws of the State of New Jersey will govern all matters relating to the Plan.


                                    ARTICLE X
                                CODE SECTION 423


         This Article X shall become effective only if the Board adopts a
resolution providing that this Plan is intended to qualify as an "employee stock
purchase plan" under Code section 423. Such resolution shall state the date that
this Section shall become effective.

         10.1 Restrictions on Participation. Notwithstanding any provisions of
the Plan to the contrary, no Employee shall be granted an option to participate
in the Plan under the following conditions:

                  10.1.1              No Employee shall be granted an option if,
                                      immediately after the grant, such Employee
                                      would own stock, and/or hold outstanding
                                      options to purchase stock, possessing 5%
                                      or more of the total combined voting power
                                      or value of all


                                      -6-
<PAGE>

                                      classes of stock of the
                                      Company (for purposes of this paragraph,
                                      the rules of Section 424(d) of the Code
                                      shall apply in determining stock ownership
                                      of any Employee); or

                  10.1.2              No Employee shall be granted an option
                                      which permits his rights to purchase Stock
                                      under the Plan and all other employee
                                      stock purchase plans (as described in
                                      section 423 of the Code) of the Company to
                                      accrue at a rate which exceeds $25,000 of
                                      fair market value of such Stock
                                      (determined at the time such option is
                                      granted) for each calendar year in which
                                      such option is outstanding at any time.
                                      For purposes of this Section 10.1.2:

                                      10.1.2.1 the right to purchase stock under
                                      an option accrues when the option (or any
                                      portion thereof) first becomes exercisable
                                      during the calendar year;

                                      10.1.2.2 the right to purchase stock under
                                      an option accrues at the rate provided in
                                      the option, but in no case may such rate
                                      exceed $25,000 of fair market value of
                                      such stock (determined at the time such
                                      option is granted) for any one calendar
                                      year; and

                                      10.1.2.3 a right to purchase stock which
                                      has accrued under one option granted
                                      pursuant a plan may not be carried over to
                                      any other option.

         10.2 Amendment of Plan. The Board shall not, without the approval of
the shareholders of the Company (i) increase the maximum number of shares which
may be offered under the Plan (except pursuant to Section 9.3); (ii) modify the
requirements as to eligibility for participation in the Plan; or (iii) in any
other way cause the Plan to fail the requirements of section 423 of the Code.

         10.3 Shareholder Approval. The Plan must be approved by a majority of
the shareholders of the Company within 12 months following the date that the
Board re-adopts the Plan as a Plan intended to qualify as an "employee stock
purchase plan" under Code section 423.

                                    * * * * *

               To record the adoption of the Plan, Covance Inc. has caused its
authorized officers to affix its Corporate name and seal this _____ day of
_____________, 1996.


[CORPORATE SEAL]                                     COVANCE INC.




Attest:______________________________    By:___________________________________

                                      - 7 -

                                  COVANCE INC.


                      EMPLOYEE EQUITY PARTICIPATION PROGRAM

<PAGE>

                                  COVANCE INC.
                      EMPLOYEE EQUITY PARTICIPATION PROGRAM


1. Purpose

The Employee Equity Participation Program (the "Program") is intended to
encourage executive, managerial, technical and other employees of (i) Covance
Inc. (the "Corporation"), (ii) any "subsidiary corporation" of the Corporation
within the meaning of Section 424 of the Internal Revenue Code of 1986, as
amended (the "Code") or of any successor section, or (iii) any other entity in
which the Corporation holds beneficially at least one-half of the ownership
interest (such entity or "subsidiary corporation" being referred to herein as a
"Subsidiary") to become owners of stock of the Corporation in order to increase
their proprietary interest in the Corporation's success; to stimulate the
efforts of certain key executive, managerial, technical and other employees by
giving suitable recognition to services which contribute materially to the
Corporation's success; and to provide such employees with additional incentive
and reward opportunity based, in part, upon the attainment of predetermined
goals over specified periods. The Program shall consist of two plans: (a) the
Stock Option Plan and (b) the Incentive Stock Plan.

2. Administration

The Program shall be administered by a committee appointed by the Board of
Directors of the Corporation, to be known as the "Compensation Committee" (the
"Committee"), consisting of not less than three members of the Corporation's
Board of Directors, each member of which shall be a "non-employee director"
within the meaning of Rule 16b-3(d)(1) promulgated under the Securities Exchange
Act of 1934 (the "1934 Act") or any successor thereto and an "outside director"
within the meaning set forth in regulations promulgated under Section 162(m) of
the Code. Without limiting the foregoing, unless and to the extent those
definitions are amended, no member of the Committee shall be an officer or
employee of the Corporation or a subsidiary thereof, a former officer of the
Corporation, a former employee of the Corporation who receives compensation for
prior services (other than benefits under a tax-qualified retirement plan)
during the taxable year or any other person who receives directly or indirectly
in any capacity (other than as a director) remuneration in excess of the lesser
of $60,000 or 5 percent of the gross income realized by the entity employing
such member during such entity's taxable year ending with or within the
Corporation's taxable year or any person who is a member of a law firm retained
by, or a partner or executive officer of an investment banking firm that
performs services for, the Corporation. No member of the Committee shall have
been eligible to participate in the Program in the preceding year nor be
eligible to participate in the Program while serving on the Committee. The
Committee shall select periodically the executive, managerial, technical and
other employees who shall participate in the Program and the extent of their
participation in any particular Plan under the Program and shall report such
selections and levels of participation to the Board of Directors.


                                       1
<PAGE>

The Committee's interpretation and construction of any provisions of this
Program or any Plan or any right, option or award granted or contract executed
under it shall be final unless otherwise determined by the Board of Directors,
which determination shall be final. No member of the Board of Directors or the
Committee shall be liable for any action or determination made in good faith.

3. Eligibility

The Committee shall from time to time select the executive, managerial,
technical and other employees (including officers and employees who are
directors) of the Corporation and of any Subsidiary who shall be eligible to
participate in any Plan under the Program.

4. Stock

The shares subject to options, grants or incentive stock rights under the
Program shall be shares of the Corporation's Common Stock par value $.50 per
share, either authorized but unissued or issued and held in treasury or such
other securities as may be issued by the Corporation in substitution therefor.
The total amount of the Common Stock of the Corporation which may be (i) sold
pursuant to options granted under the Stock Option Plan and (ii) granted, or
issued pursuant to incentive stock rights awarded, under the Incentive Stock
Plan shall not exceed 4,725,000 shares. There may be awarded under the Incentive
Stock Plan in lieu of shares the cash equivalent thereof valued at the date that
the Committee determines whether, or to what extent, performance objectives have
been met. In each case, the number of shares shall be subject to adjustment in
accordance with the provisions of Section 5.

Shares from the unexercised portion of the options which expire or of the
options which are terminated during the period when options may be granted and
shares forfeited or not earned under the Incentive Stock Plan may again either
(i) be the subject of an option under the Stock Option Plan or (ii) be awarded
or be the subject of rights granted under the Incentive Stock Plan. Shares of
the Common Stock of the Corporation used by an optionee as full or partial
payment to the Corporation for the purchase price of shares subject to an option
agreement, the terms of which explicitly provide for the grant of an additional
option as contemplated by Section 6(a)(i) hereof, shall again be made available
for use under the Program. Shares otherwise surrendered upon the exercise of
stock options may not again be the subject of options or awards granted under
the Program. Shares surrendered under the Program in payment of taxes due upon
the exercise of stock options or upon the recognition of income for shares
issued under the Incentive Stock Plan may not be issued again under the Program.

No single eligible employee under the Stock Option Plan may receive grants of
stock options covering in excess of 472,500, or 10% of the total, shares
authorized under the Program.

5. Recapitalization

The number of shares of Common Stock which may be granted, awarded or earned
under the Incentive Stock Plan or made subject to options granted under the
Stock Option Plan in the


                                       2
<PAGE>

aggregate and to any single eligible employee, the number of shares covered by
each outstanding option, and the price per share thereunder, and the number of
shares granted or subject to incentive stock rights under the Incentive Stock
Plan shall all be proportionally adjusted for any increase or decrease in the
number of issued shares of Common Stock of the Corporation resulting from a
subdivision or consolidation of shares or other capital adjustment, the
distribution of shares of capital stock to stockholders of the Corporation, the
payment of a stock dividend or other increase or decrease in such shares
effected without receipt of consideration by the Corporation, or any
distribution or spin-off of assets (other than a normal cash dividend) to the
stockholders of the Corporation.

Subject to any required action by the stockholders, if the Corporation shall be
the surviving corporation in any merger or consolidation, any option granted
under the Stock Option Plan and any incentive stock right granted under the
Incentive Stock Plan shall apply to the securities to which a holder of the
number of shares of Common Stock subject to the option or such right, as the
case may be, would have been entitled before the occurrence of such event. A
dissolution or liquidation of the Corporation, or a merger or consolidation in
which the Corporation is not the surviving corporation, shall cause every option
outstanding under the Stock Option Plan to terminate, except that the surviving
corporation may, in its absolute and uncontrolled discretion, tender an option
or options to purchase its shares on terms and conditions, both as to number of
shares and otherwise, which will substantially preserve the rights and benefits
of any option then outstanding under the Stock Option Plan. Upon the dissolution
or liquidation of the Corporation, or upon the effective date of any merger or
consolidation in which the Corporation is not the survivor and in which the
survivor has not tendered options as provided in the preceding sentence, the
Corporation shall deliver to each optionee whose incentive stock options are
being terminated an amount in cash equal to the difference between the option
price and the fair market value of a share of the Corporation's Common Stock
determined in good faith by the Committee. In the case of such a merger or
consolidation in which the Corporation is not the survivor, the Corporation
shall also deliver to each person whose incentive stock options are being
terminated and to each person who had exercised an incentive stock option and
who was holding the shares so purchased for long-term capital gains treatment an
amount equal to the difference between the federal income tax which the person
would be required to pay as a result of being unable to hold such shares for
long-term capital gains purposes (assuming a sale price equal to the fair market
value as provided above) and the tax such person is required to pay as a result
of having to dispose of shares on account of such merger or consolidation.

In the event of a change in the Corporation's presently authorized Common Stock
which is limited to a change of authorized shares with par value into the same
number of shares with a different par value or into the same number of shares
without par value, the shares resulting from any such change shall be deemed to
be Common Stock within the meaning of the Program.

6. Stock Option Plan

(a)  The Committee may from time to time grant options, including but not
     limited to performance-based stock options and to incentive stock options
     permitted by Section 422 of the Code, to purchase shares of Common Stock,
     evidenced by agreements in such form


                                       3
<PAGE>

     as the Committee may, from time to time, approve, containing in substance
     the following terms and conditions:

     (i)  The option price shall be payable in full upon the exercise of the
          option and may be paid either in United States dollars, or under rules
          established and maintained from time to time by the Committee, in
          shares of the Common Stock of the Corporation owned by the optionee,
          or a combination of cash and shares. Under such rules, an optionee
          paying the purchase price of an option in already-owned, freely
          transferable, unencumbered shares of Common Stock of the Corporation
          may receive new options to purchase shares of Common Stock of the
          Corporation at the then current market price (being the mean between
          the high and low selling prices of the Corporation's Common Stock on
          the New York Stock Exchange on the date of exercise) for the same
          number of shares surrendered upon exercise of the original option. In
          no circumstance will the total number of shares subject to the new
          option granted exceed the number of shares surrendered upon exercise
          of the original option, will the new option be exercisable within
          twelve months of the date of exercise or will the new option have a
          life beyond that of the original option.

          Shares of the Corporation's Common Stock shall be valued at the mean
          between the high and low selling prices of the Corporation's Common
          Stock on the New York Stock Exchange on the date of exercise.

     (ii) The option shall state the total number of shares to which it
          pertains.

    (iii) The option price shall be not less than 100% of the fair market value
          of the shares on the date of the granting of the option.

     (iv) Each option granted under the Stock Option Plan shall expire on the
          date designated by the Committee but in no event more than ten years
          from the date the option is granted.

     (v)  The Committee may in its discretion provide that an option may not be
          exercised in whole or in part for any period or periods of time
          specified by the Committee. Except as may be so provided by the
          Committee and except as otherwise provided herein, any option may be
          exercised in whole at any time or in part from time to time after the
          option has vested in accordance with the terms of the applicable
          agreement and during its term; provided, however, that in no
          circumstance will an option under the Stock Option Plan become
          exercisable in less than twelve months from the date of grant.

     (vi) The aggregate fair market value (determined as of the time the option
          is granted) of the stock for which any employee may be granted
          incentive stock options under this Plan or any other plans of the
          Corporation or any subsidiary of the Corporation shall not exceed
          $100,000 (or such other limit as may be in effect from time to time
          under Section 422 of the Code or any statutory successor thereto) in
          any calendar year in


                                       4
<PAGE>

          which such option or any portion thereof first becomes exercisable
          pursuant to the terms of the agreement between such employee and the
          Corporation.

    (vii) If, in the opinion of counsel for the Corporation, the listing,
          registration or qualification of the shares subject to option under
          any securities exchange or under any state or Federal law, or the
          consent or approval of any governmental regulatory body, or an
          exemption from registration, is necessary or desirable, each option
          shall be subject to the requirement that such option may not be
          exercised in whole or in part unless such listing, registration,
          qualification, consent, approval or exemption shall have been effected
          or obtained free of any conditions not acceptable to the Committee.

    (viii) An optionee shall have no rights as a stockholder with respect to
          shares covered by his option to purchase until the date of the
          issuance or transfer of the shares to him and only after such shares
          are fully paid. No adjustment will be made for dividends or other
          rights for which the record date is prior to the date of such issuance
          or transfer, except as provided in Section 5.

     (ix) The option agreements authorized under the Stock Option Plan shall
          contain such other provisions not inconsistent with this Program as
          the Committee may deem advisable.

(b)  Options may be granted under the Stock Option Plan from time to time in
     substitution for stock options held by consultants to or directors or
     employees of other corporations who are about to become and who do
     concurrently with the grant of such options become consultants to or
     directors or employees of the Corporation or a Subsidiary as the result of
     a merger or consolidation of the employing corporation with the Corporation
     or a Subsidiary, or the acquisition by the Corporation or a Subsidiary of
     the assets of the employing corporation, or the acquisition by the
     Corporation or a Subsidiary of stock of the employing corporation as the
     result of which it becomes a Subsidiary. The terms and conditions of the
     substitute options so granted may vary from the terms and conditions set
     forth in Section 6 of this Program to such extent as the Committee at the
     time of grant may deem appropriate to conform, in whole or in part, to the
     provisions of the stock options in substitution for which they are granted.
     Options granted under this paragraph (b) or pursuant to the terms of the
     agreements contemplated by Section 6(a)(i) hereof shall not reduce the
     shares available for options, grants or incentive stock rights under the
     Program as set forth in Section 4 hereof.

(c)  If the optionee's employment by the Corporation or a Subsidiary shall
     terminate, his option shall terminate unless otherwise determined by the
     Committee, or specific provision has been otherwise made as evidenced by
     the terms of the option agreement approved by the Committee. The Committee
     shall have full power and authority to determine whether, to what extent
     and under what circumstances any option shall be exercisable, suspended or
     canceled in the event of an optionee's termination of employment.


                                       5
<PAGE>

     If an optionee dies while in the employ of the Corporation or a Subsidiary,
     or within three months after termination of employment with options
     exercisable pursuant to action taken by the Committee or otherwise in
     accordance with the preceding sentences, the optionee's estate, personal
     representative or beneficiary shall have the right to exercise such option
     in accordance with the terms of the option agreement with respect to all
     shares subject to option on the date of death.

     If an optionee shall be transferred from the Corporation to a Subsidiary or
     from a Subsidiary to the Corporation or from a Subsidiary to another
     Subsidiary, his employment shall not be deemed to have terminated. If an
     optionee shall be employed by a corporation or an entity which ceases to be
     a Subsidiary, the Committee may, subject to the provisions of clauses (iv)
     and (v) of Paragraph (a) of this Section 6, permit the participant to
     exercise options held for such period of time as it determines with respect
     to all shares which were available for purchase by the optionee on the date
     the corporation or entity ceased to be a Subsidiary.

7. Incentive Stock Plan

The Committee may from time to time award shares of Incentive Stock and grant
incentive stock rights, or either, to eligible employees on the terms set forth
herein.

(a)  "Incentive Stock" shall be shares of the Corporation's Common Stock awarded
     pursuant to the terms of the Incentive Stock Plan.

(b)  An "incentive stock right" shall, subject to the terms, conditions and
     limitations of this Section 7, give the holder thereof the right to receive
     in consideration of services performed for, but without payment of cash to,
     the Corporation such shares of Common Stock, cash or a combination of the
     two as the Committee may determine.

(c)  Subject to the limitations of Section 4, the Committee shall from time to
     time select, and report to the Board of Directors, (i) the individual
     employees who are to receive shares of Incentive Stock or incentive stock
     rights, or a combination thereof, (ii) the number of shares of Incentive
     Stock a designated employee is to receive, either directly or upon
     maturation of an incentive stock right, (iii) whether ownership of, or any
     portion of, such shares of Incentive Stock is to be vested in the
     designated employee without the possibility of forfeiture or other
     restrictions at the time of the Committee's action or at one or more
     specified dates in the future, (iv) whether ownership of such, or any
     portion of such, shares of Incentive Stock is to be vested in the
     designated employee at the time of the Committee's action, but subject to
     the possibility of forfeiture or other restrictions, and (v) the specific
     dates from the date of the Committee's award over which the possibility of
     forfeiture or other restrictions are to lapse.

     Shares of Incentive Stock shall be issued in the name of, and distributed
     to, those employees from time to time designated by the Board as recipients
     of Incentive Stock as follows:


                                       6
<PAGE>

     (1)  Each employee designated as a recipient of shares of Incentive Stock
          shall receive, promptly after the date or dates the Committee
          determines the number of such shares which such employee is to receive
          not subject to the possibility of forfeiture and other restrictions,
          one or more stock certificates registered in the name of the
          designated employee for such number of shares, the ownership of which
          is vested non-forfeitably and without restriction in such employee;
          and

     (2)  Certificates covering shares of Incentive Stock subject to the
          possibility of forfeiture and other restrictions shall be issued
          promptly after the date or dates the Committee determines the number
          of such shares to be issued in the name of the designated employee but
          held by the Corporation as provided in clause (e) below.

(d)  The shares which are granted subject to restrictions and the possibility of
     forfeiture (and all shares issued or distributed by means of dividends,
     splits, combinations, reclassifications, or other capital changes thereon)
     (i) may not be sold, assigned, transferred, pledged or otherwise
     encumbered, except (a) for gifts to a spouse, ancestors, or descendants, or
     to trusts for their benefit and (b) pursuant to the qualified domestic
     relations orders referred to in Section 9 hereof, subject, however, in each
     such case to the restrictions and possibility of forfeiture applicable to
     such shares and (ii) except as otherwise provided in an agreement approved
     by the Committee are to be forfeitable to the Corporation upon termination
     of employment for any reason other than death, disability approved by the
     Corporation or retirement with the consent of the Corporation. The
     restrictions and possibility of forfeiture imposed by this clause (d) shall
     lapse at such time and in such proportions as the Committee shall, subject
     to limitations of clause (c) above, determine.

(e)  Each certificate issued in respect of shares granted under the Incentive
     Stock Plan subject to restrictions on transfer and the possibility of
     forfeiture shall be registered in the name of the employee but shall be
     held by the Corporation in safekeeping for the employee and until such
     restrictions and the possibility of forfeiture shall lapse. Such
     certificates shall bear a legend substantially as follows:

     "The transferability of this certificate and the shares of stock
     represented hereby are restricted and the shares are subject to the further
     terms and conditions (including forfeiture) contained in the Incentive
     Stock Plan of Covance Inc. and an agreement executed pursuant thereto. A
     copy of such Plan and such agreement are on file in the office of the
     Secretary of Covance Inc., Princeton, New Jersey."

(f)  An employee who is to receive shares of Incentive Stock only upon the
     expiration of certain specified periods or who is the holder of an
     incentive stock right shall have no rights as a stockholder with respect to
     any shares which may become vested in, or be awarded to, him, as the case
     may be, until such shares have been actually issued.

(g)  The value of shares of the Incentive Stock or the value of the shares of
     Common Stock granted by the Corporation to the holder of an incentive stock
     right shall be the mean between the high and low selling prices of the
     Corporation's Common Stock on the New


                                       7
<PAGE>

     York Stock Exchange on the date the Committee determines that the
     applicable performance objectives were met or the date the possibility of
     forfeiture shall terminate, as the case may be.

(h)  At the time an incentive stock right is granted, the Committee shall
     establish with respect to each holder one or more performance periods and
     performance objectives. If the objectives have been met and are being
     maintained at the end of the applicable performance period to the
     satisfaction of the Committee, the holder of the incentive stock right
     shall receive promptly the shares and/or cash which are subject to the
     agreement referred to below.

(i)  Any provisions hereof the contrary notwithstanding, the Committee shall
     have the authority and the power to adjust performance periods, performance
     objectives and the number of shares which may be awarded pursuant to an
     incentive stock right if it determines that conditions so warrant. Such
     conditions may include, but need not be limited to, changes in functional
     responsibilities of a holder of an incentive stock right, changes in laws
     or government regulations, changes in accounting treatment or in generally
     accepted accounting principles, acquisitions, dispositions or distributions
     deemed to be material, or extraordinary events which significantly impact
     consolidated financial performance.

(j)  Incentive stock rights shall be evidenced by agreements in such form and
     not inconsistent with the Incentive Stock Plan as the Committee shall
     approve from time to time, which agreements shall, among other things,
     contain in substance the following terms, conditions and provisions:

     (i)  The number of shares to which the incentive stock right relates and
          whether such rights are to be paid in shares, in cash or in a
          combination or the two;

     (ii) The length of the performance period or periods;

    (iii) The performance objectives applicable to an individual granted an
          incentive stock right, which objectives may relate, but shall not be
          limited, to overall corporate performance measures, such as earnings
          per share, return on stockholders' equity and return on capital, or to
          divisional, subsidiary or other business unit performance measures, or
          to a combination of each; and

     (iv) Such other rules, as determined by the Committee, governing the
          continuation of an incentive stock right after the holder terminates,
          either voluntarily or involuntarily, his employment with the
          Corporation.

(k)  Unless otherwise determined by the Committee or set forth in the agreement
     contemplated by subsection (j) above, if the holder of an incentive stock
     right shall cease to be employed by the Corporation or a Subsidiary, his
     incentive stock right shall terminate immediately. However, if employment
     is terminated on account of death, retirement or termination of employment
     with the consent of the Corporation (including termination by reason of
     retirement, disability or a Subsidiary ceasing to be such), the Committee
     may award to such


                                       8
<PAGE>

     employee such shares or cash at such time and under such conditions as it
     shall in its sole discretion determine.

8. Amendment and Administration of the Program

The Board of Directors may, upon the recommendation of the Committee, from time
to time alter, amend, suspend, or discontinue the Program or either Plan
thereunder, except that no alteration or amendment shall, without the approval
of the holders of a majority of the outstanding shares entitled to vote thereon,
increase the total number of shares which may be sold or awarded under the
Program, decrease the price at which options may be granted, change the
standards of eligibility of employees eligible to participate, materially
increase the benefits of the Program or either Plan thereunder to participants,
or extend the term of the Program or of options granted thereunder. Adjustments
in the total number of shares purchasable or awardable under the Program or
optioned to any individual and adjustments of the option price may be made,
however, without stockholder approval pursuant to the adjustment provisions
described under the provisions of Section 5 hereof. No amendment or modification
shall apply to affect adversely any employee with respect to incentive stock or
incentive stock rights already awarded to him or an option already granted.
Anything to the contrary in this Section 8 notwithstanding, should the
provisions of Rule 16b-3, or any successor rule, under the 1934 Act be amended,
the Board may amend the Program in accordance with any modifications to such
Rule.

With respect to persons subject to Section 16 of the 1934 Act, transactions
under the Program are intended to comply with all applicable conditions of Rule
16b-3, or any successor rule, under the 1934 Act. To the extent any provision of
the Program or action by the Committee, the Board of Directors or any
administrator fails to so comply, it shall be deemed null and void, to the
extent permitted by law and deemed advisable by the Committee or the Board of
Directors.

9. Assignability

No option or right granted under the Program shall be assignable or transferable
except by Will, by the laws of descent and distribution, or except for an
incentive stock option pursuant to domestic relations orders as defined in or
meeting the requirements of the Code or Title I of the Employee Retirement
Income Security Act of 1974, as amended. During the lifetime of an optionee, an
option shall be exercisable only by him and any shares purchased upon the
exercise of an option shall be issued in the name of the optionee alone.

10. Effective Date and Term of Program.

The Program shall become effective when approved by a majority of the votes cast
at a meeting of the Corporation's stockholders by stockholders entitled to vote
thereon. No shares may be optioned or awarded (except upon the attainment of
performance goals contemplated by Section 7(h) hereof) and no incentive stock
rights may be granted under the Program after the fifth anniversary, plus 60
calendar days, of the Program's effective date.

11. Use of Proceeds

Proceeds from the sale of stock under the Program shall constitute general funds
of the Corporation.


                                       9
<PAGE>

12. Withholding

Whenever under the Program shares are to be issued in satisfaction of options,
awards or rights granted thereunder, the Corporation shall have the right to
require the employee to remit to it an amount in cash, in shares of the
Corporation's Common Stock, or though the reduction of options, awards or rights
to be issued thereof, necessary to satisfy federal, state and local withholding
tax requirements prior to the delivery of any certificate or certificates for
shares. Whenever under the Program payments are to be made in cash, such payment
shall be net of an amount necessary to satisfy federal, state and local
withholding tax requirements.





                                       10


                                  COVANCE INC.







- --------------------------------------------------------------------------------

                                      RULES
                                     of the
                          COVANCE RESTRICTED SHARE PLAN

- --------------------------------------------------------------------------------






                  Established by the Company in General Meeting
                                     on [ ]


<PAGE>



                                      Rules
                                     of the
                          Covance Restricted Share Plan




                                    CONTENTS

Rule                                                                    Page No.



1.       Definitions......................................................     1

2.       Grant of Awards..................................................   4-6

3.       Conditions relating to the grant of Awards.......................   6-7

4.       Rights of Award Holder during Vesting Period.....................   7-8

5.       Lapse of Awards..................................................     8

6.       Termination of Vesting Period and Lapse of Awards................   8-9

7.       Release of Restricted Shares.....................................     9

8.       Issue of Shares..................................................     9

9.       Discretion As to Form of Payment.................................  9-10

10.      Adjustments......................................................    10

11.      Administration................................................... 10-11

12.      Alterations......................................................    12

13.      General..........................................................    12




<PAGE>



                   Rules of the Covance Restricted Share Plan

1.       Definitions
         -----------

         In this Plan,  the following  words and  expressions  shall,  where the
         context so permits, have the meanings set forth below:

         "the Auditors"             the  auditors  for  the  time  being  of the
                                    Company   acting  as  experts   and  not  as
                                    arbitrators;

         "Award"                    an award of  Restricted  Shares  pursuant to
                                    the Plan;

         "Award Certificate"        a certificate issued under Rule 2.4;

         "Award Holder"             a person to whom an Award  has been  granted
                                    (or, as the context  requires,  his personal
                                    representatives);

         "Base Compensation"        the  annual  rate of salary  of an  Eligible
                                    Employee,  excluding bonuses and benefits in
                                    kind

         "the Company"              Covance Inc. (Covance)

         "Date of Grant"            the date as of  which  an  Award is  granted
                                    under the Plan pursuant to Rule 2;

         "the Directors"            the board of directors of the Company,  or a
                                    duly authorized committee thereof;




<PAGE>



         "Eligible Employee"        any person who is a US Eligible  Employee or
                                    an International Eligible Employee

         "Group"                    the Company and its Subsidiaries and `member
                                    of   the   Group'    shall   be    construed
                                    accordingly;

         International Eligible     any person who is a director  or employee of
          Employee                  an International Participating Company.

         International              a member of the  Group,  which the Board has
          Participating Company     designated to  participate in the Plan as an
                                    International   Participating   Company   --
                                    Appendix   A(1)   lists  the   International
                                    Participating   Companies  at  the  date  of
                                    establishment of the Plan.


         "Market Value"             in  relation  to a  Share  on any day is the
                                    middle  market  quotation  for such Share on
                                    the [New York Stock Exchange];

         "Participating Company"    Any    US    Participating     Company    or
                                    International Participating Company.

         "Restricted Shares"        Shares  which are the  subject  of an extant
                                    Award  under the Plan in  relation  to which
                                    the Vesting Period has not terminated;


                                       2

<PAGE>



         "Rules"                    the  Rules of the Plan and  "Rule"  shall be
                                    construed accordingly;

         "the Plan"                 the  Covance  Restricted  Share  Plan in its
                                    present  form,  or  as  from  time  to  time
                                    altered in accordance with the Rules;

         "Share"                    a share in the Company;

         "Subsidiary"               has the meaning  ascribed by Section 424f of
                                    the US Internal Revenue Code of 1986;

         "the Trustees"             the  trustees  from  time  to  time  of  the
                                    Covance Employee Share Trust;

         "US Eligible Employee"     any person who is a director  or employee of
                                    a  US  Participating   Company  and  who  is
                                    eligible  to  receive a  contribution  under
                                    Section  2.1 of the Covance  Employee  Stock
                                    Ownership   plan  (without   regard  to  the
                                    limitations   imposed   by   Section   4.04,
                                    thereof).

         "US Participating          a member  of the  Group  which the Board has
          Company"                  designated to  participate  in the Plan as a
                                    US  Participating  Company -- Appendix  A(2)
                                    lists the US Participating  Companies at the
                                    date of establishment of the Plan.

         "Vesting Period"           the period of time from the Grant Date until
                                    the date when the restrictions placed on the
                                    Restricted Shares lapse.

                                       3

<PAGE>



         References to any statutory provision are to that provision as amended
         or re-enacted from time to time, and, unless the context otherwise
         requires, words in the singular shall include the plural (and vice
         versa) and words importing the masculine the feminine (and vice versa).

2.       Grant of Awards
         ---------------

         2.1      (a)      Subject  to Rule 2.2,  the  Directors  may,  at their
                           absolute  discretion,  grant Awards under the Plan to
                           Eligible Employees.

                  (b)      The Directors may adopt such  procedure as they think
                           fit for granting  Awards,  whether by  invitation  to
                           Eligible Employees to apply for Awards or by granting
                           Awards without issuing invitations.

         2.2      (a)      1996 Award to International  Eligible Employees.  The
                           Directors  shall grant an Award to each Person who is
                           an  International  Eligible  Employee  on 31 December
                           1996.  For  purposes of the Plan,  31  December  1996
                           shall be deemed to be the Grant Date with  respect to
                           such award.  The total number of Shares available for
                           award in 1996 shall be determined in accordance  with
                           Appendix B. Such award shall be allocated pro rata to
                           all International Eligible Employees,  based on their
                           Annualized Base Compensation.

                  (b)      1996 Award to US Eligible  Employees.  The  directors
                           shall grant an Award to the US Eligible  Employees in
                           accordance with Appendix B.

                  (c)      1997 and  1998  Awards  to  Eligible  Employees.  Any
                           amounts that lapse in 1997 or 1998 in accordance with
                           Rules 5 and 6, shall be allocated to individuals  who
                           first become Eligible  Employees in the year of lapse
                           (i.e.,  those Eligible Employees hired in that year).
                           Such awards  shall be  allocated  pro rata,  based on
                           Annualized Base Compensation; provided, however, that
                           the  Award  to  any US  Eligible  Employee  shall  be
                           reduced  (not  below 0) by the  value of any  similar
                           reallocation   of   forfeitures   under  the  Covance
                           Employee Stock Ownership Plan.

                                       4

<PAGE>


                  (d)      1999 and  2000  Awards  to  Eligible  Employees.  Any
                           amounts that lapse in 1999 or 2000 in accordance with
                           Rule 5, shall be allocated to all Eligible  Employees
                           pro  rata  based  on  Annualized  Base   Compensation
                           provided, however, that the Awards to any US Eligible
                           Employee  shall be reduced (not below 0) by the value
                           of any similar  reallocation of forfeitures under the
                           Covance Employee Stock Ownership Plan.

         2.3      The  terms   attaching  to  an  Award  may  include,   without
                  limitation,  a  condition  that  the  granting  of an Award is
                  subject  to  the  surrender  for  cancellation  of  any or all
                  outstanding Awards held by the Eligible Employee.

         2.4      The Company shall issue to each  Eligible  Employee to whom it
                  has  granted  an  Award an Award  Certificate  which  shall be
                  executed  under  seal (or in such  other  manner as shall take
                  effect as a deed of the  Company)  and which  shall be in such
                  form as the Directors shall from time to time  determine.  The
                  Award Certificate shall include details of:

                  (a)      the Date of Grant of the Award;
                  (b)      the number of Restricted Shares.

         2.5      Each  Eligible  Employee  to whom an Award is  granted  may by
                  notice in writing within 30 days of the Date of Grant disclaim
                  in whole or in part his  rights  under the Award in which case
                  the Award shall for all  purposes be deemed never to have been
                  granted.

         2.6      Every Award shall be personal to the Eligible Employee to whom
                  it is granted and

                                       5

<PAGE>




                  shall  not  be  capable  of  being  transferred,  assigned  or
                  charged.  Each Award  Certificate  shall carry a statement  to
                  this effect.

3.       Conditions relating to the grant of Awards
         ------------------------------------------

         3.1      The Directors may determine that any Award shall be subject to
                  additional  and/or  modified terms and conditions  relating to
                  the grant and terms of exercise as may be  necessary to comply
                  with or take account of any  securities,  exchange  control or
                  taxation laws,  regulations or practice of any territory which
                  may have application to the relevant Eligible Employee,  Award
                  Holder or Member of the Group.

         3.2      In exercising  their  discretion  under Rule 3.1 the Directors
                  may:

                  (a)      require an Award Holder to make such  declarations or
                           take such other  action  (if any) as may be  required
                           for the  purpose  of any  securities,  taxes or other
                           laws of any territory  which may be applicable to him
                           at the  Date of  Grant  or at the end of the  Vesting
                           Period; and

                  (b)      adopt any supplemental rules or procedures  governing
                           Awards  as may be  required  for the  purpose  of any
                           securities,  tax or other laws of any territory which
                           may be  applicable  to an Eligible  Employee or Award
                           Holder.

         3.3      When  events  have  happened  which  cause  the  Directors  to
                  consider that any existing  constraints  and/or conditions (as
                  the case may be) have become unfair or impractical,  they may,
                  in their  discretion  (provided  such  discretion is exercised
                  fairly and reasonably), amend, relax, waive or substitute such
                  constraints   or  conditions  so  that  such   constraints  or
                  conditions so amended,  relaxed,  waived or substituted would,
                  in the reasonable opinion of the Directors, be no more or less
                  difficult   to  abide  by  or  satisfy  than  when  they  were
                  originally imposed or last amended or relaxed (as the case may
                  be).  After  any  such   amendment,   relaxation,   waiver  or
                  substitution  the Directors  shall issue to the Award Holder a
                  replacement  Award  Certificate or other notice  including the
                  details specified in Rule 2.4.


                                       6

<PAGE>



4.       Rights of Award Holder during Vesting Period
         --------------------------------------------

         4.1      During the Vesting  Period,  the Award  Holder shall not sell,
                  transfer, pledge, assign or otherwise dispose of all or any of
                  the Restricted Shares or any interest therein.  Any attempt by
                  the  Award  Holder  to  sell,  transfer,   pledge,  assign  or
                  otherwise  dispose of such Restricted  Shares, or any interest
                  therein shall result in immediate forfeiture of such Award.

         4.2      During the Vesting Period:

                  (a)      the   Trustees   shall   exercise  (or  refrain  from
                           exercising)  the  voting  rights   attaching  to  the
                           Restricted  Shares  subject  to Awards  made to those
                           Award  Holders in such  manner as they shall in their
                           absolute discretion think fit, and

                  (b)      all dividends and other distributions with respect to
                           such  Restricted  Shares  shall  be used  to  acquire
                           further  Restricted Shares which will be held subject
                           to the Awards to which they relate, and

                  (c)      any  scrip  dividends  shall be held  subject  to the
                           Awards to which they relate.

5.       Lapse of Awards
         ---------------

         Where any Award made under the Plan lapses,  the Shares subject to that
         Award shall be allocated in accordance with Rule 2.2.


                                       7

<PAGE>




6.       Termination of Vesting Period and Lapse of Awards
         -------------------------------------------------

         6.1      The Vesting Period shall  terminate on the January 1 following
                  the second  anniversary  of the Date of Grant or, if  earlier,
                  the date on which  the  Award  Holder  dies or ceases to be an
                  Eligible Employee by reason of what the Trustees consider,  in
                  their   absolute   discretion,   to  be  total  and  permanent
                  disability;  provided,  however, that any individual who is an
                  Eligible Employee on January 1, 2001 shall be fully vested.

         6.2      To the extent that a vesting period has not expired, the Award
                  shall lapse on the date on which an Award Holder  ceases to be
                  an Eligible Employee by reason of a termination of employment.

7.       Release of Restricted Shares
         ----------------------------

         When the Vesting  Period in relation  to an Award  ends,  the  relevant
         Restricted Shares shall be allotted or transferred (as the case may be)
         to the Award Holder as soon as possible and, accordingly in cases where
         Restricted Shares are to be transferred, the Company shall use its best
         endeavours to ensure due transfer thereof.

8.       Issue of Shares
         ---------------

         8.1      All Shares  issued  pursuant to Awards under the Plan shall as
                  to voting,  dividend,  transfer  and other  rights  (including
                  those  arising  on a  liquidation)  rank  pari  passu  in  all
                  respects with the Shares then in issue, except that they shall
                  not  rank  for  any  dividend  or  other  rights  declared  by
                  reference to a record date preceding the date of issue.

         8.2      If and so long as the Shares are listed on the [New York Stock
                  Exchange] the Company shall use its best endeavours to procure
                  that as soon as practicable after

                                       8

<PAGE>




                  the allotment of any Shares pursuant to the Plan application
                  shall be made to the [New York Stock Exchange] for admission
                  of the Shares to dealing.

9.       Discretion as to Form of Payment
         --------------------------------

         9.1      On  termination of the Vesting Period in relation to an Award,
                  any  Award  shall be paid in  Shares,  except  that,  in their
                  discretion,   the  Directors  may  in  lieu  of  allotting  or
                  procuring  the  transfer  of any or all  Restricted  Shares in
                  accordance  with  Rule 7 pay to such  Award  Holder a cash sum
                  equal to the value of such Restricted Shares (being the middle
                  market  quotation  on the [New York  Stock  Exchange]  for the
                  first Dealing Day following the end of the Vesting Period).

         9.2      If payment is made  pursuant to this Rule to an Award  Holder,
                  he shall have no further rights in respect of such  Restricted
                  Shares. The Company may make any deductions in respect of such
                  payment  which it is  required  to make  under the laws of any
                  territory which laws are applicable to the Award Holder and/or
                  his employing Member of the Group.

10.      Adjustments
         -----------

         10.1     The  number of  Restricted  Shares  subject to an Award may be
                  adjusted in such manner as the Directors  shall determine (and
                  which the  Auditors  shall  confirm  in writing to be in their
                  opinion  fair and  reasonable)  following  any  capitalisation
                  issue,  subdivision,   consolidation  or  reduction  of  share
                  capital and in respect of any  discount  element in any rights
                  issue or other  variation of share  capital to the intent that
                  (as nearly as may be possible without involving fractions of a
                  Share the value of the Award shall remain unchanged.


                                       9

<PAGE>



         10.2     The  Directors  may  take  such  steps  as they  may  consider
                  necessary  to notify  Award  Holders of any  adjustments  made
                  under  Rule  10.1 and to call in,  cancel,  endorse,  issue or
                  re-issue   any   Award   Certificate   consequent   upon  such
                  adjustment.

11.      Administration
         --------------

         11.1     Notices  or  documents  required  to be given  to an  Eligible
                  Employee or to an Award  Holder  shall  either be delivered to
                  him by hand or sent to him by first class post pre-paid at his
                  last  known  home  or  business   address   according  to  the
                  information  provided  by him.  Notices  sent by mail shall be
                  deemed to have been given on the  seventh  day  following  the
                  date of posting.

         11.2     The  Company may  distribute  to Award  Holders  copies of any
                  notice or  document  sent by the  Company to its  shareholders
                  generally.

         11.3     The  Company   shall  at  all  times  either  keep   available
                  sufficient  unissued  Shares  to  satisfy  all  extant  Awards
                  (taking  account of any other  obligations  of the  Company to
                  allot unissued Shares) or shall ensure that sufficient  issued
                  Shares  will be  available  to satisfy  the  exercise  of such
                  Awards.

         11.4     The Directors may make such regulations for he  administration
                  of the Plan as they  deem  fit,  provided  that no  regulation
                  shall be  valid  to the  extent  it is  inconsistent  with the
                  Rules.

         11.5     The decision of the  Directors  in any dispute  relating to an
                  Award,  or the due  exercise  thereof,  or any other matter in
                  respect of the Plan, shall be final and conclusive, subject to
                  the determination of the Auditors, when so required by Rule

                                       10

<PAGE>



         11.6     The costs of establishing and  administering  the Plan and the
                  associated  costs  of  making  Awards  shall  be  borne by the
                  Participating  Employers in such  proportions as the Directors
                  think fit.

         11.7     Any stamp  duty  chargeable  on the  instruments  of  transfer
                  entered into pursuant to each Award  Agreement  shall be borne
                  by the Company, or where relevant,  any Participating Employer
                  of Award Holders employed by it.

12.      Alterations
         -----------

         12.1     Subject to Rule 12.2,  the Directors  may in their  discretion
                  alter the Rules.

         12.2     No  alteration  may be made which would  abrogate or adversely
                  affect the subsisting rights of Award Holders.

         12.3     Written notice of any amendment  made in accordance  with this
                  Rule 12 shall be given to all Award Holders.

13.      General
         -------

         13.1     The Plan shall terminate on the tenth  anniversary of the date
                  on which it is approved  by the Company in general  meeting or
                  at any  earlier  time by the  passing of a  resolution  by the
                  Directors.  Termination of the Plan shall be without prejudice
                  to the subsisting rights of Award Holders.

         13.2     If an Award  Holder  shall  cease for any  reason to be in the
                  employment  of a  Participating  Employer,  he  shall  not  be
                  entitled,  by  way of  compensation  for  loss  of  office  or
                  otherwise  howsoever,  to any sum or any benefit to compensate
                  him for  the  loss  of any  right  or  benefit  accrued  or in
                  prospect under the Plan.

                                       11

<PAGE>




         13.3     This Plan and all Awards shall be governed by and construed in
                  accordance with English law.

                                       12

<PAGE>



                                   APPENDIX A1
                      International Participating Companies

         CORNING Bessalear Limited (England)
         CORNING Bessalear Limited (Ireland)
         GHBA A.G.
         CORNING Bessalear AG
         G.H. Bessalear Associates GmbH
         CORNING Bessalear Pty. Ltd.
         CORNING Bessalear S.A.
         CORNING Bessalear SARL
         CORNING Hazleton GmbH
         CORNING SciCor S.A.
         CORNING Pharmaceutical Services Ltd.
         CORNING Bessalear Ltd.
         CORNING Bessalear CRU Ltd.
         CORNING Hazleton Ltd.
         CRS Pacmed A.G.


                                       13

<PAGE>



                                   APPENDIX A2
                          U.S. Participating Companies

         COVANCE INC. (f/k/a Corning Pharmaceutical Services Inc.)(Delaware)
         Covance  Clinical  and   Periapproval   Services  Inc.  (f/k/a  Corning
          Besselaar Inc.)(New Jersey)
         Covance Clinical Research Unit Inc. (f/k/a Corning  Besselaar  Clinical
          Research Units Inc.)(Florida)
         Covance Periapproval Services Inc. (f/k/a Corning Pact Inc.)(Delaware)
         Covance   Preclinical    Corporation   (f/k/a   Hazleton   Corporation)
          (Washington)
         Covance Laboratories Inc. (f/k/a/ Corning Hazleton Inc.)(Delaware)
         Covance Research Products Inc. (f/k/a HRP Inc.)(Pennsylvania)
         Covnace Central Laboratory Services Inc. (f/k/a Corning SciCor Inc.)
         Covance Central  Laboratory  Limited  Partnership  dba Covance  Central
          Laboratory    Services   Inc.    (f/k/a/    Corning   SciCor   Limited
          Partnership)(Indiana)
         Covance Pharmaceutical  Packaging Services Inc. (f/k/a Corning National
          Packaging Inc.)(Connecticut)
         Covance Health  Economics and Outcome  Services Inc. (f/k/a Corning HTA
          Inc.)(Delaware)
         Covance  Biotechnology  Srvices Inc. (f/k/a Corning Bio Inc.)(Delaware)
         Pharmaceutical Laboratory Services Inc.



                                       14

<PAGE>




                           APPENDIX B: 1996 ALLOCATION
            The 1996 Total allocation shall be determined as follows:

         1.  1996 Total Allocation: The 1996 total allocation shall be
             determined as follows: The total allocation of shares to the
             Covance Employee Stock Ownership Plan ("ESOP") and the Plan shall
             equal to 1.5% of the Shares outstanding on 31 December 1996, with
             such determination being made before such allocation.

         2.  Aggregate International Base Compensation and Aggregate US Base
             Compensation. Aggregate International Base Compensation shall equal
             the sum of the Annualized Base Compensation (converted to US
             dollars) for each individual who is an International Eligible
             Employee on 31 December 1996. The Aggregate US Base Compensation
             shall equal the sum of the Annualized Base Compensation for each
             individual who is a US Eligible Employee on 31 December 1996. Total
             Aggregate Base Compensation shall be the sum of the Aggregate
             International Base Compensation and the Aggregate US Base
             Compensation.

         3.  Allocation Between Plans. The portion of the 1996 Total Allocation
             shall be divided into the International Portion and the US Portion
             as follows: (i) first, shares having a value equal to 1% of
             Aggregate International Compensation shall be allocated to the
             International Portion and (ii) next, the remainder of the 1996
             Total Allocation shall be allocated to the International Portion
             and the US portion in the proportions represented by Aggregate
             International Compensation and Aggregate US Compensation
             respectively.

