Consent of Independent Certified Public Accountants

     We have issued our report dated September 15, 2000 accompanying the
financial statements of Van Kampen Focus Portfolios, Municipal Series 321 as of
July 31, 2000, and for the period then ended, contained in this Post-Effective
Amendment No. 1 to Form S-6.

   We consent to the use of the aforementioned report in the Post-Effective
Amendment and to the use of our name as it appears under the caption "Auditors".

                                                Grant Thornton LLP


Chicago, Illinois
November 22, 2000



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