ALLIANCE SELECT INVESTOR SERIES FUND INC
485BPOS, EX-99.A(4), 2000-07-07
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                                                   Exhibit (a)(4)

              ALLIANCE SELECT INVESTOR SERIES, INC.

                     ARTICLES SUPPLEMENTARY

         Alliance Select Investor Series, Inc., a Maryland
corporation having its principal office in Maryland in the City
of Baltimore (hereinafter called the "Corporation"), certifies
that:

         FIRST:  The Board of Directors of the Corporation hereby
increases the aggregate number of shares of capital stock that
the Corporation has authority to issue by 9,000,000,000 shares
and classifies such additional shares as 3,000,000,000 shares of
Class A Common Stock of the Biotechnology Portfolio,
3,000,000,000 shares of Class B Common Stock of the Biotechnology
Portfolio and 3,000,000,000 shares of Class C Common Stock of the
Biotechnology Portfolio. The Biotechnology Portfolio is referred
to herein as the "Portfolio."

         SECOND:  The shares of the Class A Common Stock, Class B
Common Stock and Class C Common Stock of the Portfolio as so
classified by the Board of Directors of the Corporation shall
have the preferences, conversion and other rights, voting powers,
restrictions, limitations as to dividends, qualifications and
terms and conditions of redemption set forth in Article FIFTH of
the Corporation's Articles of Incorporation, as amended, except
to the extent that any such provisions relate specifically only
to other classes of Common Stock of the Corporation, and shall be
subject to all provisions of the Charter relating to stock of the
Corporation generally, and those set forth as follows:

              (1)  The assets attributable to the Class A Common
         Stock, Class B Common Stock and Class C Common Stock of
         the Portfolio shall be invested in the same investment
         portfolio of the Corporation.

              (2)  Shares of each of the Class A Common Stock,
         Class B Common Stock and Class C Common Stock of the
         Portfolio shall be entitled to such dividends or
         distributions, in stock or in cash or both, as may be
         declared from time to time by the Board of Directors
         with respect to such class.  Specifically, and without
         limiting the generality of the foregoing, the dividends
         and distributions of investment income and capital gains
         with respect to the Class A Common Stock, Class B Common
         Stock and Class C Common Stock of the Portfolio shall be
         in such amounts, which may vary among the classes, as
         may be declared from time to time by the Board of
         Directors of the Corporation, and such dividends and



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         distributions may vary among the classes of the
         Portfolio to reflect differing allocations of the
         expenses of the Corporation among the holders of the
         classes and any resultant differences among the net
         asset values per share of the classes, to such extent
         and for such purposes as the Board of Directors of the
         Corporation may deem appropriate.  The Board of
         Directors may provide that dividends shall be payable
         only with respect to those shares of stock that have
         been held of record continuously by the stockholder for
         a specified period, not to exceed 72 hours, prior to the
         record date of the dividend.  The allocation of
         investment income, realized and unrealized capital gains
         and losses, expenses and liabilities of the Corporation
         and amounts distributable in the event of dissolution of
         the Corporation or liquidation of the Corporation or of
         the Portfolio among the various classes of the Portfolio
         shall be determined by the Board of Directors of the
         Corporation in a manner that is consistent with the
         Investment Company Act of 1940, the rules and
         regulations thereunder, and the interpretations thereof,
         in each case as from time to time amended, modified or
         superseded.  The determination of the Board of Directors
         shall be conclusive as to the allocation of investment
         income and realized and unrealized capital gains and
         losses, expenses and liabilities (including accrued
         expenses and reserves) and assets to a particular class
         or classes.

              (3)  The proceeds of the redemption of a share
         (including a fractional share) of any class of capital
         stock of the Portfolio shall be reduced by the amount of
         any contingent deferred sales charge, redemption fee or
         other amount payable on such redemption pursuant to the
         terms of issuance of such share.

