ATHERSYS INC /OH
S-1, EX-10.12, 2000-10-12
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<PAGE>   1
                                                                   Exhibit 10.12


                                                                  Execution Copy





                                FUNDING AGREEMENT

                                      AMONG

                       ELAN PHARMA INTERNATIONAL LIMITED,

                              ELAN CORPORATION, PLC

                                       AND


                        ELAN INTERNATIONAL SERVICES, LTD.


                                       AND


                                 ATHERSYS, INC.










<PAGE>   2



                                    CONTENTS
                                    --------


CLAUSE 1    SUBSEQUENT FUNDING

CLAUSE 2    TERMINATION

CLAUSE 3    MISCELLANEOUS



                                       i
<PAGE>   3



FUNDING AGREEMENT made this 21st day of October, 1999

AMONG:

(1)      ELAN PHARMA INTERNATIONAL LIMITED, a private limited company
         incorporated under the laws of Ireland having its registered office at
         WIL House, Shannon Business Park, Shannon, County Clare, Ireland, and,
         ELAN CORPORATION, PLC, a public limited company under the laws of
         Ireland, and each having its registered office at Lincoln House,
         Lincoln Place, Dublin 2, Ireland ("collectively, ELAN");

(2)      ELAN INTERNATIONAL SERVICES, LTD., an exempted limited liability
         company incorporated under the laws of Bermuda, and having its
         registered office at Clarendon House, 2 Church St., Hamilton, Bermuda
         ("EIS"); and

(3)      ATHERSYS, INC., a corporation incorporated under the laws of Delaware
         and having its principal place of business at 11000 Cedar Avenue,
         Cleveland, Ohio 44106, United States of America ("ATHERSYS").


RECITALS:

A.       EIS and Athersys have formed a Bermuda private limited company to be
         known as Athersys Newco Ltd., an exempt Bermuda company, incorporated
         on the 18th day of October, 1999 ("NEWCO").

B.       Elan is beneficially entitled to the use of certain patents which have
         been granted or are pending in relation to Medipad Technology.

C.       Athersys is beneficially entitled to the use of certain patents that
         have been granted or are pending in relation to its RAGE Technology.

D.       As of the date hereof, Elan has entered into a license agreement with
         Newco, and Athersys has entered into a license agreement with Newco, in
         connection with the license to Newco of the Elan Intellectual Property
         and the Athersys Intellectual Property, respectively.

E.       Elan and Athersys have agreed to co-operate in the research,
         development and commercialization of the Products based on their
         respective technologies.

F.       As of the date hereof, Elan, EIS, Athersys and Newco have entered into
         a Subscription, Joint Development and Operating Agreement dated as of
         the date hereof (the "JDOA") for the purpose of recording the terms and
         conditions of the research, development and commercialization of the
         Products and governing certain aspects of the affairs of and their
         dealings with Newco. The parties have agreed that capitalized terms
         when used in these

<PAGE>   4

         Recitals and in this Agreement shall bear the same meanings as ascribed
         to such terms in the JDOA.

                                    CLAUSE 1

                               SUBSEQUENT FUNDING

1.1      It is estimated that Newco will require an additional U.S. $5,000,000
         to commence development of the Products based upon the Athersys
         Intellectual Property, the Elan Intellectual Property and/or the Newco
         Technology (the "SUBSEQUENT FUNDING"). Within 36 months of the Closing
         Date, EIS and Athersys may provide to Newco, each by way of either (i)
         a capital contribution without the issuance of additional shares or
         (ii) a loan, as EIS and Athersys may agree, up to an aggregate maximum
         amount of U.S. $5,000,000, such funding to be provided on a pro rata
         basis in accordance with their respective ownership interest in Newco,
         taking into account all classes of share ownership (i.e., initially,
         80.1% by Athersys and 19.9% by EIS).

