AUTOCYTE INC
8-K, 1999-06-23
LABORATORY ANALYTICAL INSTRUMENTS
Previous: PEGASUS SYSTEMS INC, S-3, 1999-06-23
Next: JUNIPER NETWORKS INC, S-1/A, 1999-06-23



<PAGE>   1
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  ------------

                                    FORM 8-K
                                 CURRENT REPORT

                     PURSUANT TO SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934



                Date of Report (Date of earliest event reported):
                                  JUNE 4, 1999



                                 AUTOCYTE, INC.
             (Exact name of registrant as specified in its charter)



          DELAWARE                         0-21134                56-1995728
(State or other jurisdiction          (Commission File          (IRS Employer
      of incorporation)                    Number)           Identification No.)



             780 PLANTATION DRIVE, BURLINGTON, NORTH CAROLINA 27215
              (Address of principal executive offices and zip code)



               Registrant's telephone number, including area code:
                                 (336) 222-9707




<PAGE>   2


ITEM 5.  OTHER EVENTS

On June 4, 1999, AutoCyte, Inc. ("AutoCyte") and NeoPath, Inc. ("NeoPath")
entered into an Agreement and Plan of Merger (the "Merger Agreement") pursuant
to which a wholly owned subsidiary of AutoCyte will be merged with and into
NeoPath (the "Merger"), with NeoPath becoming a wholly owned subsidiary of
AutoCyte. The form of Merger Agreement is filed as Exhibit 2.1 hereto and is
incorporated herein by reference.

On the effective date of the Merger, each issued and outstanding share of common
stock, $0.01 par value, of NeoPath ("NeoPath Common Stock"), other than shares
held by NeoPath or AutoCyte, will automatically be converted into the right to
receive 0.7903 shares of common stock, $0.01 par value, of AutoCyte ("AutoCyte
Common Stock"). Cash will be paid in lieu of any fractional shares of AutoCyte
Common Stock otherwise issuable in the Merger. Outstanding employee and director
options to purchase shares of NeoPath Common Stock will be converted to AutoCyte
options at the same exchange ratio. The Merger is intended to be a tax-free
reorganization and to be accounted for as a pooling of interests.

Completion of the acquisition is subject to certain conditions, including
approval of AutoCyte's and NeoPath's shareholders and other customary closing
conditions. The Merger Agreement is also subject to termination in certain
circumstances as set forth therein.

On June 18, 1999, AutoCyte announced that the United States Food & Drug
Administration has approved the AutoCyte PREP System(TM) ("PREP") for use in
primary screening for cervical cancer. A copy of AutoCyte's press release dated
June 18, 1999 is filed as Exhibit 99.2 hereto and is incorporated herein by
reference.

ITEM 7.  FINANCIAL STATEMENT, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS.

         (c)      Exhibits.

                  2.1      Agreement and Plan of Merger among AutoCyte, Inc.,
                           Trilogy Acquisition Corporation and NeoPath, Inc.
                           dated as of June 4, 1999. Filed herewith. AutoCyte
                           agrees to furnish supplementally to the Commission
                           upon its request a copy of the omitted exhibits and
                           schedules referenced in the agreement.

                  99.1     Press release dated June 7, 1999. Filed herewith.

                  99.2     Press release dated June 18, 1999. Filed herewith.



                                      -2-

<PAGE>   3


                                   SIGNATURES

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.



Date:  June 23, 1999                     AUTOCYTE, INC.



                                         By:   /s/ William O. Green
                                             ---------------------------------
                                               William O. Green
                                               Vice President, Finance and
                                               Chief Financial Officer


                                      -3-

<PAGE>   4





                                  EXHIBIT INDEX

EXHIBIT
   NO.            DESCRIPTION
- -------           -----------

2.1               Agreement and Plan of Merger among AutoCyte, Inc., Trilogy
                  Acquisition Corporation and NeoPath, Inc. dated as of June 4,
                  1999. Filed herewith. AutoCyte agrees to furnish
                  supplementally to the Commission upon its request a copy of
                  the omitted exhibits and schedules referenced in the
                  agreement.

99.1              Press release dated June 7, 1999.  Filed herewith.

99.2              Press release dated June 18, 1999.  Filed herewith.






                                      -4-

<PAGE>   1

                                                                     EXHIBIT 2.1






                          AGREEMENT AND PLAN OF MERGER
                                     AMONG
                                 AUTOCYTE, INC.
                        TRILOGY ACQUISITION CORPORATION,
                                      AND
                                 NEOPATH, INC.




                            ------------------------

                            DATED AS OF JUNE 4, 1999

                            ------------------------
<PAGE>   2

                               TABLE OF CONTENTS

<TABLE>
<CAPTION>
                                                              PAGE
                                                              ----
<S>                                                           <C>
SECTION 1 -- THE MERGER.....................................    1
     1.1   The Merger.......................................    1
     1.2   Effective Time...................................    1
     1.3   Effects of the Merger............................    2
     1.4   Certificate of Incorporation and Bylaws..........    2
     1.5   Officers and Directors...........................    2
     1.6   Effect on Capital Stock..........................    2
     1.7   Closing of NeoPath Transfer Books................    3
     1.8   NeoPath Dissenting Shares........................    3
     1.9   Issuance of AutoCyte Certificates................    4
     1.10  Lost, Stolen or Destroyed Certificates...........    4
     1.11  No Further Ownership Rights in NeoPath Common
      Stock.................................................    4
     1.12  Tax and Accounting Consequences..................    5
SECTION 2 -- REPRESENTATIONS AND WARRANTIES OF NEOPATH......    5
     2.1   Organization and Qualification...................    5
     2.2   Capitalization...................................    5
     2.3   Authority to Execute and Perform Agreements......    6
     2.4   Subsidiaries and Other Affiliates................    6
     2.5   Charter and Bylaws; Books and Records............    6
     2.6   SEC Reports......................................    6
     2.7   Financial Statements.............................    6
     2.8   Absence of Undisclosed Liabilities...............    7
     2.9   No Material Adverse Change.......................    7
     2.10  Tax Matters......................................    8
     2.11  Compliance with Laws.............................    9
     2.12  Consents; No Breach..............................    9
     2.13  Actions and Proceedings..........................   10
     2.14  Contracts and Other Agreements...................   10
     2.15  Real Property; Leases............................   11
     2.16  Tangible Property................................   11
     2.17  Intellectual Property............................   11
     2.18  Title to Assets; Liens...........................   12
     2.19  Employee Benefit Plans...........................   12
     2.20  Employee Relations...............................   13
     2.21  Relationships with Affiliates....................   13
     2.22  Insurance........................................   13
     2.23  Brokerage........................................   13
     2.24  Hazardous Materials..............................   13
     2.25  Registration Statement; Proxy Statement..........   14
     2.26  Opinion of Financial Adviser.....................   14
     2.27  Accounting Matters...............................   14
     2.28  Full Disclosure..................................   14
SECTION 3 -- REPRESENTATIONS AND WARRANTIES OF AUTOCYTE.....   14
     3.1   Organization and Qualification...................   15
     3.2   Capitalization...................................   15
     3.3   Authority to Execute and Perform Agreements......   15
     3.4   Subsidiaries and Other Affiliates................   16
     3.5   Charter and By-laws; Books and Records...........   16
     3.6   SEC Reports......................................   16
</TABLE>

                                        I
<PAGE>   3
                               TABLE OF CONTENTS
                                  (CONTINUED)

<TABLE>
<CAPTION>
                                                              PAGE
                                                              ----
<S>                                                           <C>
     3.7   Financial Statements.............................   16
     3.8   Absence of Undisclosed Liabilities...............   16
     3.9   No Material Adverse Change.......................   17
     3.10  Tax Matters......................................   17
     3.11  Compliance with Laws.............................   18
     3.12  Consents; No Breach..............................   19
     3.13  Actions and Proceedings..........................   19
     3.14  Contracts and Other Agreements...................   19
     3.15  Real Property; Leases............................   21
     3.16  Tangible Property................................   21
     3.17  Intellectual Property............................   21
     3.18  Title to Assets; Liens...........................   21
     3.19  Employee Benefit Plans...........................   22
     3.20  Employee Relations...............................   22
     3.21  Relationships with Affiliates....................   23
     3.22  Insurance........................................   23
     3.23  Brokerage........................................   23
     3.24  Hazardous Materials..............................   23
     3.25  Registration Statement; Proxy Statement..........   23
     3.26  Opinion of Financial Adviser.....................   24
     3.27  Accounting Matters...............................   24
     3.28  Full Disclosure..................................   24
SECTION 4 -- COVENANTS AND AGREEMENTS.......................   24
     4.1   Conduct of NeoPath Business......................   24
     4.2   Conduct of AutoCyte Business.....................   25
     4.3   Nasdaq Listing...................................   26
     4.4   Corporate Examinations and Investigations........   26
     4.5   Agreement not to Entertain Other Offers..........   27
     4.6   Authorization from Others........................   27
     4.7   Consummation of Agreement........................   27
     4.8   Further Assurances...............................   28
     4.9   Joint Proxy Statement/Prospectus; Registration
      Statement.............................................   28
     4.10  NeoPath Stockholder Meeting......................   28
     4.11  AutoCyte Stockholder Meeting.....................   29
     4.12  Public Announcements and Confidentiality.........   29
     4.13  NeoPath Affiliate Agreements.....................   29
     4.14  AutoCyte Affiliate Agreements....................   29
     4.15  AutoCyte SEC Filings.............................   29
     4.16  NeoPath SEC Filings..............................   30
     4.17  Stock Options; Employee Stock Purchase Plan......   30
     4.18  AutoCyte Form S-8................................   30
     4.19  FIRPTA...........................................   30
     4.20  Notification of Certain Matters..................   31
     4.21  Tax-Free Reorganization..........................   31
     4.22  Indemnification..................................   31
     4.23  Pooling of Interests.............................   31
     4.24  Letters of AutoCyte's and NeoPath's
      Accountants...........................................   31
     4.25  Employee Benefit Plans; Existing Agreement.......   32
</TABLE>

                                       II
<PAGE>   4
                               TABLE OF CONTENTS
                                  (CONTINUED)

<TABLE>
<CAPTION>
                                                              PAGE
                                                              ----
<S>                                                           <C>
SECTION 5 -- CONDITIONS PRECEDENT TO THE OBLIGATIONS OF EACH
             PARTY TO CONSUMMATE THE MERGER.................   32
     5.1   Stockholder Approvals............................   32
     5.2   Government Approvals.............................   32
     5.3   Absence of Restraints............................   32
     5.4   Nasdaq Listing...................................   32
     5.5   Effectiveness of Registration Statement..........   33
     5.6   Tax Opinions.....................................   33
     5.7   Pooling Letters..................................   33
SECTION 6 -- CONDITIONS PRECEDENT TO THE OBLIGATION OF
             AUTOCYTE TO CONSUMMATE THE MERGER..............   33
     6.1   Representations, Warranties and Covenants........   33
     6.2   NeoPath Affiliate Agreements.....................   33
     6.3   Voting Agreement.................................   33
     6.4   Opinion of Counsel to NeoPath....................   33
     6.5   Merger Documents.................................   33
     6.6   Consents.........................................   33
     6.7   Dissenting Shares................................   33
     6.8   Certificates.....................................   33
SECTION 7 -- CONDITIONS PRECEDENT TO THE OBLIGATION OF
             NEOPATH TO CONSUMMATE THE MERGER...............   34
     7.1   Representations, Warranties and Covenants........   34
     7.2   AutoCyte Affiliate Agreements....................   34
     7.3   Voting Agreement.................................   34
     7.4   Consents.........................................   34
     7.5   Opinion of Counsel to AutoCyte...................   34
     7.6   Certificates.....................................   34
SECTION 8 -- TERMINATION....................................   34
     8.1   Termination......................................   34
     8.2   Notice of Termination; Effect of Termination.....   35
     8.3   Fees and Expenses................................   36
SECTION 9 -- MISCELLANEOUS..................................   38
     9.1   Notices..........................................   38
     9.2   Amendment........................................   38
     9.3   Waiver...........................................   38
     9.4   Entire Agreement.................................   39
     9.5   Governing Law....................................   39
     9.6   Binding Effect; No Assignment....................   39
     9.7   Variations in Pronouns...........................   39
     9.8   Counterparts.....................................   39
     9.9   Exhibits and Disclosure Schedules................   39
</TABLE>

                                       III
<PAGE>   5

                        INDEX OF SCHEDULES AND EXHIBITS

Schedule 1     Officers of AutoCyte Immediately after the Effective Time.
Schedule 2     Board of Directors of AutoCyte Immediately After the Effective
               Time
AutoCyte Disclosure Schedule
AutoCyte Disclosure Schedule
Exhibit A --  Form of NeoPath Voting Agreement
Exhibit B --  Form of AutoCyte Voting Agreement
Exhibit C --  Form of NeoPath Affiliate Agreement
Exhibit D --  Form of AutoCyte Affiliate Agreement
Exhibit E --  Form of Opinion of Perkins Coie LLP
Exhibit F --  Form of Opinion of Palmer & Dodge LLP




                                       IV
<PAGE>   6

                          AGREEMENT AND PLAN OF MERGER

     THIS AGREEMENT AND PLAN OF MERGER dated as of June 4, 1999 (this
"Agreement") is among AutoCyte, Inc. ("AutoCyte"), a Delaware corporation,
Trilogy Acquisition Corporation, a Delaware corporation and wholly-owned
subsidiary of AutoCyte ("Merger Sub") and NeoPath, Inc. ("NeoPath"), a
Washington corporation. The parties wish to effect the combination of NeoPath
and AutoCyte through a merger of Merger Sub into NeoPath on the terms and
conditions hereof. This Agreement is intended to be a "plan of reorganization"
within the meaning of sec.368(a) of the Internal Revenue Code of 1986, as
amended (the "Code").

                                    RECITALS

     A. Upon the terms and subject to the conditions of this Agreement and in
accordance with the Delaware General Corporation Law (the "DGCL") and the
Washington Business Corporation Act (the "WBCA"), AutoCyte, Merger Sub and
NeoPath will enter into a business combination transaction pursuant to which
Merger Sub will merge with and into NeoPath (the "Merger").

     B. The Board of Directors of AutoCyte (i) has determined that the Merger is
consistent with and in furtherance of the long-term business strategy of
AutoCyte and fair to, and in the best interests of, AutoCyte and its
stockholders, (ii) has approved this Agreement, the Merger and the other
transactions contemplated by this Agreement, and (iii) has recommended approval
of this Agreement by the stockholders of AutoCyte.

     C. The Board of Directors of NeoPath (i) has determined that the merger is
consistent with and in furtherance of the long-term business strategy of NeoPath
and fair to, and in the best interest of, NeoPath and its stockholders, (ii) has
approved this Agreement, the Merger and the other transactions contemplated by
this Agreement and (iii) has recommended the approval of this Agreement by the
stockholders of NeoPath.

     D. Concurrently with the execution of this Agreement, and as a condition
and inducement to AutoCyte's willingness to enter into this Agreement, certain
affiliates of NeoPath shall each enter into a Voting Agreement in the form
attached hereto as Exhibit A (the "NeoPath Voting Agreements").

     E. Concurrently with the execution of this Agreement, and as a condition
and inducement to NeoPath's willingness to enter into this Agreement, certain
affiliates of AutoCyte shall each enter into a Voting Agreement in the form
attached hereto as Exhibit B (the "AutoCyte Voting Agreements").

     F. AutoCyte, Merger Sub and NeoPath desire to make certain representations
and warranties and other agreements in connection with the Merger.

     G. The parties intend, by executing this Agreement, to adopt a plan of
reorganization within the meaning on Section 368 of the Code.

     Accordingly, in consideration of the mutual representations, warranties and
covenants contained herein, the parties hereto agree as follows:

                            SECTION 1 -- THE MERGER

     1.1  The Merger.  Upon the terms and subject to the conditions hereof, and
in accordance with the DGCL and the WBCA, Merger Sub shall be merged with and
into NeoPath. The Merger shall occur at the Effective Time (as defined herein).
Following the Merger, NeoPath shall continue as the surviving corporation (the
"Surviving Corporation") and the separate corporate existence of Merger Sub
shall cease.

     1.2  Effective Time.  As soon as practicable after satisfaction or waiver
of all conditions to the Merger, the parties shall cause merger documents to be
filed in accordance with Section 23B.11.070 of the WBCA and a Certificate of
Merger to be filed in accordance with Section 252 of the DGCL (the Washington
merger documents and the Certificate of Merger are referred to collectively
herein as the "Merger Documents") and shall take all such further actions as may
be required by law to make the Merger effective. The Merger shall be effective
at such time as the Merger Documents are filed, as appropriate, with the
Secretary of State of the
<PAGE>   7

State of Washington in accordance with the WBCA and with the Secretary of State
of the State of Delaware in accordance with the DGCL or at such later time as is
specified in such documents (the "Effective Time"). Immediately prior to the
filing of the Merger Documents, a closing (the "Closing") will be held at the
offices of Palmer & Dodge LLP, One Beacon Street, Boston, Massachusetts (or such
other place as the parties may agree) for the purpose of confirming satisfaction
or waiver of all conditions to the Merger. Subject to satisfaction or waiver of
each of the conditions specified in Sections 5, 6 and 7 hereof, the Closing
shall take place within three business days after the last to occur of:

          (a) the day the Merger is approved by the stockholders of NeoPath
     pursuant to Section 4.10; or

          (b) the day the issuance of the AutoCyte Common Stock (as defined
     below) is approved by the stockholders of AutoCyte pursuant to Section
     4.11;

or on such other date as the parties may agree, but not later than November 30,
1999. The date on which the Closing occurs is referred to herein as the "Closing
Date".

     1.3  Effects of the Merger.  The Merger shall have the effects set forth in
Section 23B.11.060 of the WBCA and Sections 259, 260 and 261 of the DGCL.

     1.4  Certificate of Incorporation and Bylaws.  The Articles of
Incorporation (the "Articles of Incorporation") and Bylaws (the "Bylaws") of
NeoPath, in each case as in effect immediately prior to the Effective Time,
shall be the Articles of Incorporation and Bylaws of the Surviving Corporation
immediately after the Effective Time, until duly amended in accordance with
applicable law and such Articles of Incorporation.

     1.5  Officers and Directors.

     (a) Officers.  Immediately prior to the Effective Time, the persons listed
on Schedule 1 attached hereto shall be the officers of AutoCyte and such persons
shall be the initial officers of the Surviving Corporation, each person to hold
the office set forth opposite each such person's name in accordance with the
Certificate of Incorporation and Bylaws of AutoCyte and the Articles of
Incorporation and Bylaws of the Surviving Corporation, respectively.

     (b) Directors.  Prior to the Effective Time, AutoCyte shall (i) increase
the number of the members of the Board of Directors of AutoCyte to seven (7) and
(ii) take such action as may be necessary to ensure that the Board of Directors
of AutoCyte, immediately after the Effective Time, is comprised of the persons
listed on Schedule 2 attached hereto. The initial directors of the Surviving
Corporation shall be the persons listed on Schedule 2.

     1.6  Effect on Capital Stock.

     (a) Conversion of NeoPath Common Stock.  At the Effective Time, by virtue
of the Merger and without any action on the part of AutoCyte or NeoPath:

          (i) each share of Common Stock, $.01 par value, of NeoPath (the
     "NeoPath Common Stock") issued and outstanding immediately prior to the
     Effective Time (other than any shares of NeoPath Common Stock to be
     cancelled pursuant to Section 1.6(a)(iii) and other than Dissenting Shares
     (as defined in Section 1.8)) will be cancelled and extinguished and
     automatically be converted (subject to Section 1.6(b) and (c)) into the
     right to receive 0.7903 (the "Exchange Ratio") shares of Common Stock, $.01
     par value, of AutoCyte (the "AutoCyte Common Stock") upon surrender of the
     certificate representing such share of NeoPath Common Stock in the manner
     provided in Section 1.9 (or in the case of a lost, stolen or destroyed
     certificate, upon delivery of an affidavit (and bond, if required) in the
     manner provided in Section 1.10);

          (ii) subject to and in accordance with Section 4.17, all options and
     warrants to purchase NeoPath Stock outstanding immediately prior to the
     Effective Time, shall be exchanged for options of AutoCyte exercisable for
     that number of shares of AutoCyte Common Stock which such option or warrant
     holder would have been entitled to receive if the underlying NeoPath Common
     Stock had converted in the Merger, at an exercise price per share equal to
     the aggregate exercise price of the NeoPath option or warrant exchanged
     divided by the number of shares of AutoCyte Common Stock subject to the new



                                        2
<PAGE>   8

     option or warrant, and otherwise having the same terms and conditions as
     the NeoPath option or warrant and otherwise;

          (iii) all shares of NeoPath Common Stock held at the Effective Time by
     NeoPath as treasury stock, by AutoCyte or by a subsidiary of either NeoPath
     or AutoCyte shall be canceled and no payment shall be made with respect
     thereto; and

          (iv) all Dissenting Shares shall be dealt with in accordance with
     Section 1.8;

     (b) Adjustments to Exchange Ratio.  The Exchange Ratio shall be adjusted to
reflect fully the effect of any stock split, reverse stock split, stock dividend
(including any dividend or distribution of securities convertible into AutoCyte
Common Stock or NeoPath Common Stock), recapitalization or other like change
without receipt of consideration with respect to AutoCyte Common Stock or
NeoPath Common Stock occurring on or after the date hereof and prior to the
Effective Time. In addition, during the period from the date of this Agreement
and continuing until the earlier of the termination of the Agreement or the
Effective Time, AutoCyte shall not, without the prior written consent of
NeoPath, declare or pay any dividend or distribution on the AutoCyte Common
Stock (other than ordinary cash dividends) unless prior thereto either (i)
AutoCyte shall have provided that holders of NeoPath Common Stock, upon the
Effective Time, shall receive such dividend or distribution to the same extent
they would have if their shares of NeoPath Common Stock had been converted to
AutoCyte Common Stock immediately prior to the record date of any such dividend
or distribution or (ii) AutoCyte and NeoPath shall mutually have agreed upon an
adjustment of the Exchange Ratio to fully reflect the effect of any such
dividend or distribution.

