AGRITOPE INC
8-K, EX-99.1, 2000-09-14
COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
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                            FORM OF VOTING AGREEMENT


      THIS VOTING  AGREEMENT is entered  into as of  September  7, 2000,  by and
between  EXELIXIS,  INC.,  a  Delaware  corporation  ("Parent"),  and
                                                                      ----------
("Stockholder").

                                    RECITALS

      A.    Parent,  Athens  Acquisition  Corp.,  a Delaware  corporation  and a
wholly owned subsidiary of Parent ("Merger Sub"), and Agritope, Inc., a Delaware
corporation (the  "Company"),  are entering into an Agreement and Plan of Merger
and Reorganization of even date herewith (the "Reorganization  Agreement") which
provides  (subject to the conditions set forth therein) for the merger of Merger
Sub into the Company (the "Merger").

      B.    In  order  to  induce  Parent  and  Merger  Sub to  enter  into  the
Reorganization Agreement, Stockholder is entering into this Voting Agreement.

                                    AGREEMENT

      The parties to this Voting Agreement, intending to be legally bound, agree
as follows:

SECTION  1. CERTAIN DEFINITIONS

            For purposes of this Voting Agreement:

            (A)   "COMPANY CAPITAL  STOCK" shall mean, collectively, the Company
Common Stock and the Company Series A Preferred Stock.

            (B) "COMPANY  COMMON  STOCK" shall mean the common  stock,  $.01 par
value per share, of the Company.

            (C)  "COMPANY  SERIES A  PREFERRED  STOCK"  shall  mean the Series A
Preferred Stock, $.01 par value per share, of the Company.

            (D)  "EXPIRATION  DATE"  shall mean the earlier of (i) the date upon
which the Reorganization Agreement is validly terminated,  or (ii) the date upon
which the Merger becomes effective.

            (E)  Stockholder  shall  be  deemed  to  "OWN"  or to have  acquired
"OWNERSHIP"  of a  security  if  Stockholder:  (i) is the  record  owner of such
security;  or (ii) is the  "beneficial  owner" (within the meaning of Rule 13d-3
under the Securities Exchange Act of 1934) of such security.

            (F)  "PERSON"  shall  mean  any (i)  individual,  (ii)  corporation,
limited liability  company,  partnership or other entity, or (iii)  governmental
authority.




                                       1
<PAGE>


            (G)  "SUBJECT  SECURITIES"  shall mean:  (i) all  securities  of the
Company  (including  all  shares  of  Company  Capital  Stock  and all  options,
warrants,  convertible  notes and  other  rights to  acquire  shares of  Company
Capital Stock) Owned by Stockholder as of the date of this  Agreement;  and (ii)
all additional  securities of the Company  (including  all additional  shares of
Company Capital Stock and all additional  options,  warrants,  convertible notes
and  other  rights  to  acquire  shares  of  Company  Capital  Stock)  of  which
Stockholder acquires Ownership during the period from the date of this Agreement
through the Expiration Date.

            (H) A Person  shall be deemed to have a effected a  "TRANSFER"  of a
security if such Person directly or indirectly:  (i) sells, pledges,  encumbers,
grants an option with respect to,  transfers or disposes of such security or any
interest  in such  security;  or (ii)  enters into an  agreement  or  commitment
contemplating  the  possible  sale of,  pledge of,  encumbrance  of, grant of an
option with  respect  to,  transfer of or  disposition  of such  security or any
interest therein.


SECTION 2.  TRANSFER OF SUBJECT SECURITIES

      2.1   TRANSFEREE  OF  SUBJECT  SECURITIES  TO BE BOUND BY THIS  AGREEMENT.
Stockholder  agrees  that,  during  the  period  from  the  date of this  Voting
Agreement through the Expiration Date, Stockholder shall not cause or permit any
Transfer of any of the Subject  Securities to be effected  unless each Person to
which any of such  Subject  Securities,  or any  interest in any of such Subject
Securities,  is or may be transferred  shall have: (a) executed a counterpart of
this Voting Agreement and a proxy in the form attached hereto as Exhibit A (with
such  modifications  as Parent may reasonably  request);  and (b) agreed to hold
such Subject Securities (or interest in such Subject  Securities) subject to all
of the terms and provisions of this Voting Agreement.

