CURAGEN CORP
SC 13G, 1999-02-09
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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<PAGE>
 
                                 UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                            WASHINGTON, D.C.  20549

                                 SCHEDULE 13G

                   Under the Securities Exchange Act of 1934

                                    -------

                              CuraGen Corporation
                   -----------------------------------------
                               (Name of Issuer)

                                 Common Stock
                   -----------------------------------------
                        (Title of Class of Securities)

                                  23126R 10 1
                   -----------------------------------------
                                (CUSIP Number)

                                March 17, 1998
                   -----------------------------------------
            (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

          [_]  Rule 13d-1(b)
 
          [_]  Rule 13d-1(c)

          [x]  Rule 13d-1(d)
 

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

                               Page 1 of 9 pages
<PAGE>
 
================================
CUSIP NO.   23126R 10 1                13G
================================

================================================================================
1     NAME(S) OF REPORTING PERSON(S)                            
      S.S. OR I.R.S. IDENTIFICATION NO(S). OF ABOVE PERSON(S)   
                                                                
      Henry M. Rothberg                                         

- --------------------------------------------------------------------------------
2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP          
                                                                       (a) [_]
                                                                              
                                                                       (b) [_]
- --------------------------------------------------------------------------------
3     SEC USE ONLY                                              
                                                                


- --------------------------------------------------------------------------------
4     CITIZENSHIP OR PLACE OF ORGANIZATION                      
                                                                
      United States                                              

================================================================================
                                5     SOLE VOTING POWER       
NUMBER OF SHARES                      
                                      25,000 shares           
                               -------------------------------------------------
BENEFICIALLY                    6     SHARED VOTING POWER     
                                                              
OWNED BY                              954,496 shares (consists of (i) 10,000
                                      shares of Common Stock owned jointly by
                                      Mr. Rothberg and his wife, (ii) 634,130
                                      shares of Common Stock held by Grand
                                      Hemroc Limited Partnership, and (iii)
                                      310,366 shares of Common Stock underlying
                                      currently exercisable warrants held by
                                      Grand Hemroc Limited Partnership.) Mr.
                                      Rothberg and his wife serve as co-general
                                      partners of Grand Hemroc Limited
                                      Partnership.
                               -------------------------------------------------
EACH                            7     SOLE DISPOSITIVE POWER
                                                            
REPORTING                             25,000 shares         
                               -------------------------------------------------
PERSON                          8     SHARED DISPOSITIVE POWER
                                                              
WITH                                  954,496 shares (consists of (i) 10,000
                                      shares of Common Stock owned jointly by
                                      Mr. Rothberg and his wife, (ii) 634,130
                                      shares of Common Stock held by Grand
                                      Hemroc Limited Partnership, and (iii)
                                      310,366 shares of Common Stock underlying
                                      currently exercisable warrants held by
                                      Grand Hemroc Limited Partnership.) Mr.
                                      Rothberg and his wife serve as co-general
                                      partners of Grand Hemroc Limited
                                      Partnership.
================================================================================
 
                               Page 2 of 9 pages
<PAGE>
 
================================================================================
9         AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
 
          979,496 shares (consists of (i) 25,000 shares of Common Stock held by
          Mr. Rothberg (ii) 10,000 shares of Common Stock owned jointly by Mr.
          Rothberg and his wife, (iii) 634,130 shares of Common Stock held by
          Grand Hemroc Limited Partnership, and (iv) 310,366 shares of Common
          Stock underlying currently exercisable warrants held by Grand Hemroc
          Limited Partnership.) Mr. Rothberg and his wife serve as co-general
          partners of Grand Hemroc Limited Partnership.
- --------------------------------------------------------------------------------
10        CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
 
          Not applicable.
- --------------------------------------------------------------------------------
11        PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
 
          7.0%
- --------------------------------------------------------------------------------
12        TYPE OF REPORTING PERSON*
 
          IN
================================================================================

                               Page 3 of 9 pages
<PAGE>
 
================================
CUSIP NO.   23126R 10 1               13G
================================

================================================================================
1        NAME(S) OF REPORTING PERSON(S)
         S.S. OR I.R.S. IDENTIFICATION NO(S). OF ABOVE PERSON(S)
         
         Lillian R. Rothberg

- --------------------------------------------------------------------------------
2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
                                                                     (a)  [_]
                                                                            
                                                                     (b)  [_]
- --------------------------------------------------------------------------------
3        SEC USE ONLY
         


- --------------------------------------------------------------------------------
4        CITIZENSHIP OR PLACE OF ORGANIZATION
         
