<PAGE> PAGE 1
000 B000000 10/31/99
000 C000000 0001062417
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 6.1
000 J000000 A
001 A000000 ALLIANCE SELECT INVESTOR SERIES, INC.
001 B000000 811-09176
001 C000000 2013194105
002 A000000 500 PLAZA DRIVE
002 B000000 SECAUCUS
002 C000000 NJ
002 D010000 07094
003 000000 Y
004 000000 N
005 000000 N
006 000000 N
007 A000000 Y
007 B000000 1
007 C010100 1
007 C020100 PREMIER PORTFOLIO
007 C030100 N
007 C010200 2
007 C010300 3
007 C010400 4
007 C010500 5
007 C010600 6
007 C010700 7
007 C010800 8
007 C010900 9
007 C011000 10
008 A00AA01 ALLIANCE CAPITAL MANAGEMENT, L.P.
008 B00AA01 A
008 C00AA01 801-32361
008 D01AA01 NEW YORK
008 D02AA01 NY
008 D03AA01 10105
011 A00AA01 ALLIANCE FUND DISTRIBUTORS, INC.
011 B00AA01 8-30851
011 C01AA01 NEW YORK
011 C02AA01 NY
011 C03AA01 10105
012 A00AA01 ALLIANCE FUND SERVICES, INC.
012 B00AA01 84-001187
012 C01AA01 SECAUCUS
012 C02AA01 NJ
012 C03AA01 07096
013 A00AA01 PRICEWATERHOUSECOOPERS LLP
<PAGE> PAGE 2
013 B01AA01 NEW YORK
013 B02AA01 NY
013 B03AA01 10036
014 A00AA01 DONALDSON, LUFKIN & JENRETTE SECURITIES CORP.
014 B00AA01 8-00017574
015 A00AA01 THE BANK OF NEW YORK
015 B00AA01 C
015 C01AA01 NEW YORK
015 C02AA01 NY
015 C03AA01 10286
015 E01AA01 X
018 00AA00 Y
019 A00AA00 Y
019 B00AA00 51
019 C00AA00 ALLIANCECA
020 A000001 SALOMON SMITH BARNEY HOLDINGS, INC.
020 B000001 13-1912900
020 C000001 59
020 A000002 MERRILL LYNCH & CO., INC.
020 B000002 13-5674085
020 C000002 40
020 A000003 LEHMAN BROTHERS, INC.
020 B000003 13-2518466
020 C000003 38
020 A000004 GOLDMAN SACHS & CO., INC.
020 B000004 13-5108880
020 C000004 34
020 A000005 MORGAN STANLEY & CO., INC.
020 B000005 13-2655998
020 C000005 21
020 A000006 PAINWEBBER, INC.
020 B000006 13-2638166
020 C000006 18
020 A000007 MORGAN (J.P.) & CO., INC.
020 B000007 13-3224016
020 C000007 17
020 A000008 BEAR STEARNS COS., INC.
020 B000008 13-3299429
020 C000008 14
020 A000009 C.S. FIRST BOSTON CORP.
020 B000009 00-0000000
020 C000009 13
020 A000010 BRIDGE TRADING CO.
020 B000010 43-1450530
020 C000010 10
021 000000 339
022 A000001 DIRECT
022 B000001 N/A
022 C000001 865813
022 D000001 0
022 A000002 GENERAL ELECTRIC CREDIT CORP.
<PAGE> PAGE 3
022 B000002 N/A
022 C000002 500365
022 D000002 0
022 A000003 PRUDENTIAL SECURITIES, INC.
022 B000003 22-2347336
022 C000003 140415
022 D000003 1016
022 A000004 FORD MOTOR CREDIT CORP.
022 B000004 13-5659485
022 C000004 98412
022 D000004 0
022 A000005 MERRILL LYNCH & CO., INC.
022 B000005 13-5674085
022 C000005 19828
022 D000005 5386
022 A000006 ALLIANCE FUND SERVICES, INC.
022 B000006 N/A
022 C000006 23836
022 D000006 0
022 A000007 MORGAN STANLEY & CO., INC.
022 B000007 13-2655998
022 C000007 16401
022 D000007 4094
022 A000008 LEHMAN BROTHERS, INC.
022 B000008 13-2518466
022 C000008 10447
022 D000008 3694
022 A000009 SALOMON SMITH BARNEY HOLDINGS, INC.
022 B000009 13-1912900
022 C000009 5611
022 D000009 3710
022 A000010 MONTGOMERY SECURITIES, INC.
022 B000010 94-1701676
022 C000010 4777
022 D000010 3951
023 C000000 1715214
023 D000000 35269
026 A000000 N
026 B000000 N
026 C000000 N
026 D000000 N
026 E000000 N
026 F000000 N
026 G010000 N
026 G020000 N
026 H000000 N
027 000000 Y
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<PAGE> PAGE 4
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031 B00AA00 0
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033 00AA00 0
034 00AA00 Y
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038 00AA00 0
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041 00AA00 Y
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<PAGE> PAGE 5
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<PAGE> PAGE 6
056 00AA00 Y