     (c) Fractional Shares.  No fraction of a share of AutoCyte Common Stock
will be issued by virtue of the Merger, but in lieu thereof each holder of
shares of NeoPath Common Stock who would otherwise be entitled to a fraction of
a share of AutoCyte Common Stock (after aggregating all fractional shares of
AutoCyte Common Stock to be received by such holder) shall receive from AutoCyte
an amount of cash (rounded to the nearest whole cent) equal to the product of
(i) such fraction, multiplied by (ii) the average closing price of a share of
AutoCyte Common Stock for the ten most recent days that AutoCyte Common Stock
has traded ending on the trading day immediately prior to the Effective Time, as
reported on the Nasdaq National Market.

     1.7  Closing of NeoPath Transfer Books.  At the Effective Time, the stock
transfer books of NeoPath shall be closed and no transfer of NeoPath Common
Stock shall thereafter be made. If, after the Effective Time, certificates
representing shares of NeoPath Common Stock are presented to the Exchange Agent
(as defined in Section 1.9), they shall be canceled and exchanged for
certificates representing AutoCyte Common Stock as provided in this Section 1.

     1.8  NeoPath Dissenting Shares.  Shares of NeoPath Common Stock held by a
stockholder who has properly exercised appraisal rights with respect thereto in
accordance with Section 23B.13.020 of the WBCA are referred to herein as
"Dissenting Shares". Shares of NeoPath Common Stock that constitute Dissenting
Shares shall not be converted into shares of AutoCyte Common Stock and shares of
AutoCyte Common Stock shall not be issued pursuant to Section 1.6(a) in exchange
therefor. From and after the Effective Time, a stockholder who has properly
exercised such appraisal rights shall no longer retain any rights of a
stockholder of NeoPath or the Surviving Corporation, except those provided under
the WBCA. NeoPath shall give AutoCyte (i) prompt notice of any written notices
and demands under Section 23B.13.210 of the WBCA with respect to any shares of
capital stock of NeoPath, any withdrawal of any such demands and any other
instruments served pursuant to the WBCA and (ii) the right to participate in all
negotiations and proceedings with respect to any demands under Section
23B.13.020 of the WBCA with respect to any shares of capital stock of NeoPath.
NeoPath shall cooperate with AutoCyte concerning, and shall not, except with the
prior written consent of AutoCyte, voluntarily make any payment with respect to,
or offer to settle or settle, any such demands.



                                        3
<PAGE>   9

     1.9  Issuance of AutoCyte Certificates.

     (a) Exchange Agent.  Prior to the Effective Time, AutoCyte shall authorize
one or more persons to act as Exchange Agent hereunder (the "Exchange Agent")
and shall deposit with or for the account of the Exchange Agent certificates
representing the number of shares of AutoCyte Common Stock issuable pursuant to
Section 1.6 and cash in lieu of fractional shares of AutoCyte Common Stock.

     (b) Exchange Procedures.  As soon as practicable after the Effective Time,
(i) NeoPath shall deliver to AutoCyte a list of all record holders of NeoPath
Common Stock immediately prior to the Effective Time (the "Record Holders"),
setting forth each stockholder's name, address and number of shares of NeoPath
Common Stock held prior to the Effective Time and such other information as may
be reasonably requested by the Exchange Agent, certified by the Chief Executive
Officer of NeoPath (the "Stockholder List") and (ii) the Exchange Agent shall be
instructed to mail to each Record Holder a form of letter of transmittal which
shall specify instructions for use in effecting the surrender of NeoPath Common
Stock certificates in exchange for AutoCyte Common Stock certificates and cash
in lieu of fractional shares. Upon the Exchange Agent's receipt of the letter of
transmittal and any certificate held by a stockholder, each stockholder shall be
entitled to receive a certificate representing that number of whole shares of
AutoCyte Common Stock into which the shares of NeoPath Common Stock as set forth
on the Stockholder List shall have been converted pursuant to the provisions of
this Agreement. The shares of NeoPath Common Stock outstanding immediately prior
to the Effective Time (and any certificates representing such shares) shall be
deemed canceled as of the Effective Time. AutoCyte Common Stock into which
NeoPath Common Stock shall be converted in the Merger shall be deemed to have
been issued at the Effective Time. If any AutoCyte Common Stock certificates are
to be issued in a name other than that in which the NeoPath Common Stock was
registered immediately prior to the Effective Time, it shall be a condition of
such issuance that the person requesting such issuance shall deliver to the
Exchange Agent all documents necessary to evidence and effect such transfer and
shall pay to the Exchange Agent any transfer or other taxes required by reason
of the issuance of certificates for such shares of AutoCyte Common Stock in a
name other than that of the registered holder of the certificate or surrendered
or establish to the satisfaction of the Exchange Agent that such tax has been
paid or is not applicable. Neither AutoCyte nor NeoPath shall be liable to any
stockholder for shares of stock or any cash in lieu of fractional interests
delivered to a public official pursuant to applicable escheat or abandoned
property laws.

     (c) Distributions of NeoPath Common Stock.  No dividends or other
distributions declared or made after the date of this Agreement with respect to
AutoCyte Common Stock with a record date after the Effective Time will be paid
to the holder of any unsurrendered certificate of NeoPath Common Stock with
respect to the shares of AutoCyte Common Stock represented thereby until the
holder of record of such certificate shall surrender such certificate. Subject
to applicable law, following surrender of any such certificate, there shall be
paid to the record holder thereof certificates representing whole shares of
AutoCyte Common Stock issued in exchange therefor, without interest, along with
the amount of dividends or other distributions with a record date after the
Effective Time payable with respect to such whole shares of AutoCyte Common
Stock and cash in lieu of any fractional shares in accordance with Section
1.6(c).

     1.10  Lost, Stolen or Destroyed Certificates.  In the event any NeoPath
Common Stock certificates shall have been lost, stolen or destroyed, the
Exchange Agent shall issue in exchange for such lost, stolen or destroyed
certificates, upon the making of an affidavit of that fact by the holder
thereof, such shares of AutoCyte Common Stock, cash for fractional shares, if
any, as may be required pursuant to Section 1.6(c) and any dividends or
distributions payable pursuant to Section 1.9(c); provided, however, that
AutoCyte may, in its discretion and as a condition precedent to the issuance
thereof, require the owner of such lost, stolen or destroyed certificates to
deliver a bond in such sum as it may reasonably direct as indemnity against any
claim that may be made against AutoCyte or the Exchange Agent with respect to
the certificates alleged to have been lost, stolen or destroyed.

     1.11  No Further Ownership Rights in NeoPath Common Stock.  All shares of
AutoCyte Common Stock issued upon the surrender for exchange of shares of
NeoPath Common Stock in accordance with the terms hereof (including any cash
paid in respect thereof pursuant to Sections 1.6(c) and 1.9) shall be deemed



                                        4
<PAGE>   10

to have been issued in full satisfaction of all rights pertaining to such shares
of NeoPath Common Stock, and there shall be no further registration of transfers
on the records of AutoCyte of shares of NeoPath Common Stock that were
outstanding immediately prior to the Effective Time.

     1.12  Tax and Accounting Consequences.  It is intended by the parties
hereto that the Merger shall constitute a reorganization within the meaning of
Section 368 of the Code. It is also intended by the parties hereto that the
Merger shall be treated as a "pooling of interests" for accounting purposes.

             SECTION 2 -- REPRESENTATIONS AND WARRANTIES OF NEOPATH

     Except as set forth on the disclosure schedule (the "NeoPath Disclosure
Schedule") delivered to AutoCyte on the date hereof (regardless of whether the
NeoPath Disclosure Schedule is referenced in any particular subsection of this
Section 2), the subsection numbers of which are numbered to correspond to the
subsection numbers of this Agreement to which they refer, NeoPath represents and
warrants to AutoCyte as set forth below:

     2.1  Organization and Qualification.  NeoPath is a corporation duly
organized, validly existing and in good standing under the laws of the state or
other jurisdiction of its incorporation and has full corporate power and
authority to own, lease and operate its assets, properties and business and to
carry on its business as now being and as heretofore conducted. NeoPath is
qualified or is otherwise authorized to transact business as a foreign
corporation in each jurisdiction (in the United States and outside of the United
States) in which the failure to so qualify would have a NeoPath Material Adverse
Effect, all of which jurisdictions are identified in Section 2.1 of the NeoPath
Disclosure Schedule. A "Material Adverse Effect" on NeoPath or AutoCyte, as the
case may be, means (unless otherwise specified) any condition or event that (i)
materially adversely affects the assets, business, financial condition,
operations or prospects of such party, other than any condition or event (A)
relating to the economy in general, (B) relating to the industries in which such
party operates in general, (C) arising out of or resulting from actions
contemplated by the parties in connection with, or which is attributable to, the
announcement of this Agreement and the transactions contemplated hereby
(including loss of personnel, customers or suppliers or the delay or
cancellation of orders for products) or (D) litigation brought or threatened
against such party or any member of their respective Boards of Directors in
respect of this Agreement, (ii) materially impairs the ability of such party to
perform its obligations under this Agreement or (iii) prevents or materially
delays the consummation of the transactions contemplated under this Agreement.

     2.2  Capitalization.

     (a) Outstanding Capital Stock.  NeoPath's authorized capital stock consists
of 40,000,000 shares of Common Stock, $.01 par value per share, of which
17,414,230 shares are issued and outstanding as of June 4, 1999, and 10,000,000
shares of Preferred Stock, $.01 par value per share, of which no shares are
issued and outstanding. Except as disclosed in NeoPath's proxy statement for its
annual meeting of stockholders held on May 20, 1999, NeoPath is not aware of any
record or beneficial holder of more than five percent (5%) of the outstanding
shares of NeoPath Common Stock. The outstanding shares of NeoPath Common Stock
are duly authorized, validly issued, fully paid and nonassessable and have been
issued in compliance with all charter documents of NeoPath and all applicable
federal and state laws. Except as set forth in this Section 2.2(a), no other
capital stock of NeoPath is authorized or outstanding.

     (b) Options or Other Rights.  Section 2.2(b) of the NeoPath Disclosure
Schedule lists each outstanding option to acquire shares of NeoPath Common Stock
under the NeoPath, Inc. 1989 Stock Option Plan (Amended and Restated on February
26, 1998), the NeoPath, Inc. Stock Option Plan for Nonemployee Directors
(Amended and Restated on February 27, 1997 or the NeoPath, Inc. 1999 Stock
Incentive Compensation Plan (together, the "NeoPath Stock Option Plans") as of
the date hereof, the name of the holder of such option, the number of shares
subject to such option, the exercise price of such option, the number of shares
as to which such option will have vested at such date and whether the
exercisability of such option will be accelerated in any way by the transactions
contemplated by this Agreement or for any other reason, and indicates the extent
of acceleration, if any. Except as set forth in the NeoPath Disclosure Schedule,



                                        5
<PAGE>   11

(i) no subscription, warrant, option, preemptive right, convertible security or
other right (contingent or otherwise) to purchase or acquire any shares of
capital stock or other security of NeoPath issued by NeoPath is authorized or
outstanding, (ii) there is no commitment or offer by NeoPath to issue or provide
any such subscription, warrant, option, preemptive right, convertible security
or other right or to issue or distribute to holders of any shares of its capital
stock any evidences of indebtedness or assets of NeoPath, (iii) NeoPath has no
obligation (contingent or otherwise) to purchase, redeem or otherwise acquire
any shares of its capital stock or any interest therein or to pay any dividend
or make any other distribution in respect thereof, (iv) there are no
restrictions on the transfer of NeoPath's capital stock other than those arising
from securities laws, and (v) there are no voting trusts, proxies or other
agreements, instruments or understandings with respect to outstanding shares of
NeoPath's capital stock to which NeoPath is a party.

     2.3  Authority to Execute and Perform Agreements.  NeoPath has the
requisite corporate power and authority to execute and deliver this Agreement
and each agreement, document and instrument contemplated by this Agreement to
which it is a party and, subject to the requirement to obtain stockholder
approval under the WBCA, to consummate the transactions contemplated hereby and
thereby and to perform fully its respective obligations hereunder and
thereunder. The execution, delivery and performance of this Agreement and each
such other agreement, document and instrument to which it is a party and the
consummation of the transactions contemplated hereby and thereby have been duly
authorized by all necessary corporate action on the part of NeoPath, subject, in
the case of the Merger, to the requirement to obtain stockholder approval under
the WBCA. This Agreement and each agreement, document and instrument executed
and delivered by NeoPath pursuant to this Agreement constitutes, or when
executed and delivered will constitute, valid and binding obligations of
NeoPath, enforceable in accordance with their terms, subject to bankruptcy,
insolvency, fraudulent transfer, reorganization, moratorium and similar laws of
general applicability relating to or affecting creditors' rights and to general
principles of equity.

     2.4  Subsidiaries and Other Affiliates.  NeoPath does not have any
subsidiary or directly or indirectly own or have any investment in any of the
capital stock of, or any other interest in, any other person or entity

     2.5  Charter and Bylaws; Books and Records.  NeoPath has heretofore
delivered or made available to AutoCyte true and complete copies of the Articles
of Incorporation (certified by the Secretary of State or comparable authority of
its jurisdiction of incorporation) and Bylaws as in effect on the date hereof,
and corporate minute books. NeoPath is not in default in the performance,
observation or fulfillment of either its charter or Bylaws. The minute books of
NeoPath contain true and complete records of all meetings and consents in lieu
of meetings of the Board of Directors and of the stockholders prior to the date
hereof, and accurately reflect all transactions referred to in such minutes and
consents in lieu of meetings.

     2.6  SEC Reports.  NeoPath has previously delivered to AutoCyte its (i)
Annual Report on Form 10-K for the years ended December 31, 1998 (the "NeoPath
10-K") and 1997, as filed with the Securities and Exchange Commission (the
"SEC"), (ii) the proxy statement relating to NeoPath's annual meeting of
stockholders held on May 20, 1999 and (iii) all other reports filed by NeoPath
with the SEC under the Securities Exchange Act of 1934, as amended (the
"Exchange Act"), since January 1, 1998 (the "NeoPath SEC Documents"). As of
their respective dates, the NeoPath SEC Documents complied as to form in all
material respects with applicable SEC requirements and, except to the extent
that information contained in any NeoPath SEC Document has been revised and
superseded by a later filed NeoPath SEC Document, did not contain any untrue
statement of a material fact or omit to state a material fact required to be
stated therein or necessary to make the statements therein, in light of the
circumstances under which they were made, not misleading. NeoPath has timely
filed with the SEC all reports required to be filed under Sections 13, 14 or
15(d) of the Exchange Act since January 1, 1998.

     2.7  Financial Statements.  The financial statements contained in the
NeoPath 10-K and in NeoPath's quarterly report on Form 10-Q for the quarter
ended March 31, 1999 (the "NeoPath 10-Q") have been prepared from, and are in
accordance with, the books and records of NeoPath and fairly present the
financial condition, results of operations and cash flows of NeoPath as of the
dates and for the periods presented therein, all in accordance with generally
accepted accounting principles applied on a consistent basis, except as
otherwise indicated therein and subject (in the case of the unaudited financial
statements included in the


                                        6

<PAGE>   12

NeoPath 10-Q) to normal period-end and audit adjustments and footnote
disclosures, which in the aggregate are not material.

     2.8  Absence of Undisclosed Liabilities.  Except as set forth in the
NeoPath Disclosure Schedule, at December 31, 1998, NeoPath had no material
liabilities of any nature, whether accrued, absolute, contingent or otherwise
(including without limitation, liabilities as guarantor or otherwise with
respect to obligations of others or liabilities for taxes due or then accrued or
to become due), required to be reflected or disclosed in the balance sheet dated
December 31, 1998 (or the notes thereto) included in the NeoPath 10-K (the
"NeoPath Balance Sheet") that were not adequately reflected or reserved against
on such balance sheet. Except as set forth in the NeoPath Disclosure Schedule,
NeoPath has no such liabilities, except as and to the extent (i) adequately
reflected and reserved against in the NeoPath Balance Sheet, (ii) adequately
reflected and reserved against in the NeoPath unaudited balance sheet dated
March 31, 1999 included in the NeoPath 10-Q (the "NeoPath Interim Balance
Sheet"), or (iii) incurred since March 31, 1999 in the ordinary course of
business.

     2.9  No Material Adverse Change.  Except as set forth in the NeoPath
Disclosure Schedule, since March 31, 1999, there has not been:

          (a) any event or occurrence that could reasonably be expected to have
     a NeoPath Material Adverse Effect;

          (b) any material change in the method of operating the business of
     NeoPath, in the manner of keeping the books, accounts or records of, or in
     any accounting method or practice of NeoPath;

          (c) any sale, lease, mortgage, pledge, encumber, abandonment or
     disposition of, or agreement to sell, lease, mortgage, pledge, encumber,
     abandon or dispose of, any material assets or properties of NeoPath, other
     than in the usual and ordinary course of business;

          (d) any material transaction, commitment, contract or agreement
     entered into by NeoPath, or any relinquishment or abandonment by NeoPath of
     any material contract or right, or any modification, waiver, amendment,
     release, recision, or termination of any material term, condition or
     provision of any contract to which NeoPath is a party and is or should be
     set forth on the NeoPath Disclosure Schedule in accordance with Section
     2.14 (other than any satisfaction by performance in accordance with the
     terms thereof), other than in the usual and ordinary course of business;

          (e) any adverse relationships or conditions with employees, suppliers,
     lenders, customers or governmental agencies that could reasonably be
     anticipated to have a NeoPath Material Adverse Effect;

          (f) any acquisition by NeoPath (other than property or interests
     therein acquired in the ordinary course of its business) of all or any part
     of the assets, properties, capital stock or business of any other person or
     entity;

          (g) any redemption or other acquisition by NeoPath of any of its
     capital stock or any declaration, setting aside or payment of any dividend
     or distribution of any kind with respect to shares of its capital stock;

          (h) any loan or advance by NeoPath to any stockholder, officer,
     director or consultant, or any other loan or advance other than in the
     ordinary course of business;

          (i) any cancellation, nonrenewal, material reduction in limits or
     coverage or material premium increase for all insurance policies maintained
     by NeoPath;

          (j) except as set forth in the NeoPath Disclosure Schedule, any new
     employment or consulting agreement, any increase in compensation, bonus or
     other benefits payable or to become payable by NeoPath to any director,
     officer or employee, other than regularly scheduled increases consistent
     with past practice in the ordinary course of business, or any new grant of
     severance or termination rights, or increase in rights or benefits payable
     under existing severance or termination policies or agreements, to any
     director, officer or employee of NeoPath; or


                                        7
<PAGE>   13

          (k) commitment, understanding or agreement of NeoPath or any officer
     or employee thereof to do any of the things described in the preceding
     clauses (a) through (i) (other than this Agreement).

     2.10  Tax Matters.

     (a) Definition of Taxes.  For the purposes of this Agreement, "Tax" or,
collectively, "Taxes", means any and all federal, state, local and foreign
taxes, assessments and other governmental charges, duties, impositions and
liabilities in the nature of a tax including taxes based upon or measured by
gross receipts, income, profits, sales, use and occupation, and value added, ad
valorem, transfer, franchise, withholding, payroll, recapture, employment,
excise and property taxes, together with all interest, penalties and additions
imposed with respect to such amounts and any obligations under any agreements or
arrangements with any other person with respect to such amounts and including
any liability for taxes of a predecessor entity.

     (b) Tax Returns and Audits.  Except as set forth in the NeoPath Disclosure
Schedule:

          (i) NeoPath has prepared and filed (or received an appropriate
     extension of time to file) all federal, state, local and foreign returns,
     forms, estimates, information statements, reports and other documents
     ("Returns") required to be filed relating to any and all Taxes concerning
     or attributable to NeoPath or its operations and such Returns are true and
     correct in all material respects and have been completed in all material
     respects in accordance with applicable law.

          (ii) NeoPath (A) has paid all Taxes set forth and shown as due on its
     Returns and (B) has withheld and paid (or will pay at the time required)
     all Taxes required to be withheld, including with respect to its employees
     all federal and state income taxes, FICA, FUTA and other Taxes required to
     be withheld.

          (iii) NeoPath is not delinquent in any material respect in the payment
     of any Tax nor is there any material Tax deficiency outstanding, proposed
     or assessed against NeoPath, nor has NeoPath executed any waiver of any
     statute of limitations on, or any consent extending, the period for the
     assessment or collection of any Tax.

          (iv) No audit or other examination of any Return of NeoPath is
     currently in progress, nor has NeoPath been notified of any request for
     such an audit or other examination.

