ISI STRATEGY FUND INC
24F-2NT, 1998-08-24
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                             Form 24F-2

      Annual Notice of Securities Sold Pursuant to Rule 24F-2

                           UNITED STATES
                 SECURITIES AND EXCHANGE COMMISSION
                      Washington, D.C.  20549

                             FORM 24F-2
                  Annual Notice of Securities Sold
                       Pursuant to Rule 24f-2

     Read instructions at end of Form before preparing Form.  

1.   Name and address of issuer:   ISI Strategy Fund, Inc.
                         One South Street, Baltimore, MD 21202

2.   The name of each series or class of securities for which this
     Form is filed.  (If the Form is being filed for all series and
     classes of securities of the issuer, check the box but do not
     list series or classes):      [X]

3.   Investment Company Act File Number:     811-8291

     Securities Act File Number:   333-31127


4(a).     Last day of fiscal year for which this Form is filed: May 31, 1998


4(b).[ ]       Check box if this Form is being filed late (i.e.,
               more than 90 calendar days after the end of the
               issuer's fiscal year).  (See Instruction A.2.)

Note:  If the Form is being filed late, interest must be paid on
the registration fee due.

4(c).[ ]       Check box if this is the last time the issuer will
               be filing this Form.


5.   Calculation of registration fee:

     (i)   Aggregate sale price of securities sold during the
           fiscal year pursuant to section 24(f):            $18,353,067.36
                                                             --------------

     (ii)  Aggregate price of securities redeemed or
           repurchased during the fiscal year:     $1,044,831.00
                                                  --------------

     (iii) Aggregate price of securities redeemed or 
           repurchased during any prior fiscal year ending 
           no earlier than October 11, 1995 that were not
<PAGE>




          previously used to reduce registration fees
          payable to the Commission:             $          0.00
                                                  --------------

     (iv) Total available redemption credits 
          {add Items 5(ii) and 5(iii)}:                     -$1,044,831.00
                                                             --------------
     (v)  Net sales -- if Item 5(i) is greater than Item 5(iv)
          {subtract Item 5(iv) from Item 5(i)}:             $17,308,236.36
                                                             --------------

     (vi)  Redemption credits available for use  $       (0.00)
           in future years -- if Item 5(i) is    --------------
           less than Item 5(iv)
           {subtract Item 5(iv) from Item 5(i)}:

    (vii) Multiplier for determining registration fee
          (See Instruction C.9):                            x      .000295
                                                             --------------

     (viii)    Registration fee due {multiply Item 5(v) by Item
          5(vii)} (enter "0" if no fee is due):                 =$5,105.93
                                                             --------------
6.   Prepaid Shares

     If the response to Item 5(i) was determined by deducting an
     amount of securities that were registered under the Securities
     Act of 1933 pursuant to rule 24e-2 as in effect before October
     11, 1997, then report the amount of securities (number of
     shares or other units) deducted here: N/A.  If there is a
     number of shares or other units that were registered pursuant
     to rule 24e-2 remaining unsold at the end of the fiscal year
     for which this form is filed that are available for use by the
     issuer in future fiscal years, then state that number here:
     N/A.

7.   Interest due -- if this Form is being filed more than 90 days
     after the end of the issuer's fiscal year (see Instruction D):
                                                              +$     00.00
                                                             --------------

8.   Total of the amount of the registration fee due plus any
     interest due {line 5(viii) plus line 7}:
                                                                =$5,105.93
                                                             --------------

9.   Date the registration fee and any interest payment was sent to
     the Commission's lockbox depository:  8/21/98
          Method of Delivery:
                         [X] Wire Transfer
                         [ ] Mail or other means


                             2 <PAGE> 
<PAGE>
                             SIGNATURES

This report has been signed below by the following person on behalf
of the issuer and in the capacities and on the dates indicated.


By (Signature and Title)*     /s/ Joseph A. Finelli
                              Joseph A. Finelli, Treasurer

   *Please print the name and title of the signing officer below the
signature.

Date: August 24, 1998















































                             3 <PAGE> 
<PAGE>




<TABLE>
                                                                         Schedule A 
                                                                     to 24f-2 Notice of 
                                                                   ISI Strategy Fund, Inc.*
<CAPTION>
<S>            <C>                 <C>             <C>              <C>         <C>          <C>        <C>

                                                                                  Value of                  Cost of 
               Number of Shares      Aggregate     Front-end Sales    Shares     Reinvested   Shares    Shares Redeemed
      Class          Sold           Sales Price         Loads       Reinvested   Dividends   Redeemed

ISI Shares          1,744,374      $18,021,106.00    $232,146.36        9,391   $99,815.00    96,939      $1,044,831.00

<FN>
         Computation of Fee:      $18,021,106.00 + $99,815.00 + $232,146.36 = $18,353,067.36
                                  $18,353,067.36 - $1,044,831.00 = $17,308,236.36
                                  $17,308,236.36 x .000295 = $5,105.93



* The Fund commenced operations on September 16, 1997.  
	                     4 <PAGE> 
</FN>
</TABLE>
<PAGE>


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