1.2      The Subsequent Funding shall be provided by EIS and Athersys at such
         times that shall be provided for the development of the Products as
         provided in the Business Plan or as otherwise approved by the Newco
         Directors, including the Newco Director designated by EIS (or after the
         Exchange Right, by all of the Newco Directors designated by EIS). The
         Subsequent Funding shall be funded on the following terms and subject
         to the following conditions:

         1.2.1    The minimum amount of each disbursement of the Subsequent
                  Funding shall be U.S.$250,000 (except in the event that an
                  amount less than U.S.$250,000 remains available for funding,
                  in which case such lesser amount may be funded);

         1.2.2    There shall be no Event of Default (as defined in the
                  Convertible Note and the Senior Note) under the Convertible
                  Note or the Senior Note on the date of the Subsequent Funding
                  (except to the extent that any Event of Default has been
                  waived by EIS); and

         1.2.3    Such funding shall be provided in accordance with the Business
                  Plan and the Research and Development Plan or as otherwise
                  approved by the Newco Board of Directors (including at least
                  one Newco Director designated by EIS and one Newco Director
                  designated by Athersys); and

         1.2.4    Such funding shall be subject to the receipt by Elan or EIS of
                  any required approvals under the Mergers and Takeovers
                  (Control) Acts 1978-1996 (the "IRISH MERGERS ACT").

1.3      In the event that Elan or EIS is unable to obtain any required approval
         under the Irish Mergers Act within 45 days after a determination of the
         necessity of such funding by the Newco Directors, the parties hereto
         shall work together in good faith, each in its sole discretion, to
         agree on an alternative funding mechanism.

                                       3
<PAGE>   5

1.4      Each request for Subsequent Funding shall be delivered from Newco to
         each of Athersys and EIS, which notice shall set forth:

         (i)      the amount of the Subsequent Funding requested and the portion
                  of such amount to be contributed or lent, as the case may be,
                  by each of Athersys and EIS;

         (ii)     the date requested to fund such amount (which date (A) shall
                  not be fewer than 15 days following the date of the request
                  for such subsequent Funding and (B) with respect to Athersys,
                  shall not be a date earlier than Athersys receives a
                  disbursement under the Note to permit funding of its share of
                  the Subsequent Funding, if applicable); and

         (iii)    a reasonably detailed narrative and summary of the uses and
                  application thereof.

1.5      Subject to the following paragraph, the first available net income
         received by Newco, in respect of amounts, if any of third party
         licensing fees, royalties, milestone payments or other amounts
         thereafter in respect of the marketing or licensing of products and/or
         intellectual property, shall be repaid or distributed to Athersys and
         EIS in proportion to their respective equity interests in Newco until
         such time as the full amounts of the Subsequent Funding have been
         repaid or distributed to Athersys and EIS. Such amounts shall be repaid
         or distributed at such time or times as approved by the Newco Board of
         Directors (including the approval of at least one Newco Director
         designated by EIS and one Newco Director designated by Athersys).

         In the event that EIS exercises its right to convert the Convertible
         Exchangeable Preferred Stock rather than exercising the Exchange Right,
         then, in such event, the net income in respect of amounts, if any, of
         third party licensing fees, royalties, milestone payments or other
         amounts received by Newco thereafter in respect of the marketing or
         licensing of products and/or intellectual property, shall be applied to
         (w) repayment of the Subsequent Funding or distribution of the full
         amounts thereunder to Athersys and EIS, as the case may be, (x) as to
         the next U.S. $15,000,000 of such net income, 100% to Athersys, and (y)
         as to any amounts in excess of (w) and (x), above, to the parties in
         proportion to their respective equity interests in Newco. Such amounts
         shall be distributed at such time or times that the Newco Board of
         Directors (with the approval of at least one Newco Director designated
         by EIS and one Newco Director designated by Athersys) shall deem to be
         appropriate.


                                    CLAUSE 2

                                   TERMINATION

2.1      This Agreement shall govern the funding methodology of EIS and Athersys
         with respect to Newco until (i) terminated by written agreement of all
         parties hereto or (ii) all of the Subsequent Funding amounts due under
         this Agreement have been repaid or distributed, as

                                       4
<PAGE>   6

         the case may be.


                                    CLAUSE 3

                                  MISCELLANEOUS

3.1      GOOD FAITH:
         -----------

         Each of the parties hereto undertakes with the others to do all things
         reasonably within its power that are necessary or desirable to give
         effect to the spirit and intent of this Agreement.

3.2      FURTHER ASSURANCE:
         ------------------

         At the request of any of the parties, the other party or parties shall
         (and shall use reasonable efforts to procure that any other necessary
         parties shall) execute and perform all such documents, acts and things
         as may reasonably be required subsequent to the signing of this
         Agreement for assuring to or vesting in the requesting party the full
         benefit of the terms hereof.

