<PAGE>
This is filed pursuant to Rule 497(e).
File Nos. 333-8818 and 811-9176
<PAGE>
ALLIANCE CAPITAL [LOGO] (R) ALLIANCE SELECT INVESTOR SERIES, INC.
PREMIER PORTFOLIO
_________________________________________________________________
Supplement dated December 1, 1999 to Prospectus and Application
dated March 1, 1999 of Alliance Select Investor Series, Inc. -
Premier Portfolio (the "Fund")
This supplement supersedes certain information under the heading
"Purchase and Sale of Shares - How To Buy Shares". Effective
December 1, 1999, the minimum initial investment for all types of
investors is $10,000. The Fund's Subscription Application is
correspondingly modified.
_________________________________________________
YOU SHOULD RETAIN THIS SUPPLEMENT WITH YOUR PROSPECTUS FOR FUTURE
REFERENCE.
(R) This is a registered mark used under license from the owner,
Alliance Capital Management L.P.
<PAGE>
This is filed pursuant to Rule 497(e).
File Nos. 333-8818 and 811-9176
<PAGE>
ALLIANCE CAPITAL [LOGO] (R) ALLIANCE SELECT INVESTOR SERIES, INC.
PREMIER PORTFOLIO
_________________________________________________________________
Supplement dated December 1, 1999 to the Statement of Additional
Information dated March 1, 1999 of Alliance Select Investor
Series, Inc. - Premier Portfolio (the "Fund")
This supplement supersedes certain information under the headings
"Purchase of Shares - Statement of Intention" and "Shareholder
Services - Automatic Investment Program". Effective December 1,
1999, the minimum initial purchase of shares for all types of
investors is $10,000.
_________________________________________________
YOU SHOULD RETAIN THIS SUPPLEMENT WITH YOUR STATEMENT OF
ADDITIONAL INFORMATION FOR FUTURE REFERENCE.
(R) This is a registered mark used under license from the owner,
Alliance Capital Management L.P.
00250242.AK3