         4.  Award to International Eligible Employees Under this Plan. The
             International Portion shall be allocated to International Eligible
             Employees under this Plan in accordance with Rule 2.2 (a) hereof.

                                       15

<PAGE>



         5.  Award to US Eligible Employees. The Awards to US Employees under
             this Plan shall be determined as follows:

              (a)  For each US Eligible Employee, determine the amount of Award,
                   based on the US Portion (as determined above) that would be
                   provided under the ESOP, without regard to the limitations
                   imposed by Sections 415 and 401(a)(17) of the Code.

              (b)  For each US Eligible Employee, determine the amount of award,
                   based on the US Portion (as determined above) that would be
                   provided under the ESOP, after application of the limitations
                   imposed by Sections 415 and 401(a)(17) of the Code. This
                   amount shall be awarded under the ESOP to such individuals.

              (c)  The difference between (a) and (b) above shall be awarded to
                   each US Eligible Employee under this Plan.


                                       16

                              Employment Agreement
                                     between
                               Christopher Kuebler
                                        &
                                  Covance Inc.

         This EMPLOYMENT AGREEMENT (the "Agreement") is entered into between
COVANCE INC. (formerly Corning Pharmaceutical Services Inc.) (the "Company"), a
Delaware corporation having its principal place of business at 210 Carnegie
Center, Princeton, NJ 08540- 6233, and CHRISTOPHER KUEBLER (the "Executive"),
with a residence at 9 Woodland Road, Newtown, PA 18940 as of November 1, 1996
(the "Effective Date").

         WHEREAS, Executive has been employed by the Company as President and
Chief Executive Officer; and

         WHEREAS, the Company considers the services of the Executive to be
unique and essential to the success of the Company's business; and

         WHEREAS, the Company and the Executive now wish to enter into an
agreement of employment that will constitute the sole and exclusive agreement
relating to the employment of Executive by the Company on the terms and
conditions set forth herein.

         NOW, THEREFORE, in consideration of the foregoing premises, the mutual
covenants, terms and conditions set forth herein, and other valuable
consideration, the receipt and sufficiency of which are hereby acknowledged, it
is hereby agreed between the Corporation and the Executive as follows:

     I.    Employment: The Company shall continue to employ the Executive in a
           full-time capacity in the position set forth in this paragraph, and
           the Executive shall continue to accept such employment upon the terms
           and conditions set forth herein. Such



<PAGE>


Employment Agreement Between
Corning Pharmaceutical Services, Incorporated & Christopher Kuebler
Draft #3 (Printed: 11/18/96 - 2:10 PM)
Page 2




           employment shall be in the capacity of President and Chief Executive
           Officer of the Company, and Chairman of the Board of Directors of the
           Company.


     II.   Term: Unless earlier terminated pursuant to Section IX hereof, the
           term of employment under the agreement shall commence on the
           Effective Date and shall continue through the third anniversary of
           the Effective Date (such initial term, as it may be extended from
           time to time in accordance with Section XVI or shortened pursuant to
           Section IX hereof being, the "Employment Term").


     III.  Duties: During the Employment Term, the Executive shall accept and
           diligently perform to the reasonable satisfaction of the Company,
           those executive services for the Company as may be commensurate with
           his position and title and as may be designated from time to time by
           the Company's Board of Directors in connection with any aspect of the
           Company's business. The Executive agrees to devote his undivided time
           and attention to the business of the Company. The Executive shall
           not, without the prior written consent of the Company's Board of
           Directors, be directly or indirectly engaged in any other trade,
           business or occupation for compensation requiring his personal
           services during the Employment Term. Nothing in this agreement shall
           preclude the Executive from: (i) engaging in charitable and community
           activities or from managing his personal investments, or (ii) serving
           as a member of the board of directors of an unaffiliated company not
           in competition with the Company, subject however in each such case of
           board membership, to approval by the Company's Board of Directors
           (which approval shall not be unreasonably withheld).




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     IV.   Cash Compensation: Executive shall be compensated for services
           rendered during the Employment Term as follows:

           (a) Base Salary: Effective from and after the consummation of the
           spin-off described in Section XIX of this Agreement, Executive shall
           be compensated at an annual base salary of no less than $450,000 for
           the period during which he serves as President and Chief Executive
           Officer of the Company. The Company's Board of Directors shall review
           and may, if appropriate, at its discretion, increase (but not
           decrease) this annual base salary effective the first day of any
           future new year during the Employment Term to reflect ordinary salary
           actions generally granted to other Company employees.

           (b) Variable (bonus) Pay: In addition to the Base Salary provided for
           in Section IV(a) above, Executive will participate in the Company's
           Variable Compensation Plan (the "Bonus Plan"). The Bonus Plan
           provides that upon satisfaction of certain goals for the Company
           established by the Company's Board of Directors, Executive shall
           receive an annual incentive equal to 65% of Executive's annual base
           salary in effect at the time the goals are established; provided,
           however, that Executive's payout, if any, under the Bonus Plan for
           1997 shall be computed using his salary specified in Section IV (a)
           hereof.

           The Bonus Plan also provides that Executive may earn up to 130% of
           Executive's annual base salary in effect at the time the goals are
           established if the Company has outstanding results, again as
           determined by the Company's Board of Directors. At the discretion of
           the Company's Board of Directors, any annual incentive compensation
           in excess of 65% of Executive's annual base salary may be paid to
           Executive in non-qualified stock options, the terms of which would be
           specified in a Stock Option Agreement entered into pursuant to the
           Company's Employee Equity Participation Program. Actual awards would
           be determined by the Company's Board

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           of Directors after the end of the applicable performance year and
           would be granted to Executive shortly thereafter. The annual
           incentive percentage targets may be increased, but not decreased,
           during the Employment Term.

     V.    Equity /Awards: Executive may be awarded, from time to time,
           additional compensation (such as stock options or restricted stock)
           pursuant to the Company's Employee Equity Participation Program or
           any additional or replacement incentive compensation or long-term
           compensation program established for the senior officers of the
           Company. Any awards under such programs, except as provided below,
           shall be at such levels or in such amounts as the Company's Board of
           Directors deems, in its sole discretion, appropriate for the position
           occupied by Executive and his performance therein. The terms,
           conditions and rights with respect to any such grants will be subject
           to the actual provisions and conditions applicable to such plans.

           In conjunction with the Executive's first year participation in the
           Company's Employee Equity Participation Program, the Company shall
           grant to the Executive, on the terms set forth below, that number of
           shares of the Company's common stock, subject to certain restrictions
           (the "Restricted Stock"), and options to purchase the Company's
           common stock (the "Stock Options"), that have in the aggregate a
           present value equal to not less than $1,619,982 (the "First Grant
           Value"). The First Grant Value shall consist of Stock Options and
           Restricted Stock in the ratio of three Stock Options for every share
           of Restricted Stock. Each Stock Option shall be worth a present value
           amount equal to the product of (i) the fair market value of the
           Company's common stock and (ii) .33. The fair market value of the
           Company's common stock shall be determined based on the weighted
           average per share price of each trade of the Company's common stock
           occurring during normal trading hours of the first five days of
           "regular way" trading after completion of the spin-off described in
           Section XIX hereof. The rights, obligations and other conditions of
           the Restricted Stock and Stock

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           Options shall be as specified in that certain Incentive Stock
           Agreement and Stock Option Agreement, in each case, between Executive
           and the Company.


     VI.   Employee Benefits:

           (a) General Provisions: Except as expressly provided in this
           Agreement, Executive shall be eligible to participate in all employee
           benefit plans offered by the Company (e.g. Life Insurance, Medical &
           Dental Insurance, Travel Accident Insurance, Short Term Disability
           Insurance, Long Term Disability Insurance, Flexible Spending
           Accounts, Regular and Supplemental Accidental Death and Disability
           Insurance, Optional/Supplemental Life Insurance, Stock Purchase
           Savings Plan (401(k)), Employee Stock Purchase Program, Employee
           Stock Ownership Plan, and other personal benefit plans of the
           Company) on a basis which is no less favorable to the Executive than
           the Company may make available to other senior officers of the
           Company; provided, however, that in all events the eligibility and
           other terms of any such plans shall govern the participation of the
           Executive therein.

           (b) Supplemental Executive Retirement Plan: Executive will be
           eligible to participate in the Company's Supplemental Executive
           Retirement Plan (SERP). Under the terms of the SERP, Executive will
           be entitled to receive a nonqualified retirement benefit in
           accordance with the terms and provisions thereof, as administered by
           the Company's Board of Directors.

           (c) Vacation and Sick Leave: Executive shall be entitled to vacation
           and sick leave in accordance with the vacation and sick leave
           policies adopted by the Company from time to time, provided that the
           Executive shall be entitled to no less than five (5) weeks of
           vacation each calendar year. Any vacation shall be at such times and
           for such


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           periods as shall be mutually agreed upon between the Executive and
           the Company. The Executive shall be entitled to all public holidays
           observed by the Company.


     VII.  Applicable Taxes: There shall be deducted from any compensation
           payments made under this Agreement any Federal, state and local taxes
           or other amounts required to be withheld by any entity having
           jurisdiction over the matter.


     VIII. Miscellaneous:

           (a) Business Travel and Expenses: Executive shall be reimbursed by
           the Company for reasonable travel and other business expenses, as
           approved by the Company, which are incurred and shall be accounted
           for in accordance with the Company's normal practices and procedures
           for reimbursement of expenses.

           (b) Housing Loan: There will be no change in the terms of Executive's
           outstanding housing loan arrangement with the Company.

           (c) Automobile Expenses: The Company will provide Executive with a
           gross automobile allowance of $1,070 per month (or other such monthly
           amount as is provided to other senior executives of the Company in
           accordance with the provisions of the Company's auto allowance
           program). Such amounts will be disclosed for purposes of Securities
           and Exchange Commission filings as appropriate or required.

           (d) Financial Counseling and Legal Services: The Company will provide
           an annual allowance of $10,000 (grossed-up for tax purposes using an
           incremental income tax rate of 45%) for the Executive to use for
           financial counseling, tax preparation and legal


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           services. Such amounts will be disclosed for purposes of Securities
           and Exchange Commission filings as appropriate or required.

           (e) Ongoing Non-Exclusivity: Nothing in this Agreement shall prevent
           the Executive from being entitled to receive any additional
           compensation or benefits as approved by the Company's Board of
           Directors and which would amend or supplement the compensation or
           benefits specified in this Agreement.


     IX.   Termination of Employment: Notwithstanding any other provision of
           this Agreement, the employment of the Executive pursuant to this
           Agreement may be terminated by the Company's Board of Directors as
           follows:

           (a) Termination For Cause: Executive may be terminated at any time
           during the Employment Term for "Cause". As used herein, the term
           "Cause" shall mean (i) conviction of the Executive of a felony or
           conviction of a misdemeanor if such misdemeanor involves moral
           turpitude; (ii) Executive's committing any act of gross negligence or
           intentional misconduct in the performance or non-performance of his
           duties as an employee of the Company, including any such actions
           which constitute sexual harassment under applicable laws, rules or
           regulations; (iii) if Executive is not disabled (as defined below), a
           failure or refusal to perform the duties and services specified
           herein for a period of not less than thirty (30) days; (iv) any
           material breach by the Executive of any material provision of this
           Agreement (other than for reasons related only to the business
           performance of the Company or business results achieved by the
           Executive); or (v) misappropriation of Company assets or personal
           dishonesty which causes financial or reputational harm with respect
           to the Company.

           

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           For purposes of this section, no act or failure to act on Executive's
           part shall be considered to be reason for termination for Cause if
           done, or omitted to be done, by

           Executive in good faith and with the reasonable belief that the
           action or omission was in the best interests of the Company.

           (b) Termination For Disability: At the sole discretion of the
           Company's Board of Directors, Executive may be terminated if the
           Executive is disabled (as defined below) and shall have been absent
           from his duties with the Company on a full-time basis for one hundred
           and twenty (120) consecutive days, and within thirty (30) days after
           written notice by the Company to do so, the Executive shall not have
           returned to the performance of his duties hereunder on a full-time
           basis. In the event of such termination, the Company shall make to
           Executive the payments specified in Section IX(c). As used herein,
           the term "disabled" shall (i) mean that the Executive is unable, as a
           result of a medically determinable physical or mental impairment, to
           perform the duties and services of his position, or (ii) have the
           meaning specified in any disability insurance policy maintained by
           the Company, whichever is more favorable to the Executive.

           (c) Severance Benefits: Executive's employment may be terminated
           without Cause if the Company's Board of Directors, upon assessment of
           the general business performance of the Company and the specific
           performance of the Executive, determines that the business needs of
           the Company require the replacement of the Executive, provided that
           in such event:

              (i) Executive shall be entitled to receive three (3) years base
              salary (at the Executive's effective annual rate on the date of
              termination) which amount shall be paid in a lump-sum (net of
              appropriate withholdings) within sixty (60) days of the date of
              termination; and



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              (ii) Executive shall be entitled to receive an amount equal to the
              product of (A) three (3), (B) the Executive's annual base salary
              in effect at the time of termination, and (C) the higher of 65%
              and the then applicable annual incentive percentage specified in
              the Bonus Plan, which amount shall be paid in a lump-sum (net of
              appropriate withholdings) within sixty (60) days of the date of
              termination; and

              (iii) Executive shall be entitled to continue participation in the
              Company's health and benefit plans (to the extent allowable in
              accordance with the administrative provisions of those plans and
              applicable federal and state law) for a period of up to three (3)
              years or until Executive is covered by a successor employer's
              benefit plans, whichever is sooner.

           (d) Change-of-Control: Should Executive's employment be terminated by
           the Company (for reasons other than Cause), or should Executive's
           duties as President and Chief Executive Officer of the Company be
           diminished in any respect (a "Constructive Termination") (either
           event being referred to herein as an "Event of Termination"), within
           twelve (12) months following a "Change-Of-Control" (as defined
           below), Executive will be entitled to receive all of the "Severance
           Benefits" described in paragraph (c) above, and, in addition:

              (i) All stock options (including the Stock Options), restricted
              stock (including the Restricted Stock), deferred compensation and
              similar benefits which have not become vested on the date of an
              Event of Termination shall become vested upon such Event.

              (ii) The Executive shall be entitled to receive any payments
              calculated pursuant to Section XVIII hereof.



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Draft #3 (Printed: 11/18/96 - 2:10 PM)
Page 10


           For purposes of this Agreement, a Change-Of-Control is defined to be:

              (i) any person (including as such term is used in Section 13(d)
              and 14(d)(2) of the Securities Exchange Act of 1934) becomes the
              beneficial owner, directly or indirectly, of Company securities
              representing 20% or more of the combined voting power of the
              Company's then outstanding securities; or

              (ii) as a result of a proxy contest or contests or other forms of
              contested shareholder votes (in each case either individually or
              in the aggregate), a majority of the individuals elected to serve
              on the Company's Board of Directors are different then the
              individuals who served on the Company's Board of Directors at any
              time within the two years prior to such proxy contest or contests
              or other forms of contested shareholder votes; or

              (iii) the Company's shareholders approve a merger or consolidation
              (where in each case the Company is not the survivor thereof), or a
              sale or disposition of all or substantially all of the Company's
              assets or a plan of partial or complete liquidation; or

              (iv) an offerer (other than the Company) purchases shares of the
              Company's common stock pursuant to a tender or exchange offer for
              such shares.

           (e) Except as may be otherwise provided in applicable Company
           compensation & benefit plans, the Company shall not be liable for any
           salary or benefit payments to Executive beyond the date of
           Executive's voluntary termination of employment with the Company. In
           the event of a termination of employment under Sections IX(a) or
           IX(b) above, the Executive shall not be entitled to any compensation
           or other benefits 


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Draft #3 (Printed: 11/18/96 - 2:10 PM)
Page 11


           not already earned and owing to the Executive on account of his
           services on the date of such termination of employment.

           (f) Outplacement Assistance: In the event Executive is involuntarily
           terminated or Constructively Terminated as a result of a Change of
           Control or for other reasons that do not constitute Cause, the
           Company shall provide for Executive, at the Company's cost, executive
           outplacement support for one-year following such termination.


     X.    Arbitration: In the event of any difference of opinion or dispute
           between the Executive and the Company with respect to the
           construction or interpretation of this Agreement or the alleged
           breach thereof, which cannot be settled amicably by agreement of the
           parties, then such dispute shall be submitted to and determined by
           arbitration by a single arbiter in the city of Trenton, New Jersey in
           accordance with the rules then in effect, of the AMERICAN ARBITRATION
           ASSOCIATION, and judgment upon the award rendered shall be final,
           binding and conclusive upon the parties and may be entered in the
           highest court, state or federal, having jurisdiction.

           The Company shall reimburse Executive for all expenses incurred by
           Executive in connection with any arbitration, including the
           reasonable costs and expenses of legal counsel, to the extent the
           arbitration is concluded in the Executive's favor.


     XI.   Confidentiality: The Company possesses and will continue to possess
           trade secrets or other information which has been crafted,
           discovered, developed by or otherwise become known to the Company, or
           in which property rights have been assigned or otherwise conveyed to
           the Company, which information has commercial value with respect to
           the business and operations of the Company or the business and
           operations of 

                                       11


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Page 12




              its subsidiaries or its affiliates, including, but not limited to,
              information regarding sales, costs, customers, employees,
              products, services, apparatus, equipment, processes, formulae,
              marketing, or the organization, business or finances of the
              Company or its subsidiaries or its affiliates, or any information
              the Executive has reason to know the Company would like to treat
              as confidential for any purpose, such as maintaining a competitive
              advantage or avoiding undesirable publicity, whether or not
              developed by the Executive ("Confidential Information"). Unless
              previously authorized in writing or instructed in writing by the
              Company, the Executive will not, from and after the date of
              employment with the Company, directly or indirectly, use for his
              own benefit or purposes, or disclose to, or use for the benefit or
              purposes of, anyone other than the Company or its subsidiaries or
              affiliates, any Confidential Information, unless and until, and
              then only to the extent that, such Confidential Information has
              (a) been or becomes published, or is or becomes generally known in
              the trade through no fault of the Executive, or (b) such
              information is made known and available to the Executive by a
              third party, who, by such disclosure to the Executive does not
              breach any duty or obligation to the Company or its subsidiaries
              or affiliates.

           In the event the Executive become legally compelled to disclose any
           of the Confidential Information, the Executive will provide the
           Company with prompt notice so that the Company may seek a protective
           order or other appropriate remedy and/or waive compliance with the
           provisions of this Agreement. If, in the absence of a protective
           order or the receipt of a waiver hereunder, the Executive is
           nonetheless legally required to disclose Confidential Information to
           any tribunal or else stand liable for contempt or suffer other
           censure or penalty, the Executive may disclose such Confidential
           Information to such tribunal without liability hereunder.

           Upon termination of the Executive's employment with the Company, he
           will deliver to the Company all written embodiments of the
           Confidential Information, including all




                                       12


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Page 13


           notes, drawings, records, and reports pertaining to work done by the
           Executive during the Employment Term and all other matters of secret
           or confidential nature relating to the Company's business.

     XII.  Non-Competition. The Executive acknowledges that the services to be
           rendered by the Executive to the Company are of a special and unusual
           character, with a unique value to the Company, the loss of which
           cannot adequately be compensated by damages or an action at law. In
           view of the unique value to the Company of such services for which
           the Executive is employed at the Company, because of the Confidential
           Information obtained by, or disclosed to the Executive, and as a
           material inducement to the Company to compensate the Executive as
           well as provide him with additional benefits and other good and
           valuable consideration, the Executive covenants and agrees that:

           (a) Unless authorized by the Company's Board of Directors in writing,
           Executive shall not, during the Employment Term and for one year
           after the expiration of the Employment Term (the "Post Employment
           Term", the Employment Term and the Post Employment Term, being
           collectively, the "Period"), become employed by, become a director,
           officer, shareholder or partner of, or to otherwise enter into,
           conduct, or advise any business, whether directly or indirectly,
           which offers services or products in the United States and any other
           geographical regions where the Company, or its subsidiaries or its
           affiliates, is then offering its services or products in competition
           with services or products sold by the Company, or its subsidiaries or
           its affiliates at any time during the Period in the United States or
           such region, including, without limitation, the conduct of contract
           pre-clinical toxicology laboratory services, contract
           biopharmaceutical clinical laboratory services, contract
           bioprocessing or manufacturing services, contract drug packaging
           services, Phase I, II, III or IV clinical studies or 


                                       13


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Page 14




           outcomes or disease management studies (collectively, the "Company
           Services"); provided that the Executive shall not be bound by the
           restrictions contained in this Section XII(a) unless the Company has
           made all payments to the Executive which are due and owing to the
           Executive under this Agreement or any plan of the Company, including
           any equity incentive plan or bonus incentive plan of the Company, or
           otherwise; provided, further, that if Executive has been dismissed by
           the Company for Cause, or Executive has voluntarily terminated his
           employment with Covance for any reason or no reason, Executive shall
           not be bound by the provisions of this Section XII(a) during the Post
           Employment Term unless the Company has made to the Executive the
           payments specified in Section IX(c) of this Agreement. Nothing herein
           shall restrict Executive in his employment in any capacity by a
           corporation or entity engaged substantially in the manufacture or
           sale of pharmaceuticals, or any other business which does not offer
           the Company Services. Ownership of not more than 1% of the issued and
           outstanding shares of any class of securities of a corporation, the
           securities of which are traded on a national securities exchange or
           in the over-the-counter market, shall not cause Executive to be
           deemed a shareholder under this provision.

           (b) During the Period, the Executive shall not, directly or
           indirectly, solicit, divert or accept any business from any customer
           of the Company, its subsidiaries or affiliates to the detriment of
           any of the foregoing or seek to cause any such customers to refrain
           from doing business with or patronizing the Company, its subsidiaries
           or its affiliates.

           (c) During the Period, the Executive shall not, directly or
           indirectly, solicit or induce for employment any employee of the
           Company, its subsidiaries or affiliates or otherwise encourage any
           employee of the Company, its subsidiaries or affiliates to leave the
           Company, or any of its subsidiaries or affiliates. For purposes of
           this Agreement, advertisements in trade magazines, use of executive
           search firms and other conventional 


                                       14


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Page 15




           means of obtaining employees shall not be construed as solicitation,
           inducements or encouragement unless the party utilizing such
           conventional means specifically directs the efforts at employee(s)
           with whom the party may not have contact pursuant to the terms of
           this Agreement.

           (d) For purposes of this Agreement, the term "directly or indirectly"
           shall be construed in its broadest sense and shall include the
           activities of the members of the Executive's immediate family or any
           partnership, or as otherwise specified above, and the term "customer"
           shall mean any person or entity to which the Company has sold
           services during the one-year period prior to the date the Executive
           ceased employment with the Company or any persons or entities
           targeted by the Company or contacted for the purpose of selling such
           services during such one-year period which Executive knew about or
           reasonably should have known about.


     XIII. Ownership of Know-How, Inventions and Other Intellectual Property:
           All the know-how, innovations, inventions, discoveries, improvements,
           procedures, programs, formulae and specifications which have been or
           may be either, directly or indirectly, developed, conceived or made
           by the Executive in connection with the Executive's employment with
           the Company, whether or not in concert with other employees or shown
           or delivered to the Company, or any of its subsidiaries or its
           affiliates, and whether or not they are eligible for patent,
           copyright, trademark, trade secret or other legal protection, shall
           be the exclusive property of the Company and the Executive shall, at
           the Company's request and expense, promptly execute any and all
           documents or instruments which may be necessary to evidence such
           ownership.

           Obligations of this Agreement cover any and all inventions,
           discoveries or improvements, directly or indirectly, conceived or
           made by the Executive in connection 


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Page 16




           with the Executive's employment with the Company prior to the date of
           this Agreement.

           The Executive will communicate to the Company promptly and fully all
           improvements and inventions he makes or conceives (either solely or
           jointly with others) during the period of the Executive's employment
           with the Company and conceived by the Executive, during the Post
           Employment Term if based on or related to his employment at the
           Company.

     XIV.  Patents: The Executive will, during and after the Period at the
           Company's request and expense but without additional compensation,
           assist the Company and its nominees in every proper way to obtain and
           to vest in the Company or its nominees, title to patents on such
           improvements and inventions in all countries, by executing all
           necessary or desirable documents, including applications for patents
           and assignments thereof.


     XV.   Records and Documents: Except in the performance of his duties as an
           Executive of the Company, the Executive will not at any time or in
           any manner make or cause to be made any copies, pictures, duplicates,
           facsimiles, or other reproductions, recordings, abstracts, or
           summaries of any reports, studies, memoranda, correspondence,
           manuals, customer lists, software, records, formulae, plans or other
           written, printed, or otherwise recorded material of any kind whatever
           belonging to or in the possession of the Company or its subsidiaries
           or affiliates, which may be produced or created by the Executive or
           others or which may come into the Executive's possession in the
           course of his employment, or which relate in any manner to the then
           current or prospective business of the Company, its subsidiaries or
           its affiliates. The Executive shall have no right, title or interest
           in any such materials, and the Executive agrees that he has not


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Page 17



           removed and will not remove such materials without the prior written
           consent of the Company or its subsidiaries or affiliates, and that he
           will surrender all such material to the Company immediately upon
           expiration of the Employment Term, or at any time prior thereto upon
           the request of the Company.


     XVI.  Renewal: At the expiration of the initial term or any subsequent
           term, the term of the Agreement may be extended for a period as
           determined by the mutual agreement of the Executive and the Company's
           Board of Directors. Notice of any such extension shall be provided to
           the other party not earlier than six months and not later than three
           months prior to the expiration of the existing term. The Company
           shall be under no obligation to extend the term of this Agreement if
           the Executive has engaged in actions or inactions which would
           constitute reasons to dismiss the Executive for Cause. If the Company
           decides not to renew the term of this Agreement (including any
           renewal after initial the term and any subsequent or successor term
           or terms) for any reason other than Cause, the Company shall make to
           the Executive all of the payments specified in Section IX(c) and on
           the terms of such Section.


     XVII. Other Matters:

           (a) Entire Agreement: This Agreement constitutes the entire agreement
           between the Company and the Executive relating to the subject matter
           hereof, and supersedes any previous agreements, commitments and
           understandings, written or oral, with respect to the matters provided
           herein, except as expressly provided in Section XI hereof. As used in
           this Agreement, terms such as "herein", "hereof", "hereto" and
           similar language shall be construed to refer to this entire
           instrument and not merely the paragraph or sentence in which they
           appear, unless so limited by express language.



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           (b) Assignment: Except as set forth below, this Agreement and the
           rights and obligations contained herein shall not be assignable or
           otherwise transferable by either party to this Agreement without the
           prior written consent of the other party to this Agreement.
           Notwithstanding the foregoing, any amounts owing to the Executive
           upon his death with respect to a portion of the Employment Term prior
           to the executive's death shall inure to the benefit of his heirs,
           legatees, personal representatives, executor or administrator.

           (c) Notices: Any and all notices provided for under this Agreement
           shall be in writing and hand delivered or sent by first class
           registered or certified mail, postage prepaid, return receipt
           requested, or by reputable overnight courier, or by telecopier (with
           return telecopy), addressed to the Executive at his residence or to
           the Company at its usual place of business or at any other address
           specified in writing and provided to the other party hereto, and all
           such notices shall be deemed effective at the time of delivery or at
           the time delivery is refused by the addressee upon presentation.

           (d) Amendments/Waiver: No provision of this Agreement may be amended,
           waived, modified, extended or discharged unless such amendment,
           waiver, extension or discharge is agreed to in writing signed by both
           the Company and the Executive.

           (e) Applicable Law: This Agreement and the rights and obligations of
           the parties hereunder shall be construed, interpreted, and enforced
           in accordance with the laws of the State of New Jersey.

           (f) Severability: The Executive hereby expressly agrees that all of
           the covenants in this Agreement are reasonable and necessary in order
           to protect the Company and its business. If any provision or any part
           of any provision of this Agreement shall be


                                       18


<PAGE>


Employment Agreement Between
Corning Pharmaceutical Services, Incorporated & Christopher Kuebler
Draft #3 (Printed: 11/18/96 - 2:10 PM)
Page 19


           invalid or unenforceable under applicable law, such part shall be
           ineffective only to the extent of such invalidity or unenforceability
           and shall not affect in any way the validity or enforceability of the
           remaining provisions of this Agreement, or the remaining parts of
           such provision.

           (g) Successor of Interests: In the event the Company merges or
           consolidates with or into any other corporation or corporations where
           the Company is not the survivor thereof, or sells or otherwise
           transfers substantially all its assets to another corporation, the
           provisions of this Agreement shall be binding upon and inure to the
           benefit of the corporation surviving or resulting from the merger or
           consolidation or to which the assets are sold or transferred and,
           upon any such event, the Company shall obtain the assumption of this
           Agreement by the other corporation. All references herein to the
           Company refer with equal force and effect to any corporate or other
           successor of the corporation that acquires directly or indirectly by
           merger, consolidation, purchase or otherwise, all or substantially
           all of the assets of the Company.

           (h) Injunctive Relief: The Executive agrees that the remedies
           available to the Company at law for any breach of any of these
           obligations hereunder may be inadequate, and the Executive
           accordingly agrees and consents that temporary or permanent
           injunctive relief, and/or an order of specific performance, may be
           granted in any proceeding which may be brought to enforce any
           provision hereof, without the necessity of proof of actual damage, in
           addition to any other remedies available to the Company at law.

           (i) Release: In the event Executive is terminated or Constructively
           Terminated without Cause, the obligation of the Company to make to
           Executive any or all of the payments specified under this Agreement
           (including, without limitation, the payments specified in Section IX)
           shall be subject to Executive's execution and delivery to the Company
           of

                                       19


<PAGE>


Employment Agreement Between
Corning Pharmaceutical Services, Incorporated & Christopher Kuebler
Draft #3 (Printed: 11/18/96 - 2:10 PM)
Page 20


           a release in form and substance reasonably satisfactory to the
           Company of all claims, demands, suits or actions, whether in law or
           at equity, Executive has or may have relating to or giving rise from
           such termination or Constructive Termination.


     XVIII.  Certain Additional Payments by the Company:

           (a) Anything in this Agreement to the contrary notwithstanding, in
           the event it shall be determined that any payment or distribution by,
           to or for the benefit of the Executive, whether made under this
           Agreement or otherwise (a "Payment"), would be subject to the excise
           tax imposed by Section 4999 of the Internal Revenue Code of 1986, as
           amended (the "Excise Tax"), then the Executive shall be entitled to
           receive an additional payment (a "Gross-Up Payment") in an amount
           such that after payment by the Executive of all taxes (including any
           Excise Tax) imposed upon the Gross-Up Payment, the Executive retains
           an amount of the Gross-Up Payment equal to the Excise Tax imposed
           upon the Payments.

           (b) All determinations required to be made under this Section XVIII,
           including whether a Gross-Up Payment is required and the amount of
           such Gross-Up Payment, shall be made by the accounting firm utilized
           by the Company for the preparation of its annual external financial
           statements (the "Accounting Firm") which shall provide detailed
           supporting calculations both to the Company and the Executive within
           30 days of the Event of Termination, if applicable, or such earlier
           time as is requested by the Company. The Gross-Up Payment, if any, as
           determined pursuant to this Section XVIII(b), shall be paid to the
           Executive within 10 days of the receipt of the Accounting Firm's
           determination. Any determination by the Accounting Firm shall be
           binding upon the Company and the Executive. If subsequent final
           determinations of the Excise Tax made by the Internal Revenue Service
           give rise to additional Excise Tax, then 

                                       20


<PAGE>


Employment Agreement Between
Corning Pharmaceutical Services, Incorporated & Christopher Kuebler
Draft #3 (Printed: 11/18/96 - 2:10 PM)
Page 21



           additional Gross-Up Payments shall be made by the Company to the
           Executive within 10 days after notice is received by the Company of
           such final determination.

           (c) The Executive shall notify the Company in writing of any claim by
           the Internal Revenue Service that, if successful, would require the
           payment by the Company of a Gross-Up Payment. Such notification shall
           be given as soon as practicable but no later than 10 business days
           after the Executive knows of such claim. The Executive shall not pay
           such claim prior to the expiration of the thirty-day period following
           the date on which he gives such notice to the Company (or such
           shorter period ending on the date that any payment of taxes with
           respect to such claim is due). If the Company notifies the Executive
           in writing prior to the expiration of such period that it desires to
           contest such claim, the Executive shall:


                      (i) give the Company any information reasonably requested
                      by the Company relating to such claim,

                      (ii) take such action in connection with contesting such
                      claim as the Company shall reasonably request in writing
                      from time to time, including, without limitation,
                      accepting legal representation with respect to such claim
                      by an attorney selected by the Company,

                      (iii) cooperate with the Company in good faith in order
                      effectively to contest such claim, and

                      (iv) permit the Company to participate in any proceedings
                      relating to such claim;



                                       21


<PAGE>


Employment Agreement Between
Corning Pharmaceutical Services, Incorporated & Christopher Kuebler
Draft #3 (Printed: 11/18/96 - 2:10 PM)
Page 22



           provided, however, that the Company shall bear all costs and expenses
           incurred in connection with such contest and shall indemnify and hold
           the Executive harmless, on an after-tax basis, for any Excise Tax or
           income tax imposed as a result of such contest or representation and
           payment of costs and expenses. The Company shall control all
           proceedings taken in connection with such contest. The Company may,
           at its sole option, either direct the Executive to pay the tax
           claimed and sue for a refund or contest the claim in any permissible
           manner, and the Executive agrees to prosecute such contest to a
           determination before any administrative tribunal, in a court of
           initial jurisdiction and in one or more appellate courts, as the
           Company shall determine; provided, however, that if the Company
           directs the Executive to pay such claim and sue for a refund, the
           Company shall advance the amount of such payment to the Executive on
           an interest-free basis and shall indemnify and hold the Executive
           harmless, on an after-tax basis, from any Excise Tax or income tax
           imposed with respect to such advance.


                  (d) If, after the receipt by the Executive of an amount
           advanced by the Company pursuant to subsection (c), the Executive
           becomes entitled to receive any refund with respect to such claim,
           the Executive shall promptly pay to the Company the amount of such
           refund (together with any interest paid or credited thereon after
           taxes applicable thereto). If, after the receipt by the Executive of
           an amount advanced by the Company pursuant to subsection (c), a final
           determination is made that the Executive shall not be entitled to any
           refund with respect to such claim, then such advance shall be
           forgiven and shall not be required to be repaid and the amount of
           such advance shall offset the amount of Gross-Up Payment required to
           be paid.


                                       22


<PAGE>


Employment Agreement Between
Corning Pharmaceutical Services, Incorporated & Christopher Kuebler
Draft #3 (Printed: 11/18/96 - 2:10 PM)
Page 23




     XIX.  Condition Subsequent: This Agreement shall be null and void and of no
           force or effect if the proposed spin-off of the Company from Corning
           Incorporated described in the Company's Form F10 dated September 20,
           1996 and filed with the Securities & Exchange Commission is not
           consummated.

         IN WITNESS WHEREOF, the Company has caused this Agreement to be
executed on its own behalf and has caused its corporate seal to be affixed, and
the Executive has executed this Agreement on his own behalf intending to be
legally bound, as of the date first written above.


                                            COVANCE INC.

                                    By:     ________________________________
                                            Van C. Campbell
                                            Chairman
ATTEST:

___________________________
Secretary
                                            EXECUTIVE:

                                            ________________________________
                                            Christopher Kuebler

                                       23

                              COVANCE SUBSIDIARIES

Covance Clinical and Periapproval Services Inc. (f/k/a Corning Besselaar Inc.)
    (New Jersey)
Covance Clinical Research Unit Inc. f/k/a Corning Besselaar
Clinical Research Units Inc.) (Florida)
Covance Periapproval Services Inc. (f/k/a Corning Pact Inc.) (Delaware)
Covance Clinical and Periapproval Services Limited (f/k/a Corning Besselaar
    Limited) (Ireland)
Covance AG (f/k/a GHBA AG) (Switzerland)
Covance Clinical and Periapproval
    Services AG (f/k/a Corning Besselaar AG) (Switzerland)
Covance Clinical and Periapproval Services GmbH (f/k/a G.H. Besselaar Associates
    GmbH) (Germany)
Covance Pty. Ltd. (f/k/a Corning Besselaar Pty. Ltd.) (Australia)
Covance Clinical and Periapproval Services SA (f/k/a Corning Besselaar S.A.)
    (Belgium)
Covance Clinical and Periapproval Services SARL (f/k/a Corning Besselaar SARL)
    (France)
Covance Preclinical Corporation (f/k/a Hazleton Corporation) (Washington)
Covance Laboratories GmbH (f/k/a Corning Hazleton GmbH) (Germany)
Covance Laboratories Inc. (f/k/a Corning Hazleton Inc.) (Delaware)
Covance Research Products Inc. (f/k/a HRP Inc.) (Pennsylvania)
Covance Central Laboratory Services Inc. (f/k/a Corning SciCor Inc.) (Delaware)
Covance Central Laboratory Limited Partnership d/b/a Covance Central Laboratory
    Services Inc. (f/k/a Corning SciCor Limited Partnership) (Indiana)
Covance Central Laboratories SA (f/k/a Corning SciCor S.A. (Switzerland)
Covance Ltd. (f/k/a Corning Pharmaceutical Services Ltd.) (UK)
Covance Clinical and Periapproval Services Ltd. (f/k/a Corning Besselaar Ltd.)
    (UK)
Covance Clinical Research Unit Ltd. (f/k/a Corning Besselaar CRU Ltd.) (UK)
Covance Laboratories Ltd. (f/k/a Corning Hazleton Ltd.) (UK)
Hazpen Trustees Ltd. (UK)
Corning Microtest Research Ltd. (UK)
Covance Pharmaceutical Packaging Services Inc. (f/k/a Corning National Packaging
    Inc.) (Pennsylvania)
Covance Health Economics and Outcomes Services Inc. (f/k/a Corning HTA Inc.)
    (Delaware)
Covance Biotechnology Services Inc. (f/k/a Corning Bio Inc.) (Delaware)
Covance Pharmaceutical Packaging Services AG (f/k/a CRS Pacamed AG)
    (Switzerland)
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.

<TABLE> <S> <C>

<ARTICLE>                     5             
<CIK>                         0001023131
<NAME>                         Covance Inc.     Covance Inc.
<MULTIPLIER>                          1,000           1,000
       
<S>                             <C>            <C>
<PERIOD-TYPE>                   YEAR           9-MOS
<FISCAL-YEAR-END>               DEC-31-1995     DEC-31-1996
<PERIOD-START>                   JAN-1-1995      JAN-1-1996
<PERIOD-END>                    DEC-31-1995     SEP-30-1996
<CASH>                                8,068          13,551
<SECURITIES>                              0               0
<RECEIVABLES>                        78,968          95,690
<ALLOWANCES>                              0               0
<INVENTORY>                          14,044          14,718
<CURRENT-ASSETS>                    145,783         201,981
<PP&E>                              140,708         143,956
<DEPRECIATION>                      114,748         128,713
<TOTAL-ASSETS>                      322,510         402,592
<CURRENT-LIABILITIES>               127,311         154,328
<BONDS>                                   0               0
                     0               0
                               0               0
<COMMON>                             30,816          32,368
<OTHER-SE>                           51,701          73,504
<TOTAL-LIABILITY-AND-EQUITY>        322,510         402,592
<SALES>                             409,174         357,406
<TOTAL-REVENUES>                    409,174         357,406
<CGS>                               270,726         232,828
<TOTAL-COSTS>                       361,613         308,531
<OTHER-EXPENSES>                       (784)           (212)
<LOSS-PROVISION>                          0               0
<INTEREST-EXPENSE>                    5,269           4,536
<INCOME-PRETAX>                      43,076          44,551
<INCOME-TAX>                         18,445          19,411 
<INCOME-CONTINUING>                  24,226          25,208
<DISCONTINUED>                            0               0
<EXTRAORDINARY>                           0               0
<CHANGES>                                 0               0
<NET-INCOME>                         24,226          25,208 
<EPS-PRIMARY>                             0               0
<EPS-DILUTED>                             0               0
        

</TABLE>


                              TABLE OF CONTENTS 

   
<TABLE>
<CAPTION>
                                                                               Page 
                                                                               ----- 
<S>                                                                            <C>
COVANCE INC. 
  RISK FACTORS                                                                 108 
  CAPITALIZATION OF Covance                                                    114 
  SELECTED HISTORICAL FINANCIAL DATA OF Covance                                115 
  PRO FORMA FINANCIAL INFORMATION OF Covance                                   117 
  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS 
    OF OPERATIONS OF Covance                                                   122 
  BUSINESS OF Covance                                                          129 
  MANAGEMENT OF Covance                                                        147 
  SECURITY OWNERSHIP BY CERTAIN BENEFICIAL OWNERS AND MANAGEMENT OF  Covance   158 
  DESCRIPTION OF Covance CAPITAL STOCK                                         159 
  ANTITAKEOVER EFFECTS OF CERTAIN PROVISIONS OF THE Covance CERTIFICATE OF 
    INCORPORATION AND BY-LAWS                                                  162 
  DESCRIPTION OF CERTAIN INDEBTEDNESS OF Covance                               166 
  LIABILITY AND INDEMNIFICATION OF DIRECTORS AND OFFICERS OF Covance           168 
INDEX TO FINANCIAL STATEMENTS                                                  F-1 
</TABLE>
    

<PAGE> 
   
        THE RELATIONSHIP AMONG CORNING, QUEST DIAGNOSTICS AND COVANCE 
                           AFTER THE DISTRIBUTIONS 

  After the Distributions, Quest Diagnostics Incorporated ("Quest 
Diagnostics") and Covance Inc. ("Covance") will be independent public 
companies and Corning Incorporated ("Corning") will not have any ownership 
interest in either Quest Diagnostics or Covance other than shares of Quest 
Diagnostics' voting cumulative preferred stock. Corning, Quest Diagnostics 
and Covance will enter into certain agreements, summarized below, to provide 
for an orderly transition to the status of three separate independent 
companies, to govern their relationship subsequent to the Distributions and 
to provide for the allocation of tax and certain other liabilities and 
obligations arising from periods prior to the Distributions. Copies of the 
forms of such agreements have been filed as exhibits to the Registration 
Statements of which this Information Statement is a part. The following 
description summarizes the material terms of such agreements, but is 
qualified by reference to the texts of such agreements as filed. 

Transaction Agreement 

  Corning, Quest Diagnostics and Covance will enter into the Transaction 
Agreement (the "Transaction Agreement") providing for, among other things, 
certain conditions precedent to the Distributions, certain corporate 
transactions required to effect the Distributions and other arrangements 
between Corning, Quest Diagnostics and Covance subsequent to the 
Distributions. See "The Distributions--Conditions; Termination." 

   The Transaction Agreement will provide for, among other things, 
assumptions of liabilities and cross- indemnities designed to allocate 
generally, effective as of the Distribution Date, financial responsibility 
for the liabilities arising out of or in connection with (i) the clinical 
laboratory business to Quest Diagnostics and its subsidiaries, (ii) the 
contract research business to Covance and its subsidiaries and (iii) all 
other business conducted by Corning prior to the Distribution Date to Corning 
and its subsidiaries other than Quest Diagnostics and Covance. 

   The Transaction Agreement will provide that Corning, Quest Diagnostics and 
Covance will use their respective commercially reasonable efforts to achieve 
an allocation of consolidated indebtedness of Corning and a capital structure 
that reflects the capital structure after the Distributions of Corning, Quest 
Diagnostics and Covance as contemplated in the discussion under 
"Capitalization of Quest Diagnostics" and "Capitalization of Covance." In 
addition to the specific indemnity described below, Corning, Quest 
Diagnostics and Covance are obligated under the Transaction Agreement to 
indemnify and hold harmless each other in respect of Indemnifiable Losses (as 
defined therein) arising out of or otherwise relating to the management or 
conduct of their respective businesses or the breach of any provision of the 
Transaction Agreement; provided, however, that Quest Diagnostics will have no 
obligation to indemnify or hold harmless Corning in respect of Indemnifiable 
Losses arising out of any governmental claims or investigations described in 
the next paragraph. 

   As discussed under "Business of Quest Diagnostics--Government
Investigations and Related Claims," Quest Diagnostics is subject to several
governmental investigations. Any amounts paid by Quest Diagnostics to settle
these investigations, or as a result of a judgment relating to these
investigations, will be indemnified by Corning under the Transaction Agreement.
Under the Transaction Agreement Corning will agree to indemnify Quest
Diagnostics against all monetary penalties, fines or settlements arising out of
any governmental criminal, civil or administrative investigations or claims that
have been settled prior to or are pending as of the Distribution Date, pursuant
to service of subpoena or other notice of such investigation to Quest
Diagnostics, as well as any qui tam proceeding for which a complaint was filed
prior to the Distribution Date whether or not Quest Diagnostics has been served
with such complaint or otherwise been notified of the pendency of such action,
to the extent that such investigations or claims arise out of or are related to
alleged violations of federal laws by reason of Quest Diagnostics or any company
acquired by Quest Diagnostics billing any federal program or agency for services
rendered to beneficiaries of such program or agency. Corning will also indemnify
Quest Diagnostics for 50% of the aggregate of all judgment or settlement
payments made by Quest Diagnostics that are in excess of $42.0 million in
respect of claims by private parties (i.e., nongovernmental parties such as
private insurers) that relate to indemnified or previously settled governmental
claims and that allege overbillings by Quest Diagnostics or any existing
subsidiaries of Quest Diagnostics for services provided prior to the
Distribution Date; provided, however, such indemnification for private claims
will terminate five years after the Distribution Date (whether or not settled)
and will not exceed $25.0 million in the aggregate (reduced by certain tax
benefits as described below). Quest Diagnostics' aggregate reserve with respect
to all governmental and private claims, including litigation costs, was $215
million at September 30, 1996 and is estimated to be reduced to $85 million at
the Distribution Date as a result of the payment of settled claims, primarily
the Damon Settlement of $119 million.
    