      2.2   TRANSFER  OF VOTING  RIGHTS.  Stockholder  agrees  that,  during the
period  from the date of this Voting  Agreement  through  the  Expiration  Date,
Stockholder  shall ensure that: (a) none of the Subject  Securities is deposited
into a voting  trust;  and (b) no proxy is granted,  and no voting  agreement or
similar  agreement  is  entered  into,  with  respect  to  any  of  the  Subject
Securities.

      2.3   MARGIN ACCOUNTS. In the event that any of the Subject Securities are
held in a margin  account  with a  broker-dealer  as of the date of this  Voting
Agreement,  Stockholder  agrees  that,  during the period  from the date of this
Voting  Agreement  through the  Expiration  Date, if there is a margin call with
respect  to such  margin  account,  Stockholder  shall  ensure  that  sufficient
collateral is deposited into such margin account so that the Subject  Securities
are not sold or otherwise transferred.

SECTION 3.  VOTING OF SHARES

      3.1   VOTING  AGREEMENT.  Stockholder  agrees that, during the period from
the date of this Voting Agreement through the Expiration Date, at any meeting of
stockholders  of the  Company,  however  called,  and in any  written  action by
consent of  stockholders  of the Company,  Stockholder  shall (unless  otherwise
directed in writing by Parent) cause all outstanding shares of




                                       2
<PAGE>


Company Capital Stock that are Owned by Stockholder as of the record date  fixed
for such meeting or written consent:

            (A) to be  voted  in  favor  of the  approval  and  adoption  of the
Reorganization Agreement and the approval of the Merger on the terms and subject
to the conditions  set forth therein,  and in favor of each of the other actions
contemplated by the Reorganization Agreement;

            (B) to be voted  against any action or agreement  that to the actual
knowledge  of  Stockholder  would result in a material  breach of any  covenant,
representation  or warranty or any other  obligation or agreement of the Company
under the Reorganization Agreement; and

            (C) to be voted against the following actions (other than the Merger
and the  transactions  contemplated by the  Reorganization  Agreement):  (A) any
extraordinary  corporate transaction,  such as a merger,  consolidation or other
business combination involving the Company or any subsidiary of the Company; (B)
a sale,  lease or transfer of a material  amount of assets of the Company or any
subsidiary of the Company or a reorganization,  recapitalization, dissolution or
liquidation  of the Company or any  subsidiary  of the  Company;  or (C) (1) any
change in a majority of the board of directors of the Company; (2) any amendment
of the Company's Certificate of Incorporation;  (3) any other material change in
the present  capitalization  of the Company or any  amendment  of the  Company's
corporate  structure;  or (4) any other action which to the actual  knowledge of
Stockholder is intended,  or could  reasonably be expected to impede,  interfere
with, delay, postpone,  discourage or adversely affect the contemplated economic
benefits to Parent of the Merger or any of the other  transactions  contemplated
by the Reorganization Agreement or this Voting Agreement.

Stockholder shall not enter into any agreement or understanding  with any Person
prior to the  earlier to occur of the valid  termination  of the  Reorganization
Agreement  or the  Effective  Time to vote or give  instructions  in any  manner
inconsistent with clause "(a)," "(b)" or "(c)" of the preceding sentence.


      3.2   PROXY.   Contemporaneously   with  the   execution  of  this  Voting
Agreement:  (i) Stockholder shall deliver to Parent a proxy in the form attached
to this Voting Agreement as Exhibit A, which shall be irrevocable to the fullest
extent  permitted by law,  with  respect to the shares  referred to therein (the
"Proxy");  and (ii) except as set forth on any Schedule 3.2 hereto,  Stockholder
shall cause to be delivered to Parent an additional  proxy (in the form attached
hereto as EXHIBIT A) executed on behalf of the record  owner of any  outstanding
shares of Company Capital Stock that are owned beneficially  (within the meaning
of Rule 13d-3 under the Securities  Exchange Act of 1934), but not of record, by
Stockholder.


