<PAGE>
Apollo BioPharmaceutics, Inc.
One Kendall Square, Suite 2200
Cambridge, Massachusetts 02139
June 6, 1997
BY OVERNIGHT DELIVERY
Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, DC 20549
Re: Apollo BioPharmaceutics, Inc.
Registration Statements on Form 8-A
Gentlemen and Ladies:
Apollo BioPharmaceutics, Inc. (the "Company") hereby requests that the
Company's Registration Statement on Form 8-A, which was declared effective by
order of the Commission on March 27, 1997, be withdrawn effective immediately.
The Company makes this request because a proposed initial public offering of the
Company's securities was abandoned by the lead underwriter subsequent to
effectiveness.
If you have any questions regarding this request, please contact either
John J. Cheney, Esq. of Palmer & Dodge LLP at (617) 573-0563 or me at (617)
621-7154.
Sincerely,
APOLLO BIOPHARMACEUTICS, INC.
By: /s/ Katherine Gordon, Ph.D.
------------------------------------
Katherine Gordon, Ph.D
President and Chief Executive Officer
cc: Steven Brown (Nasdaq)