          (v) NeoPath did not have, as of March 31, 1999, any liabilities,
     whether asserted or unasserted, contingent or otherwise, for unpaid
     federal, state, local and foreign Taxes which have not been accrued or
     reserved against in accordance with GAAP on the NeoPath Interim Balance
     Sheet, and NeoPath has not incurred any such liabilities since such date
     except in the ordinary course of business and consistent with past
     practices.

          (vi) There are (and as of immediately following the Effective Date
     there will be) no liens, pledges, charges, claims, security interests or
     other encumbrances of any sort ("Liens") of a material nature on the assets
     of NeoPath relating to or attributable to Taxes, except for Liens for Taxes
     not yet due and payable or that are being contested in good faith by
     appropriate proceedings.

          (vii) NeoPath has not received written or oral notice of any claim
     relating or attributable to Taxes that, if adversely determined, would
     result in any Lien on the assets of NeoPath.

          (viii) None of NeoPath's assets are treated as "tax-exempt use
     property" within the meaning of Section 168(h) of the Code.

          (ix) As of the Effective Time, there will not be any contract,
     agreement, plan or arrangement, including but not limited to the provisions
     of this Agreement, covering any employee or former employee of NeoPath
     that, individually or collectively, could give rise to the payment of any
     amount that would not be deductible pursuant to Section 280G of the Code or
     the limitations in Section 162(m) of the Code.

          (x) NeoPath has not filed any consent agreement under Section 341(f)
     of the Code or agreed to have Section 341(f)(2) of the Code apply to any
     disposition of a subsection (f) asset (as defined in Section 341(f)(4) of
     the Code) owned by NeoPath.

                                        8


<PAGE>   14

          (xi) NeoPath is not a party to any tax sharing or allocation
     agreements, arrangements or practices nor does NeoPath owe any amount under
     any such agreement, arrangement or practice.

          (xii) NeoPath is not nor has been at any time during the period
     specified in Section 897(c)(1)(A)(ii) of the Code, a "United States real
     property holding corporation" within the meaning of Section 897(c)(2) of
     the Code.

          (xiii) NeoPath has not agreed to, or is required to, make any
     adjustments under Section 481(c) of the Code by reason of a change in
     accounting method or otherwise.

     2.11  Compliance with Laws.

     (a) NeoPath is not in violation in any material respect of any order,
judgment, injunction, award or decree, or any federal, state, local or foreign
law, ordinance or regulation or any other requirement of any governmental or
regulatory body, court or arbitrator, and is in compliance in all material
respects with all of the foregoing that are applicable to it, its business or
its assets. NeoPath has not received notice of, and there has not been any
citation, fine or penalty imposed or asserted against any of them for, any such
violation or alleged violation that has not been favorably and fully resolved.

     (b) NeoPath holds all licenses, permits, certificates, franchises, orders
or approvals of any federal, state, local or foreign governmental or regulatory
body, that are material to the conduct of NeoPath's business and the uses of its
assets necessary to operate its business as presently conducted, other than
those (i) which are ministerial in nature and which NeoPath has no reason to
believe would not be issued in due course and (ii) which, the failure of NeoPath
to possess, would not result in a NeoPath Material Adverse Effect (the "NeoPath
Permits"). The NeoPath Disclosure Schedule contains a true and complete list of
all such NeoPath Permits as of the date hereof. Such NeoPath Permits are in full
force and effect and the validity and effectiveness of such NeoPath Permits will
not be affected by the transactions contemplated hereby. No violations are or
have been recorded with any governmental or regulatory body in respect of any
NeoPath Permit, no proceeding is pending or, to the best knowledge of NeoPath,
threatened to revoke or limit any NeoPath Permit, and NeoPath knows of no
grounds for any such revocation or limitation.

     2.12  Consents; No Breach.  All consents, permits, authorizations and
approvals from any person or entity that are required pursuant to applicable
law, or agreement or otherwise in connection with the execution, delivery and
performance of this Agreement by NeoPath are set forth in Section 2.12 of the
NeoPath Disclosure Schedule, other than those which the failure to obtain would
reasonably be expected to have a NeoPath Material Adverse Effect. Subject to any
prior approval requirements set forth in Section 2.12 of the NeoPath Disclosure
Schedule, the execution, delivery and performance of this Agreement and the
consummation of the transactions contemplated hereby will not (i) violate any
provision of the Articles of Incorporation or Bylaws of NeoPath; (ii) violate,
conflict with or result in the breach of any of the terms or conditions of,
result in a material modification of, or otherwise give any other contracting
party the right to terminate, or constitute (or with notice or lapse of time or
both constitute) a default under, any material instrument, contract or other
agreement to which NeoPath is a party or to which NeoPath or any of their assets
or properties is bound or subject; (iii) violate any statute, law or regulation
of any jurisdiction or any order, judgment, injunction, award or decree of any
court, arbitrator or governmental or regulatory body applicable to or binding
upon NeoPath or any of their securities, properties, assets or business; (iv)
violate any material Permit; (v) require any filing with, notice to, or approval
or consent of any foreign, federal, state, local or other governmental or
regulatory body or any other person or entity; (vi) give rise to any obligation
to make any material payment; or (vii) result in the creation of any material
lien or encumbrance on the assets or properties of NeoPath, excluding from the
foregoing clauses (ii), (iii), (iv) and (v) any exceptions to the foregoing
that, in the aggregate, would not reasonably be expected to have a NeoPath
Material Adverse and the following: (y) the filing of the Merger Documents with
the Secretary of State of the State of Washington and the Secretary of State of
the State of Delaware and (z) the filing with the SEC of (A) the Proxy Statement
(as defined in Section 4.9 below) and (B) such reports under Section 13(a),
13(d), 15(d) or

                                        9


<PAGE>   15

16(a) of the Exchange Act as may be required in connection with this Agreement
and the transactions contemplated hereby and thereby.

     2.13  Actions and Proceedings.  There are no outstanding orders, judgments,
injunctions, awards or decrees of any court, governmental or regulatory body or
arbitration tribunal against or involving NeoPath or any of its securities,
assets, or properties. Except as set forth in the NeoPath Disclosure Schedule,
there are no actions, suits or claims or legal, judicial, administrative or
arbitral proceedings or investigations (whether or not the defense thereof or
liabilities in respect thereof are covered by insurance) pending or, to the best
knowledge of NeoPath, threatened against or involving NeoPath or any of its
securities, assets or properties, that if determined adverse to NeoPath, would
have a NeoPath Material Adverse Effect.

     2.14  Contracts and Other Agreements.  Section 2.14 of the NeoPath
Disclosure Schedule sets forth a correct and complete list all of the following
currently effective contracts:

          (a) written contracts and other agreements with or for the benefit of
     any current or former officer, director, stockholder or employee of NeoPath
     involving more than $25,000 (provided, in the case of a loan by NeoPath to
     any such person, the NeoPath Disclosure Schedule shall list all such loan
     arrangements, whether or not in writing, involving at least $1,000), and
     contracts and other agreements for the payment of fees or other
     consideration to any entity in which NeoPath has an interest;

          (b) contracts and other agreements with any labor union or association
     representing any employee of NeoPath or otherwise providing for any form of
     collective bargaining;

          (c) contracts and other agreements for the purchase or sale of
     materials, supplies, equipment, merchandise or services that contain an
     escalation, renegotiation or redetermination clause or that obligate
     NeoPath to purchase all or substantially all of its requirements of a
     particular product from a supplier, or for periodic minimum purchases of a
     particular product from a supplier;

          (d) contracts and other agreements for the sale of any of the assets
     or properties of NeoPath other than in the ordinary course of business or
     for the grant to any person of any options, rights of first refusal, or
     preferential or similar rights to purchase any of such assets or
     properties;

          (e) partnership or joint venture agreements;

          (f) contracts with agents or foreign representatives regarding the
     sales or marketing of the services or products of NeoPath;

          (g) contracts or other agreements under which NeoPath agrees to act as
     surety or guarantor for or to indemnify any party (other than required
     indemnification provisions in customer contracts) or to share the tax
     liability of any party;

          (h) contracts, options, outstanding purchase orders and other
     agreements for the purchase of any material asset, tangible or intangible;

          (i) contracts and other agreements with customers, suppliers or other
     parties for the sharing of fees, the rebating of charges or other similar
     arrangements other than such contracts entered into in the normal course of
     business;

          (j) contracts and other agreements containing obligations or
     liabilities of any kind to holders of the securities of NeoPath as such
     (including, without limitation, an obligation to register any of such
     securities under any federal or state securities laws) and contracts
     obligating NeoPath to issue or repurchase any securities;

          (k) contracts and other agreements containing covenants of NeoPath not
     to compete in any line of business or with any person or entity or
     covenants of any other person or entity not to compete with NeoPath in any
     line of business;

          (l) contracts and other agreements relating to the acquisition by
     NeoPath of any operating business or the capital stock of any other person
     or entity;


                                       10
<PAGE>   16

          (m) contracts and other agreements requiring the payment to any party
     of a brokerage or sales commission or a finder's or referral fee;

          (n) contracts, indentures, mortgages, promissory notes, debentures
     loan agreements, guaranties, security agreements, pledge agreements, and
     other agreements and instruments relating to the borrowing or lending of
     money or securing any such liability in an amount greater than $50,000;

          (o) any agreement or series of related agreements requiring aggregate
     payments by or to NeoPath of more than $50,000;

          (p) contracts under which NeoPath will acquire or has acquired
     ownership of, or license to, intangible property, including software other
     than commercially available end-user licenses; and

          (q) any other contract or other agreement whether or not made in the
     ordinary course of business, the absence of which would have a NeoPath
     Material Adverse Effect.

     There have been delivered or made available to AutoCyte true and complete
copies of all of the contracts and other agreements (and all amendments, waivers
or other modifications thereto) set forth in Section 2.14 of the NeoPath
Disclosure Schedule. All of such contracts and other agreements are valid,
subsisting, in full force and effect, binding upon NeoPath (as the case may be),
and to the best knowledge of NeoPath, binding upon the other parties thereto in
accordance with their terms. Other than defaults which would not, either singly
or in the aggregate, have a NeoPath Material Adverse Effect, NeoPath is not in
default under any of such scheduled contracts, nor, to the best knowledge of
NeoPath, is any other party to any such contract or other agreement in default
thereunder, nor does any condition exist that constitutes or with notice or
lapse of time or both would constitute a default thereunder.

     2.15  Real Property; Leases.  NeoPath does not own any real property or any
buildings or other structures or has any options or any contractual obligations
to purchase or acquire any interest in real property. Section 2.15 of the
NeoPath Disclosure Schedule sets forth a correct and complete list of all leases
of real property to which NeoPath is a party (collectively, the "NeoPath
Leases"). True and complete copies of the NeoPath Leases and all amendments,
modifications and supplemental agreements thereto have been delivered by NeoPath
to AutoCyte. The NeoPath Leases are in full force and effect and, to the best
knowledge of NeoPath, are binding and enforceable against each of the parties
thereto in accordance with their respective terms. To the best knowledge of
NeoPath, no party to any NeoPath Lease has given notice to any other party
thereto claiming the existence or occurrence of a breach or default thereunder
and there has not occurred any event or circumstances which constitutes, or with
the passage of time or the giving of notice or both would constitute, a breach
or default thereunder, other than defaults which would not, either singly or in
the aggregate, have a NeoPath Material Adverse Effect.

     2.16  Tangible Property.  NeoPath has good and marketable title to, free
and clear of all encumbrances, or otherwise has the unrestricted right to use,
each item of equipment, furniture, leasehold improvements, fixtures, vehicles,
structures, any related capitalized items and other tangible property material
to the business of NeoPath ("NeoPath Tangible Property"). All such NeoPath
Tangible Property is in good and sufficient operating condition and repair,
ordinary wear and tear excepted, and, to the best knowledge of NeoPath, NeoPath
has not received notice that any of the NeoPath Tangible Property is in
violation of any existing law or any building, zoning, health, safety or other
ordinance, code or regulation.

     2.17  Intellectual Property.

     (a) NeoPath owns, or is licensed to use, or otherwise has the right to use
all patents, trademarks, service marks, trade names, trade secrets, logos,
franchises, and copyrights, and all applications for any of the foregoing, and
all technology, inventions, trade secrets, know-how, computer software and
processes that are material in the conduct of its business as now conducted
(collectively, the "NeoPath Proprietary Rights"). NeoPath has previously
delivered to AutoCyte a list of all such patents and registered copyrights and
trademarks, and all applications therefor (the "NeoPath Registered Rights"). All
of the NeoPath Registered Rights owned by NeoPath, and to the best knowledge of
NeoPath, all NeoPath Registered Rights licensed to NeoPath have been registered
in, filed in or issued by the United States Patent and Trademark Office, the



                                       11
<PAGE>   17

United States Register of Copyrights, or the corresponding offices of other
jurisdictions as identified in Section 2.17 of the NeoPath Disclosure Schedule,
and have been properly maintained and renewed in accordance with all applicable
provisions of law and administrative regulations in the United States and in
each such other jurisdiction.

     (b) To the best knowledge of NeoPath, (i) the businesses of NeoPath as
currently conducted does not infringe upon the proprietary rights of others, nor
has NeoPath received any notice or claim from any third party of such
infringement by NeoPath, (ii) there is not any material unlicensed infringement
by any third party on, or any issued competing claim of right to use or own any
of, the NeoPath Proprietary Rights and (iii) none of the activities of the
employees of NeoPath on behalf of NeoPath violates any agreements or
arrangements that any such employees have with former employers.

     2.18  Title to Assets; Liens.  NeoPath owns outright, leases or rents, and
has good title to all of its material assets and properties, including, without
limitation, all of the assets and properties reflected on the NeoPath Interim
Balance Sheet, free and clear of any encumbrance, except for (i) assets and
properties disposed of in the ordinary course of business and as disclosed on
the NeoPath Disclosure Schedule, (ii) encumbrances securing the claims of
materialmen, carriers, landlords and like persons, all of which are not yet due
and payable, (iii) liens for taxes not yet due and payable or for taxes being
contested in good faith by appropriate proceedings or (iv) encumbrances
reflected on the NeoPath Interim Balance Sheet.

     2.19  Employee Benefit Plans.  Section 2.19 of the NeoPath Disclosure
Schedule sets forth a correct and complete list of all pension, profit sharing,
retirement, deferred compensation, welfare, insurance, disability, bonus,
vacation pay, severance pay and similar plans, programs or arrangements,
including without limitation all employee benefit plans as defined in Section
3(3) of the Employee Retirement Income Security Act of 1974, as amended
("ERISA") with respect to which NeoPath is the "Plan Sponsor" within the meaning
of Section 3(16)(B) of ERISA, or in which NeoPath participates (the "NeoPath
Plans"). Each NeoPath Plan which is intended to be qualified under Section
401(a) or 501(c)(9) of the Internal Revenue Code of 1986, as amended (the
"Code"), has received a favorable determination letter from the Internal Revenue
Service that remains in effect. Each NeoPath Plan has been maintained, operated,
funded and administered in all material respects in accordance with the terms of
such NeoPath Plan and the provisions of any and all applicable statutes, orders
or governmental rules and regulations, including without limitation ERISA and
the Code. To the best knowledge of NeoPath, nothing has occurred or failed to
occur with respect to any NeoPath Plan which is intended to comply with Section
401(a) or 501(c)(9) of the Code that would adversely affect the qualified status
of such NeoPath Plan or result in any material liability on the part of NeoPath
including, without limitation, under Title I of ERISA or Section 4975 of the
Code (other than changes in applicable law for which the remedial amendment
period has not yet expired). All material reports, returns, notices and
documents required to be filed with respect to all NeoPath Plans, including
without limitation annual reports on Form 5500, have been timely filed, except
for any failures as could not reasonably be expected to result in a material
liability (either individually or in the aggregate) to NeoPath. All
contributions required by law or the terms of any NeoPath Plan have been made.
All claims for welfare benefits incurred by employees of NeoPath on or before
the Closing are or will be fully covered by third-party insurance policies or
programs. Neither NeoPath nor any of its ERISA Affiliates maintains or
contributes to, or has ever maintained or contributed to (or been obligated to
contribute to), any multiemployer plan as defined in Section 4001(a)(3) of
ERISA, any employee benefit plan that is subject to Section 412 of the Code or
Section 302 of ERISA or any employee benefit plan that is subject to Title IV of
ERISA. Neither NeoPath nor any NeoPath Plan provides or has any obligation to
provide (or contribute toward the cost of) health benefits with respect to any
current or former, officer, employee, agent, director or independent contractor
of NeoPath or any other entity beyond such individual's retirement or other
termination of service, other than as required by applicable law, including
without limitation, Section 4980B(f) of the Code and Sections 601 through 608 of
ERISA. There are no actions, suits or claims (other than routine claims for
benefits) pending or, to the best knowledge of NeoPath, threatened with respect
to (or against the assets of) any NeoPath Plan, nor, to the best knowledge of
NeoPath, is there a reasonable basis for any such action, suit or claim. No
NeoPath Plan is currently under investigation, audit or review, directly or
indirectly, by the IRS, the Department of Labor (the "DOL") or any other
governmental entity or agency, and, to the best knowledge


                                       12
<PAGE>   18

of NeoPath, no such action is contemplated or under consideration by the IRS,
the DOL or any other governmental entity or agency. Complete copies of the
following documents with respect to each NeoPath Plan (as applicable) have been
delivered to AutoCyte: (i) each relevant NeoPath Plan document, as currently in
effect, and subsequent amendment thereto; (ii) each trust agreement, group
annuity contract, insurance policy or contract, as currently in effect; (iii)
each Form 5500 series annual report with each required schedule and attachment
for each of the three (3) most recent plan years; (iv) the most recent IRS
determination letter; and (v) the most recent summary plan description and each
summary of material modification thereto. An "ERISA Affiliate" of NeoPath means
any corporation, trade, business or other entity (whether or not incorporated)
that together with NeoPath would have been deemed a "single employer" within the
meaning of Section 414(b), (c), (m) or (o) of the Code at any time within the
five-year period ending on the Closing Date.

     2.20  Employee Relations.  NeoPath has approximately 150 full-time
equivalent employees and generally enjoys good employer-employee relations.
NeoPath's employees are not represented by any labor union. NeoPath is not
delinquent in payments to any of its employees or consultants for any wages,
salaries, commissions, bonuses or other direct compensation for any services
performed by them to the date hereof or amounts required to be reimbursed to
such employees or consultants. Neither NeoPath, AutoCyte nor the Surviving
Corporation will by reason of the Merger or anything done prior to the Closing
be liable to any NeoPath employee for severance pay or any other payments (other
than accrued salary, vacation or sick pay in accordance with NeoPath's normal
policies) in the event any such employees are terminated. Each employee of
NeoPath has executed NeoPath's standard form of Confidential Information,
Inventions and Noncompetition Agreement. Correct and complete information as to
all current directors, officers, employees or consultants of NeoPath including,
in each case, name, current job title and annual rate of compensation has been
provided by NeoPath to AutoCyte.

     2.21  Relationships with Affiliates.  To the best knowledge of NeoPath, no
officer or director of NeoPath has directly or indirectly any interest in (i)
any property or assets of NeoPath (except as a stockholder of NeoPath), (ii) any
competitor or customer of NeoPath, (iii) any supplier or lender to NeoPath or
(iv) any party to any material contract or agreement with NeoPath.

     2.22  Insurance.  Section 2.22 of the NeoPath Disclosure Schedule sets
forth a correct and complete list of all policies or binders of fire, liability,
product liability, workmen's compensation, vehicular, directors' and officers'
and other insurance held by or on behalf of NeoPath specifying in each case the
type and scope of coverage, the amount of coverage, the premium, the insurer,
the expiration date and all claims made thereunder within the past three years.
Such policies and binders are in full force and effect, are reasonably believed
to be adequate for the businesses engaged in by NeoPath, are in conformity with
the requirements of all leases or other agreements to which NeoPath is a party
and are valid and enforceable in accordance with their terms. All premiums due
under such policies and binders have been paid, and NeoPath is not in default
with respect to any provision contained in any such policy or binder nor has
NeoPath failed to give any notice or present any claim under any such policy or
binder in due and timely fashion. There are no outstanding unpaid claims under
any such policy or binder. NeoPath has not received notice of cancellation or
non-renewal of, or any material amendment to, or any material increase in
deductibles or premiums under, any such policy or binder. Correct and complete
copies of certificates of insurance with respect to all such policies and
binders have been provided by NeoPath to AutoCyte.

     2.23  Brokerage.  Except as set forth in the NeoPath Disclosure Schedule,
no broker, finder, agent or similar intermediary has acted on behalf of NeoPath
in connection with this Agreement or the transactions contemplated hereby, and
there are no brokerage commissions, finders fees or similar fees or commissions
payable in connection therewith based on any agreement, arrangement or
understanding with, or any action taken by NeoPath.