         United States

================================================================================
 
                                5     SOLE VOTING POWER   
NUMBER OF SHARES                      
                                      25,000 shares        
                               -------------------------------------------------
BENEFICIALLY                    6     SHARED VOTING POWER 
                                                          
OWNED BY                              954,496 shares (consists of (i) 10,000
                                      shares of Common Stock owned jointly by
                                      Mrs. Rothberg and her husband, (ii)
                                      634,130 shares of Common Stock held by
                                      Grand Hemroc Limited Partnership, and
                                      (iii) 310,366 shares of Common Stock
                                      underlying currently exercisable warrants
                                      held by Grand Hemroc Limited Partnership.)
                                      Mrs. Rothberg and her husband serve as co-
                                      general partners of Grand Hemroc Limited
                                      Partnership.
                               -------------------------------------------------
EACH                            7     SOLE DISPOSITIVE POWER         
                                                                     
REPORTING                             25,000 shares                  
                               -------------------------------------------------
PERSON                          8     SHARED DISPOSITIVE POWER       
                                                                     
WITH                                  954,496 shares (consists of (i) 10,000
                                      shares of Common Stock owned jointly by
                                      Mrs. Rothberg and her husband, (ii)
                                      634,130 shares of Common Stock held by
                                      Grand Hemroc Limited Partnership, and
                                      (iii) 310,366 shares of Common Stock
                                      underlying currently exercisable warrants
                                      held by Grand Hemroc Limited Partnership.)
                                      Mrs. Rothberg and her husband serve as co-
                                      general partners of Grand Hemroc Limited
                                      Partnership.
================================================================================

                               Page 4 of 9 pages
<PAGE>
 
================================================================================
 9        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
 
          979,496 shares (consists of (i) 25,000 shares of Common Stock held by
          Mrs. Rothberg, (ii) 10,000 shares of Common Stock owned jointly by
          Mrs. Rothberg and her husband, (iii) 634,130 shares of Common Stock
          held by Grand Hemroc Limited Partnership, and (iv) 310,366 shares of
          Common Stock underlying currently exercisable warrants held by Grand
          Hemroc Limited Partnership.) Mrs. Rothberg and her husband serve as 
          co-general partners of Grand Hemroc Limited Partnership.
 -------------------------------------------------------------------------------
 10       CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
 
          Not applicable.
 -------------------------------------------------------------------------------
 11       PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
 
          7.0%
- --------------------------------------------------------------------------------
 12       TYPE OF REPORTING PERSON*
 
          IN
================================================================================


Item 1(a)    Name of Issuer
             --------------

             CuraGen Corporation


Item 1(b)    Address of Issuer's Principal Executive Offices
             -----------------------------------------------

             555 Long Wharf Drive
             New Haven, CT 06511


Item 2(a)    Name of Person Filing
             ---------------------

             Henry M. Rothberg and Lillian R. Rothberg


Item 2(b)    Address of Principal Business Office or, if none, Residence
             -----------------------------------------------------------

             Laticrete International, Inc.
             One Laticrete Park North     
             Bethany, CT 06524-3423        

                               Page 5 of 9 pages
<PAGE>
 
Item 2(c)  Citizenship
           -----------

           Mr. and Mrs. Rothberg are United States citizens

Item 2(d)  Title of Class of Securities
           ----------------------------

           Common Stock
 
Item 2(e)  CUSIP Number
           ------------
           23126R 10 1

Item 3.    If this statement is filed pursuant to Rules 13d-1(b) or 13d-2(b) or
           --------------------------------------------------------------------
           (c), check whether the person filing is a
           -----------------------------------------
 
      (a)  [_]  Broker or dealer registered under Section 15 of the Act (15
                U.S.C. 78o).
 
      (b)  [_]  Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).
 
      (c)  [_]  Insurance company as defined in Section 3(a)(19) of the Act (15
                U.S.C. 78c).
                
      (d)  [_]  Investment company registered under Section 8 of the Investment
                Company Act of 1940 (15 U.S.C. 80a-8).
 
      (e)  [_]  An investment Adviser in accordance with (S)240.13d-
                1(b)(1)(ii)(E).
 
      (f)  [_]  An employee benefit plan or endowment fund in accordance with
                (S)240.13d-1(b)(1)(ii)(F).
 
      (g)  [_]  A parent holding company or control person in accordance with
                (S)240.13d-1(b)(1)(ii)(G).
 
      (h)  [_]  A savings associations as defined in Section 3(b) of the Federal
                Deposit Insurance Act (12 U.S.C. 1813).
                
