INSURED MUNICIPALS INCOME TRUST & IN QU TAX EX TR MUL SE 301
497J, 1998-05-29
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May 27, 1998



Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549-1004
Attn:  Filing Desk, Stop 1-4

            Re: Insured Municipals Income Trust & Investors' Quality
                          Tax-Exempt Trust, Series 301
                     (File No. 333-45159) (CIK No.1024816)

Gentlemen:
In accordance with the provisions of Rule 497(j) of Regulation C under the
Securities Act of 1933 (the "Securities Act") this letter serves to certify that
the most recent amendment to the registration statement of Form S-6 for the
above captioned Trust does not differ from that which would have been filed
pursuant to Rule 497(b) of the Securities Act. Amendment No. 1 to the
registration statement, which was the most recent amendment to the registration
statement, was filed electronically with the Commission on May 22, 1998.


Very truly yours,



VAN KAMPEN AMERICAN CAPITAL DISTRIBUTORS, INC.


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