                                      28 
<PAGE> 

   
   Corning will not indemnify Quest Diagnostics against any governmental 
claims that arise after the Distribution Date, even though relating to events 
prior to the Distribution Date, or to any private claims that do not relate 
to the indemnified or previously settled governmental claims or 
investigations or investigations that relate to post- Distribution Date 
billings. Corning will not indemnify Quest Diagnostics against consequential 
or incidental damages relating to the billing claims, including losses of 
revenues and profits as a consequence of any exclusion from participation in 
federal or state health care programs or the fees and expenses of the 
litigation, including attorneys' fees and expenses. All amounts indemnified 
against by Corning for the benefit of Quest Diagnostics will be calculated on 
a net after-tax basis by taking into account any deductions and other tax 
benefits realized by Quest Diagnostics (or a consolidated group of which 
Quest Diagnostics is a member after the Distributions (the "Quest Diagnostics 
Group")) in respect of the underlying settlement, judgment payment, or other 
loss (or portion thereof) indemnified against by Corning generally at the 
time and to the extent such deductions or tax benefits are deemed to reduce 
the tax liability of Quest Diagnostics or the Quest Diagnostics Group under 
the Transaction Agreement. 

   The Transaction Agreement provides that, in the case of any claims for 
which Corning, Quest Diagnostics or Covance are entitled to indemnification, 
the indemnified party will control the defense of any claim unless the 
indemnifying party elects to assume such defense. However, in the case of all 
private claims related to indemnified governmental claims related to alleged 
overbillings, Quest Diagnostics will control the defense. Disputes under the 
Transaction Agreement are subject to binding arbitration. The Transaction 
Agreement will also provide that, except as otherwise set forth therein or in 
any other agreement, all costs or expenses incurred on or prior to the 
Distribution Date in connection with the Distributions will be allocated 
among the parties. Except as set forth in the Transaction Agreement or any 
related agreement, each party shall bear its own costs and expenses incurred 
after the Distribution Date. 

Spin-Off Tax Indemnification Agreements 

  Corning and Quest Diagnostics will enter into a tax indemnification 
agreement (the "Corning/Quest Diagnostics Spin-Off Tax Indemnification 
Agreement") pursuant to which (1) Quest Diagnostics will represent to Corning 
that, to the best of its knowledge, the materials relating to Quest 
Diagnostics submitted to the Internal Revenue Service ("IRS") in connection 
with the request for ruling submitted to the IRS are complete and accurate in 
all material respects, (2) Quest Diagnostics will represent that it has no 
present intention to undertake the transactions described in part (3)(iii) 
hereafter or cease to engage in the active conduct of providing clinical 
laboratory testing services, (3) Quest Diagnostics will covenant and agree 
that for a period of two years following the Distribution Date (the 
"Restricted Period"), (i) Quest Diagnostics will continue to engage in the 
clinical laboratory testing business, (ii) Quest Diagnostics will continue to 
manage and own at least 50% of the assets which it owns directly and 
indirectly immediately after the Distribution Date and (iii) neither Quest 
Diagnostics, nor any related corporation nor any of their respective 
directors, officers or other representatives will undertake, authorize, 
approve, recommend, permit, facilitate, or enter into any contract, or 
consummate any transaction with respect to: (A) the issuance of Quest 
Diagnostics Common Stock (including options and other instruments convertible 
into Quest Diagnostics Common Stock) which would exceed fifty percent (50%) 
of the outstanding shares of Quest Diagnostics Common Stock immediately after 
the Distribution Date; (B) the issuance of any other instrument that would 
constitute equity for federal tax purposes ("Disqualified Quest Diagnostics 
Stock"); (C) the issuance of options and other instruments convertible into 
Disqualified Quest Diagnostics Stock; (D) any repurchases of Quest 
Diagnostics Common Stock, unless such repurchases satisfy certain 
requirements; (E) the dissolution, merger, or complete or partial liquidation 
of Quest Diagnostics or any announcement of such action; or (F) the waiver, 
amendment, termination or modification of any provision of the Quest 
Diagnostics Rights Plan (as defined therein) in connection with, or in order 
to permit or facilitate, any acquisition of Quest Diagnostics Common Stock or 
other equity interest in Quest Diagnostics, and (4) Quest Diagnostics will 
agree to indemnify Corning for Taxes (as defined below) arising from 
violations of (1), (2) or (3) above and for Taxes arising as a result of (A) 
an acquisition of 20% or more of the stock of Quest Diagnostics by a person 
or related persons during the Restricted Period or (B) the commencement of a 
tender or purchase offer by a third party for 20% or more of Quest 
Diagnostics stock. If obligations of Quest Diagnostics under this agreement 
were breached and as a result thereof one or both of the Distributions do not 
qualify for the treatment stated in the ruling Corning requested from the IRS 
(the "IRS Ruling"), Quest Diagnostics would be required to indemnify Corning 
for Taxes imposed and such indemnification obligations could exceed the net 
asset value of Quest Diagnostics at such time. 
    

   Corning and Covance will enter into a tax indemnification agreement (the 
"Corning/Covance Spin-Off Tax Indemnification Agreement") pursuant to which 
(1) Covance will represent to Corning that to the best of its knowledge, 

                                      29 
<PAGE> 

   
the materials relating to Covance submitted to the IRS in connection with the 
request for ruling submitted to the IRS are complete and accurate in all 
material respects, (2) Covance will represent that it has no present 
intention to undertake the transactions described in part (3)(iii) hereafter 
or to cease to engage in the active conduct of providing contract research 
services, (3) Covance will covenant and agree that during the Restricted 
Period, (i) Covance will continue to engage in the contract research 
business, (ii) Covance will continue to manage and own at least 50% of the 
assets which it owns directly and indirectly immediately after the 
Distribution Date and (iii) neither Covance, nor any related corporations nor 
any of their respective directors, officers or other representatives will 
undertake, authorize, approve, recommend, permit, facilitate, or enter into 
any contract, or consummate any transaction with respect to: (A) the issuance 
of Covance Common Stock (including options and other instruments convertible 
into Covance Common Stock) which would exceed fifty percent (50%) of the 
outstanding shares of Covance Common Stock immediately after the Distribution 
Date; (B) the issuance of any other instrument that would constitute equity 
for federal tax purposes ("Disqualified Covance Stock"); (C) the issuance of 
options and other instruments convertible into Disqualified Covance Stock; 
(D) any repurchases of Covance Common Stock, unless such repurchases satisfy 
certain requirements; (E) the dissolution, merger, or complete or partial 
liquidation of Covance or any announcement of such action; or (F) the waiver, 
amendment, termination or modification of any provision of the Covance Rights 
Plan (as defined therein) in connection with, or in order to permit or 
facilitate, any acquisition of Covance Common Stock or other equity interest 
in Covance and (4) Covance will agree to indemnify Corning for Taxes arising 
from violations of (1), (2) or (3) above and for Taxes arising as a result of 
(A) an acquisition of 20% or more of the stock of Covance by a person or 
related persons during the Restricted Period or (B) the commencement of a 
tender or purchase offer by a third party for 20% or more of Covance stock. 
If obligations of Covance under this agreement were breached and as a result 
thereof one or both of the Distributions do not qualify for the treatment 
stated in the IRS Ruling, Covance would be required to indemnify Corning for 
Taxes imposed and such indemnification obligations could exceed the net asset 
value of Covance at such time. 

   Quest Diagnostics and Covance will enter into a tax indemnification 
agreement (the "Quest Diagnostics/ Covance Spin-Off Tax Indemnification 
Agreement") which will be essentially the same as the Corning/Covance 
Spin-Off Tax Indemnification Agreement except that Covance will make 
representations to and indemnify Quest Diagnostics as opposed to Corning. If 
obligations of Covance under this agreement were breached and as a result 
thereof one or both of the Distributions do not qualify for the treatment 
stated in the IRS Ruling, Covance would be required to indemnify Quest 
Diagnostics for Taxes imposed and such indemnification obligations could 
exceed the net asset value of Covance at such time. Quest Diagnostics and 
Covance will enter into a second tax indemnification agreement (the 
"Covance/Quest Diagnostics Spin-Off Tax Indemnification Agreement") which 
will be essentially the same as the Corning/Quest Diagnostics Spin-Off Tax 
Indemnification Agreement except that Quest Diagnostics will make 
representations to and indemnify Covance as opposed to Corning. If 
obligations of Quest Diagnostics under this agreement were breached and as a 
result thereof one or both of the Distributions do not qualify for the 
treatment stated in the IRS Ruling, Quest Diagnostics would be required to 
indemnify Covance for Taxes imposed and such indemnification obligations 
could exceed the net asset value of Quest Diagnostics at such time. 

   The Spin-Off Tax Indemnification Agreements will also require (i) Quest 
Diagnostics to take such actions as Corning may reasonably request and (ii) 
Covance to take such actions as Corning and Quest Diagnostics may reasonably 
request to preserve the favorable tax treatment provided for in any rulings 
obtained from the IRS in respect of the Distributions. 

Tax Sharing Agreement 

  Corning, Quest Diagnostics and Covance will enter into a tax sharing 
agreement (the "Tax Sharing Agreement") which will allocate responsibility 
for federal income and various other taxes ("Taxes") among the three 
companies. The Tax Sharing Agreement provides that, except for Taxes arising 
as a result of the failure of either or both of the Distributions to qualify 
for the treatment stated in the IRS Ruling (which Taxes are allocated either 
pursuant to the Spin-Off Tax Indemnification Agreements or as described 
below), Corning is liable for and will pay the federal income taxes of the 
consolidated group that includes Quest Diagnostics and Covance and their 
subsidiaries, provided, however, that Quest Diagnostics and Covance are 
required to reimburse Corning for taxes for periods beginning after December 
31, 1995 in which they are members of the Corning consolidated group and for 
which tax returns have not been filed as of the Distribution Date. This 
reimbursement obligation is based on the hypothetical separate federal tax 
liability of Quest Diagnostics and Covance, including their respective 
subsidiaries, calculated on a separate consolidated basis, subject to certain 
adjustments. Under the Tax Sharing Agreement, in the case of adjustments by a 
taxing authority of a 
    

                                      30 
<PAGE> 

   
consolidated federal income tax or certain other tax returns prepared by 
Corning which includes Quest Diagnostics or Covance, then, subject to certain 
exceptions, Corning is liable for and will pay any tax assessments, and is 
entitled to any tax refunds, resulting from such audit. 

   The Tax Sharing Agreement further provides that, if either of the 
Distributions fails to qualify for the tax treatment stated in the IRS Ruling 
(for reasons other than those indemnified against under one or more of the 
Spin-Off Tax Indemnification Agreements), Taxes imposed upon or incurred by 
Corning, Quest Diagnostics or Covance as a result of such failure are to be 
allocated among Corning, Quest Diagnostics and Covance in such a manner as 
will take into account the extent to which the actions or inactions of each 
may have contributed to such failure, and Corning, Quest Diagnostics and 
Covance each will indemnify and hold harmless the other from and against the 
taxes so allocated. If it is determined that none of the companies 
contributed to the failure of such distribution to qualify for the tax 
treatment stated in the IRS Ruling, the liability for taxes will be borne by 
each in proportion to its relative average market capitalization as 
determined by the average closing price for the common stock of each during 
the 20 trading-day period immediately following the Distribution Date. In the 
event that either of the Distributions fails to qualify for the tax treatment 
stated in the IRS Ruling and the liability for taxes as a result of such 
failure is allocated among Corning, Quest Diagnostics and Covance, the 
liability so allocated to Quest Diagnostics or Covance could exceed the net 
asset value of Quest Diagnostics or Covance, respectively. 

Voting Cumulative Preferred Stock of Quest Diagnostics 

  After the Distributions, Corning will retain 1,000 shares of Quest 
Diagnostics' voting cumulative preferred stock, with an aggregate liquidation 
preference of $1.0 million. Corning is the sole holder of such shares. For a 
description of the terms of the Quest Diagnostics voting cumulative preferred 
stock, see "Description of Quest Diagnostics Capital Stock--Voting Cumulative 
Preferred Stock." 
    

                                      31 
<PAGE> 

                                 COVANCE INC. 

                                 RISK FACTORS 

  Corning shareholders should be aware that the Distributions and ownership of 
the Covance Common Stock involve certain risks, including those described 
below, which could adversely affect the value of their holdings. Neither 
Corning nor Covance makes, nor is any other person authorized to make, any 
representations as to the future market value of Covance Common Stock. 

Risks Relating to the Distributions 
   
  Effects on Corning Stock. Following the Distributions, Corning Common Stock 
will continue to be listed and traded on the NYSE and certain other stock 
exchanges. As a result of the Distributions, the trading price of Corning 
Common Stock is expected to be correspondingly lower than the trading price 
of Corning Common Stock immediately prior to the Distributions. There can be 
no assurance that the combined trading prices of Corning Common Stock, Quest 
Diagnostics Common Stock and Covance Common Stock after the Distributions 
will be equal to or greater than the trading price of Corning Common Stock 
prior to the Distributions. 
    
Risks Relating to Covance 
   
  Financial Impact of the Distributions on Covance. While Covance has a 
substantial operating history, it has not operated as a separate independent 
company. As a Corning subsidiary, Covance has had access to the cash flow 
generated by Corning and to Corning's credit, which is based on the combined 
assets of Corning, which included Quest Diagnostics and Covance. Subsequent 
to the Distributions, Covance will not have the benefit of Corning's cash 
flow or assets. This may impact, among other things, Covance's ability to 
expand, through acquisitions or otherwise, and could thereby have an adverse 
effect on Covance's operating earnings and cash flow. 
    
   Dependence on and Effect of Government Regulation. Covance's business 
depends on the continued strict government regulation of the drug development 
process, especially in the United States and Europe. Changes in regulation, 
including a relaxation in regulatory requirements or the introduction of 
simplified drug approval procedures, could have a material adverse effect on 
the demand for the services offered by Covance. 

   The failure on the part of Covance to comply with applicable regulations 
could result in the termination of ongoing research or the disqualification 
of data for submission to regulatory authorities. Furthermore, the issuance 
of a notice of finding by the Food and Drug Administration (the "FDA") to 
either Covance or its clients based upon a material violation by Covance of 
Good Clinical Practices ("GCP"), Good Laboratory Practices ("GLP") or Current 
Good Manufacturing Practices ("GMP") requirements could have a material 
adverse effect on Covance. See "Business of Covance--CRO Industry Overview" 
and "Business of Covance--Government Regulation." 

   Fixed Price Nature of Contracts; Loss or Delay of Large Contracts. Most of 
Covance's contracts for the provision of its services are fixed price or 
fee-for-service with a cap. Approximately 75% of Covance's net revenues are 
earned under contracts which generally range in duration from a few months to 
two years. For the fiscal year ended 1995, fixed price and fee-for-service 
contracts with a cap accounted for 65% of contract generated net revenues, 
with fixed price accounting for 40% and fee-for-service with a cap accounting 
for 25% of contract generated net revenues. The balance of the net revenues 
generated under contracts in 1995 were pursuant to fee- for-service contracts 
without a cap. Since Covance's contracts are predominantly structured as 
fixed price or fee- for-service with a cap, Covance bears the risks of cost 
overruns. Underpricing of such contracts or significant cost overruns could 
have a material adverse effect on Covance. 

   Most of Covance's contracts for the provision of its services, including 
contracts with governmental agencies, are terminable by the client 
immediately or upon notice. Contracts may be terminated for a variety of 
reasons, including the failure of products to satisfy safety requirements, 
unexpected or undesired results of the product, the client's decision to 
terminate the development of the product or to forego or end a particular 
study, insufficient patient enrollment or investigator recruitment or 
Covance's failure to properly discharge its obligations thereunder. Although 
the contracts often require payment to Covance of expenses to wind down the 
study and fees earned to date and, in some cases, a termination fee or a 
payment of a portion of the fees or profits that would have been earned under 
the contract if the contract had not been terminated early, the loss of a 
large contract or the loss of 

                                     108 
<PAGE> 

multiple contracts could have a material adverse effect on Covance. See 
"Business of Covance--Contractual Arrangements." 

   Biomanufacturing--New Business Venture. Covance holds a majority interest 
in Covance Biotechnology Services Inc. ("Covance Biotechnology," formerly 
known as Corning Bio Inc.), a majority owned company formed in 1995 to 
manufacture peptides and recombinant proteins for biotechnology and 
pharmaceutical clients in accordance with GMP for preclinical and clinical 
trials as well as for commercial sales and to provide process development 
services. See "Business of Covance--Services--Biomanufacturing." Outsourced 
biomanufacturing is a relatively new industry and as such companies in this 
industry are subject to all of the risks inherent in a new or emerging 
industry, including changes in the regulatory regime, an absence of an 
established earnings history, the availability of adequately trained 
management and employees, and the potential for significant client 
concentration. As a start-up venture, Covance Biotechnology is subject to the 
risks inherent in the establishment of a new business enterprise, including, 
among others, unanticipated construction delays, operational and 
manufacturing problems, additional and unforeseen costs and expenses and 
inability to attract and retain clients. There can be no assurance that, even 
after the expenditure of substantial funds and efforts, Covance Biotechnology 
will be able to market successfully its biomanufacturing services. Covance 
Biotechnology's biomanufacturing facility is still under construction and is 
expected to be "mechanically" completed during the fourth quarter of 1996. 
Mechanical completion occurs when all structural aspects of the facility are 
complete, all mechanical equipment and systems are installed and a 
certificate of occupancy has been issued by an applicable governmental 
authority. After mechanical completion, the facility must be "validated," 
which means that the various equipment, systems and procedures that are 
required to manufacture a biologic must be thoroughly tested and reviewed. 
Although Covance Biotechnology has submitted proposals to a number of 
prospective biopharmaceutical clients, it has been awarded only one contract, 
but has signed a number of letters of intent for the provision of services. 
For the period ended December 31, 1995, Covance Biotechnology reported a net 
loss of approximately $1.9 million, and for the nine months ended September 
30, 1996, Covance Biotechnology reported a net loss of approximately $2.3 
million. 

   The biomanufacturing facility is being financed through several tax 
retention operating leases provided by a commercial lending institution (the 
"Bank") and, during the construction phase, is being leased by a general 
contractor (the "General Contractor"). The leases expire 10 years from the 
date of mechanical completion of the facility. The annual minimum lease 
payments are currently estimated at $5.5 million. At the expiration of the 
lease term, Covance Biotechnology is liable for the unamortized balance of 
the cost of the facility, currently estimated to be $37 million. Covance 
Biotechnology may also choose to purchase the facility at specific dates over 
the 10 year period. Using current estimates, the purchase price would be 
approximately $54 million at the end of the first year, decreasing on an 
amortizing basis to approximately $37 million at the end of the tenth year. 

   Volatility of Quarterly Operating Results. Covance's quarterly operating 
results are subject to volatility due to such factors as the commencement, 
completion or cancellation of large contracts, progress of ongoing contracts, 
acquisitions, the timing of start-up expenses for new offices and changes in 
the mix of services. Since a large percentage of Covance's operating costs 
are relatively fixed, variations in the timing and progress of large 
contracts can materially affect quarterly results. Because a significant 
portion of Covance's revenues are generated by its international operations, 
exchange rate fluctuations may also influence these results. Covance believes 
that comparisons of its quarterly financial results are not necessarily 
meaningful and should not be relied upon as an indication of future 
performance. However, fluctuations in quarterly results could affect the 
market price of the Covance Common Stock in a manner unrelated to the longer 
term operating performance of Covance. See "Management's Discussion and 
Analysis of Financial Condition and Results of Operations of 
Covance--Quarterly Results." 

   Dependence on Certain Industries and Clients. Revenues of Covance are 
highly dependent on research and development expenditures by the 
pharmaceutical and biotechnology industries. Accordingly, Covance's 
operations could be materially and adversely affected by general economic 
downturns in these industries, the impact of the current trend toward 
consolidation in these industries or other factors resulting in a decrease in 
research and development expenditures. Furthermore, Covance has benefitted to 
date from the increasing tendency of pharmaceutical and biotechnology 
companies to outsource both small and large clinical research projects. A 
reversal of this trend could have a material adverse effect on the revenues 
of Covance. 

   Covance believes that concentrations of business in the contract research 
organization ("CRO") industry are not uncommon. Covance has experienced such 
concentration in the past and may experience such concentration in fiscal 
1997 and in future years. No client accounted for 10% or more of Covance's 
net revenues in 1993, 1994 or 1995. None 

                                     109 
<PAGE> 

of Covance's clients accounted for greater than 5% of Covance's net revenues 
in the year ended December 31, 1993. In the years ended December 31, 1994 and 
1995, one client accounted for greater than 5% of Covance's net revenue. In 
fiscal 1993, 1994 and 1995 and the nine months ended September 30, 1996, 
Covance's top five clients accounted for approximately 17%, 20%, 21% and 21%, 
respectively, of Covance's net revenue. The loss of business from a 
significant client or group of clients could have a material adverse effect 
on Covance. See "Business of Covance--Trends Affecting the CRO Industry" and 
"Business of Covance--Clients and Marketing." 

   Competition; CRO Industry Consolidation; Few Barriers to Entry. The CRO 
industry is highly fragmented, with participants ranging from hundreds of 
small, limited-service providers to a few full service CROs with global 
operations. Covance primarily competes against in-house departments of 
pharmaceutical companies, full-service CROs and, to a lesser extent, 
universities and teaching hospitals. CROs compete on the basis of several 
factors, including reputation for on-time quality performance, expertise and 
experience in specific therapeutic areas, scope of service offerings, how 
well such services are integrated, strengths in various geographic markets, 
price, technological expertise and efficient drug development processes, the 
ability to acquire, process, analyze and report data in a time- saving 
accurate manner, the ability to manage large-scale clinical trials both 
domestically and internationally, expertise and experience in health 
economics and size. While Covance has competed effectively in these areas, 
there can be no assurance that Covance will be able to continue to do so. As 
a result of competitive pressures, the CRO industry is consolidating. This 
trend is likely to produce competition among the larger CROs for both clients 
and acquisition candidates and companies may choose to limit the CROs they 
are willing to work with. In addition, there are few barriers to entry for 
small, limited-service entities considering entering the CRO industry. These 
entities may compete against larger CROs for clients. Furthermore, the CRO 
industry has attracted the attention of the investment community, which could 
lead to increased competition by increasing the availability of financial 
resources for CROs. Increased competition may lead to price and other forms 
of competition that could have a material adverse effect on the results of 
operations of Covance. See "Business of Covance--Competition." 
   
   Potential Liability. In connection with many clinical trials, Covance 
contracts with physicians, also referred to as investigators, to conduct the 
clinical trials to test new drugs on human volunteers. Such testing creates 
risk of liability for personal injury or death to volunteers, particularly to 
volunteers with life-threatening illnesses, resulting from adverse reactions 
to the drugs administered. Although Covance does not believe it is legally 
accountable for the medical care rendered by third-party investigators, it is 
possible that Covance could be held liable for the claims and expenses 
arising from any professional malpractice of the investigators with which it 
contracts or in the event of personal injury or death of persons 
participating in clinical trials. Covance also could be held liable for 
errors or omissions in connection with the services it performs that result 
in harm that arises either during or after a trial to study volunteers or 
consumers of the drug in the general marketplace subsequent to regulatory 
approval of the drug. For instance, improper storage, packaging or 
manufacturing of a compound could lead to its adulteration. In addition, 
Covance could be liable for the general risks associated with its Phase I 
facility including, but not limited to, adverse events resulting from the 
administration of drugs to clinical trial participants or the professional 
malpractice of Phase I medical care providers. Further, Covance could be held 
liable for harm to study volunteers or consumers of an approved drug for 
testing errors or omissions by either its preclinical or central 
laboratories. Moreover, because Covance's preclinical laboratories also 
conduct tests for the agrochemical and food industries, Covance could be held 
liable for errors or omissions that result in unsafe products entering the 
marketplace. Finally, although Covance's animal breeding facilities maintain 
procedures in accordance with applicable government regulations and the 
preventive measures contained in its company policies for the quarantine and 
handling of imported animals, including primates, there is a risk that these 
animals may be infected with diseases that may be harmful and even lethal to 
themselves and humans. In such a case, Covance may be subject to claims by 
employees, or persons who come in contact with employees, who were exposed to 
such infectious diseases. In 1996 Covance, with the approval of the Texas 
Department of Health and the Centers for Disease Control, destroyed a 
shipment of monkeys from the Philippines because some had been infected with 
a substrain of the Ebola- Reston virus, which is lethal to monkeys. Covance 
does not believe that it will have any liability resulting from such incident 
because all of Covance's employees who may have had any exposure to the 
monkeys who may have been infected by the virus were carefully monitored and 
have shown no sign of unexplained illness. 
    
   Covance believes that its risks are generally reduced by contractual 
indemnification provisions with clients and, where applicable, investigators 
(the scope of which varies from client to client and the performance of which 
are not secured); insurance maintained by clients and, where applicable, 
investigators and by Covance; and various regulatory requirements, including 
the use of institutional review boards in the clinical area and the 
procurement 

                                     110 
<PAGE> 

of each volunteer's informed consent to participate in the clinical study. 
The contractual indemnifications generally do not protect Covance against 
liability arising from certain of its own actions such as negligence. Covance 
could be materially and adversely affected if it were required to pay damages 
or bear the costs of defending any claim outside the scope of or in excess of 
a contractual indemnification provision or beyond the level of insurance 
coverage or in the event that an indemnifying party does not fulfill its 
indemnification obligations. There can be no assurance that Covance will be 
able to maintain such insurance coverage on terms acceptable to Covance. 

   Risks Associated with Acquisitions; Integration of Acquired 
Operations. During the last three fiscal years Covance completed three 
acquisitions. Covance reviews many acquisition candidates in the ordinary 
course of business and, in addition to acquisitions already made, Covance is 
continually evaluating new acquisition opportunities. Acquisitions involve 
numerous risks, including, among other things, difficulties and expenses 
incurred in connection with the acquisitions and the subsequent assimilation 
of the operations and services or products of the acquired companies, the 
diversion of management's attention from other business concerns and the 
potential loss of key employees of the acquired company. Acquisitions of 
foreign companies also may involve the additional risks of assimilating 
differences in foreign business practices and overcoming language and other 
cultural barriers. In the event that the operations of an acquired business 
do not perform as expected, Covance may be required to restructure the 
acquired business or write off the value of some or all of the assets of the 
acquired business. Further, to the extent that any future acquisitions are 
effected through the issuance of stock to the shareholders of the acquired 
company, the interest of shareholders holding shares of Covance prior to the 
acquisition could be diluted. There can be no assurance that acquisition 
candidates will be available on terms and conditions acceptable to Covance 
or, despite Covance's success with prior acquisitions, that any past or 
future acquisition will be successfully integrated into Covance's operations, 
or that they will contribute favorably to Covance's results of operations or 
financial condition. See "Management's Discussion and Analysis of Financial 
Condition and Results of Operations of Covance." 

   Potential Adverse Impact of Health Care Reform. The health care industry 
is subject to changing political, economic and regulatory influences that may 
affect the pharmaceutical and biotechnology industries. During 1994, several 
comprehensive health care reform proposals were introduced in Congress. The 
intent of the proposals was, generally, to expand health care coverage for 
the uninsured and reduce the growth of total health care expenditures. While 
none of the proposals was adopted, health care reform may again be addressed 
by Congress, and there have been efforts recently to enact less comprehensive 
reform bills. Similar reform movements have occurred in Europe and Asia. 
Implementation of government health care reform may adversely affect research 
and development expenditures by pharmaceutical and biotechnology companies 
which could decrease the business opportunities available to Covance in the 
United States and abroad. Covance is unable to predict the likelihood of such 
or similar legislation being enacted into law or the effects such legislation 
would have on Covance. 

   Loss of Brand Names. In connection with the Covance Spin-Off Distribution, 
Covance will change the trade names under which it conducts its business. 
Covance believes that its business has benefitted from the use of the 
"Corning," "Besselaar," "SciCor," "Hazleton," "PACT," "HTA," "National 
Packaging," "CRS Pacamed" and "HRP" brand names. The impact of the change in 
trade names on Covance's business and operations cannot be fully predicted. 
   
   Absence of Dividends; Restrictions on Dividends Imposed by the Covance 
Credit Facility. It is currently contemplated that, following the 
Distributions, Covance will not pay cash dividends in the foreseeable future, 
but will retain earnings to provide funds for the operation and expansion of 
its business. In addition, other than with respect to stock dividends, and 
certain purchases, repurchases or other distributions made pursuant to the 
Benefits Plans and the Rights Plan (each as defined in the Covance Credit 
Facility) the Covance Credit Facility prohibits Covance from paying cash 
dividends on the Covance Common Stock during a Default or an Event of 
Default, or if after giving effect to the payment of such dividends Covance 
would not be in compliance with the financial covenants contained therein. 
See "Description of Capital Stock of Covance--Covance Common Stock--Dividend 
Policy," "Management's Discussion and Analysis of Financial Condition and 
Results of Operations of Covance-- Liquidity and Capital Resources" and 
"Description of Certain Indebtedness of Covance." 

   Potential Liability under the Spin-Off Tax Indemnification 
Agreements. Covance will enter into the Corning/ Covance Spin-Off Tax 
Indemnification Agreement that will prohibit Covance for a period of two 
years after the Distribution Date from taking certain actions, including a 
sale of 50% or more of the assets of Covance or engaging in certain equity or 
financing transactions, that might jeopardize the favorable tax treatment of 
the Distributions under Code section 355 and will provide Corning with 
certain rights of indemnification against Covance. Covance 
    
                                     111 
<PAGE> 
   
may also have indemnification obligations under the Spin-Off Tax 
Indemnification Agreements in the case of the acquisition of, or tender or 
purchase offer by another person for, 20% or more of the outstanding Covance 
Common Stock. The Corning/Covance Spin-Off Tax Indemnification Agreement will 
also require Covance to take such actions as Corning may reasonably request 
to preserve the favorable tax treatment provided for in any rulings obtained 
from the IRS in respect of the Distributions. Covance will also enter into 
the Quest Diagnostics/Covance Spin-Off Tax Indemnification Agreement that 
will prohibit Covance for a period of two years after the Distribution Date 
from taking certain actions, including a sale of 50% or more of the assets of 
Covance or engaging in certain equity or financing transactions, that might 
jeopardize the favorable tax treatment of the Covance Spin-Off Distribution 
under Code section 355 and will provide Quest Diagnostics with certain rights 
of indemnification against Covance. The Quest Diagnostics/Covance Spin-Off 
Tax Indemnification Agreement will also require Covance to take such actions 
as Quest Diagnostics may reasonably request to preserve the favorable tax 
treatment provided for in any rulings obtained from the IRS in respect of the 
Distributions. If obligations of Covance under either the Corning/Covance 
Spin-Off Tax Indemnification Agreement or the Quest Diagnostics/Covance 
Spin-Off Tax Indemnification Agreement were breached and primarily as a 
result thereof either of the Distributions do not receive favorable tax 
treatment under Code section 355, Covance would be required to indemnify 
Corning and Quest Diagnostics for Taxes imposed and such indemnification 
obligations could exceed the net asset value of Covance at such time. See 
"The Relationship Among Corning, Quest Diagnostics and Covance After the 
Distributions-- Spin-Off Tax Indemnification Agreements." 
    
   Potential Adverse Effect of Exchange Rate Fluctuations on 
Results. Approximately 22%, 24% and 30% of Covance's net revenues for the 
years ended December 31, 1993, 1994, and 1995, respectively, were derived 
from Covance's operations outside of the United States. Contracts between 
Covance's foreign subsidiaries and its clients are frequently denominated in 
currencies other than the applicable subsidiary's local currency. 
Accordingly, payments received for services rendered under such contracts are 
denominated in a currency different than the currency used for the payment of 
the subsidiary's expenses. Therefore, the subsidiary's net revenues, expenses 
and earnings are affected by fluctuations in exchange rates. To the extent 
Covance is unable to shift to its clients the effects of currency 
fluctuations, these fluctuations could have a material adverse effect on 
Covance's results of operations. Covance does not currently hedge against the 
risk of exchange rate fluctuations. In addition, Covance's combined financial 
statements are denominated in U.S. dollars, and, accordingly, changes in 
exchange rates between the applicable foreign currency and the U.S. dollar 
will affect the translation of such subsidiary's financial results into U.S. 
dollars for purposes of reporting Covance's combined financial results. 

   Absence of a Prior Public Market. Prior to the Distributions, there has 
been no public market for the Covance Common Stock. Although it is expected 
that the Covance Common Stock will be approved for listing on the NYSE, there 
is no existing market for the Covance Common Stock and there can be no 
assurance as to the liquidity of any markets that may develop, the ability of 
Covance stockholders to sell their shares of Covance Common Stock or at what 
price Covance stockholders will be able to sell their shares of Covance 
Common Stock. Future trading prices will depend on many factors including, 
among other things, prevailing interest rates, Covance's operating results 
and the market for similar securities. 

   Potential Volatility of Stock Price. The market price of Covance Common 
Stock could be subject to wide fluctuations in response to quarter-to-quarter 
variations in operating results, changes in earnings estimates by analysts, 
market conditions in the contract research industry, prospects for health 
care reform, changes in government regulation and general economic 
conditions. In addition, the stock market has from time to time experienced 
significant price and volume fluctuations that have been unrelated to the 
operating performance of particular companies. Moreover, Covance Common Stock 
could be subject to wide fluctuations for some time after the Distributions 
as a result of heavy trading volume stemming from sales by shareholders of 
Corning Common Stock who decide not to continue owning Covance Common Stock. 
Certain of such sales may include those to be made on behalf of investment 
plans maintained for the benefit of Corning employees. These plans currently 
hold slightly less than 5% of the outstanding Corning Common Stock and, as a 
result of the Distributions, are expected to hold a similar percentage of the 
Covance Common Stock. From time to time as market conditions warrant, and as 
the administrator of the plans believes to be in the best interests of the 
employee beneficiaries, the administrator will sell all of the Covance Common 
Stock held by the plans. Such sales are expected to occur within a period of 
three years after the Distribution Date. See "Security Ownership by Certain 
Beneficial Owners and Management of Covance." These market fluctuations could 
have an adverse effect on the market price of Covance Common Stock. Covance 
stockholders should be aware, and must be willing to bear the risk, of such 
fluctuations in earnings and stock price. 

                                     112 
<PAGE> 

   Dependence on Key Employees. Covance's affairs are managed by a small 
number of key management personnel, the loss of any of whom could have an 
adverse impact on Covance. Covance has separation agreements with such 
persons. There can be no assurance that Covance can retain its key managerial 
and technical employees or that it can attract, assimilate or retain other 
skilled technical personnel in the future. See "Management of Covance." 

   
   Certain Antitakeover Effects. Covance's amended and restated certificate 
of incorporation (the "Covance Certificate") and by-laws (the "Covance 
By-Laws"), and the Delaware General Corporation Law ("DGCL"), contain several 
provisions that could have the effect of delaying, deferring or preventing a 
change in control of Covance in a transaction not approved by the board of 
directors of Covance (the "Covance Board"), or, in certain circumstances, by 
the disinterested members of the Covance Board. In addition, an acquisition 
of certain securities or assets of Covance within two years after the 
Distribution Date might jeopardize the tax treatment of the Distributions and 
could result in Covance being required to indemnify Corning and Quest 
Diagnostics. See "-- Potential Liability under the Spin-Off Tax 
Indemnification Agreements" and "Antitakeover Effects of Certain Provisions 
of the Covance Certificate of Incorporation and the Covance By-Laws." 
    

                                     113 
<PAGE> 

                          CAPITALIZATION OF COVANCE 

  The following table sets forth Covance's capitalization as of September 30, 
1996 giving effect to the estimated initial borrowing under the Covance 
Credit Facility and the Covance Spin-Off Distribution as if such transactions 
occurred on such date. This table should be read in conjunction with the 
Covance Financial Statements (as defined below) and notes thereto, and the 
Covance Pro Forma Financial Information (as defined below) and notes thereto 
included elsewhere herein. Historical and pro forma capitalization may not be 
indicative of Covance's future capitalization as an independent company. See 
"Management's Discussion and Analysis of Financial Condition and Results of 
Operations of Covance" and "Business of Covance." 

                                                       Pro Forma 
                                        Historical    Adjustments     Pro Forma 
                                        ----------    ------------   -----------
                                                     (in thousands) 
Long-Term Debt: 
 Due to banks                            $             $ 128,165 (a)   $128,165 
 Due to Corning and affiliates            118,165       (118,165)(a) 
                                          --------     -----------     ---------
  Total Long-Term Debt                    118,165         10,000        128,165 
                                          --------     -----------     ---------
Stockholder's Equity: 
 Contributed capital                       32,368         22,500 (b)     54,868 
 Retained earnings                         70,505        (17,822)(b)     52,683 
 Cumulative translation adjustment          2,999                         2,999 
                                          --------     -----------     ---------
  Total Stockholder's Equity              105,872          4,678        110,550 
                                          --------     -----------     ---------
Total Capitalization                     $224,037      $  14,678       $238,715 
                                          ========     ===========     =========

- ------------- 

(a) The pro forma adjustment to long-term debt due to banks and due to 
    Corning and affiliates reflect the borrowings to be incurred in 
    connection with the Covance Spin-Off Distribution. Immediately prior to 
    the Covance Spin-Off Distribution, Covance will incur long-term bank 
    borrowings to repay Corning and affiliates for all intercompany 
    borrowings and income tax liabilities. Assuming the Covance Spin-Off 
    Distribution occurred on September 30, 1996, such borrowings would 
    aggregate approximately $128.2 million. The assumed interest rate on 
    these borrowings is 6.0%. 

(b) The pro forma adjustments to contributed capital and retained earnings 
    represent costs directly related to the Covance Spin-Off Distribution 
    expected to be incurred during the fourth quarter of 1996. Such costs 
    consist of direct costs of the Covance Spin-Off Distribution and one-time 
    charges associated with shares allocated to the employee stock ownership 
    and other employee benefit plans. 

                                     114 
<PAGE> 

                        SELECTED HISTORICAL FINANCIAL 
                               DATA OF COVANCE 

  The following table presents selected historical financial data of Covance 
at the dates and for each of the periods indicated. The selected financial 
data as of and for each of the years ended December 31, 1995, 1994 and 1993 
have been derived from the audited combined financial statements of Covance 
(the "Audited Covance Financial Statements") and the notes thereto included 
elsewhere herein. The selected financial data as of and for the nine months 
ended September 30, 1996 and 1995 and the years ended December 31, 1992 and 
1991 have been derived from the unaudited combined financial statements of 
Covance (the "Covance Interim Financial Statements" and, together with the 
Audited Covance Financial Statements, the "Covance Financial Statements"). In 
the opinion of management, the unaudited combined financial statements 
include all adjustments, consisting of normal recurring accruals, that are 
necessary for a fair presentation of the financial position and results of 
operations for these periods. The unaudited interim results of operations for 
the nine months ended September 30, 1996 are not necessarily indicative of 
the results for the entire year ending December 31, 1996. 

  The selected financial data should be read in conjunction with the Covance 
Financial Statements and notes thereto, and the Covance Pro Forma Financial 
Information included elsewhere herein. Historical combined financial data may 
not be indicative of Covance's future performance as an independent company. 
See the Covance Financial Statements and notes thereto and Covance Pro Forma 
Financial Information and notes thereto. See also "Management's Discussion 
and Analysis of Financial Condition and Results of Operations of Covance" and 
"Business of Covance." 

                                     115 
<PAGE> 
<TABLE>
<CAPTION>

                                     Nine Months Ended 
                                       September 30,                          Year Ended December 31, 
                                  ----------------------     ----------------------------------------------------------- 
                                    1996         1995          1995         1994        1993        1992        1991 
                                  --------     ----------    ----------   --------    --------    --------   ---------- 
                                                                      (in thousands) 
<C>                               <C>          <C>           <C>          <C>         <C>         <C>         <C>      
Income Statement Data: 
Net revenues                      $357,406     $302,886      $409,174     $319,501    $289,697    $270,871    $246,949 
Costs and expenses: 
 Cost of revenue                   232,828      198,820       270,726      213,490     192,783     192,375     176,860 
 Selling, general and 
   administrative                   57,573       46,965        64,201       48,892      42,949      41,230      37,106 
 Restructuring charge                             4,616         4,616                                3,373 
 Depreciation and 
   amortization                     18,130       16,166        22,070       18,520      16,984      15,212      14,621 
                                     ------      --------      --------      ------     ------      ------     -------- 
   Total                           308,531      266,567       361,613      280,902     252,716     252,190     228,587 
                                     ------      --------      --------      ------     ------      ------     -------- 
Income from operations              48,875       36,319(a)     47,561(a)    38,599      36,981      18,681      18,362 
                                     ------      --------      --------      ------     ------      ------     -------- 
Other expense (income) 
 Interest expense, net               4,536        3,918         5,269        4,307       4,421       5,686       4,388 
 Foreign exchange (gain) 
   loss                               (212)        (609)         (784)        (712)        852       1,258 
                                     ------      --------      --------      ------     ------      ------     -------- 
                                     4,324        3,309         4,485        3,595       5,273       6,944       4,388 
                                     ------      --------      --------      ------     ------      ------     -------- 
Income before taxes and equity 
  investee loss (gain)              44,551       33,010(a)     43,076(a)    35,004      31,708      11,737      13,974 
Taxes on income                     19,411       14,147        18,445       14,924      13,506       6,834       6,835 
Equity investee loss (gain)            (68)         351           405          435       1,391         303         394 
                                     ------      --------      --------      ------     ------      ------     -------- 

Net income before cumulative 
  effect of change in 
  accounting method                 25,208       18,512        24,226       19,645      16,811       4,600       6,745 
Cumulative effect of change in 
  method of accounting for 
  postretirement benefits other 
  than pensions                                                                                      4,334 
                                     ------      --------      --------      ------     ------      ------     -------- 
Net income                        $ 25,208     $ 18,512(a)   $ 24,226(a)  $ 19,645    $ 16,811    $    266    $  6,745 
                                     ======      ========      ========      ======     ======      ======     ======== 
Balance Sheet Data 
  (at end of period): 
 Working capital                  $ 47,453     $ 27,362      $ 18,472     $ 12,961    $ 12,076    $ 15,451    $ 12,817 
 Total assets                      402,592      332,257       322,510      271,992     229,693     225,337     183,174 
 Long-term debt                    118,165       97,711        89,836       75,178      69,239      77,916      88,801 
 Stockholder's equity              105,872       78,361        82,517       63,908      49,388      37,197      37,206 
</TABLE>
- ------------- 
(a) Excluding the impact of the second quarter 1995 restructuring charge 
    totalling $4,616 ($2,770 net of tax), income from operations, income 
    before taxes and equity investee loss and net income for the nine months 
    ended September 30, 1995 was $40,935, $37,626 and $21,282, respectively, 
    and for the year ended December 31, 1995 was $52,177, $47,692 and 
    $26,996, respectively. 

                                     116 
<PAGE> 

                  PRO FORMA FINANCIAL INFORMATION OF COVANCE 

  The unaudited pro forma combined statements of income for the nine months 
ended September 30, 1996 and the year ended December 31, 1995 present the 
results of operations of Covance assuming that the Covance Spin-Off 
Distribution had been completed as of January 1, 1995. The unaudited pro 
forma combined balance sheet as of September 30, 1996 presents the combined 
financial position of Covance assuming that the Covance Spin-Off Distribution 
had been completed on that date. In the opinion of Covance management, the 
unaudited pro forma combined financial information of Covance ("Covance Pro 
Forma Financial Information") includes all material adjustments necessary to 
restate Covance's historical results. The adjustments required to reflect 
such assumptions are described in the Notes to the Covance Pro Forma 
Financial Information and are set forth in the "Pro Forma Adjustments" 
column. 

  The Covance Pro Forma Financial Information should be read in conjunction 
with the Covance Financial Statements and notes thereto included elsewhere 
herein. The Covance Pro Forma Financial Information presented is for 
informational purposes only and may not necessarily reflect the future 
results of operations or financial position or what the results of operations 
or financial position would have been had the Covance Spin-Off Distribution 
occurred as assumed herein, or had Covance been operated as an independent 
company during the periods shown. 

                                     117 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
               UNAUDITED PRO FORMA COMBINED STATEMENT OF INCOME 
                     Nine Months Ended September 30, 1996 

<TABLE>
<CAPTION>
                                                                  Pro Forma 
                                                   Historical    Adjustments      As Adjusted 
                                                   ----------    -----------    --------------- 
                                                  (in thousands, except share and per share data) 

<C>                                                 <C>            <C>            <C>    
Net revenues                                        $357,406       $              $   357,406 

Cost and expenses 
 Cost of revenue                                     232,828                          232,828 
 Selling, general and administrative expenses         57,573         1,500 (a)         59,073 
 Depreciation and amortization                        18,130                           18,130 
                                                      --------     ----------      ------------- 
  Total                                              308,531         1,500            310,031 
                                                      --------     ----------      ------------- 
Income from operations                                48,875        (1,500)            47,375 
                                                      --------     ----------      ------------- 
Other expense 
 Interest expense, net                                 4,536               (b)          4,536 
 Foreign exchange loss                                  (212)                            (212) 
                                                      --------     ----------      ------------- 
                                                       4,324                            4,324 
                                                      --------     ----------      ------------- 
Income before taxes and equity investee loss          44,551        (1,500)            43,051 
Taxes on income                                       19,411          (593)(c)         18,818 
Equity investee (gain)                                   (68)                             (68) 
                                                      --------     ----------      ------------- 

Net income                                          $ 25,208       $  (907)       $    24,301 
                                                      ========     ==========      ============= 

Pro forma shares outstanding                                                       56,903,469(d) 

Net income per share                                                              $      0.43(e) 

</TABLE>

The accompanying notes to unaudited pro forma combined financial information 
are an integral part hereof. 

                                     118 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
               UNAUDITED PRO FORMA COMBINED STATEMENT OF INCOME 
                         Year Ended December 31, 1995 

<TABLE>
<CAPTION>
                                                                  Pro Forma 
                                                   Historical    Adjustments      As Adjusted 
                                                   ----------    -----------    --------------- 
                                                    (in thousands, except share and per share data) 
<C>                                                 <C>            <C>            <C>            
Net revenues                                        $409,174       $              $   409,174 

Cost and expenses 
 Cost of revenue                                     270,726                          270,726 
 Selling, general and administrative expenses         64,201         2,000 (a)         66,201 
 Restructuring charge                                  4,616                            4,616 
 Depreciation and amortization                        22,070                           22,070 
                                                      --------     ----------      ------------- 
  Total                                              361,613         2,000            363,613 
                                                      --------     ----------      ------------- 
Income from operations                                47,561        (2,000)            45,561 
                                                      --------     ----------      ------------- 
Other expense (income) 
 Interest expense, net                                 5,269               (b)          5,269 
 Foreign exchange (gain)                                (784)                            (784) 
                                                      --------     ----------      ------------- 
                                                       4,485                            4,485 
Income before taxes and equity investee loss          43,076        (2,000)            41,076 
Taxes on income                                       18,445          (790)(c)         17,655 
Equity investee loss                                     405                              405 
                                                      --------     ----------      ------------- 
Net income                                          $ 24,226       $(1,210)       $    23,016 
                                                      ========     ==========      ============= 

Pro forma shares outstanding                                                       56,903,469(d) 

Net income per share                                                              $      0.40(e) 
</TABLE>

The accompanying notes to unaudited pro forma combined financial information 
are an integral part hereof. 

