CHROMAVISION MEDICAL SYSTEMS INC
8-A12G/A, 1997-06-27
LABORATORY ANALYTICAL INSTRUMENTS
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<PAGE>


                                            


                          SECURITIES AND EXCHANGE COMMISSION
                                Washington, D.C. 20549
                                           
                                           
                                      Form 8-A/A
                                           
                                           
                  For Registration of Certain Classes of Securities
                       Pursuant to Section 12(b) or (g) of the
                           Securities Exchange Act of 1934
                                           
                                           
                                           
                          CHROMAVISION MEDICAL SYSTEMS, INC.
                (Exact name of registrant as specified in its charter)
                                           


                 Delaware                              75-2649072
(State of incorporation or organization)   (I.R.S. Employer Identification No.)
   
         33171 Paseo Cerveza
    San Juan Capistrano, California                       92675
(Address of principal executive offices)                (Zip Code)

                                           
          Securities to be registered pursuant to Section 12(b) of the Act:
                                           

     Title of each class                     Name of each exchange on which
     to be so registered                     each class is to be registered


          None                                        Not Applicable
          
       Securities to be registered pursuant to Section 12(g) of the Act:

                     Common Stock, par value $.01 per share
                     Subscription Rights

<PAGE>

Item 1.  Description of Registrant's Securities to be Registered  

    The Registrant is registering 7,360,000 shares of common stock, par value 
$.01 per share  (the "Common Stock"), and rights (the "Rights") to subscribe 
for 6,400,000 shares of Common Stock, pursuant to a registration statement on 
Form S-1 (File No. 333-26129) that was filed with the Securities and Exchange 
Commission on April 29, 1997, as amended (the "Registration Statement").  
Reference is made to the sections entitled "The Offering" and "Description of 
Capital Stock" in the preliminary prospectus forming a part of the 
Registration Statement, and all amendments to the Registration Statement 
subsequently filed with the Commission, including any prospectus relating 
thereto filed subsequently pursuant to Rule 424 of the Securities Act of 
1933, as amended.  Such Registration Statement and all amendments to the 
Registration Statement are hereby deemed to be incorporated by reference into 
this Registration Statement in accordance with the Instruction to Item 1 of 
this Form.

Item 2.  Exhibits
         --------

         a.   Certificate of Incorporation of the Registrant.  Reference is
              made to Exhibit 3.1 to the Registration Statement. 

         b.   By-laws of the Registrant.  Reference is made to Exhibit 3.2 to
              the Registration Statement.

         c.   Specimen certificate representing the Common Stock. *  

         d.   Specimen certificate representing the Rights. *
         ---------------------
         *  Filed herewith
         

<PAGE>

                                    SIGNATURE

    Pursuant to the requirements of Section 12 of the Securities Exchange Act 
of 1934, the Registrant has duly caused this registration statement to be 
signed on its behalf by the undersigned, thereto duly authorized.

                                     CHROMAVISION MEDICAL SYSTEMS, INC.


                                     By:  /s/ Douglas S. Harrington, M.D.
                                         --------------------------------
                                              Douglas S. Harrington, M.D.
                                    
Date:  June 27, 1997


<PAGE>

                                                                Exhibit 99.1


                                CHROMA
                              V I S I O N

   NUMBER                                                 SHARES
   CVSN-

<TABLE>
<C>                    <S>                                                       <C>
                               CHROMAVISION MEDICAL SYSTEMS, INC.
COMMON STOCK            INCORPORATED UNDER THE LAWS OF THE STATE OF DELAWARE     COMMON STOCK
                                                                                 CUSIP 17111P 10 4

THIS CERTIFIES THAT                                                              SEE REVERSE FOR
                                                                                 CERTAIN DEFINITIONS





is the owner of

</TABLE>

                    FULLY PAID AND NON-ASSESSABLE SHARES OF THE PAR VALUE OF
                    $0.01 EACH OF THE COMMON STOCK OF

                         CHROMAVISION MEDICAL SYSTEMS, INC.

transferable on the books of the Corporation by the holder hereof in person 
or by duly authorized attorney, upon surrender of this certificate properly 
endorsed. This certificate and the shares represented hereby are issued and 
shall be held subject to all of the provisions of the Articles of 
Incorporation of the Corporation and any amendments thereto. This certificate 
is not valid until countersigned by the Transfer Agent and registered by the 
Registrar.

   WITNESS the facsimile seal of the Corporation and the facsimile signatures 
of its duly authorized officers.