SECTION 4.  WAIVER OF APPRAISAL RIGHTS

      Stockholder hereby irrevocably and  unconditionally  waives, and agrees to
cause to be waived and to prevent the exercise of, any rights of appraisal,  any
dissenters'  rights and any similar rights relating to the Merger or any related
transaction  that  Stockholder  or any  other




                                       3
<PAGE>


Person  may  have  by virtue of the ownership  of  any  outstanding   shares  of
Company  Capital  Stock  Owned  by Stockholder.

SECTION 5.  NO SOLICITATION

      Stockholder  agrees in his or her capacity as such that, during the period
from the date of this Voting Agreement through the Expiration Date,  Stockholder
shall not,  directly  or  indirectly,  and  Stockholder  shall  ensure  that his
Representatives (as defined in the Reorganization Agreement) do not, directly or
indirectly: (i) solicit, initiate, encourage or induce the making, submission or
announcement  of any  Acquisition  Proposal  (as  defined in the  Reorganization
Agreement)  or take any action that could  reasonably  be expected to lead to an
Acquisition Proposal;  (ii) furnish any information regarding the Company or any
direct or indirect subsidiary of the Company to any Person in connection with or
in response to an Acquisition  Proposal or potential  Acquisition  Proposal;  or
(iii)  engage in  discussions  with any Person with  respect to any  Acquisition
Proposal.  Stockholder shall immediately cease and discontinue,  and Stockholder
shall ensure that his  Representatives  immediately  cease and discontinue,  any
existing discussions with any Person that relate to any Acquisition Proposal.


SECTION 6.  REPRESENTATIONS AND WARRANTIES OF STOCKHOLDER

      Stockholder hereby represents and warrants to Parent as follows:

      6.1   AUTHORIZATION,  ETC.  Stockholder has the absolute and  unrestricted
right,  power,  authority  and  capacity  to execute  and  deliver  this  Voting
Agreement and the Proxy and to perform his obligations hereunder and thereunder.
This Voting  Agreement  and the Proxy have been duly  executed and  delivered by
Stockholder and constitute legal, valid and binding  obligations of Stockholder,
enforceable against  Stockholder in accordance with their terms,  subject to (i)
laws of general application relating to bankruptcy, insolvency and the relief of
debtors and (ii) rules of law governing specific performance,  injunctive relief
and other equitable remedies.

      6.2   NO  CONFLICTS OR CONSENTS

            (A) The  execution  and  delivery of this Voting  Agreement  and the
Proxy by  Stockholder do not, and the  performance of this Voting  Agreement and
the Proxy by  Stockholder  will not: (i) conflict with or violate any law, rule,
regulation,  order,  decree or judgment applicable to Stockholder or by which he
or any of his  properties  is or may be bound or affected;  or (ii) result in or
constitute  (with or  without  notice or lapse of time) any breach of or default
under, or give to any other Person (with or without notice or lapse of time) any
right of termination,  amendment,  acceleration  or  cancellation  of, or result
(with or without notice or lapse of time) in the creation of any  encumbrance or
restriction on any of the Subject Securities  pursuant to, any contract to which
Stockholder  is a party  or by which  Stockholder  or any of his  affiliates  or
properties is or may be bound or affected.




                                       4
<PAGE>


            (B) The  execution  and  delivery of this Voting  Agreement  and the
Proxy by  Stockholder do not, and the  performance of this Voting  Agreement and
the Proxy by  Stockholder  will not,  require  any  consent or  approval  of any
Person.

