POZEN INC /NC
8-A12G, 2000-10-06
PHARMACEUTICAL PREPARATIONS
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 8-A


               For Registration of Certain Classes of Securities
                   Pursuant to Section 12(b) or 12(g) of the
                        Securities Exchange Act of 1934



                                  POZEN INC.
-------------------------------------------------------------------------------
                (Exact name of registrant specified in Charter)


            DELAWARE                                    62-1657552
-------------------------------------------------------------------------------
         (State or other                               (IRS Employee
         jurisdiction of                             Identification No.)
         incorporation)

       6330 Quadrangle Drive
            Suite 240                                      27514
     Chapel Hill, North Carolina
-------------------------------------------------------------------------------
 (Address of principal executive offices)                 Zip Code

If this Form relates to the registration of a class of securities pursuant to
Section 12(b) of the Exchange Act and is effective pursuant to General
Instruction A. (c), please check the following box. [ ]

If this Form relates to the registration of a class of securities pursuant to
Section 12(g) of the Exchange Act and is effective pursuant to General
Instruction A. (d), please check the following box. [X]

Securities Act registration statement file number to which this form relates:
                                                                333-35930
                                                               ------------

       Securities to be registered pursuant to Section 12(b) of the Act:

           Title of Each Class                    Name of Each Exchange on Which
           to be so Registered                    Each Class is to be Registered
           -------------------                    ------------------------------

              Not Applicable                               Not Applicable
-------------------------------------------------------------------------------


       Securities to be registered pursuant to Section 12(g) of the Act:

                         Common Stock, $0.001 par value
                         ------------------------------
                                (Title of class)
<PAGE>

Item 1.   Description of Registrant's Securities to be Registered
          -------------------------------------------------------

     The Registrant is registering shares of Common Stock, $0.001 par value per
share, pursuant to a Registration Statement on Form S-1 (File No. 333-35930)
that was filed with the Securities and Exchange Commission on April 28, 2000
(the "Registration Statement").  Reference is made to the sections entitled
"Prospectus Summary" and "Description of Capital Stock" in the prospectus
forming a part of the Registration Statement, and all amendments to the
Registration Statement subsequently filed with the Commission, including any
prospectus relating thereto filed subsequently pursuant to Rule 424 of the
Securities Act of 1933, as amended.  Such Registration Statement and all
amendments to the Registration Statement are hereby deemed to be incorporated by
reference into this Registration Statement in accordance with the Instruction to
Item 1 of this Form.

Item 2.   Exhibits.
          --------

     3.1  Amended and Restated Articles of Incorporation of the Registrant
          (Incorporated by reference to Exhibit 3.1 to the Registration
          Statement on Form S-1 (File No. 333-35930) of the Registrant, as
          amended).

     3.2  Amended and Restated Bylaws of the Registrant (Incorporated by
          reference to Exhibit 3.2 to the Registration Statement on Form S-1
          (File No. 333-35930) of the Registrant, as amended).

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<PAGE>

                                 SIGNATURES
                                 ----------


     Pursuant to the requirements of Section 12 of the Securities Exchange Act
of 1934, as amended, the Registrant has duly caused this registration statement
to be signed on its behalf by the undersigned, thereunto duly authorized.


                                      POZEN INC.



                                      By:  /s/ John R. Plachetka
                                           ____________________________
                                      Name:  John R. Plachetka
Dated: October 6, 2000                Title: Chief Executive Officer

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