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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Form 13F
Form 13F COVER PAGE
Report for the Calendar Year Ended: December 31, 1999
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Check here if Amendment [ ]; Amendment Number:
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This Amendment [Check only one.]: [ ] is a restatement
[ ] adds new holdings entries
Institutional Investment Manager Filing this Report:
Name: BVF Inc.
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Address: 227 West Monroe Street, Suite 4800
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Chicago, Illinois 60606
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Form 13F File Number: 28-6800
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The institutional investment manager filing this report and the person by whom
it is signed hereby represent that the person signing the report is authorized
to submit it, that all information contained herein is true, correct and
complete, and that it is understood that all required items, statements,
schedules, lists, and tables, are considered integral parts of this form. Person
Signing this Report on Behalf of Reporting Manager:
Name: Mark N. Lampert
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Title: President
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Phone: (312) 263-7777
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Signature, Place and Date of Signing:
/s/ Mark N. Lampert San Francisco, California 2/11/00
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[Signature] [City, State] [Date]
Report Type (Check only one):
[ X ] 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager
are reported in this report.)
[ ] 13F NOTICE. (Check here if no holdings reported are in this report,
and all holdings are reported by other reporting manager(s)).
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[ ] 13F COMBINATION REPORT. (Check here if a portion of the holdings for
this reporting manager are reported in this report and a portion are
reported by other reporting manager(s).)
Report Summary:
Number of Other Included Managers: 1
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Form 13F Information Table Entry Total: 34
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Form 13F Information Table Value Total: $180,087
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(thousands)
List of Other Included Managers:
Provide a numbered list of the name(s) and Form 13F file number(s) of all
institutional investment managers with respect to which this report is filed,
other than the manager filing this report.
[If there are no entries in this list, state "NONE" and omit the column headings
and list entries.]
No. Form 13F File Number Name
1. 28-6770 BVF PARTNERS L.P.
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Page 3 of 4
FORM 13F
Name of Reporting Manager: BVF Inc.
<TABLE>
<CAPTION>
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Column 1: Column 2: Column 3: Column 4: Column 5:
Name of Issuer Title of CUSIP Value
Class (x$1000) ------------------------------
Shrs Sh/ Put/
Prn Prn Call
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<S> <C> <C> <C> <C> <C> <C>
Advanced Magnetics Inc Com 00753P103 4,027 976,235 Sh
Aquila Biopharm Inc Com 03839F107 748 315,126 Sh
Ariad Pharmaceuticals Warrant 04033A100 75 133,500 Sh
Ariad Pharmaceuticals Com 04033A100 5,766 2,049,600 Sh
Arqule Inc Com 04269E107 10,731 1,046,900 Sh
Autoimmune Inc Com 052776101 1,950 2,398,300 Sh
Biochem Pharmaceuticals Inc. Com 09058T108 235 10,809 Sh
Cadus Pharmaceutical Corp Com 127639102 282 900,000 Sh
Cell Genesys Inc. Com 150921104 1,717 134,000 Sh
Cortech Inc Com 22051J100 1,080 183,774 Sh
Corvas Intl Inc Com 221005101 9,261 2,086,643 Sh
Creative Biomolecules Inc Com 225270107 288 58,300 Sh
Epimmune Inc. Com 29425Y101 113 43,500 Sh
Genome Therapeutics Corp Com 372430108 11,947 740,885 Sh
Immunogen Inc. Com 45253H101 8,717 1,584,819 Sh
Magainin Pharmaceuticals Inc Com 559036108 220 121,100 Sh
Microcide Pharmaceuticals Inc Com 595018102 17,498 1,971,600 Sh
Neurocrine Bioscience Inc Com 64125C109 2,012 81,300 Sh
Neurogen Corp Com 64124E106 19,902 1,206,206 Sh