                                     119 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
                  UNAUDITED PRO FORMA COMBINED BALANCE SHEET 
                              September 30, 1996 

<TABLE>
<CAPTION>

                                                                Pro Forma         As 
                                                Historical     Adjustments     Adjusted 
                                                 ----------    ------------   ---------- 
                                                             (in thousands) 
<C>                                              <C>            <C>            <C>         
Assets 
Current Assets: 
 Cash and cash equivalents                       $ 13,551       $              $ 13,551 
 Accounts receivable, net                          95,690                        95,690 
 Unbilled services                                 43,110                        43,110 
 Inventory                                         14,718                        14,718 
 Deferred income taxes                             14,273                        14,273 
 Prepaid expenses and other assets                 20,639                        20,639 
                                                   --------     -----------     -------- 
  Total Current Assets                            201,981                       201,981 

Property and equipment, net                       143,956                       143,956 
Goodwill, net                                      43,443                        43,443 
Other assets                                       13,212                        13,212 
                                                   --------     -----------     -------- 
  Total Assets                                   $402,592       $              $402,592 
                                                   ========     ===========     ======== 

Liabilities and Stockholder's Equity 
Current Liabilities: 
 Trade accounts payable                          $ 23,627                      $ 23,627 
 Accrued payroll and benefits                      30,058                        30,058 
 Accrued expenses and other liabilities            36,410       $   5,000 (f)    41,410 
 Unearned revenue                                  46,025                        46,025 
 Income taxes payable                              18,408         (10,000)(g)     8,408 
                                                   --------     -----------     -------- 
  Total Current Liabilities                       154,528          (5,000)      149,528 
                                                   --------     -----------     -------- 

Long-term debt                                                    128,165 (g)   128,165 
Due to Corning Incorporated and affiliates        118,165        (118,165)(g) 
Deferred income taxes                               9,583          (9,678)(f)       (95) 
Other liabilities                                  14,444                        14,444 
                                                   --------     -----------     -------- 
  Total Liabilities                               296,720          (4,678)      292,042 
                                                   --------     -----------     -------- 

Commitments and Contingent Liabilities 
Stockholder's Equity: 
 Contributed capital                               32,368          22,500 (f)    54,868 
 Retained earnings                                 70,505         (17,822)(f)    52,683 
 Cumulative translation adjustment                  2,999                         2,999 
                                                   --------     -----------     -------- 
  Total Stockholder's Equity                      105,872           4,678       110,550 
                                                   --------     -----------     -------- 
Total Liabilities and 
 Stockholder's Equity                            $402,592       $              $402,592 
                                                   ========     ===========     ======== 

</TABLE>

The accompanying notes to unaudited pro forma combined financial information 
are an integral part hereof. 

                                     120 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         NOTES TO UNAUDITED PRO FORMA COMBINED FINANCIAL INFORMATION 

Note 1--Pro Forma Adjustments: 

Statements of Income 

(a) The pro forma adjustment to selling, general and administrative expenses 
    represents estimated incremental administrative overhead costs associated 
    with being a public company. 

(b) Immediately prior to the Covance Spin-Off Distribution, Covance will 
    incur long-term bank borrowings to repay Corning and affiliates for all 
    intercompany borrowings and income tax liabilities due at the date of the 
    Covance Spin-Off Distribution. Assuming the Covance Spin-Off Distribution 
    occurred on September 30, 1996, such borrowings would aggregate 
    approximately $128.2 million. Since the assumed interest rate on these 
    borrowings of 6.0% approximates the blended rate on Covance's historical 
    borrowings from Corning, no pro forma adjustment to interest expense is 
    necessary. If the interest rate on the bank borrowings fluctuates by 
    1/8%, interest expense fluctuates by approximately $160,000 annually. 

(c) The pro forma adjustment to taxes on income represents the estimated 
    income tax benefit of pro forma adjustment (a) above at an effective tax 
    rate of 39.5%. 

(d) The pro forma common shares outstanding represents Covance management's 
    current estimate of the number of shares to be outstanding after the 
    Covance Spin-Off Distribution. Management's estimate includes (a) the 
    issuance of approximately 56.0 million shares of Covance Common Stock at 
    an exchange ratio of one share of Covance Common Stock issued for every 
    four shares of Corning Common Stock outstanding and (b) the issuance of 
    an estimated 900,000 shares into the employee stock ownership and other 
    benefit plans. Covance management's estimate of shares outstanding is 
    subject to change as the result of normal issuances and repurchases of 
    Corning Common Stock prior to the date of the Covance Spin-Off 
    Distribution and finalization of the proposed structure of the employee 
    stock ownership plan. 

Net Income Per Share 

(e) Net income per share is computed by dividing net income by the pro forma 
    number of shares of common stock outstanding. Common stock equivalents 
    are not included in the net income per share computation because they do 
    not result in material dilution. Historical net income per share is not 
    presented as Covance's historical capital structure is not comparable to 
    periods subsequent to the Covance Spin-Off Distribution. 

Balance Sheet 

(f) The pro forma adjustments to accrued expenses and other liabilities, 
    contributed capital, deferred income taxes and retained earnings 
    represent costs directly related to the Covance Spin-Off Distribution 
    expected to be incurred during the fourth quarter of 1996. Such amounts, 
    which consist of direct costs of the Covance Spin-Off Distribution 
    (estimated at $5.0 million) and one-time charges associated with the 
    issuance of shares into the employee stock ownership (estimated at $21.0 
    million) and other benefit plans (estimated at $1.5 million), which 
    amounts represent the estimated fair market value of such shares at the 
    expected date of issuance, have not been reflected in the Unaudited Pro 
    Forma Combined Statements of Income because they are non-recurring. The 
    amount of the charges associated with the issuance of shares into the 
    employee stock ownership and other benefit plans is subject to change 
    based on the market price of the Covance Common Stock on the Distribution 
    Date. 

(g) The pro forma adjustments to long-term debt, due to Corning and 
    affiliates and income taxes payable reflect the borrowings to be incurred 
    in connection with the Covance Spin-Off Distribution. Immediately prior 
    to the Covance Spin-Off Distribution, Covance will incur long-term bank 
    borrowings to repay Corning and affiliates for all intercompany 
    borrowings and income tax liabilities. Assuming the Covance Spin-Off 
    Distribution occurred on September 30, 1996 such borrowings would 
    aggregate approximately $128.2 million. 

                                     121 
<PAGE> 

                     MANAGEMENT'S DISCUSSION AND ANALYSIS 
                    OF FINANCIAL CONDITION AND RESULTS OF 
                            OPERATIONS OF COVANCE 

Overview 

  Covance is a leading CRO providing a wide range of integrated product 
development services on a worldwide basis to the biotechnology, 
pharmaceutical and medical device industries. In addition, and to a lesser 
extent, Covance provides services such as health economics for managed care 
organizations, hospitals and health care provider networks, and early 
development and laboratory testing services to the chemical, agrochemical and 
food industries. The foregoing services can be broadly classified into six 
lines of business: preclinical, biomanufacturing, clinical and periapproval, 
central laboratory, clinical packaging, and health economics. These six lines 
of business can be further categorized as non-clinical (preclinical and 
biomanufacturing) and clinical (clinical and periapproval, central 
laboratory, clinical packaging and health economics). Covance believes it is 
one of the largest biopharmaceutical CROs, based on estimated 1995 annual net 
revenue, and one of only a few that are capable of providing comprehensive 
global product development services. Covance offers its clients high quality 
services designed to reduce product development time, allowing them to 
introduce their products into the marketplace faster and, thus, maximize the 
period of marketing exclusivity and monetary return on their investments. 
Additionally, Covance's comprehensive services and broad experience provide 
clients with a variable cost alternative to fixed cost internal development 
capabilities. 

   The businesses that today constitute Covance were acquired by Corning, 
starting in 1987, as part of a strategy to create a global, integrated and 
full service product development company. In keeping with this strategy, 
during the period 1994 through the present, Covance has purchased the 
remaining interest in a jointly owned company, acquired a significant 
minority interest in a complementary service business, acquired two new 
businesses and formed a major new business venture. Specifically, in April 
1994, Covance acquired the remaining interest in SciCor S.A., a provider of 
central laboratory testing services based in Switzerland. The transaction was 
accounted for as a purchase business combination. In October 1994, Covance 
acquired a significant minority equity position in Bio- Imaging Technologies, 
Inc. ("Bio-Imaging"), which uses proprietary imaging technology to quantify 
the diagnostic and therapeutic effectiveness of experimental drugs and 
devices. Covance expanded its offering of value added product development 
services in January 1995 with the acquisition of National Packaging Systems, 
Inc., a leading clinical packaging company. The transaction was accounted for 
as a purchase business combination. In February 1995, Covance formed Covance 
Biotechnology, a majority-owned company which will enable Covance to engage 
in biomanufacturing. In recognition of the rapid changes in the 
biopharmaceutical industry's marketplace, particularly the need for the 
industry to further demonstrate the benefits and cost effectiveness of their 
products to payors, Covance purchased in March 1996 all the assets and 
substantially all of the liabilities of Health Technology Associates, Inc. 
("HTA"), a leading health economics company, in a transaction accounted for 
as a purchase business combination. In October 1996, Covance expanded its 
clinical packaging capabilities to Europe with the purchase of Swiss based 
CRS Pacamed AG (now known as Covance Pharmaceutical Packaging Services AG). 
In addition, Covance acquired an 81,000 square foot facility in Horsham, 
England, which will be used, among other things, to provide clinical 
packaging services in Europe. 

   During the fiscal year ended December 31, 1995, approximately 
three-quarters of Covance's net revenues were earned under contracts, which 
generally range in duration from a few months to two years. Revenue from 
these contracts is recognized as costs are incurred on the basis of the 
relationship between costs incurred and estimated total costs. Typically, 
Covance's contracts in the preclinical, central laboratory, clinical 
packaging and health economics areas are fixed price or fee-for-service and 
in the clinical and periapproval areas are fee-for-service with a cap. To a 
lesser extent, some of the contracts in the clinical and periapproval areas 
are fixed price or fee-for-service without a cap. The contracts may contain 
provisions for renegotiation for cost overruns arising from changes in the 
level of work scope. Renegotiated amounts are included in net revenues when 
earned and realization is assured. In some cases, for multi-year contracts 
involving preclinical and clinical and periapproval trials, a portion of the 
contract fee is paid at the time the trial is initiated, with 
performance-based installments payable over the contract duration, in some 
cases on a milestone achievement basis. Covance routinely subcontracts with 
independent physician investigators in connection with multi-site clinical 
trials. Investigator fees are not reflected in net revenues or expenses since 
such fees are granted by customers on a "pass-thru basis" without risk or 
reward to Covance. While most contracts are terminable either immediately or 
upon notice by the client, they typically require payment 

                                     122 
<PAGE> 

of expenses to wind down a study and fees earned to date, and, in some cases, 
a termination fee or a payment of some portion of the fees or profit that 
could have been earned under the contract if it had not been terminated 
early. 

   Covance's cost of revenue includes appropriate amounts necessary to 
complete the net revenues and earnings process and includes direct labor and 
related benefit charges, other direct costs and allocable expenses (including 
indirect labor, facility charges and information technology costs). These 
costs, as a percentage of net revenues, tend to fluctuate from one period to 
another (generally within a range of up to 2% in either direction) 
principally as a result of changes in labor utilization and the mix of 
service offerings involving hundreds of studies conducted during any period 
of time. Accordingly, changes in cost of revenue as a percentage of net 
revenues plus or minus 2% are expected from one period to another. 

Results of Operations 
  Three Months Ended September 30, 1996 Compared with Three Months Ended 
September 30, 1995. Net revenues increased 19.9% to $127.2 million for the 
three months ended September 30, 1996 from $106.1 million for the 
corresponding 1995 period. Excluding the impact of the 1996 acquisition of 
HTA, growth in net revenues was 14.3%. Net revenues from Covance's combined 
clinical lines of business, excluding the recently acquired health economics 
business, grew in excess of 15% benefitting from the continuing trend in 
outsourcing of clinical development activities, while net revenues from 
Covance's preclinical business grew in excess of 10%. 

   Cost of revenue increased 18.8% to $83.2 million for the three months 
ended September 30, 1996 from $70.1 million for the corresponding 1995 period 
as a result of the increase in net revenues. Cost of revenue, as a percentage 
of net revenues, decreased to 65.4% for the three months ended September 30, 
1996 from 66.0% for the corresponding 1995 period. 

   Overall, selling, general and administrative expense, which consists 
primarily of administrative payroll and related benefit charges, advertising 
and promotional expenses, administrative travel and allocable expenses 
(facility charges and information technology costs), increased 22.2% to $20.6 
million for the three months ended September 30, 1996 from $16.9 million for 
the corresponding 1995 period. As a percentage of net revenues, selling, 
general and administrative expense increased to 16.2% for the quarter ended 
September 30, 1996 from 15.9% for the corresponding 1995 period. Contributing 
to the increase in selling, general and administrative expense were a 
continuing increase in Covance's corporate center function, administrative 
costs associated with the establishment of Covance's new Singapore operation 
and the evaluation of further geographic expansion opportunities, partially 
offset by a reduction in certain administrative costs allocated by Corning 
and affiliates. 

   Depreciation and amortization increased 6.5% to $5.8 million or 4.6% of 
net revenues for the three months ended September 30, 1996 from $5.5 million 
or 5.2% of net revenues for the corresponding 1995 period as the growth in 
net revenues outpaced the increase in these non-cash charges. 

   Income from operations increased 28.0% to $17.5 million or 13.8% of net 
revenues for the quarter ended September 30, 1996 from $13.7 million or 12.9% 
of net revenues for the corresponding 1995 period. 

   Other expense increased $1.3 million for the three months ended September 
30, 1996 to $1.6 million from $0.2 million for the corresponding 1995 period, 
due to an increase in interest expense, net of $0.7 million and to larger 
foreign exchange gains recognized during the 1995 three-month period. 

   Covance's effective tax rate for the three months ended September 30, 1996 
increased to 43.4% from 42.9% for the comparable period in 1995. Since 
Covance operates on a global basis, its effective tax rate is subject to 
variation from year to year as the geographic dispersion of its pre-tax 
earnings changes. 

   Net income increased $1.6 million to $9.1 million for the quarter ended 
September 30, 1996 from $7.5 million for the corresponding 1995 period. 

   Nine Months Ended September 30, 1996 Compared with Nine Months Ended 
September 30, 1995. Net revenues increased 18.0% to $357.4 million for the 
nine months ended September 30, 1996 from $302.9 million for the 
corresponding 1995 period. Excluding the impact of the 1996 acquisition of 
HTA, growth in net revenues was 14.4%. Net revenues from Covance's combined 
clinical lines of business, excluding the newly acquired health economics 
business, grew nearly 20%, benefitting from the continuing trend in 
outsourcing of clinical development activities, while net revenues from its 
more mature preclinical line of business grew approximately 8.0%. 

                                     123 
<PAGE> 

   Cost of revenue increased 17.1% to $232.8 million for the nine months 
ended September 30, 1996 from $198.8 million for the corresponding 1995 
period as a result of the increase in net revenues. Cost of revenue, as a 
percentage of net revenues, decreased slightly to 65.1% for the nine months 
ended September 30, 1996 from 65.6% for the corresponding 1995 period. 

   Overall, selling, general and administrative expense increased 22.6% to 
$57.6 million for the nine months ended September 30, 1996 from $47.0 million 
for the corresponding 1995 period. As a percentage of net revenues, selling, 
general and administrative expense increased to 16.1% for the nine months 
ended September 30, 1996 from 15.5% for the corresponding 1995 period. 
Contributing to the increase in selling, general and administrative expenses 
were increasing pre-operating costs relative to Covance's biomanufacturing 
business, an increase in Covance's corporate center function, administrative 
costs associated with the establishment of Covance's new Singapore operation 
and the evaluation of further geographic expansion opportunities, partially 
offset by a reduction in certain administrative costs allocated by Corning 
and affiliates. 

   Depreciation and amortization increased 12.1% to $18.1 million or 5.1% of 
net revenues for the nine months ended September 30, 1996 from $16.2 million 
or 5.3% of net revenues for the corresponding 1995 period as the growth in 
net revenues outpaced the increase in these non-cash charges. 

   Income from operations increased 34.6% to $48.9 million for the nine 
months ended September 30, 1996 from $36.3 million for the corresponding 1995 
period. During the second quarter of 1995, Covance recorded a restructuring 
provision totalling $4.6 million ($2.8 million after tax) as a result of 
management's decision to discontinue certain nonstrategic operations. 
Excluding the impact of the 1995 restructuring provision, income from 
operations increased 19.4% to 13.7% of net revenues for the nine months ended 
September 30, 1996 from 13.5% of net revenues for the corresponding 1995 
period. 

   Other expense increased $1.0 million for the nine months ended September 
30, 1996 to $4.3 million from $3.3 million for the corresponding 1995 period, 
due to an increase in interest expense, net of $0.6 million and to larger 
foreign exchange gains recognized during the first nine months of 1995. 

   Covance's effective tax rate for the nine months ended September 30, 1996 
increased to 43.6% from 42.9% for the comparable period in 1995. Since 
Covance operates on a global basis, its effective tax rate is subject to 
variation from year to year as the geographic dispersion of its pre-tax 
earnings changes. 

   Net income increased $6.7 million to $25.2 million for the nine months 
ended September 30, 1996 from $18.5 million for the corresponding 1995 
period. Excluding the impact of the 1995 restructuring provision, net income 
increased $3.9 million or 18.4% for the nine months ended September 30, 1996 
compared to the corresponding 1995 period. 

   Year Ended December 31, 1995 Compared with Year Ended December 31, 
1994. Net revenues increased 28.1% to $409.2 million for 1995 from $319.5 
million for 1994. Excluding the impact of the 1995 acquisition of National 
Packaging Systems, Inc., growth in net revenues was 23.8%. Net revenues from 
Covance's combined clinical lines of business, excluding the newly acquired 
clinical packaging business, grew in excess of 35%, generally as a result of 
the growth in outsourcing of clinical development activities in 1995 as 
compared to 1994 and more specifically because of Covance's central 
laboratory's effort to complete development work on several large protease 
inhibitor studies by the end of 1995. Net revenues from Covance's preclinical 
business grew nearly 10%, largely as a result of particularly strong growth 
in Europe, fueled by new service offerings, overall volume increases and 
favorable foreign exchange rates in 1995 compared to 1994. 

   Cost of revenue increased 26.8% to $270.7 million or 66.2% of net revenues 
for 1995 from $213.5 million or 66.8% of net revenues for 1994, as a result 
of the increase in net revenues. 

   Overall, selling, general and administrative expense increased 31.3% to 
$64.2 million for 1995 from $48.9 million for 1994. As a percentage of net 
revenues these costs increased to 15.7% for 1995 from 15.3% for 1994. Largely 
contributing to the increase in selling, general and administrative expenses 
were administrative costs associated with the establishment of Covance's new 
biomanufacturing business, an increase in Covance's corporate center 
function, strategic consulting expenses incurred to reorganize a large 
portion of Covance's clinical operations into customer teams to better manage 
large scale clinical trials and increased marketing initiatives such as the 
establishment of a Lotus Notes(R) based centralized client contact database 
for use by Covance's sales force, partially 

                                     124 
<PAGE> 

offset by a non-recurring charge incurred in 1994 in connection with a 
separation payment made to Covance's then chief executive officer upon his 
resignation. 

   During 1995, Covance recorded a restructuring provision totalling $4.6 
million ($2.8 million after tax) as a result of management's decision to 
discontinue certain nonstrategic operations. The restructuring charge 
included severance costs relating to approximately 90 employees of which 
approximately 50 had been terminated as of December 31, 1995. The remaining 
employees were terminated and all other substantive activities to complete 
the restructuring plan were completed by April 30, 1996. Severance benefits 
are being paid in the form of salary continuation. The restructuring 
activities have occurred substantially in accordance with the restructuring 
plan. 

   Depreciation and amortization increased 19.2% to $22.1 million or 5.4% of 
net revenues for 1995 from $18.5 million or 5.8% of net revenues for 1994 as 
the growth in net revenues outpaced the increase in these non- cash charges. 

   Income from operations increased $9.0 million or 23.2% to $47.6 million 
for 1995 from $38.6 million for 1994. Excluding the impact of the 1995 
restructuring provision, the increase in income from operations was $13.6 
million or 35.2% to 12.8% of net revenues for 1995 from 12.1% of net revenues 
for 1994. 

   Other expense increased $0.9 million for 1995 to $4.5 million from $3.6 
million for 1994. This increase is entirely a result of an increase in 
interest expense relating principally to 1995 acquisition activity. 
Substantially all borrowings to date have been from Corning. 

   Covance's effective tax rate for 1995 increased slightly to 42.8% from 
42.6% for 1994. 

   Net income increased 23.3% to $24.2 million for 1995 from $19.6 million 
for 1994. Excluding the impact of the 1995 restructuring provision, the 
increase in net income was $7.4 million or 37.4% for 1995. 

   Year Ended December 31, 1994 Compared with Year Ended December 31, 
1993. Net revenues increased 10.3% to $319.5 million for 1994 from $289.7 
million for 1993. Excluding the impact of 1994 acquisitions, net revenues 
growth was 7.9%. Net revenues from Covance's combined clinical lines of 
business grew nearly 20%, largely due to growth in the European clinical and 
periapproval and central laboratory operations. Net revenues from Covance's 
preclinical operations was relatively unchanged compared to 1993 due to low 
volume together with pricing pressures in various product line offerings. 

   Cost of revenue increased 10.7% to $213.5 million or 66.8% of net revenues 
for 1994 from $192.8 million or 66.5% of net revenues for 1993. 

   Overall, selling, general and administrative expense increased 13.8% to 
$48.9 million or 15.3% of net revenues for 1994 from $42.9 million or 14.8% 
of net revenues for 1993. Largely contributing to the increase in selling, 
general and administrative expenses was a separation payment made to 
Covance's then chief executive officer upon his resignation. Exclusive of 
this non-recurring charge, selling, general and administrative expenses were 
relatively unchanged from 1993. 

   Depreciation and amortization increased 9.0% to $18.5 million or 5.8% of 
net revenues for 1994 from $17.0 million or 5.9% of net revenues for 1993 as 
the growth in net revenues outpaced the increase in these non-cash charges. 

   Income from operations increased 4.4% to $38.6 million or 12.1% of net 
revenues for 1994 from $37.0 million or 12.8% of net revenues for 1993. 

   Other expense decreased $1.7 million for 1994 to $3.6 million versus $5.3 
million for 1993. This reduction is a result of a net foreign currency 
transaction gain of $0.7 million reported for 1994 versus a net foreign 
currency transaction loss of $0.9 million reported for 1993. 

   Covance's effective tax rate for 1994 remained unchanged from 1993 at 
42.6%. 

   Net income increased 16.9% or $2.8 million to $19.6 million for 1994 from 
$16.8 million for 1993. 

Quarterly Results 
  Covance's quarterly operating results are subject to variation, and are 
expected to continue to be subject to variation, as a result of factors such 
as delays in initiating or completing significant preclinical and clinical 
and 

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<PAGE> 

periapproval trials, termination of preclinical and clinical and periapproval 
trials, acquisitions and exchange rate fluctuations. Delays and terminations 
of studies or trials are often the result of actions taken by clients or 
regulatory authorities and are not typically controllable by Covance. Since a 
large amount of Covance's operating costs are relatively fixed while revenue 
is subject to fluctuation, minor variations in the commencement, progress or 
completion of preclinical and clinical and periapproval trials may cause 
significant variations in quarterly operating results. 

   The following table presents unaudited quarterly operating results of 
Covance for each of the ten most recent fiscal quarters in the period ended 
September 30, 1996. In the opinion of Covance, this information has been 
prepared on the same basis as the Audited Covance Financial Statements and 
reflects all adjustments (consisting only of normal recurring adjustments) 
necessary for a fair presentation of results of operations for those periods. 
This quarterly financial data should be read in conjunction with the Audited 
Covance Financial Statements and notes thereto included elsewhere herein. The 
operating results for any quarter are not necessarily indicative of the 
results to be expected in any future period. See "Risk Factors--Risks 
Relating to Covance--Volatility of Quarterly Operating Results." 

<TABLE>
<CAPTION>

                                                                      Quarter Ended 
                   -----------------------------------------------------------------------------------------------------------------
                     June      Sept.       Dec.       Mar.                    Sept. 
                     30,        30,         31,       31,       June 30,       30,      Dec. 31,    Mar. 31,    June 30,   Sept. 30,
                     1994       1994       1994       1995        1995        1995        1995        1996        1996       1996 
                   -------    --------   -------    -------     ---------   --------    --------   --------    --------    ---------
                                                                      (in thousands) 
<C>                <C>        <C>         <C>       <C>         <C>         <C>         <C>         <C>         <C>        <C>      
Net revenues ...   $77,762    $82,904     $84,612   $91,974     $104,813    $106,099    $106,288    $108,697    $121,530   $127,179 
Operating 
  expenses ......   66,685     73,214      74,967    78,991       95,148      92,428      95,046      94,659     104,195    109,677 
                   --------   -------     -------   -------     --------    --------    --------    --------    --------   --------
Income from 
  operations ...    11,077      9,690       9,645    12,983        9,665(a)   13,671      11,242      14,038      17,335     17,502 
Other expense, 
  net  ............     876     1,030         897     1,434        1,644         231       1,176       1,159       1,615      1,550 
                   --------   -------     -------   -------     --------    --------    --------    --------    --------   --------
Pre-tax income 
  ..................  10,201    8,660       8,748    11,549        8,021(a)   13,440      10,066      12,879      15,720     15,952 
Income taxes ...     4,335      3,693       3,732     4,953        3,423       5,771       4,298       5,619       6,861      6,931 
Equity investee 
  loss (gain) ..       140         --          87        49          149         153          54         (44)         29        (53)
                   --------   -------     -------   -------     --------    --------    --------    --------    --------   --------
Net income  .....  $ 5,726    $ 4,967     $ 4,929   $ 6,547     $  4,449(a) $  7,516    $  5,714    $  7,304    $  8,830   $  9,074 
                      =====     ======      =====      =====      =======     ======      ======      ======      ======   ======== 
</TABLE>

- ------------- 

(a) Excluding the impact of the second quarter 1995 restructuring provision 
    totalling $4,616 ($2,770 net of tax), income from operations, pre-tax 
    income and net income were $14,281, $12,637 and $7,219 respectively. 

Liquidity and Capital Resources 
  Historically, Covance has participated in the centralized treasury and cash 
management processes of Corning. For domestic operations, cash received from 
operations was generally transferred to Corning on a daily basis. For 
international operations, excess cash was transferred to Corning 
periodically. Cash disbursements for operations were funded as needed from 
Corning. From time to time excess cash balances were maintained at Covance, 
generally for specific cash requirements. 
   
   Covance is currently negotiating with several banks concerning the 
establishment of the Covance Credit Facility. Covance expects that the 
Covance Credit Facility will provide for borrowings of up to $250 million on 
an unsecured basis, carry interest at LIBOR plus approximately 37.5 basis 
points and mature in five years. Covance intends to borrow under the Covance 
Credit Facility before the Covance Spin-Off Distribution to repay Corning and 
affiliates for all of its intercompany borrowings and income tax liabilities. 
Assuming the borrowing and Covance Spin-Off Distribution both occurred on 
September 30, 1996, Covance would borrow approximately $128.2 million for 
such purpose. This would result in Covance's debt to equity and debt to 
capital ratios being 1.16:1 and 0.54:1, respectively. In addition, the 
Covance Credit Facility prohibits Covance from paying cash dividends on the 
Covance Common Stock. See "Risk Factors--Risks Relating to Covance--Absence 
of Dividends; Restrictions on Dividends Imposed by the Covance Credit 
Facility" and "Description of Certain Indebtedness of Covance." 
    
   Covance's primary cash needs on both a short and long-term basis are for 
capital expenditures, expansion of services, possible future acquisitions, 
geographic expansion, working capital and other general corporate purposes. 
In 

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<PAGE> 

October 1996, Covance acquired CRS Pacamed AG, a Swiss entity providing 
clinical packaging services for a cash payment of $14.4 million. Also in 
October 1996, Covance acquired a new facility to house its clinical 
packaging, clinical and periapproval services and health economics operations 
in Europe for a cash payment of approximately $9.0 million. Furthermore, 
Covance expects to spend approximately $9.0 million on capital expenditures 
between October 1 and December 31, 1996 for maintenance and upgrade of 
existing equipment, outfitting of new facilities and computer equipment and 
software for newly hired employees and to fund an additional payment of 
approximately $6.6 million relating to a 1995 acquisition. Assuming these 
expenditures occur prior to the Covance Spin-Off Distribution, Covance 
estimates that its debt at the Distribution Date will be approximately $135 
million to $145 million. 

   Covance's management believes that the Covance Credit Facility will 
provide it with sufficient financial flexibility and ready access to cash on 
both a short-term and a long-term basis to fund, as required, capital 
expenditures, potential future acquisitions and other longer-term growth 
opportunities. 

   During the nine months ended September 30, 1996, Covance's operations 
provided net cash of $14.9 million, a decrease of $17.5 million from the 
corresponding 1995 amount. This reduction is attributable to a larger 
increase in working capital during the first nine months of 1996 as compared 
to the first nine months of 1995. During the year ended December 31, 1995, 
Covance's operations provided net cash of $45.1 million, an increase of $2.2 
million from 1994's level. 

   Investing activities for the nine months ended September 30, 1996 and the 
years ended December 31, 1995 and 1994 included acquisitions and capital 
spending to expand existing operations and purchase equipment to enhance 
scientific technology capabilities. Funding for new business acquisitions was 
provided through borrowings from Corning. Annually, cash provided by 
operations has historically been sufficient to fund capital expenditures. 

   Working capital was $47.5 million at September 30, 1996, an increase of 
$29.0 million from the December 31, 1995 level of $18.5 million. This 
increase was attributable to an increase in aggregate accounts receivable and 
unbilled services of $41.6 million or 42.8% to $138.8 million at September 
30, 1996 from $97.2 million at December 31, 1995. Covance has initiated 
collection and contract management efforts to reduce the percentage increase 
in aggregate accounts receivable and unbilled services to a level consistent 
with the increase in net revenues. Covance's ratio of current assets to 
current liabilities was 1.31 at September 30, 1996 and 1.15 at December 31, 
1995. 

   As described in Note 8 to the Audited Covance Financial Statements, a 
Covance subsidiary, Covance Biotechnology, entered into an operating lease 
arrangement in June 1995 whereby a custom-designed, fully equipped facility 
would be constructed. The lease will commence on the date of completion of 
construction of the facility, which is currently anticipated during the 
fourth quarter of 1996 and requires minimum annual lease payments of 
approximately $5.5 million. See "Risk Factors--Risks Relating to 
Covance--Biomanufacturing-- New Business Venture" and "Business of 
Covance--Services--Biomanufacturing." 

   In the fourth quarter of 1996, Covance plans to record a one-time charge 
of approximately $27.5 million associated with the Covance Spin-Off 
Distribution. The largest component of the charge will be the cost of 
establishing an employee stock ownership plan. The remainder of the charge is 
expected to consist of the direct costs of the Covance Spin-Off Distribution 
as well as the value of restricted stock awards expected to be granted. 

   In October 1995, the Financial Accounting Standards Board issued Statement 
No. 123, "Accounting for Stock- Based Compensation" ("SFAS 123"). This 
statement defines a fair value-based method of accounting for employee stock 
options and similar equity investments and encourages adoption of that method 
of accounting for employee stock compensation plans. However, it also allows 
entities to continue to measure compensation cost for employee stock 
compensation plans using the intrinsic value-based method of accounting 
prescribed by APB Opinion No. 25, "Accounting for Stock Issued to Employees" 
("APB 25"). Entities which elect to continue accounting for stock 
compensation plans utilizing APB 25 are required to disclose pro forma net 
income and earnings per share, as if the fair value-based method of 
accounting under SFAS 123 had been applied. Covance intends to account for 
the stock compensation plans pursuant to APB 25 and, as such, will include 
the pro forma disclosures required by SFAS 123 in its financial statements 
beginning in 1996. 

Foreign Currency 

  Contracts between Covance's foreign subsidiaries and its clients are 
frequently denominated in currencies other than the applicable subsidiary's 
local currency. Accordingly, payments received for services rendered under 
such 

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<PAGE> 

contracts are denominated in a currency different than the currency used for 
the payment of the subsidiary's expenses. Therefore, the subsidiary's net 
revenues, expenses and earnings are affected by fluctuations in exchange 
rates. In addition, Covance's combined financial statements are denominated 
in U.S. dollars and, accordingly, changes in exchange rates between the 
applicable foreign currency and the U.S. dollar will affect the translation 
of such subsidiary's financial results into U.S. dollars for purposes of 
reporting Covance's combined financial results. Translation adjustments are 
reported as a separate section of stockholder's equity. To date, such 
adjustments have not been material to Covance's financial statements. 

Taxes 
  Since Covance conducts operations on a global basis, Covance's effective tax 
rate has and will continue to depend upon the geographic distribution of its 
pretax earnings among locations with varying tax rates. Covance's profits are 
further impacted by changes in the tax rates of the various jurisdictions. In 
particular, as the geographic mix of Covance's pre-tax earnings among various 
tax jurisdictions changes, Covance's effective tax rate may vary from period 
to period. See Note 5 to the Audited Covance Financial Statements. 

Inflation 

   While most of Covance's net revenues are earned under contracts, the 
long-term contracts (those in excess of one year) generally include an 
inflation or cost of living adjustment for the portion of the services to be 
performed beyond one year from the contract date. As a result Covance 
believes that the effects of inflation generally do not have a material 
adverse effect on its operations or financial condition. 

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<PAGE> 

                             BUSINESS OF COVANCE 

General 

  Covance is a leading CRO providing a wide range of integrated product 
development services on a worldwide basis to the biotechnology, 
pharmaceutical and medical device industries. In addition, and to a lesser 
extent, Covance provides services such as health economics for managed care 
organizations, hospitals and health care provider networks and early 
development and laboratory testing services to the chemical, agrochemical and 
food industries. The foregoing services can be broadly classified into six 
lines of business: preclinical, biomanufacturing, clinical and periapproval, 
central laboratory, clinical packaging and health economics. These six lines 
of business can be further categorized as non-clinical (preclinical and 
biomanufacturing) and clinical (clinical and periapproval, central 
laboratory, clinical packaging and health economics). Covance believes it is 
one of the largest biopharmaceutical CROs, based on estimated 1995 annual net 
revenue, and one of a few that are capable of providing comprehensive global 
product development services. Covance offers its clients high quality 
services designed to reduce product development time, allowing them to 
introduce their products into the marketplace faster and, thus, maximize the 
period of marketing exclusivity and monetary return on their investments. 
Additionally, Covance's comprehensive services and broad experience provide 
clients with a variable cost alternative to fixed cost internal development 
capabilities. 

History 
   
  The businesses that today constitute Covance were acquired by Corning as 
part of a strategy to create a global, integrated and full service product 
development company. In 1987 Corning acquired Hazleton Corporation (recently 
known as Corning Hazleton and now known as Covance Laboratories), owner of 
leading preclinical drug safety assessment laboratories and Phase I clinical 
research units. In 1989 Corning added Phase II and Phase III clinical trials 
expertise with the acquisition of a leading, global clinical CRO, G.H. 
Besselaar Associates (recently known as Corning Besselaar and now known as 
Covance Clinical and Periapproval Services), and expanded its clinical trials 
expertise in 1990 with the purchase of PACT Inc. (recently known as Corning 
PACT and now known as Covance Clinical and Periapproval Services), a leading 
periapproval studies company. In 1991 Corning purchased SciCor Inc. (recently 
known as Corning SciCor and now known as Covance Central Laboratories), a 
clinical laboratory dedicated to the drug development process. Corning 
expanded its pharmaceutical laboratory capabilities in 1992 with the creation 
in Switzerland of a jointly owned company, SciCor S.A., and, through Covance, 
acquired 100% of this company in 1994. Focusing on innovative ways to 
accelerate the drug development cycle, Covance acquired in late 1994 a 
significant minority equity position in Bio-Imaging, which uses proprietary 
imaging technology to quantify the diagnostic and therapeutic effectiveness 
of experimental drugs and devices. Covance expanded its offering of 
value-added development services in 1995 with the acquisition of National 
Packaging Systems, Inc. (recently known as Corning National Packaging, Inc. 
and now known as Covance Pharmaceutical Packaging Services), a leading 
clinical packaging company. In 1995 Covance also formed Covance 
Biotechnology, a majority-owned company which will enable Covance to engage 
in biomanufacturing. In recognition of the rapid changes in the 
biopharmaceutical industry's marketplace, particularly the need for the 
industry to further demonstrate the benefits and cost effectiveness of their 
products to payors, Covance purchased in early 1996 HTA (now known as Covance 
Health Economics and Outcomes Services), a leading health economics company 
serving at the date of acquisition over 100 clients. In October 1996, Covance 
expanded its clinical packaging capabilities to Europe with the purchase of 
Swiss based CRS Pacamed AG (now known as Covance Pharmaceutical Packaging 
Services). In addition, Covance acquired an 81,000 square foot facility in 
Horsham, England, which will be used, among other things, to provide clinical 
packaging services in Europe. 
    
The New Drug Development Process--Overview 

  Before a new drug may be marketed to the public, it must undergo extensive 
testing and regulatory review to determine that the drug is both safe and 
effective for its intended purpose. The developmental process and typical 
corresponding time periods are as follows: 

   Preclinical Research (6 months to 3 years). In vitro ("test tube") and in 
vivo ("animal") studies are conducted to establish the basic pharmacokinetic 
effect and safety of a drug including the toxicity of the drug over a wide 
range of doses. Initially, acute toxicology studies are conducted. In the 
United States, if results warrant continuing development of the drug, the 
manufacturer (also known as the "sponsor") will file an Investigational New 
Drug 

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<PAGE> 

Application ("IND"), whereupon the FDA may grant permission to begin human 
trials (also known as "clinical trials"). 

   Preclinical studies may continue after the start of clinical trials to 
determine the longer term effects of a product. For instance, a preclinical 
study might focus on the possible side effects, metabolism and/or 
pharmacokinetic disposition of a drug. 

    Clinical Trials (3.5 to 6 years). 

   (bullet) Phase I (6 months to 1 year). This phase involves the initial 
            basic safety and pharmacology testing in approximately 20 to 100 
            human subjects, usually healthy volunteers in a closely monitored 
            setting, including studies to determine the side effect profile 
            of the drug, how the drug works, how it is affected by other 
            drugs, where it goes in the body, how long it remains active, and 
            how it is broken down and eliminated from the body. 

   (bullet) Phase II (1 to 2 years). This phase involves basic efficacy 
            (effectiveness) and dose-range testing in approximately 100 to 
            400 carefully selected patients suffering from the disease or 
            condition under study to help determine the best effective dose, 
            confirm that the drug works as expected, and provide additional 
            safety data. The trials are typically well controlled and usually 
            involve a placebo, also known as a "sugar pill." A placebo is an 
            identical tablet or solution which lacks the active substance 
            under investigation. 

   (bullet) Phase III (2 to 3 years). This phase involves efficacy and safety 
            studies in broader populations of hundreds or thousands of 
            patients at many investigational sites (hospitals and clinics) 
            and may involve placebo- controlled trials, in which the new drug 
            is compared with a placebo; studies comparing the new drug with 
            one or more drugs with established safety and efficacy profiles 
            in the same therapeutic category; or studies where there is no 
            comparison to a placebo or another drug ("uncontrolled" trials). 
            Generally, Phase III studies are intended to provide additional 
            information on drug safety and efficacy, an evaluation of the 
            risk-benefit relationship for the drug, and information for the 
            adequate labeling of the product. 

   NDA Preparation and Submission. Upon completion of Phase III trials, the 
sponsor or CRO assembles the tabulated and statistically analyzed data from 
all phases of development into a single large document, the New Drug 
Application ("NDA"), which comprises, on average, approximately 100,000 
pages. 

   FDA Review and Approval (1 to 2 years). At this stage, the FDA will 
scrutinize data from all phases of development to confirm that the sponsor 
has complied with regulations and that the drug is safe and effective for the 
specific use (or "indication") under study. Product labeling is also approved 
at this stage, which serves as a guideline to the sponsor about how its 
product can be promoted in the marketplace. 

   Treatment Investigational New Drug (May span late Phase II, Phase III, and 
FDA review). When results from Phase II or Phase III show special promise in 
the treatment of a serious condition for which existing therapeutic options 
are limited or of minimal value, the FDA may allow the manufacturer to make 
the new drug available to a larger number of patients through the regulated 
mechanism of a treatment investigational new drug ("TIND") application. 
Although less scientifically rigorous than a controlled clinical trial, a 
TIND may enroll and collect primarily safety data from thousands of patients. 
See "--Services--Clinical and Periapproval Services--Treatment 
Investigational New Drug Applications." 

   Post-Marketing Surveillance and Phase IV Studies (Periapproval). Federal 
regulation requires the sponsor to collect and periodically report to the FDA 
additional safety and efficacy data on the drug for as long as the sponsor 
markets the drug (post-marketing surveillance). If the drug is marketed 
outside the United States, these reports must include data from all countries 
in which the drug is sold. Additional studies (Phase IV) may be undertaken 
after initial approval to find new uses for the drug or to test new dosage 
formulations. All of these studies are types of "periapproval" studies. See 
"--Services--Clinical and Periapproval Services--Other Periapproval Studies." 

   Similar extensive testing and regulatory reviews are required in Europe 
and some Asian countries to determine that a new drug is safe and effective 
for its intended purpose before it can be marketed to the public. 

CRO Industry Overview 

  The CRO industry provides independent product development services to the 
pharmaceutical, biotechnology and medical device industries, and, in general, 
CROs derive substantially all of their revenue from the research 

                                     130 
<PAGE> 

and development expenditures of these industries. Today, there are a few 
full-service companies. Full-service CROs design and manage preclinical and 
clinical and periapproval studies and trials, provide health economic 
services, and provide packaging and central laboratory services and other 
services required to develop and market new products in accordance with 
applicable government regulations in the jurisdictions where the services are 
provided, including the regulations of the FDA in the United States. 

   The CRO industry is highly fragmented, with hundreds of small, 
limited-service providers, several medium- sized CROs and a few full service 
CROs with global operations. Covance believes there are currently only 
approximately 20 CROs with revenues in excess of $30 million and only four 
with revenues in excess of $100 million. As a general matter, the clinical 
CRO industry is not capital intensive and the financial costs of entry into 
the industry are relatively low. Although there are few barriers to entry for 
small, limited-service providers, Covance believes that there are significant 
barriers to becoming a full service CRO with global operations. These 
barriers include the cost, infrastructure and experience necessary to own and 
manage multiple international offices to serve the global demands of clients; 
develop sophisticated drug development processes; develop broad therapeutic 
expertise; conduct trials that accelerate the transition from preclinical to 
clinical trials; manage complex clinical trials involving large patient 
populations in numerous countries simultaneously; provide health economic 
services; and prepare multinational regulatory submissions. Capital 
requirements, however, are relatively high for CROs that provide 
sophisticated preclinical and central laboratory and data management services 
and biomanufacturing services. 

Trends Affecting the CRO Industry
 
  In 1994 worldwide expenditures on research and development by pharmaceutical 
and biotechnology companies are estimated to have been $30 billion, of which 
Covance estimates $20 billion was spent on drug development activities of the 
type offered by the CRO industry. Covance believes that approximately $3 
billion of such spending was outsourced to CROs primarily for preclinical 
testing and clinical development. 

   Covance believes that the outsourcing of drug development activities by 
pharmaceutical and biotechnology companies has been increasing and will 
continue to increase for the following reasons: 

   Cost Containment Pressures. Market forces and governmental initiatives 
have placed significant downward pressure on pharmaceutical and biotechnology 
companies' drug prices. Pressures on profit margins have arisen from 
increased competition as a result of patent expiration, market acceptance of 
generic drugs, the need for truly innovative rather than "me too" drugs and 
governmental and private efforts to reduce health care costs, especially in 
the United States. In addition, private managed care organizations are 
beginning to limit the selection of drugs that affiliated physicians may 
prescribe, thereby further increasing competition among pharmaceutical and 
biotechnology companies. Covance believes that the pharmaceutical industry is 
responding to these pressures by downsizing its research and development 
infrastructure and converting the fixed costs of maintaining such 
infrastructure to variable costs by outsourcing drug development activities 
to CROs. The downsizing of development capabilities also creates demand for 
CROs as biopharmaceutical companies experience internal development resource 
shortages when a large number of compounds emerge from the research process 
and need to undergo development. Moreover, many of these companies are 
attempting to decrease the new drug development cycle by using CROs, which 
may have greater expertise in a therapeutic area, while offering greater 
efficiency at a lower cost. Some large pharmaceutical and biotechnology 
companies now contract with large full service CROs under a single multi-year 
master agreement which allows the company to select the CRO for a broader 
array of drug development services instead of separately contracting 
individual studies or specific phases to several different CROs. The 
establishment of a master agreement itself can expedite the development 
process by avoiding the delay inherent in negotiating and reviewing separate 
agreements for each new study. Accordingly, once selected by a pharmaceutical 
company, the CRO can commence work promptly. Covance has executed a number of 
master agreements with large pharmaceutical companies and believes that it is 
in an advantageous position to enter into such agreements with additional 
pharmaceutical companies. 