      6.3   TITLE TO SECURITIES.  As of the date of this Voting  Agreement:  (a)
Stockholder  holds of record (free and clear of any encumbrances or restrictions
other than pursuant to standard margin  agreements  between  Stockholder and any
broker-dealer)  the number of  outstanding  shares of Company  Capital Stock set
forth under the heading  "Shares Held of Record" on the  signature  page hereof;
(b) Stockholder holds (free and clear of any encumbrances or restrictions  other
than  pursuant  to  standard  margin  agreements  between  Stockholder  and  any
broker-dealer)  the  options,  warrants  and other  rights to acquire  shares of
Company Capital Stock set forth under the heading  "Options and Other Rights" on
the signature page hereof; (c) Stockholder Owns the additional securities of the
Company set forth under the heading "Additional  Securities  Beneficially Owned"
on the  signature  page  hereof;  and  (d)  Stockholder  does  not  directly  or
indirectly  Own any shares of capital stock or other  securities of the Company,
or any option,  warrant or other right to acquire (by  purchase,  conversion  or
otherwise) any shares of capital stock or other securities of the Company, other
than the  shares  and  options,  warrants  and  other  rights  set  forth on the
signature page hereof.

      6.4   ACCURACY OF  REPRESENTATIONS.  The  representations  and  warranties
contained in this Voting  Agreement  are accurate in all respects as of the date
of this Voting Agreement,  will be accurate in all respects at all times through
the  Expiration  Date and will be accurate in all respects as of the date of the
consummation of the Merger as if made on that date.


SECTION 7.  ADDITIONAL COVENANTS OF STOCKHOLDER

      7.1   FURTHER  ASSURANCES.  From  time  to  time  and  without  additional
consideration,  Stockholder  shall execute and deliver,  or cause to be executed
and delivered, such additional transfers,  assignments,  endorsements,  proxies,
consents and other  instruments,  and take such further  actions,  as Parent may
request for the purpose of carrying out and furthering the intent of this Voting
Agreement.

      7.2   LEGEND.  Immediately  after the  execution of this Voting  Agreement
(and from time to time upon the  acquisition  by Stockholder of Ownership of any
shares of Company Capital Stock prior to the Expiration Date), Stockholder shall
use commercially  reasonable efforts to ensure that each certificate  evidencing
any  outstanding  shares of Company  Capital  Stock or other  securities  of the
Company Owned by Stockholder bears a legend in the following form:

      THE SECURITY OR  SECURITIES  REPRESENTED  BY THIS  CERTIFICATE  MAY NOT BE
      SOLD,  EXCHANGED  OR  OTHERWISE  TRANSFERRED  OR  DISPOSED  OF  EXCEPT  IN
      COMPLIANCE WITH THE TERMS AND PROVISIONS OF THE VOTING  AGREEMENT DATED AS
      OF SEPTEMBER 7, 2000,  BETWEEN THE




                                       5
<PAGE>


      HOLDER AND EXELIXIS, INC. AS IT MAY BE AMENDED, A COPY OF WHICH IS ON FILE
      AT THE PRINCIPAL  EXECUTIVE OFFICES OF THE ISSUER.

SECTION 8.  MISCELLANEOUS

      8.1   SURVIVAL  OF   REPRESENTATIONS,   WARRANTIES  AND  AGREEMENTS.   All
representations,  warranties,  covenants and  agreements  made by Stockholder in
this Voting Agreement shall survive (i) the consummation of the Merger, (ii) any
termination  of the  Reorganization  Agreement  and (iii) the  Expiration  Date,
except that Stockholder  shall not be required to vote shares of Company Capital
Stock pursuant to Section 3.1 hereof from and after the Expiration Date.

      8.2   EXPENSES.  All costs and expenses  incurred in  connection  with the
transactions  contemplated  by this Voting  Agreement shall be paid by the party
incurring such costs and expenses.