     2.24  Hazardous Materials.  NeoPath has not generated, used or handled any
Hazardous Materials (as defined below), nor has NeoPath treated, stored or
disposed of any Hazardous Materials at any site owned or leased at any time by
NeoPath or shipped any Hazardous Materials for treatment, storage or disposal at
any other site or facility, except in compliance with all applicable laws. To
the best knowledge of NeoPath, no


                                       13
<PAGE>   19

other person has generated, used, handled, stored or disposed of any Hazardous
Materials at any site owned or premises leased by NeoPath at any time or at any
site in which NeoPath presently holds a mortgage or similar interest, nor has
there been or is there threatened any release of any Hazardous Materials on or
at any such site or premises. NeoPath does not presently operate or lease, nor
has it operated or leased, any site on which underground storage tanks are or
were located and which tanks are the responsibility of NeoPath to operate. To
the best knowledge of NeoPath, without investigation, no lien has been imposed
by any governmental agency in connection with the presence of any Hazardous
Materials on any property, facility, machinery, or equipment operated or leased
by NeoPath or in which NeoPath holds any mortgage, lien, or similar interest.
For purposes of this Section 2.24, "Hazardous Materials" shall mean and include
any "hazardous waste" as defined in either the United States Resource
Conservation and Recovery Act, 42 U.S.C. sec. 6901, or regulations adopted
pursuant to said Act, and also any "hazardous substances" or "hazardous
materials" as defined in the United States Comprehensive Environmental Response,
Compensation and Liability Act, 42 U.S.C. sec. 9601, but excludes ordinary and
customary materials in quantities reasonably required to be used by NeoPath in
the ordinary course of NeoPath's business.

     2.25  Registration Statement; Proxy Statement.  The information supplied or
to be supplied by NeoPath specifically for inclusion or incorporation by
reference in (i) the Registration Statement (as defined in Section 4.9 below) to
be filed with the SEC by AutoCyte in connection with the issuance of AutoCyte
Common Stock in the Merger will not, at the time the Registration Statement
becomes effective under the Securities Act of 1933, as amended (the "Securities
Act"), contain any untrue statement of a material fact or omit to state any
material fact required to be stated therein or necessary to make the statements
therein not misleading or (ii) the Proxy Statement (as defined in Section 4.9
below) will not, at the date it is first mailed to the stockholders of NeoPath
and at the time of the special meeting of stockholders of NeoPath held pursuant
to Section 4.10 hereof, contain any untrue statement of a material fact or omit
to state any material fact required to be stated therein or necessary to make
the statements therein, in light of the circumstances under which they were
made, not misleading. The Proxy Statement will comply as to form in all material
respects with the requirements of the Exchange Act and the rules and regulations
thereunder. Notwithstanding this Section 2.25, no representation or warranty is
made by NeoPath with respect to statements made or incorporated by reference
therein based on information supplied by AutoCyte specifically for inclusion or
incorporation by reference in the Proxy Statement.

     2.26  Opinion of Financial Adviser.  NeoPath has received the opinion of
Credit Suisse First Boston Corporation, dated the date of this Agreement, to the
effect that, as of such date and based upon and subject to the matters set forth
therein, the Exchange Ratio is fair from a financial point of view to the
holders of NeoPath Common Stock (other than AutoCyte and its Subsidiaries), a
signed copy of which opinion has been or will promptly be delivered to AutoCyte.

     2.27  Accounting Matters.  To the best knowledge of NeoPath, neither
NeoPath nor any of its affiliates has taken or agreed to take any action that
would prevent the business combination to be effected by the Merger to be
accounted for as a pooling of interests.

     2.28  Full Disclosure.  No representation, warranty or statement of NeoPath
made in this Agreement or in any Exhibit or the NeoPath Disclosure Schedule
attached hereto or in any document, statement or certificate furnished to
AutoCyte pursuant to this Agreement, when taken as a whole, contains any untrue
statement of a material fact or omits to state a material fact required to be
stated therein or necessary to make the statements made, in light of the
circumstance under which they were made, not false or misleading.

            SECTION 3 -- REPRESENTATIONS AND WARRANTIES OF AUTOCYTE

     Except as set forth on the disclosure schedule (the "AutoCyte Disclosure
Schedule") delivered to NeoPath on the date hereof (regardless of whether the
AutoCyte Disclosure Schedule is referenced in any particular subsection of this
Section 3), the subsection numbers of which are numbered to correspond to the


                                       14
<PAGE>   20

subsection numbers of this Agreement to which they refer, AutoCyte and Merger
Sub represent and warrant to NeoPath as set forth below:

     3.1  Organization and Qualification.  Each of AutoCyte and Merger Sub is a
corporation duly organized, validly existing and in good standing under the laws
of the state or other jurisdiction of its incorporation and has full corporate
power and authority to own, lease and operate its assets, properties and
business and to carry on its business as now being and as heretofore conducted.
AutoCyte is qualified or is otherwise authorized to transact business as a
foreign corporation in each jurisdiction (in the United States and outside of
the United States) in which the failure to so qualify would have an AutoCyte
Material Adverse Effect, all of which jurisdictions are identified in Section
3.1 of the AutoCyte Disclosure Schedule.

     3.2  Capitalization.

     (a)  Outstanding Capital Stock.  AutoCyte's authorized capital stock
consists of 20,650,000 shares of Common Stock, $.01 par value per share, of
which 14,282,676 shares are issued and outstanding as of June 3, 1999, and
1,000,000 shares of Preferred Stock, $.01 par value per share, of which no
shares are issued and outstanding. Merger Sub's authorized capital stock
consists of 1,000 shares of Common Stock, $.01 par value per share, all of which
are issued and outstanding as of June 3, 1999. All of the outstanding shares of
Merger Sub are owned by AutoCyte. Except as disclosed in AutoCyte's proxy
statement for its annual meeting of stockholders held on May 26, 1999, AutoCyte
is not aware of any record or beneficial holder of more than five percent (5%)
of the outstanding shares of AutoCyte Stock. The outstanding shares of AutoCyte
Stock and Merger Sub capital stock are duly authorized, validly issued, fully
paid, and nonassessable and have been issued in compliance with all charter
documents of AutoCyte and Merger Sub, respectively, and all applicable federal
and state laws. Except as set forth in this Section 4.2(a), no other capital
stock of AutoCyte or Merger Sub is authorized or outstanding.

     (b)  Options or Other Rights.  Section 3.2(b) of the AutoCyte Disclosure
Schedule lists each outstanding option to acquire shares of AutoCyte Common
Stock under the AutoCyte, Inc. Amended and Restated 1996 Equity Incentive Plan
or the AutoCyte, Inc. 1997 Director Stock Option Plan as of the date hereof, the
name of the holder of such option, the number of shares subject to such option,
the exercise price of such option, the number of shares as to which such option
will have vested at such date and whether the exercisability of such option will
be accelerated in any way by the transactions contemplated by this Agreement or
for any other reason, and indicates the extent of acceleration, if any. Except
as set forth in the AutoCyte Disclosure Schedule, (i) no subscription, warrant,
option, preemptive right, convertible security or other right (contingent or
otherwise) to purchase or acquire any shares of capital stock or other security
of AutoCyte or Merger Sub issued by AutoCyte or Merger Sub is authorized or
outstanding, (ii) there is no commitment or offer by AutoCyte or Merger Sub to
issue or provide any such subscription, warrant, option, preemptive right,
convertible security or other right or to issue or distribute to holders of any
shares of its capital stock any evidences of indebtedness or assets of AutoCyte
or Merger Sub, (iii) neither AutoCyte nor Merger Sub has any obligation
(contingent or otherwise) to purchase, redeem or otherwise acquire any shares of
its capital stock or any interest therein or to pay any dividend or make any
other distribution in respect thereof, (iv) there are no restrictions on the
transfer of capital stock of AutoCyte or Merger Sub other than those arising
from securities laws, and (v) there are no voting trusts, proxies or other
agreements, instruments or understandings with respect to outstanding shares of
AutoCyte's or Merger Sub's capital stock to which AutoCyte or Merger Sub is a
party.

     3.3  Authority to Execute and Perform Agreements.  Each of AutoCyte and
Merger Sub has the requisite corporate power and authority to execute and
deliver this Agreement and each agreement, document and instrument contemplated
by this Agreement to which it is a party and, subject to the requirement to
obtain stockholder approval under the DGCL and the Marketplace Rules of the
Nasdaq Stock Market, to consummate the transactions contemplated hereby and
thereby and to perform fully its respective obligations hereunder and
thereunder. The execution, delivery and performance of this Agreement and each
such other agreement, document and instrument to which it is a party and the
consummation of the transactions contemplated hereby and thereby have been duly
authorized by all necessary corporate action on the part of AutoCyte and Merger
Sub, as appropriate, subject, in the case of the Merger, to the requirement to
obtain


                                       15
<PAGE>   21

stockholder approval under the DGCL and the Marketplace Rules of the Nasdaq
Stock Market. This Agreement and each agreement, document and instrument
executed and delivered by AutoCyte and Merger Sub pursuant to this Agreement
constitutes, or when executed and delivered will constitute, valid and binding
obligations of AutoCyte and Merger Sub, enforceable in accordance with their
terms, subject to bankruptcy, insolvency, fraudulent transfer, reorganization,
moratorium and similar laws of general applicability relating to or affecting
creditors' rights and to general principles of equity.

     3.4  Subsidiaries and Other Affiliates.  Except as set forth in the
AutoCyte Disclosure Schedule, AutoCyte does not have any subsidiary or directly
or indirectly own or have any investment in any of the capital stock of, or any
other interest in, any other person or entity other than Merger Sub.

     3.5  Charter and By-laws; Books and Records.  Each of AutoCyte and Merger
Sub has heretofore delivered or made available to NeoPath true and complete
copies of its Certificate of Incorporation (certified by the Secretary of State
or comparable authority of its jurisdiction of incorporation) and Bylaws as in
effect on the date hereof, and corporate minute books. Neither AutoCyte nor
Merger Sub is in default in the performance, observation or fulfillment of
either its charter or Bylaws. The minute books of AutoCyte and Merger Sub
contain true and complete records of all meetings and consents in lieu of
meetings of the Board of Directors and of the stockholders of AutoCyte and
Merger Sub, respectively, prior to the date hereof, and accurately reflect all
transactions referred to in such minutes and consents in lieu of meetings.

     3.6  SEC Reports.  AutoCyte has previously delivered to NeoPath its (i)
Annual Report on Form 10-K for the year ended December 31, 1998 (the "AutoCyte
10-K") and 1997, as filed with SEC, (ii) the proxy statement relating to
AutoCyte's annual meeting of stockholders held on May 26, 1999 and (iii) all
other reports filed by AutoCyte with the SEC under the Exchange Act, since
January 1, 1998 (the "AutoCyte SEC Documents"). As of their respective dates,
the AutoCyte SEC Documents complied as to form in all material respects with
applicable SEC requirements and, except to the extent that information contained
in the AutoCyte SEC Documents has been revised and superseded by a later filed
AutoCyte SEC Document, did not contain any untrue statement of a material fact
or omit to state a material fact required to be stated therein or necessary to
make the statements therein, in light of the circumstances under which they were
made, not misleading. AutoCyte has timely filed with the SEC all reports
required to be filed under Sections 13, 14 or 15(d) of the Exchange Act since
January 1, 1998.

     3.7  Financial Statements.  The consolidated financial statements contained
in the AutoCyte 10-K and in AutoCyte's quarterly report on Form 10-Q for the
quarter ended March 31, 1999 (the "AutoCyte 10-Q") have been prepared from, and
are in accordance with, the books and records of AutoCyte and fairly present the
consolidated financial condition, results of operations and cash flows of
AutoCyte as of the dates and for the periods presented therein, all in
accordance with generally accepted accounting principles applied on a consistent
basis, except as otherwise indicated therein and subject (in the case of the
unaudited financial statements included in the AutoCyte 10-Q) to normal
period-end and audit adjustments and footnote disclosures, which in the
aggregate are not material.

     3.8  Absence of Undisclosed Liabilities.  Except as set forth in the
AutoCyte Disclosure Schedule, at December 31, 1998, AutoCyte had no material
liabilities of any nature, whether accrued, absolute, contingent or otherwise
(including without limitation, liabilities as guarantor or otherwise with
respect to obligations of others or liabilities for taxes due or then accrued or
to become due), required to be reflected or disclosed in the balance sheet dated
December 31, 1998 (or the notes thereto) included in the AutoCyte 10-K (the
"AutoCyte Balance Sheet") that were not adequately reflected or reserved against
on such balance sheet. Except as set forth in the AutoCyte Disclosure Schedule,
AutoCyte has no such liabilities, except as and to the extent (i) adequately
reflected and reserved against in the AutoCyte Balance Sheet, (ii) adequately
reflected and reserved against in the AutoCyte unaudited balance sheet dated
March 31, 1999 included in the AutoCyte 10-Q (the "AutoCyte Interim Balance
Sheet") or (iii) incurred since December 31, 1998 in the ordinary course of
business.


                                       16
<PAGE>   22

     3.9  No Material Adverse Change.  Except as set forth in the AutoCyte
Disclosure Schedule, since March 31, 1999, except as set forth in the AutoCyte
Disclosure Schedule, there has not been:

          (a) any event or occurrence that could reasonably be expected to have
     an AutoCyte Material Adverse Effect;

          (b) any material change in the method of operating the business of
     AutoCyte or Merger Sub, in the manner of keeping the books, accounts or
     records of AutoCyte or Merger Sub, or in any accounting method or practice
     of AutoCyte or Merger Sub;

          (c) any sale, lease, mortgage, pledge, encumber, abandonment or
     disposition of, or agreement to sell, lease, mortgage, pledge, encumber,
     abandon or dispose of, any material assets or properties of AutoCyte or
     Merger Sub, other than in the usual and ordinary course of business;

          (d) any material transaction, commitment, contract or agreement
     entered into by AutoCyte or Merger Sub, or any relinquishment or
     abandonment by AutoCyte or Merger Sub of any material contract or right, or
     any modification, waiver, amendment, release, recision, or termination of
     any material term, condition or provision of any contract to which AutoCyte
     or Merger Sub is a party and is or should be set forth on the AutoCyte
     Disclosure Schedule in accordance with Section 3.14 (other than any
     satisfaction by performance in accordance with the terms thereof), other
     than in the usual and ordinary course of business;

          (e) any adverse relationships or conditions with employees, suppliers,
     lenders, customers or governmental agencies that could reasonably be
     anticipated to have an AutoCyte Material Adverse Effect;

          (f) any acquisition by AutoCyte or Merger Sub (other than property or
     interests therein acquired in the ordinary course of its lending business)
     of all or any part of the assets, properties, capital stock or business of
     any other person or entity;

          (g) any redemption or other acquisition by AutoCyte or Merger Sub of
     any of its capital stock or any declaration, setting aside or payment of
     any dividend or distribution of any kind with respect to shares of its
     capital stock;

          (h) any loan or advance by AutoCyte or Merger Sub to any stockholder,
     officer, director or consultant, or any other loan or advance other than in
     the ordinary course of business;

          (i) any cancellation, nonrenewal, material reduction in limits or
     coverage or material premium increase for all insurance policies maintained
     by AutoCyte;

          (j) except as set forth in the AutoCyte Disclosure Schedule, any new
     employment or consulting agreement, any increase in compensation, bonus or
     other benefits payable or to become payable by AutoCyte or Merger Sub to
     any director, officer or employee, other than regularly scheduled increases
     consistent with past practice in the ordinary course of business, or any
     new grant of severance or termination rights, or increase in rights or
     benefits payable under existing severance or termination policies or
     agreements, to any director, officer or employee of AutoCyte or Merger Sub;
     or

          (k) commitment, understanding or agreement by AutoCyte nor Merger Sub
     or any of its officers or employees to do any of the things described in
     the preceding classes (a) through (i) (other than this Agreement).

     3.10  Tax Matters.  Except as set forth in the AutoCyte Disclosure
Schedule:

          (a) AutoCyte has prepared and filed (or received an appropriate
     extension of time to file) all Returns required to be filed relating to any
     and all Taxes concerning or attributable to AutoCyte or its operations and
     such Returns are true and correct in all material respects and have been
     completed in all material respects in accordance with applicable law.



                                       17
<PAGE>   23

          (b) AutoCyte (i) has paid all Taxes shown as due on its Returns and
     (ii) has withheld and paid (or will pay at the time required) all Taxes
     required to be withheld, including with respect to its employees all
     federal and state income taxes, FICA, FUTA and other Taxes required to be
     withheld.

          (c) AutoCyte is not delinquent in any material respect in the payment
     of any Tax nor is there any material Tax deficiency outstanding, proposed
     or assessed against AutoCyte, nor has AutoCyte executed any waiver of any
     statute of limitations on, or any consent extending, the period for the
     assessment or collection of any Tax.

          (d) No audit or other examination of any Return of AutoCyte is
     currently in progress, nor has AutoCyte been notified of any request for
     such an audit or other examination.

          (e) AutoCyte did not have, as of March 31, 1999, any liabilities,
     whether asserted or unasserted, contingent or otherwise, for unpaid
     federal, state, local and foreign Taxes which have not been accrued or
     reserved against in accordance with GAAP on the AutoCyte Interim Balance
     Sheet, and AutoCyte has not incurred any such liabilities since such date
     except in the ordinary course of business and consistent with past
     practices.

          (f) There are (and as of immediately following the Effective Date
     there will be) no Liens of a material nature on the assets of AutoCyte
     relating to or attributable to Taxes, except for Liens for Taxes not yet
     due and payable or that are being contested in good faith by appropriate
     proceedings.

          (g) AutoCyte has not received written or oral notice of any claim
     relating or attributable to Taxes that, if adversely determined, would
     result in any Lien on the assets of AutoCyte.

          (h) None of AutoCyte's assets are treated as "tax-exempt use property"
     within the meaning of Section 168(h) of the Code.

          (i) As of the Effective Time, there will not be any contract,
     agreement, plan or arrangement, including but not limited to the provisions
     of this Agreement, covering any employee or former employee of AutoCyte
     that, individually or collectively, could give rise to the payment of any
     amount that would not be deductible pursuant to Section 280G of the Code or
     the limitations in Section 162(m) of the Code.

          (j) AutoCyte has not filed any consent agreement under Section 341(f)
     of the Code or agreed to have Section 341(f)(2) of the Code apply to any
     disposition of a subsection (f) asset (as defined in Section 341(f)(4) of
     the Code) owned by AutoCyte.

          (k) AutoCyte is not a party to any tax sharing or allocation
     agreements, arrangements or practices nor does AutoCyte owe any amount
     under any such agreement, arrangement or practice.

          (l) AutoCyte is not nor has been at any time during the period
     specified in Section 897(c)(1)(A)(ii) of the Code, a "United States real
     property holding corporation" within the meaning of Section 897(c)(2) of
     the Code.

          (m) AutoCyte has not agreed to, nor is it required to, make any
     adjustments under Section 481(c) of the Code by reason of a change in
     accounting method or otherwise.

     3.11  Compliance with Laws.

     (a) Neither AutoCyte nor Merger Sub is in violation in any material respect
of any order, judgment, injunction, award or decree, or any federal, state,
local or foreign law, ordinance or regulation or any other requirement of any
governmental or regulatory body, court or arbitrator, and is in compliance in
all material respects with all of the foregoing that are applicable to it, its
business or its assets. Neither AutoCyte nor Merger Sub has received notice of,
and there has not been any citation, fine or penalty imposed or asserted against
any of them for, any such violation or alleged violation that has not been
favorably and fully resolved.

     (b) Each of AutoCyte and Merger Sub holds all licenses, permits,
certificates, franchises, orders or approvals of any federal, state, local or
foreign governmental or regulatory body, that are material to the conduct of
AutoCyte's business and the uses of its assets necessary to operate its business
as presently


                                       18
<PAGE>   24

conducted, other than those (i) which are ministerial in nature and which
AutoCyte has no reason to believe would not be issued in due course and (ii)
which, the failure of AutoCyte or Merger Sub to possess, would result in an
AutoCyte Material Adverse Effect (the "AutoCyte Permits"). The AutoCyte
Disclosure Schedule contains a true and complete list of all such AutoCyte
Permits as of the date hereof. Such AutoCyte Permits are in full force and
effect and the validity and effectiveness of such AutoCyte Permits will not be
affected by the transactions contemplated hereby. No violations are or have been
recorded with any governmental or regulatory body in respect of any AutoCyte
Permit, no proceeding is pending or, to the best knowledge of AutoCyte,
threatened to revoke or limit any AutoCyte Permit, and AutoCyte knows of no
grounds for any such revocation or limitation.

     3.12  Consents; No Breach.  All consents, permits, authorizations and
approvals from any person or entity that are required pursuant to applicable
law, or agreement or otherwise in connection with the execution, delivery and
performance of this Agreement by AutoCyte and Merger Sub are set forth in
Section 3.12 of the AutoCyte Disclosure Schedule, other than those which the
failure to obtain would reasonably be expected to have an AutoCyte Material
Adverse Effect. Subject to any prior approval requirements set forth in Section
3.12 of the AutoCyte Disclosure Schedule, the execution, delivery and
performance of this Agreement and the consummation of the transactions
contemplated hereby will not (i) violate any provision of the Certificate of
Incorporation or Bylaws of AutoCyte or Merger Sub; (ii) violate, conflict with
or result in the breach of any of the terms or conditions of, result in a
material modification of, or otherwise give any other contracting party the
right to terminate, or constitute (or with notice or lapse of time or both
constitute) a default under, any material instrument, contract or other
agreement to which AutoCyte or Merger Sub is a party or to which either of
AutoCyte or Merger Sub or any of its assets or properties is bound or subject;
(iii) violate any statute, law or regulation of any jurisdiction or any order,
judgment, injunction, award or decree of any court, arbitrator or governmental
or regulatory body applicable to or binding upon AutoCyte or Merger Sub or its
securities, properties, assets or business; (iv) violate any material AutoCyte
Permit; (v) require any filing with, notice to, or approval or consent of any
foreign, federal, state, local or other governmental or regulatory body or any
other person or entity; (vi) give rise to any obligation to make any material
payment; or (vii) result in the creation of any material lien or encumbrance on
the assets or properties of AutoCyte or Merger Sub, excluding from the foregoing
clauses (ii), (iii), (iv) and (v) any exceptions to the foregoing that, in the
aggregate, would not reasonably to expected to have an AutoCyte Material Adverse
Effect and the following: (w) the filing of the Merger Documents with the
Secretary of State of the State of Washington and the Secretary of State of the
State of Delaware, (x) filings with various state blue sky authorities, (y) the
filing with Nasdaq of an application for listing of the shares of AutoCyte
Common Stock to be issued in the Merger and (z) the filing with the SEC of (A)
the Proxy Statement (as defined in Section 4.9 below), (B) the Registration
Statement (as defined in Section 4.9 below) and (C) such reports under Section
13(a), 13(d), 15(d) or 16(a) of the Exchange Act as may be required in
connection with this Agreement and the transaction contemplated hereby and
thereby.

