INSURED MUNICIPALS INCOME TRUST & IN QU TAX EX TR MUL SE 301, 497J, 1999-08-30

INSURED MUNICIPALS INCOME TRUST & IN QU TAX EX TR MUL SE 301
497J, 1999-08-30

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                            August 30, 1999



Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C.  20549-1004

Attn:  Filing Desk - Stop 1-4

     Re:  Insured  Municipals  Income Trust and Investors'  Quality  Tax-
          Exempt Trust, Multi-Series 291
          File No. 333-45159   CIK #1024816

Ladies/Gentlemen:

         In accordance with the provisions of Rule 497(j) of Regulation C under
the Securities Act of 1933 (the "Securities Act") this letter serves to certify
that the most recent amendment to the Post-Effective of the subject Registration
Statement on Form S-6 for the above captioned Trust does not differ from that
which would have been filed pursuant to Rule 497(b) of the Securities Act. The
most recent amendment to the Registration Statement was filed electronically
with the commission on August 25, 1999.

                                    Very truly yours,




                                    Van Kampen Funds Inc.