              (4)  Except as provided below, on each matter
         submitted to a vote of the holders of the Class A Common
         Stock, Class B Common Stock and Class C Common Stock of
         the Portfolio, each such holder shall be entitled to one
         vote for each share standing in his or her name on the
         books of the Corporation.  Subject to any applicable
         requirements of the Investment Company Act of 1940, as
         from time to time in effect, or rules or orders of the
         Securities and Exchange Commission or any successor
         thereto, or other applicable law, all such holders of
         shares of stock shall vote as a single class except with
         respect to any matter which affects only one or more
         (but less than all) classes of stock, in which case only
         the holders of shares of the classes affected shall be
         entitled to vote.  Without limiting the generality of


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         the foregoing, and subject to any applicable
         requirements of the Investment Company Act of 1940, as
         from time to time in effect, or rules or orders of the
         Securities and Exchange Commission or any successor
         thereto, or other applicable law,  the holders of the
         Class A Common Stock, Class B Common Stock and Class C
         Common Stock, respectively, of the Portfolio shall have
         (i) exclusive voting rights with respect to any matter
         submitted to a vote of stockholders that affects only
         holders of the applicable class of the Portfolio and
         (ii) no voting rights with respect to any other matter
         that affects one or more of such other classes or series
         of Common Stock, but not the class or series of which
         they are holders.

              (5)  At such times as may be determined by the
         Board of Directors (or with the authorization of the
         Board of Directors, by the officers of the Corporation)
         in accordance with the Investment Company Act of 1940,
         applicable rules and regulations thereunder and
         applicable rules and regulations of the National
         Association of Securities Dealers, Inc. and from time to
         time reflected in the registration statement of the
         Corporation (the "Corporation's Registration
         Statement"), shares of a particular class of stock of
         the Portfolio or certain shares of a particular class of
         stock of the Portfolio may be automatically converted
         into shares of another class of stock of the Portfolio
         based on the relative net asset values of such classes
         at the time of conversion, subject, however, to any
         conditions of conversion that may be imposed by the
         Board of Directors (or with the authorization of the
         Board of Directors, by the officers of the Corporation)
         and reflected in the Corporation's Registration
         Statement.  The terms and conditions of such conversion
         may vary within and among the classes to the extent
         determined by the Board of Directors (or with the
         authorization of the Board of Directors, by the officers
         of the Corporation) and set forth in the Corporation's
         Registration Statement.

         THIRD:    A.  Immediately before the increase in
authorized capital stock provided for herein, the total number of
shares of stock of all classes which the Corporation had
authority to issue was 18,000,000,000 shares, the par value of
each share of stock being $.001, with an aggregate par value of
$18,000,000, classified as follows:

                         Class A        Class B        Class C
Name of Portfolio     Common Stock   Common Stock   Common Stock



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Premier Portfolio     3,000,000,000  3,000,000,000  3,000,000,000

Technology Portfolio  3,000,000,000  3,000,000,000  3,000,000,000

                   B.  Immediately after the increase in
authorized capital stock provided for herein, the total number of
shares of stock of all classes which the Corporation has
authority to issue is 27,000,000,000 shares, the par value of
each share of stock being $.001, with an aggregate par value of
$27,000,000, classified as follows:

                         Class A        Class B        Class C
Name of Portfolio     Common Stock   Common Stock   Common Stock

Premier Portfolio     3,000,000,000  3,000,000,000  3,000,000,000

Technology Portfolio  3,000,000,000  3,000,000,000  3,000,000,000

Biotechnology
Portfolio             3,000,000,000  3,000,000,000  3,000,000,000

         FOURTH:  The Corporation is registered as an open-end
company under the Investment Company Act of 1940.

         FIFTH:  The total number of shares that the Corporation
has authority to issue has been increased by the Board of
Directors of the Corporation in accordance with Section 2-105(c)
of the Maryland General Corporation Law.

         SIXTH:  The shares aforesaid have been duly classified
by the Corporation's Board of Directors pursuant to authority and
power contained in the Corporation's Articles of Incorporation.

         IN WITNESS WHEREOF, Alliance Select Investor Series,
Inc. has caused these Articles Supplementary to be executed by
the Chairman of the Board of Directors of the Corporation and
witnessed by its Secretary as of this 22nd day of June, 2000.
The Chairman of the Board of Directors of the Corporation who
signed these Articles Supplementary acknowledges them to be the
act of the Corporation and states under the penalties of perjury
that, to the best of his knowledge, information and belief, the
matters and facts set forth herein relating to authorization and
approval hereof are true in all material respects.

                           ALLIANCE SELECT INVESTOR SERIES, INC.

                               /s/John D. Carifa
                           By: _________________________________
                               John D. Carifa
                               Chairman and President



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WITNESS:

/s/ Edmund P. Bergan
______________________________
Edmund P. Bergan
Secretary















































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00250432.AA5



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