TRANSGENOMIC INC
S-1, EX-5, 2000-12-15
LABORATORY ANALYTICAL INSTRUMENTS
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                                                                       EXHIBIT 5

                                 Kutak Rock LLP
                               The Omaha Building
                               1650 Farnam Street
                              Omaha, Nebraska 68102
                                  402-346-6000
                            Facsimile (402) 346-1148
                                WWW.KUTAKROCK.COM


                                                December 15, 2000


Transgenomic, Inc.
5600 South 42nd Street
Omaha, NE  68107

     Re: Transgenomic, Inc. Registration Statement on Form S-1 for
         3,050,906 Shares of Common Stock

Ladies and Gentlemen:

     We have acted as counsel for Transgenomic, Inc., a Delaware corporation,
(the "Company"), in connection with the filing of a Registration Statement on
Form S-1 (the "Registration Statement") under the Securities Act of 1933, as
amended, with respect to the registration of 3,050,000 issued and outstanding
shares of common stock of the Company (the "Shares") to be sold from time to
time by certain shareholders of the Company.

     This opinion is being furnished in accordance with the requirements of Item
16(a) of Form S-1 and Item 601(b)(5)(i) of Regulation S-K.

     In the course of such representation, we have examined, among other things,
such corporate records, certificates of public officials and other documents we
deemed relevant and appropriate.

     Based on the foregoing, we are of the opinion that the Shares have been
legally issued and are fully paid and nonassessable.

     We hereby consent to the filing of this opinion letter as an exhibit to the
Registration Statement and to the reference to this firm under the heading
"Legal Matters" in the prospectus which is part of the Registration Statement.
In giving this consent, we do not thereby admit that we are within the category
of persons whose consent is required under Section 7 of the Act, the rules and
regulations of the Securities and Exchange Commission promulgated thereunder, or
Item 509 of Regulation S-K.

     This opinion letter is rendered as of the date first written above and we
disclaim any obligation to advise you of facts, circumstances, events or
developments which hereafter may be



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Transgenomic, Inc.
December 15, 2000
Page 2



brought to our attention and which may alter, affect or modify the opinion
expressed herein. Our opinion is expressly limited to the matters set forth
above and we render no opinion, whether by implication or otherwise, as to any
other matters relating to the Company or the Shares.

                                         Very truly yours,




                                         /s/ Kutak Rock LLP



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