      8.3   NOTICES. Any notice or other communication  required or permitted to
be delivered to either party under this Voting Agreement shall be in writing and
shall be deemed properly delivered,  given and received when delivered (by hand,
by registered  mail, by courier or express  delivery service or by facsimile) to
the address or  facsimile  telephone  number set forth  beneath the name of such
party  below (or to such other  address or  facsimile  telephone  number as such
party shall have specified in a written notice given to the other party):

        if to Stockholder:

                  at the address set forth below  Stockholder's signature on the
                  signature page hereof


       if to Parent or Merger Sub:    EXELIXIS, INC.
                                      170 Harbor Way
                                      South San Francisco, CA 94083
                                      Attn: Chief Financial Officer
                                      Facsimile: (650) 837-8300

                                      ATHENS ACQUISITION CORP.
                                      c/o Exelixis, Inc.
                                      170 Harbor Way
                                      South San Francisco, CA 94083
                                      Attn: Chief Financial Officer
                                      Facsimile: (650) 837-8300

                                      IN EACH CASE WITH A COPY TO:

                                      Cooley Godward LLP




                                       6
<PAGE>


                                      Five Palo Alto Square
                                      3000 El Camino Real
                                      Palo Alto, CA 94306
                                      Attn:  Robert  L.  Jones  and  Suzanne
                                             Sawochka Hooper
                                      Facsimile: (650) 849-7400


      8.4   SEVERABILITY.  If any provision of this Voting Agreement or any part
of any  such  provision  is  held  under  any  circumstances  to be  invalid  or
unenforceable  in any  jurisdiction,  then (a) such  provision  or part  thereof
shall, with respect to such  circumstances and in such  jurisdiction,  be deemed
amended to conform to applicable  laws so as to be valid and  enforceable to the
fullest  possible  extent,  (b)  the  invalidity  or  unenforceability  of  such
provision  or part thereof  under such  circumstances  and in such  jurisdiction
shall not  affect the  validity  or  enforceability  of such  provision  or part
thereof under any other  circumstances or in any other  jurisdiction and (c) the
invalidity  or  unenforceability  of such  provision or part  thereof  shall not
affect the validity or  enforceability of the remainder of such provision or the
validity or enforceability of any other provision of this Voting Agreement. Each
provision of this Voting  Agreement is separable  from every other  provision of
this Voting Agreement,  and each part of each provision of this Voting Agreement
is separable from every other part of such provision.

      8.5   ENTIRE  AGREEMENT.  This Voting  Agreement,  the Proxy and any other
documents  delivered by the parties in connection herewith constitute the entire
agreement  between the parties  with  respect to the subject  matter  hereof and
thereof  and  supersede  all prior  agreements  and  understandings  between the
parties with respect thereto. No addition to or modification of any provision of
this Voting  Agreement shall be binding upon either party unless made in writing
and signed by both parties.

      8.6   ASSIGNMENT;  BINDING EFFECT. Except as provided herein, neither this
Voting  Agreement  nor any of the  interests  or  obligations  hereunder  may be
assigned or delegated by Stockholder  and any attempted or purported  assignment
or delegation of any of such interests or obligations shall be void.  Subject to
the preceding sentence,  this Voting Agreement shall be binding upon Stockholder
and his heirs,  estate,  executors,  personal  representatives,  successors  and
assigns,  and shall  inure to the  benefit  of  Parent  and its  successors  and
assigns.  Without  limiting  any of the  restrictions  set forth in Section 2 or
elsewhere in this Voting Agreement,  this Voting Agreement shall be binding upon
any  Person to whom any  Subject  Securities  are  transferred.  Nothing in this
Voting  Agreement is intended to confer on any Person (other than Parent and its
successors and assigns) any rights or remedies of any nature.

      8.7   SPECIFIC  PERFORMANCE.  The parties  agree that  irreparable  damage
would occur in the event that any of the provisions of this Voting  Agreement or
the  Proxy  was not  performed  in  accordance  with its  specific  terms or was
otherwise  breached.  Stockholder  agrees  that,  in the event of any  breach or
threatened breach by Stockholder of any covenant or obligation contained in this
Voting  Agreement or in the Proxy,  Parent shall be entitled (in addition to any
other remedy that may be available to it,  including  monetary  damages) to seek
and  obtain  (a) a decree  or order  of  specific  performance  to  enforce  the
observance and  performance of such covenant or




                                       7
<PAGE>


obligation and (b) an injunction  restraining such breach or  threatened breach.
Stockholder  further  agrees that  neither  Parent nor any other Person shall be
required to obtain, furnish or post any bond or similar instrument in connection
with or as a condition to obtaining any remedy  referred to in this Section 8.7,
and  Stockholder  irrevocably  waives  any  right  he may  have to  require  the
obtaining, furnishing or posting of any such bond or similar instrument.