3.3      RELIANCE ON REPRESENTATIONS AND WARRANTIES:
         -------------------------------------------

         Each of the parties hereto hereby acknowledges that in entering into
         this Agreement it has not relied on any representation or warranty
         except as expressly set forth herein or in any document referred to
         herein.

3.4      FORCE MAJEURE:
         --------------

         Neither party to this Agreement shall be liable for delay in the
         performance of any of its obligations hereunder if such delay is caused
         by or results from causes beyond its reasonable control, including
         without limitation, acts of God, fires, strikes, acts of war (whether
         war be declared or not), insurrections, riots, civil commotions,
         strikes, lockouts or other labor disturbances or intervention of any
         relevant government authority, but any such delay or failure shall be
         remedied by such party as soon as practicable.

3.5      RELATIONSHIP OF THE PARTIES:
         ----------------------------

         Nothing contained in this Agreement is intended or is to be construed
         to constitute Elan or EIS, on one hand, and Athersys, on the other
         hand, as partners, or Elan or EIS as an employee or agent of Athersys,
         or Athersys as an employee or agent of Elan or EIS.

         No party hereto shall have any express or implied right or authority to
         assume or create any obligations on behalf of or in the name of another
         party or to bind another party to any contract, agreement or
         undertaking with any third party.

                                       5
<PAGE>   7

3.6      COUNTERPARTS:
         -------------

         This Agreement may be executed in any number of counterparts, and each
         such counterpart hereof shall be deemed to be an original instrument,
         but all such counterparts together shall constitute one agreement. This
         Agreement may be signed and delivered to the other party by facsimile
         transmission; such transmission shall be deemed a valid signature.


3.7      NOTICES:
         --------

         All notices, demands and requests of any kind to be delivered to any
         party in connection with this Agreement shall be in writing and shall
         be deemed to have been duly given if personally delivered or if sent by
         nationally-recognized overnight courier or by registered or certified
         mail, return receipt requested and postage prepaid, or by facsimile
         transmission, addressed as follows:

         Elan at:

         Lincoln House, Lincoln Place, Dublin 2
         Ireland
         Attention:  Vice President & General Counsel
         Elan Pharmaceutical Technologies,
         a division of Elan Corporation, plc
         Telephone:        353-1-709-4000
         Fax:              353-1-709-4124

         with a copy to:

         Brock Silverstein LLC
         800 Third Avenue, 21st Floor
         New York, NY 10022
         Attention:  David Robbins, Esq.
         Telephone         212-371-2000
         Fax:              212-371-5500

         EIS at:

         Elan International Services, Ltd.
         102 St. James Court
         Flatts, Smiths FL04
         Bermuda
         Attention:  President
         Telephone:        441-292-9169
         Fax:              441-292-2224

                                       6
<PAGE>   8

         with a copy to:

         Brock Silverstein LLC
         800 Third Avenue, 21st Floor
         New York, NY 10022
         Attention:  David Robbins, Esq.
         Telephone         212-371-2000
         Fax:              212-371-5500

         Athersys at:

         11000 Cedar Avenue
         Cleveland, Ohio  44106
         Attention:  President and Chief Executive Officer
         Telephone: (216) 231-9911
         Facsimile:  (216) 231-0905

         with a copy to:

         Jones, Day, Reavis & Pogue
         901 Lakeside Avenue
         Cleveland, Ohio  44114
         Attention:  Christopher M. Kelly, Esq.
         Telephone:        216-586-3939
         Fax:              216-579-0212

         Each party, by written notice given to the other in accordance with
         this Section 3.7 may change the address to which notices, other
         communication or documents are to be sent to such party. All notices,
         other communications or documents shall be deemed to have been duly
         given when received. Any such notice or communication shall be deemed
         to have been effectively given, (a) in the case of personal delivery,
         on the date of such delivery, (b) in the case of nationally-recognized
         overnight courier, on the second business day after the date when sent,
         (c) in the case of mailing, on the fifth business day following that
         day on which the piece of mail containing such communication is posted,
         and (d) in the case of facsimile transmission, on the date of
         transmission.