   Marketplace Globalization. Pharmaceutical and biotechnology companies are 
increasingly attempting to expand the market for new drugs by pursuing 
regulatory approvals in multiple countries simultaneously rather than 
sequentially as they have in the past. Expanding the market for a drug is 
particularly important to the industry because of limited patent lives and 
the high development costs of new drugs. To gain access to the global 
marketplace, pharmaceutical and biotechnology companies are increasingly 
outsourcing development work to 

                                     131 
<PAGE> 

CROs that are deployed in key geographical markets worldwide and that are 
capable of coordinating concurrent regulatory approvals. In addition, these 
companies are increasingly using CROs that have the systems in place to 
compile and analyze large volumes of complex data from multinational clinical 
trials and prepare regulatory submissions simultaneously on a multinational 
basis. Pharmaceutical companies also are outsourcing an increasing number of 
large scale Phase III-IV studies involving thousands of patients which are 
often simultaneously conducted in multiple jurisdictions including Europe, 
North and South America, Australia and Asia. Covance believes that CROs with 
a global presence will continue to benefit from these trends. 

   Revenue Enhancement Through Faster Drug Development. Pharmaceutical and 
biotechnology companies are increasingly attempting to reduce the time 
required to bring new drugs to market. Reducing the time it takes to market a 
new drug can reduce costs and accelerate revenue realization. Currently, 
successfully developing a new drug takes approximately 8 to 12 years, which 
generally represents a significant portion of the drug's 15 to 20 year period 
of protection under most patent laws internationally (17 years in the United 
States). Industry data suggest that it generally costs between $291 million 
and $597 million to discover and develop a drug in the United States. 
Accordingly, pharmaceutical and biotechnology companies are increasingly 
examining the drug development process itself to determine ways to reduce the 
time required to bring a new drug to market. As part of this evaluation, some 
companies are establishing time goals for how long the process should take. 
Covance believes that CROs, by providing specialized development services, 
are often able to perform the needed services with a higher level of 
expertise or specialization, and more quickly, than a pharmaceutical or 
biotechnology company could perform such services internally. In addition, 
Covance believes that CROs with advanced global drug development processes 
will be more attractive to pharmaceutical and biotechnology companies. 

   Consolidation in the Pharmaceutical Industry. The pharmaceutical industry 
is consolidating as pharmaceutical companies seek to obtain cost reduction 
synergies through business combinations. Recent consolidations include some 
of the largest multinational pharmaceutical companies in the world, such as 
American Home Products-American Cyanamid Company, Glaxo-Wellcome, 
Roche-Syntex, and Pharmacia and Upjohn. Ciba-Geigy and Sandoz have also 
announced their intention to merge and form a new company, Novartis. Once 
consolidated, many pharmaceutical companies aggressively manage costs by 
reducing jobs, decentralizing the research and development process, and 
outsourcing to CROs in an effort to reduce the fixed costs associated with 
internal drug development. Covance believes that full service global CROs 
will benefit from this trend. 

   Increasingly Stringent Regulation; Need for Capabilities. Increasingly 
stringent regulatory requirements throughout the world and their 
standardization have increased the need for broader, global regulatory 
expertise. As regulatory requirements become more stringent and the need for 
sophisticated capabilities becomes more important, including regulatory 
services and advice and global drug development processes, the pharmaceutical 
and biotechnology industries are outsourcing to global CROs to take advantage 
of their capabilities and geographic presence. 

   In addition to increasingly stringent regulatory requirements, Covance 
believes that recent efforts to develop global harmonized regulatory 
standards will increase the importance of advanced global drug development 
processes among CROs. In recent years, the FDA and the corresponding 
regulatory agencies of Canada, Japan and Europe have had substantive 
discussions for the purpose of developing harmonized standards for both the 
conduct of preclinical and clinical studies and the format and content of 
applications for new drug approval. Further, the FDA encourages the use of 
computer assisted filings in an effort to expedite the approval process. 
Covance believes that CROs which stay abreast of the changing regulatory 
requirements in multiple international jurisdictions and which are able to 
rapidly improve their drug development processes will have a competitive 
advantage. 

   Therapeutic Focus. Covance believes that the economics of the marketplace 
require research and development expenditures as biopharmaceutical companies 
become focused on innovative new products, including drugs for an aging 
population and drugs for the treatment of chronic disorders and 
life-threatening conditions such as cancer, heart disease and infectious 
diseases, including AIDS. The development of therapies for chronic disorders, 
such as Alzheimer's disease or arthritis, requires complex clinical trials to 
demonstrate the therapy's effectiveness and to determine whether the drug 
causes any long-term side effects. Covance believes that CROs with the 
requisite therapeutic experience and the ability to manage complex trials 
will present an attractive development alternative for biopharmaceutical 
companies. 

   Biotechnology Industry Growth. The U.S. biotechnology industry has grown 
rapidly over the last 10 years and is introducing new therapies which require 
regulatory approval. Many biotechnology companies do not have 

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the necessary internal resources and experience (capital, equipment or 
people) to conduct preclinical studies and clinical trials. Accordingly, many 
biotechnology companies have chosen to outsource to CROs rather than expend 
significant time and resources to develop an internal preclinical or clinical 
development or biomanufacturing capability. In addition, Covance believes 
that many biotechnology companies are turning to certain CROs for 
sophisticated regulatory expertise and will also outsource manufacturing of 
their experimental compounds during the preclinical and clinical stages. 
Moreover, the biotechnology industry is rapidly expanding into Europe, and 
Covance believes that significant growth opportunities exist for CROs with an 
international presence. Further, Covance believes that the biotechnology 
companies will enter into single multi-year master agreements with CROs, as 
pharmaceutical companies have done. Covance has been serving one of the 
largest biotechnology companies for over a year pursuant to such an agreement 
and believes that it is in an advantageous position to enter into additional 
master agreements with other biotechnology companies. 

   Consolidation in the CRO Industry. As a result of competitive pressures 
and the trend towards larger and more global studies, the CRO industry is 
consolidating. For instance, two of the largest CROs, Applied Bioscience 
International Inc. ("APBI") and Pharmaceutical Product Development Inc. 
("PPD"), recently completed their merger. Such mergers and acquisitions have 
resulted in the emergence of a few large, full service CROs that have the 
capital, technical, financial and human resources to conduct all phases of 
preclinical and clinical trials on behalf of pharmaceutical and biotechnology 
companies. As pharmaceutical and biotechnology companies increasingly 
outsource development, they may turn to large CROs that provide a broad range 
of preclinical and clinical services, while at the same time they may also 
limit the number of CROs they choose to provide such services. Covance 
believes that this trend will further concentrate market share among large 
CROs with a reputation for quality, efficiency, flexibility, responsiveness 
and overall development experience and expertise and that Covance will 
benefit from this trend. 

Business Strategy 

  Covance believes it is one of the largest CROs serving the biotechnology and 
pharmaceutical industries, based on estimated 1995 net revenues, and has a 
focused strategy to provide high quality, cost effective, integrated, 
comprehensive and innovative services to assist its pharmaceutical and 
biotechnology clients develop, produce, obtain approval for and enhance the 
commercial success of their new therapeutic products worldwide. Covance has 
and will continue to execute this strategy by: hiring and retaining the best 
people available in terms of knowledge, ability and customer-focused 
attitude; continually improving its existing services and creating new 
services that respond to the demands of the biotechnology and pharmaceutical 
industries; continually improving its drug development processes; and 
selectively expanding into new locations. Covance expects that these 
improvements or additions will occur as the result of internal expansion and 
development activity, through continued linking of Covance's various services 
and through strategic acquisitions. 

   Personnel. Covance is guided by a senior management team of experts in 
drug development who in many cases have had previous careers in the relevant 
industries served by Covance, providing them insight into what Covance's 
clients need and expect from a full service CRO. Moreover, Covance has a 
performance management system that involves an interactive annual objective 
process, career development plan and annual review process designed to focus 
on both individual strengths and opportunities for growth. In general, 
Covance seeks to retain and hire the best-qualified individuals for all 
aspects of its operations, emphasizing the need for experience and a customer 
focus. Covance provides its employees with the necessary resources for 
achieving these goals, including information technology and internal and 
external training programs to enable them to more effectively perform their 
jobs. 

   Services. Covance is a full service CRO that provides a broad array of 
product development services to the biotechnology, pharmaceutical and medical 
device industries. In addition, and to a lesser extent, Covance provides 
services such as health economics for managed care organizations, hospitals 
and health care provider networks and early development and laboratory 
testing services to the chemical, agrochemical and food industries. Covance 
believes that CROs capable of offering a full range of drug development and 
manufacturing services are better able to compete for three reasons: (1) a 
full range of services provides a client with the choice of using just one 
provider to secure all of the client's development needs; (2) an integrated 
provider of these services can provide economies of scale and accelerate the 
development of the client's product through more comprehensive planning of 
the development process; and (3) early stage development provides the CRO 
with access to the client sooner in the development cycle and may promote the 
client's use of later stage development services. 

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   As part of its strategy, Covance both continually improves its existing 
services and endeavors to create new ones. Covance has implemented a total 
quality management system throughout its operations which assists the company 
in its goal of producing error-free services on time and within the client's 
budget. This management system is overseen by a quality team comprised of 
Covance's most senior executives, including its chief executive officer. This 
team meets regularly to set quality goals, to determine whether such goals 
are being met and to discuss initiatives that should be implemented to 
improve the quality of its services. As an important supplement to Covance's 
quality management system, certain of Covance's U.S. and European 
subsidiaries have received ISO 9000 and 9001 certifications based on quality 
standards established by the International Organization for Standardization. 
The ISO 9000 standards define the international requirements for creating a 
quality assurance system that will result in providing consistent service. 

   An example of Covance's efforts to continuously improve its existing 
services is the Expanded Access Program ("EAP"), one of Covance's 
periapproval offerings. EAP is a mechanism that allows innovative new 
therapies for life threatening diseases to be given to expanded populations 
prior to FDA approval pursuant to a TIND. See "-- Services--Clinical and 
Periapproval Services--Treatment Investigational New Drug Applications." In 
addition to improving its existing services, Covance also focuses on 
providing its clients new market oriented, value-added services. Some of 
these involve integrated services that rely on multidisciplinary teams drawn 
from various Covance operating units or divisions. For instance, Covance is 
duplicating in the United States a Strategic Product Development ("SPD") 
program developed in Europe that has successfully reduced the estimated time 
from preclinical testing to the first human studies. See 
"--Services--Preclinical Services." 

   Covance's new service offerings arise as a result of both "home-grown" 
activities and through strategic acquisitions. With respect to the former, in 
addition to SPD, Covance has invested in the creation of a multi-use 
biomanufacturing facility, Covance Biotechnology. See 
"--Services--Biomanufacturing." With respect to the latter, Covance added 
domestic clinical packaging capabilities through the acquisition of National 
Packaging Systems, Inc. in January 1995, European clinical packaging 
capabilities through the acquisition of CRS Pacamed in October 1996 and 
enhanced its health economics services by acquiring HTA in March 1996. 
Covance expects to continue developing services internally and making 
strategic acquisitions that are complementary to its existing services and 
that will expand its ability to serve its clients. 

   Streamlining the Drug Development Process. Covance believes that when 
selecting CROs to conduct trials the biopharmaceutical industry will become 
more demanding with respect to factors such as containing costs, reducing 
testing time frames and being able to conduct trials on a global basis. For 
CROs to become more efficient, with the resultant savings in time for 
clients, the drug development process itself will undergo continuous change. 
In recognition of this, Covance has created a dedicated team focused 
exclusively on redesigning the drug development process with the objective of 
reducing the time required to develop a new compound. The mandate of this 
team is to examine every significant process, system and information 
technology used in product development with the objective of applying the 
considerable experience and technical resources available throughout Covance. 
Currently, Covance has over 300 information systems professionals working in 
12 regional information system centers (nine in the United States and three 
in Europe) and nine satellite centers (five in the United States and four in 
Europe). All of Covance's employees at its 33 locations (both domestic and 
international) and miniframe computers and thousands of desktop computers are 
connected by a wide area network that provides global access to the expertise 
and technologies resident in the regional information system centers. These 
systems also support Covance's ability to provide integrated services and 
connect Covance to its clients. For instance, Covance's Information Access 
System permits clients to obtain real time access to their study data, and 
its drug management system based on Integrated Voice Response technology 
allows clients to more efficiently manage the distribution of their 
experimental compounds to investigational sites. See "--Services--Clinical 
and Periapproval Services-- Clinical Development Technologies." 

   In examining ways to improve the drug developmental process, Covance's 
information technology strategy is to capitalize on its existing 
heterogeneous, flexible and proprietary computer systems, which are 
time-proven through thousands of trials, and to both customize them where 
appropriate for particular client needs and incorporate new systems and 
technologies to meet changing demands in a timely and cost effective manner. 

   Geographic Expansion. Covance believes that it will become increasingly 
important to provide its full range of drug research and development services 
in all major and developing biotechnology and pharmaceutical markets, 
especially given industry trends to conduct research on new drugs outside the 
United States first and to conduct 

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clinical trials in multiple countries simultaneously. Covance has a tradition 
of serving its clients throughout the world. Through its offices, regional 
monitoring sites, laboratories and manufacturing sites in over 33 locations 
in 15 different countries and field work in 11 other countries, Covance 
believes it is a leader among CROs in its ability to deliver services 
globally. Currently, approximately 30% of Covance's 5,000 - person work force 
is based outside of the United States. 

   Covance will continue its strategy of establishing new or enhancing 
existing operations in significant biotechnology and pharmaceutical markets. 
Covance expects this will occur as the result of internal growth and through 
strategic acquisitions. For instance, Covance opened its Singapore office in 
April 1996. Singapore will serve as Covance's center for conducting clinical 
trials in Asia, a region that Covance believes will be increasingly important 
for the research, development and therapeutic use of drugs. Given the need in 
Asia to set processes and standards for conduct of clinical trials that meet 
international standards, and the Singapore government's desire to be the 
Asian center for human drug development and research, Covance is 
collaborating with the Singapore National Science and Technology Board 
concerning the Singapore government's initiative to form the Asia Pacific 
Economic Cooperation coordinating center for Good Clinical Practice. Covance 
is also discussing with its clients opening new offices in Latin America and 
Canada to serve their growing need to conduct drug development studies in 
these areas. 

Services 
  Covance is a leading CRO providing a wide range of integrated product 
development services on a worldwide basis to the biotechnology, 
pharmaceutical and medical device industries. In addition, and to a lesser 
extent, Covance provides services such as health economics for managed care 
organizations, hospitals and health care provider networks and early 
development and laboratory testing services to the chemical, agrochemical and 
food industries. The foregoing services constitute six lines of business: 
preclinical, biomanufacturing, clinical and periapproval, central laboratory, 
clinical packaging and health economics. 

Preclinical Services 

   Covance believes that it is one of the largest independent providers of 
preclinical drug safety assessment and analytical chemistry services. With 
four major laboratories, employing over 1,900 people, located in Madison, 
Wisconsin, Vienna, Virginia, Harrogate, England, and Munster, Germany and 
with an administrative office in Tokyo, Japan, Covance conducted 
approximately 1,000 toxicology studies in 1995. The preclinical services 
offered are wide-ranging, including in vivo toxicology studies (such as 
acute, subchronic and carcinogenicity studies), genetic toxicology studies 
(such as in vitro cytotoxicity, cytogenetics and gene mutation studies and 
transgenic mouse models) and chemistry services (such as in vitro metabolism, 
pharmacokinetics and bioequivalence studies). 

   The preclinical area has also been a source of innovation by introducing 
new technologies for client access to data, electronic animal identification, 
multimedia study reports and data tables and in vivo and in vitro measures of 
induced cell proliferation. Covance's preclinical group also works closely 
with its Phase I and II groups to minimize product development time and to 
provide clients with early data on the safety and efficacy of new molecules. 
This data allows clients to make a decision about whether to continue, cease 
or modify their development program. See "--Business Strategy--Services." 

   As part of its preclinical services, Covance is duplicating in the United 
States an SPD program developed in Europe that has successfully reduced the 
time from preclinical testing to the first human studies. SPD involves an 
integrated process and team drawn from Covance's preclinical and Phase I and 
II areas. In an SPD program, the compound is researched from initial 
preclinical evaluation through its first dosing in humans, including the 
filing and attainment of the IND. Specific elements of the process include 
formulation and dose delivery testing, product metabolism, chemistry, 
pharmacology, toxicology and safety testing. Through clearly defined 
objectives, plans, timetables, and coordination with clients, Covance has 
used SPD in the United Kingdom (where INDs are not required to commence Phase 
I clinical trials) on over 10 compounds and has averaged just six months to 
nine months from the start of preclinical testing to the start of a Phase I 
clinical trial. In one example, the entire preclinical testing phase was 
completed in 41/2 months with the Phase I clinical trial concluding just five 
months thereafter. The preclinical testing phase in the United States 
typically takes six months to three years and Phase I studies typically take 
six months to one year. Because INDs are required in the United States to be 
filed before human clinical trials start, it is uncertain whether SPD trial 
completion speeds in the United States will be as swift as in the United 
Kingdom, but Covance believes that an SPD program will reduce the drug 
development time in the United States. 

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   Covance also provides animals, including purpose-bred animals, for 
biomedical research. These animals are used by biopharmaceutical companies, 
university research centers and CROs, like Covance, as part of their 
preclinical in vivo safety and efficacy testing. Often, these preclinical 
studies require animals which are free of genetic anomalies to assure that 
results from the testing are accurate. In addition, animals will often need 
to be free of all pathogens, again, to ensure the integrity of the testing 
results. Through a variety of processes, technology and specifically 
constructed facilities, Covance is able to provide both purpose-bred and 
specific pathogen free animals that will meet the clients' rigorous control 
requirements. Covance is also a provider of custom polyclonal and monoclonal 
antibody services and recently opened an 18,000-square-foot state-of-the-art 
antisera production facility that complies with both GMP and GLP. Finally, 
although Covance's animal breeding facilities maintain procedures in 
accordance with applicable government regulations and company policies for 
the quarantine and handling of imported animals, including primates, there is 
a risk that these animals may be infected with diseases that may be harmful 
and even lethal to themselves and humans. In 1996 Covance, with the approval 
of the Texas Department of Health and the Centers for Disease Control, 
destroyed a shipment of monkeys from the Philippines because some had been 
infected with a sub-strain of the Ebola-Reston virus, which is lethal to 
monkeys. 
    
   Outside the area of biopharmaceutical development, Covance also provides 
early development and laboratory testing services to the chemical, 
agrochemical and food industries. For instance, Covance offers a complete 
range of services to agrochemical manufacturers to determine the potential 
risk to humans, animals and the environment from plant protection products. 
Further, Covance offers a broad range of services to the food industries 
including nutritional analysis and nutritional content fact labels. 

Biomanufacturing 

   Covance holds a majority interest in Covance Biotechnology, a company 
formed in 1995 to manufacture peptides and recombinant proteins for 
biotechnology and pharmaceutical clients in accordance with GMP for 
preclinical and clinical trials as well as for commercial sales. Covance 
Biotechnology's services will include process development services, GMP 
manufacturing by microbial and mammalian cell expression, laboratory testing, 
quality assurance and quality control and regulatory affairs assistance. 
Covance Biotechnology expects to lease and commence operations by the end of 
1996 in a biomanufacturing facility located in Research Triangle Park, North 
Carolina. Covance Biotechnology will be able to process multiple compounds 
for multiple clients simultaneously and on a scale, Covance believes, greater 
than any other contract bioprocessor. Covance Biotechnology provides an 
alternative for clients who might otherwise need to design, finance and 
construct their own facility to manufacture a compound for preclinical or 
clinical trials or commercial sale. By hiring Covance Biotechnology, a client 
can avoid the expense, time delay and risk of making additional investments 
for a compound whose safety, efficacy and commercial opportunities are 
uncertain. This allows clients to preserve their capital and lower their 
risks. See "Risk Factors--Risk Factors Relating to Covance--Covance 
Biotechnology--New Business Venture." 

   Outsourced biomanufacturing is a relatively new industry and as such 
companies in this industry are subject to all of the risks inherent in a new 
or emerging industry, including changes in the regulatory regime, an absence 
of an established earnings history, the availability of adequately trained 
management and employees, and the potential for significant client 
concentration. In an attempt to enter this industry at an early stage of its 
development, Covance Biotechnology has hired personnel from the 
biopharmaceutical industry experienced in biomanufacturing. 

   As a start-up venture, Covance Biotechnology is subject to the risks 
inherent in the establishment of a new business enterprise, including, among 
others, unanticipated construction delays, operational and manufacturing 
problems, additional and unforeseen costs and expenses and an inability to 
attract and retain clients. There can be no assurance that, even after the 
expenditure of substantial funds and efforts, Covance Biotechnology will be 
able to market successfully its biomanufacturing services. Covance 
Biotechnology's biomanufacturing facility is still under construction and is 
expected to be "mechanically" completed during the fourth quarter of 1996. 
Mechanical completion occurs when all structural aspects of the facility are 
complete, all mechanical equipment and systems are installed and a 
certificate of occupancy has been issued by an applicable governmental 
authority. After mechanical completion, the facility must be "validated," 
which means that the various equipment, systems and procedures that are 
required to manufacture a biologic must be thoroughly tested and reviewed. 
Although Covance Biotechnology has submitted proposals to a number of 
prospective biopharmaceutical clients, it has been awarded only one contract, 
but has signed a number of letters of intent for the provision of services. 
For the period ended December 31, 1995, Covance Biotechnology reported a net 
loss of approximately $1.9 million, and for the nine months ended September 
30, 1996, Covance Biotechnology reported a net loss of approximately $2.3 
million. 

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   The biomanufacturing facility is being financed through several tax 
retention operating leases provided by the Bank and, during the construction 
phase, is being leased by the General Contractor. The leases expire 10 years 
from the date of mechanical completion of the facility. The annual minimum 
lease payments are currently estimated at $5.5 million. At the expiration of 
the lease term Covance Biotechnology is liable for the unamortized balance of 
the cost of the facility, currently estimated to be approximately $37 
million. Covance Biotechnology may also choose to purchase the facility at 
specific dates over the 10 year period. Using current estimates, the purchase 
price would be approximately $54 million at the end of the first year, 
decreasing on an amortizing basis to approximately $37 million at the end of 
the tenth year. 

   Covance owns 76% of the voting capital stock of Covance Biotechnology in 
the form of convertible preferred stock (the "Covance Biotechnology Preferred 
Stock"). The remaining 24% of Covance Biotechnology's capital stock is owned 
by certain minority stockholders (the "Minority Stockholders") in the form of 
common stock. Covance's ownership in Covance Biotechnology could be reduced 
to as much as 68% of the voting capital stock if certain options granted to 
key Covance Biotechnology executives to acquire Covance Biotechnology common 
stock owned by Covance are exercised in full. The Covance Biotechnology 
Preferred Stock held by Covance entitles Covance to a 12% annual cumulative 
dividend. No dividend has been paid on the Covance Biotechnology Preferred 
Stock. Dividends on the Covance Biotechnology Preferred Stock become payable 
only if Covance Biotechnology has profits and to the extent that the Covance 
Biotechnology board of directors declares the payment of dividends. Covance 
currently does not anticipate the receipt of any such dividend until and 
unless Covance Biotechnology becomes profitable. 

   Covance Biotechnology, Covance and the Minority Stockholders entered into 
a capital contribution and shareholder agreement (the "Agreement"), which, 
among other things, limits the persons to whom the Minority Stockholders may 
transfer their Covance Biotechnology common stock, grants Covance a right of 
first refusal with respect to the transfer of Covance Biotechnology common 
stock held by the Minority Stockholders, grants Covance the right to purchase 
up to one third of the Covance Biotechnology common stock held by the 
Minority Stockholders on each of the second, third and fourth anniversary of 
the completion of the construction of the facility or, if Covance chooses not 
to exercise this right, obligates Covance Biotechnology to use its best 
efforts to arrange for the sale of such shares on certain specified terms, 
and provides for the Minority Stockholders the right to nominate up to two 
directors of Covance Biotechnology to the extent that the Minority 
Stockholders own, in the aggregate, greater than 50% of their initial equity 
position in Covance Biotechnology. The Agreement also contains certain 
provisions which restrict the circumstances and set forth the terms and 
conditions upon which Covance may provide additional capital or funds to 
Covance Biotechnology. Covance has no affirmative obligation to provide 
further funds or financial assistance of any kind to Covance Biotechnology. 

Clinical and Periapproval Services 

   Covance offers a comprehensive range of clinical trial services, including 
Phase I through III clinical studies and periapproval studies including Phase 
IIIb and Phase IV clinical studies, TINDs, post-marketing surveillance 
studies and prescription to over-the-counter switch studies ("Rx to O-T-C 
Switch"). Covance also has extensive experience in a number of therapeutic 
areas, including diseases of the cardiovascular and central nervous systems, 
endocrinology and respiratory systems, infectious diseases (including AIDS), 
and significant experience in other areas including oncology, bone metabolism 
immunology, gastroenterology, urology, dermatology and hematology. Covance 
has extensive experience in managing both small, medium and large trials in 
the United States and in many parts of the world, including Australia, 
Canada, Western, Central and Eastern Europe, Israel, Mexico and Russia. These 
trials may be conducted separately or simultaneously as part of a 
multinational development plan. In 1995 Covance completed 135 Phase I studies 
involving over 2,900 study patients through two clinical research facilities, 
a 60-bed facility in Madison, Wisconsin and a 60-bed facility in Leeds, 
England; 113 Phase II and III studies involving over 26,900 study volunteers 
and 2,100 investigational sites; and 42 Phase IIIb - IV clinical and other 
periapproval studies involving approximately 8,400 study sites and 
approximately 53,000 study patients. Through 1995, Covance has cumulatively 
been involved in 14 TINDs involving over 2,600 investigational sites and over 
25,000 patients. In addition, Covance has cumulatively conducted over 625 
Phase IIIb - Phase IV studies through 1995 involving approximately 20,000 
investigational sites and over 215,000 patients; over 34 post-marketing 
studies through 1995 involving over 74,000 investigational sites and over 
480,000 patients; and three Rx to O-T-C Switch studies through 1995 involving 
over 3,000 investigational sites and over 10,000 patients. 

   Covance can manage every aspect of the foregoing types of trials by 
providing its clients the following services: clinical development plans and 
protocol design, consulting services (clinical and data management, 
regulatory 

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advice, information systems and drug development strategy), site, 
investigator and patient enrollment, preparation and submission of TINDs, 
INDs, European study permissions, NDAs, computer assisted NDAs ("CANDAs"), 
product license applications ("PLAs"), computer assisted PLAs ("CAPLAs") and 
European submission dossiers, computerized patient randomization and dose 
assignment and tracking, Phase I - Phase IV study design and implementation, 
monitoring and safety evaluation management and reporting, data processing 
and management, statistical analyses and report writing, medical writing, GCP 
and GMP audits and, through its relationship with Bio- Imaging, medical image 
digitization and processing. Clinical trials are managed by a dedicated 
project team, which, in each case, is led by a project director who 
supervises all aspects of the clinical trial. 

   The following is a description of the core services Covance provides, 
either on an individual or integrated basis depending on client needs, as 
part of conducting clinical trials: 

     Study Design. Covance serves its clients in the critical area of study 
   design by applying its wide development experience in the preparation of 
   study protocols and case report forms ("CRFs"). The study protocol defines 
   the medical issues to be examined in evaluating the safety and efficacy of 
   the drug under study, the number of patients required to produce 
   statistically valid results, the clinical tests to be performed in the 
   study, the time period over which the study will be conducted, the 
   frequency and dosage of drug administration and the exact inclusion and 
   exclusion criteria to be met for the patients enrolled in the study. The 
   success of the study depends not only on the ability of the protocol to 
   accurately reflect requirements of regulatory authorities, but also on the 
   ability of the protocol to fit coherently with the other aspects of the 
   development process and the ultimate marketing strategy for the drug. This 
   includes outcomes and pharmacoeconomic concerns and reimbursement 
   planning. See "--Health Economics Services." 

     Once the study protocol has been finalized, CRFs must be developed to 
   record the desired information to be obtained from the clinical studies. 
   The various other disciplines involved in the drug development process, 
   including data management, statistics and regulatory affairs, must work 
   closely with the clinical trial management project team to assure that the 
   right data are acquired in a form which is most efficient for subsequent 
   data entry, management analyses and reporting. Proper CRF design is 
   critical to allowing investigators and field monitors to conduct their 
   respective jobs quickly, accurately and effectively. 

     Investigator Recruitment. During the clinical trials, administration of 
   the drug to patients is supervised by physicians, also referred to as 
   investigators, at hospitals, clinics or other locations, also referred to 
   as investigational sites. Covance solicits the participation in the study 
   of investigators who contract directly with either Covance or its client. 
   The successful rapid identification and recruitment of investigators who 
   have the appropriate expertise and an adequate base of patients who 
   satisfy the requirements of the study protocol are critical to the timely 
   completion of the trial. Covance maintains and continually expands and 
   refines its computerized database of approximately 30,000 investigators. 
   Information regarding Covance's experience with these investigators, 
   including factors relevant to rapid study initiation, are contained in the 
   database. This information allows project managers to choose the 
   appropriate investigators for a particular study in an efficient manner. 
   In addition, Covance has worked with approximately 25,000 general 
   practitioners in connection with the conduct of Phase III and IV studies. 

     Study Monitoring. Covance provides study monitoring services which 
   include investigational site initiation, patient enrollment assistance and 
   data collection through subsequent site visits. These visits also serve to 
   assure that data are gathered according to GCP, the requirements of the 
   client, as specified in the study protocol or otherwise, and applicable 
   regulations. Project management and monitoring services are the 
   operational center of all clinical studies. In most instances a project 
   will meet, exceed or fail to meet expected timeliness for completion based 
   on meeting deadlines during the first few months of study initiation. 
   Therefore, Covance focuses at an early stage on identifying and quickly 
   completing the critical rate-limiting steps of screening and selecting 
   investigators, processing pre-study regulatory paperwork, obtaining 
   institutional review board approvals and scheduling investigational site 
   initiation visits. Drugs under study cannot be released to the 
   investigational sites, and, thus, the study cannot begin until these 
   activities have been completed. 

     Clinical Data Management and Biostatistical Analysis. Covance's data 
   management and biostatistical analysis operations are managed by 
   professionals with extensive pharmaceutical and biotechnology industry 
   experience in the design and construction of local and multinational 
   clinical trial databases. Data management and biostatistical analysis 
   services are offered as discrete products and as part of an integrated 
   drug 

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   development program. During the design of development plans and protocols, 
   Covance offers consulting services relating to, and the determination of, 
   sample size parameters for patient enrollment, development of data 
   analysis plans and randomization schemes. During the conduct of clinical 
   trials, Covance assists in the rapid acquisition of clean and accurate 
   data. Following completion of the clinical trials, Covance assists in 
   report preparation and regulatory submissions. Covance's biostatisticians 
   may participate with clients in meetings with the FDA to present and 
   discuss biostatistical analyses prepared by Covance. Covance has expertise 
   in electronically capturing and integrating geographically diverse data. 
   Covance employs a variety of software, which may be specified by clients 
   or combined with customized programs developed by Covance. 

     Drug development time is reduced by performing data management and 
   biostatistical analysis activities in parallel with other drug development 
   activities where possible. For example, data management personnel work as 
   part of an integrated team with clinical program managers and field 
   monitors to continuously enter data, program output tables and listings 
   and validate the database so that there is a rapid progression from "data 
   lock," to "database freeze," to final tables and listings preparation and 
   to biostatistical analyses. Similarly, there is a close working 
   relationship with medical writing and regulatory services personnel. 

     Clinical Development Technologies. To expedite the drug development 
   process and to help reduce costs, Covance has created a proprietary drug 
   management system based on an Interactive Voice Response System ("IVRS") 
   and an Information Access System ("IAS"), which are interactive 
   information technologies. IVRS uses touch-tone telephone technology to 
   assist biopharmaceutical clients in managing the "just-in-time" delivery 
   of clinical drug supplies and patient randomization. IVRS is available in 
   multiple languages using toll free numbers and has, in some cases, 
   demonstrated up to 30% reduction in study drug waste. IAS, based on Lotus 
   Notes shareware, provides clients with 24-hour access to study data, such 
   as study patient enrollment progress, patient visit information, CRF 
   status and serious adverse event experience. In another example, by 
   incorporating new optical scanning technology and redesigning the 
   development process for a 40,000-patient Phase IV clinical trial involving 
   900 investigators, Covance was able to decrease the per patient study cost 
   by approximately 60%. 

     Medical Writing and Regulatory Services. Covance provides medical report 
   writing and regulatory services to its clients in a manner designed to 
   complement parallel development processes to reduce overall development 
   time. Strategic plan and protocol design services provided at the 
   beginning of a project, combined with clear, concise data presentation, 
   analysis and discussion at the completion of the project assist the client 
   in obtaining regulatory approvals. These services are fully integrated 
   with Covance's other services to assure maximum speed consistent with good 
   service and regulatory compliance. Services in this area include 
   integrated clinical/statistical reports, manuscripts, risk/benefit 
   assessment reports, package inserts, quality assurance and environmental 
   risk assessments. Through 1995, Covance has prepared a total of 79 INDs or 
   their equivalent. In addition, through 1995, Covance has cumulatively 
   prepared 66 NDAs, or their equivalents, in the United States or abroad, of 
   which 47 NDAs, or their equivalents, in the United States or abroad are 
   pending and 19 NDAs, or their equivalents, have been approved in the 
   United States and abroad. Further, Covance believes it was one of the 
   first CROs to develop CANDAs and CAPLAs, and Covance worked on two such 
   applications in 1995 and has completed nine such applications since their 
   inception in 1987. 

     Although Covance's clinical regulatory affairs group typically conducts 
   GCP and GMP audits as part of its overall involvement in a clinical trial, 
   because of the experience and reputation of this group, it is common for 
   the group to be hired independently by a sponsor to conduct such audits. 
   Governmental agencies have also recognized the ability of Covance's 
   regulatory affairs group. Hired by an intermediary, Covance worked in 1992 
   with the European Commission (Directorate General III) on a study 
   concerning the establishment and operations of the then proposed European 
   Medicines Evaluation Agency ("EMEA"), Europe's rough analogy to the FDA. 
   The EMEA became operational on January 1, 1995, and Covance's head of 
   European clinical regulatory affairs was listed as a co-author of the 
   report. In another example, Covance was hired in 1995 by an intermediary 
   to advise the National Drugs Advisory Board in Ireland concerning the 
   recommended structure, systems and procedures for the then proposed 
   creation of the Irish Medicines Board, which was ultimately established in 
   January 1996. 

     Treatment Investigational New Drug Applications. The TIND is an 
   application by a pharmaceutical or biotechnology sponsor and the 
   associated procedure to allow broader populations of patients to receive 
   treatment with an investigational new drug for a serious or immediate 
   life-threatening disease, such as AIDS 

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   or cancer, for which no comparable or satisfactory therapy is available. 
   This treatment is provided during the clinical trial phase of development 
   but does not typically use controlled clinical trials. Covance has had 
   substantial experience with TINDs and has developed specialized systems 
   for prompt initiation and effective operation of TIND programs, such as 
   computerized patient screening, optical scanning of CRFs and drug 
   management systems. Other special TIND programs or systems involve 
   providing project specific information to physicians, patients and patient 
   advocacy groups, and data processing, management, analyses and reporting 
   systems. 

     Covance's EAP, which is conducted pursuant to a TIND, is a mechanism 
   that allows innovative new therapies for life-threatening diseases to be 
   given to expanded populations prior to FDA approval. In one recent 
   situation, a pharmaceutical company contacted Covance to conduct an EAP 
   for a promising new treatment for AIDS. The sponsor, who had little 
   experience with EAPs and had limited supply of the new drug, required that 
   the study be conducted on a global scale (21 countries simultaneously), 
   that enrollment of patients start rapidly (within 90 days of Covance's 
   selection as the CRO) and that all components of the study, including 
   project management, data management, regulatory support and drug supply 
   management, be integrated seamlessly worldwide. To accomplish the 
   sponsor's aggressive goals, Covance formed a multidisciplinary team drawn 
   from six different locations in the United States and Europe involving the 
   clinical and periapproval and the clinical packaging operations. After 
   redesigning the EAP processes, customizing existing technology and 
   employing new systems, Covance has been able to meet or exceed the 
   client's requirements without jeopardizing quality or increasing costs. 

     Other Periapproval Studies. Besides TINDs, Phase IIIb studies (involving 
   studies conducted after NDA submission but before regulatory approval is 
   issued) and Phase IV studies, Covance performs other types of periapproval 
   studies such as post-marketing surveillance studies and Rx to O-T-C Switch 
   studies. Post- marketing surveillance studies are epidemiologically based 
   evaluations of the use of products in actual medical practice using a 
   broad range of patients. Accordingly, these studies use practicing 
   physicians to evaluate primarily the safety profile of the product under 
   actual medical practice conditions. Post-marketing surveillance studies 
   are large, typically involving over 1,000 physicians and thousands of 
   patients, and usually focus on evaluating just a limited number of key 
   clinical outcomes, such as a particular side effect. In Rx to O-T-C Switch 
   studies, Covance gathers, on behalf of a sponsor, the necessary safety 
   data to obtain regulatory permission for the sale of its drug without the 
   need of a prescription. These studies are also large, well- controlled 
   programs. 

   Central Laboratory Services 

   Covance believes that the ability to conduct high quality and 
   sophisticated central laboratory services is an integral aspect of what 
   constitutes a full service CRO. Covance's two facilities (one located in 
   the United States and the other in Switzerland) provide central laboratory 
   services dedicated exclusively to biopharmaceutical studies. These 
   facilities, which have conducted over 60 million assays from the 
   specifications of more than 3,000 protocols and have collected data from 
   over 16,500 investigational sites, provide clients with combinable data in 
   studies that can be conducted separately or multinationally and 
   simultaneously. Providing combinable data eliminates the need for 
   statistical correlation among different laboratories by using consistent 
   laboratory methods, the use of same reagent manufacturers, and the use of 
   identical clinical trial reference ranges and equipment calibration. 
   Covance also employs a proprietary clinical trials management system, 
   which Covance believes is unique, that enables it to enter a sponsor's 
   protocol requirements directly into its own database. This system, based 
   on protocol requirements, constructs the drug kits that will go to the 
   investigational sites and the requisition forms therefor, allows for 
   proper laboratory specimen collection from the investigational site, 
   sequencing of study participants visits and investigator test ordering of 
   additional tests and ensures that all demographic data is complete and 
   accurate and will produce for the client reports that are customized to 
   their specifications. 

   The laboratories provide a comprehensive audit trail by ensuring that all 
   laboratory data are traceable to source documents, are capable of 
   delivering customized data electronically within 24 hours and provide 
   safety test results within 48 hours from most locations. As the need for 
   central laboratory services expands geographically, Covance has expanded 
   the reach of its central laboratories business through a contractual 
   arrangement with a leading South African laboratory that allows Covance to 
   combine the testing capability of this laboratory with its own proprietary 
   systems. Covance expects to continue to investigate other opportunities 
   for geographical expansion of its central laboratory service offerings. 

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   Clinical Packaging 

     Covance offers full service contract packaging for the pharmaceutical 
   industry in the United States and Europe including package development and 
   design, coldformed and thermoformed blister units, blister packaging, 
   multi-dose bottle filling, clinical labeling, storage and site 
   distribution of clinical supplies and return services for unused supplies. 
   With the addition of Covance Pharmaceutical Packaging Services AG, Covance 
   packaging services and products have been expanded to include software 
   inventory and validation controls and processes and the manufacturing of 
   robotic packaging machines. Covance believes that by integrating packaging 
   services with its other clinical and periapproval services it can 
   accelerate the drug development process through operational efficiencies 
   that arise from coordinating at the outset the design of a clinical trial. 

   Health Economics 

     Covance offers a wide range of health economic services for managed care 
   organizations, hospitals, health care provider networks and pharmaceutical 
   and device manufacturers. These services include outcomes and 
   pharmacoeconomic studies, reimbursement planning services and disease 
   management services. 

   Outcomes and Pharmacoeconomic Studies. In this area, Covance offers its 
   clients a full range of strategic and analytic services, including 
   strategic planning, quality-of-life assessment, and economic studies, 
   including feasibility studies, protocol and instrument design and data 
   analysis. Outcomes studies may be prospective, often conducted in 
   conjunction with clinical trials, or retrospective. Many 
   cost-effectiveness studies employ economic modeling techniques to evaluate 
   the full financial impact of new medical technologies. For example, among 
   the studies undertaken by Covance in 1995, Covance completed a cost- 
   effectiveness study for a medical device manufacturer to determine the 
   device's clinical effectiveness in treating brain metastases and to 
   compare the cost of such treatment with other therapies. Covance also 
   completed in 1995 several quality-of-life studies that determined various 
   products' impacts on patients' lives. For example, in a study on the 
   effects of a new treatment for amyotrophic lateral sclerosis (Lou Gehrig's 
   disease), Covance designed the measures for evaluating how treatment 
   affected a patient's ability to function on a daily basis. Through 1995, 
   Covance has designed over 100 outcomes and pharmacoeconomic studies. 

   When planning studies, Covance examines the audience for the study's 
   findings to determine which of the client's concerns (e.g., regulatory 
   approval, clinical acceptance, insurer coverage or insurer payment) might 
   be more fully informed by the availability of outcomes data, and then 
   determines how such data can be efficiently collected and communicated. 
   Covance typically involves academic and clinical experts to ensure that 
   appropriate techniques are used and to enhance study credibility and 
   acceptance. Covance designs most studies with a goal of publishing its 
   findings in respected, peer-reviewed journals. 

     Covance believes that given the changing competitive pressures affecting 
   the pharmaceutical industry and the rising need to more rigorously 
   demonstrate the value of particular drugs, both in their own right and 
   compared to other drugs and treatment regimes, the ability to perform 
   outcomes and pharmacoeconomic studies will become increasingly important. 

     Reimbursement Planning. Covance offers its customers strategic 
   reimbursement and market planning services. These services enable clients 
   to enhance the commercial success of their medical products. Covance 
   analyzes, on behalf of the customer, who will pay for a medical product 
   (e.g., third-party payors such as private insurance companies or federal 
   programs like Medicare) and what economic barriers or opportunities exist 
   for the product (e.g., claims coding, coverage policy, or payment 
   amounts). This work typically involves evaluating government policies and, 
   sometimes, leads to changes in those policies. In addition, Covance often 
   offers its reimbursement planning activities in conjunction with its other 
   services that evaluate existing and potential market size, pricing, 
   distribution, and economic impact. 

     Through its Medical Technology Hotlines(R) division, Covance also 
   provides full service reimbursement case management, including: (1) 
   contacting insurers to investigate specific coverage and benefit matters, 
   resolving denied claims and educating insurers; (2) assisting 
   manufacturers in designing and effectively running their indigent patient 
   programs, pursuant to which costly new products are made available to 
   patients who cannot afford them because of inadequate insurance coverage 
   or other cost reasons; (3) designing and administering transition programs 
   for manufacturers, which includes obtaining third-party payment for a 
   product for patients who had previously received it free as part of a 
   clinical trial; and (4) conducting reimbursement training seminars for 
   clients and their customers. 

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     All of these services are supported by a dedicated information services 
   group that provides a range of data products, services and information 
   systems, including customized hospital cost reports, patient average 
   lengths of stay or mortality rates at the federal, state, local or 
   individual hospital level. The extensive economic and epidemiologic 
   databases Covance maintains are used to perform market research, determine 
   the economics of a disease or inform government authorities about the need 
   for potential policy changes. 

     Disease Management Services. Working for a variety of customers, 
   including pharmaceutical and device manufacturers, managed care 
   organizations, hospitals, provider networks and computerized medical 
   record companies, Covance designs and implements systems that track 
   patterns of care, patient outcomes, and costs, and develops programs and 
   tools designed to improve quality and decrease costs of care. Such 
   programs and tools include medical practice guidelines and computerized 
   decision support tools. For example, Covance is developing nationwide 
   standards for the optimal treatment of dialysis patients. This work is 
   being performed in conjunction with a major national professional society 
   and is being funded by a manufacturer. In another initiative, Covance has 
   started a national database to track practice patterns and outcomes 
   concerning eye care provided by ophthalmologists. Covance is analyzing the 
   national data and providing reports to individual ophthalmologists 
   regarding their performance. 

Clients and Marketing 

  Covance provides its product development services on a global basis to, 
among others, the pharmaceutical and biotechnology industries. Specifically, 
Covance serves over 270 biopharmaceutical companies, including all 50 of the 
world's largest pharmaceutical companies and 17 of the world's 25 largest 
biotechnology companies. Of the 270 biopharmaceutical companies Covance 
serves, 45 are Japanese. The Japanese biopharmaceutical companies are served 
by Covance's U. S. and European operations. For the years ended December 31, 
1995, 1994 and 1993, approximately 70%, 76% and 78%, respectively, of 
Covance's net revenues were attributed principally to U.S. operations, while 
approximately 30%, 24% and 22%, respectively, was attributed to European 
operations. Approximately 59%, 52% and 48% of Covance's net revenue during 
1995, 1994 and 1993, respectively, was attributed to Covance's clinical lines 
of business. Approximately 41%, 48% and 52% of Covance's net revenues during 
1995, 1994 and 1993, respectively, were attributed to Covance's nonclinical 
lines of business. No client accounted for 10% or more of Covance's net 
revenues in 1995, 1994, or 1993. None of Covance's clients accounted for 
greater than 5% of Covance's net revenue in the year ended December 31, 1993. 
In the years ended December 31, 1994 and 1995, one client accounted for 
greater than 5% of Covance's net revenues. In fiscal 1993, 1994 and 1995 and 
the nine months ended September 30, 1996, Covance's top five clients 
accounted for approximately 17%, 20%, 21% and 21%, respectively, of Covance's 
net revenues. See "Risk Factors--Risks Relating to Covance-- Dependence on 
Certain Industries and Clients." 

   Covance's sales activities are conducted by more than 90 business 
development people based in Covance's operations in the United States, 
Europe, Australia, Japan and Singapore. Most of Covance business development 
personnel have technical or scientific backgrounds. 

   To strengthen its sales and marketing activities, Covance introduced in 
1995 a Lotus Notes based large account management process ("LAMP") that 
allows Covance business development personnel in all locations to promptly 
ascertain the status of any new client activity with any Covance operation 
and is an important tool in managing Covance's key account program. Through 
LAMP, the key account program and dedicated resources, Covance believes it 
can better coordinate and unite the efforts of its sales and marketing 
personnel and strengthen relationships with pivotal biopharmaceutical 
clients. Covance believes that this will allow it to improve its 
understanding of its clients' organizational structure, management practices 
and product pipeline, and, thus, better serve its clients' needs. Conversely, 
LAMP also enables clients, across different business functions, to better 
understand the full range of Covance's services. 

