UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Form 13F
Form 13F COVER PAGE
Report for the Calendar Year or Quarter Ended: September 30, 2000
Check here if Amendment: |_|; Amendment Number: ____
This Amendment (Check only one): |_| is a restatement.
|_| adds new holdings
entries.
Institutional Investment Manager Filing this Report:
Name: OrbiMed Advisers LLC
Address: 767 Third Avenue, 6th Floor
New York, NY 10010
Form 13F File Number: 28-6774
The institutional investment manager filing this report and the person by whom
it is signed hereby represent that the person signing the report is authorized
to submit it, that all information contained herein is true, correct and
complete, and that it is understood that all required items, statements,
schedules, lists, and tables, are considered integral parts of this form.
Person Signing this Report on Behalf of Reporting Manager:
Name: Samuel D. Isaly
Title: President
Phone: (212) 739-6400
Signature, Place, and Date of Signing:
Samuel D. Isaly New York, NY November 15, 2000
[Signature] [City, State] [Date]
Report Type (Check one only):
[ ] 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager
are reported in this report.)
[ ] 13F NOTICE. (Check here if no holdings reported are in this report, and all
holdings are reported by other reporting manager(s).)
[X] 13F COMBINATION REPORT. (Check here if a portion of the holdings for this
reporting manager are reported in this report and a portion are reported by
other reporting manager(s).)
--------------------------------------------------------------------------------
Page 1
<PAGE>
Form 13F SUMMARY PAGE
Report Summary:
Number of Other Included Managers: 0
Form 13F Information Table Entry Total: 3
Form 13F Information Table Value Total: $32,207,740
List of Other Included Managers: NONE
Provide a numbered list of the name(s) and Form 13F file nember(s) of all
institutional investment managers with respect to which this report is filed,
other than the manager filing this report.
[If there are no entries in this list, state "NONE" and omit the column headings
and list entries.]
--------------------------------------------------------------------------------
Page 2
<PAGE>
FORM 13F INFORMATION TABLE
<TABLE>
<CAPTION>
---------------------------------------------------------------------------------------------------------------------------------
Column 1 Column 2 Column 3 Column 4 Column 5 Column 6
---------------------------------------------------------------------------------------------------------------------------------
Investment Discretion
Shared Shared
Name of Issuer Title of Class CUSIP Number Market Value SHRS Sole Defined Other
---------------------------------------------------------------------------------------------------------------------------------
<S> <C> <C> <C> <C> <C>
Celgene Corp. COM 151020104 3,915,754 65,811 X
Discovery Laboratories Inc. COM 2546681C6 25,901,361 3,512,049 X
Genta Inc. COM 37245M207 2,390,625 250,000 X
---------------------------------------------------------------------------------------------------------------------------------
</TABLE>
---------------------------------------------------------------------------
Column 1 Column 7 Column 8
---------------------------------------------------------------------------
Voting Authority (Shares)
Other
Name of Issuer Managers Sole Shared None
---------------------------------------------------------------------------
Celgene Corp. 65,811
Discovery Laboratories Inc. 3,512,049
Genta Inc. 250,000
---------------------------------------------------------------------------