      8.8   NON-EXCLUSIVITY. The rights and remedies of Parent under this Voting
Agreement are not exclusive of or limited by any other rights or remedies  which
it may have,  whether at law, in equity, by contract or otherwise,  all of which
shall be cumulative (and not  alternative).  Without  limiting the generality of
the  foregoing,  the rights and remedies of Parent under this Voting  Agreement,
and the obligations and liabilities of Stockholder  under this Voting Agreement,
are  in  addition  to  their  respective  rights,   remedies,   obligations  and
liabilities  under common law  requirements  and under all applicable  statutes,
rules and  regulations.  Nothing in this  Voting  Agreement  shall  limit any of
Stockholder's  obligations,  or the  rights or  remedies  of  Parent,  under any
Affiliate  Agreement  between  Parent and  Stockholder;  and nothing in any such
Affiliate Agreement shall limit any of Stockholder's obligations,  or any of the
rights or remedies of Parent, under this Voting Agreement.

      8.9   GOVERNING LAW; VENUE.

            (A) This  Voting  Agreement  and the  Proxy  shall be  construed  in
accordance  with,  and  governed  in all  respects  by, the laws of the State of
Delaware (without giving effect to principles of conflicts of laws).

            (B) Any legal  action or other  legal  proceeding  relating  to this
Voting Agreement or the Proxy or the enforcement of any provision of this Voting
Agreement  or the Proxy may be brought or  otherwise  commenced  in any state or
federal court located in the State of California. Stockholder:

            (i)   expressly  and   irrevocably   consents  and  submits  to  the
      jurisdiction  of each  state and  federal  court  located  in the State of
      California  (and each appellate court located in the State of California),
      in connection with any such legal proceeding;

            (ii) agrees that service of any process, summons, notice or document
      by U.S.  mail  addressed  to him at the  address  set forth in Section 8.3
      shall constitute  effective  service of such process,  summons,  notice or
      document for purposes of any such legal proceeding;

            (iii)agrees that each state  and federal  court located in the State
                  of California shall be deemed to be a convenient forum; and

            (iv) agrees  not to  assert  (by way of  motion,  as  a  defense  or
      otherwise), in any such legal proceeding commenced in any state or federal
      court located in the State of  California,  any claim that  Stockholder is
      not subject  personally to the jurisdiction of such court, that such legal
      proceeding has been brought in an  inconvenient  forum,  that the




                                       8
<PAGE>


      venue of such proceeding is improper or that this Voting  Agreement or the
      subject matter of this Voting Agreement may not be enforced in or  by such
      court.

Nothing  contained  in this  Section  8.9 shall be deemed to limit or  otherwise
affect the right of Parent to commence any legal proceeding or otherwise proceed
against Stockholder in any other forum or jurisdiction.

            (C)  STOCKHOLDER  IRREVOCABLY  WAIVES  THE RIGHT TO A JURY  TRIAL IN
CONNECTION WITH ANY LEGAL  PROCEEDING  RELATING TO THIS VOTING  AGREEMENT OR THE
PROXY OR THE ENFORCEMENT OF ANY PROVISION OF THIS VOTING AGREEMENT OR THE PROXY.

      8.10  COUNTERPARTS.  This Voting  Agreement may be executed by the parties
in separate counterparts,  each of which when so executed and delivered shall be
an original,  but all such  counterparts  shall together  constitute one and the
same instrument.

      8.11  CAPTIONS.  The captions  contained in this Voting  Agreement are for
convenience of reference  only,  shall not be deemed to be a part of this Voting
Agreement and shall not be referred to in connection  with the  construction  or
interpretation of this Voting Agreement.

      8.12  ATTORNEYS'  FEES.  If any  legal  action or other  legal  proceeding
relating to this Voting  Agreement or the  enforcement  of any provision of this
Voting Agreement is brought against  Stockholder,  the prevailing party shall be
entitled to recover  reasonable  attorneys'  fees, costs and  disbursements  (in
addition to any other relief to which the prevailing party may be entitled).

