INTERNATIONAL ISOTOPES INC
NT 10-Q, 2000-11-15
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549


(Check One): [ ]Form 10-K [ ]Form 20-F [ ]Form 11-K [X]Form 10-Q [ ]Form N-SAR

     For Period Ended: September 30, 2000
     [ ] Transition Report on Form 10-K
     [ ] Transition Report on Form 20-F
     [ ] Transition Report on Form 11-K
     [ ] Transition Report on Form 10-Q
     [ ] Transition Report on Form N-SAR

     For the transition Period Ended :
                                       -----------------------------

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  Read Instruction (on back page) before Preparing Form. Please Print or Type.

    Nothing in this form shall be construed to imply that the Commission has
                   verified any information contained herein.
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If the notification relates to a portion of the filing checked above, identify
the item(s) to which the notification relates:

PART I - REGISTRANT INFORMATION

INTERNATIONAL ISOTOPES, INC.
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Full Name of Registrant:

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Former Name if Applicable

1500 SPENCER RD.
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Address of Principal Executive Office (Street and Number)

DENTON, TX 76205
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City, State and Zip Code

PART II - Rules 12b-25(b) AND (c)

If the subject report could not be filed without reasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following should
be completed. (Check box if appropriate)

          (a)  The reasons described in reasonable detail in Part III of this
               form could not be eliminated without unreasonable effort or
               expense;

[X]       (b)  The subject annual report, semi-annual report, transition report
               of Form 10-K, Form 20-F, following the prescribed due date; or
               the subject quarterly report of transition report of Form 10-Q,
               or portion thereof will be filed on or before the fifth calendar
               day following the prescribed due date; and

          (c)  The accountant's statement or other exhibit required by
               Rule12b-25(c) has been attached if applicable.

<PAGE>   2

PART III - NARRATIVE

State below in reasonable detail the reason why the Form 10-K, 11-K, 10-Q,
N-SAR, or the transition report or portion thereof, could not be filed within
the prescribed time period. (Attach Extra Sheets if Needed)

The Company is in the process of completing negotiations for funding and debt
repayment that it believes will resolve certain liquidity issues and will cause
the 10-Q to more accurately reflect the current financial condition of the
Company. These negotiations could not be completed by November 14, 2000 without
unreasonable effort and expense. There can be no assurance, however, that these
transactions will be completed.

PART IV - OTHER INFORMATION

(1)  Name and telephone number or person to contact in regard to this
     notification

             Paul E. Landers                   940                 323-2624
     -------------------------------        ---------         -----------------
               (Name)                      (Area Code)        (Telephone Number)

(2)  Have all other periodic reports required under Section 13 or 15(d) of the
     Securities Exchange Act of 1934 or Section 30 or the Investment Company Act
     of 1940 during the preceding 12 months or for such shorter period that the
     registrant was required to file such report(s) been filled? If answer is
     no, identify report(s). [X] Yes [ ] No

(3)  Is it anticipated that any significant change in results of operations from
     the corresponding period for the last fiscal year will be reflected by the
     earnings statement to be included in the subject report or portion thereof?
     [ ] Yes [X] No

If so, attach an explanation of the anticipated change, both narratively and
quantitatively, and, if appropriate, state the reasons why a reasonable estimate
of the results cannot be made.

                          INTERNATIONAL ISOTOPES, INC.
                  --------------------------------------------
                  (Name of registrant as Specified in Charter)

has caused this notification to be signed on its behalf by the undersigned
hereunto duly authorized


Date: November 14, 2000
     -----------------------------------
By: /s/ David M. Camp
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   David M. Camp, President & CEO

INSTRUCTIONS: The form may be signed by an executive officer of the registrant
or by any other duly authorized representative. The name and title of the person
signing the form shall be typed or printed beneath the signature. If the
statement is signed on behalf of the registrant by an authorized representative
(other than an executive office), evidence of the representative's authority to
sign on behalf of the registrant shall be filed with the form.

                                    ATTENTION
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Intentional misstatements or omissions of fact constitute Federal Criminal
Violations (See 18 U.S.C. 1001).
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