SIMS MOSS KLINE & DAVIS LLP
                       400 Northpark Town Center Suite 310
                            1000 Abernathy Road, N.E.
                             Atlanta, Georgia 30328
                            Telephone: (770) 481-7200
                            Facsimile: (770) 481-7210



October 7, 1998

U.S. Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C.  20549

         Re:      Bioshield Technologies, Inc.
         File No.  333-57767
         424 (c)

Dear Sir or Madam:

We transmit  herewith the post  effective  amendment to the final  prospectus of
Bioshield Technologies, Inc as required by Section 424(c) of the Securities Act.

                                                     Very truly yours,

                                             SIMS MOSS KLINE & DAVIS LLP



                                                     By:   /s/ Raymond L. Moss
                                                              Raymond L. Moss
         

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                SUPPLEMENT, DATED OCTOBER 6, 1998, TO PROSPECTUS,
            DATED SEPTEMBER 29, 1998, OF BIOSHIELD TECHNOLOGIES, INC.


The following  amends and restates the final sentence of the second paragraph of
page 1 of the Prospectus:

"The Units are traded on The NASDAQ SmallCap Market  ("NASDAQ") under the symbol
"BSTIU." The Company  intends to make  application  to list the Common Stock and
Warrants  for  trading  on  NASDAQ   under  the  symbols   "BSTI"  and  "BSTIW,"
respectively, prior to their becoming separably tradable.



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