<PAGE> 1
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
<TABLE>
<S> <C> <C>
- ----------------- ------------------------
FORM 4 OMB APPROVAL
- ----------------- ------------------------
------------------------
OMB NUMBER: 3235-0287
EXPIRES:
SEPTEMBER 30, 1998
ESTIMATED AVERAGE
BURDEN
HOURS PER RESPONSE...0.5
------------------------
[ ] CHECK THIS BOX
IF NO LONGER Filed pursuant to Section 16(a) of the Securities
SUBJECT TO SECTION Exchange Act of 1934, Section 17(a) of the Public Utility
16. FORM 4 OR FORM Holding Company Act of 1935 or Section 30(f) of the
5 OBLIGATIONS MAY Investment Company Act of 1940
CONTINUE. SEE
INSTRUCTION 1(B).
(Print or Type Responses)
- --------------------------------------------------------------------------------------------------------------
1. Name and Address of 2. Issuer Name and Ticker or Trading 6. Relationship of Reporting
Reporting Person* Symbol Persons to Issuer (Check
all applicable)
White, Paul J. Medical Science Systems, Inc. X Director X 10% Owner
- -------------------------------------------------------------------------- --- ---
(Last) (First) (Middle) 3. IRS or Social Security 4. Statement for ----------------- ---------------
Number of Reporting Month/Year
Person, if an entity X Officer (give Other (Specify)
100 N.E. Loop 410, Suite 1350 (Voluntary) July 1998 --- title --- below)
- ------------------------------- ------------ President, CEO & Chairman of the Board
(Street) 5. If Amendment, ----------------------------------------
Date of Original ________________________________________
San Antonio, TX 78216-4749 (Month/Year)
- -------------------------------
(City) (State) (Zip) 7. Individual or Joint/Group
Filing (Check applicable line)
X Form filed by One Reporting Person
---
Form filed by More than One Reporting
--- Person
-------------------------------------------------------------------------------------
TABLE 1 - NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
- --------------------------------------------------------------------------------------------------------------------
1. Title of Security 2. Trans- 3. Trans- 4. Securities Acquired 5. Amount of 6.Ownership 7. Nature of
(Instr. 3) action action (A) or Disposed of (D) Securities Form: Indirect
Date Code (Instr. 3, 4 and 5) Beneficially Direct Beneficial
(Instr.8) Owned at (D) or Ownership
End of Month Indirect
(Month/ (I)
Day
(Instr. 3 (Instr. 4) (Instr. 4)
and 4)
-----------------------------------
Code V Amount (A)or(D) Price
- --------------------------------------------------------------------------------------------------------------
Common Stock G 5,000 D $0.00 953,723 D
- --------------------------------------------------------------------------------------------------------------
60,000 I*
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
* These shares are held in an irrevocable trust created for the benefit of the White
children. Mr. White disclaims any beneficial ownership.
- --------------------------------------------------------------------------------------------------------------
REMINDER: REPORT ON A SEPARATE LINE FOR EACH CLASS OF SECURITIES BENEFICIALLY OWNED (Over)
DIRECTLY OR INDIRECTLY.
* IF THE FORM IS FILED BY MORE THAN ONE REPORTING PERSON, SEE INSTRUCTION 4(B)(V)
Potential persons who are to response to the collection of information contained in
this form are not required to respond unless the form displays a currently valid
OMB control number
SEC 1474 (7-96)
</TABLE>
<PAGE> 2
FORM 4
(CONTINUED)
- -------------------------------------------------------------------------------
TABLE II -- DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED
(E.G., PUTS, CALLS, WARRANTS, OPTIONS, CONVERTIBLE SECURITIES)
- -------------------------------------------------------------------------------
<TABLE>
<S> <C> <C> <C> <C> <C> <C> <C>
1. Title of 2. Conver- 3. Trans- 4. Trans- 5. Number of 6. Date Exer- 7. Title and 8. Price
Derivative sion or action action Derivative cisable and Amount of of deriv-
Security Exercise Date Code Securities Expiration Underlying ative
(Instr. 3) Price of (Month/ (Instr.8) Acquired(A) Date Securities Security
Derivative Day/ or Disposed (Month/Day/ (Instr. 3 (Instr. 5)
Security Year) of (D) (Instr. Year) and 4)
3, 4, and 5)
- -------------------------------------------------------------------------------------------------------------------
Date Expira- Amount or
Exer- tion Number of
Code V (A) (D) cisable Date Title Shares
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
9. Number of 10. Ownership 11. Nature of
derivative Form of Indirect
Securities Derivative Beneficial
Beneficially Security: Ownership
Owned Direct (D) (Instr. 4)
End of Month
(Instr. 4)
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------------------------
</TABLE>
Explanation of Responses:
Note. File three copies of this Form, one of which must be manually signed.
If space is insufficient, see Instruction 6 for procedure. SEC 1474 (7-96)
Potential persons who are to respond to the collection of information contained
in this form are not required to respond unless the form displays a currently
valid OMB Number.
/s/ PAUL J. WHITE 8-10-98
- --------------------------------------- ---------------
**Signature of Reporting Person Date
** Intentional misstatements or omissions of facts constitute Federal Criminal
Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a)
Page 2
SEC 1474 (7-96)