     3.13  Actions and Proceedings.  There are no outstanding orders, judgments,
injunctions, awards or decrees of any court, governmental or regulatory body or
arbitration tribunal against or involving AutoCyte or Merger Sub or any of its
securities, assets, or properties. There are no actions, suits or claims or
legal, judicial, administrative or arbitral proceedings or investigations
(whether or not the defense thereof or liabilities in respect thereof are
covered by insurance) pending or, to the best knowledge of AutoCyte, threatened
against or involving AutoCyte or Merger Sub or any of its securities, assets or
properties that if determined adverse to AutoCyte or Merger Sub would have an
AutoCyte Material Adverse Effect.

     3.14  Contracts and Other Agreements.  Section 3.14 of the AutoCyte
Disclosure Schedule sets forth a correct and complete list all of the following
currently effective contracts:

          (a) written contracts and other agreements with or for the benefit of
     any current or former officer, director, stockholder or employee of
     AutoCyte involving more than $25,000 (provided, in the case of a loan by
     AutoCyte to any such person, the AutoCyte Disclosure Schedule shall list
     all such loan arrangements, whether or not in writing, involving at least
     $1,000), and contracts and other agreements for the payment of fees or
     other consideration to any entity in which AutoCyte has an interest;


                                       19
<PAGE>   25

          (b) contracts and other agreements with any labor union or association
     representing any employee of AutoCyte or otherwise providing for any form
     of collective bargaining;

          (c) contracts and other agreements for the purchase or sale of
     materials, supplies, equipment, merchandise or services that contain an
     escalation, renegotiation or redetermination clause or that obligate
     AutoCyte to purchase all or substantially all of its requirements of a
     particular product from a supplier, or for periodic minimum purchases of a
     particular product from a supplier;

          (d) contracts and other agreements for the sale of any of the assets
     or properties of AutoCyte other than in the ordinary course of business or
     for the grant to any person of any options, rights of first refusal, or
     preferential or similar rights to purchase any of such assets or
     properties;

          (e) partnership or joint venture agreements;

          (f) contracts with agents or foreign representatives regarding the
     sales or marketing of AutoCyte's services or products;

          (g) contracts or other agreements under which AutoCyte agrees to act
     as surety or guarantor for or to indemnify any party (other than required
     indemnification provisions in customer contracts) or to share the tax
     liability of any party;

          (h) contracts, options, outstanding purchase orders and other
     agreements for the purchase of any material asset, tangible or intangible;

          (i) contracts and other agreements with customers, suppliers or other
     parties for the sharing of fees, the rebating of charges or other similar
     arrangements other than such contracts entered into in the normal course of
     business;

          (j) contracts and other agreements containing obligations or
     liabilities of any kind to holders of the securities of AutoCyte as such
     (including, without limitation, an obligation to register any of such
     securities under any federal or state securities laws) and contracts
     obligating AutoCyte to issue or repurchase any AutoCyte securities;

          (k) contracts and other agreements containing covenants of AutoCyte
     not to compete in any line of business or with any person or entity or
     covenants of any other person or entity not to compete with AutoCyte in any
     line of business;

          (l) contracts and other agreements relating to the acquisition by
     AutoCyte of any operating business or the capital stock of any other person
     or entity;

          (m) contracts and other agreements requiring the payment to any party
     of a brokerage or sales commission or a finder's or referral fee;

          (n) contracts, indentures, mortgages, promissory notes, debentures
     loan agreements, guaranties, security agreements, pledge agreements, and
     other agreements and instruments relating to the borrowing or lending of
     money or securing any such liability in an amount greater than $50,000;

          (o) any agreement or series of related agreements requiring aggregate
     payments by or to AutoCyte of more than $50,000;

          (p) contracts under which AutoCyte will acquire or has acquired
     ownership of, or license to, intangible property, including software other
     than commercially available end-user licenses; and

          (q) any other material contract or other agreement whether or not made
     in the ordinary course of business, the absence of which would have an
     AutoCyte Material Adverse Effect.

     Merger Sub is not a party to any contract or agreement other than the
agreement contemplated hereby. There have been delivered or made available to
NeoPath true and complete copies of all of the contracts and other agreements
(and all amendments, waivers or other modifications thereto) set forth in
Section 3.14 of the AutoCyte Disclosure Schedule. All of such contracts and
other agreements are valid, subsisting, in full force and effect, binding upon
AutoCyte, and to the best knowledge of AutoCyte, binding upon the other parties



                                       20
<PAGE>   26

thereto in accordance with their terms. Other than defaults which would not,
either singly or in the aggregate, have an AutoCyte Material Adverse Effect,
AutoCyte is not in default under any of such scheduled contracts, nor, to the
best knowledge of AutoCyte, is any other party to any such contract or other
agreement in default thereunder, nor does any condition exist that constitutes
or with notice or lapse of time or both would constitute a default thereunder.

     3.15  Real Property; Leases.  Neither AutoCyte nor Merger Sub owns any real
property or any buildings or other structures and does not have any options or
any contractual obligations to purchase or acquire any interest in real
property. Section 3.15 of the AutoCyte Disclosure Schedule sets forth a correct
and complete list of all leases of real property to which AutoCyte or Merger Sub
is a party (collectively, the "AutoCyte Leases"). True and complete copies of
the AutoCyte Leases and all amendments, modifications and supplemental
agreements thereto have been delivered by AutoCyte to NeoPath. The AutoCyte
Leases are in full force and effect and, to the best knowledge of AutoCyte, are
binding and enforceable against each of the parties thereto in accordance with
their respective terms. To the best knowledge of AutoCyte, no party to any
AutoCyte Lease has given notice to any other party thereto claiming the
existence or occurrence of a breach or default thereunder and there has not
occurred any event or circumstances which constitutes, or with the passage of
time or the giving of notice or both would constitute, a breach or default
thereunder, other than defaults which would not, either singly or in the
aggregate, have an AutoCyte Material Adverse Effect.

     3.16  Tangible Property.  Each of AutoCyte and Merger Sub has good and
marketable title to, free and clear of all encumbrances, or otherwise has the
unrestricted right to use, each item of equipment, furniture, leasehold
improvements, fixtures, vehicles, structures, any related capitalized items and
other tangible property material to the business of AutoCyte ("AutoCyte Tangible
Property"). All such AutoCyte Tangible Property is in good and sufficient
operating condition and repair, ordinary wear and tear excepted, and, to the
best knowledge of AutoCyte, AutoCyte has not received notice that any of the
AutoCyte Tangible Property is in violation of any existing law or any building,
zoning, health, safety or other ordinance, code or regulation.

     3.17  Intellectual Property.

     (a) AutoCyte owns, or is licensed to use, or otherwise has the right to use
all patents, trademarks, service marks, trade names, trade secrets, logos,
franchises, and copyrights, and all applications for any of the foregoing, and
all technology, inventions, trade secrets, know-how, computer software and
processes that are material in the conduct of its business as now conducted
(collectively, the "AutoCyte Proprietary Rights"). AutoCyte has previously
delivered to NeoPath a list of all such patents and registered copyrights and
trademarks, and all applications therefor (the "AutoCyte Registered Rights").
All of the AutoCyte Registered Rights owned by AutoCyte, and to the best
knowledge of AutoCyte, all AutoCyte Registered Rights licensed to AutoCyte, have
been registered in, filed in or issued by the United States Patent and Trademark
Office, the United States Register of Copyrights, or the corresponding offices
of other jurisdictions as identified in Section 3.17 of the AutoCyte Disclosure
Schedule, and have been properly maintained and renewed in accordance with all
applicable provisions of law and administrative regulations in the United States
and in each such other jurisdiction.

     (b) To the best knowledge of AutoCyte, (i) the business of AutoCyte as
currently conducted does not infringe upon the proprietary rights of others, nor
has AutoCyte received any notice or claim from any third party of such
infringement by AutoCyte, (ii) there is not any material unlicensed infringement
by any third party on, or any issued competing claim of right to use or own any
of, the AutoCyte Proprietary Rights of AutoCyte and (iii) none of the activities
of the employees of AutoCyte on behalf of AutoCyte violates any agreements or
arrangements that any such employees have with former employers.

     3.18  Title to Assets; Liens.  AutoCyte owns outright, leases or rents, and
has good title to all of its material assets and properties, including, without
limitation, all of the assets and properties reflected on the AutoCyte Interim
Balance Sheet, free and clear of any encumbrance, except for (i) assets and
properties disposed of in the ordinary course of business and as disclosed in
the AutoCyte Disclosure Schedule, (ii) encumbrances securing the claims of
materialmen, carriers, landlords and like persons, all of which are not yet due
and payable, (iii) liens for taxes not yet due and payable or for taxes being
contested in good faith by appropriate proceedings or (iv) encumbrances
reflected on the AutoCyte Interim Balance Sheet.



                                       21
<PAGE>   27

     3.19  Employee Benefit Plans.  Section 4.19 of the AutoCyte Disclosure
Schedule sets forth a correct and complete list of all pension, profit sharing,
retirement, deferred compensation, welfare, insurance, disability, bonus,
vacation pay, severance pay and similar plans, programs or arrangements,
including without limitation all employee benefit plans as defined in Section
3(3) of the Employee Retirement Income Security Act of 1974, as amended
("ERISA") with respect to which AutoCyte is the "Plan Sponsor" within the
meaning of Section 3(16)(B) of ERISA, or in which AutoCyte participates (the
"AutoCyte Plans"). Each AutoCyte Plan which is intended to be qualified under
Section 401(a) or 501(c)(9) of the Internal Revenue Code of 1986, as amended
(the "Code"), has received a favorable determination letter from the Internal
Revenue Service that remains in effect. Each AutoCyte Plan has been maintained,
operated, funded and administered in all material respects in accordance with
the terms of such AutoCyte Plan and the provisions of any and all applicable
statutes, orders or governmental rules and regulations, including without
limitation ERISA and the Code. To the best knowledge of AutoCyte, nothing has
occurred or failed to occur with respect to any AutoCyte Plan which is intended
to comply with Section 401(a) or 501(c)(9) of the Code that would adversely
affect the qualified status of such AutoCyte Plan or result in any material
liability on the part of AutoCyte including, without limitation, under Title I
of ERISA or Section 4975 of the Code (other than changes in applicable law for
which the remedial amendment period has not yet expired). All material reports,
returns, notices and documents required to be filed with respect to all AutoCyte
Plans, including without limitation annual reports on Form 5500, have been
timely filed, except for any failures as could not reasonably be expected to
result in a material liability (either individually or in the aggregate) to
AutoCyte. All contributions required by law or the terms of any AutoCyte Plan
have been made. All claims for welfare benefits incurred by employees of
AutoCyte on or before the Closing are or will be fully covered by third-party
insurance policies or programs. Neither AutoCyte nor any of its ERISA Affiliates
maintains or contributes to, or has ever maintained or contributed to (or been
obligated to contribute to), any multiemployer plan as defined in Section
4001(a)(3) of ERISA, any employee benefit plan that is subject to Section 412 of
the Code or Section 302 of ERISA or any employee benefit plan that is subject to
Title IV of ERISA. Neither AutoCyte nor any AutoCyte Plan provides or has any
obligation to provide (or contribute toward the cost of) health benefits with
respect to any current or former, officer, employee, agent, director or
independent contractor of AutoCyte or any other entity beyond such individual's
retirement or other termination of service, other than as required by applicable
law, including without limitation, Section 4980B(f) of the Code and Sections 601
through 608 of ERISA. There are no actions, suits or claims (other than routine
claims for benefits) pending or, to the best knowledge of AutoCyte, threatened
with respect to (or against the assets of) any AutoCyte Plan, nor, to the best
knowledge of AutoCyte, is there a reasonable basis for any such action, suit or
claim. No AutoCyte Plan is currently under investigation, audit or review,
directly or indirectly, by the IRS, the DOL or any other governmental entity or
agency, and, to the best knowledge of AutoCyte, no such action is contemplated
or under consideration by the IRS, the DOL or any other governmental entity or
agency. Complete copies of the following documents with respect to each AutoCyte
Plan (as applicable) have been delivered to NeoPath: (i) each relevant AutoCyte
Plan document, as currently in effect, and subsequent amendment thereto; (ii)
each trust agreement, group annuity contract, insurance policy or contract, as
currently in effect; (iii) each Form 5500 series annual report with each
required schedule and attachment for each of the three (3) most recent plan
years; (iv) the most recent IRS determination letter; and (v) the most recent
summary plan description and each summary of material modification thereto. An
"ERISA Affiliate" of AutoCyte means any corporation, trade, business or other
entity (whether or not incorporated) that together with AutoCyte would have been
deemed a "single employer" within the meaning of Section 414(b), (c), (m) or (o)
of the Code at any time within the five-year period ending on the Closing Date.

     3.20  Employee Relations.  AutoCyte has approximately 83 full-time
equivalent employees and generally enjoys good employer-employee relations. None
of AutoCyte's employees are represented by any labor union. AutoCyte is not
delinquent in payments to any of its employees or consultants for any wages,
salaries, commissions, bonuses or other direct compensation for any services
performed by them to the date hereof or amounts required to be reimbursed to
such employees or consultants. AutoCyte will not by reason of the Merger or
anything done prior to the Closing be liable to any AutoCyte employees for
severance pay or any other payments (other than accrued salary, vacation or sick
pay in accordance with AutoCyte's normal policies) in the event any such
employees are terminated. Each employee of AutoCyte has executed


                                       22
<PAGE>   28

AutoCyte's standard form of Confidentiality and Assignment of Inventions
Agreement. Correct and complete information as to all current directors,
officers, employees or consultants of AutoCyte including, in each case, name,
current job title and annual rate of compensation has been provided by AutoCyte
to NeoPath.

     3.21  Relationships with Affiliates.  Except as set forth in Section 3.21
of the AutoCyte Disclosure Schedule, to the best knowledge of AutoCyte, no
officer or director of AutoCyte has directly or indirectly any interest in (i)
any property or assets of AutoCyte (except as a stockholder of AutoCyte), (ii)
any competitor or customer of AutoCyte, (iii) any supplier or lender to AutoCyte
or (iv) any party to any material contract or agreement with AutoCyte.

     3.22  Insurance.  Section 3.22 of the AutoCyte Disclosure Schedule sets
forth a correct and complete list of all policies or binders of fire, liability,
product liability, workmen's compensation, vehicular, directors' and officers'
and other insurance held by or on behalf of AutoCyte specifying in each case the
type and scope of coverage, the amount of coverage, the premium, the insurer,
the expiration date and all claims made thereunder within the past three years.
Such policies and binders are in full force and effect, are reasonably believed
to be adequate for the businesses engaged in by AutoCyte, are in conformity with
the requirements of all leases or other agreements to which AutoCyte is a party
and are valid and enforceable in accordance with their terms. All premiums due
under such policies and binders have been paid, and AutoCyte is not in default
with respect to any provision contained in any such policy or binder nor has
AutoCyte failed to give any notice or present any claim under any such policy or
binder in due and timely fashion. There are no outstanding unpaid claims under
any such policy or binder. AutoCyte has not received notice of cancellation or
non-renewal of, or any material amendment to, or any material increase in
deductibles or premiums under, any such policy or binder. Correct and complete
copies of certificates of insurance with respect to all such policies and
binders have been provided by AutoCyte to NeoPath.

     3.23  Brokerage.  No broker, finder, agent or similar intermediary has
acted on behalf of AutoCyte or Merger Sub in connection with this Agreement or
the transactions contemplated hereby, and there are no brokerage commissions,
finders fees or similar fees or commissions payable in connection therewith
based on any agreement, arrangement or understanding with, or any action taken
by AutoCyte or Merger Sub.

     3.24  Hazardous Materials.  Neither AutoCyte nor Merger Sub has generated,
used or handled any Hazardous Materials (as defined below), nor has AutoCyte or
Merger Sub treated, stored or disposed of any Hazardous Materials at any site
owned or leased at any time by AutoCyte or Merger Sub or shipped any Hazardous
Materials for treatment, storage or disposal at any other site or facility,
except in compliance with all applicable laws. To the knowledge of AutoCyte, no
other person has generated, used, handled, stored or disposed of any Hazardous
Materials at any site owned or premises leased by AutoCyte or Merger Sub at any
time or at any site in which AutoCyte or Merger Sub presently holds a mortgage
or similar interest, nor has there been or is there threatened any release of
any Hazardous Materials on or at any such site or premises. Neither AutoCyte nor
Merger Sub presently operates or leases, nor has either operated or leased, any
site on which underground storage tanks are or were located and which tanks are
the responsibility of AutoCyte or Merger Sub to operate. To the best knowledge
of AutoCyte, without investigation, no lien has been imposed by any governmental
agency in connection with the presence of any Hazardous Materials on any
property, facility, machinery, or equipment operated or leased by AutoCyte or
Merger Sub or in which AutoCyte or Merger Sub holds any mortgage, lien, or
similar interest. For purposes of this Section 3.24, "Hazardous Materials" shall
mean and include any "hazardous waste" as defined in either the United States
Resource Conservation and Recovery Act, 42 U.S.C. sec. 6901, or regulations
adopted pursuant to said Act, and also any "hazardous substances" or "hazardous
materials" as defined in the United States Comprehensive Environmental Response,
Compensation and Liability Act, 42 U.S.C. sec. 9601, but excludes ordinary and
customary materials in quantities reasonably required to be used by AutoCyte in
the ordinary course of AutoCyte's business.

     3.25  Registration Statement; Proxy Statement.  The information supplied or
to be supplied by AutoCyte specifically for inclusion or incorporation by
reference in (i) the Registration Statement (as defined in Section 4.9 below) to
be filed with the SEC by AutoCyte in connection with the issuance of AutoCyte
Common Stock in the Merger will not, at the time the Registration Statement
becomes effective under the


                                       23
<PAGE>   29

Securities Act, contain any untrue statement of a material fact or omit to state
any material fact required to be stated therein or necessary to make the
statements therein not misleading or (ii) the Proxy Statement (as defined in
Section 4.9 below) will not, at the date it is first mailed to the stockholders
of AutoCyte and at the time of the special meeting of stockholders of AutoCyte
held pursuant to Section 4.11 hereof, contain any untrue statement of a material
fact or omit to state any material fact required to be stated therein or
necessary to make the statements therein, in light of the circumstances under
which they were made, not misleading. The Proxy Statement will comply as to form
in all material respects with the requirements of the Exchange Act and the rules
and regulations thereunder. Notwithstanding this Section 3.25, no representation
or warranty is made by AutoCyte with respect to statements made or incorporated
by reference therein based on information supplied by NeoPath specifically for
inclusion or incorporation by reference in the Proxy Statement.

     3.26  Opinion of Financial Adviser.  AutoCyte has received the opinion of
Warburg Dillon Read LLC, dated the date of this Agreement, to the effect that,
as of such date, the Merger is fair from a financial point of view to the
holders of AutoCyte Common Stock (other than NeoPath and its affiliates), a
signed copy of which opinion has been or will promptly be delivered to NeoPath.

     3.27  Accounting Matters.  To the best knowledge of AutoCyte, neither
AutoCyte nor any of its affiliates has taken or agreed to take any action that
would prevent the business combination to be effected by the Merger to be
accounted for as a pooling of interests.

     3.28  Full Disclosure.  No representation, warranty or statement of
AutoCyte or Merger Sub made in this Agreement or in any Exhibit or the AutoCyte
Disclosure Schedule attached hereto or in any document, statement or certificate
furnished to NeoPath pursuant to this Agreement, when taken as a whole, contains
any untrue statement of a material fact or omits to state a material fact
required to be stated therein or necessary to make the statements made, in light
of the circumstance under which they were made, not false or misleading.

                     SECTION 4 -- COVENANTS AND AGREEMENTS

     The parties covenant and agree as follows:

     4.1  Conduct of NeoPath Business.  Except with the prior written consent of
AutoCyte and except as otherwise contemplated herein or as set forth in the
NeoPath Disclosure Schedule, during the period from the date hereof to the
Closing Date, NeoPath shall observe the following covenants:

     (a) Affirmative Covenants Pending Closing.  NeoPath will:

          (i) Preservation of Personnel.  Use all reasonable efforts to preserve
     intact their business organizations and keep available the services of
     present employees, in each case in accordance with past practice, it being
     understood that termination of employees with poor performance ratings
     shall not constitute a violation of this covenant;

          (ii) Insurance.  Use all reasonable efforts to keep in effect all
     insurance coverage that was in force as of March 31, 1999, including, but
     not limited to (A) policies insuring loss or destruction of, or damage to,
     property, (B) third party liability policies such as, but not limited to,
     commercial general liability, automobile liability, employers liability,
     and umbrella liability, (C) workers compensation insurance, (D) directors
     and officers liability, (E) policies insuring employees for health, dental,
     life and accident benefits on a group basis;

          (iii) Preservation of the Business; Maintenance of Properties,
     Contracts.  Use all reasonable efforts to preserve their businesses,
     advertise, promote and market their services, keep their properties intact,
     preserve their goodwill and maintain all physical properties in good
     operating condition;

          (iv) Intellectual Property Rights.  Use all reasonable efforts to
     preserve and protect the NeoPath Proprietary Rights; and

          (v) Ordinary Course of Business.  Operate their businesses diligently
     and in the ordinary course.