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<PAGE> PAGE 7
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<PAGE> PAGE 8
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<PAGE> PAGE 9
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080 A00AA00 ICI MUTUAL
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080 C00AA00 83000
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<PAGE> PAGE 10
086 F02AA00 0
024 000100 Y
025 A000101 MORGAN STANLEY, DEAN WITTER, DISCOVER & CO.
025 B000101 13-2655998
025 C000101 E
025 D000101 10149
025 A000102 THE GOLDMAN SACHS GROUP, INC.
025 B000102 13-5108880
025 C000102 E
025 D000102 362
025 A000103 CITIGROUP, INC.
025 B000103 13-1912900
025 C000103 E
025 D000103 57
025 D000104 0
025 D000105 0
025 D000106 0
025 D000107 0
025 D000108 0
SIGNATURE GUY NORDAHL
TITLE ASST.VICE PRESIDENT
<TABLE> <S> <C>
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<CIK> 0001062417
<NAME> ALLIANCE SELECT INVESTOR SERIES, INC.
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<NAME> PREMIER PORTFOLIO CLASS A SHARES
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<PERIOD-TYPE> 12-MOS
<FISCAL-YEAR-END> OCT-31-1999
<PERIOD-START> NOV-01-1998
<PERIOD-END> OCT-31-1999
<INVESTMENTS-AT-COST> 218,181,827
<INVESTMENTS-AT-VALUE> 270,040,963
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<PAID-IN-CAPITAL-COMMON> 209,160,079
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</TABLE>
Securities Purchased in Underwritings Involving
Trunsactions with Donaldson, Lufkin, & Jenrette Securities
Corporation Subject to Rule 10f-3 Under the Investment
Company Act of 1940
10f-3 TRANSACTIONS FOR THE PERIOD MAY 1, 1999
THROUGH OCTOBER 31, 1999
Date Shares Price per
Security* Purchased Purchased Share
Goldman Sachs Group 5/3/99 6,300 $53.00
Flycast Communications Corp. 5/4/99 800 $25.00
Clear Channel Communications 5/19/99 21,900 $70.63
CAIS Internet Inc. 5/20/99 1,200 $19.00
Juno Online Services 5/20/99 900 $13.00
Starmedia Network Inc. 5/25/99 2,300 $15.00
Internet.com 6/25/99 2,200 $14.00
Persistence Software, Inc. 6/25/99 700 $11.00
E-Loan, Inc. 6/28/99 300 $14.00
Network Plus Corp. 6/29/99 4,000 $16.00
Commerce One 7/1/99 1,600 $21.00
Liquid Auto 7/9/99 1,200 $15.00
Commtouch Software Ltd. 7/13/99 1,200 $16.00
Engage Technologies, Inc. 7/19/99 1,800 $15.00
Insweb Corp 7/22/99 2,100 $17.00
Focal Communications 7/27/99 6,700 $13.00
Liberate Technologies 7/27/99 2,000 $16.00
Digex, Inc. 7/29/99 3,900 $17.00
Net2Phone, Inc. 7/29/99 1,200 $15.00
1-800 Flowers.com, Inc. 8/2/99 900 $21.00
Homestore.com 8/4/99 4,800 $20.00
Agile Software Corp. 8/19/99 400 $21.00
Foundary Networks 9/28/99 2,300 $25.00
Internap Network Services Corp. 9/29/99 3,100 $20.00
Crossroads Systems, Inc. 10/19/99 300 $18.00
Aether Systems, Inc. 10/20/99 2,500 $16.00
Predictive Systems, Inc. 10/27/99 500 $18.00
% of
Shares Total Offering
Purchased Shares Purchased Shares
By Fund Offered By Purchased Held
Group (000) Group(1) From 05/31/99
1,247,900 60,000 2.08% Goldman Sachs 6,300
29,100 3,000 0.97% Alex Brown & Sons 0
940,000 20,000 4.70% Morgan Stanley 21,900
45,900 6,000 0.77% Bear Stearns 0
33,200 6,500 0.51% Smith Barney 0
81,400 7,000 1.16% Goldman Sachs 0
81,800 3,400 2.41% Piper Jaffray 0
25,100 3,000 0.84% Robertson, Stephens & Co. 0
22,700 3,500 0.65% Goldman Sachs 0
283,200 8,000 3.54% Goldman Sachs 0
59,000 3,300 1.79% CS First Boston 0
32,000 4,200 0.76% Lehman Brothers 0
2,000 3,000 1.40% Piper Jaffray 0
63,000 6,000 1.05% Goldman Sachs 0
72,800 5,000 1.46% Goldman Sachs 0
235,600 9,950 2.37% Solomon Smith Barney 0
70,700 6,250 1.13% CS First Boston 0
135,600 10,000 1.36% Bear Stearns 0
41,900 5,400 0.78% Hambrech & Quist, Inc." 0
33,700 6,000 0.56% Goldman Sachs 0
