VAN KAMPEN AMERICAN CAPITAL EQUITY OPPORTUNITY TRUST SER 65
S-6EL24, 1997-07-10
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File No:  333-
CIK #1025211

                   Securities and Exchange Commission
                      Washington, D.C.  20549-1004
                                Form S-6

For Registration under the Securities Act of 1933 of Securities of Unit
Investment Trusts Registered on Form N-8B-2.

A. Exact name of Trust:  Van Kampen American Capital Equity
                         Opportunity Trust, Series 65

B. Name of Depositor:    Van Kampen American Capital Distributors, Inc.

C. Complete address of Depositor's principal executive offices:

   One Parkview Plaza
   Oakbrook Terrace Illinois  60181

D. Name and complete address of agents for service:

Chapman And Cutler           Van Kampen American Capital Distributors, Inc.
Attention:  Mark J. Kneedy   Attention:  Don G. Powell, Chairman
111 West Monroe Street       One Parkview Plaza
Chicago, Illinois  60603     Oakbrook Terrace, Illinois  60181

E. Title and amount of securities being registered:  An indefinite number
   of Units of undivided fractional beneficial interests pursuant to Rule
   24f-2 under the Investment Company Act of 1940

F. Proposed maximum offering price to the public of the securities being
   registered:  Indefinite

G. Amount of registration fee: Not Applicable

H. Approximate date of proposed sale to the public:

   As Soon As Practicable After The Effective Date Of The Registration
                                Statement
____________________________________________
The registrant hereby amends this Registration Statement on such date or
dates  as may be necessary to delay its effective date until  the
registrant shall file a further amendment which specifically states that
this Registration Statement shall thereafter become effective  in
accordance with Section 8(a) of the Securities Act of 1933 or until the
Registration Statement shall become effective on such date as the
Commission, acting pursuant to said Section 8(a) may determine.



          Van Kampen American Capital Equity Opportunity Trust
                                Series 65
                          Cross Reference Sheet

                 Pursuant to Rule 404(c) of Regulation C
                    under the Securities Act of 1933
               (Form N-8B-2 Items Required by Instruction
                     1 as to Prospectus on Form S-6)

Form N-8B-2                                     Form S-6
Item Number                              Heading in Prospectus

                I.  Organization and General Information

 1. (a)  Name of trust                 ) Prospectus Front Cover Page

    (b)  Title of securities issued    ) Prospectus Front Cover Page

 2. Name and address of Depositor      ) Summary of Essential Financial
                                       ) Information
                                       ) Trust Administration

 3. Name and address of Trustee        ) Summary of Essential Financial
                                       ) Information
                                       ) Trust Administration

 4. Name and address of principal      ) Trust Administration
      underwriter

 5. Organization of trust              ) The Trust

 6. Execution and termination of       ) The Trust
      Trust Indenture and Agreement    ) Trust Administration

 7. Changes of Name                    ) *
  
 8. Fiscal year                        ) *

 9. Material Litigation                ) *

                II.  General Description of the Trust and
                         Securities of the Trust

10. General information regarding      ) The Trust
      Trust's securities and           ) Federal Taxation
      rights of security holders       ) Public Offering
                                       ) Rights of Unitholders
                                       ) Trust Administration
                                       ) Risk Factors

11. Type of securities comprising      ) Prospectus Front Cover Page
      units                            ) The Trust
                                       ) Trust Portfolio
                                       ) Risk Factors

12. Certain information regarding      ) *
      periodic payment certificates    )

13. (a)  Loan, fees, charges and       ) Prospectus Front Cover Page
    expenses                           ) Summary of Essential Financial
                                       ) Information
                                       ) Trust Portfolio
                                       ) Trust Operating Expenses
                                       ) Public Offering
                                       ) Rights of Unitholders

    (b)  Certain information regarding )
           periodic payment plan       ) *
           certificates                )

    (c)  Certain percentages           ) Prospectus Front Cover Page
                                       ) Summary of Essential Financial
                                       ) Information
                                       ) Public Offering
                                       ) Rights of Unitholders

    (d)  Certain other fees, expenses  ) Trust Operating Expenses
           or charges payable by       ) Rights of Unitholders
           holders

    (e)  Certain profits to be         ) Public Offering
           received by depositor,      ) Trust Portfolio
           principal underwriter,      )      
           trustee or any affiliated   )     
           persons                     )