Contractual Arrangements 

  Most of Covance's contracts in the preclinical, central laboratory, clinical 
packaging and health economics areas are fixed price or fee-for-service and 
in the clinical and periapproval areas are fee-for-service with a cap. To a 
lesser extent, some of the contracts in the clinical and periapproval areas 
are fixed price or fee-for-service without a cap. In cases where the 
contracts are fixed price, Covance bears the cost of overruns, with certain 
exceptions, but benefits if the costs are lower than anticipated. In cases 
where the contracts are fee-for-service with a cap, the 

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contracts contain an overall budget for the trial based on time and cost 
estimates. If costs are lower than anticipated, the client keeps the savings, 
but if costs are higher than estimated, then Covance is responsible for the 
overrun unless the increased cost is a result of a change requested by the 
client, such as an increase in the number of patients to be enrolled or the 
type or amount of data to be collected. Contracts may range from a few months 
to several years depending on the nature of the work performed. In some 
cases, for multiyear contracts involving either preclinical or clinical and 
periapproval trials, a portion of the contract fee is paid at the time the 
study or trial is started with the balance of the contract fee payable in 
installments over the study or trial duration and may be performance based. 
For instance, in clinical and periapproval trials, installment payments may 
be related to investigator recruitment, patient enrollment or delivery of the 
database. 

   Most of Covance's contracts for the provision of its services are 
terminable by the client either immediately or upon notice. Contracts may be 
terminated for a variety of reasons, including the failure of a product to 
satisfy safety requirements, unexpected or undesired results of the product, 
the client's decision to forego or terminate a particular study, insufficient 
enrollment or investigator recruitment, or Covance's failure to properly 
discharge its obligations thereunder. Although the contracts often require 
payment of expenses to wind down the study and fees earned to date, and in 
some cases, a termination fee or a payment of a portion of the fees or 
profits that would have been earned under the contract if the contract had 
not been terminated early, the loss of a large contract or the loss of 
multiple contracts could materially and adversely affect Covance. See "Risk 
Factors--Risks Relating to Covance--Fixed Price Nature of Contracts; Loss or 
Delay of Large Contracts." 

Backlog 

  Certain of Covance's studies and projects are performed over an extended 
period of time which may be as long as several years. With respect to such 
studies or projects, Covance maintains an order backlog to track anticipated 
net revenues for such work that has yet to be earned. Covance does not 
maintain an order backlog for all the services it provides because such 
services are performed within a short period of time or for other reasons 
where it is not practical or feasible to maintain an order backlog. 
Additionally, services appropriate for backlog measurement do not correspond 
exactly with any particular line of business. 

   Backlog is principally calculated with respect to work to be performed 
pursuant to letters of intent and contracts. Once work under a letter of 
intent or contract commences, net revenue is recognized over the life of the 
contract. In certain cases, however, Covance will work on a project prior to 
executing a letter of intent and the backlog may include the net revenue 
expected from such project. 

   No assurance can be given that Covance will be able to realize all or any 
net revenue included in backlog. Although backlog can be meaningful to 
management with respect to a particular study where study-specific 
information is known (e.g., study duration, performance clauses and other 
study-specific contract terms), Covance believes that its aggregate backlog 
as of any date is not necessarily a meaningful indicator of future results 
for a variety of reasons, including the following: First, studies vary in 
duration. For instance, some studies that are included in 1995 backlog may be 
completed in 1996, while others may be completed in later years. Second, the 
scope of studies may change, which may either increase or decrease their 
value. Third, studies included in backlog may be subject to bonus or penalty 
payments. Fourth, trials under letters of intent or contracts included in 
backlog are subject to termination or delay at any time by the client or 
regulatory authorities. Termination or delays can result from a number of 
reasons. See "--Contractual Arrangements." Delayed contracts remain in 
Covance's backlog pending determination of whether to continue, modify or 
cancel the study. 

   Using this method of measuring backlog, at December 31, 1995, 1994 and 
1993, Covance's aggregate backlog was approximately $392 million, $344 
million and $294 million, respectively. 

Competition 

  The CRO industry is highly fragmented, with participants ranging from 
hundreds of small, limited-service providers to a few full service CROs with 
global capabilities. Covance primarily competes against in-house departments 
of pharmaceutical companies, full-service CROs and, to a lesser extent, 
universities and teaching hospitals. Covance believes, based on 1995 
revenues, that the five largest CROs after itself include PPD (after its 
merger with APBI), Quintiles Transnational Corporation, Huntington 
International Holdings PLC, Parexel International Corporation and ClinTrials 
Inc. CROs compete on the basis of several factors, including reputation 

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for on-time quality performance, expertise and experience in specific 
therapeutic areas, scope of service offerings, how well such services are 
integrated, strengths in various geographic markets, price, technological 
expertise and efficient drug development processes, the ability to acquire, 
process, analyze and report data in a time-saving and accurate manner, the 
ability to manage large-scale clinical trials both domestically and 
internationally, expertise and experience in health economics and size. While 
Covance has competed effectively in these areas, there can be no assurance 
that Covance will be able to continue to do so. As a result of competitive 
pressures, the CRO industry is consolidating. This trend is likely to produce 
competition among the larger CROs for both clients and acquisition candidates 
and companies may choose to limit the CROs they are willing to work with. In 
addition, there are few barriers to entry for small, limited-service entities 
considering entering the CRO industry. These entities may compete against 
larger CROs for clients. Furthermore, the CRO industry has attracted the 
attention of the investment community, which could lead to increased 
competition by increasing the availability of financial resources for CROs. 
Increased competition may lead to price and other forms of competition that 
could have a material adverse effect on the results of operations of Covance. 
See "--CRO Industry Overview." 

Government Regulation 

  The laboratory and manufacturing services performed by Covance are subject 
to various regulatory requirements designed to ensure the quality and 
integrity of the testing and manufacturing processes. See "--The Drug 
Development Process--Overview." The industry standards for conducting 
preclinical laboratory testing are embodied in the GLP and GMP regulations 
and for central laboratory operations in Clinical Laboratory Improvement 
Amendments of 1988 ("CLIA"). Covance's central laboratories also, in limited 
circumstances and when required by a client, follow GLP. Covance's central 
laboratory in Geneva has also been certified by CAP. GMP sets forth the 
requirements for manufacturing facilities. GLP and GMP have been adopted by 
the FDA, by the Department of Health in the United Kingdom and by similar 
regulatory authorities in other parts of the world. GLP and GMP stipulate 
requirements for facilities, equipment and professional staff. The 
regulations require standardized procedures for studies, for recording and 
reporting data and for retaining appropriate records. To help ensure 
compliance, Covance has established quality assurance controls at its 
laboratory and manufacturing facilities which monitor ongoing compliance with 
GLP, GMP and CLIA regulations, as applicable, by auditing test data and 
conducting regular inspections of testing and manufacturing procedures. 

   The industry standard for the conduct of clinical research and development 
studies is embodied in the regulations for GCP. Although GCP has not been 
formally adopted by the FDA nor, with certain exceptions, by similar 
regulatory authorities in other countries, certain provisions of GCP have 
been included in FDA regulations. As a matter of practice, the FDA and many 
other regulatory authorities require that test results submitted to such 
authorities be based on studies conducted in accordance with GCP. These 
regulations require (1) complying with specific requirements governing the 
selection of qualified investigators; (2) obtaining specific written 
commitments from the investigators; (3) verifying that patient informed 
consent is obtained; (4) monitoring the validity and accuracy of data; (5) 
verifying drug or device accountability; (6) instructing investigators to 
maintain records and reports; and (7) permitting appropriate governmental 
authorities access to data for their review. Covance must also maintain 
reports for each study for specified periods for inspection by the study 
sponsor and the FDA during audits. As with GLP and GMP, noncompliance with 
GCP can result in the disqualification of data collection during the clinical 
trial. 

   Covance's standard operating procedures are written in accordance with 
regulations and guidelines appropriate to the region and the nation where 
they will be used. Within Europe, all work is carried out in accordance with 
the European Community Note for Guidance "Good Clinical Practice for Trials 
on Medicinal Products in the European Community" and the requirements of the 
applicable country. In addition, FDA regulations and guidelines serve as a 
basis for Covance's North American and Asian/Pacific standard operating 
procedures. From an international perspective, when applicable, Covance has 
implemented common standard operating procedures across regions to assure 
consistency whenever it is feasible and appropriate to do so. 

   Covance's animal import and breeding facilities are also subject to a 
variety of federal and state laws and regulations, including The Animal 
Welfare Act and the rules and regulations promulgated thereunder by the 
United States Department of Agriculture ("USDA"). These regulations establish 
the standards for the humane treatment, care and handling of animals by 
dealers and research facilities. Covance's breeding and import animal 
facilities maintain detailed standard operating procedures and the 
documentation necessary to assure compliance with 

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applicable regulations for the humane treatment of the animals in its 
custody. Besides being licensed by the USDA as both a dealer and research 
facility, this business is also accredited by the American Association for 
the Accreditation of Laboratory Animal Care and has registered assurance with 
the U.S. National Institutes of Health Office of Protection for Research 
Risks. 

   The use of controlled substances in testing for drugs of abuse is 
regulated by the Drug Enforcement Administration (the "DEA"). All Covance 
laboratories using controlled substances for testing purposes are licensed by 
the DEA. 

   Covance's U.S. laboratories are subject to licensing and regulation under 
federal, state and local laws relating to hazard communication and employee 
right-to-know regulations, the handling and disposal of medical specimens and 
hazardous waste and radioactive materials, as well as to the safety and 
health of laboratory employees. All Covance laboratories are operated in 
material compliance with applicable federal and state laws and regulations 
relating to the storage and disposal of all laboratory specimens including 
the regulations of the Environmental Protection Agency, the Nuclear 
Regulatory Commission, the Department of Transportation, the National Fire 
Protection Agency and the Resource Conservation and Recovery Act. Although 
Covance believes that it is currently in compliance in all material respects 
with such federal, state and local laws, failure to comply could subject 
Covance to denial of the right to conduct business, fines, criminal penalties 
and other enforcement actions. 

   In addition to its comprehensive regulation of safety in the workplace, 
the Occupational Safety and Health Administration has established extensive 
requirements relating to workplace safety for health care employers, whose 
workers may be exposed to blood-borne pathogens such as HIV and the hepatitis 
B virus. These regulations, among other things, require work practice 
controls, protective clothing and equipment, training, medical follow-up, 
vaccinations and other measures designed to minimize exposure to chemicals, 
and transmission of blood-borne and airborne pathogens. Furthermore, relevant 
Covance employees receive initial and periodic training to ensure compliance 
with applicable hazardous materials regulations and health and safety 
guidelines. 

   The regulations of the Department of Transportation, the Public Heath 
Service and the Postal Service apply to the surface and air transportation of 
laboratory specimens. Covance's laboratories also comply with the 
International Air Transport Association regulations, which govern 
international shipments of laboratory specimens. Furthermore, when the 
materials are sent to a foreign country, the transportation of such materials 
becomes subject to the laws, rules and regulations of such foreign country. 

Intellectual Property 

  Covance has developed certain computer software and technically derived 
procedures that provide separate services and are intended to maximize the 
quality and effectiveness of its services. Although Covance's intellectual 
property rights are important to its results of operations, Covance believes 
that such factors as the technical expertise, knowledge, ability and 
experience of Covance's professionals are more important, and that, overall, 
these technological capabilities provide significant benefits to its clients. 

Employees 

  At September 1996 Covance had approximately 5,000 employees, approximately 
30% of whom are employed outside of the United States. Approximately 32 of 
Covance's employees hold M.D. degrees, 134 hold Ph.D. degrees, 8 hold 
Pharm.D. degrees, 25 hold DVM degrees and approximately 128 hold masters or 
other postgraduate degrees. Covance believes that its relations with its 
employees are good. 

   Covance's performance depends on its ability to attract and retain 
qualified professional, scientific and technical staff. The level of 
competition among employers for such skilled personnel is high. Covance 
believes that its employee compensation and benefit plans, including its 
recently adopted employee stock ownership plan, enhance employee morale, 
professional commitment and work productivity and provide an incentive for 
employees to remain with Covance. While Covance has not experienced any 
significant problems in attracting or retaining qualified staff, there can be 
no assurance that Covance will be able to avoid such problems in the future. 

Facilities 

  Covance both owns and leases its facilities. Covance's principal executive 
offices are located in Princeton, New Jersey where it leases approximately 
157,000 square feet of space. The lease expires in 2004. Because its 

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existing space is approximately 95% occupied and to accommodate its growth, 
Covance is currently in discussions with the landlord of this facility to 
either lease or purchase additional space in Princeton, New Jersey. No 
assurance can be provided that these discussions will be satisfactorily 
resolved. Covance owns its 397,000 square-foot preclinical laboratory located 
in Madison, Wisconsin and its 205,000 square-foot preclinical laboratory in 
Harrogate, England. Covance leases most of its 201,000 square-foot 
preclinical laboratory in Vienna, Virginia. It also owns several of the 
buildings. The leases expire in 1999 and have a 10-year renewal option. 
Covance also leases its 152,000 square-foot pharmaceutical laboratory in 
Indianapolis, Indiana, which expires in 2000. Covance is investigating 
extensions of both leases and other options with respect to such facilities. 
Covance leases its 51,000 square-foot pharmaceutical laboratory in Geneva, 
Switzerland, which lease expires in 2000. Covance's domestic packaging 
operations are conducted from several leased facilities. The principal 
packaging facility is in Allentown, Pennsylvania. The leases are for 
approximately 100,000 square feet of space and they all expire in 1999. 
Covance is currently reviewing facility needs for its domestic packaging 
operations. Covance's Swiss based packaging operation currently conducts 
business in a 20,000 sq. ft. leased facility, but has plans to construct a 
new, purpose designed 37,000 sq. ft. facility. The new facility is expected 
to be completed in early 1998. In addition, in October 1996, Covance 
purchased an 81,000 sq. ft. former pharmaceutical manufacturing facility in 
Horsham, England. After its renovation is completed by mid-1997, this 
facility will be used to provide clinical packaging, clinical and 
periapproval services and health economics services and also serve as 
Covance's European headquarters. Covance Biotechnology's facility in North 
Carolina is leased. See "Risk Factors--Risks Relating to Covance-- 
Biomanufacturing--New Business Venture." Covance also owns or leases other 
facilities in the United States, England, Ireland, Belgium, France, Germany, 
Switzerland, Sweden, Australia, Singapore and Japan. 

Legal Proceedings 

  Covance is party to lawsuits and administrative proceedings incidental to 
the normal course of its business. Covance does not believe that any 
liabilities related to such lawsuits or proceedings will have a material 
effect on its financial condition or results of operations. 

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                            MANAGEMENT OF COVANCE 

Management 
   
  Directors. Certain information with respect to the persons who will serve as 
directors of Covance following the Distributions is set forth below. Prior to 
the closing of the Covance Spin-Off Distribution, certain current directors 
will resign and the prospective directors listed below will be elected. As 
provided in the Covance Certificate, the Covance Board will be divided into 
three classes effective upon the Distributions and one class of the Covance 
Board will be elected for a three-year term at each annual meeting of 
stockholders. Included in the information set forth below are the names of 
the directors of each class and their original terms. The Covance Board will 
be comprised of eight directors, one of whom will be an officer of Covance 
and two of whom will be officers of Corning. Covance does not intend to hold 
an annual meeting of stockholders until the Spring of 1998. 


 Name                     Age    Year Term Expires 
- -----                     ---    ----------------- 
Christopher A. Kuebler     43 
Van C. Campbell            58 
William C. Ughetta         63 
J. Randall MacDonald       48 
Nigel Morris               37 
Robert M. Baylis           58 
Irwin Lerner               66 
    

   Christopher A. Kuebler has been Covance's President and Chief Executive 
Officer, and an Executive Vice President of CLSI, an affiliate of Covance, 
since November 1994. From March 1993 through November 1994, he was the 
Corporate Vice President, European Operations for Abbott Laboratories Inc. 
("ALI"), a diversified health care company. From January 1991 until March 
1993, Mr. Kuebler was the Vice President, Sales and Marketing for ALI's 
Pharmaceutical Division. Mr. Kuebler has been a member of the Covance Board 
since November 1994. Mr. Kuebler also serves in various executive officer and 
director capacities of Covance's subsidiaries. 

   Van C. Campbell is the Vice Chairman of Corning, which he joined in 1964. 
He was elected assistant treasurer in 1971, treasurer in 1972, a vice 
president in 1973, financial vice president in 1975 and senior vice president 
for finance in 1980. He became general manager of the Consumer Products 
Division in 1981. Mr. Campbell was elected vice chairman and a director in 
1983 and during 1995 was appointed to the additional position of chairman of 
Corning Life Sciences, Inc. Mr. Campbell has been a member of the Covance 
Board since May 1995. He is a director of Armstrong World Industries, Inc. 
and General Signal Corporation. 

   William C. Ughetta is the Senior Vice President and General Counsel of 
Corning. Mr. Ughetta joined Corning in 1968 as assistant secretary and 
assistant counsel. He was elected secretary of the corporation in 1971 and 
vice president in 1972. He was elected a senior vice president in 1983. Mr. 
Ughetta has been a member of the Covance Board since July 1996. He is a 
director of Siecor Corporation and Chemung Canal Trust Company. 
   
   J. Randall MacDonald has been the Senior Vice President-Human Resources 
and Administration for the GTE Corporation, a telecommunications company, 
since April 1995. Prior to April 1995, Mr. MacDonald held various senior 
positions with GTE, including Vice President-Employee Relations and 
Organizational Development (from 1988) and Vice President of Organizational 
Development (from 1986). Mr. MacDonald joined GTE in 1983 as a Director of 
Employee Relations. 

   Nigel W. Morris has been the President and Chief Operating Officer of 
Capital One Financial Corporation ("Capital One"), a financial services 
company, from July 1994 to the present. Mr. Morris was the Executive Vice 
President, Credit Card Division, of the Signet Banking Corporation 
("Signet"), from May 1993 to November 1994. From October 1988 until April 
1993, Mr. Morris was the Senior Vice President-Policy/Strategy-Credit Card 
Business for Signet. He is also a director of Capital One. 

   Robert M. Baylis was the Vice Chairman of CS First Boston Corporation 
("First Boston"), a financial services company, from March 1992 to March 
1996. Prior to March 1992, Mr. Baylis held a variety of positions with First 
Boston, including Chairman and Chief Executive Officer of CS First Boston 
Pacific, Inc./Hong Kong, Managing Director-Investment Banking Group and 
Managing Director-Equity Security Department. Prior to his retirement, Mr. 
Baylis was with First Boston for over 33 years. He is also a director of the 
following corporations: Host Marriott Corporation, Gryphon Holdings, Inc., 
Home State Holdings, Inc. and New York Life Insurance Company. 
    
                                     147 
<PAGE> 
   
   Irwin Lerner was the Chairman of the Board of Directors and Executive 
Committee of Hoffmann-La Roche, Inc. ("Roche"), a pharmaceutical company, 
from January to September 1993. From April 1980 to January 1993, Mr. Lerner 
was the President and Chief Executive Officer of Roche. He is also a director 
of the following corporations: Humana, Inc., Medarex, Inc., Public Service 
Enterprise Group Incorporated and Sequence Therapeutics, Inc. 
    
   Directors' Compensation. Each director of Covance, other than a director 
who is an employee of Covance, will receive $15,000 annually for service as a 
director and will also be paid $1,000 for each meeting of the Covance Board 
and $500 for each meeting of any committee thereof which he attends. 
   
   Covance has adopted, effective the Distribution Date, a deferred 
compensation plan for directors pursuant to which each director may elect to 
defer until a date specified by him receipt of all or a portion of his 
compensation. Such plan provides that amounts deferred may be allocated to 
(i) a cash account upon which amounts deferred may earn interest, compounded 
quarterly, at the base rate of Citibank, N.A. in effect on certain specified 
dates, (ii) a market value account, the value of which will be based upon the 
market value of Covance Common Stock from time to time, or (iii) a 
combination of such accounts. As of the Distribution Date, it is anticipated 
that there will be seven non-employee directors eligible to participate in 
the deferred compensation plan. 
    
   Covance has adopted, effective the Distribution Date, a restricted stock 
plan for non-employee directors, pursuant to which Covance will issue to each 
non-employee director elected 200 shares of Covance Common Stock for each 
year specified in the term of service for which such director was elected, 
subject to forfeiture and restrictions on transfer, and 2,000 shares upon 
such director's election, subject to forfeiture and restrictions on transfer. 

   Committees of the Board of Directors. Prior to the Distributions, the 
Covance Board is expected to establish and designate specific functions and 
areas of oversight to an Audit Committee and a Compensation Committee (the 
"Covance Compensation Committee"). The Audit Committee will examine and 
consider matters relating to the financial affairs of Covance, including 
reviewing Covance's annual financial statements, the scope of the independent 
and internal audits and the independent auditor's letter to management 
concerning the effectiveness of Covance's internal financial and accounting 
controls. The Covance Compensation Committee will make recommendations to the 
Covance Board with respect to programs for human resource development and 
management organization and succession, determine senior executive 
compensation, consider and make recommendations to the Covance Board with 
respect to compensation matters and policies and employee benefit and 
incentive plans, administer such plans, and administer Covance's stock option 
and equity based plans and grant stock options and other rights under such 
plans. 

   Executive Officers of Covance. In addition to Mr. Kuebler, the following 
persons will serve as executive officers of Covance after the Distributions: 
   
   Richard J. Andrews (49) has been a Corporate Senior Vice President of 
Covance since July of 1996. In addition, Mr. Andrews has served as the 
President of Covance Central Laboratory Services Inc., a wholly owned 
subsidiary of Covance, since June 1994. From January 1993, Mr. Andrews has 
served as the President of Covance Central Laboratory Services S.A., a wholly 
owned subsidiary of Covance Central Laboratory Services Inc. since April 
1994. Covance Central Laboratory Services Inc. and Covance Central Laboratory 
Services S.A. provide Covance's central laboratory services. Prior to January 
1993. Mr. Andrews served in various executive capacities in Europe, including 
Worldwide Business Director, for Dupont International S.A., a multinational 
chemical and pharmaceutical company. Mr. Andrews serves as a director of several
of Covance's subsidiaries.

   Michael Giannetto (34) has been Covance's Controller since July 1996 and a 
Vice President since November 1996. From December 1992 to March 1995, Mr. 
Giannetto was the Manager of Financial Reporting and Technical Accounting for 
CLSI, an affiliate of Covance. From March 1995 to July 1996, Mr. Giannetto 
was the Business Controller for Covance. Prior to December 1992, Mr. 
Giannetto was a Senior Audit Manager for Deloitte & Touche. 

   Charles C. Harwood, Jr. (43) has been Covance's Corporate Senior Vice 
President and Chief Financial Officer since July 1996. From November 1994 to 
July 1996, Mr. Harwood was the Vice President and Chief Financial Officer. 
From May 1993 to November 1994, Mr. Harwood was Executive Director, Finance 
of Covance. From January 1993 to May 1993, Mr. Harwood was Chief Financial 
Officer and Vice President of Finance with Integrated Telecom Technologies, 
Inc. Prior to that position, he was the President of Pembroke Development 
Co., Inc., a commercial real estate development company. Mr. Harwood also 
serves as a director of Bio-Imaging, Covance Biotechnology and several of 
Covance's other subsidiaries. 
    
                                     148 
<PAGE> 
   
   Jeffrey S. Hurwitz (36) has been Covance's Corporate Senior Vice 
President, General Counsel and Secretary since July 1996. From November 1994 
to July 1996, Mr. Hurwitz was Covance's Vice President, General Counsel and 
Secretary. From October 1993 to November 1994, Mr. Hurwitz was Covance's 
General Counsel and Secretary. From May 1992 to October 1993, Mr. Hurwitz was 
an Assistant Counsel and Assistant Secretary for CLSI, an affiliate of 
Covance. From August 1991 to May 1992, Mr. Hurwitz was an Assistant Counsel 
for Corning. From February 1991 to June 1991, Mr. Hurwitz was an Associate 
with the law firm of Luskin & Stern. Prior to February 1991, Mr. Hurwitz was 
an Associate with the law firm of Shearman & Sterling. Mr. Hurwitz also 
serves as a director of Bio-Imaging, Covance Biotechnology and several of 
Covance's other subsidiaries. 

   Kim D. Lamon, M.D., Ph.D. (44) has been a Corporate Senior Vice President 
of Covance since July of 1996. In addition, Dr. Lamon has been the President 
of Covance Clinical and Periapproval Services Inc. and Covance Periapproval 
Services Inc. since May 1996. Covance Clinical and Periapproval Services 
Inc., Covance Periapproval Services Inc. and their European affiliates 
provide Covance's clinical and periapproval services. From April 1994 until 
May 1996, he was the Executive Vice President, Chief Medical Officer for 
Quest Diagnostics and Senior Vice President, Science and Technology for CLSI, 
affiliates of Covance. From July 1992 until April 1994, Dr. Lamon was Senior 
Vice President, Clinical Research and Development and Executive Medical 
Director for Rhone-Poulenc Rorer ("RPR"), a pharmaceutical company. Prior to 
July 1992, Dr. Lamon was Senior Vice President, Clinical Research and 
Regulatory Affairs at RPR. Dr. Lamon received his M.D. and Ph.D. in 
Pharmacology from Thomas Jefferson University. Since 1989, Dr. Lamon has been 
an Adjunct Assistant Professor of Pharmacology at Thomas Jefferson 
University. Dr. Lamon serves as a director of several of Covance's subsidiaries.

   James D. Utterback (41) has been Covance's Corporate Senior Vice 
President, International New Business Ventures and is also responsible for 
Covance's clinical packaging operations since August 1995. From May 1994 
until August 1995, Mr. Utterback was the Senior Vice President, Human 
Resources and Quality for CLSI. Prior to May 1994, Mr. Utterback served in 
various executive capacities, including Chief Executive Officer in South 
Africa, for RPR, a pharmaceutical company. Mr. Utterback has worked in the 
pharmaceutical industry since 1985, living in Europe, Africa and the United 
States. Mr. Utterback serves as a director of several of Covance's subsidiaries.

    Michael G. Wokasch (45) has been a Corporate Senior Vice President of
Covance since July of 1996. In addition, Mr. Wokasch has been the President of
Covance Laboratories Inc., a wholly owned subsidiary of Covance, since July
1995. Covance Laboratories Inc. and its affiliates provide Covance's preclinical
services. From January 1992 until July 1995, Mr. Wokasch served as Divisional
Vice President of Sales of ALI. From October 1991 to January 1992, Mr. Wokasch
served as Director for New Product/Marketing/Development & Scientific Relations
at ALI. Prior to October 1991, Mr. Wokasch was a Director, New Product
Development at ALI. Mr. Wokasch serves as a director of several of Covance's
subsidiaries.
    
Executive Compensation 

  Historical Compensation. The following table sets forth information with 
respect to annual and long-term compensation at rates expected to be paid by 
Covance and its subsidiaries to each of the chief executive officer and the 
four other most highly compensated executive officers (the "named executive 
officers") of Covance for services to be rendered in all capacities in fiscal 
year 1996 and such compensation paid or accrued during the years ended 
December 31, 1995 and December 31, 1994 for services rendered by each of the 
named executive officers. All references in the following tables to stock and 
stock options relate to awards of, and options to purchase, Corning Common 
Stock. 

                                     149 
<PAGE> 

                          SUMMARY COMPENSATION TABLE 
   
<TABLE>
<CAPTION>

                                                                                       Long-Term Compensation 
                                                                                       ---------------------- 
                                                        Annual Compensation                    Awards 
                                                -----------------------------------    ---------------------- 
                                                                                      Restricted   Securities 
               Name and                          Salary     Bonus     Other Annual       Stock     Underlying      All Other 
          Principal Position            Year      (1)        (2)    Compensation(3)    Awards(4)     Options   Compensation(5) 
 ------------------------------------   ----    -------    -------    -------------     ---------   ---------    ------------- 
<C>                                     <C>     <C>        <C>           <C>            <C>          <C>            <C>    
Christopher A. Kuebler,                 1996    350,000    192,500       42,447              --          --         72,043 
Chairman, President and                 1995    322,567    303,958       39,927         326,926      81,000         68,680 
Chief Executive Officer                 1994     51,667    101,679           --              --      20,000          2,140 
Richard J. Andrews, Corporate Senior    1996    232,960     93,184           --              --       4,000         15,997 
Vice President; President, Corporate    1995    222,833    176,512           --              --          --         17,445 
Covance Central 
  Laboratory Services Inc.              1994    197,635     41,000           --              --      12,000         10,466 
Kim D. Lamon, Corporate Senior          1996    323,800    178,090       31,745              --          --         56,012 
Vice President; President,              1995    309,417    160,265       29,225          89,524      60,000         58,060 
Covance Clinical and                    1994    200,000    175,625           --              --      23.000         18,534 
 Periapproval Services Inc. 
  and Covance Periapproval 
  Services Inc. 
James D. Utterback,                     1996    245,758    135,167       19,244              --          --         43,876 
Corporate Senior Vice President,        1995    237,167    104,826       19,244          70,499      24,000         41,595 
International New Business Ventures     1994    153,333    134,646           --              --      18,000         17,509 
Michael Wokasch,                        1996    208,000     93,600        3,600              --          --         17,730 
Corporate Senior Vice President;        1995    100,000     76,500           --              --      38,000          4,740 
President, Covance 
  Laboratories, Inc. 
</TABLE>
    
- ------------- 

(1) Reflects for 1996 current salaries on an annualized basis. 

(2) Reflects for 1996 projected performance-based annual cash compensation 
    awards at target levels. 

(3) Includes dividends on shares of restricted stock granted but not earned 
    within one year from date of grant and tax gross-up payments. 
   
(4) Messrs. Kuebler, Utterback, Wokasch and Dr. Lamon held an aggregate of 
    44,240, 16,316, 8,000 and 27,941 shares of restricted stock, 
    respectively, having an aggregate value on September 30, 1996 of 
    $1,725,360, $636,324, $312,000 and $1,089,699, respectively. Certain of 
    such shares, net of forfeitures, were subject to performance-based 
    conditions on vesting and are subject to forfeiture upon termination and 
    restrictions on transfer prior to stated dates. Certain other shares 
    ("Career Shares") are subject to restrictions on transfer until the 
    executive officer retires at or after age 60 and are subject to 
    forfeiture prior to age 60 in whole if such officer voluntarily 
    terminates employment with Covance and in part if such officer's 
    employment is terminated by Covance. On or prior to the Distribution Date 
    (a) all restrictions on transfer will be removed from Career Shares which 
    are no longer subject to forfeiture, except such shares held by Mr. 
    Kuebler, and all Career Shares which are subject to forfeiture conditions 
    and transfer restrictions will be forfeited; and (b) performance-based 
    shares which remain subject to forfeiture conditions and transfer 
    restrictions and Career Shares which are no longer subject to forfeiture 
    held by Mr. Kuebler will be forfeited, and in lieu thereof restricted 
    shares of Covance Common Stock will thereafter be granted pursuant to the 
    terms of the Covance Incentive Stock Plan (as defined below), which 
    shares will be subject to forfeiture conditions and transfer restrictions 
    until July 1, 1997. Dividends are paid to such individuals on all shares 
    of restricted Corning Common Stock held by them. 
    

(5) Includes the following amounts to be contributed by Covance to the 
    Covance Retirement Savings Plan (as defined below) for 1996: $6,531 for 
    Mr. Kuebler, $6,517 for Mr. Andrews, $6,000 for Dr. Lamon, $6,750 for Mr. 
    Utterback and $8,250 for Mr. Wokasch. Also includes a $12,840 automobile 
    allowance to be received by each of Messrs. Kuebler, Utterback and Dr. 
    Lamon and $9,480 to be received by each of Messrs. Andrews and Wokasch. 
    Also includes 20% of interest-free loans made by Covance to the following 
    individuals in the following amounts, together with imputed interest 
    thereon: $200,000 for Mr. Kuebler, $150,000 for Dr. Lamon 

                                     150 
<PAGE> 

    and $100,000 for Mr. Utterback, which loans are to be forgiven over a 
    five-year period provided they continue to be employed by Covance and 
    were made to assist such individuals in relocating to the New Jersey 
    area. 

  Option Grants. The following table sets forth certain information regarding 
options granted in 1995 (except for Mr. Andrews whose options were granted on 
April 25, 1996) to the named executive officers pursuant to Corning stock 
option plans. No other options were granted to the named executive officers 
in 1996. Employees of Covance who hold at the Distribution Date Corning stock 
options, including a portion of those granted on December 6, 1995, will 
receive new options of Covance ("New Options") under the Covance Stock Option 
Plan (as defined below) in exchange for the surrender of such Corning 
options. The remainder of the options granted on December 6, 1995 will be 
cancelled. It is anticipated that such cancelled options will be replaced by 
New Options to be granted under the Covance Stock Option Plan. 

   The exercise prices and the number of shares of Covance Common Stock 
subject to New Options will be determined as of the time of the Distributions 
so as to preserve the investment basis and intrinsic gain associated with the 
Corning options surrendered as of the date of the Covance Spin-Off 
Distribution. Generally, the expiration dates and the dates on which New 
Options are exercisable will be identical to those under the corresponding 
Corning options at the time of the Distributions. Certain New Options will 
provide that upon exercise of such option through the surrender of previously 
owned shares of Covance Common Stock, the participant will be entitled to 
receive options covering the same number of shares so surrendered, with an 
exercise price equal to the fair market value of the shares at the time of 
the exercise of the New Option. 

                  OPTION/SAR GRANTS IN FISCAL YEAR 1995 (1) 

<TABLE>
<CAPTION>
                                                                                  Potential Realizable Value at 
                                                                                  Assumed Annual Rates of Stock 
                                                                                      Price Appreciation for 
                                                 Individual Grants                       Option Term (3) 
                                       ------------------------------------     ----------------------------------- 
                           Number of     % of Total 
                          Securities      Options 
                          Underlying      Granted 
                            Options     to Employees                            Gain 
                            Granted      in Fiscal     Exercise   Expiration     at        Gain at       Gain at 
          Name                (2)           Year         Price       Date      0% (4)        5%            10% 
- -----------------------    ---------    ------------   -------     ---------   ------     ----------   ------------ 
<C>                           <C>            <C>         <C>      <C>  <C>        <C>     <C>            <C>       
Christopher A. Kuebler        81,000         2.4%        31.25    12/5/2005       0       1,591,890      4,034,161 
Richard J. Andrews             4,000         0.1%        34.44    4/24/2006       0          86,637        219,554 
Kim D. Lamon                  60,000         1.8%        31.25    12/5/2005       0       1,179,177      2,988,267 
James D. Utterback            24,000         0.7%        31.25    12/5/2005       0         471,671      1,195,307 
Michael Wokasch               30,000         0.9%        31.25    12/5/2005       0         589,589      1,494,134 
                               8,000         0.2%        27.50    10/3/2005       0         138,357        350,623 
All Optionees as a 
  Group (4)                3,389,100       100.0%        31.34         2005       0      66,797,662    169,278,390 
</TABLE>
- ------------- 

(1) No SARs were granted. 

(2) The stock option agreements with Messrs. Kuebler, Utterback and Wokasch 
    (with respect to the 30,000 share grant) and Dr. Lamon provide that 
    one-half of the options will become exercisable on February 1, 1999 and 
    all options will become exercisable on February 1, 2000. The stock option 
    agreement with Mr. Andrews provides that one-half of the options become 
    exercisable on April 24, 1997 and all of the options will become 
    exercisable on April 24, 1998. The stock option agreement with Mr. 
    Wokasch (with respect to the 8,000 share grant) provides that one-half of 
    the options become exercisable on October 4, 1996 and all of the options 
    will become exercisable on October 4, 1997. All such agreements also 
    provide that an additional option may be granted when the optionee uses 
    shares of Corning Common Stock to pay the purchase price of an option. 
    The additional option will be exercisable for the number of shares 
    tendered in payment of the option price, will be exercisable at the then 
    fair market value of the Corning Common Stock, will become exercisable 
    only after the lapse of twelve months and will expire on the expiration 
    date of the original option. 

(3) The dollar amounts set forth under these columns are the result of 
    calculations at 0% and at the 5% and 10% rates established by the 
    Commission and therefore are not intended to forecast future appreciation 
    of Corning's stock price. 
   
(4) No gain to the optionees is possible without an appreciation in stock 
    price, an event which will also benefit all stockholders. If the stock 
    price does not appreciate, the optionees will realize no benefit. 
    


                                     151 
<PAGE> 

  Option Exercises and Fiscal Year-End Values. The following table sets forth 
the number of shares of Corning Common Stock covered by both exercisable and 
unexercisable stock options as of December 31, 1995, for the named executive 
officers. The named executive officers exercised no options in 1996. 

                  AGGREGATED OPTION/SAR EXERCISES IN FISCAL 
           YEAR 1995 AND 1995 FISCAL YEAR-END OPTION/SAR VALUES (1) 

<TABLE>
<CAPTION>

                                                            Number of Securities 
                                                           Underlying Unexercised            Value of Unexercised 
                                                                 Options at                  In-the-Money Options 
                                                              Fiscal Year End                 At Fiscal Year End 
                                                        ----------------------------     ------------------------------ 
                               Shares 
                              Acquired       Value 
          Name              on Exercise     Realized    Exercisable    Unexercisable    Exercisable     Unexercisable 
- ------------------------    ------------    --------    -----------    -------------     -----------    --------------- 
<C>                              <C>           <C>        <C>             <C>                <C>           <C>    
Christopher A. Kuebler           0             0          10,000          91,000             0                  0 
Richard J. Andrews               0             0           2,000          14,000             0                  0 
Kim D. Lamon                     0             0          10,000          73,000             0             13,812 
James D. Utterback               0             0          10,000          32,000             0              8,500 
Michael Wokasch                  0             0               0          38,000             0             28,501 
</TABLE>

- ------------- 
(1) There are no SARs outstanding. 

  Corporate Performance Plan Activity. Awards of performance-based shares of 
Corning Common Stock have been granted to Covance's executive officers 
pursuant to a series of performance-based plans (the "Corporate Performance 
Plan"). The Corporate Performance Plan provides the mechanisms to reward 
improvement in corporate performance as measured by net income, earnings per 
share and/or return on equity. Each year minimum, target and maximum goals 
are set and shares awarded (at target levels) which are subject to forfeiture 
in whole or in part if performance goals are not met. The percentage of 
awards that may be earned ranges from 0% to 150% of target. Shares earned 
remain subject to forfeiture and restrictions on transfer for two years 
following the end of the performance period. 
  The following table sets forth the number of performance-based shares 
awarded under the Corporate Performance Plan. The dollar value of shares 
earned for 1995 is reflected in the "Restricted Stock Awards" column of the 
Summary Compensation Table appearing on page 137. 

   In late 1996, the Compensation Committee of the board of directors of 
Corning (the "Corning Board") will assess performance against goals, 
determine the number of shares earned of those granted in December 1995 and 
remove all possibility of forfeiture and restrictions on transfer from such 
shares. 

                  CORPORATE PERFORMANCE PLAN ACTIVITY TABLE 
<TABLE>
<CAPTION>

                                             Number                                Number 
                                               of                      Number        of           Vesting 
                                   Grant     Shares    Performance    of Shares    Shares         Date of 
         Number             Year    Date    Granted       Period      Forfeited    Earned      Earned Shares 
- ------------------------   ----    -----    --------    ----------    ---------   --------     --------------- 
<C>                         <C>    <C>       <C>           <C>        <C>          <C>              <C>  
Christopher A. Kuebler      1996   12/95     13,500        1996                                     2/99 
                            1995   12/94     10,000        1995                    10,740           2/98 
                            1994                  0 
Richard J. Andrews          1996                  0 
                            1995                  0 
                            1994                  0 
Kim D. Lamon                1996   12/95     10,000        1996                                     2/99 
                            1995   12/94      6,500        1995         3,559       2,941           2/98 
                            1994                  0 
James D. Utterback          1996   12/95      4,000        1996                                     2/99 
                            1995   12/94      4,000        1995         1,684       2,316           2/98 
                            1994                  0 
Michael Wokasch             1996   12/95      5,000        1996                                     2/99 
                            1995                  0 

</TABLE>

                                     152 
<PAGE> 

  Variable Compensation. Covance has adopted, effective upon the 
Distributions, a variable compensation plan (the "Plan"), an annual incentive 
cash compensation plan for approximately 400 supervisory, management and 
executive employees similar to an annual performance plan currently 
maintained by Covance. The terms of the Plan are as follows. 

  The performance-based annual cash incentive awards payable under the Plan 
will be grounded in financial goals such as net income, operating margin, 
return on equity, or earnings per share, or a combination thereof, and 
quantifiable non-financial goals. Each participant will be assigned a target 
award, as a percentage of base salary in effect at the end of the performance 
year for which the target is set, payable if the target is achieved. Actual 
results will be compared to the scale of targets with each gradation of 
desired result corresponding to a percentage which will be multiplied by the 
employee's assigned target award. If the actual result is below target, 
awards will be less than target, down to a point below which no awards are 
earned. If the desired result is above target, awards will be greater than 
target, up to a stated maximum award. The maximum award assigned to the chief 
executive officer may not exceed 200% of base salary in effect on the date 
the Covance Compensation Committee sets the target for the performance year. 
The Covance Compensation Committee retains the right to reduce any award if 
it believes individual performance does not warrant the award calculated by 
reference to the result. 

  Employee Equity Participation Program. Covance has adopted, effective upon 
the Distributions, the Employee Equity Participation Program (the "Program") 
consisting of two plans: (a) a stock option plan (the "Covance Stock Option 
Plan") and (b) an incentive stock plan (the "Covance Incentive Stock Plan"). 
The Program is designed to provide a flexible mechanism to permit key 
employees of Covance and of any subsidiary to obtain significant equity 
ownership in Covance, thereby increasing their proprietary interest in the 
growth and success of Covance. 

  The Program, which will be administered by the Covance Compensation 
Committee, provides for the grant to eligible employees of either 
non-qualified or "incentive stock" options, or both, to purchase shares of 
Covance Common Stock at no less than fair market value on the date of grant. 
The Covance Compensation Committee may also provide that options may not be 
exercised in whole or in part for any period or periods of time; provided, 
however, that no option will be exercisable until at least twelve months from 
the date of grant. All options shall expire not more than ten years from the 
date of grant. Options will not be assignable or transferable except for 
limited circumstances on death. During the lifetime of the employee an option 
may be exercised only by him. The option price must be paid to Covance by the 
optionee in full prior to delivery of the stock. The optionee may pay the 
option price in cash or with shares of Covance Common Stock owned by him. The 
optionee will have no rights as a stockholder with respect to the shares 
subject to option until shares are issued upon exercise of the option. The 
Covance Compensation Committee may grant options pursuant to which an 
optionee who uses shares of Covance Common Stock to pay the purchase price of 
an option will receive automatically on the date of exercise an additional 
option to purchase shares of Covance Common Stock. Such additional option 
will cover the number of shares tendered in payment of the option price, will 
be exercisable at the then fair market value of Covance Common Stock, will 
become exercisable only after the lapse of twelve months and will expire on 
the expiration date of the original option. 

  The Program also authorizes the Covance Compensation Committee to award to 
eligible employees shares, or the right to receive shares, of Covance Common 
Stock, the equivalent value in cash or a combination thereof (as determined 
by the Covance Compensation Committee). The Covance Compensation Committee 
shall determine the number of shares which are to be awarded to individual 
employees and the number of rights covering shares to be issued upon 
attainment of predetermined performance objectives for specified periods. The 
shares awarded directly to individual employees may be made subject to 
certain restrictions prohibiting sale or other disposition and may be made 
subject to forfeiture in certain events. Shares may be issued to recognize 
past performance either generally or upon attainment of specific objectives. 
Shares issuable for performance (based upon specific predetermined 
objectives) will be payable only to the extent that the Covance Compensation 
Committee determines that an eligible employee has met such objectives and 
will be valued as of the date of such determination. Upon issuance, such 
shares may (but need not) be made subject to the possibility of forfeiture or 
certain restrictions on transfer. 

  Key executive, managerial and technical employees (including officers and 
employees who are directors) of Covance and of any subsidiary will be 
eligible to participate in the Program and the plans thereunder. The 
selection of employees eligible to participate in any plan under the Program 
is within the discretion of the Covance 

                                     153 
<PAGE> 

Compensation Committee. Approximately 400 employees would have been eligible 
to participate in the plans under the Program had the Program been in effect 
in 1996. 
   
  Under the Program, the maximum number of shares of Covance Common Stock 
which may be optioned or granted to eligible employees will be 6,000,000. 
Shares from expired or terminated options under the Covance Stock Option Plan 
will be available again for option grant under the Program. Shares which are 
issued but not earned, or which are forfeited under the Covance Incentive 
Stock Plan, will be available again for issuance under the Program. The 
Program provides for appropriate adjustments in the aggregate number of 
shares subject to the Program and in the number of shares and the price per 
share, or either, of outstanding options in the case of changes in the 
capital stock of Covance resulting from any recapitalization, stock or 
unusual cash dividend, stock distribution, stock split or any other increase 
or decrease effected without receipt of consideration by Covance, or a merger 
or consolidation in which Covance is the surviving corporation. 
    
  The Program has a term of five years and no shares may be optioned or 
awarded and no rights to receive shares may be granted after the expiration 
of the Program. The Covance Board is authorized to terminate or amend the 
Program, except that it may not increase the number of shares available 
thereunder, decrease the price at which options may be granted, change the 
class of employees eligible to participate, or extend the term of the Program 
or options granted thereunder without the approval of the holders of a 
majority of the outstanding shares of Covance Common Stock. 
   
  Covance believes that the U.S. federal income tax consequences of the 
Program are as follows. An optionee who exercises a non-qualified option 
granted under the Covance Stock Option Plan will recognize compensation 
taxable as ordinary income (subject to withholding) in an amount equal to the 
difference between the option price and the fair market value of the shares 
on the date of exercise and Covance or the subsidiary employing the optionee 
will be entitled to a deduction from income in the same amount. The 
optionee's basis in such shares will be increased by the amount taxable as 
compensation, and his capital gain or loss when he disposes of the shares 
will be calculated using such increased basis. 
    