NPS Pharmaceuticals Inc Com 62936P103 3,137 256,114 Sh
OSI Pharmaceuticals Inc Com 671040103 19,756 2,488,790 Sh
Protein Polymer Technologies Com 743697104 123 652,000 Sh
QLT Phototherapeutics Inc Com 746927102 464 6,230 Sh
SIBIA Neurosciences Inc Com 825732100 12,164 1,431,000 Sh
Synaptic Pharmaceutical Corp Com 87156R109 10,144 1,502,817 Sh
Titan Pharmaceuticals Inc Del Com 888314101 831 43,750 Sh
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COLUMN TOTAL 143,188
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<CAPTION>
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(SEC USE ONLY)
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Column 1: Column 6: Column 7: Column 8:
Name of Issuer Investment Other Voting Authority
Discretion Managers -----------------------------------------
Sole Shared None
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<S> <C> <C> <C> <C> <C>
Advanced Magnetics Inc Defined 1 976,235
Aquila Biopharm Inc Defined 1 315,126
Ariad Pharmaceuticals Defined 1 133,500
Ariad Pharmaceuticals Defined 1 2,049,600
Arqule Inc Defined 1 1,046,900
Autoimmune Inc Defined 1 2,398,300
Biochem Pharmaceuticals Inc. Defined 1 10,809
Cadus Pharmaceutical Corp Defined 1 900,000
Cell Genesys Inc. Defined 1 134,000
Cortech Inc Defined 1 183,774
Corvas Intl Inc Defined 1 2,086,643
Creative Biomolecules Inc Defined 1 58,300
Epimmune Inc. Defined 1 43,500
Genome Therapeutics Corp Defined 1 740,885
Immunogen Inc. Defined 1 1,584,819
Magainin Pharmaceuticals Inc Defined 1 121,100
Microcide Pharmaceuticals Inc Defined 1 1,971,600
Neurocrine Bioscience Inc Defined 1 81,300
Neurogen Corp Defined 1 1,206,206
NPS Pharmaceuticals Inc Defined 1 256,114
<CAPTION>
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Column 1: Column 6: Column 7: Column 8:
Name of Issuer Investment Other Voting Authority
Discretion Managers -----------------------------------------
Sole Shared None
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<S> <C> <C> <C> <C> <C>
OSI Pharmaceuticals Inc Defined 1 2,488,790
Protein Polymer Technologies Defined 1 652,000
QLT Phototherapeutics Inc Defined 1 6,230
SIBIA Neurosciences Inc Defined 1 1,431,000
Synaptic Pharmaceutical Corp Defined 1 1,502,817
Titan Pharmaceuticals Inc Del Defined 1 43,750
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COLUMN TOTAL
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Page 4 of 4
FORM 13F
Name of Reporting Manager: BVF Inc.
<CAPTION>
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Column 1: Column 2: Column 3: Column 4: Column 5:
Name of Issuer Title of CUSIP Value
Class (x$1000) ------------------------------
Shrs Sh/ Put/
Prn Prn Call
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<S> <C> <C> <C> <C> <C> <C>
Amgen Inc Com 031162100 1,682 28,000 Sh Put
Biogen Inc. Com 090597105 4,648 55,000 Sh Put
Chiron Corp Com 170040109 4,238 100,000 Sh Put
Genzyme Corp Com 372917609 900 20,000 Sh Put
Glaxo Wellcome PLC Com 37733W105 6,035 108,000 Sh Put
Sponsored ADR
Put
Johnson & Johnson Com 478160104 10,817 116,000 Sh Put
Merck & Co Inc Com 589331107 6,719 100,000 Sh Put
Smithkline Beecham PLC Com 832378301 1,860 29,000 Sh
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COLUMN TOTAL 36,899
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CUMULATIVE TOTAL 180,087
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<CAPTION>
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(SEC USE ONLY)
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Column 1: Column 6: Column 7: Column 8:
Name of Issuer Investment Other Voting Authority
Discretion Managers -----------------------------------------
Sole Shared None
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<S> <C> <C> <C> <C> <C>
Amgen Inc Defined 1 28,000
Biogen Inc. Defined 1 55,000
Chiron Corp Defined 1 100,000
Genzyme Corp Defined 1 20,000
Glaxo Wellcome PLC Defined 1 108,000
Sponsored ADR
Johnson & Johnson Defined 1 116,000
Merck & Co Inc Defined 1 100,000
Smithkline Beecham PLC Defined 1 29,000
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COLUMN TOTAL
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CUMULATIVE TOTAL
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</TABLE>