    (f)  Ratio of annual charges       ) *
           to income                   )

14. Issuance of Trust's securities     ) Rights of Unitholders

15. Receipt and handling of payments   ) *
      from purchasers                  )

16. Acquisition and disposition of     ) The Trust
      underlying securities            ) Rights of Unitholders
                                       ) Trust Administration

17. Withdrawal or redemption           ) Rights of Unitholders
                                       ) Trust Administration
18. (a)  Receipt and disposition       ) Prospectus Front Cover Page
           of income                   ) Rights of Unitholders

    (b)  Reinvestment of distributions)    *

    (c)  Reserves or special funds     ) Trust Operating Expenses
                                       ) Rights of Unitholders
    (d)  Schedule of distributions     ) *

19. Records, accounts and reports      ) Rights of Unitholders
                                       ) Trust Administration

20. Certain miscellaneous provisions   ) Trust Administration
      of Trust Agreement               )

21. Loans to security holders          ) *

22. Limitations on liability           ) Trust Portfolio
                                       ) Trust Administration
23. Bonding arrangements               ) *

24. Other material provisions of       ) *
    Trust Indenture Agreement          )
  
              III.  Organization, Personnel and Affiliated
                          Persons of Depositor

25. Organization of Depositor          ) Trust Administration
  
26. Fees received by Depositor         ) *

27. Business of Depositor              ) Trust Administration

28. Certain information as to          ) *
      officials and affiliated         )
      persons of Depositor             )

29. Companies owning securities        ) *
      of Depositor                     )

30. Controlling persons of Depositor   ) *

31. Compensation of Officers of        ) *
      Depositor                        )

32. Compensation of Directors          ) *

33. Compensation to Employees          ) *

34. Compensation to other persons      ) *

             IV.  Distribution and Redemption of Securities

35. Distribution of trust's securities ) Public Offering
      by states                        )

36. Suspension of sales of trust's     ) *
      securities                       )

37. Revocation of authority to         ) *
      distribute                       )

38. (a)  Method of distribution        )
                                       )
    (b)  Underwriting agreements       ) Public Offering
                                       )
    (c)  Selling agreements            )

39. (a)  Organization of principal     ) *
           underwriter                 )

    (b)  N.A.S.D. membership by        ) *
           principal underwriter       )

40. Certain fees received by           ) *
      principal underwriter            )

41. (a)  Business of principal         ) Trust Administration
           underwriter                 )

    (b)  Branch offices or principal   ) *
           underwriter                 )

    (c)  Salesmen or principal         ) *
           underwriter                 )

42. Ownership of securities of         ) *
      the trust                        )

43. Certain brokerage commissions      ) *
      received by principal underwriter)

44. (a)  Method of valuation           ) Prospectus Front Cover Page
                                       ) Summary of Essential Financial
                                       ) Information
                                       ) Trust Operating Expenses
                                       ) Public Offering

    (b)  Schedule as to offering       ) *
           price                       )

    (c)  Variation in offering price   ) *
           to certain persons          )

46. (a)  Redemption valuation          ) Rights of Unitholders
                                       ) Trust Administration
    (b)  Schedule as to redemption     ) *
           price                       )

47. Purchase and sale of interests     ) Public Offering
      in underlying securities         ) Trust Administration

           V.  Information Concerning the Trustee or Custodian

48. Organization and regulation of     ) Trust Administration
      trustee                          )

49. Fees and expenses of trustee       ) Summary of Essential Financial
                                       ) Information
                                       ) Trust Operating Expenses

50. Trustee's lien                     ) Trust Operating Expenses
                                    
     VI.  Information Concerning Insurance of Holders of Securities

51. Insurance of holders of trust's    )
      securities                       ) *

52. (a)  Provisions of trust agreement )
           with respect to replacement ) Trust Administration
           or elimination portfolio    )
           securities                  )

    (b)  Transactions involving        )
           elimination of underlying   ) *
           securities                  )

    (c)  Policy regarding substitution )
           or elimination of underlying) Trust Administration
           securities                  )

    (d)  Fundamental policy not        ) *
           otherwise covered           )

53. Tax Status of trust                ) Federal Taxation

               VII.  Financial and Statistical Information

54. Trust's securities during          ) *
      last ten years                   )

55.                                    )

