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SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
SCHEDULE 13G
(RULE 13d-102)
INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
TO RULES 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO
FILED PURSUANT TO RULE 13d-2(b)
BIOMARIN PHARMACEUTICAL INC.
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(Name of Issuer)
COMMON STOCK, $0.001 PAR VALUE
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(Title of Class of Securities)
09061G 10 1
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(CUSIP Number)
July 23, 1999
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(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this
Schedule is filed:
/ / Rule 13d-1(b)
/ / Rule 13d-1(c)
/x/ Rule 13d-1(d)
*The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which
would alter the disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not
be deemed to be "filed" for the purpose of Section 18 of the Securities
Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that
section of the Act but shall be subject to all other provisions of the Act
(however, see the Notes).
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CUSIP NO. 09061G 10 1 13G PAGE 2 OF 6 PAGES
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(1) Names of Reporting Persons.
I.R.S. Identification Nos. of above persons (entities only).
Medical Portfolio Management, LLC
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(2) Check the Appropriate Box if a Member (a) / /
of a Group (See Instructions) (b) / /
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(3) SEC Use Only
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(4) Citizenship or Place of Organization
Delaware
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Number of Shares (5) Sole Voting Power
Beneficially 5,475,417
Owned by --------------------------------------------------
Each Reporting (6) Shared Voting Power
Person With: 0
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(7) Sole Dispositive Power
5,475,417
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(8) Shared Dispositive Power
0
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(9) Aggregate Amount Beneficially Owned by Each Reporting Person
5,475,417
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(10) Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See
Instructions) / /
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(11) Percent of Class Represented by Amount in Row (9)
15.7%
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(12) Type of Reporting Person (See Instructions)
OO
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CUSIP NO. 09061G 10 1 13G PAGE 3 OF 6 PAGES
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ITEM 1(a). NAME OF ISSUER:
BioMarin Pharmaceutical Inc.
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ITEM 1(b). ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
371 Bel Marin Keys Boulevard, Suite 210, Novato, CA 94949
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ITEM 2(a). NAME OF PERSON FILING:
Medical Portfolio Management, LLC
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ITEM 2(b). ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE:
One Cambridge Center, Cambridge, MA 02142
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ITEM 2(c). CITIZENSHIP:
A Delaware corporation
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ITEM 2(d) TITLE OF CLASS OF SECURITIES:
Common Stock, par value $0.001 per share
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ITEM 2(e) CUSIP NUMBER:
09061G 10 1
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ITEM 3. IF THIS STATEMENT IS FILED PURSUANT TO RULES 13d-1(b), OR
13d-2(b), CHECK WHETHER THE PERSON FILING IS A:
Not applicable.
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CUSIP NO. 09061G 10 1 13G PAGE 4 OF 6 PAGES
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ITEM 4. OWNERSHIP.
(a) Amount beneficially owned:
5,475,417(1)
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(b) Percent of class:
15.7%
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(c) Number of shares as to which such person has:
(i) Sole power to vote or to direct the vote 5,475,417
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(ii) Shared power to vote or to direct the vote 0
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(iii) Sole power to dispose or to direct the disposition of 5,475,417
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(iv) Shared power to dispose or to direct the disposition of 0
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ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.
Not applicable.
ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER
PERSON.
Various persons have the right to receive or the power to
direct the receipt of dividends from, or the proceeds from the
sale of, the shares to which this statement relates. No one
person's interest in such shares is more than five percent of
the total outstanding stock of the Issuer.
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(1) These shares include shares held by funds and accounts managed
or advised by MPM Asset Management LLC, an indirect subsidiary
of the Reporting Person.
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CUSIP NO. 09061G 10 1 13G PAGE 5 OF 6 PAGES
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ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH
ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING
COMPANY.
Not applicable.
ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.
Not applicable.
ITEM 9. NOTICE OF DISSOLUTION OF GROUP.
Not applicable.
ITEM 10. CERTIFICATION.
Not applicable.
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SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.
Dated: February 25, 2000 By: MEDICAL PORTFOLIO MANAGEMENT, LLC
By: /s/ Luke B. Evnin
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Name: Luke B. Evnin
Title: Treasurer