      (i)  [_]  A church plan that is excluded from the definition of an
                investment company under section 3(c)(14) of the Investment
                Company Act of 1940 (15 U.S.C. 80a-3).
 
      (j)  [_]  Group, in accordance with (S)240.13d-1(b)(1)(ii)(J)

                               Page 6 of 9 pages
<PAGE>
 
Item 4.   Ownership
          ---------

     Provide the following information regarding the aggregate number and
percentage of the class of securities of the issuer identified in Item 1.

     (a)  Amount Beneficially Owned:

          Mr. Rothberg beneficially owns 979,496 shares, consisting of (i)
25,000 shares of Common Stock held by Mr. Rothberg, (ii) 10,000 shares of Common
Stock owned jointly by Mr. Rothberg and his wife, (iii) 634,130 shares of Common
Stock held by Grand Hemroc Limited Partnership, and (iv) 310,366 shares of
Common Stock underlying currently exercisable warrants held by Grand Hemroc
Limited Partnership.  Mrs. Rothberg beneficially owns 979,496 shares, consisting
of (i) 25,000 shares of Common Stock held by Mrs. Rothberg, (ii) 10,000 shares
of Common Stock owned jointly by Mrs. Rothberg and her husband, (iii) 634,130
shares of Common Stock held by Grand Hemroc Limited Partnership, and (iv)
310,366 shares of Common Stock underlying currently exercisable warrants held by
Grand Hemroc Limited Partnership.  Mr. and Mrs. Rothberg serve as co-general
partners of Grand Hemroc Limited Partnership.

     (b)  Percent of Class:

          Mr. and Mrs. Rothberg own 7.0% of the Common Stock of the Issuer.

     (c)  Number of shares as to which such person has:

          (i)    sole power to vote or to direct the vote:       
                                                              
                 Mr. Rothberg: 25,000 shares                  
                 Mrs. Rothberg: 25,000 shares                 
                                                              
          (ii)   shared power to vote or to direct the vote:  
                                                              
                 Mr. Rothberg: 954,496 shares.                
                 Mrs. Rothberg: 954,496 shares.                

          (iii)  sole power to dispose or to direct the disposition of:

                 Mr. Rothberg: 25,000 shares                             
                 Mrs. Rothberg: 25,000 shares                            
                                                                         
          (iv)   shared power to dispose or to direct the disposition of:
                                                                         
                 Mr. Rothberg: 954,496 shares.                           
                 Mrs. Rothberg: 954,496 shares.                           

                               Page 7 of 9 pages
<PAGE>
 
Item 5.   Ownership of Five Percent or Less of a Class
          --------------------------------------------


     If this statement is being filed to report the fact that as of the date
hereof the reporting person has ceased to be the beneficial owner of more than
five percent of the class of securities, check the following.  [_]


Item 6.   Ownership of More than Five Percent on Behalf of Another Person
          ---------------------------------------------------------------


     Not applicable.

Item 7.   Identification and Classification of the Subsidiary Which Acquired the
          ----------------------------------------------------------------------
          Security Being Reported on By the Parent Holding Company
          --------------------------------------------------------


     Not applicable.

Item 8.   Identification and Classification of Members of the Group
          ---------------------------------------------------------


     Not applicable.

Item 9.   Notice of Dissolution of Group
          ------------------------------


     Not applicable.

Item 10.  Certification
          -------------


     Not applicable.

                               Page 8 of 9 pages
<PAGE>
 
                                   Signature
                                   ---------

     After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.

                                                        February 2, 1999
                                                --------------------------------
                                                              (Date)


                                                      /s/ Henry M. Rothberg
                                                -------------------------------
                                                           (Signature)


                                                       Henry M. Rothberg
                                                --------------------------------
                                                        (Name and Title)

                                                     /s/ Lillian R. Rothberg
                                                --------------------------------
                                                            (Signature)


                                                       Lillian R. Rothberg
                                                 ------------------------------
                                                         (Name and Title)

Exhibit 1
                           JOINT FILING AGREEMENT OF
                   HENRY M. ROTHBERG AND LILLIAN R. ROTHBERG



          The undersigned hereby agree that the Schedule 13G with respect to the
securities of CuraGen Corporation dated as of even date herewith is filed on
behalf of each of us pursuant to and in accordance with the provisions of Rule
13d-1(k) under the Securities and Exchange Act of 1934, as amended.


Dated: February 2, 1999
 
                                                /s/ Henry M. Rothberg
                                                ---------------------------
                                                Henry M. Rothberg


                                                /s/ Lillian R. Rothberg
                                                ---------------------------
                                                Lillian R. Rothberg

                               Page 9 of 9 pages


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