56. Certain information regarding      ) *

57.   periodic payment certificates    )

58.                                    )

59. Financial statements (Instructions ) Report of Independent Certified
      1(c) to Form S-6)                ) Public Accountants
                                       ) Statement of Condition

______________________________________________
* Inapplicable, omitted, answer negative or not required


                                    
               Preliminary Prospectus Dated July 10, 1997
                                    
          Van Kampen American Capital Equity Opportunity Trust
                                    
                                                             Series 65
                                             (A Unit Investment Trust)
     
     The attached final Prospectus for a prior Series of the Trust is
hereby used as a preliminary Prospectus for the above stated Series.  The
narrative information and structure of the attached final Prospectus will
be substantially the same as that of the final Prospectus for this
Series.  Information with respect to pricing, the number of Units, dates
and summary information regarding the characteristics of securities to be
deposited in this Series is not now available and will be different since
each  Series has a unique Portfolio.  Accordingly the information
contained herein with regard to the previous Series should be considered
as being included for informational purposes only.
     
     A registration statement relating to the units of this Series will
be filed with the Securities and Exchange Commission but has not yet
become effective.  Information contained herein is subject to completion
or amendment.  Such Units may not be sold nor may offer to buy be
accepted prior to the time the registration statement becomes effective.
This Prospectus shall not constitute an offer to sell or the solicitation
of an offer to buy nor shall there be any sale of the Units in any state
in which such offer, solicitation or sale would be unlawful prior to
registration or qualification under the securities laws of any such
state.

(Incorporated herein by reference is the final prospectus from Van Kampen
American Capital Equity Opportunity Trust, Series 57 (Registration No.
333-24723) as filed on June 24, 1997, which shall be  used  as  a
preliminary prospectus for the current Series of the Trust.)


                   Contents Of Registration Statement

This Registration Statement comprises the following papers and documents:

      The facing sheet
      The Cross-Reference Sheet
      The Prospectus
      The signatures
      The consents of independent public accountants
        and legal counsel

The following exhibits:

1.1   Proposed form of Trust Agreement (to be supplied by amendment).

3.1   Opinion and consent of counsel as to legality of securities being
      registered (to be supplied by amendment).

3.2   Opinion of counsel as to Federal income tax status of securities
      being registered (to be supplied by amendment).

3.3   Opinion and consent of counsel as to New York tax status of
      securities being registered (to be supplied by amendment).

4.1   Consent of Interactive Data Corporation (to be supplied by
      amendment).

4.2   Consent of Grant Thornton LLP (to be supplied by amendment).

EX-27 Financial Data Schedule (to be supplied by amendment).

                               Signatures
     
     Pursuant to the requirements of the Securities Act of 1933, the
Registrant, Van Kampen American Capital Equity Opportunity Trust, Series
65 has duly caused this Registration Statement to be signed on its behalf
by the undersigned, thereunto duly authorized in the City of Chicago and
State of Illinois on the 10th day of July, 1997.
                                    
                                    Van Kampen American Capital Equity
                                       Opportunity Trust, Series 65
                                       (Registrant)
                                    
                                    By Van Kampen American Capital
                                       Distributors, Inc.
                                       (Depositor)
                                    
                                    
                                    Gina M. Costello
                                    Assistant Secretary
     
     Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed below on July 10, 1997 by the
following persons who constitute a majority of the Board of Directors of
Van Kampen American Capital Distributors, Inc.

  Signature              Title

Don G. Powell         Chairman and Chief Executive  )
                      Officer                       )


William R. Molinari   President and Chief Operating )
                      Officer

Ronald A. Nyberg      Executive Vice President and  )
                      General Counsel

William R. Rybak      Executive Vice President and  )
                      Chief Financial Officer       )

Gina M. Costello                                    ) (Attorney-in-fact*)


     *An executed copy of each of the related powers of attorney was
filed with the Securities and Exchange Commission in connection with the
Registration Statement on Form S-6 of Insured Municipals Income Trust and
Investors' Quality Tax-Exempt Trust, Multi-Series 203 (File No. 33-65744)
and with the Registration Statement on Form S-6 of Insured Municipals
Income Trust, 170th Insured Multi-Series (File No. 33-55891) and the same
are hereby incorporated herein by this reference.


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