   Dated:

                                                    AUTHORIZED SIGNATURE

           [SIG ILLEGIBLE]                           [SIG ILLEGIBLE]
              SECRETARY                          CHIEF EXECUTIVE OFFICER


                                           COUNTERSIGNED AND REGISTERED:
                                      ChaseMellon Shareholder Services, L.L.C.

                                              TRANSFER AGENT 
                                              AND REGISTRAR



<PAGE>

ChromaVision Medical Systems, Inc. will furnish without charge to each 
stockholder who so requests the powers, designations, preferences and 
relative participating, optional or other special rights of each class of 
stock or series thereof and the qualifications, limitations or restrictions 
of such preferences and/or rights. Any such request should be addressed to 
the secretary of the Corporation.

    The following abbreviations, when used in the inscription on the face of 
this certificate, shall be construed as though they were written out in full 
according to applicable laws or regulations:

<TABLE>

<S>                                           <C>
   TEN COM -- as tenants in common             UNIFGIFTMIN ACT--___________ Custodian ___________
   TEN ENT -- as tenants by the entireties                        (Cust)                (Minor)
   JT TEN  -- as joint tenants with right                       under Uniform Gift to Minors
              of survivorship and not as 
              tenants in common                                 Act ________________________
                                                                          (State)

</TABLE>

     Additional abbreviations may also be used though not in the above list.


For value received, ______________hereby sell, assign and transfer unto

PLEASE INSERT SOCIAL SECURITY OR OTHER
    IDENTIFYING NUMBER OF ASSIGNEE
 /                                 /

- -----------------------------------------------------------------------------
 (PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS, INCLUDING ZIP CODE, OR ASSIGNEE)

- -----------------------------------------------------------------------------

- -----------------------------------------------------------------------------

- ----------------------------------------------------------------------- shares
of the common stock represented by the within Certificate, and do hereby 
irrevocably constitute and appoint

- -------------------------------------------------------------------- Attorney
to transfer the said stock on the books of the within named Corporation with 
full power of substitution in the premises.

Dated--------------------

                        ____________________________________________
                 NOTICE: THE SIGNATURE OF THIS ASSIGNMENT MUST CORRESPOND 
                         WITH THE NAME AS WRITTEN UPON THE FACE OF THE 
                         CERTIFICATE IN EVERY PARTICULAR, WITHOUT ALTERATION 
                         OR ENLARGEMENT OR ANY CHANGE WHATEVER.


SIGNATURE(S) GUARANTEED


By _______________________________________________
THE SIGNATURE(S) SHOULD BE GUARANTEED BY AN ELIGIBLE 
GUARANTOR INSTITUTION, (Banks, Stockbrokers, Savings 
and Loan Association and Credit Unions) WITH MEMBERSHIP 
IN AN APPROVED SIGNATURE GUARANTEE MEDALLION PROGRAM 
PURSUANT TO SEC RULE 17Ad-15.

<TABLE>
<S>                                               <C>
AMERICAN BANKNOTE COMPANY                          PRODUCTION CORPORATION PAT STATES-216-830-2198
   890 BLAIR MILL ROAD                                         PROOF OF JUNE 23, 1997
    HORSHAM, PA 10044                                           CHROMAVISION MEDICAL
      216-667-3480                                                   H51260bk

- --------------------------------------------       ------------------------------------------------
SALES PERSON-   C. SHARKEY--21G-830-2163           Opr.       JW               NEW
- --------------------------------------------       ------------------------------------------------
/home/joew/inprogress/home11/Chromavision51260        /net/banknote/home51/C3
- ---------------------------------------------      ------------------------------------------------
</TABLE>





<PAGE>

                                                                Exhibit 99.2


                 RIGHTS MAY NOT BE EXERCISED FOR FEWER THAN 20 SHARES 
             OF THE COMMON STOCK OF CHROMAVISION MEDICAL SYSTEMS, INC.



No. R                 RIGHTS TO PURCHASE COMMON STOCK OF

                      CHROMAVISION MEDICAL SYSTEMS, INC.   ___________________
                                                            Number of Rights

            INCORPORATED UNDER THE LAWS OF THE STATE OF DELAWARE,
                              AT $5.00 PER SHARE.
  THESE RIGHTS EXPIRE AT 5:00 P.M., NEW YORK CITY TIME, ON AUGUST 5, 1997.
                                                            CUSIP 17111P 11 2


This Rights Certificate certifies that
















or registered assigns, is the holder of the number of Rights indicated above.
Each Right entitles the holder to purchase one dully paid and non-assessable
share of the common stock, $.01 par value ["Common Stock"] of ChromaVision 
Medical Systems, Inc. (the "Company") during the period beginning July 1, 
1997 and expiring at 5:00 p.m., New York City time, on August 5, 1997 (the 
"Expiration Date"), upon payment of U.S. $5.00 per share of Common Stock (the 
"Exercise Price"). This Rights Certificate is issued under, and the Rights 
represented by this Rights Certificate are subject to, the terms and 
conditions contained in the prospectus dated July 1, 1997 (the "Prospectus"). 
The Prospectus is incorporated herein by reference, and you should read the 
Prospectus for a more complete explanation of the offering and for 
information about the Company.