157,400 7,000 2.25% Morgan Stanley 0
13,000 3,000 0.43% Morgan Stanley 0
83,500 5,000 1.67% Norwest Investment Services 0
112,200 8,700 1.29% Morgan Stanley 0
9,500 3,500 0.27% Cowen & Co. 0
89,400 6,000 1.49% Merrill Lynch 0
31,300 4,000 0.78% Robertson, Stephens & Co. 0
* Unless otherwise indicated, the securities were part of an
issue registered under the Securities Act of 1933 and offering
to the public.
** Indicates the purchase of an Eligible Rule 144A Security
1) Purchases by all Alliance Funds, including the Fund, may
not exceed:
a) if purchased in an offering other than an Eligible Rule 144A
Offering, 25% of the principle amount of the offering of such
class; or
b) if purchased in an Eligible Rule 144A Offering, 25% of the
total of (i) the principle amount of the offering of such class
sold by underwriters of members of the selling syndicate to
qualified institutional buyers, plus (ii) the principle amount
of the offering of such class in any concurrent public offering.
Report of Independent Accountants
To the Board of Directors and Shareholders of
Alliance Select Investor Series, Inc. - Premier Portfolio
In planning and performing our audit of the financial
statements of Alliance Select Investor Series, Inc.
- - Premier Portfolio (the "Fund") for the year ended
October 31, 1999, we considered its internal control,
including control activities for safeguarding securities,
in order to determine our auditing procedures for the
purpose of expressing our opinion on the financial
statements and to comply with the requirements of Form
N-SAR, not to provide assurance on internal control.
The management of the Fund is responsible for establishing
and maintaining internal control. In fulfilling this
responsibility, estimates and judgements by management
are required to assess the expected benefits and related
costs of controls. Generally, controls that are relevant
to an audit pertain to the entity's objective of preparing
financial statements for external purposes that are fairly
presented in conformity with generally accepted accounting
principles. Those controls include the safeguarding of
assets against unauthorized acquisition, use or disposition.
Because of inherent limitations in internal control, error
or fraud may occur and not be detected. Also, projection
of any evaluation of internal control to future periods is
subject to the risk that it may become inadequate because
of changes in conditions or that the effectiveness of the
design and operation may deteriorate.
Our consideration of internal control would not necessarily
disclose all matters in internal control that might be
material weaknesses under standards established by the
American Institute of Certified Public Accountants.
A material weakness is a condition in which the design
or operation of one or more of the internal control
components does not reduce to a relatively low level the
risk that misstatements caused by error or fraud in
amounts that would be material in relation to the financial
statements being audited may occur and not be detected within
a timely period by employees in the normal course of performing
their assigned functions. However, we noted no matters
involving internal control and its operation, including
controls for safeguarding securities, that we consider to be
material weaknesses as defined above as of October 31, 1999.
This report is intended solely for the information and use
of management and the Board of Directors of the Fund and the
Securities and Exchange Commission, and is not intended to be
and should not be used by anyone other than these specified
parties.
PricewaterhouseCoopers LLP
New York, NY 10036
December 16, 1999