      8.13  WAIVER.  No  failure  on the part of Parent to  exercise  any power,
right, privilege or remedy under this Voting Agreement, and no delay on the part
of Parent in exercising any power, right,  privilege or remedy under this Voting
Agreement,  shall operate as a waiver of such power, right, privilege or remedy;
and no single or partial exercise of any such power, right,  privilege or remedy
shall  preclude  any other or further  exercise  thereof or of any other  power,
right,  privilege or remedy. Parent shall not be deemed to have waived any claim
available to Parent arising out of this Voting Agreement,  or any power,  right,
privilege or remedy of Parent under this Voting Agreement,  unless the waiver of
such  claim,  power,  right,  privilege  or remedy is  expressly  set forth in a
written instrument duly executed and delivered on behalf of Parent; and any such
waiver  shall  not be  applicable  or have any  effect  except  in the  specific
instance in which it is given.

      8.14  CONSTRUCTION.

            (A) For  purposes of this  Voting  Agreement,  whenever  the context
requires:  the singular  number shall  include the plural,  and vice versa;  the
masculine  gender shall  include the feminine and neuter  genders;  the feminine
gender shall  include the masculine  and neuter  genders;  and the neuter gender
shall include masculine and feminine genders.




                                       9
<PAGE>


            (B) The parties  agree that any rule of  construction  to the effect
that  ambiguities  are to be resolved  against the  drafting  party shall not be
applied in the construction or interpretation of this Voting Agreement.

            (C) As  used in this  Voting  Agreement,  the  words  "include"  and
"including,"  and  variations  thereof,  shall  not be  deemed  to be  terms  of
limitation,  but rather  shall be deemed to be  followed  by the words  "without
limitation."

            (D) Except as otherwise  indicated,  all  references  in this Voting
Agreement to "Sections" and "Exhibits" are intended to refer to Sections of this
Voting Agreement and Exhibits to this Voting Agreement.

































                                       10
<PAGE>



      IN WITNESS  WHEREOF,  Parent  and  Stockholder  have  caused  this  Voting
Agreement to be executed as of the date first written above.


                                          EXELIXIS, INC.

                                          By:
                                             ---------------------------------

                                          Name:  George A. Scangos

                                          Title:  President and Chief Executive
                                                  Officer





                                          STOCKHOLDER

                                             ---------------------------------
                                                      (SIGNATURE)

                                             ---------------------------------
                                                      (PRINT NAME)


                                          Address:
                                                  ----------------------------
                                                  ----------------------------
                                                  ----------------------------


                                          Facsimile:
                                                    --------------------------



SHARES HELD                OPTIONS AND                ADDITIONAL SECURITIES
OF RECORD                  OTHER RIGHTS               BENEFICIALLY OWNED
-----------                ------------               ---------------------














                                       11
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                                    EXHIBIT A

                            FORM OF IRREVOCABLE PROXY

      The undersigned stockholder of AGRITOPE, INC., a Delaware corporation (the
"Company"), hereby irrevocably (to the fullest extent permitted by law) appoints
and  constitutes  GEORGE  SCANGOS,  PH.D.,  GLEN Y. SATO and  EXELIXIS,  INC., a
Delaware corporation ("Parent"),  and each of them, the attorneys and proxies of
the undersigned with full power of substitution and resubstitution,  to the full
extent of the undersigned's rights with respect to (i) the outstanding shares of
capital stock of the Company owned of record by the  undersigned  as of the date
of this proxy,  which  shares are  specified on the final page of this proxy and
(ii) any and all  other  shares  of  capital  stock  of the  Company  which  the
undersigned may acquire on or after the date hereof.  (The shares of the capital
stock of the Company  referred to in clauses "(i)" and "(ii)" of the immediately
preceding  sentence  are  collectively  referred to as the  "Shares.")  Upon the
execution hereof, all prior proxies given by the undersigned with respect to any
of the Shares are hereby revoked,  and the undersigned agrees that no subsequent
proxies will be given with respect to any of the Shares.