     To exercise these Rights, you must complete and sign the Election To 
Purchase and Substitute Form W-9 that appear on the back of this Rights 
Certificate. You must send the completed and signed Rights Certificate, or 
Notice of Guaranteed Delivery, and payment in full of the Exercise Price to 
ChaseMellon Shareholder Services, L.L.C. (the "Rights Agent") at the 
addresses on the back of this Rights Certificate. You must pay the exercise 
price in U.S. dollars by cash, check or money order payable to "Safeguard 
Escrow Account." The Rights Agent must receive these documents and full 
payment on or before the Expiration Date. The Rights Agent will not honor any 
exercise of Rights received after the Expiration Date, regardless of when you 
sent your documents to the Rights Agent. For your protection, we suggest that 
you deliver your Rights to the Rights Agent by overnight or express mail 
courier, or, if you mail your Rights, by registered mail.

     You may transfer all or a portion of your Rights by completing and 
signing the Assignment on the back of this Rights Certificate and by 
delivering to the Rights Agent at the addresses on the back of this Rights 
Certificate. The Rights Agent will reissue certificates for the transferred 
Rights in accordance with your instructions and will reissue a certificate to
you for the balance, if any, to the extent it is able to do so before the 
Expiration Date. If you choose to exercise or to transfer less than all of 
your Rights, you should be aware that you may not receive a new Rights 
Certificate in sufficient time to exercise the remaining Rights. The Company, 
the Selling Stockholders named in the Prospectus and the Rights Agent shall 
have no liability to a transferee or transferor of Rights if Rights 
Certificates are not received in time for exercise or sale prior to the 
Expiration Date.

     The holder of these Rights shall not be entitled to any of the rights of 
a stockholder of the Company prior to the issuance of certificates 
representing the Common Stock of the Company purchased upon exercise of these 
Rights. This Rights Certificate shall not be valid unless countersigned by 
the Rights Agent.

     IN WITNESS WHEREOF, ChromaVision Medical Systems, Inc. has caused the 
facsimile signature of its Chief Executive Officer and its Secretary to be 
printed hereon.


Dated:



Countersigned:

     CHASEMELLON SHAREHOLDER SERVICES, L.L.C.
     Rights Agent


By  



                     /s/ Douglas S. Harrington         /s/ Kosyh
                     Chief Executive Officer           Secretary

     Authorized Signature



<PAGE>

The Rights Certificate and the Exercise Price, if any, should be mailed or 
delivered to the Rights Agent as follows:

<TABLE>
<CAPTION>

By Mail                                       By Hand                                    By Overnight Express Mail Courier:
- -------                                       -------                                    ----------------------------------
<S>                                          <C>                                         <C>
ChaseMellon Shareholder Services, L.L.C.      ChaseMellon Shareholder Services, L.L.C.   ChaseMellon Shareholder Services, L.L.C.
Attn: Reorganization Dept.                    Attn: Reorganization Dept.                 Attn: Reorganization Dept.
P.O. Box 3301                                 120 Broadway, 13th Floor                   85 Challenger Rd. Mail Drop-Room
South Hackensack, NJ 07606                    New York, NY 10271                         Ridgefield Park NJ 07660

</TABLE>

- -------------------------------------------------------------------------------
                                  ELECTION TO PURCHASE

The undersigned hereby irrevocably exercises Rights to purchase shares of 
Common Stock of ChromaVision Medical Systems, Inc. as indicated below, on 
the terms and subject to the conditions specified in the Prospectus, receipt 
of which is hereby acknowledged.

Number of shares purchased(1)   _______________(NOTE: 20 share minimum required
                                                        in each account)

Total shares purchased multiplied 
by the $5.00 Exercise Price(2)    $_______________

(1) Each Right entitles the holder to purchase one share of Common Stock.