3.8      GOVERNING LAW:
         --------------

         This Agreement shall be governed by and construed in accordance with
         the internal laws of the State of New York, without giving effect to
         principles of conflicts of laws. Any dispute hereunder shall be
         adjudicated in a forum set forth in the JDOA.

                                       7
<PAGE>   9

3.9      SEVERABILITY:
         -------------

         In case any provision of this Agreement is deemed to be invalid,
         illegal or unenforceable, the validity, legality and enforceability of
         the remaining provisions shall not be in any way affected or impaired
         thereby.

3.10     AMENDMENTS:
         -----------

         This Agreement may not be modified or amended, or any of the provisions
         hereof waived, except by written agreement of the Company and EIS.

3.11     WAIVER:
         -------

         No waiver of any right under this Agreement shall be deemed effective
         unless contained in a written document signed by the party charged with
         such waiver, and no waiver of any breach or failure to perform shall be
         deemed to be a waiver of any future breach or failure to perform or of
         any other right arising under this Agreement.

3.12     ASSIGNMENT:
         -----------

         None of the parties shall be permitted to assign its rights or
         obligations hereunder without the prior written consent of the other
         parties except as follows:

         3.12.1    Elan, EIS and/or Athersys shall have the right to assign
                   their rights and obligations hereunder to their respective
                   Affiliates, PROVIDED, HOWEVER, that such assignment does not
                   result in adverse tax consequences for any other parties
                   PROVIDED, HOWEVER, that the assigning party shall remain
                   liable for its obligations hereunder after such assignment

         3.12.2    Elan and EIS shall have the right to assign their rights
                   hereunder to a special purpose financing or similar vehicle
                   established by Elan or EIS; PROVIDED, HOWEVER, that the
                   assigning party shall remain liable for its obligations
                   hereunder after such assignment.

         3.12.3    Elan, EIS and/or Athersys shall have the right to assign or
                   otherwise transfer their rights and obligations hereunder in
                   connection with a sale of all or substantially all of the
                   business of such party, whether by merger, sale of stock,
                   sale of assets or otherwise.

3.13     ENTIRE AGREEMENT:
         -----------------

         This Agreement, the Confidentiality Agreement and the other Transaction
         Documents contain the entire understanding of the parties with respect
         to the subject matter hereof and supersede and terminate all prior
         agreement and understanding among the parties with respect thereto.


                                       8
<PAGE>   10

3.14     SUCCESSORS:
         -----------

         This Agreement and all of the provisions hereof shall be binding upon
         and inure to the benefit of the parties hereto and their respective
         successors and permitted assigns

3.15     EXPENSES:
         ---------

         Each of the parties shall be responsible for its own costs and expenses
         incurred in connection with the transactions contemplated hereby.

3.16     HEADINGS; REFERENCES:
         ---------------------

         The section and paragraph headings contained in this Agreement are for
         reference purposes only and shall not affect in any way the meaning or
         interpretation of the Agreement. Unless the context requires otherwise,
         references to "Sections" in this Agreement are references to Section of
         this Agreement.


                         [SIGNATURES ON FOLLOWING PAGE]


                                       9
<PAGE>   11

                  IN WITNESS WHEREOF, the parties hereto have caused their
respective duly authorized representatives to have executed this Funding
Agreement on the day first set forth above.

                                               SIGNED

                                               BY: /s/ Kevin Insley
                                                  -----------------------

                                               for and on behalf of
                                               ELAN PHARMA INTERNATIONAL LIMITED

in the presence of: /s/ Kim Burgess
                    ---------------


                                               SIGNED

                                               BY: /s/ Kevin Insley
                                                  -----------------------

                                               for and on behalf of
                                               ELAN CORPORATION, plc

in the presence of: /s/ Kim Burgess
                    ---------------

                                               SIGNED

                                               BY: /s/ Kevin Insley
                                                  -----------------------

                                               for and on behalf of
                                               ELAN INTERNATIONAL SERVICES, LTD.

in the presence of: /s/ Kim Burgess
                    ---------------


                                               SIGNED

                                               BY: /s/ Gil Van Bokkelen
                                                  -----------------------

                                               for and on behalf of
                                               ATHERSYS, INC.

in the presence of: /s/ James J. Kovach
                   --------------------


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