                                       24
<PAGE>   30

     (b) Negative Covenants Pending Closing.  NeoPath will not:

          (i) Disposition of Assets.  Sell or transfer, or mortgage, pledge or
     create or permit to be created any encumbrance on, any of their assets,
     other than sales or transfers in the ordinary course of business and liens
     existing under arrangements disclosed herein or permitted under Section
     2.18;

          (ii) Liabilities.  (A) voluntarily incur any obligation or liability
     other than in the ordinary course of their business (provided that NeoPath
     may incur reasonable and appropriate expenses in connection with this
     transaction), (B) incur any indebtedness for borrowed money or enter into
     any contracts or commitments involving payments by NeoPath of $50,000 or
     more, other than purchase orders or commitments for inventory materials and
     supplies in the ordinary course of business;

          (iii) Compensation.  (A) change the compensation or fringe benefits of
     any officer, director or employee, or (B) enter into or modify any Plan or
     any employment, severance or other agreement with any officer, director or
     employee of NeoPath other than changes required by law to maintain the tax-
     qualified status of any Plan or as otherwise required by law;

          (iv) Capital Stock.  (A) Grant or accelerate the exercisability of,
     any option, warrant or other right to purchase, or to convert any
     obligation into, shares of its capital stock, (B) declare or pay any
     dividend or other distribution with respect to any shares of its capital
     stock, (C) reclassify, combine, split, subdivide or redeem, purchase or
     otherwise acquire, directly or indirectly, any of its capital stock or (D)
     issue any shares of its capital stock, except upon the exercise of options
     outstanding on the date hereof;

          (v) Articles of Incorporation and Bylaws.  Amend the Articles of
     Incorporation or Bylaws of NeoPath;

          (vi) Acquisitions.  Acquire (including, without limitation, by merger,
     consolidation, or acquisition of stock or assets) any corporation,
     partnership, other business organization or any division thereof or acquire
     any material amount of assets or property other than in the ordinary course
     of NeoPath's business;

          (vii) Material Agreements.  Enter into or modify any material
     agreement with any other person or entity (other than agreements in the
     ordinary course of its business involving payments by NeoPath of less than
     $50,000); or

          (viii) Other.  Agree in writing or otherwise to take any of the
     actions described in this Section 4.1(b).

     4.2  Conduct of AutoCyte Business.  Except with the prior written consent
of NeoPath and except as otherwise contemplated herein or as set forth in the
AutoCyte Disclosure Schedule, during the period from the date hereof to the
Closing Date, AutoCyte and Merger Sub shall observe the following covenants:

     (a) Affirmative Covenants Pending Closing.  Each of AutoCyte and Merger Sub
will:

          (i) Preservation of Personnel.  Use all reasonable efforts to preserve
     intact their business organizations and keep available the services of
     present employees, in each case in accordance with past practice, it being
     understood that termination of employees with poor performance ratings
     shall not constitute a violation of this covenant;

          (ii) Insurance.  Use all reasonable efforts to keep in effect all
     insurance coverage that was in force as of March 31, 1999, including, but
     not limited to (A) policies insuring loss or destruction of, or damage to,
     property, (B) third party liability policies such as, but not limited to,
     commercial general liability, automobile liability, employers liability,
     and umbrella liability, (C) workers compensation insurance, (D) directors
     and officers liability, (E) policies insuring employees for health, dental,
     life and accident benefits on a group basis;



                                       25
<PAGE>   31

          (iii) Preservation of the Business; Maintenance of Properties,
     Contracts.  Use all reasonable efforts to preserve their businesses,
     advertise, promote and market their services, keep their properties intact,
     preserve their goodwill and maintain all physical properties in good
     operating condition;

          (iv) Intellectual Property Rights.  Use all reasonable efforts to
     preserve and protect the AutoCyte Proprietary Rights; and

          (v) Ordinary Course of Business.  Operate its business diligently and
     in the ordinary course.

     (b) Negative Covenants Pending Closing.  Neither AutoCyte nor Merger Sub
will:

          (i) Disposition of Assets.  Sell or transfer, or mortgage, pledge or
     create or permit to be created any encumbrance on, any of its assets, other
     than sales or transfers in the ordinary course of business and liens
     existing under arrangements disclosed herein or of the type permitted under
     Section 3.18;

          (ii) Liabilities.  (A) voluntarily incur any obligation or liability
     other than in the ordinary course of their business (provided that AutoCyte
     may incur reasonable and appropriate expenses in connection with this
     transaction), (B) incur any indebtedness for borrowed money or enter into
     any contracts or commitments involving payments by AutoCyte of $50,000 or
     more, other than purchase orders or commitments for inventory materials and
     supplies in the ordinary course of business;

          (iii) Compensation.  (A) Change the compensation or fringe benefits of
     any officer, director or employee, or (B) enter into or modify any Plan or
     any employment, severance or other agreement with any officer, director or
     employee of AutoCyte other than changes required by law to maintain the
     tax-qualified status of any Plan or as otherwise required by law;

          (iv) Capital Stock.  (A) Grant or accelerate the exercisability of,
     any option, warrant or other right to purchase, or to convert any
     obligation into, shares of its capital stock, (B) declare or pay any
     dividend or other distribution with respect to any shares of its capital
     stock, (C) reclassify, combine, split, subdivide or redeem, purchase or
     otherwise acquire, directly or indirectly, any of its capital stock or (D)
     issue any shares of its capital stock, except (i) upon the exercise of
     options outstanding on the date hereof or (ii) in connection with the
     consummation of the transaction contemplated by the Asset Purchase
     Agreement dated as of March 25, 1999 (the "Asset Purchase Agreement")
     between AutoCyte and Neuromedical Systems, Inc. ("NSI");

          (v) Certification of Incorporation and ByLaws.  Amend the
     Certification of Incorporation or Bylaws of AutoCyte;

          (vi) Acquisitions.  Acquire (including, without limitation, by merger,
     consolidation, or acquisition of stock or assets) any corporation,
     partnership, other business organization or any division thereof or acquire
     any material amount of assets or property other than (i) the acquisition of
     the certain assets of NSI that are the subject of the Asset Purchase
     Agreement or (ii) an acquisition (by stock or asset purchase, merger or
     otherwise) of Cell Analysis Systems, Inc. or other acquisitions in the
     ordinary course of AutoCyte's business;

          (vii) Material Agreements.  Enter into or modify any material
     agreement with any other person or entity, other than in the ordinary
     course of its business; or

          (viii) Other.  Agree in writing or otherwise to take any of the
     actions described in this Section 4.2(b).

     4.3  Nasdaq Listing.  AutoCyte shall take such actions as may be necessary
to cause the shares of AutoCyte Common Stock to be issued hereunder to be
approved for quotation on the Nasdaq National Market.

     4.4  Corporate Examinations and Investigations.  Prior to the Effective
Time, each of AutoCyte and NeoPath shall be entitled, through its employees and
representatives, to have such access to the assets, properties, business, books,
records and operations of the other as AutoCyte or NeoPath, as the case may be,
shall reasonably request in connection with such party's investigation of the
other with respect to the


                                       26
<PAGE>   32

transaction contemplated hereby. Any such investigation or examination shall be
conducted at reasonable times and the party being investigated shall cooperate
fully therein. For the purposes of this Agreement, actual knowledge shall mean
the conscious knowledge of the executive officers of a party who have given
substantive attention to this transaction. In order that each of AutoCyte and
NeoPath may have full opportunity to make such investigation, the party being
investigated shall furnish the representatives of the other during such period
with all such information and copies of such documents concerning the affairs of
the party being investigated as such representatives may reasonably request and
cause its officers, employees, consultants, agents, accountants and attorneys to
cooperate fully with such representatives in connection with such investigation.

     4.5  Agreement not to Entertain Other Offers.

     (a) In consideration of the efforts and expenses undertaken by both parties
in pursuing the Merger and other valuable consideration, the receipt and
adequacy of which are acknowledged, AutoCyte and NeoPath agree that until the
Closing Date or until this Agreement is otherwise terminated pursuant to Section
8, neither AutoCyte nor NeoPath nor any of their authorized representatives
shall:

          (i) directly or indirectly, solicit any proposal relating to the
     acquisition by another party of all or any portion of the capital stock of
     such company or substantially all of the assets of such company (whether by
     merger or otherwise);

          (ii) directly or indirectly, engage in any discussions or negotiations
     with any other party regarding any such acquisition, or otherwise encourage
     or facilitate any efforts by any other party to engage in such an
     acquisition; or

          (iii) sell, transfer or dispose of all or any portion of the capital
     stock of such company or substantially all of the assets of such company
     (whether by merger or otherwise);

including, without limitation, furnishing to any other person information with
respect to, any effort or attempt by any other person to do or to seek any such
transaction identified in any of the foregoing clauses (i) through (iii);
provided, however, that, notwithstanding the foregoing, each of AutoCyte and
NeoPath and its authorized representatives may participate in discussions or
negotiations with, provide information to, and consummate a transaction with, a
third party that would otherwise be prohibited by this section, if (A) such
discussions or negotiations had been commenced prior to the date hereof or if
commenced after the date hereof, were not solicited by or on behalf of such
company and (B) such discussions or negotiations were being continued or
initiated after the Board of Directors of such company determines in good faith
(after consultation with independent counsel, which may be the company's regular
outside counsel) that such action is necessary for such Board to comply with its
fiduciary duties to its stockholders under applicable law.

     (b) AutoCyte and NeoPath each agree to inform the other orally and in
writing in reasonable detail (including without limitation the applicable terms
and conditions and identity of the other person) within one business day of
receipt of any offer, proposal or inquiry relating to any of the transactions
identified in Section 4.5(a) and of any modification thereof or any proposed
agreement and to promptly furnish to the other copies of any written
communications or documents received with respect to the foregoing.

     4.6  Authorization from Others.  Prior to the Closing Date, the parties
shall use all reasonable efforts to obtain all authorizations, consents and
permits required to permit the consummation of the transactions contemplated by
this Agreement, including without limitation all consents required from third
parties who have contractual relationships with NeoPath.

     4.7  Consummation of Agreement.  Each party shall use all reasonable
efforts to perform and fulfill all conditions and obligations to be performed
and fulfilled by it under this Agreement and to ensure that to the extent within
its control or capable of influence by it, no breach of any of the respective
representations, warranties and agreements hereunder occurs or exists on or
prior to the Effective Time, all to the end that the transactions contemplated
by this Agreement shall be fully carried out in a timely fashion. Without
limiting the generality of the foregoing, each party shall (i) use all
reasonable efforts to defend any lawsuits or other legal proceedings, whether
judicial or administrative, challenging this Agreement or the consummation of
the transactions contemplated by this Agreement, including seeking to have any
stay or temporary restraining



                                       27
<PAGE>   33

order entered by any court or other governmental entity vacated or reversed and
(ii) (A) use all reasonable efforts to ensure that no state takeover statute or
similar statute or regulation is or becomes applicable to the Merger, this
Agreement or any of the other transactions contemplated by this Agreement and
(B) if any state takeover statute or similar statute or regulation becomes
applicable to the Merger, this Agreement or any other transaction contemplated
by this Agreement, use all reasonable efforts to ensure that the Merger and the
other transactions contemplated by this Agreement may be consummated as promptly
as practicable on the terms contemplated by this Agreement and otherwise to
minimize the effect of such statute or regulation on the Merger and the other
transactions contemplated by this Agreement.

     4.8  Further Assurances.  Each of the parties shall execute such documents,
further instruments of transfer and assignment and other papers and take such
further actions as may be reasonably required or desirable to carry out the
provisions hereof and the transactions contemplated hereby.

     4.9  Joint Proxy Statement/Prospectus; Registration Statement.  As soon as
practicable after the date of this Agreement, AutoCyte and NeoPath shall jointly
prepare and file with the SEC, subject to the prior approval of the other party,
which approval shall not be unreasonably withheld, preliminary joint proxy
materials relating to the special meetings of the stockholders of NeoPath and
AutoCyte held in accordance with Sections 4.10 and 4.11 hereof, respectively,
and as required by the Exchange Act, and a Registration Statement on Form S-4
(as amended or supplemented, the "Registration Statement") relating to the
registration under the Securities Act of the shares of AutoCyte Common Stock to
be issued in the Merger. Each of AutoCyte and NeoPath shall use all reasonable
efforts to have the Registration Statement declared effective under the
Securities Act as promptly as practicable after such filing. AutoCyte shall also
use all reasonable efforts to qualify the shares of AutoCyte Common Stock to be
issued in the Merger under the securities or "blue sky" laws of every state
necessary to offer and issue the shares of AutoCyte Common Stock issuable
pursuant to Section 1.6(a) to the stockholders of NeoPath at the Closing, except
any such state with respect to which counsel for AutoCyte has determined that
such qualification is not required under the securities or "blue sky" laws of
such state, and except that in no event shall AutoCyte be obligated to qualify
as a foreign corporation or to execute a general consent to service of process
in any state in which it has not previously so qualified or has not previously
so consented. The joint proxy statement/prospectus included in the Registration
Statement at the time it initially is mailed to the stockholders of AutoCyte and
shareholders of NeoPath and all duly filed supplements, amendments or revisions
made thereto, if any, similarly mailed are hereinafter referred to as the "Proxy
Statement." No filing of, or amendment or supplement to, the Registration
Statement will be made by AutoCyte, or the Proxy Statement will be made by
NeoPath or AutoCyte, without providing the other party the opportunity to review
and comment thereon. If, at any time prior to the Effective Time, any event
relating to either AutoCyte or NeoPath or any of its affiliates, officers or
directors is discovered that is required to be set forth in an amendment to the
Registration Statement or filings under blue sky laws or a supplement to the
Proxy Statement, such party will promptly inform the other party, and such
amendment or supplement will be promptly filed with the SEC and appropriate
state securities administrators and disseminated to the stockholders of AutoCyte
and NeoPath, to the extent required by applicable federal and state securities
laws.

     4.10  NeoPath Stockholder Meeting.  NeoPath, acting through its Board of
Directors, shall, in accordance with applicable law and its Articles of
Incorporation and Bylaws:

          (a) at a special meeting of stockholders of NeoPath and at any
     adjournment thereof, submit to the stockholders a proposal to consider and
     act on this Agreement to obtain such approval required under the WBCA for
     the consummation of the transactions contemplated hereby;

          (b) include in the Proxy Statement to be delivered to the stockholders
     of NeoPath soliciting their approval of the transactions contemplated
     hereby the recommendation of its Board of Directors that the stockholders
     vote in favor of the adoption of this Agreement; and

          (c) use all reasonable efforts (i) to obtain and furnish the
     information required to be included by it in the Proxy Statement, (ii) to
     cause the Proxy Statement to be mailed to its stockholders at the earliest
     practicable time after the effectiveness of the Registration Statement and
     (iii) to obtain the necessary approvals by its stockholders of the
     transactions contemplated hereby.


                                       28
<PAGE>   34

     4.11  AutoCyte Stockholder Meeting.  AutoCyte, acting through its Board of
Directors, shall, in accordance with applicable law and its Certificate of
Incorporation and Bylaws:

          (a) at a special meeting of stockholders of AutoCyte and at any
     adjournment thereof, submit to the stockholders a proposal to obtain such
     approval required pursuant to the Nasdaq Market Rules;

          (b) include in the Proxy Statement to be delivered to the stockholders
     of AutoCyte soliciting their approval of this Agreement and the
     transactions contemplated hereby the recommendation of its Board of
     Directors that the stockholders vote in favor of such transactions; and

          (c) use all reasonable efforts (i) to obtain and furnish the
     information required to be included by it in the Proxy Statement, (ii) to
     cause the Proxy Statement to be mailed to its stockholders at the earliest
     practicable time after the effectiveness of the Registration Statement and
     (iii) to obtain the necessary approvals by its stockholders of this
     Agreement, the Merger and the transactions contemplated hereby.

     4.12  Public Announcements and Confidentiality.  Any press release or other
information to the press or any third party with respect to this Agreement or
the transactions contemplated hereby shall require the prior approval of
AutoCyte and NeoPath, which approval shall not be unreasonably withheld,
provided that a party shall not be prevented from making such disclosure as it
shall be advised by counsel is required by law or any listing agreement with a
national security exchange or the Nasdaq National Market. The parties
acknowledge that AutoCyte and NeoPath have previously executed a
Confidentiality/Non-Disclosure Agreement, dated April 29, 1999 (the
"Confidentiality Agreement"), which Confidentiality Agreement will continue in
full force and effect in accordance with its terms, except as is necessary to
comply with the terms of this Agreement.

     4.13  NeoPath Affiliate Agreements.  Set forth on Section 4.13 of the
NeoPath Disclosure Schedule is a list of those persons who, at the time of the
vote of NeoPath's stockholders on the Merger, NeoPath believes may be
"affiliates" of NeoPath within the meaning of Rule 145 under the Securities Act
or applicable SEC accounting releases with respect to "pooling of interests"
accounting treatment. NeoPath shall use all reasonable efforts to provide
AutoCyte with such information as AutoCyte shall reasonably request for purposes
of reviewing such list. NeoPath shall use its best efforts to deliver or cause
to be delivered to AutoCyte promptly after the date hereof from each of the
affiliates listed in Section 4.13 of the NeoPath Disclosure Schedule an
Affiliate Agreement in substantially the form attached as Exhibit C hereto (the
"NeoPath Affiliate Agreement"), each of which will be in full force and effect
as of the Effective Time. AutoCyte will be entitled to place appropriate legends
on the certificates evidencing any AutoCyte Common Stock to be received by any
such affiliate pursuant to the terms of this Agreement, and to issue appropriate
stop transfer instructions to the transfer agent for the AutoCyte Common Stock,
consistent with the terms of the Affiliate Agreement.

     4.14  AutoCyte Affiliate Agreements.  Set forth on Section 4.14 of the
AutoCyte Disclosure Schedule is a list of those persons who, at the time of the
vote of AutoCyte's stockholders on the Merger, AutoCyte believes may be
"affiliates" of AutoCyte within the meaning of applicable SEC accounting
releases with respect to "pooling of interests" accounting treatment. AutoCyte
shall use all reasonable efforts to provide NeoPath with such information as
NeoPath shall reasonably request for purposes of reviewing such list. AutoCyte
shall use its best efforts to deliver or cause to be delivered to NeoPath
promptly after the date hereof from each of the affiliates listed in Section
4.14 of the AutoCyte Disclosure Schedule an Affiliate Agreement in substantially
the form attached as Exhibit D hereto (the "AutoCyte Affiliate Agreement"), each
of which will be in full force and effect as of the Effective Time.

     4.15  AutoCyte SEC Filings.  Until the Closing Date, AutoCyte shall furnish
NeoPath with a copy of each periodic or current report filed by AutoCyte under
the Exchange Act promptly after filing the same. All filings made by AutoCyte
after the date hereof pursuant to the Exchange Act will be made in a timely
fashion, will comply as to form in all material respects with the applicable
provisions of the Exchange Act and the rules and regulations thereunder and will
not contain any untrue statement of a material fact or omit to state a material
fact required to be stated therein or necessary to make the statements therein,
in light of the circumstances under which they are made, not misleading.



                                       29
<PAGE>   35

     4.16  NeoPath SEC Filings.  Until the Closing Date, NeoPath shall furnish
AutoCyte with a copy of each periodic or current report filed by NeoPath under
the Exchange Act promptly after filing the same. All filings made by NeoPath
after the date hereof pursuant to the Exchange Act will be made in a timely
fashion, will comply as to form in all material respects with the applicable
provisions of the Exchange Act and the rules and regulations thereunder and will
not contain any untrue statement of a material fact or omit to state a material
fact required to be stated therein or necessary to make the statements therein,
in light of the circumstances under which they are made, not misleading.

     4.17  Stock Options; Employee Stock Purchase Plan.

     (a) At the Effective Time, each outstanding option to purchase shares of
NeoPath Common Stock (each a "NeoPath Stock Option") under the NeoPath Stock
Option Plans, whether or not exercisable, will be assumed by AutoCyte. Each
NeoPath Stock Option so assumed by AutoCyte under this Agreement will continue
to have, and be subject to, the same terms and conditions set forth in the
applicable NeoPath Stock Option Plan immediately prior to the Effective Time
(including, without limitation, any repurchase rights), except that (i) each
NeoPath Stock Option will be exercisable (or will become exercisable in
accordance with its terms) for that number of whole shares of AutoCyte Common
Stock equal to the product of the number of shares of NeoPath Common Stock that
were issuable upon exercise of such NeoPath Stock Option immediately prior to
the Effective Time multiplied by the Exchange Ratio, rounded down to the nearest
whole number of shares of AutoCyte Common Stock, and (ii) the per share exercise
price for the shares of AutoCyte Common Stock issuable upon exercise of such
assumed NeoPath Stock Option will be equal to the quotient determined by
dividing the exercise price per share of NeoPath Common Stock at which such
NeoPath Stock Option was exercisable immediately prior to the Effective Time by
the Exchange Ratio, rounded up to the nearest whole cent. After the Effective
Time, AutoCyte will issue to each holder of an outstanding NeoPath Stock Option
a notice describing the foregoing assumption of such NeoPath Stock Option by
AutoCyte.