(2) If the amount enclosed is not sufficient to pay the Exercise Price for all 
shares that are asked to be purchased, or if the number of shares being 
purchased is not specified, the number of shares purchased will be assumed to 
be the maximum number that could be purchased upon payment of such amount. 
Any amount remaining after such division shall be returned to the purchaser.

CASH, CHECK OR MONEY ORDER IN THE AMOUNT OF $____________PAYABLE TO 
"SAFEGUARD ESCROW ACCOUNT" IS ENCLOSED.

Certificates for such shares are to be issued in the name of and delivered 
to________________________________________________________________________
                                   Name
_______________________________________________________________________________
Street Address                       City              State           Zip Code

If such number of shares shall not be all the shares purchasable hereunder, 
a new Rights Certificate for the balance remaining of the shares purchasable 
hereunder will be registered in the name of and delivered to the party named 
above or in the Assignment below:

Daytime Tel. No. of Rights Holder:_____________________(IF JOINTLY OWNED, 
BOTH MUST SIGN)

                              SIGNATURE(S):________________________________

Dated:______________, 1997                  _______________________________
SIGNATURE(S) GUARANTEED:                    NOTE: The above signature(s) must
                                            correspond with the name(s) as
                                            written upon the face of this Rights
                                            Certificate or with the name(s) of 
                                            the assignee appearing in the 
                                            assignment form below in every 
                                            particular without alteration

_______________________________________
IMPORTANT NOTE: A signature guarantee is
required only if the certificate for the
shares being purchased is to be issued in
name(s) other than the name(s) written upon
the face of this certificate or the name(s)
of the assignee appearing in the assignment
form below. See note in the ASSIGNMENT below
regarding eligible guarantors.

- -------------------------------------------------------------------------------

- -------------------------------------------------------------------------------
                              SUBSTITUTE FORM W-9

Department of the Treasury, Internal Revenue Service--Payer's Request for 
Taxpayer Identification Number (TIN) Failure to complete this form may subject 
                 you to 31% federal income tax withholding.

Part 1: PLEASE PROVIDE YOUR TAXPAYER IDENTIFICATION   TIN____________________
NUMBER IN THE SPACE PROVIDED AT RIGHT AND CERTIFY       Social Security or 
BY SIGNING AND DATING BELOW                             Employer Identification
                                                        Number

                                                      Part 2: Check the box if 
                                                              you are awaiting 
                                                              a TIN  / /

Part 3: CERTIFICATION--UNDER PENALTIES OF PERJURY, I CERTIFY THAT (1) the 
number shown on this form is my correct taxpayer Identification number (or a 
TIN has not issued to me but I have mailed or delivered an application to 
receive a TIN or intend to do so in the near future), (2) I am not subject to 
backup withholding either because I have not been notified by the Internal 
Revenue Service (the "IRS") that I am subject to backup withholding as a 
result of a failure to report all interest or dividends or the IRS has 
notified me that I am no longer subject to backup withholding, and (3) all 
other information provided on this form is true, correct and complete.

Dated:_______________________, 1997       SIGNATURE:________________________


You must cross out item (2) above if you have been notified by the IRS that 
you are currently subject to backup withholding because of underreporting 
interest or dividends on your tax return. However, if after being notified by 
the IRS that you were subject to backup withholding, you received another 
notification from the IRS that you are no longer subject to backup 
withholding, do not cross out item (2).
- -------------------------------------------------------------------------------

- -------------------------------------------------------------------------------
                                       ASSIGNMENT

For value received, the undersigned hereby 
sells, assigns and transfers unto                 ______________________________
                                                                Name

PLEASE INSERT SOCIAL SECURITY NUMBER OR OTHER
IDENTIFYING NUMBER OF ASSIGNEE                     /                           /

_______________________________________________________________________________
Street Address                     City              State            Zip Code

Rights to purchase_________________shares of Common Stock of ChromaVision 
Medical Systems, Inc. and hereby

Irrevocably constitutes and appoints_____________________________________ 
Attorney to transfer the said Rights with full power of substitution in the 
premises.

                                          (IF JOINTLY OWNED, BOTH MUST SIGN)

Dated:________________, 1997

                                           SIGNATURE(S):_______________________

SIGNATURE(S) GUARANTEED                    ____________________________________
                                           NOTE: The above signature(s) must 
                                                 correspond with the name(s) 
                                                 as written upon the face of 
                                                 this Rights Certificate.


_________________________________________
The signature(s) must be guaranteed by an
eligible guarantor Institution (banks, 
stockbrokers, savings and loan associations
and credit unions) with membership in the
Medallion STAMP Program.

- -------------------------------------------------------------------------------


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