  If all applicable requirements of the Code with respect to incentive stock 
options are met, no income to the optionee will be recognized and no 
deduction will be allowable to Covance at the time of the grant or exercise 
of an incentive stock option. The excess of the fair market value of the 
shares at the time of exercise of an incentive stock option over the amount 
paid is an item of tax preference which may be subject to the alternative 
minimum tax. In general, if an incentive stock option is exercised three 
months after termination of employment, the optionee will recognize ordinary 
income in an amount equal to the difference between the option price and the 
fair market value of the shares on the date of exercise and Covance or the 
subsidiary employing the optionee will be entitled to a deduction in the same 
amount. If the shares acquired subject to the option are sold within one year 
of the date of exercise or two years from the date of grant, the optionee 
will recognize ordinary income in an amount equal to the difference between 
the option price and the lesser of the fair market value of the shares on the 
date of exercise or the sale price and Covance or the employing subsidiary 
will be entitled to a deduction from income in the same amount. Any excess of 
the sale price over the fair market value on the date of exercise will be 
taxed as a capital gain. 

  Shares of Covance Common Stock which are not subject to restrictions and 
possibility of forfeiture and which are awarded to an employee under the 
Covance Incentive Stock Plan will be treated as ordinary income, subject to 
withholding, to an employee at the time of the transfer of the shares to him 
and the value of such awards will be deductible by Covance or by the 
subsidiary employing the employee at the same time in the same amount. Shares 
granted subject to restrictions and possibility of forfeiture will not be 
subject to tax nor will such grant result in a tax deduction for Covance at 
the time of award. However, when such shares become free of restrictions and 
possibility of forfeiture, the fair market value of such shares at that time 
(i) will be treated as ordinary income to the employee and (ii) will be 
deductible by Covance or by the subsidiary employing the employee. 

  The tax treatment upon disposition of shares acquired under the Program will 
depend upon how long the shares have been held and on whether or not the 
shares were acquired by exercising an incentive stock option. There are no 
tax consequences to Covance upon a participant's disposition of shares 
acquired under the Program, except that Covance may take a deduction equal to 
the amount the participant must recognize as ordinary income in the case of 
the disposition of shares acquired under incentive stock options before the 
applicable holding period has been satisfied. 

                                     154 
<PAGE> 

  Pension Plans. None of the executive officers of Covance are currently 
active participants in a qualified defined benefit plan of Covance. 

  It is anticipated that, prior to the Distribution Date, the Compensation 
Committee of the Corning Board will approve, and Covance will adopt, a 
nonqualified Covance Supplemental Executive Retirement Plan for the benefit 
of certain executive officers of Covance, including the named executive 
officers, after the Distribution Date. Once adopted, it is anticipated that 
such plan will be, in whole or in part, an unfunded, unsecured obligation of 
Covance and administered by the Covance Compensation Committee. 

  Eligible executives may commence receiving full benefits under the plan upon 
attaining age 60, so long as they have completed at least twenty years of 
service with Corning or any subsidiary thereof. Retirement benefits to be 
provided under the plan will be based on 40% of an executive's "Final Average 
Pay," defined to mean the average of an executive's base salary plus bonus, 
taking into account the highest five consecutive years of the executive's 
last ten years of employment with Corning or any subsidiary thereof. Under 
the terms of the plan, executives may, with the approval of the Covance 
Compensation Committee, elect to commence receiving reduced benefits prior to 
age 60, provided that they have completed at least five years of service with 
Corning or any subsidiary thereof and have attained age 55. Benefits 
commencing prior to age 60 will be reduced by 5% of the amount of benefits 
earned for each year prior to age 60. For example, at age 55, an executive 
with at least twenty years of service may be eligible to receive 30% of Final 
Average Pay so long as the executive receives approval from the Covance 
Compensation Committee. 

  At retirement, the normal form of payment under the plan will be monthly 
payments over the lifetime of the executive (or actuarially reduced joint and 
survivor benefits over the joint lives of the executive and a named 
beneficiary). Alternatively, the executive may elect under the plan, subject 
to the approval of the Covance Compensation Committee, the right to receive 
an actuarially determined lump-sum distribution from the plan. 

  Maximum annual benefits, based on at least twenty years of service and the 
Final Average Pay calculated under the straight life annuity option form of 
pension, payable to participants at ages 55 to 60 are illustrated in the 
table set forth below. The table below does not reflect any limitations on 
benefits imposed by ERISA. 


<TABLE>
<CAPTION>
                                 Age (With at least 20 Years of Service) 
                      -------------------------------------------------------------- 
Final Average Pay       55         56         57        58         59          60 
 -----------------   -------    -------    -------    -------   -------    --------- 
<C>                   <C>       <C>        <C>        <C>       <C>         <C>    
$ 100,000              30,000    32,000     34,000     36,000    38,000      40,000 
  200,000              60,000    64,000     68,000     72,000    76,000      80,000 
  300,000              90,000    96,000    102,000    108,000   114,000     120,000 
  400,000             120,000   128,000    136,000    144,000   152,000     160,000 
  500,000             150,000   160,000    170,000    180,000   190,000     200,000 
  600,000             180,000   192,000    204,000    216,000   228,000     240,000 
  700,000             210,000   224,000    238,000    252,000   266,000     280,000 
  800,000             240,000   256,000    272,000    288,000   304,000     320,000 
  900,000             270,000   288,000    306,000    324,000   342,000     360,000 
1,000,000             300,000   320,000    340,000    360,000   380,000     400,000 
1,100,000             330,000   352,000    374,000    396,000   418,000     440,000 
1,200,000             360,000   384,000    408,000    432,000   456,000     480,000 
</TABLE>

  Covance Retirement Savings Plan. Most of the employees of Covance and its 
subsidiaries have been eligible to participate in a tax-qualified, defined 
contribution plan known as the Covance Retirement Savings Plan (the "Covance 
Retirement Savings Plan" to be renamed the "Covance Stock Purchase Savings 
Plan" prior to the Distribution Date), which provides for investment of 
employee contributions, including tax-deferred contributions under Section 
401(k) of the Code, and matching contributions made by their employers, in 
several investment funds, including Corning Common Stock, at the employees' 
discretion. Effective as of the Distribution Date, Covance Common Stock will 
be added as an investment fund and all or a portion of the employer matching 
contributions will automatically be invested in Covance Common Stock. Corning 
Common Stock will no longer be available as an investment fund except with 
respect to amounts already so invested under the Covance Retirement Savings 
Plan. 

  Effective as of the Distribution Date, the Covance Retirement Savings Plan 
will be amended to permit participating employees' employers to make 
discretionary contributions, other than matching contributions, to the 
Covance Retirement Savings Plan for the benefit of such employees, which 
contributions may be invested in Covance Common Stock. 

                                     155 
<PAGE> 

  Covance Employee Stock Ownership Plan. Covance has adopted, effective upon 
the Distributions, an employee stock ownership plan, as defined in Section 
4975(e)(7) of the Code and related regulations and intended to qualify as a 
retirement plan under Section 401(a) of the Code, to be known as the Covance 
Employee Stock Ownership Plan (the "Covance ESOP"). 

  Individuals who are active employees of Covance and its U.S. subsidiaries as 
of the Distribution Date will become participants in the Covance ESOP. To the 
extent permitted under the Covance ESOP, Covance will contribute as of the 
Distribution Date an amount equal to a portion of each participating 
employee's annual compensation. Covance may in its discretion from time to 
time make additional contributions to the Covance ESOP for the benefit of 
participating employees. The assets of the Covance ESOP will be invested 
primarily in shares of Covance Common Stock. 

  Amounts contributed to the Covance ESOP for the benefit of participating 
employees will be 100% vested on the earlier of death, disability or the 
second anniversary of the effective date of the grant. Contributions to the 
Covance ESOP will not currently be taxable income to the participating 
employees and will not generally be available to them until termination of 
employment. 

  Covance Restricted Share Plan. Covance has adopted, effective upon the 
Distributions, the Covance Restricted Share Plan, intended to provide to 
Covance's foreign national employees in its non-U.S. locations who otherwise 
are ineligible to participate in the Covance ESOP and to domestic employees 
whose participation therein is subject to limitations imposed by ERISA 
benefits similar to the Covance ESOP. To the extent permitted under the plan, 
Covance will award to participating employees shares of Covance Common Stock 
as of the Distribution Date, the market value of which shall equal a portion 
of such employee's annual compensation. Covance may in its discretion from 
time to time make additional awards to participating employees. Shares of 
Covance Common Stock awarded to participating employees will be 100% vested 
on the earlier of death, disability or the second anniversary of the date of 
each grant. 

  Covance Stock Purchase Plan. Covance has adopted, effective upon the 
Distributions, the Covance Stock Purchase Plan (the "Covance Stock Purchase 
Plan") pursuant to which Covance may make available for sale to employees 
shares of its Common Stock at a price equal to 85% of the market value on the 
first or last day of each calendar quarter, whichever is lower. 

  The Covance Stock Purchase Plan, which will be administered by the Covance 
Compensation Committee, is designed to give eligible employees (generally, 
employees of Covance and its U.S. subsidiaries) the opportunity to purchase 
shares of Covance Common Stock through payroll deductions up to 10% of 
compensation in a series of quarterly offerings commencing January 1, 1997, 
and ending no later than December 31, 2006. 

  Any eligible employee may elect to participate in the Covance Stock Purchase 
Plan on a quarterly basis and may terminate his payroll deduction at any time 
or increase or reduce prospectively the amount of his deduction at the 
beginning of any calendar quarter. At the end of each calendar quarter, a 
participating employee will purchase shares of Covance Common Stock with the 
funds deducted. The number of shares purchased will be a number determined by 
dividing the amount withheld by the lower of 85% of the closing price of a 
share of Covance Common Stock as reported in The Wall Street Journal on the 
first or last business day of the particular calendar quarter. An employee 
will have no interest in any shares of Covance Common Stock until such shares 
are actually purchased by him. 

  Under the Covance Stock Purchase Plan, the maximum number of shares of 
Covance Common Stock which may be purchased by eligible employees will be 
1,000,000, subject to adjustment in the case of changes in the capital stock 
of Covance resulting from any recapitalization, stock dividend, stock split 
or any other increase or decrease effected without receipt of consideration 
by Covance or a merger or consolidation in which Covance is the surviving 
corporation. 

  The Covance Stock Purchase Plan has a term of ten years and no shares of 
Covance Common Stock may be offered for sale or sold under the Covance Stock 
Purchase Plan after the tenth anniversary of the effective date. The Covance 
Board is authorized to terminate or amend the Covance Stock Purchase Plan, 
except that it may not increase the number of shares of Covance Common Stock 
available thereunder, decrease the price at which such shares may be offered 
for sale or extend the term of the Covance Stock Purchase Plan without the 
approval of the holders of a majority of the shares of the capital stock of 
Covance cast at a meeting at which such matter is considered. 

                                     156 
<PAGE> 
   
  Employment Agreements; Severance and Change in Control Arrangements. It is 
anticipated that Mr. Kuebler will enter into an employment agreement with 
Covance. The agreement will expire on or before the third anniversary of the 
Distribution Date. The agreement will include provisions for an annual salary 
of no less than $450,000, with increases subject to the discretion of the 
Covance Board; annual target participation in the Variable Compensation Plan 
of Covance in amounts no less than 65% of annual salary in effect at the time 
performance goals are established; and severance payments following a 
termination or a change in control in accordance with the severance policy 
described below, except that Mr. Kuebler will receive three times his base 
annual salary and three times his annual award of variable compensation in 
the event of termination for reasons other than cause. 

  On or before the Distribution Date, Covance will adopt a severance policy 
pursuant to which it will provide to each executive officer, including the 
named executive officers, compensation equal to two times the executive 
officer's base annual salary at the annual rate in effect on the date of 
termination and two times the annual award of variable compensation at the 
most recent target level in the event that such executive officer has been 
terminated for reasons other than cause. Such executive officer will also be 
entitled to participate in Covance's health and benefits plans (to the extent 
permitted by the administrative provisions of such plans and applicable 
federal and state law) for a period of up to two years or until such officer 
is covered by a successor employer's benefit plans, whichever first occurs. 
Pursuant to such policy, Covance will also provide to each executive officer 
upon the termination of employment by Covance other than for cause following 
a change in control of Covance compensation equal to three times base annual 
salary in effect on the termination date and three times the annual variable 
compensation at the most recent target level and such officer will be 
entitled to participate in Covance's health and benefits plans for a period 
of up to three years. A "change in control" is defined in the policy to 
include the following: the acquisition by a person of 20% or more of the 
voting stock of Covance; as a result of a contested election a majority of 
the Covance Board members are different than the individuals who served on 
Covance's Board in the two years prior to such contested election; or 
approval by Covance's shareholders of a merger or consolidation in which 
Covance is not the survivor thereof, or a sale or disposition of all or 
substantially all of Covance's assets or a plan of partial or complete 
liquidation. 
    
                                     157 
<PAGE> 

                        SECURITY OWNERSHIP BY CERTAIN 
                 BENEFICIAL OWNERS AND MANAGEMENT OF COVANCE 

   
  All of the outstanding shares of Covance Common Stock are currently held by 
Quest Diagnostics. The following table sets forth the number of shares of 
Covance Common Stock that are projected to be beneficially owned after the 
Covance Spin-Off Distribution by the directors, by the named executive 
officers and by all directors and executive officers of Covance as a group. 
The projections are based on the number of shares of Corning Common Stock 
held by such persons and such group as of September 30, 1996 (excluding 
Career Shares that will be forfeited prior to the Distribution Date and 
Corning Common Stock held in the Covance Retirement Savings Plan and the 
Corning Investment Plans) and on the number of options to acquire Corning 
Common Stock held as of such date and exercisable within 60 days thereof. 
With respect to the shares of Covance Common Stock, the number reflects the 
distribution ratio of one share of Covance Common Stock for every four shares 
of Corning Common Stock and with respect to options the number reflects the 
actual number of shares of Corning Common Stock subject to options. The stock 
options held by the directors and executive officers of Covance will not 
affect the security ownership of Covance unless (i) such options are 
exercised prior to the Record Date and the underlying shares of Corning 
Common Stock are held on the Record Date or (ii) such options are converted 
into options to purchase shares of Covance Common Stock. 


                                  Number of Shares             Number of 
Name                           Beneficially Owned (1)     Exercisable Options 
- ---------------------------     -----------------------    ------------------- 
Richard J. Andrews                                                4,000 
Robert M. Baylis                                                      0 
Van C. Campbell                                                 132,457 
Christopher A. Kuebler                                           20,000 
Kim D. Lamon                                                     10,000 
Irwin Lerner                                                          0 
J. Randall MacDonald                                                  0 
Nigel Morris                                                          0 
William C. Ughetta                                               44,000 
James D. Utterback                                               10,000 
Michael Wokasch                                                   4,000 

All Directors and Executive 
 Officers as a Group                                            227,957 

    
- ------------- 
(1) Does not include      shares owned by the spouses and minor children of 
    certain executive officers and directors as to which such officers and 
    directors disclaim beneficial ownership. 

                                     158 
<PAGE> 

                     DESCRIPTION OF COVANCE CAPITAL STOCK 

General 

  The following is a brief summary of certain provisions of the Covance 
Certificate, as the restated certificate of incorporation will be amended 
immediately prior to the Covance Spin-Off Distribution, and does not relate 
to or give effect to provisions of statutory or other law except as 
specifically stated. The Covance Certificate authorizes the issuance of 
140,000,000 shares of Covance Common Stock. Approximately 56,903,469 shares 
of Covance Common Stock are expected to be outstanding immediately following 
the Covance Spin-Off Distribution. The rights of holders of shares of Covance 
Common Stock are governed by the Covance Certificate, the Covance By-Laws and 
by the DGCL. 

Voting Rights 

  Subject to the voting of any shares of Covance Series Preferred Stock (as 
defined below) that may be outstanding, voting power is vested in the Covance 
Common Stock, each share having one vote. 

Preemptive Rights 

  The Covance Certificate provides that no holder of shares of Covance Common 
Stock or Covance Series Preferred Stock shall have any preemptive rights 
except as the Covance Board may determine from time to time. No such rights 
have been granted by the Covance Board. 

Covance Common Stock 

  Liquidation Rights. Subject to the preferential rights of any outstanding 
Covance Series Preferred Stock, in the event of any liquidation of Covance, 
holders of shares of Covance Common Stock then outstanding are entitled to 
share ratably in the assets of Covance available for distribution to such 
holders. 
   
   Dividend Policy. Subject to any preferential rights of any outstanding 
preferred securities of Covance, such dividends as may be determined by the 
Covance Board may be declared and paid on the shares of Covance Common Stock 
from time to time out of any funds legally available therefor. Covance has no 
present intention to declare dividends for the foreseeable future. It is 
currently contemplated that, following the Distributions, Covance will not 
pay cash dividends in the foreseeable future, but will retain earnings to 
provide funds for the operation and expansion of its business. Dividend 
decisions will be based upon a number of factors, including the operating 
results and financial requirements of Covance and such other considerations 
as the Covance Board deems relevant. In addition, other than with respect to 
stock dividends, and certain purchases, repurchases or other distributions 
made pursuant to the Benefits Plans and the Rights Plan (each as defined in 
the Covance Credit Facility) the Covance Credit Facility prohibits Covance 
from paying cash dividends on the Covance Common Stock during a Default or an 
Event of Default or if after giving effect to the payment of such dividends 
Covance would not be in compliance with the financial covenants contained 
therein. See "Risk Factors--Risks Relating to Covance--Absence of Dividends" 
and "Description of Certain Indebtedness of Covance." 
    
   Other Provisions. The shares of Covance Common Stock have no redemption, 
sinking fund or conversion privileges applicable thereto and holders of 
shares of Covance Common Stock are not liable to assessments or to further 
call. 
   
   Listing and Trading. Prior to the Distributions, there has been no public 
trading market for the Covance Common Stock although a "when issued" market 
is expected to develop prior to the Distribution Date. Application will be 
made to list the Covance Common Stock on the NYSE, subject to official notice 
of the Distributions, under the trading symbol "CVD". Prices at which Covance 
Common Stock may trade prior to the Distributions on a "when-issued" basis or 
after the Distributions cannot be predicted. Until shares of the Covance 
Common Stock are fully distributed and an orderly market develops, the prices 
at which trading in such stock occurs may fluctuate significantly. The prices 
at which Covance Common Stock will trade will be determined by the 
marketplace and may be influenced by many factors, including, among others, 
the depth and liquidity of the market for Covance Common Stock, investor 
perceptions of Covance, the contract research business, and general economic 
and market conditions. Covance initially will have approximately 18,000 
stockholders of record, based on the expected number of holders of Quest 
Diagnostics Common Stock immediately following the Quest Diagnostics Spin-Off 
    
                                     159 
<PAGE> 

Distribution. The Transfer Agent and Registrar for the Covance Common Stock 
will be Harris Trust and Savings Bank. For certain information regarding 
options to purchase Covance Common Stock that may become outstanding after 
the Distributions, see "Management of Covance." 

Covance Series Preferred Stock
   
  The Covance Certificate authorizes the issuance of up to 10,000,000 shares 
of Covance Series Preferred Stock, par value $1.00 per share (the "Covance 
Series Preferred Stock"). The Covance Board has the authority to issue such 
shares from time to time, without stockholder approval, and to determine the 
designations, preferences, rights, including voting rights, and restrictions 
of such shares, subject to the DGCL. Pursuant to this authority, the Covance 
Board has designated 1,000,000 shares of Covance Series Preferred Stock as 
Covance Series A Preferred Stock. No other class of Covance Series Preferred 
Stock has been designated by the Covance Board. 
    
Preferred Share Purchase Rights 
   
  Attached to each share of Covance Common Stock is one right ("Covance 
Right"), which entitles the registered holder to purchase from Covance one 
one-hundredth of a share of Covance Series A Preferred Stock at a price of 
$100 per one-hundredth of a share of Covance Series A Preferred Stock (the 
"Exercise Price"), subject to adjustment. The Covance Rights expire on 
December 31, 2006 (the "Final Expiration Date"), unless the Final Expiration 
Date is extended or unless the Covance Rights are earlier exercised. 
    
   The Covance Rights represented by the certificates for shares of Covance 
Common Stock are not exercisable, and are not transferable apart from the 
shares of Covance Common Stock, until the earlier of (1) ten days following 
the public announcement by Covance or an Acquiring Person (as defined below) 
that a person or group has acquired beneficial ownership of 20% or more of 
the shares of Covance Common Stock (an "Acquiring Person") or (2) ten 
business days (or such later date as the Covance Board may determine prior to 
such time as any person or group of affiliated persons becomes an Acquiring 
Person) after the commencement or first public announcement of an intention 
to make a tender or exchange offer that would result in a person or group 
beneficially owning 20% or more of the shares of Covance Common Stock (the 
earlier of such dates being called the "Rights Distribution Date"). The 
Covance Board has the authority to determine that a person that has 
inadvertently acquired beneficial ownership of 20% of the shares of Covance 
Common Stock is not an Acquiring Person if such person promptly reduces its 
ownership interest to below 20%. Separate certificates for the Covance Rights 
will be mailed to holders of record of the shares of Covance Common Stock as 
of such date. The Covance Rights could then begin trading separately from the 
shares of Covance Common Stock. 

   Generally, in the event that a person or group becomes an Acquiring 
Person, each Covance Right (other than the Covance Rights owned by the 
Acquiring Person and certain affiliated persons) will thereafter entitle the 
holder to receive, upon exercise of the Covance Right, shares of Covance 
Common Stock having a value equal to two times the Exercise Price of the 
Covance Right. In the event that a person or group becomes an Acquiring 
Person (but prior to such time as such person or group beneficially owns 50% 
or more of the outstanding shares of Covance Common Stock), the Covance Board 
may exchange each Covance Right and each one one-hundredth of a share of 
Covance Series A Preferred Stock (other than Covance Rights and Covance 
Series A Preferred Stock owned by the Acquiring Person and certain affiliated 
persons) for one share of Covance Common Stock. In the event that Covance is 
acquired in a merger, consolidation, or other business combination 
transaction or more than 50% of Covance's assets, cash flow or earning power 
is sold or transferred, each Covance Right (other than the Covance Rights 
owned by an Acquiring Person and certain affiliated persons) will thereafter 
entitle the holder thereof to receive, upon the exercise of the Covance 
Right, common stock of the acquiring corporation having a value equal to two 
times the Exercise Price of the Covance Right. 
   
   The Covance Rights are redeemable in whole, but not in part, at $.01 per 
Covance Right at any time prior to any person or group becoming an Acquiring 
Person. The right to exercise the Covance Rights terminates at the time that 
the Covance Board elects to redeem the Covance Rights. Notice of redemption 
shall be given by mailing such notice to the registered holders of the 
Covance Rights. At no time will the Covance Rights have any voting rights. 
The Covance Rights Agent is Harris Trust and Savings Bank (the "Covance 
Rights Agent"). 
    
   The exercise price payable, and the number of shares of Covance Series A 
Preferred Stock or other securities or property issuable, upon exercise of 
the Covance Rights are subject to adjustment from time to time to prevent 

                                     160 
<PAGE> 

dilution (i) in the event of a stock dividend on, or a subdivision, 
combination or reclassification of, the shares of Covance Series A Preferred 
Stock, (ii) upon the grant to holders of the shares of Covance Series A 
Preferred Stock of certain rights or warrants to subscribe for or purchase 
shares of Covance Series A Preferred Stock at a price, or securities 
convertible into shares of Covance Series A Preferred Stock with a conversion 
price, less than the then current market price of the shares of Covance 
Series A Preferred Stock or (iii) upon the distribution to holders of the 
shares of Covance Series A Preferred Stock of evidences of indebtedness or 
assets (excluding regular periodic cash dividends paid out of earnings or 
retained earnings or dividends payable in shares of Covance Series A 
Preferred Stock) or of subscription rights or warrants (other than those 
referred to above). 

   The number of outstanding Covance Rights and the number of one 
one-hundredths of a share of Covance Series A Preferred Stock issuable upon 
exercise of each Covance Right are also subject to adjustment in the event of 
a stock split of, or stock dividend on, or subdivision, consolidation or 
combination of, the shares of Covance Common Stock prior to the Covance 
Rights Distribution Date. With certain exceptions, no adjustment in the 
exercise price will be required until cumulative adjustments require an 
adjustment of at least 1% in such exercise price. 

   Upon exercise of the Covance Rights, no fractional shares of Covance 
Series A Preferred Stock will be issued (other than fractions which are 
integral multiples of one one-hundredth of a share, which may, at the 
election of Covance, be evidenced by depository receipts) and in lieu thereof 
an adjustment in cash will be made. 

   The Covance Rights have certain antitakeover effects. The Covance Rights 
may cause substantial dilution for a person or group that attempts to acquire 
Covance on terms not approved by the Covance Board, except pursuant to an 
offer conditioned on a substantial number of Covance Rights being acquired. 
The Covance Rights should not interfere with any merger or other business 
combination approved by the Covance Board since the Covance Rights may be 
redeemed by Covance at $.01 per Covance Right prior to the acquisition by a 
person or group of beneficial ownership of 20% or more of the shares of 
Covance Common Stock. 

   The shares of Covance Series A Preferred Stock purchasable upon exercise 
of the Covance Rights will rank junior to all other series of Covance's 
preferred stock or any similar stock that specifically provides that they 
shall rank prior to the shares of Covance Series A Preferred Stock. The 
shares of Covance Series A Preferred Stock will be nonredeemable. Each share 
of Covance Series A Preferred Stock will be entitled to a minimum 
preferential quarterly dividend of $1 per share, but will be entitled to an 
aggregate dividend of 100 times the dividend declared per share of Covance 
Common Stock. In the event of liquidation, the holders of the shares of 
Covance Series A Preferred Stock will be entitled to a minimum preferential 
liquidation payment of $1 per share, but will be entitled to an aggregate 
payment of 100 times the payment made per share on shares of Covance Common 
Stock. Each share of Covance Series A Preferred Stock will have 100 votes, 
voting together with the shares of Covance Common Stock. In the event of any 
merger, consolidation or other transaction in which shares of Covance Common 
Stock are exchanged, each share of Covance Series A Preferred Stock will be 
entitled to receive 100 times the amount and type of consideration received 
per share of Covance Common Stock. These rights are protected by customary 
antidilution provisions. Because of the nature of the Covance Series A 
Preferred Stock's dividend, liquidation and voting rights, the value of the 
interest in a share of Covance Series A Preferred Stock purchasable upon the 
exercise of each Covance Right approximates the value of one share of Covance 
Common Stock. 
   
   The foregoing description of the Covance Rights does not purport to be 
complete and is qualified in its entirety by reference to the description of 
the Covance Rights contained in the Covance Rights Agreement, dated as of 
December 31, 1996 between Covance and the Covance Rights Agent, which 
agreement has been filed as an exhibit to Covance's registration statement on 
Form 10 (the "Covance Form 10") that Covance has filed with the Commission. 
Prior to the Covance Rights Distribution Date, the Covance Rights Agreement 
may be amended in any respect. After the Covance Rights Distribution Date, 
the Covance Rights Agreement may be amended in any respect that does not 
adversely affect the Covance Rights holders. 
    
Restrictions on Transfer 
   
  Shares of the Covance Common Stock distributed to Quest Diagnostics 
stockholders will be freely transferable, except for shares received by any 
persons who may be deemed to be "affiliates" of Covance as that term is 
defined in Rule 144 promulgated under the Securities Act, which shares will 
remain subject to the resale limitations of Rule 144. Persons who may be 
deemed to be affiliates of Covance after the Covance Spin-off Distribution 
generally include individuals or entities that control, are controlled by, or 
are under common control with Covance and may include certain officers and 
directors of Covance as well as principal stockholders of Covance. Persons 
who are affiliates of Covance 
    
                                     161 
<PAGE> 

will be permitted to sell their shares of Covance only pursuant to an 
effective registration statement under the Securities Act or an exemption 
from the registration requirements of the Securities Act, such as the 
exemption provided by Section 4(1) of the Securities Act or Rule 144 
thereunder. The Section 4(1) exemption allows the sale of unregistered shares 
by a person who is not an issuer, an underwriter or a dealer. Rule 144 
provides persons who are not issuers with objective standards for selling 
restricted securities and securities held by affiliates without registration. 
The rule requires (1) current public information be available concerning the 
issuer; (2) volume limitations be placed on sales during any three-month 
period; and (3) compliance with certain manner of sale restrictions. The 
amount of Covance Common Stock which could be sold under Rule 144 during a 
three-month period cannot exceed the greater of (1) 1% of the outstanding 
shares of Covance Common Stock, or (2) the average weekly trading volume for 
the shares for a four-week period prior to the date that notice of the sale 
is filed with the Commission. 

          ANTITAKEOVER EFFECTS OF CERTAIN PROVISIONS OF THE COVANCE 
                   CERTIFICATE OF INCORPORATION AND BY-LAWS 

General 
   
  In addition to the Covance Rights, the Covance Certificate and the Covance 
By-Laws contain other provisions that may discourage a third-party from 
seeking to acquire Covance, or to commence a proxy contest or other 
takeover-related action. These provisions, which are in all material respects 
identical to the provisions contained in the certificate of incorporation and 
By-Laws of Corning, are intended to enhance the likelihood of continuity and 
stability in the composition of the Covance Board and in the policies 
formulated by the Covance Board and to discourage certain types of 
transactions that may involve an actual or threatened change of control of 
Covance. These provisions are designed to reduce the vulnerability of Covance 
to an unsolicited acquisition proposal and also to discourage certain tactics 
that may be used in proxy fights. Because such provisions could have the 
effect of discouraging potential acquisition proposals, they may consequently 
inhibit fluctuations in the market price of Covance Common Stock which could 
result from actual or rumored takeover attempts. Such provisions also may 
have the effect of preventing changes in the management of Covance. See "Risk 
Factors--Risks Relating to Covance--Certain Antitakeover Effects." 
    
Board of Directors
 
  The Covance Certificate provides that, effective as of the Covance Spin-Off 
Distribution, the Covance Board is divided into three classes, with the 
classes to be nearly as equal as possible. One class has a term expiring at 
the 1998 annual meeting of stockholders of Covance; the second class has a 
term expiring at the 1999 annual meeting of stockholders of Covance; and the 
third class has a term expiring at the 2000 annual meeting of stockholders of 
Covance. At each annual meeting of stockholders, one class of the Covance 
Board will be elected for a three-year term. The classification of directors 
has the effect of making it more difficult to change the composition of the 
Covance Board. At least two annual meetings of stockholders, instead of one, 
generally will be required to effect a change in the majority of the Covance 
Board. The Covance Board believes that the longer time required to elect a 
majority of a classified board will help ensure the continuity and stability 
of Covance's management and policies, because in most cases a majority of the 
directors at any given time will have had prior experience as directors of 
Covance. 

   Under the DGCL, unless the certificate of incorporation otherwise 
provides, a director on a classified board may only be removed by the 
stockholders for cause. The Covance Certificate provides that a director of 
Covance is only removable by the stockholders for cause. The Covance 
Certificate limits the number of directors to twelve and requires that any 
vacancies on the Covance Board be filled only by a majority of the entire 
Covance Board. The provisions of the DGCL and the Covance Certificate 
relating to the removal of directors and the filling of vacancies on the 
Covance Board preclude a third-party from removing incumbent directors 
without cause and simultaneously gaining control of the Covance Board by 
filling, with its own nominees, the vacancies created by removal. These 
provisions also reduce the power of stockholders generally, even those with a 
majority voting power in Covance, to remove incumbent directors and to fill 
vacancies on the Covance Board without the support of the incumbent 
directors. 

Stockholder Action and Special Meetings 

  The Covance Certificate provides that all stockholder actions to be effected 
by written consent and not a duly called meeting must be effected by the 
unanimous written consent of all stockholders entitled to consent thereto. 

                                     162 
<PAGE> 

This provision reduces the power of the Covance stockholders and precludes a 
stockholder of Covance from conducting any form of consent solicitation. The 
Covance Certificate also does not permit stockholders of Covance to call 
special meetings of stockholders. 

Advance Notice Requirements for Stockholder Proposals and Director 
Nominations 

  The Covance By-Laws contain an advance notice procedure with respect to the 
nomination, other than by or at the direction of the Covance Board or a 
committee thereof, of candidates for election as directors as well as for 
other stockholder proposals to be considered at annual meetings of 
stockholders. Delivery of a notice with the required information must be 
delivered to the Secretary of Covance not later than 60 days nor more than 90 
days prior to the date of the stockholders' meeting at which the nomination 
or other proposal is to be considered. No matters can be considered at 
special meetings of the stockholders other than such matters as are set forth 
in the notice of meeting. Although the notice provisions do not give the 
Covance Board any power to approve or disapprove stockholder nominations or 
proposals for action by Covance, they may have the effect of (i) precluding a 
contest for the election of directors or the consideration of stockholder 
proposals if the procedures established by the Covance By-Laws are not 
followed and (ii) discouraging or deterring any third-party from conducting a 
solicitation of proxies to elect its own slate of directors or to approve its 
proposals, without regard to whether consideration of such nominees or 
proposals might be harmful or beneficial to Covance and its stockholders. The 
purpose of requiring advance notice is to afford the Covance Board an 
opportunity to consider the qualifications of the proposed nominees or the 
merits of other stockholder proposals and, to the extent deemed necessary or 
desirable by the Covance Board, to inform stockholders about those matters. 

Business Combinations with Interested Stockholders 

  Paragraph 6 of the Covance Certificate (the "Fair Price Amendment") requires 
the approval by the holders of at least 80% of the voting power of the 
outstanding capital stock of Covance entitled to vote generally in the 
election of directors (the "Covance Voting Stock") as a condition for mergers 
and certain other Business Combinations (as defined below) with any 
beneficial owner of more than 10% of such voting power (an "Interested 
Stockholder") unless (i) the transaction is approved by at least a majority 
of the Continuing Directors (as defined below) or (ii) certain minimum price, 
form of consideration and procedural requirements are met. 

   An Interested Stockholder, in general, is defined as any person or group 
who is, or was at any time within the two-year period immediately prior to 
the date in question, the beneficial owner of more than 10% of the voting 
power of the Covance Voting Stock. The term "beneficial owner" includes 
persons directly or indirectly owning or having the right to acquire or vote 
the shares. In certain circumstances, an Interested Stockholder could include 
persons or entities affiliated or associated with the Interested Stockholder. 

   A Business Combination generally includes the following transactions: (i) 
a merger or consolidation of Covance or any subsidiary with an Interested 
Stockholder; (ii) the sale or other disposition by Covance or a subsidiary of 
assets having an aggregate fair market value of $20,000,000 or more if an 
Interested Stockholder is a party to the transaction; (iii) the issuance or 
transfer of stock or other securities of Covance or of a subsidiary to an 
Interested Stockholder in exchange for cash or property (including stock or 
other securities) having an aggregate fair market value of $20,000,000 or 
more; (iv) the adoption of any plan or proposal for the liquidation or 
dissolution of Covance proposed by or on behalf of an Interested Stockholder; 
(v) any reclassification of securities, recapitalization, merger or 
consolidation with a subsidiary or other transaction which has the effect, 
directly or indirectly, of increasing the percentage of the outstanding stock 
of any class of Covance or a subsidiary owned by an Interested Stockholder; 
or (vi) any agreement, contract or other arrangement providing for any one or 
more of the foregoing actions. 

   A Continuing Director is in general (i) any member of the Covance Board 
who is not an Interested Stockholder or affiliated or associated with an 
Interested Stockholder and was a director of Covance prior to the time the 
Interested Stockholder became an Interested Stockholder and any successor to 
such a Continuing Director who is not affiliated or associated with an 
Interested Stockholder and was recommended or elected by a majority of the 
Continuing Directors then on the Covance Board, or (ii) any person who was a 
director of Covance as of the Distribution Date and any successor thereto who 
was recommended or elected by a majority of the Continuing Directors then on 
the Covance Board. It is possible that the approval of a majority of the 
Continuing Directors could be obtained in circumstances where the Continuing 
Directors constitute less than a quorum of the entire Covance Board. 

                                     163 
<PAGE> 

   The 80% affirmative stockholder vote would not be required if the Business 
Combination in question had been approved by a majority of the Continuing 
Directors or if all the minimum price, form of consideration and procedural 
requirements described below are satisfied. 

   Minimum Price and Form of Consideration Requirements. In a Business 
Combination involving cash or other consideration being paid to Covance's 
stockholders, the consideration required, in the case of each class of 
Covance Voting Stock, would be either cash or the same type of consideration 
used by the Interested Stockholder in acquiring the largest portion of its 
shares of that class of Covance Voting Stock prior to the first public 
announcement of the proposed Business Combination. In addition, such 
consideration would be required to meet the minimum price requirements 
described below. 

   In the case of payments to holders of Covance Common Stock, the fair 
market value per share of such payments would be at least equal in value to 
the higher of (i) the highest per share price paid by the Interested 
Stockholder in acquiring any shares of Covance Common Stock during the two 
years prior to the first public announcement of the proposed Business 
Combination (the "Announcement Date") or in the transaction in which it 
became an Interested Stockholder, whichever is higher, and (ii) the fair 
market value per share of Covance Common Stock on the Announcement Date or on 
the date on which the Interested Stockholder became an Interested 
Stockholder, whichever is higher. 

   In the case of payments to holders of any series of voting Covance Series 
Preferred Stock, if any, the fair market value per share of such payments 
would have to be at least equal to the higher of (i) the price per share 
determined with respect to shares of such series in the same manner as 
described in the preceding paragraph with respect to shares of Covance Common 
Stock and (ii) the highest preferential amount per share to which the holders 
of such series of Covance Series Preferred Stock are entitled in the event of 
a voluntary or involuntary liquidation of Covance. 

   If the transaction does not involve any cash or other property being 
received by any of the other stockholders, such as a sale of assets or an 
issuance of Covance's securities to an Interested Stockholder, then the 
minimum price, form of consideration and procedural requirements would not 
apply, but an 80% vote of stockholders would still be required unless the 
transaction was approved by a majority of the Continuing Directors. 

   Procedural Requirements. An 80% stockholder vote would be required to 
authorize a Business Combination with an Interested Stockholder if Covance, 
after the Interested Stockholder became an Interested Stockholder, had failed 
to pay full quarterly dividends on its Preferred Stock, if any, or reduced 
the rate of dividends paid on its Common Stock, unless such failure or 
reduction was approved by a majority of the Continuing Directors. 

   An 80% stockholder vote to authorize a Business Combination with an 
Interested Stockholder would also be required if the Interested Stockholder 
had acquired any additional shares of the Covance Voting Stock, directly from 
Covance or otherwise, in any transaction subsequent to the transaction 
pursuant to which it became an Interested Stockholder. 

   The receipt by the Interested Stockholder at any time after it became an 
Interested Stockholder, whether in connection with the proposed Business 
Combination or otherwise, of the benefit of any loans or other financial 
assistance or tax advantages provided by Covance (other than proportionately 
as a stockholder) would also trigger the 80% stockholder vote requirement to 
authorize a Business Combination with an Interested Stockholder (unless the 
Business Combination was approved by a majority of the Continuing Directors). 

   In summary, none of the minimum price, form of consideration or procedural 
requirements described above would apply in the case of a Business 
Combination approved by a majority of the Continuing Directors. In the 
absence of such approval, all of such requirements would have to be satisfied 
to avoid the 80% stockholder vote requirements. 

Amendment of the Covance Certificate 

  Amendment or repeal of the provisions of the Covance Certificate described 
above or the adoption of any provision inconsistent therewith would require 
the affirmative vote of at least 80% of the Covance Voting Stock unless the 
proposed amendment or repeal or the adoption of the inconsistent provisions 
are approved by two-thirds of the entire Covance Board and a majority of the 
Continuing Directors. 

                                     164 
<PAGE> 

Antitakeover Statutes 

  Section 203 of the DGCL prohibits transactions between a Delaware 
corporation and an "interested stockholder," which is defined therein as a 
person who, together with any affiliates and/or associates of such person, 
beneficially owns, directly or indirectly, 15% or more of the outstanding 
voting shares of a Delaware corporation. This provision prohibits certain 
business combinations (defined broadly to include mergers, consolidations, 
sales or other dispositions of assets having an aggregate value in excess of 
10% of the consolidated assets of the corporation, and certain transactions 
that would increase the interested stockholder's proportionate share 
ownership in the corporation) between an interested stockholder and a 
corporation for a period of three years after the date the interested 
stockholder acquired its stock unless (i) the business combination is 
approved by the corporation's board of directors prior to the date the 
interested stockholder acquired shares, (ii) the interested stockholder 
acquired at least 85% of the voting stock of the corporation in the 
transaction in which it becomes an interested stockholder, or (iii) the 
business combination is approved by a majority of the board of directors and 
by the affirmative vote of 662/3% of the votes entitled to be cast by 
disinterested stockholders at an annual or special meeting. The Covance 
Certificate and the Covance By-Laws do not exclude Covance from the 
restrictions imposed under Section 203 of the DGCL. 

Tax Sharing and Indemnification Agreements 

   
  The corporate tax liability which potentially could arise from an 
acquisition of shares of Covance capital stock or assets of Covance for a 
period of time following the Covance Spin-Off Distribution, together with the 
related indemnification arrangements contained in the Tax Sharing and 
Spin-Off Tax Indemnification Agreements, could have an antitakeover effect on 
the acquisition of control of Covance. See "The Relationship Among Corning, 
Quest Diagnostics and Covance After the Distributions--Tax Sharing Agreement" 
and "The Relationship Among Corning, Quest Diagnostics and Covance After the 
Distributions--Spin-Off Tax Indemnification Agreements." 
    

                                     165 
<PAGE> 
   
                DESCRIPTION OF CERTAIN INDEBTEDNESS OF COVANCE 

  Covance is currently negotiating with several banks and financial 
institutions (the "Covance Lenders") for a five year $250,000,000 Senior 
Revolving Credit Facility (the "Covance Credit Facility") to be entered into 
prior to the Covance Spin-Off Distribution, with the Covance Lenders, 
NationsBank N.A. ("NationsBank"), as administrative agent, and Wachovia Bank 
of Georgia, N.A., as syndication agent (collectively, the "Agents"). A copy 
of the proposed form of the Covance Credit Facility will be filed as an 
exhibit to the Covance Form 10. This summary of the terms and conditions of 
the Covance Credit Facility does not purport to be complete and is qualified 
in its entirety by reference to such proposed form, including the definitions 
contained therein. 

  The Covance Credit Facility will be guaranteed by certain material U.S. 
subsidiaries (i.e., U.S. subsidiaries whose assets represent individually at 
least 5% of the total assets of Covance and its subsidiaries) and, in certain 
circumstances, other subsidiaries. Additionally, the Covance Credit Facility 
will be secured by 65% of the voting stock of each of the material (and, in 
certain circumstances, other) first-tier foreign subsidiaries, and by 
intercompany notes evidencing loans made by U.S. material subsidiaries to 
U.S. non-material subsidiaries of Covance. The proceeds of the Covance Credit 
Facility will be used to effect the Covance Spin-Off Distribution (including 
(i) the refinancing of certain intercompany indebtedness and taxes owed to 
Corning of approximately $150 million to $160 million and (ii) the payment of 
approximately $5.0 million in transaction costs), and to provide financing 
for Covance's and its subsidiaries' working capital needs (including the 
issuance by NationsBank letters of credit not to exceed $25 million), capital 
expenditures, acquisitions and other lawful corporate purposes. 

  Covance may borrow U.S. Dollars, British Pounds Sterling, German 
Deutschmarks, Swiss Francs or Japanese Yen under the Covance Credit Facility 
until the fifth anniversary thereof, at which time all outstanding loans and 
other amounts must be paid in full. Covance may prepay the loans under the 
Covance Credit Facility in whole or in part (subject to reimbursement of 
breakage costs associated with loans based on the Eurocurrency Rate, as 
defined below) and may permanently reduce or terminate the Covance Lenders' 
commitments. 

Interest 

         Under the Covance Credit Facility, Covance may choose to obtain
"Revolving Loans," "Competitive Bid Loans" or "Swing Line Loans." A Revolving
Loan bears interest, at Covance's option, at either (i) the "Base Rate" (defined
as the higher of (a) the NationsBank prime rate and (b) the federal funds rate
plus .50%), payable quarterly, or (ii) the "Eurocurrency Rate" plus the
"Applicable Percentage", payable at the end of each one, two, three or six month
interest period selected by Covance (and also quarterly, in the case of a six
month interest period). The Eurocurrency Rate is the average rate per annum
appearing on Telerate Page 3750 (or any successor page, or if not published on
Telerate Page 3750 then the rate or the arithmetic mean of any rates per annum
specified on Reuters Screen LIBO page) for deposits in U.S. Dollars or any other
applicable currency two business days prior to the first day of any applicable
interest period for a term comparable to such interest period, as adjusted for
reserve requirements. The Applicable Percentage is a percentage per annum, which
will be .25% until the fifth business day following March 31, 1997 and
thereafter will be determined quarterly (and depending on such determination,
may vary between .17% and .45%) based, at Covance's option, upon either (i) the
lowest debt rating as of each quarterly calculation date announced by Standard &
Poor's Ratings Group or Moody's Investors Service, Inc., as the case may be, for
any class of long-term senior unsecured debt issued by the Covance or (ii)
Covance's Leverage Ratio as defined below (as adjusted). A Competitive Bid Loan
bears interest, at Covance's option, at either (i) a fixed rate offered by a
Covance Lender and accepted by Covance, payable at the end of the interest
period selected by Covance, which interest period may not exceed 180 days (and
also quarterly, in the case of a period longer than three months), or (ii) the
Eurocurrency Rate plus the margin offered by such Covance Lender and accepted by
Covance, payable at the end of each one, two, three or six month interest period
selected by Covance (and also, quarterly in the case of a six month interest
period). Swing Line Loans (made by NationsBank and limited to $10,000,000) may
at Covance's option, bear interest at either (i) the Base Rate, payable
quarterly or (ii) a rate quoted by NationsBank as the "Quoted Rate", payable at
the end of the interest period selected by Covance (and also quarterly, in the
case of an interest period greater than three months).

Fees 

  Covance will pay quarterly as a percentage of the aggregate amount of 
letters of credit issued and outstanding (a) an issuing lender fee of 1/8% 
and (b) a letter of credit fee of .25% until the fifth business day following 
March 
    
                                     166 
<PAGE> 
   
31, 1997 and thereafter at a rate equal to the Applicable Percentage, ranging 
between .17% and .45%. Covance will also pay quarterly, based on the 
aggregate amount of commitments under the Covance Credit Facility, a facility 
fee of .125% until the fifth business day following March 31, 1997 and 
thereafter at a rate equal to the Applicable Percentage, ranging between .08% 
and .20%. 