     (b) It is the intention of the parties that NeoPath Stock Options assumed
by AutoCyte qualify following the Effective Time as incentive stock options as
defined in Section 422 of the Code to the extent NeoPath Stock Options qualified
as incentive stock options immediately prior to the Effective Time; and that
notwithstanding anything contained in Section 1.6(a)(ii) or Section 4.17 hereof,
or any other provision of this Agreement, the exercise price, the number of
shares purchasable and the terms and conditions applicable to any NeoPath Stock
Options shall be determined so as to comply with Sections 422 and 424 of the
Code and the regulations promulgated thereunder.

     (c) The Board of Directors of NeoPath shall, prior to or as of the
Effective Time, take appropriate action to approve the deemed cancellation of
the NeoPath Stock Options for purposes of Section 16(b) of the Exchange Act. The
Board of Directors of AutoCyte shall, prior to or as of the Effective Time, take
appropriate action to approve the deemed grant of options to purchase AutoCyte
Common Stock under the NeoPath Stock Options (as converted pursuant to this
Section 4.17) for purposes of Section 16(b) of the Exchange Act.

     (d) AutoCyte will reserve sufficient shares of AutoCyte Common Stock for
issuance under Section 4.17(a) and under Section 1.6(a)(ii) hereof.

     (e) NeoPath shall not commence any offering under its Employee Stock
Purchase Plan after the date hereof.

     4.18  AutoCyte Form S-8.  AutoCyte agrees to file a registration statement
on Form S-8 for the shares of AutoCyte Common Stock issuable with respect to the
assumed NeoPath Stock Options no later than three business days after the
Effective Time and shall keep such registration statement effective for so long
as any such NeoPath Stock Options remain outstanding.

     4.19  FIRPTA.  At or prior to the Closing, NeoPath, if requested by
AutoCyte and in a form specified by AutoCyte, shall deliver to the IRS a notice
that the NeoPath Common Stock is not a "U.S. Real Property Interest" as defined
and in accordance with the requirements of Treasury Regulation Section
1.897-2(h)(2).


                                       30
<PAGE>   36

     4.20  Notification of Certain Matters.  AutoCyte will give prompt notice to
NeoPath, and NeoPath will give prompt notice to AutoCyte, of the occurrence, or
failure to occur, of any event, which occurrence or failure to occur would be
reasonably likely to cause (a) any representation or warranty contained in this
Agreement to be untrue or inaccurate in any material respect at any time from
the date of this Agreement to the Effective Time or (b) any material failure of
AutoCyte or NeoPath, as the case may be, or of any officer, director, employee
or agent thereof, to comply with or satisfy any covenant, condition or agreement
to be complied with or satisfied by it under this Agreement. Notwithstanding the
above, the delivery of any notice pursuant to this section will not limit or
otherwise affect the remedies available hereunder to the party receiving such
notice or the conditions to such party's obligation to consummate the Merger.

     4.21  Tax-Free Reorganization.  AutoCyte and NeoPath will each use all
reasonable efforts to cause the Merger to be treated as a reorganization within
the meaning of Section 368 of the Code. AutoCyte and NeoPath will each make
available to the other party and their respective legal counsel copies of all
Returns reasonably requested by the other party. AutoCyte and NeoPath will make
such representations as reasonably requested by legal counsel for the purpose of
rendering the opinions contemplated by Section 5.7.

     4.22  Indemnification.  (a) From and after the Effective Time, AutoCyte
shall fulfill and honor in all respects the obligations of NeoPath to indemnify
each person who is or was a director or officer (an "Indemnified Party") of
NeoPath pursuant to any indemnification provisions of NeoPath's Articles of
Incorporation or Bylaws as each is in effect on the date hereof.

     (b) For a period of six years after the Effective Time, AutoCyte shall
cause to be maintained in effect the current officers' and directors' liability
insurance maintained by NeoPath with respect to the Indemnified Parties
(provided that AutoCyte may substitute therefor policies of at least the same
coverage and amounts containing terms and conditions which are no less
advantageous to the Indemnified parties than such existing insurance) covering
acts or omissions occurring prior to the Effective Time; provided, that AutoCyte
shall not be required in order to maintain or procure such coverage to pay an
annual premium in excess of the current annual premium paid by NeoPath for its
existing coverage or, alternatively, a single payment in excess of six times the
current annual premium paid by NeoPath for its existing coverage (the "Cap");
and provided, further, that if existing coverage cannot be maintained or
equivalent coverage cannot be obtained, or can be obtained only by paying an
annual premium in excess of the Cap, AutoCyte shall only be required to obtain
as much coverage as can be obtained by paying an annual premium equal to the
Cap. The current annual premium paid by NeoPath for its existing coverage is set
forth in Section 4.22(a) of the NeoPath Disclosure Schedule.

     (c) This Section 4.22 shall survive the closing of all the transactions
contemplated hereby, is intended to benefit the Indemnified Parties and their
respective heirs and personal representatives to the extent that the provisions
of NeoPath's Articles of Incorporation or Bylaws and NeoPath's current officers'
and directors' liability insurance benefit such individuals (each of which shall
be entitled to enforce this Section 4.22 against AutoCyte as a third-party
beneficiary of this Agreement to such extent).

     4.23  Pooling of Interests.  Each of AutoCyte and NeoPath shall use all
reasonable efforts to cause the transaction contemplated by this Agreement,
including the Merger, to be accounted for as a pooling of interests under
Opinion 16 of the Accounting Principles Board and applicable SEC rules and
regulations, and AutoCyte's and NeoPath's respective management's conclusion
that such accounting treatment is appropriate for the Merger to be concurred
with by each of AutoCyte's and NeoPath's auditors and by the SEC, respectively,
and neither AutoCyte nor NeoPath shall voluntarily take any action that would
cause such accounting treatment not to be obtained.

     4.24  Letters of AutoCyte's and NeoPath's Accountants.  (a) AutoCyte shall
use all reasonable efforts to cause its independent public accountants to
deliver to NeoPath a letter, dated a date within two business days before the
Closing Date, addressed to NeoPath, in form and substance reasonably
satisfactory to NeoPath and customary in scope and substance for comfort letters
delivered by independent public accountants in connection with registration
statements similar to the Registration Statement. AutoCyte shall also provide
reasonable cooperation to each of AutoCyte's and NeoPath's independent public
accountants to enable them to issue the letters referred to in Section 5.7.


                                       31
<PAGE>   37

     (b) NeoPath shall use all reasonable efforts to cause its independent
public accountants to deliver to AutoCyte a letter, dated a date within two
business days before the Closing Date, addressed to AutoCyte, in form and
substance reasonably satisfactory to AutoCyte and customary in scope and
substance for comfort letters delivered by independent public accountants in
connection with registration statements similar to the Registration Statement.
NeoPath shall also provide reasonable cooperation to each of NeoPath's and
AutoCyte's independent public accountants to enable them to issue the letters
referred to in Section 5.7.

     4.25  Employee Benefit Plans; Existing Agreement.  (a) As soon as
practicable after the Effective Time (the "Benefits Date"), AutoCyte shall
provide, or cause to be provided, to each employee of NeoPath employee benefit
plans, programs and arrangements that are the same as those made generally
available to similarly situated non-represented employees of AutoCyte who are
hired by AutoCyte after December 31, 1998. From the Effective Time to the
Benefits Date (which the parties acknowledge may occur on different dates with
respect to different plans, programs or arrangements of NeoPath) (the
"Continuation Period"), AutoCyte shall provide, or cause to be provided, the
employee benefit plans, programs and arrangements of NeoPath provided to
employees of NeoPath as of the date hereof.

     (b) With respect to each benefit plan, program practice, policy or
arrangement maintained by AutoCyte (the "AutoCyte Plans") in which employees of
NeoPath subsequently participate, for purposes of determining vesting and
entitlement to benefits, including for severance benefits and vacation
entitlement (but not for accrual of benefits), service with NeoPath (or
predecessor employers to the extent NeoPath provides past service credit) shall
be treated as service with AutoCyte; provided, that such service shall not be
recognized to the extent that such recognition would result in a duplication of
benefits. Such service also shall apply for purposes of satisfying any waiting
periods, evidence of insurability requirements, or the application of any pre-
existing condition limitations. Each AutoCyte Plan shall waive pre-existing
condition limitations to the same extent waived under the applicable NeoPath
benefit plan. NeoPath employees shall be given credit for amounts paid under a
corresponding benefit plan during the same period for purposes of applying
deductible, copayments and out-of-pocket maximums as though such amounts had
been paid in accordance with the terms and conditions of the AutoCyte Plan.

              SECTION 5 -- CONDITIONS PRECEDENT TO THE OBLIGATIONS
                     OF EACH PARTY TO CONSUMMATE THE MERGER

     The respective obligations of each party to consummate the Merger shall be
subject to the satisfaction or waiver, at or before the Effective Time, of each
of the following conditions:

     5.1  Stockholder Approvals.  All required approvals of the stockholders of
NeoPath, AutoCyte and Merger Sub shall have been obtained.

     5.2  Government Approvals.  All authorizations, consents, orders,
declarations or approvals of, or filings with, any governmental or regulatory
authority, domestic or foreign, which the failure to obtain, make or occur would
have the effect of making the Merger or any of the transactions contemplated
hereby illegal or would have a Material Adverse Effect on AutoCyte or NeoPath,
assuming the Merger had taken place, shall have been obtained, made or occurred.

     5.3  Absence of Restraints.  No judgment, order, decree, statute, law,
ordinance, rule or regulation, entered, enacted, promulgated, enforced or issued
by any court or other governmental entity of competent jurisdiction or other
legal restraint or prohibition (collectively, "restraints") shall be in effect,
and there shall not be pending any suit, action or proceeding by any
governmental entity (i) preventing the consummation of the Merger or (ii) which
otherwise is reasonably likely to have a Material Adverse Effect on AutoCyte or
NeoPath, as applicable; provided, that each of the parties shall have used all
reasonable efforts to prevent the entry of any such restraints and to appeal as
promptly as possible any such restraints that may be entered.

     5.4  Nasdaq Listing.  The shares of AutoCyte Common Stock to be issued in
the Merger shall have been approved for quotation on the Nasdaq National Market.



                                       32
<PAGE>   38

     5.5  Effectiveness of Registration Statement.  The Registration Statement
shall have been declared effective by the SEC and there shall not be any stop
order in effect with respect to the Registration Statement.

     5.6  Tax Opinions.  AutoCyte and NeoPath each shall have received
substantially identical written opinions from their counsel, Palmer & Dodge LLP
and Perkins & Coie LLP, respectively, in form and substance reasonably
satisfactory to them, to the effect that the Merger will constitute a
reorganization within the meaning of Section 368(a) of the Code; provided that
if the respective counsel to AutoCyte or NeoPath does not render such opinion,
this condition shall nonetheless be deemed satisfied with respect to such party
if counsel to the other party renders such opinion to such party.

     5.7  Pooling Letters.  Each of AutoCyte and NeoPath shall have received
letters, dated as of the Closing Date, in each case addressed to AutoCyte and
NeoPath, from Ernst & Young LLP stating in substance that pooling of interests
accounting is appropriate for the Merger under Opinion 16 of the Accounting
Principles Board and applicable SEC rules and regulations.

              SECTION 6 -- CONDITIONS PRECEDENT TO THE OBLIGATION
                      OF AUTOCYTE TO CONSUMMATE THE MERGER

     The obligation of AutoCyte to consummate the Merger is subject to the
satisfaction or waiver by AutoCyte, at or before the Effective Time, of the
following conditions:

     6.1  Representations, Warranties and Covenants.  Each of the
representations and warranties of NeoPath contained in this Agreement to the
extent it is qualified by NeoPath Material Adverse Effect shall be true and
correct and each of the representations and warranties to the extent it is not
so qualified by NeoPath Material Adverse Effect shall be true and correct in all
material respects, in each case, on and as of the Effective Time with the same
force and effect as though made on and as of the Effective Time (with such
exceptions as may be permitted under or contemplated by this Agreement and
except to the extent that such representations and warranties expressly relate
to an earlier date, in which case such representations and warranties shall be
as of such earlier date). NeoPath shall have performed and complied in all
material respects with all covenants and agreements required by this Agreement
to be performed or complied with by them on or prior to the Effective Time.
AutoCyte shall have received from NeoPath a certificate, dated the Closing Date,
to the foregoing effect signed on behalf of NeoPath by the Chief Executive
Officer of NeoPath.

     6.2  NeoPath Affiliate Agreements.  Except as set forth thereon, each of
the individuals and entities listed on Section 4.13 of the NeoPath Disclosure
Schedule shall have entered into a NeoPath Affiliate Agreement in the form
attached hereto as Exhibit C, and such agreements are in full force and effect.

     6.3  Voting Agreement.  Each of the individuals and entities listed on
Section 4.13 of the NeoPath Disclosure Schedule shall have entered into a Voting
Agreement with AutoCyte in the form attached hereto as Exhibit A, and such
agreements shall be in full force and effect.

     6.4  Opinion of Counsel to NeoPath.  AutoCyte shall have received a legal
opinion from Perkins & Coie LLP, counsel to NeoPath, dated the Closing Date and
in form and substance reasonably acceptable to Palmer & Dodge LLP, counsel to
AutoCyte, as to the matters set forth in Exhibit E hereto.

     6.5  Merger Documents.  NeoPath shall have executed and delivered the
Merger Documents referred to in Section 1.2.

     6.6  Consents.  NeoPath shall have received all necessary consents or
waivers from the other parties to each contract, lease or agreement to which
NeoPath is a party, except where the failure to receive such consent would not
reasonably be expected, individually or in the aggregate, to have a NeoPath
Material Adverse Effect.

     6.7  Dissenting Shares.  The Dissenting Shares shall not exceed five
percent (5%) of the shares of the NeoPath Common Stock issued and outstanding or
issuable on the Closing Date.

     6.8  Certificates.  NeoPath shall have furnished AutoCyte with such
documents and certificates as may be reasonably requested by AutoCyte.



                                       33
<PAGE>   39

              SECTION 7 -- CONDITIONS PRECEDENT TO THE OBLIGATION
                      OF NEOPATH TO CONSUMMATE THE MERGER

     The obligation of NeoPath to consummate the Merger is subject to the
satisfaction or waiver by NeoPath, at or before the Effective Time, of the
following conditions:

     7.1  Representations, Warranties and Covenants.  Each of the
representations and warranties of AutoCyte and Merger Sub contained in this
Agreement to the extent it is qualified by AutoCyte Material Adverse Effect
shall be true and correct and each of the representations and warranties to the
extent it is not so qualified by AutoCyte Material Adverse Effect, shall be true
and correct in all material respects on and as of the Effective Time with the
same force and effect as though made on and as of the Effective Time (with such
exceptions as may be permitted under or contemplated by this Agreement and
except to the extent that such representations and warranties expressly relate
to an earlier date, in which case such representations and warranties shall be
as of such earlier date). AutoCyte shall have performed and complied in all
material respects with all covenants and agreements required by this Agreement
to be performed or complied with by it on or prior to the Effective Time.
NeoPath shall have received from AutoCyte a certificate, dated the Closing Date,
to the foregoing effect signed on behalf of AutoCyte by the Chief Executive
Officer of AutoCyte.

     7.2  AutoCyte Affiliate Agreements.  Except as set forth thereon, each of
the individuals and entities listed on Section 4.14 of the AutoCyte Disclosure
Schedule shall have entered into an AutoCyte Affiliate Agreement in the form
attached hereto as Exhibit D, and such agreements are in full force and effect.

     7.3  Voting Agreement.  Each of Richard Charpie, Robert Curry and James
Powell shall have entered into a Voting Agreement with AutoCyte on behalf of
himself and all other entities of which such individuals exercise voting control
in the form attached hereto as Exhibit B, and such agreements shall be in full
force and effect.

     7.4  Consents.  AutoCyte shall have received all necessary consents or
waivers from the other parties to each contract, lease or agreement to which
AutoCyte is a party, except where the failure to receive such consent would not
reasonably be expected, individually or in the aggregate, to have an AutoCyte
Material Adverse Effect.

     7.5  Opinion of Counsel to AutoCyte.  NeoPath shall have received a legal
opinion from Palmer & Dodge LLP, counsel to AutoCyte, dated the Closing Date and
in form and substance reasonably acceptable to Perkins & Coie LLP, counsel to
NeoPath, as to the matters set forth in Exhibit F hereto.

     7.6  Certificates.  AutoCyte shall have furnished NeoPath with such
documents and certificates as may be reasonably requested by NeoPath.

                            SECTION 8 -- TERMINATION

     8.1  Termination.  This Agreement may be terminated at any time on or prior
to the Effective Time of the Merger, whether prior to or after approval by
NeoPath's stockholders or AutoCyte's stockholders, as follows:

     (a) by AutoCyte or NeoPath if, without fault of the terminating party, the
Closing Date shall not have occurred on or before November 30, 1999, which date
may be extended by mutual consent of the parties;

     (b) by AutoCyte upon written notice to NeoPath if any representation or
warranty made herein by NeoPath was not true and correct in all material
respects when made or NeoPath has materially breached any covenant contained
herein and has not cured such breach within ten (10) business days of receipt of
written notice from AutoCyte or by the Closing Date, whichever occurs first;

     (c) by NeoPath upon written notice to AutoCyte if any representation or
warranty of AutoCyte made herein was not true and correct in all material
respects when made or AutoCyte has materially breached any covenant contained
herein and has not cured such breach within ten (10) business days of receipt of
written notice from NeoPath or by the Closing Date, whichever occurs first;



                                       34
<PAGE>   40

     (d) by AutoCyte or NeoPath if any court of competent jurisdiction or
governmental body shall have issued an order, decree or ruling or taken any
other action restraining, enjoining or otherwise prohibiting the Merger and such
order, decree or ruling shall have become final and nonappealable;

     (e) by AutoCyte or NeoPath if either the AutoCyte or NeoPath stockholders
vote and fail to approve the Merger as required by the DGCL or WBCA,
respectively;

     (f) by AutoCyte if NeoPath's Board of Directors (i) fails to include in the
Proxy Statement its recommendation that NeoPath stockholders vote in favor of
the adoption of this Agreement or (ii) withdraws its recommendation that
stockholders vote in favor (other than in connection with exercising NeoPath's
rights to terminate this Agreement pursuant to subsection (c) or (d) of this
Section 9.1);

     (g) by NeoPath if AutoCyte's Board of Directors (i) fails to include in the
Proxy Statement its recommendation that AutoCyte stockholders vote in favor of
the adoption of this Agreement or (ii) withdraws its recommendation that
stockholders vote in favor (other than in connection with exercising AutoCyte
rights to terminate this Agreement pursuant to Subsection (b) or (d) of this
Section 9.1);

     (h) at any time with the written consent of AutoCyte and NeoPath duly
authorized by their respective Boards of Directors;

     (i) by AutoCyte, if there shall have occurred any event or condition that
constitutes a NeoPath Material Adverse Effect since the date of this Agreement,
which condition or event shall not have been ameliorated such that it is no
longer a NeoPath Material Adverse Effect within ten (10) business days following
receipt by NeoPath of notice from AutoCyte;

     (j) by NeoPath, if there shall have occurred any event or condition that
constitutes an AutoCyte Material Adverse Effect since the date of this
Agreement, which condition or event shall not have been ameliorated such that it
is no longer an AutoCyte Material Adverse Effect within ten (10) business days
following receipt by AutoCyte of notice from NeoPath;

     (k) by AutoCyte or NeoPath, in the event that it receives written notice
from either Ernst & Young LLP or the SEC that, in the opinion of the entity
giving such notice, the Merger will not qualify for pooling of interests
accounting treatment;

     (l) by NeoPath, if the Board of Directors of NeoPath shall have, pursuant
to Section 4.5, recommended or resolved to recommend to the shareholders of
NeoPath a proposal for an Alternative Transaction (as defined in Section 8.3(d))
under circumstances where the Board of Directors determines in good faith (after
consultation with legal counsel, which may be NeoPath's regular outside counsel)
that acceptance of such proposal is necessary for such Board to comply with its
fiduciary duties to its stockholders under applicable law, but only after the
third business day following AutoCyte's receipt of written notice advising
AutoCyte that such Board is prepared to accept a proposal for an Alternative
Transaction and identifying the terms of the Alternative Transaction and the
Person making the proposal for an Alternative Transaction and NeoPath makes the
payment required pursuant to Section 8.3 of this Agreement; and

     (m) by AutoCyte, if the Board of Directors of AutoCyte shall have, pursuant
to Section 4.5, recommended or resolved to recommend to the shareholders of
AutoCyte a proposal for an Alternative Transaction (as defined in Section
8.3(d)) under circumstances where the Board of Directors determines in good
faith (after consultation with legal counsel, which may be AutoCyte's regular
outside counsel) that acceptance of such proposal is necessary for such Board to
comply with its fiduciary duties to its stockholders under applicable law, but
only after the third business day following NeoPath's receipt of written notice
advising NeoPath that such Board is prepared to accept a proposal for an
Alternative Transaction and identifying the terms of the Alternative Transaction
and the Person making the proposal for an Alternative Transaction and AutoCyte
makes the payment required pursuant to Section 8.3 of this Agreement.