      This proxy is  irrevocable,  is coupled with an interest and is granted in
connection  with the  Voting  Agreement,  dated as of the date  hereof,  between
Parent  and  the  undersigned  (the  "Voting  Agreement"),  and  is  granted  in
consideration  of Parent  entering  into the  Agreement  and Plan of Merger  and
Reorganization,  dated as of the date hereof,  among Parent,  Athens Acquisition
Corp. and the Company (the "Reorganization Agreement").

      The attorneys and proxies named above will be empowered,  and may exercise
this  proxy,  to vote the Shares at any time  until the  earlier to occur of the
valid termination of the  Reorganization  Agreement or the effective time of the
merger contemplated thereby (the "Merger") at any meeting of the stockholders of
the Company,  however called,  or in connection with any solicitation of written
consents from stockholders of the Company:

             (I)    in favor of the approval and adoption of the  Reorganization
Agreement and the approval of the Merger on the terms and  conditions  set forth
therein,  and  in  favor  of  each  of the  other  actions  contemplated  by the
Reorganization Agreement;

             (II)   against  any  action   or  agreement  that   to  the  actual
knowledge  of  Stockholder  would result in a material  breach of any  covenant,
representation  or warranty or any other  obligation or agreement of the Company
under the Reorganization Agreement; and

             (III)  against the following  actions  (other  than the  Merger and
the  transactions  contemplated  by  the  Reorganization   Agreement):  (A)  any
extraordinary  corporate transaction,  such as a merger,  consolidation or other
business combination involving the Company or any subsidiary of the Company; (B)
a sale,  lease or transfer of a material  amount of assets of the Company or any
subsidiary of the Company or a reorganization,  recapitalization, dissolution or
liquidation  of the Company or any  subsidiary  of the  Company;  or (C) (1) any
change in a majority of the board of directors of the Company; (2) any amendment
of the Company's Certificate of Incorporation;  (3) any other material change in
the present  capitalization  of the Company or any  amendment  of the  Company's
corporate  structure;  or (4) any other action which


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to the actual  knowledge of  Stockholder  is intended,  or could  reasonably  be
expected to impede,  interfere with,  delay,  postpone,  discourage or adversely
affect the contemplated  economic benefits to Parent of the Merger or any of the
other transactions  contemplated by the  Reorganization  Agreement or the Voting
Agreement.

      The undersigned may vote the Shares on all other matters.

      This proxy shall be binding upon the heirs,  estate,  executors,  personal
representatives,  successors  and  assigns  of the  undersigned  (including  any
transferee of any of the Shares).

      If any  provision of this proxy or any part of any such  provision is held
under any circumstances to be invalid or unenforceable in any jurisdiction, then
(a) such provision or part thereof shall, with respect to such circumstances and
in such  jurisdiction,  be deemed amended to conform to applicable laws so as to
be valid and enforceable to the fullest possible  extent,  (b) the invalidity or
unenforceability  of such provision or part thereof under such circumstances and
in such  jurisdiction  shall not affect the validity or  enforceability  of such
provision  or  part  thereof  under  any  other  circumstances  or in any  other
jurisdiction  and (c) the  invalidity or  unenforceability  of such provision or
part thereof shall not affect the validity or enforceability of the remainder of
such provision or the validity or  enforceability of any other provision of this
proxy.  Each provision of this proxy is separable from every other  provision of
this proxy,  and each part of each  provision  of this proxy is  separable  from
every other part of such provision.



























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      This proxy shall  terminate  upon the earlier of the valid  termination of
the Reorganization Agreement or the effective time of the Merger.

Dated:  September 7, 2000.
                                   STOCKHOLDER

                                   -----------------------------------------
                                                 (SIGNATURE)

                                   -----------------------------------------
                                                 (PRINT NAME)


                                   NUMBER OF SHARES OF  CAPITAL  STOCK OF
                                   THE COMPANY  OWNED OF RECORD AS OF THE
                                   DATE OF THIS PROXY:


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