Covenants 

     The Covance Credit Facility will contain covenants which place
restrictions on Covance and/or the guarantors (subject to certain exceptions),
including with respect to (i) the incurrence of additional indebtedness, (ii)
the incurrence of additional liens, (iii) material changes in the nature of the
business of Covance or the guarantors, (iv) mergers and consolidations, (v)
entry into certain sale/leaseback transactions, (vi) investments and (vii) the
payment of dividends.

   Covance will be required to maintain, for each fiscal quarter, (i) a 
minimum ratio for the 12 month period ending with such fiscal quarter (the 
"Fixed Charge Coverage Ratio") of (A) EBIT plus all rent expense payable 
under operating leases to (B) Interest Expense plus such rent expense, of 2.0 
to 1.0 until December 31, 1997, and 2.25 to 1.0 thereafter and (ii) a maximum 
ratio (the "Leverage Ratio") of Funded Debt, as of the end of such fiscal 
quarter, to EBITDA for the 12 month period ending with such fiscal quarter, 
of 3.30 to 1.0 until March 31, 1997, 3.25 to 1.0 until September 30, 1997, 
3.0 to 1.0 until March 31, 1998 and 2.75 to 1.0 thereafter. EBIT is the sum 
of consolidated net income (net of extraordinary gains and losses, including 
the one-time restructuring charge associated with the Covance Spin-Off 
Distribution), and income tax expense and interest expense. Funded Debt means 
(i) indebtedness with respect to borrowed money, (ii) purchase money 
indebtedness, (iii) capital lease obligations, (iv) letter of credit 
obligations and (v) guarantees. EBITDA is EBIT plus depreciation and 
amortization expense. 
    
                                     167 
<PAGE> 


                       LIABILITY AND INDEMNIFICATION OF 
                      DIRECTORS AND OFFICERS OF COVANCE 

Limitation on Liability of Directors 
  Pursuant to authority conferred by Section 102 of the DGCL, Paragraph 11 of 
the Covance Certificate ("Paragraph 11") eliminates the personal liability of 
Covance's directors to Covance or its stockholders for monetary damages for 
breach of fiduciary duty, including without limitation, directors serving on 
committees of the Covance Board. Directors remain liable for (1) any breach 
of the duty of loyalty to Covance or its stockholders, (2) any act or 
omission not in good faith or which involves intentional misconduct or a 
knowing violation of law, (3) any violation of Section 174 of the DGCL, which 
proscribes the payment of dividends and stock purchases or redemptions under 
certain circumstances, and (4) any transaction from which directors derive an 
improper personal benefit. 

Indemnification and Insurance 
  In accordance with Section 145 of the DGCL, which provides for the 
indemnification of directors, officers and employees under certain 
circumstances, Paragraph 11 grants Covance's directors and officers a right 
to indemnification for all expenses, liabilities and losses relating to 
civil, criminal, administrative or investigative proceedings to which they 
are a party (1) by reason of the fact that they are or were directors and 
officers of Covance or (2) by reason of the fact that, while they are or were 
directors or officers of Covance, they are or were serving at the request of 
Covance as directors or officers of another corporation, partnership, joint 
venture, trust or enterprise. Paragraph 11 further provides for the mandatory 
advancement of expenses incurred by officers and directors in defending such 
proceedings in advance of their final disposition upon delivery to Covance by 
the indemnitee of an undertaking to repay all amounts so advanced if it is 
ultimately determined that such indemnitee is not entitled to be indemnified 
under Paragraph 11. Covance may not indemnify or make advance payments to any 
person in connection with proceedings initiated against Covance by such 
person without the authorization of the Covance Board. 

   In addition, Paragraph 11 provides that directors and officers therein 
described shall be indemnified to the fullest extent permitted by Section 145 
of DGCL, or any successor provisions or amendments thereunder. In the event 
that any such successor provisions or amendments provide indemnification 
rights broader than permitted prior thereto, Paragraph 11 allows such broader 
indemnification rights to apply retroactively with respect to any predating 
alleged action or inaction and also allows the indemnification to continue 
after an indemnitee has ceased to be a director or officer of Covance and to 
inure to the benefit of the indemnitee's heirs, executors and administrators. 

   Paragraph 11 further provides that the right to indemnification is not 
exclusive of any other right which any indemnitee may have or thereafter 
acquire under any statute, the Covance By-Laws, any agreement or vote of 
stockholders or disinterested directors or otherwise, and allows Covance to 
indemnify and advance expenses to any person whom the corporation has the 
power to indemnify under the DGCL or otherwise. 

   Insofar as indemnification for liabilities arising under the Securities 
Act may be permitted for directors and officers and controlling persons 
pursuant to the foregoing provisions, Covance has been advised that in the 
opinion of the Commission such indemnification is against public policy as 
expressed in the Securities Act and is, therefore, unenforceable. 

   The Covance Certificate authorizes Covance to purchase insurance for 
directors, officer, employees and agents of Covance and persons who serve at 
the request of Covance as directors, officers, employees or agents of another 
corporation against any expense, liability or loss incurred in such capacity, 
whether or not Covance would have the power to indemnify such persons against 
such expense or liability under the DGCL. Covance intends to maintain 
insurance coverage of its officers and directors as well as insurance 
coverage to reimburse Covance for potential costs of its corporate 
indemnification of directors and officers. 

                                       168

<PAGE>



                         INDEX TO FINANCIAL STATEMENTS

<TABLE>
<CAPTION>
                                                                                                       Page 
                                                                                                    --------- 
<S>                                                                                                 <C>
   
FINANCIAL STATEMENTS OF COVANCE INC. 
Report of Price Waterhouse LLP--Independent Accountants                                                F-29 
Combined Financial Statements: 
 Combined Balance Sheets--December 31, 1995 and 1994                                                   F-30 
 Combined Statements of Income--Years ended December 31, 1995, 1994 and 1993                           F-31 
 Combined Statements of Cash Flows--Years ended December 31, 1995, 1994 and 1993                       F-32 
 Combined Statements of Stockholder's Equity--Years ended December 31, 1995, 1994 and 1993             F-33 
 Notes to Combined Financial Statements                                                                F-34 
 Quarterly Operating Results (unaudited)                                                               F-40 
Interim Combined Financial Statements (unaudited): 
 Combined Balance Sheets--September 30, 1996 and December 31, 1995                                     F-41 
 Combined Statements of Income--Three and Nine Months ended September 30, 1996 and 1995                F-42 
 Combined Statements of Cash Flows--Nine Months ended September 30, 1996 and 1995                      F-43 
 Notes to Combined Interim Financial Statements                                                        F-44 
</TABLE>
    

                                     F-1 

<PAGE>

                      REPORT OF INDEPENDENT ACCOUNTANTS 

   To the Boards of Directors and Stockholders of Corning Incorporated and 
   Covance Inc. 

   In our opinion, the accompanying combined balance sheets and the related 
combined statements of income, of cash flows and of stockholder's equity 
appearing on pages F-30 through F-40 present fairly, in all material 
respects, the financial position of Covance Inc. and its subsidiaries (an 
indirect wholly-owned business of Corning Incorporated) at December 31, 1995 
and 1994, and the results of their operations and their cash flows for each 
of the three years in the period ended December 31, 1995, in conformity with 
generally accepted accounting principles. These financial statements are the 
responsibility of the Company's management; our responsibility is to express 
an opinion on these financial statements based on our audits. We conducted 
our audits of these statements in accordance with generally accepted auditing 
standards which require that we plan and perform the audit to obtain 
reasonable assurance about whether the financial statements are free of 
material misstatement. An audit includes examining, on a test basis, evidence 
supporting the amounts and disclosures in the financial statements, assessing 
the accounting principles used and significant estimates made by management 
and evaluating the overall financial statement presentation. We believe that 
our audits provide a reasonable basis for the opinion expressed above. 


/s/ Price Waterhouse LLP 

Price Waterhouse LLP 
New York, NY 
July 29, 1996 

The accompanying notes are an integral part of these statements. 

                                     F-29 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
                           COMBINED BALANCE SHEETS 
                          DECEMBER 31, 1995 AND 1994 


(Amounts in thousands)                               1995        1994 
                                                  ----------- ----------- 
Assets 
Current Assets: 
  Cash and cash equivalents                        $  8,068    $  6,176 
  Accounts receivable, net                           78,968      66,781 
  Unbilled services                                  18,217      13,194 
  Inventory                                          14,004      10,729 
  Deferred income taxes                              11,337      10,033 
  Prepaid expenses and other assets                  15,189      11,849 
                                                   --------    -------- 
   Total Current Assets                             145,783     118,762 
  Property and equipment, net                       140,708     126,483 
  Goodwill, net                                      24,028      15,880 
  Other assets                                       11,991      10,867 
                                                   --------    -------- 
   Total Assets                                    $322,510    $271,992 
                                                   ========    ======== 
Liabilities and Stockholder's Equity 
Current Liabilities: 
  Trade accounts payable                           $ 23,761    $ 16,690 
  Accrued payroll and benefits                       20,339      15,775 
  Accrued expenses and other liabilities             24,701      16,243 
  Unearned revenue                                   41,879      49,135 
  Income taxes payable                               16,631       7,958 
                                                   --------    -------- 
   Total Current Liabilities                        127,311     105,801 
  Due to Corning Incorporated and affiliates         89,836      75,178 
  Deferred income taxes                               6,406       9,605 
  Other liabilities                                  16,440      17,500 
                                                   --------    -------- 
   Total Liabilities                                239,993     208,084 
                                                   --------    -------- 
Commitments and Contingent Liabilities 
Stockholder's Equity: 
  Contributed capital                                30,816      26,528 
  Retained earnings                                  48,653      34,656 
  Cumulative translation adjustment                   3,048       2,724 
                                                   --------    -------- 
    Total Stockholder's Equity                       82,517      63,908 
                                                   --------    -------- 
    Total Liabilities and Stockholder's Equity     $322,510    $271,992 
                                                   ========    ======== 


  The accompanying notes are an integral part of these financial statements. 

                                     F-30 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
                        COMBINED STATEMENTS OF INCOME 
             FOR THE YEARS ENDED DECEMBER 31, 1995, 1994 AND 1993 


<TABLE>
<CAPTION>
(Amounts in thousands)                                1995        1994        1993 
                                                    --------    --------    -------- 
<S>                                                 <C>         <C>         <C>      
Net revenues                                        $409,174    $319,501    $289,697 
Cost and expenses 
 Cost of revenue                                     270,726     213,490     192,783 
 Selling, general and administrative expenses         64,201      48,892      42,949 
 Restructuring charge                                  4,616          --          -- 
 Depreciation and amortization                        22,070      18,520      16,984 
                                                    --------    --------    -------- 
   Total                                             361,613     280,902     252,716 
                                                    --------    --------    -------- 
Income from operations                                47,561      38,599      36,981 
                                                    --------    --------    -------- 
Other expense (income) 
 Interest expense, net                                 5,269       4,307       4,421 
 Foreign exchange (gain) loss                           (784)       (712)        852 
                                                    --------    --------    -------- 
                                                       4,485       3,595       5,273 
                                                    --------    --------    -------- 
Income before taxes and equity investee loss          43,076      35,004      31,708 
Taxes on income                                       18,445      14,924      13,506 
Equity investee loss                                     405         435       1,391 
                                                    --------    --------    -------- 
Net income                                          $ 24,226    $ 19,645    $ 16,811 
                                                    ========    ========    ======== 
</TABLE>

  The accompanying notes are an integral part of these financial statements. 


                                     F-31 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
                      COMBINED STATEMENTS OF CASH FLOWS 
             FOR THE YEARS ENDED DECEMBER 31, 1995, 1994 AND 1993 


<TABLE>
<CAPTION>
(Amounts in thousands)                               1995        1994        1993 
                                                   --------    --------    -------- 
<S>                                                <C>         <C>         <C>      
Cash flows from operating activities 
Net income                                         $ 24,226    $ 19,645    $ 16,811 
Adjustments to reconcile net income to net cash 
  provided by operating activities: 
  Depreciation and amortization                      22,070      18,520      16,984 
  Restructuring reserve, net of cash paid             2,965          --          -- 
  Deferred income tax provision                      (4,503)     (1,502)     (2,879) 
  Related party charges                               3,288       3,504       4,443 
  Other                                               1,266       1,375       2,276 
Changes in operating assets and liabilities 
  Accounts receivable                               (10,082)    (11,706)     (8,814) 
  Unbilled services                                  (5,023)      2,058      (1,973) 
  Inventory                                          (2,576)       (603)        378 
  Accounts payable                                    6,783       4,372        (898) 
  Accrued liabilities                                11,669       7,550       3,058 
  Unearned revenue                                   (7,556)      2,894       1,607 
  Income taxes payable                                8,673         194       4,351 
  Other assets and liabilities, net                  (6,094)     (3,369)      5,156 
                                                   --------    --------    -------- 
NET CASH PROVIDED BY OPERATING ACTIVITIES            45,106      42,932      40,500 
                                                   --------    --------    -------- 
CASH FLOWS FROM INVESTING ACTIVITIES 
  Capital expenditures                              (34,792)    (25,242)    (24,893) 
  Acquisition of businesses                         (14,000)    (10,789)         -- 
  Other, net                                            571      (2,432)        351 
                                                   --------    --------    -------- 
NET CASH USED IN INVESTING ACTIVITIES               (48,221)    (38,463)    (24,542) 
                                                   --------    --------    -------- 
CASH FLOWS FROM FINANCING ACTIVITIES 
  Due to Corning Incorporated and affiliates            236      (4,710)     (8,677) 
  Acquisition loan from Corning Incorporated         14,000      10,789          -- 
  Capital contributions                               1,000          --          -- 
  Dividends paid                                    (10,229)     (9,465)     (8,681) 
                                                   --------    --------    -------- 
NET CASH PROVIDED BY (USED IN) FINANCING 
 ACTIVITIES                                           5,007      (3,386)    (17,358) 
                                                   --------    --------    -------- 
NET CHANGE IN CASH AND CASH EQUIVALENTS               1,892       1,083      (1,400) 
CASH AND CASH EQUIVALENTS, BEGINNING OF YEAR          6,176       5,093       6,493 
                                                   --------    --------    -------- 
CASH AND CASH EQUIVALENTS, END OF YEAR             $  8,068    $  6,176    $  5,093 
                                                   ========    ========    ======== 
</TABLE>

  The accompanying notes are an integral part of these financial statements. 

                                     F-32 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
                 COMBINED STATEMENTS OF STOCKHOLDER'S EQUITY 
             FOR THE YEARS ENDED DECEMBER 31, 1995, 1994 AND 1993 


<TABLE>
<CAPTION>
                                                                 Cumulative         Total 
                                     Contributed    Retained    Translation     Stockholder's 
(Amounts in thousands)                 Capital      Earnings     Adjustment        Equity 
                                       -------      --------       ------         -------- 
<S>                                    <C>          <C>            <C>            <C>      
Balance, December 31, 1992             $18,581      $ 16,346       $2,270         $ 37,197 
Net income                                  --        16,811           --           16,811 
Dividends paid                              --        (8,681)          --           (8,681) 
Capital contribution                     4,443            --           --            4,443 
Currency translation adjustment             --            --         (382)            (382) 
                                       -------      --------       ------         -------- 
Balance, December 31, 1993              23,024        24,476        1,888           49,388 
Net income                                  --        19,645           --           19,645 
Dividends paid                              --        (9,465)          --           (9,465) 
Capital contribution                     3,504            --           --            3,504 
Currency translation adjustment             --            --          836              836 
                                       -------      --------       ------         -------- 
Balance, December 31, 1994              26,528        34,656        2,724           63,908 
Net income                                  --        24,226           --           24,226 
Dividends paid                              --       (10,229)          --          (10,229) 
Capital contribution                     4,288            --           --            4,288 
Currency translation adjustment             --            --          324              324 
                                       -------      --------       ------         -------- 
Balance, December 31, 1995             $30,816      $ 48,653       $3,048         $ 82,517 
                                       =======      ========       ======         ======== 
</TABLE>

  The accompanying notes are an integral part of these financial statements. 

                                     F-33 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
                    NOTES TO COMBINED FINANCIAL STATEMENTS 
              (Dollars in thousands, unless otherwise indicated) 

1. Organization 
   Covance Inc. (formerly Corning Pharmaceutical Services Inc.) and its 
subsidiaries ("Covance") is a leading contract research organization 
providing a wide range of integrated product development services on a 
worldwide basis to the biotechnology, pharmaceutical and medical device 
industries. In addition, and to a lesser extent, Covance provides services 
such as health economics for managed care organizations, hospitals and health 
care provider networks, and early development and laboratory testing services 
to the chemical, agrochemical and food industries. Covance's operations 
involve a single industry segment for financial reporting purposes. At the 
present time, operations are principally focused in the United States and 
Europe. 

   Covance is an indirect wholly-owned business of Corning Incorporated 
("Corning"). In May 1996, Corning's Board of Directors approved a plan to 
distribute to its stockholders on a pro rata basis all of the shares of 
Covance (the "Covance Spin-Off Distribution"). The result of the plan will be 
the creation of an independent, publicly-owned (but as yet unnamed) company. 
Corning has submitted to the Internal Revenue Service a request for a ruling 
that the Covance Spin-Off Distribution will qualify as a tax free 
distribution under the Internal Revenue Code of 1986, as amended. The final 
terms of the Covance Spin-Off Distribution, which are subject to approval by 
Corning's Board of Directors, will be set forth in a registration statement 
to be filed with the Securities and Exchange Commission and in an Information 
Statement to be distributed to Corning's stockholders. The Covance Spin-Off 
Distribution is expected to occur by the end of 1996. 

2. Summary of Significant Accounting Policies 

   
   Basis of Presentation 
   The operations of Covance Biotechnology Services Inc. (formerly Corning 
Bio Inc.), a majority-owned business of Corning which Corning intends to 
contribute to Covance prior to the Covance Spin-Off Distribution, are 
included in the accompanying financial statements. Accordingly, the 
accompanying financial statements present the results of Covance and Covance 
Biotechnology on a combined basis. 
    

   Principles of Consolidation 
   The combined financial statements include the accounts of all entities 
controlled by Covance, including Covance Biotechnology. All significant 
intercompany accounts and transactions are eliminated. The equity method of 
accounting is used for investments in affiliates in which Covance owns 
between 20 and 50 percent. 

   Use of Estimates 
   The preparation of financial statements in conformity with generally 
accepted accounting principles requires management to make estimates and 
assumptions that affect the reported amounts of assets and liabilities, 
disclosure of contingent assets and liabilities at the date of the financial 
statements and the reported amounts of revenues and expenses during the 
reporting period. Actual results could differ from these estimates. 

   Foreign Currencies 
   For subsidiaries outside of the United States that operate in a local 
currency environment, assets and liabilities are translated to United States 
dollars at year-end exchange rates. Income and expense items are translated 
at average rates of exchange prevailing during the year. Translation 
adjustments are accumulated in a separate component of stockholder's equity. 
Transaction gains and losses are included in the determination of income. 

   Cash and Cash Equivalents 
   Cash and cash equivalents include all highly liquid investments with an 
original maturity of three months or less at date of purchase and consist 
principally of amounts temporarily invested in money market funds. 

   Financial Instruments 
   The fair value of cash, accounts receivable, trade accounts payable and 
accrued expenses are not materially different than their carrying amounts as 
reported at December 31, 1995 and 1994. 

                                     F-34 
<PAGE> 


                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
              NOTES TO COMBINED FINANCIAL STATEMENTS (Continued) 
              (Dollars in thousands, unless otherwise indicated) 

   Accounts receivable and unbilled services from Covance customers are 
concentrated primarily in the pharmaceutical and biotechnology industries. 
Covance monitors the creditworthiness of its customers to which it grants 
credit terms in the ordinary course of business. Although Covance customers 
are concentrated primarily within these two industries, management considers 
the likelihood of material credit risk exposure as remote. Covance in some 
cases requires advance payment for a portion of the contract price from its 
customers upon the signing of a contract for services. Historically, bad 
debts have been minimal. 

   Inventory 
   Inventories, which consist principally of supplies, are valued at the 
lower of cost (first-in, first-out method) or market. 

   Property and Equipment 
   Property and equipment are recorded at cost. Depreciation and amortization 
are provided on the straight line method at rates adequate to allocate the 
cost of the applicable assets over their estimated useful lives, which range 
in term from three to thirty years. 

   Goodwill 
   Goodwill (investment costs in excess of the fair value of net tangible 
assets acquired) is capitalized and amortized over the period expected to be 
benefited, generally forty years. 

   Impairment of Long-Lived Assets 
   Statement of Financial Accounting Standards No. 121, "Accounting for the 
Impairment of Long-Lived Assets and for Long-Lived Assets to Be Disposed Of" 
("SFAS No. 121"), was adopted in 1995. Assessments of the recoverability of 
long-lived assets are conducted when events or changes in circumstances occur 
that indicate that the carrying value of the asset may not be recoverable. 
The assessment of possible impairment is based upon the ability to recover 
the asset from the expected future undiscounted cash flows of related 
operations. The policy on impairment prior to the adoption of SFAS No. 121 
was not materially different. 

   Revenue Recognition 
   Revenue is recognized using the cost-to-cost type of 
percentage-of-completion method of accounting for services rendered in 
connection with contractual arrangements, which generally range from a few 
months to two years. Revenue is recognized as costs are incurred on the basis 
of the relationship between costs incurred and total estimated costs. Most 
service contracts may be terminated for a variety of reasons by Covance's 
customers either immediately or upon notice. The contracts often require 
payments to Covance to recover costs incurred, including costs to wind down 
the study and fees earned to date, and in some cases to provide Covance with 
a portion of the fees or profits that would have been earned under the 
contract had the contract not been terminated early. Contracts may contain 
provisions for renegotiation in the event of cost overruns due to changes in 
the level of work scope. Renegotiated amounts are included in revenue when 
earned and realization is assured. Provisions for losses to be incurred on 
contracts are recognized in full in the period in which it is determined that 
a loss will result from performance of the contractual arrangement. 

   Revenue from performing clinical laboratory testing services is recognized 
as tests are completed. Revenue from other activities is recognized as 
services are performed or products are shipped. 

   Unbilled receivables are recorded for revenue recognized to date that is 
currently unbillable to the customer pursuant to contractual terms. In 
general, amounts become billable upon the achievement of milestones or in 
accordance with predetermined payment schedules. Unbilled receivables are 
billable to customers within one year from the respective balance sheet date. 
Unearned revenue is recorded for advance billings to customers for which 
revenue has not been recognized at a given date. 

   Covance routinely subcontracts with independent physician investigators in 
connection with multi-site clinical trials. Investigator fees are not 
reflected in revenue or expense since such fees are granted by customers on a 
"pass-thru basis" without risk or reward to Covance. 


                                     F-35 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
              NOTES TO COMBINED FINANCIAL STATEMENTS (Continued) 
              (Dollars in thousands, unless otherwise indicated) 

   Costs and Expenses 
   Cost of revenue generally includes appropriate amounts necessary to 
complete the revenue earning process which encompass direct labor and related 
benefit charges, other direct costs and allocable expenses (including 
facility charges, indirect labor and information technology costs). Selling, 
general and administrative expenses primarily consist of administrative 
payroll and related benefit charges, advertising and promotional expenses, 
administrative travel and allocable expenses (facility charges and 
information technology costs). Advertising expense is recognized as incurred. 

   Taxes on Income 
   Covance uses the asset and liability method of accounting for income 
taxes. Under this method, deferred tax assets and liabilities are recognized 
for the expected future tax consequences of differences between the carrying 
amounts of assets and liabilities and their respective tax bases using 
enacted tax rates in effect for the year in which the temporary differences 
are expected to reverse. The effect on deferred taxes of a change in enacted 
tax rates is recognized in income in the period when the change is effective. 

3. Property and Equipment 
   Property and equipment at December 31, 1995 and 1994 consist of the 
following: 

                                                         1995         1994 
                                                       ---------    --------- 
Property and equipment at cost: 
 Land                                                  $   2,996    $   2,746 
 Buildings and improvements                              105,291       94,549 
 Equipment                                               101,686       90,117 
 Furniture, fixtures & leasehold improvements             39,622       36,393 
 Construction-in-progress                                  5,861        6,486 
                                                       ---------    --------- 
                                                         255,456      230,291 
Less: Accumulated depreciation and amortization         (114,748)    (103,808) 
                                                       ---------    --------- 
Property and equipment                                 $ 140,708    $ 126,483 
                                                       =========    ========= 

   Depreciation and amortization expense aggregated $20.8 million, $17.8 
million and $16.5 million for 1995, 1994 and 1993, respectively. 

4. Acquisitions and Goodwill 
   In April 1994, Covance acquired SciCor S.A., a provider of laboratory 
testing services domiciled in Switzerland, for total consideration of 
approximately $10.8 million in a transaction accounted for as a purchase 
business combination. The goodwill resulting from this transaction aggregated 
$9.5 million. 

   
   In January 1995, Covance acquired National Packaging Systems, Inc. ("NPS", 
now known as Covance Pharmaceutical Packaging Services Inc.) for an initial 
cash payment of $14.0 million in a transaction accounted for as a purchase 
business combination. The goodwill resulting from this transaction aggregated 
$9.1 million. In accordance with the terms of the acquisition agreement, 
Covance is contingently obligated to pay up to an additional $7.0 million in 
contingent purchase price to former NPS shareholders if NPS achieves certain 
established earnings targets for the period January 1995 through September 
1996. 
    

   Results of operations for these entities have been included in the 
accompanying financial statements beginning on the respective dates of 
acquisition. Pro forma information for these entities has not been presented, 
due to their insignificance to Covance taken as a whole. 

   Goodwill associated with these and prior acquisitions aggregated $24.0 
million and $15.9 million, net of accumulated amortization of $3.5 million 
and $2.6 million at December 31, 1995 and 1994, respectively. Amortization 
expense aggregated $0.9 million, $0.5 million and $0.3 million for 1995, 1994 
and 1993, respectively. 

                                     F-36 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
              NOTES TO COMBINED FINANCIAL STATEMENTS (Continued) 
              (Dollars in thousands, unless otherwise indicated) 

5. Taxes on Income 
   Covance has been included in the Federal income tax return filed by 
Corning. Covance and its subsidiaries have a tax sharing agreement with 
Corning, pursuant to which they are required to compute their provision for 
income taxes on a separate return basis and pay to Corning the separate 
Federal income tax return liability so computed. 

   The components of income before taxes and the related provision (benefit) 
for taxes on income were as follows: 

                                          1995     1994      1993 
                                        -------   -------   ------- 
Income before taxes and equity 
  investee losses: 
 Domestic                               $32,771   $30,928   $29,455 
 International                           10,305     4,076     2,253 
                                        -------   -------   ------- 
  Total                                 $43,076   $35,004   $31,708 
                                        =======   =======   ======= 
Federal income taxes: 
 Current provision                      $19,118   $12,167   $10,932 
 Deferred benefit                        (6,760)   (1,742)   (1,439) 
International income taxes: 
 Current (benefit) provision               (933)      602      (573) 
 Deferred provision                       3,434     1,440     1,612 
State and other income taxes: 
 Current provision                        3,959     2,868     3,143 
 Deferred benefit                          (373)     (411)     (169) 
                                        -------   -------   ------- 
  Total                                 $18,445   $14,924   $13,506 
                                        =======   =======   ======= 

   The differences between the provision for income taxes and income taxes 
computed using the Federal income tax rate were as follows: 

                                          1995     1994      1993 
                                        --------  ----------------- 

Taxes at statutory rate                   35.0%    35.0%     35.0% 
State and local taxes, net of Federal 
  benefit                                  5.5      4.6       6.1 
Impact of international operations        (0.3)     1.7       0.8 
Goodwill amortization                      1.1      0.5       0.4 
Other, net                                 1.5      0.8       0.3 
                                          ----     ----      ----   
 Total                                    42.8%    42.6%     42.6% 
                                          ====     ====      ====   

   The tax effects of temporary differences that give rise to significant 
portions of the deferred tax assets and liabilities at December 31, 1995 and 
1994 are as follows: 


                                             1995         1994 
                                           --------     --------  
Current deferred taxes: 
 Liabilities not currently deductible      $ 10,356     $  9,823 
 Net operating losses                           888           -- 
 Other                                          538          210 
                                           --------     --------  
                                             11,782       10,033 
 Less: valuation allowance                     (445)          -- 
                                           --------     --------  
 Net                                       $ 11,337     $ 10,033 
                                           ========     ========  
Noncurrent deferred taxes: 
 Property and equipment                    $(12,263)    $(11,894) 
 Liabilities not currently deductible         5,857        2,289 
                                           --------     --------  
  Total                                    $ (6,406)    $ (9,605) 
                                           ========     ========  

                                     F-37 
<PAGE> 

                          COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
              NOTES TO COMBINED FINANCIAL STATEMENTS (Continued) 
              (Dollars in thousands, unless otherwise indicated) 

   Income taxes payable at December 31, 1995 and 1994 consists of Federal 
income taxes payable to Corning of $17.0 million and $8.7 million, 
respectively, state and other income taxes payable (receivable) of $1.6 
million and $(0.4) million, respectively, and international income taxes 
receivable of $2.0 million and $0.4 million, respectively. Covance paid 
income taxes of $16.7 million, $17.0 million and $18.3 million for the years 
1995, 1994 and 1993, respectively. 

6. Employee Benefit Plans 
   Covance has several defined contribution plans covering substantially all 
of its full-time employees. Contributions to these plans aggregated $4.9 
million, $4.2 million and $3.7 million for 1995, 1994 and 1993, respectively. 

7. Restructuring Charge 
   In 1995, Covance recorded a provision for restructuring charges totaling 
$4.6 million as a result of management's decision to discontinue certain 
nonstrategic operations. The restructuring charge included severance costs 
related to approximately 90 employees, of which approximately 50 had been 
terminated as of December 31, 1995. The remaining employees were terminated 
and all other substantive activities to complete the restructuring plan were 
completed by April 30, 1996. A summary of the restructuring charge is as 
follows: 

                                                    Charges      Reserve 
                                                    through    balance at 
                                        Original   December     December 
                                        Reserve    31, 1995     31, 1995 
                                        --------   --------    ----------
Employee termination costs               $1,480     $  539       $  941 
Write-off of fixed assets                 1,737        994          743 
Costs of exiting leased facilities        1,399        118        1,281 
                                         ------     ------       ------ 
 Total                                   $4,616     $1,651       $2,965 
                                         ======     ======       ====== 

8. Commitments and Contingent Liabilities 
   Minimum rental commitments under noncancellable operating leases, 
primarily real estate and office facilities, in effect at December 31, 1995 
are as follows: 

Year ended December 31, 
1996                        $15,332 
1997                        $18,841 
1998                        $16,578 
1999                        $15,493 
2000                        $14,394 
2001 and beyond             $31,253 

   Operating lease rental expense aggregated $14.1 million, $11.0 million and 
$9.1 million for 1995, 1994 and 1993, respectively. 

   In June 1995, Covance Biotechnology ("lessee") entered into a lease 
arrangement whereby a custom-designed, fully equipped facility would be 
constructed for the lessee at a cost of approximately $55 million to perform 
specialized research and manufacturing activities for biotechnology and 
pharmaceutical companies. The lessor in this arrangement is a subsidiary of 
one of the largest banks in the United States. The lease arrangement contains 
purchase and cancellation options for the lessee at any time during the ten 
year period covered by the lease arrangement. Although the lease arrangement 
is cancelable by the lessee at any time throughout the ten year period, an 
initial lease term of five years, representing management's estimate at the 
lease inception date of the period in 


                                     F-38 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
              NOTES TO COMBINED FINANCIAL STATEMENTS (Continued) 
              (Dollars in thousands, unless otherwise indicated) 

which occupancy of the facility is reasonably assured, has been selected for 
financial reporting purposes. The initial term of the lease will commence on 
the date of completion of construction of the facility which is currently 
anticipated by the end of 1996. The annual minimum lease payments are 
currently estimated at $5.5 million. The lease arrangement will be classified 
as an operating lease. 

A purchase price option has been established at specific dates over the ten 
year period covered by the lease arrangement. Using current estimates, the 
purchase price would approximate $54 million at the end of the first year and 
decreases on an amortizing basis to approximately $37 million at the end of 
the tenth year. 

The cancellation option provisions of the lease arrangement stipulate a 
residual value guarantee by Covance at specific dates over the ten year 
period. Sale of the facility is stipulated in the lease arrangement at such 
time that the lessee exercises the cancellation option provisions. The 
lessee's residual value guarantee ("Deficiency Payment") is unconditionally 
payable to the lessor in the event that the lessee terminates the lease 
arrangement and the sale of the facility results in receipt of sales proceeds 
by the lessor in an amount less than the lessor's unamortized investment in 
the lease arrangement. The lessee's maximum Deficiency Payment would 
approximate $35 million at the end of the first year and decreases to 
approximately $25 million at the end of the tenth year, assuming that the 
sales proceeds received by the lessor were zero. 

9. Geographic Information 

                              United 
                              States        Europe 
                          -------------- ----------- 
Net revenue: 
 1995                       $286,474       $122,700 
 1994                       $242,131       $ 77,370 
 1993                       $227,110       $ 62,587 
Income from operations: 
 1995                       $ 34,799 (1)   $ 12,762 
 1994                       $ 32,710       $  5,889 
 1993                       $ 32,673       $  4,308 
Identifiable assets: 
 1995                       $229,720       $ 92,790 
 1994                       $202,986       $ 69,006 
 1993                       $183,652       $ 46,041 

 (1) Excluding the impact of the 1995 restructuring provision totaling 
     $4,616, United States income from operations was $39,415. 

10. Related Party Transactions 
   Covance participates in Corning's centralized treasury and cash management 
processes. For domestic operations, cash received from operations is 
generally transferred to Corning on a daily basis. For international 
operations, excess cash is periodically transferred to Corning. Cash 
disbursements for operations, acquisitions and other investments are funded 
as needed from Corning. Substantially all of Covance's borrowings to date 
have been with Corning. The blended rate on those borrowings for 1995, 1994 
and 1993 was approximately 6.0%. 

   Certain members of Covance management participate in various stock 
compensation programs sponsored by Corning. The expenses associated with 
these programs have been reflected in the accompanying financial statements. 

   Corning and affiliates provide a number of administrative functions to 
Covance which resulted in charges of $5.3 million, $5.7 million and $5.3 
million being recorded in the Covance results of operations for 1995, 1994 
and 1993, respectively. Management believes the method used to allocate such 
costs is reasonable under the circumstances. The charges for these functions 
are included primarily in selling, general and administrative expenses 


                                     F-39 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
              NOTES TO COMBINED FINANCIAL STATEMENTS (Continued) 
              (Dollars in thousands, unless otherwise indicated) 

and do not necessarily reflect the amount of expenses that would have been 
incurred by Covance on a stand-alone basis. Covance management believes that 
these costs would have been approximately $2.0 million higher on an annual 
basis had Covance operated as a stand alone company during this period. In 
certain cases, related party expenses allocated to Covance have not required 
reimbursement in cash and, accordingly, have been treated as a capital 
contribution. 

   
11. Subsequent Event 
   In March 1996, Covance acquired all of the assets and substantially all of 
the liabilities of Health Technology Associates, Inc. ("HTA", now known as 
Covance Health Economics and Outcomes Services Inc.) for an initial cash 
payment of approximately $15.0 million in a transaction accounted for as a 
purchase business combination. In accordance with the terms of the asset 
purchase agreement, Covance is contingently obligated to pay up to an 
additional $17.0 million in contingent purchase price if HTA achieves certain 
established earnings targets for the three year period ending March 1999. 
    

   In conjunction with the Covance Spin-Off Distribution, Covance plans to 
record a material nonrecurring charge at the distribution date related to 
establishing and funding an employee stock ownership plan, other employee 
benefit plan arrangements and costs for advisors and other fees associated 
with being established as a separate publicly traded entity. In addition, 
Covance plans to incur significant long term bank borrowings to repay Corning 
for all intercompany borrowings and income tax liabilities at the 
distribution date. The credit facility governing such borrowings prohibits 
Covance from paying cash dividends on the Covance stock. 

   Corning, Corning Clinical Laboratories Inc. ("CCL") and Covance will enter 
into tax indemnification agreements that will prohibit CCL and Covance for a 
period of two years after the Distributions from taking certain actions that 
might jeopardize the favorable tax treatment of the Distributions under 
Section 355 of the Internal Revenue Code of 1986, as amended and will provide 
Corning and CCL with certain rights of indemnification against CCL and 
Covance. The tax indemnification agreements will also require CCL and Covance 
to take such actions as Corning may request to preserve the favorable tax 
treatment provided for in any rulings obtained from the Internal Revenue 
Service in respect of the Distributions. 

   Corning, CCL and Covance will also enter into a tax sharing agreement 
which will allocate among Corning, CCL and Covance responsibility for 
federal, state and local taxes relating to taxable periods before and after 
the Spin-Off Distributions and provide for computing and apportioning tax 
liabilities and tax benefits for such periods among the parties. 

12. Quarterly Financial Information (Unaudited) 
   The following is a summary of unaudited quarterly financial information 
for 1995 and 1994: 

                                  First      Second      Third       Fourth 
Year Ended December 31, 1995     Quarter    Quarter     Quarter     Quarter 
- ----------------------------     -------    -------     -------     ------- 
Net revenues                     $91,974    $104,813    $106,099    $106,288 
Income from operations            12,983       9,665(1)   13,671      11,242 
Net income                         6,547       4,449(1)    7,516       5,714 

Year Ended December 31, 1994 
- ----------------------------
Net revenues                     $74,223    $ 77,762    $ 82,904    $ 84,612 
Income from operations             8,187      11,077       9,690       9,645 
Net income                         4,023       5,726       4,967       4,929 

   (1) Excluding the impact of the 1995 restructuring provision totaling 
       $4,616 ($2,770 net of tax), income from operations and net income in 
       the second quarter of 1995 were $14,281 and $7,219, respectively. 

                                     F-40 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
                       INTERIM COMBINED BALANCE SHEETS 
             SEPTEMBER 30, 1996 AND DECEMBER 31, 1995 (UNAUDITED) 


(Amounts in thousands)                              1996        1995 
                                                  --------    -------- 
Assets 
Current Assets: 
 Cash and cash equivalents                        $ 13,551    $  8,068 
 Accounts receivable, net                           95,690      78,968 
 Unbilled services                                  43,110      18,217 
 Inventory                                          14,718      14,004 
 Deferred income taxes                              14,273      11,337 
 Prepaid expenses and other assets                  20,639      15,189 
                                                  --------    -------- 
  Total Current Assets                             201,981     145,783 
 Property and Equipment, net                       143,956     140,708 
 Goodwill, net                                      43,443      24,028 
 Other Assets                                       13,212      11,991 
                                                  --------    -------- 
  Total Assets                                    $402,592    $322,510 
                                                  ========    ======== 
Liabilities and Stockholder's Equity 
Current Liabilities: 
 Trade accounts payable                           $ 23,627    $ 23,761 
 Accrued payroll and benefits                       30,058      20,339 
 Accrued expenses and other liabilities             36,410      24,701 
 Unearned revenue                                   46,025      41,879 
 Income taxes payable                               18,408      16,631 
                                                  --------    -------- 
  Total Current Liabilities                        154,528     127,311 
Due to Corning Incorporated and affiliates         118,165      89,836 
Deferred income taxes                                9,583       6,406 
Other liabilities                                   14,444      16,440 
                                                  --------    -------- 
  Total Liabilities                                296,720     239,993 
                                                  --------    -------- 
Commitments and Contingent Liabilities 
Stockholder's Equity: 
 Contributed capital                                32,368      30,816 
 Retained earnings                                  70,505      48,653 
 Cumulative translation adjustment                   2,999       3,048 
                                                  --------    -------- 
  Total Stockholder's Equity                       105,872      82,517 
                                                  --------    -------- 
   Total Liabilities and Stockholder's Equity     $402,592    $322,510 
                                                  ========    ======== 

  The accompanying notes are an integral part of these financial statements. 

                                     F-41 
<PAGE> 



                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
                    INTERIM COMBINED STATEMENTS OF INCOME 
 FOR THE THREE AND NINE MONTHS ENDED SEPTEMBER 30, 1996 AND 1995 (UNAUDITED) 


<TABLE>
<CAPTION>
                                            Three Months Ended      Nine Months Ended 
                                            -------------------    -------------------- 
(Amounts in thousands)                        1996        1995       1996        1995 
                                            --------    ---------  --------    -------- 
<S>                                         <C>         <C>        <C>         <C>      
Net revenues                                $127,179    $106,099   $357,406    $302,886 
Cost and expenses 
  Cost of revenue                             83,204      70,057    232,828     198,820 
  Selling, general and administrative 
   expenses                                   20,627      16,882     57,573      46,965 
  Restructuring charge                            --          --         --       4,616 
  Depreciation and amortization                5,846       5,489     18,130      16,166 
                                            --------    ---------  --------    -------- 
    Total                                    109,677      92,428    308,531     266,567 
                                            --------    ---------  --------    -------- 
Income from operations                        17,502      13,671     48,875      36,319 
                                            --------    ---------  --------    -------- 
Other expense 
  Interest expense, net                        1,871       1,167      4,536       3,918 
  Foreign exchange loss                         (321)       (936)      (212)       (609) 
                                            --------    ---------  --------    -------- 
                                               1,550         231      4,324       3,309 
                                            --------    ---------  --------    -------- 
Income before taxes and equity investee 
  losses                                      15,952      13,440     44,551      33,010 
Taxes on income                                6,931       5,771     19,411      14,147 
Equity investee loss (gain)                      (53)        153        (68)        351 
                                            --------    ---------  --------    -------- 
Net income                                  $  9,074    $   7,516  $ 25,208    $ 18,512 
                                            ========    =========  ========    ======== 
</TABLE>

  The accompanying notes are an integral part of these financial statements. 

                                     F-42 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
                  INTERIM COMBINED STATEMENTS OF CASH FLOWS 
      FOR THE NINE MONTHS ENDED SEPTEMBER 30, 1996 AND 1995 (UNAUDITED) 


(Amounts in thousands)                                  1996        1995 
                                                     --------    -------- 
Cash flows from operating activities 
Net income                                           $ 25,208    $ 18,512 
Adjustments to reconcile net income to net cash 
  provided by operating activities: Depreciation 
  and amortization                                     18,130      16,166 
  Restructuring reserve, net of cash paid                  --       3,749 
  Deferred income tax provision                           241      (3,867) 
  Related party charges                                 1,552       2,406 
  Other                                                   162         901 
Changes in operating assets and liabilities: 
  Accounts receivable                                 (14,987)     (8,741) 
  Unbilled services                                   (22,365)    (10,738) 
  Inventory                                              (714)     (2,069) 
  Accounts payable                                       (177)     (4,208) 
  Accrued liabilities                                  12,084      15,923 
  Unearned revenue                                      2,932       2,419 
  Income taxes payable                                  1,777       5,948 
  Other assets and liabilities, net                    (8,922)     (3,987) 
                                                     --------    -------- 
Net cash provided by operating activities              14,921      32,414 
                                                     --------    -------- 
Cash flows from investing activities 
  Capital expenditures                                (19,977)    (25,209) 
  Acquisition of businesses                           (14,890)    (14,000) 
  Other, net                                              458         398 
                                                     --------    -------- 
Net cash used in investing activities                 (34,409)    (38,811) 
                                                     --------    -------- 
Cash flows from financing activities 
  Due to Corning Incorporated and affiliates           13,439       8,111 
  Acquisition loan from Corning Incorporated           14,890      14,000 
  Capital contributions                                    --       1,000 
  Dividends paid                                       (3,358)    (10,257) 
                                                     --------    -------- 
NET CASH PROVIDED BY FINANCING ACTIVITIES              24,971      12,854 
                                                     --------    -------- 
NET CHANGE IN CASH AND CASH EQUIVALENTS                 5,483       6,457 
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD          8,068       6,176 
                                                     --------    -------- 
CASH AND CASH EQUIVALENTS, END OF PERIOD             $ 13,551    $ 12,633 
                                                     ========    ======== 

  The accompanying notes are an integral part of these financial statements. 

                                     F-43 
<PAGE> 

                        COVANCE INC. AND SUBSIDIARIES 
         (an indirect wholly-owned business of Corning Incorporated) 
                    NOTES TO COMBINED FINANCIAL STATEMENTS 
                                 (Unaudited) 

1. Basis of Presentation 
   The accompanying unaudited combined financial statements reflect all 
adjustments which, in the opinion of management, are necessary for a fair 
statement of the results of operations for the interim periods presented. All 
such adjustments are of a normal recurring nature. The combined financial 
statements have been compiled without audit and are subject to such year-end 
adjustments as may be considered appropriate and should be read in 
conjunction with the historical combined financial statements of Covance for 
the years ended December 31, 1995, 1994 and 1993 included elsewhere herein. 

2. Use of Estimates 
   The preparation of these unaudited combined financial statements in 
conformity with generally accepted accounting principles requires management 
to make estimates and assumptions that affect the reported amounts of assets 
and liabilities, disclosure of contingent assets and liabilities at the date 
of the financial statements and the reported amounts of revenues and expenses 
during the reporting period. Actual results could differ from these 
estimates. 

3. Taxes on Income 
   Taxes on income reflect the estimated annual effective tax rates. 

   
4. Acquisitions 
   In March 1996, Covance acquired all of the assets and substantially all of 
the liabilities of Health Technology Associates, Inc. ("HTA", now known as 
Covance Health Economics and Outcomes Services Inc.) for an initial cash 
payment of approximately $15.0 million in a transaction accounted for as a 
purchase business combination. In accordance with the terms of the asset 
purchase agreement, Covance is contingently obligated to pay up to an 
additional $17.0 million in contingent purchase price if HTA achieves certain 
established earnings targets during the three year period ending March 1999. 

5. Subsequent Event 
   In October 1996, Covance acquired the stock of CRS Pacamed AG (now known 
as Covance Pharmaceutical Packaging Services Inc.) for a cash payment of 
approximately $14.4 million in a transaction to be accounted for as a 
purchase business combination. 
    

                                     F-44 



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