VAN KAMPEN AMERICAN CAPITAL EQUITY OPPORTUNITY TRUST SER 121
497J, 1998-11-12
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                                November 11, 1998

Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549-1004

Attn:  Filing Desk, Stop 1-4

Re: Van Kampen Focus Portfolios, Series 121
(File No. 333-65637)  (CIK No. 1025270)

Gentlemen:

In accordance with the provisions of Rule 497(j) of Regulation C under the
Securities Act of 1933 (the iSecurities Acti) this letter serves to certify that
the most recent amendment to the registration statement of Form S-6 for the
above captioned Trust does not differ from that which would have been filed
pursuant to Rule 497(b) of the Securities Act. Amendment No. 1 to the
registration statement, which was the most recent amendment to the registration
statement, was filed electronically with the Commission on November 10, 1998.

                                                       Very truly yours,

                                                       Van Kampen Funds Inc.


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