     8.2  Notice of Termination; Effect of Termination.  If this Agreement is
terminated as provided in Section 8.1, this Agreement shall forthwith become
void and have no effect, without further obligation on the part of any party,
its directors, officers or stockholders following the date of such termination
other than the provisions of this Section 8.2, Section 8.3 and Section 9
(Miscellaneous); provided, however, that nothing



                                       35
<PAGE>   41

herein shall relieve any party from liability for the willful and material
breach of any of its representations, warranties, covenants or agreements set
forth in this Agreement; provided further, however, that if either party has
received the fee contemplated by Section 8.3(b) or (c), the party receiving such
fee shall not assert or pursue in any manner, directly or indirectly, any claim
or cause of action against the party paying such fee or any of its officers or
directors based in whole or in part upon its or their receipt, consideration,
recommendation or approval of a proposal for a Alternative Transaction or the
exercise of the right of the party paying such fee to terminate this Agreement.
No termination of this Agreement shall affect the obligations of the parties
contained in the Confidentiality Agreement, all of which obligations shall
survive termination of this Agreement in accordance with their terms.

     8.3  Fees and Expenses.

     (a) Except as set forth in this Section 8.3, all fees and expenses incurred
in connection with this Agreement and the transactions contemplated hereby shall
be paid by the party incurring such expenses, whether or not the Merger is
consummated; provided, however, that AutoCyte and NeoPath shall share equally
all fees and expenses, other than attorneys' and accountants fees and expenses,
incurred in relation to the printing and filing of the Proxy Statement
(including any preliminary materials related thereto) and the Registration
Statement (including financial statements and exhibits) and any amendments or
supplements thereto. Notwithstanding the foregoing, in order to induce the other
party to enter into this Agreement and to reimburse the other party for its
costs and expenses and loss of other opportunities related to negotiating and
entering into this Agreement and investigating the desirability of and seeking
to consummate the transactions contemplated by this Agreement, AutoCyte and
NeoPath agree to make cash payments to each other in the circumstances, and in
the amounts, set forth in Sections 8.3(b) and (c).

     (b) NeoPath shall pay AutoCyte a termination fee in an amount equal to the
sum of (x) two million eight hundred thousand dollars ($2,800,000) and (y) all
of AutoCyte's fees and expenses reasonably incurred in connection with this
Agreement and the transactions contemplated hereby, upon the earliest to occur
of the following events:

          (i) the termination of this Agreement by NeoPath pursuant to Section
     8.1(l);

          (ii) the termination of this Agreement by AutoCyte pursuant to Section
     8.1(e) (but only if the AutoCyte stockholders shall have approved the
     Merger as required by the DGCL and the WBCA) as a result of the failure to
     receive the requisite vote for approval of this Agreement and the Merger by
     the stockholders of NeoPath at the NeoPath stockholders' meeting if, at the
     time of such failure,

             (A) there shall have been announced or commenced an Alternative
        Transaction (as defined in Section 8.3(d)) and NeoPath shall have either
        (x) executed an agreement to engage in the same or (y) the NeoPath Board
        of Directors shall not have recommended against such Alternative
        Transaction affirmatively or, if the NeoPath Board of Directors has
        recommended against such Alternative Transaction, the NeoPath Board of
        Directors shall have withdrawn such recommendation against such
        Alternative Transaction or modified such recommendation in a manner
        adverse to AutoCyte, or

             (B) there shall have been announced or commenced an Alternative
        Transaction (as defined in Section 8.3(d)) and (x) NeoPath shall have
        engaged in, or entered into an agreement to engage in, an Alternative
        Transaction with such Third Party or any affiliate thereof within twelve
        months after the date of the NeoPath stockholders' meeting or (y) the
        NeoPath Board of Directors shall have recommended an Alternative
        Transaction with the Third Party proposing such Alternative Transaction
        or any affiliate thereof within twelve months after the date of the
        NeoPath stockholders' meeting; or

          (iii) the termination of this Agreement by AutoCyte pursuant to
     Section 8.1(f) if before such termination or within twelve months
     thereafter NeoPath shall have entered into an agreement to engage in or
     shall have engaged in an Alternative Transaction.

The expenses and fees, if applicable, payable pursuant to this Section 8.3(b)
shall be paid within five business days after the first to occur of the events
described in clauses (ii) or (iii) and prior to the exercise by NeoPath of its
rights as described in clause (i); provided that, (I) despite the foregoing
provision, if NeoPath is obligated to pay a



                                       36
<PAGE>   42

termination fee to AutoCyte pursuant to Section 8.3(b)(ii)(B) or 8.3(b)(iii),
then the fees payable by NeoPath to AutoCyte pursuant to Section 8.3(b)(ii) or
8.3(b)(iii) shall be paid within five business days after the occurrence of the
transaction or recommendation occurring or continuing after the NeoPath
stockholders' meeting which gives rise to the rights to receive the termination
fee and (II) in no event shall NeoPath be required to pay any expenses or
termination fees to AutoCyte if, immediately prior to the termination of this
Agreement, AutoCyte was in breach of any of its material obligations under this
Agreement.

     (c) AutoCyte shall pay NeoPath a termination fee in an amount equal to the
sum of (x) two million eight hundred thousand dollars ($2,800,000) and (y) all
of NeoPath's fees and expenses reasonably incurred in connection with this
Agreement and the transactions contemplated hereby, upon the earliest to occur
of the following events:

          (i) the termination of this Agreement by AutoCyte pursuant to Section
     8.1(m);

          (ii) the termination of this Agreement by NeoPath pursuant to Section
     8.1(e) (but only if the NeoPath stockholders shall have approved the Merger
     as required by the DGCL and the WBCA) as a result of the failure to receive
     the requisite vote for approval of this Agreement and the Merger by the
     stockholders of AutoCyte at the AutoCyte stockholders' meeting if, at the
     time of such failure,

             (A) there shall have been announced or commenced an Alternative
          Transaction (as defined in Section 8.3(d)) and AutoCyte shall have
          either (x) executed an agreement to engage in the same or (y) the
          AutoCyte Board of Directors shall not have recommended against such
          Alternative Transaction affirmatively or, if the AutoCyte Board of
          Directors has recommended against such Alternative Transaction, the
          AutoCyte Board of Directors shall have withdrawn such recommendation
          against such Alternative Transaction or modified such recommendation
          in a manner adverse to NeoPath, or

             (B) there shall have been announced or commenced an Alternative
          Transaction (as defined in Section 8.3(d)) and (x) AutoCyte shall have
          engaged in, or entered into an agreement to engage in, an Alternative
          Transaction with such Third Party or any affiliate thereof within
          twelve months after the date of the AutoCyte stockholders' meeting or
          (y) the AutoCyte Board of Directors shall have recommended an
          Alternative Transaction with the Third Party proposing such
          Alternative Transaction or any affiliate thereof within twelve months
          after the date of the AutoCyte stockholders' meeting; or

          (iii) the termination of this Agreement by NeoPath pursuant to Section
     8.1(g) if before such termination or within twelve months thereafter
     AutoCyte shall have entered into an agreement to engage in or shall have
     engaged in an Alternative Transaction.

The expenses and fees, if applicable, payable pursuant to this Section 8.3(c)
shall be paid within five business days after the first to occur of the events
described in clauses (ii) or (iii) and prior to the exercise by AutoCyte of its
rights as described in clause (i); provided that, (I) despite the foregoing
provision, if AutoCyte is obligated to pay a termination fee to NeoPath pursuant
to Section 8.3(b)(ii)(B) or 8.3(b)(iii), then the fees payable by AutoCyte to
NeoPath pursuant to Section 8.3(b)(ii) or 8.3(b)(iii) shall be paid within five
business days after the occurrence of the transaction or recommendation
occurring or continuing after the AutoCyte stockholders' meeting which gives
rise to the rights to receive the termination fee and (II) in no event shall
AutoCyte be required to pay any expenses or termination fees to NeoPath if,
immediately prior to the termination of this Agreement, NeoPath was in breach of
any of its material obligations under this Agreement.

     (d) As used in this Agreement, "Alternative Transaction" means either (i) a
transaction pursuant to which any person (or group of persons) other than
AutoCyte or NeoPath, or either of their respective affiliates (a "Third Party"),
acquires more than 15% of the outstanding shares of AutoCyte Common Stock or
NeoPath Common Stock, as applicable, pursuant to a tender offer or exchange
offer of otherwise, (ii) a merger or other business combination involving either
AutoCyte or NeoPath, as applicable, pursuant to which any Third Party acquires
more than 15% of the outstanding equity securities of AutoCyte or NeoPath, as
applicable, or the entity surviving such merger or business combination, (iii)
any other transaction pursuant to which any Third Party acquires control of
assets of AutoCyte or NeoPath having a fair market value (as determined by the
Board of Directors of AutoCyte or NeoPath, as applicable, in good faith) equal
to more
                                       37
<PAGE>   43

than 15% of the fair market value of all the assets of AutoCyte or NeoPath, as
applicable, immediately prior to such transaction ("Material Assets"), or (iv)
any public announcement of a proposal, plan or intention to do any of the
foregoing or any agreement to engage in any of the foregoing.

                           SECTION 9 -- MISCELLANEOUS

     9.1  Notices.  Any notice or other communication required or permitted
hereunder shall be in writing and shall be deemed given when so delivered in
person, by overnight courier, by facsimile transmission (with receipt confirmed
by telephone or by automatic transmission report) or two business days after
being sent by registered or certified mail (postage prepaid, return receipt
requested), as follows:

     (a)  if to AutoCyte or Merger Sub, to:

          AutoCyte, Inc.
          780 Plantation Drive
          Burlington, NC 27215
          Attention: President
          Tel: (336) 222-9707
          Fax: (336) 513-0411

     with a copy to:

          Palmer & Dodge LLP
          One Beacon Street
          Boston, Massachusetts 02108
          Attention: Steven N. Farber
                     Marc A. Rubenstein
          Tel: (617) 573-0100
          Fax: (617) 227-4420

     (b)  if to NeoPath, to:

          NeoPath, Inc.
          8271 154th Avenue NE
          Redmond, WA 98052
          Attention: President
          Tel: (425) 869-7284
          Fax: (425) 556-3064

     with a copy to:

          Perkins & Coie LLP
          1201 Third Avenue, 40th Floor
          Seattle, WA 98101-3099
          Attention: Michael E. Stansbury
          Tel: (206) 583-8888
          Fax: (206) 583-8500

          Any party may by notice given in accordance with this Section 9.1 to
          the other parties designate another address or person for receipt of
          notices hereunder.

     9.2  Amendment.  This Agreement may not be amended except by an instrument
signed by each party hereto.

     9.3  Waiver.  At any time prior to the Effective Time, any party hereto
may, (a) extend the time for the performance of any of the obligations or other
acts of any other party hereto or (b) waive compliance with any of the
agreements of any other party or any conditions to its own obligations, in each
case only to the extent such

                                       38
<PAGE>   44

obligations, agreements and conditions are intended for its benefit; provided
that any such extension or waiver shall be binding upon a party only if such
extension or waiver is set forth in a writing executed by such party.

     9.4  Entire Agreement.  This Agreement contains the entire agreement among
the parties with respect to the Merger and related transactions, and supersedes
all prior agreements, written or oral, with respect thereto, it being understood
that the Confidentiality Agreement shall continue in full force and effect until
the Closing and shall survive any termination of this Agreement.

     9.5  Governing Law.  This Agreement is governed by the laws of the State of
Delaware without regard to its conflict of law provisions.

     9.6  Binding Effect; No Assignment.  This Agreement shall be binding upon
and inure to the benefit of the parties and their respective successors and
permitted assigns.

     9.7  Variations in Pronouns.  All pronouns and any variations thereof refer
to the masculine, feminine or neuter, singular or plural, as the context may
require.

     9.8  Counterparts.  This Agreement may be executed in two or more
counterparts, each of which shall be deemed an original, and all of which
together shall constitute one and the same instrument.

     9.9  Exhibits and Disclosure Schedules.  The Exhibits and Disclosure
Schedules are a part of this Agreement as if fully set forth herein.

     IN WITNESS WHEREOF, the parties have executed this Agreement under seal as
of the date first stated above.

                                            AUTOCYTE, INC.

                                            By /s/ James B. Powell
                                               ---------------------------------
                                            Name: James B. Powell
                                            Title: President and Chief Executive
                                            Officer

                                            NEOPATH, INC.

                                            By /s/ Alan C. Nelson
                                               ---------------------------------
                                            Name: Alan C. Nelson
                                            Title: Chairman

                                            TRILOGY ACQUISITION CORPORATION

                                            By /s/ James B. Powell
                                               ---------------------------------
                                            Name: James B. Powell
                                            Title: President

                                       39

<PAGE>   1

                                                                    EXHIBIT 99.1
                                                                    ------------

CONTACTS:

                  William O. Green, Chief Financial Officer, AutoCyte, Inc.
                  (336) 222-9707

                  Robert C. Bateman, Chief Financial Officer, NeoPath, Inc.
                  (425) 556-4699, [email protected]


AUTOCYTE AND NEOPATH AGREE TO MERGE

COMBINATION CREATES COMPREHENSIVE PRODUCT OFFERING FOR THE CLINICAL LABORATORY

BURLINGTON, NC, and REDMOND, WA, June 7, 1999 - AutoCyte, Inc. (NASDAQ: ACYT)
and NeoPath, Inc. (NASDAQ: NPTH) today announced that they have entered into a
definitive agreement to merge the two companies in a tax-free stock exchange.
NeoPath's shareholders will receive .7903 shares of AutoCyte common stock in
exchange for each share of NeoPath common stock in a transaction that is
expected to be accounted for as a pooling of interests. The new company will be
headquartered in Burlington, NC.

Dr. James B. Powell, AutoCyte's President and Chief Executive Officer, and
President and CEO of the merged companies, stated, "This is a very exciting day
for both of our companies, our shareholders, our customers, and women's
healthcare. We believe the merger of AutoCyte and NeoPath will provide the
definitive integrated cervical cytology system to clinical laboratories, and
that, together, our combined sample preparation and computerized screening
products should allow us to offer our customers an entire range of cervical
cytology screening choices."

Dr. Powell continued, "The merged companies will offer liquid-based thin-layer
slide preparation technology with the AutoCyte PREP System(TM) ("PREP"). We will
also offer NeoPath's AutoPap(R) Primary Screening System ("AutoPap"), which is
the only FDA-approved device for automated primary screening of conventional Pap
smears. Also, as previously announced, AutoCyte and NeoPath are currently
conducting a joint clinical trial for the screening of PREP slides by AutoPap.
This supplement is expected to be submitted to the FDA in the second half of
1999. Finally, our recent purchase of the Neuromedical Systems, Inc.
intellectual property could allow us to further enhance our future product
offerings. The combination of thin-layer slide preparation technology and
automated primary screening of both thin-layer and conventional Pap smears is
expected to create a unique, comprehensive and cost-effective product offering
for our clinical laboratory customers."

Dr. Alan C. Nelson, Chairman of NeoPath and the merged companies, stated "The
combination of AutoCyte and NeoPath creates a strong, dynamic force in improving
cervical cancer screening by addressing both sample preparation and computerized
screening. By combining our individual strengths in sales, customer service and
product development, we will be able to offer a compelling solution for cancer
screening at large clinical labs, at a price that is expected to accelerate
market conversion to these breakthrough technologies. We believe that the
combined companies will also realize significant operational efficiencies
through the consolidation of research and development, administration, sales and
marketing, reimbursement, and regulatory efforts. In anticipation of these
operational efficiencies, NeoPath will immediately reduce its workforce by
one-third and will have approximately 100 continuing employees."


<PAGE>   2

                                       2

The transaction is expected to be completed within six months, pending
shareholder and regulatory approval.

AutoCyte develops, manufactures and markets the AutoCyte PREP System(TM), a
proprietary automated liquid-based cytology sample preparation system that
produces representative slides with a homogeneous, thin-layer of cervical cells.
AutoCyte is currently pursuing regulatory approval of PREP for sale in the
United States and has begun sales in several foreign countries. AutoCyte
announced on March 22 that it has been notified that FDA has completed
successful review of the clinical data in the PREP PMA application and is
currently awaiting completion of the final labeling review and approval process.

NeoPath provides visual intelligence technology to increase accuracy and
productivity in medical testing. The AutoPap(R) Primary Screening System
utilizes proprietary visual intelligence technology to distinguish between
normal Pap smears and those that have the highest likelihood of abnormality. In
May 1998, the AutoPap System was approved by the U.S. Food and Drug
Administration as the first fully automated device for primary screening of Pap
smear slides. NeoPath's core expertise is in the research, development and
commercialization of imaging technologies to improve disease diagnosis and
healthcare cost-effectiveness.

More information may be found at AutoCyte's homepage: HTTP://WWW.AUTOCYTE.COM
and NeoPath's homepage: HTTP://WWW.NEOPATH.COM.

Forward-looking statements in this release are made pursuant to the safe harbor
provisions of the Private Securities Litigation Reform Act of 1995. These
forward-looking statements are subject to various risks and uncertainties,
including without limitation, product and manufacturing regulatory approvals;
the Companies' limited manufacturing, marketing, customer service and support
capabilities; the status of competing products and associated litigation; and
other risks and uncertainties detailed in the Companies' filings with the
Securities and Exchange Commission.
                                     # # # #


<PAGE>   1

                                                                    EXHIBIT 99.2
                                                                    ------------


FOR IMMEDIATE RELEASE
- ---------------------

AUTOCYTE PREP SYSTEM(TM) APPROVED BY FDA

Burlington, N.C., June 18 -- AutoCyte, Inc. (Nasdaq: ACYT) today announced that
the United States Food & Drug Administration ("FDA") has approved the AutoCyte
PREP System(TM) ("PREP") for use in primary screening for cervical cancer. PREP
is AutoCyte's liquid-based thin-layer sample preparation system that
automatically prepares and stains cytology slides. PREP is designed to replace
the conventional Pap smear with a preparation that is cleaner, more uniform and
easier to interpret.

Dr. James B. Powell, AutoCyte's President and Chief Executive Officer, stated,
"This FDA clearance is a significant milestone both for AutoCyte and for women's
healthcare. Numerous studies have shown that PREP offers several advantages over
the conventional Pap smear process, including improved sample quality, greater
consistency and improved laboratory productivity."

Dr. Powell went on to state, "AutoCyte is prepared for the full-scale
commercialization of PREP. We will immediately commence our product rollout
strategy. First, we will focus on executing cervical cytology contracts with our
existing installed base of customers currently using PREP for non-cervical
cytology. Among these customers are some of the largest clinical laboratories in
the U.S. Second, we will continue to pursue our strategy of being the low-cost,
high-throughput alternative to the conventional Pap smear by promoting the
advantages of this valuable technology. Our PREP system should be particularly
valuable to high-volume laboratories who benefit most from automation
encompassing both slide preparation and staining."

In conclusion, Dr. Powell stated, "We expect the remainder of 1999 to be a very
exciting and very successful time for AutoCyte as we achieve our goal of
commercialization of PREP for cervical cancer screening. We appreciate the
support of our investors, customers, suppliers and employees in helping us
achieve this goal."

AutoCyte develops, manufactures and markets the AutoCyte PREP System(TM), a
proprietary automated liquid-based cytology sample preparation system that
produces representative slides with a homogeneous, thin-layer of cervical cells.
AutoCyte announced on June 7 that it has entered into a definitive agreement to
merge with NeoPath, Inc. (NASDAQ: NPTH) in a tax-free stock exchange. NeoPath's
shareholders will receive .7903 shares of AutoCyte common stock in exchange for
each share of NeoPath common stock in a transaction that is expected to be
accounted for as a pooling of interests. The new company will be headquartered
in Burlington, NC. The transaction is expected to be completed within six
months, pending shareholder and regulatory approval. AutoCyte and NeoPath are
currently conducting a joint clinical trial for the screening of PREP slides by
NeoPath's AutoPap(R) Primary Screening System. This supplement is expected to be
submitted to the FDA in the second half of 1999.

Forward-looking statements in this release are made pursuant to the safe harbor
provisions of the Private Securities Litigation Reform Act of 1995. Investors
are cautioned that statements in this press release which are not strictly
historical statements constitute forward-looking statements which involve risks
and uncertainties including, without limitation, risks associated with
uncertainties regarding FDA approval, uncertainties regarding market acceptance
and additional cost, risks associated with technological change, the Company's
history of operating losses and the uncertainty of future profitability,
dependence on a limited number of products, dependence on third-party
reimbursement, limited marketing and sales experience, limited number of
customers and lengthy sales cycle, risks of adverse changes in general economic
conditions, and in the






<PAGE>   2

healthcare industry specific risks associated with competition and competitive
pricing pressures, and other risks detailed in the Company's filings with the
Securities and Exchange Commission.

Contact: Dr. James B. Powell, President and Chief Executive Officer, or William
O. Green, Chief Financial Officer, AutoCyte, Inc., 800-426-2176

NOTE TO INVESTORS AND EDITORS: AutoCyte's press releases are available on the
Internet through PR Newswire's web site at http://www.prnewswire.com. The
releases are also available at no charge through PR Newswire's Company News
On-Call fax service at 800-758-5804, extension 116041.


                                       2




© 2022 IncJournal is not affiliated with or endorsed by the U.S. Securities and Exchange Commission