CORIXA CORP
S-4/A, EX-8.2, 2000-11-17
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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               [LETTERHEAD OF ORRICK, HERRINGTON & SUTCLIFFE LLP]


                                November 17, 2000



Board of Directors
Corixa Corporation
1124 Columbia Street, Suite 200
Seattle, Washington 98104

Ladies and Gentlemen:

               We have acted as your counsel in connection with the contemplated
merger (the "Merger") of Clearwater Acquisitions Corp. ("Merger Sub"), a
Delaware corporation and wholly-owned subsidiary of Corixa Corporation
("Corixa"), a Delaware corporation, with and into Coulter Pharmaceutical, Inc.
("Coulter"), a Delaware corporation, pursuant to an Agreement and Plan of Merger
dated as of October 15, 2000 (the "Merger Agreement"), by and among Corixa,
Merger Sub and Coulter. All capitalized terms used herein, unless otherwise
specified, have the meanings assigned to them in the Merger Agreement. This
opinion is being delivered to you in connection with a registration statement on
Form S-4 in the form filed with the Securities and Exchange Commission (the
"Registration Statement"), which includes the Proxy Statement and Prospectus
relating to the Merger.

               In rendering our opinion, we have examined and relied upon the
accuracy and completeness of the facts, information, covenants and
representations contained in the Registration Statement, the Merger Agreement
and such other documents and corporate records as we have deemed necessary or
appropriate for purposes of this opinion. In addition, we have relied upon
certain statements, representations and agreements made by Coulter and Corixa,
including representations set forth in the Officer's Certificates of Coulter and
Corixa that were provided to us (the "Officers' Certificates"). Our opinion is
conditioned on, among other things, the initial and continuing accuracy of the
facts, information, covenants and representations set forth in the documents
referred to above and the statements, representations and agreements made by
Coulter, Corixa and others, including those set forth in the Officers'
Certificates. We have no reason to believe that such facts, information,
covenants and representations are not true, but have not attempted to verify
them independently and expressly disclaim an opinion as to their validity and
accuracy.

        In our examination, we have assumed (without any independent
investigation) that:

        1. At all relevant times prior to and including the Effective Time, (i)
no outstanding indebtedness of Corixa, Coulter, or Merger Sub has represented or
will represent equity for tax purposes; (ii) no outstanding equity of Corixa,
Coulter, or Merger Sub has represented or will



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Board of Directors
Corixa Corporation
November 17, 2000
Page 2


represent indebtedness for tax purposes; (iii) no outstanding security,
instrument, agreement or arrangement that provides for, contains, or represents
a right either to acquire Coulter's capital stock or to share in the
appreciation thereof constitutes or will constitute "stock" for purposes of
Section 368(c) of the Internal Revenue Code of 1986, as amended (the "Code").

               2. Original documents (including signatures thereto) are
authentic, documents submitted to us as certified or photostatic copies conform
to the original documents, and there has been (or will be by the Effective Time)
due execution and delivery of all documents where due execution and delivery are
prerequisites to the effectiveness thereof.

               3. The transactions related to the Merger or contemplated by the
Merger Agreement will be consummated in accordance with such agreements and all
covenants contained in the Merger Agreement (including exhibits thereto) and the
Officers' Certificates will be performed without waiver or breach of any
material provision thereof.

               4. Any representation or statement made "to the best of
knowledge" or similarly qualified is correct without such qualification.

               5. The Merger qualifies as a statutory merger under the laws of
the State of Delaware.

               6. The Merger Agreement and all other documents and instruments
referred to in the Registration Statement are valid and binding in accordance
with their terms.

               The opinion expressed in this letter is based on the provisions
of the Code, Treasury regulations promulgated thereunder, and administrative and
judicial interpretations thereof, all as in effect as of the date hereof. All of
the foregoing are subject to change, perhaps with retroactive effect; any such
change may require modification of the opinion rendered herein. No ruling from
the Internal Revenue Service (the "IRS") has been or will be sought on any
aspect of the Merger, and there can be no assurance that the IRS will not take a
contrary view. Although our opinion expressed in this letter represents our best
judgment as to such matters, our opinion has no binding effect on the IRS or the
courts.

               Based upon and subject to the foregoing, and subject to the
qualifications set forth herein, we are of the opinion that (i) the Merger will
constitute a reorganization within the meaning of Section 368(a) of the Code,
and (ii) the discussion under the heading "The Merger -- Material U.S. Federal
Income Tax Consequences," sets forth the material United States federal income
tax consequences generally applicable to the Merger, and, insofar as it relates
to statements of law and legal conclusions, is correct in all material respects.
Because this opinion is being delivered prior to the Effective Time of the
Merger, it must be considered prospective and dependent on future events. There
can be no assurance that changes in the law will not take place that could



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Board of Directors
Corixa Corporation
November 17, 2000
Page 3


affect the United States federal income tax consequences of the Merger or that
contrary positions may not be taken by the IRS.

               We express no opinions as to matters of law other than the
matters of federal income tax law specifically addressed hereby. We are
furnishing this opinion to you solely for the purpose of its inclusion as an
exhibit to the Registration Statement. It may not be relied upon for any other
purpose or by any other person or entity, and may not be made available to any
other person or entity without our prior written consent.

               We hereby consent to the use of our name wherever appearing in
the Registration Statement with respect to the discussion of the material
federal income tax consequences of the Merger and to the filing of this opinion
as an exhibit to the Registration Statement. In giving this consent, we do not
thereby admit that we are in the category of persons whose consent is required
under Section 7 of the Securities Act of 1933, as amended, or the rules and
regulations of the Securities and Exchange Commission thereunder, nor do we
thereby admit that we are experts with respect to any part of such Registration
Statement within the meaning of the term "experts" as used in the Securities Act
of 1933, as amended, or the rules and regulations of the Securities and Exchange
Commission thereunder. We disclaim any obligation to update this opinion letter
for events, including changes of law, that occur or come to our attention after
the date hereof.


                                        Very truly yours,

                                        /s/ Orrick, Herrington & Sutcliffe LLP




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